Sylvain Meloche - Publications

Université de Montréal, Montréal, Canada 
Microbiology Biology, Pharmacy

85 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Girondel C, Meloche S. Interleukin-17 Receptor D in Physiology, Inflammation and Cancer. Frontiers in Oncology. 11: 656004. PMID 33833999 DOI: 10.3389/fonc.2021.656004  0.52
2020 Girondel C, Lévesque K, Langlois MJ, Pasquin S, Saba-El-Leil MK, Rivard N, Friesel R, Servant MJ, Gauchat JF, Lesage S, Meloche S. Loss of interleukin-17 receptor D promotes chronic inflammation-associated tumorigenesis. Oncogene. PMID 33177649 DOI: 10.1038/s41388-020-01540-4  0.52
2019 Soulez M, Saba-El-Leil MK, Turgeon B, Mathien S, Coulombe P, Klinger S, Rousseau J, Lévesque K, Meloche S. Reevaluation of the Role of ERK3 in Perinatal Survival and Post-Natal Growth Using New Genetically-Engineered Mouse Models. Molecular and Cellular Biology. PMID 30642949 DOI: 10.1128/Mcb.00527-18  0.36
2017 Pyakurel A, Balmer D, Saba-El-Leil MK, Kizilyaprak C, Daraspe J, Humbel BM, Voisin L, Le YZ, von Lintig J, Meloche S, Roduit R. Loss of ERK1/2 in the retinal pigment epithelium leads to RPE65 decrease and retinal degeneration. Molecular and Cellular Biology. PMID 29038159 DOI: 10.1128/MCB.00295-17  0.52
2017 Mathien S, Déléris P, Soulez M, Voisin L, Meloche S. The Deubiquitinating Enzyme USP20 Regulates ERK3 Stability and Biological Activity. Molecular and Cellular Biology. PMID 28167606 DOI: 10.1128/Mcb.00432-16  0.52
2016 Duhamel S, Girondel C, Dorn JF, Tanguay PL, Voisin L, Smits R, Maddox PS, Meloche S. Deregulated ERK1/2 MAP kinase signaling promotes aneuploidy by a Fbxw7β-Aurora A pathway. Cell Cycle (Georgetown, Tex.). 0. PMID 27152455 DOI: 10.1080/15384101.2016.1183851  0.56
2016 Frémin C, Guégan JP, Plutoni C, Mahaffey J, Philips MR, Emery G, Meloche S. ERK1/2-induced phosphorylation of R-Ras GTPases stimulates their oncogenic potential Oncogene. DOI: 10.1038/onc.2016.122  0.32
2015 Lavallée VP, Baccelli I, Krosl J, Wilhelm B, Barabé F, Gendron P, Boucher G, Lemieux S, Marinier A, Meloche S, Hébert J, Sauvageau G. The transcriptomic landscape and directed chemical interrogation of MLL-rearranged acute myeloid leukemias. Nature Genetics. 47: 1030-7. PMID 26237430 DOI: 10.1038/Ng.3371  0.32
2015 Grote D, Moison C, Duhamel S, Chagraoui J, Girard S, Yang J, Mayotte N, Coulombe Y, Masson JY, Brown GW, Meloche S, Sauvageau G. E4F1 is a master regulator of CHK1-mediated functions. Cell Reports. 11: 210-9. PMID 25843717 DOI: 10.1016/J.Celrep.2015.03.019  0.32
2014 Bordeleau ME, Aucagne R, Chagraoui J, Girard S, Mayotte N, Bonneil E, Thibault P, Pabst C, Bergeron A, Barabé F, Hébert J, Sauvageau M, Boutonnet C, Meloche S, Sauvageau G. UBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activity. Blood. 124: 2362-9. PMID 25185265 DOI: 10.1182/Blood-2014-01-548651  0.32
2014 Redwan IN, Dyrager C, Solano C, Fernández de Trocóniz G, Voisin L, Bliman D, Meloche S, Grøtli M. Towards the development of chromone-based MEK1/2 modulators. European Journal of Medicinal Chemistry. 85: 127-38. PMID 25078316 DOI: 10.1016/J.Ejmech.2014.07.018  0.52
2014 Marquis M, Daudelin JF, Boulet S, Sirois J, Crain K, Mathien S, Turgeon B, Rousseau J, Meloche S, Labrecque N. The catalytic activity of the mitogen-activated protein kinase extracellular signal-regulated kinase 3 is required to sustain CD4+ CD8+ thymocyte survival. Molecular and Cellular Biology. 34: 3374-87. PMID 25002529 DOI: 10.1128/Mcb.01701-13  0.36
2014 Marquis M, Boulet S, Mathien S, Rousseau J, Thébault P, Daudelin JF, Rooney J, Turgeon B, Beauchamp C, Meloche S, Labrecque N. The non-classical MAP kinase ERK3 controls T cell activation. Plos One. 9: e86681. PMID 24475167 DOI: 10.1371/Journal.Pone.0086681  0.36
2014 Deschênes-Simard X, Kottakis F, Meloche S, Ferbeyre G. ERKs in cancer: friends or foes? Cancer Research. 74: 412-9. PMID 24408923 DOI: 10.1158/0008-5472.Can-13-2381  0.32
2013 Courcelles M, Frémin C, Voisin L, Lemieux S, Meloche S, Thibault P. Phosphoproteome dynamics reveal novel ERK1/2 MAP kinase substrates with broad spectrum of functions. Molecular Systems Biology. 9: 669. PMID 23712012 DOI: 10.1038/Msb.2013.25  0.32
2013 Deschênes-Simard X, Gaumont-Leclerc MF, Bourdeau V, Lessard F, Moiseeva O, Forest V, Igelmann S, Mallette FA, Saba-El-Leil MK, Meloche S, Saad F, Mes-Masson AM, Ferbeyre G. Tumor suppressor activity of the ERK/MAPK pathway by promoting selective protein degradation. Genes & Development. 27: 900-15. PMID 23599344 DOI: 10.1101/Gad.203984.112  0.32
2013 Romeo Y, Moreau J, Zindy PJ, Saba-El-Leil M, Lavoie G, Dandachi F, Baptissart M, Borden KLB, Meloche S, Roux PP. RSK regulates activated BRAF signalling to mTORC1 and promotes melanoma growth Oncogene. 32: 2917-2926. PMID 22797077 DOI: 10.1038/Onc.2012.312  0.32
2012 Trost M, Sauvageau M, Hérault O, Deleris P, Pomiès C, Chagraoui J, Mayotte N, Meloche S, Sauvageau G, Thibault P. Posttranslational regulation of self-renewal capacity: insights from proteome and phosphoproteome analyses of stem cell leukemia. Blood. 120: e17-27. PMID 22802335 DOI: 10.1182/Blood-2011-12-397844  0.32
2012 van Zuylen WJ, Doyon P, Clément JF, Khan KA, D'Ambrosio LM, Dô F, St-Amant-Verret M, Wissanji T, Emery G, Gingras AC, Meloche S, Servant MJ. Proteomic profiling of the TRAF3 interactome network reveals a new role for the ER-to-Golgi transport compartments in innate immunity. Plos Pathogens. 8: e1002747. PMID 22792062 DOI: 10.1371/Journal.Ppat.1002747  0.32
2012 Meloche S, Roux PP. F-box proteins elongate translation during stress recovery. Science Signaling. 5: pe25. PMID 22669843 DOI: 10.1126/Scisignal.2003163  0.32
2012 Duhamel S, Hébert J, Gaboury L, Bouchard A, Simon R, Sauter G, Basik M, Meloche S. Sef downregulation by Ras causes MEK1/2 to become aberrantly nuclear localized leading to polyploidy and neoplastic transformation. Cancer Research. 72: 626-35. PMID 22298595 DOI: 10.1158/0008-5472.Can-11-2126  0.52
2012 Bourbonnais E, Raymond VA, Ethier C, Nguyen BN, El-Leil MS, Meloche S, Bilodeau M. Liver fibrosis protects mice from acute hepatocellular injury. Gastroenterology. 142: 130-139.e4. PMID 21945831 DOI: 10.1053/J.Gastro.2011.09.033  0.32
2011 Ceccarelli DF, Tang X, Pelletier B, Orlicky S, Xie W, Plantevin V, Neculai D, Chou YC, Ogunjimi A, Al-Hakim A, Varelas X, Koszela J, Wasney GA, Vedadi M, Dhe-Paganon S, ... ... Meloche S, et al. An allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme. Cell. 145: 1075-87. PMID 21683433 DOI: 10.1016/J.Cell.2011.05.039  0.32
2011 Courcelles M, Lemieux S, Voisin L, Meloche S, Thibault P. ProteoConnections: a bioinformatics platform to facilitate proteome and phosphoproteome analyses. Proteomics. 11: 2654-71. PMID 21630457 DOI: 10.1002/Pmic.201000776  0.32
2011 Déléris P, Trost M, Topisirovic I, Tanguay PL, Borden KL, Thibault P, Meloche S. Activation loop phosphorylation of ERK3/ERK4 by group I p21-activated kinases (PAKs) defines a novel PAK-ERK3/4-MAPK-activated protein kinase 5 signaling pathway. The Journal of Biological Chemistry. 286: 6470-8. PMID 21177870 DOI: 10.1074/Jbc.M110.181529  0.32
2011 Kehat I, Davis J, Tiburcy M, Accornero F, Saba-El-Leil MK, Maillet M, York AJ, Lorenz JN, Zimmermann WH, Meloche S, Molkentin JD. Extracellular signal-regulated kinases 1 and 2 regulate the balance between eccentric and concentric cardiac growth. Circulation Research. 108: 176-83. PMID 21127295 DOI: 10.1161/Circresaha.110.231514  0.32
2011 Galisson F, Mahrouche L, Courcelles M, Bonneil E, Meloche S, Chelbi-Alix MK, Thibault P. A novel proteomics approach to identify SUMOylated proteins and their modification sites in human cells. Molecular & Cellular Proteomics : McP. 10: M110.004796. PMID 21098080 DOI: 10.1074/Mcp.M110.004796  0.32
2011 Servant MJ, Clément J, Meloche S. The IKK-related kinases, unsuspected culprits in oncogenesis? Atlas of Genetics and Cytogenetics in Oncology and Haematology. DOI: 10.4267/2042/44696  0.4
2010 Rousseau J, Klinger S, Rachalski A, Turgeon B, Déléris P, Vigneault E, Poirier-Héon JF, Davoli MA, Mechawar N, El Mestikawy S, Cermakian N, Meloche S. Targeted inactivation of Mapk4 in mice reveals specific nonredundant functions of Erk3/Erk4 subfamily mitogen-activated protein kinases. Molecular and Cellular Biology. 30: 5752-63. PMID 20956558 DOI: 10.1128/Mcb.01147-10  0.32
2010 Voisin L, Saba-El-Leil MK, Julien C, Frémin C, Meloche S. Genetic demonstration of a redundant role of extracellular signal-regulated kinase 1 (ERK1) and ERK2 mitogen-activated protein kinases in promoting fibroblast proliferation. Molecular and Cellular Biology. 30: 2918-32. PMID 20368360 DOI: 10.1128/Mcb.00131-10  0.52
2010 Tanguay PL, Rodier G, Meloche S. C-terminal domain phosphorylation of ERK3 controlled by Cdk1 and Cdc14 regulates its stability in mitosis. The Biochemical Journal. 428: 103-11. PMID 20236090 DOI: 10.1042/Bj20091604  0.56
2010 Boutonnet C, Tanguay PL, Julien C, Rodier G, Coulombe P, Meloche S. Phosphorylation of Ser72 does not regulate the ubiquitin ligase activity and subcellular localization of Skp2. Cell Cycle (Georgetown, Tex.). 9: 975-9. PMID 20160482 DOI: 10.4161/Cc.9.5.10915  0.56
2009 Coulombe P, Rodier G, Meloche S. [Cdc14B/Skp2/p27 : a novel cancer axis of evil?]. MéDecine Sciences : M/S. 25: 673-5. PMID 19765377 DOI: 10.1051/Medsci/2009258-9673  0.56
2009 White M, Ross H, Levesque S, Whittom L, Pelletier GB, Racine N, Meloche S, Voisin L. Effects of angiotensin-converting enzyme inhibitor versus valsartan on cellular signaling events in heart transplant. The Annals of Pharmacotherapy. 43: 831-9. PMID 19417110 DOI: 10.1345/Aph.1L602  0.32
2009 Granados DP, Tanguay PL, Hardy MP, Caron E, de Verteuil D, Meloche S, Perreault C. ER stress affects processing of MHC class I-associated peptides. Bmc Immunology. 10: 10. PMID 19220912 DOI: 10.1186/1471-2172-10-10  0.32
2009 Gharib M, Marcantonio M, Lehmann SG, Courcelles M, Meloche S, Verreault A, Thibault P. Artifactual sulfation of silver-stained proteins: implications for the assignment of phosphorylation and sulfation sites. Molecular & Cellular Proteomics : McP. 8: 506-18. PMID 18936056 DOI: 10.1074/Mcp.M800327-Mcp200  0.32
2008 Clément JF, Meloche S, Servant MJ. The IKK-related kinases: from innate immunity to oncogenesis. Cell Research. 18: 889-99. PMID 19160540 DOI: 10.1038/Cr.2008.273  0.4
2008 Voisin L, Julien C, Duhamel S, Gopalbhai K, Claveau I, Saba-El-Leil MK, Rodrigue-Gervais IG, Gaboury L, Lamarre D, Basik M, Meloche S. Activation of MEK1 or MEK2 isoform is sufficient to fully transform intestinal epithelial cells and induce the formation of metastatic tumors. Bmc Cancer. 8: 337. PMID 19014680 DOI: 10.1186/1471-2407-8-337  1
2008 Déléris P, Rousseau J, Coulombe P, Rodier G, Tanguay PL, Meloche S. Activation loop phosphorylation of the atypical MAP kinases ERK3 and ERK4 is required for binding, activation and cytoplasmic relocalization of MK5. Journal of Cellular Physiology. 217: 778-88. PMID 18720373 DOI: 10.1002/Jcp.21560  0.56
2008 Culjkovic B, Tan K, Orolicki S, Amri A, Meloche S, Borden KLB. The eIF4E RNA regulon promotes the Akt signaling pathway Journal of Cell Biology. 181: 51-63. PMID 18391071 DOI: 10.1083/Jcb.200707018  0.32
2008 Clément JF, Bibeau-Poirier A, Gravel SP, Grandvaux N, Bonneil E, Thibault P, Meloche S, Servant MJ. Phosphorylation of IRF-3 on Ser 339 generates a hyperactive form of IRF-3 through regulation of dimerization and CBP association. Journal of Virology. 82: 3984-96. PMID 18272581 DOI: 10.1128/Jvi.02526-07  0.32
2008 Rodier G, Coulombe P, Tanguay PL, Boutonnet C, Meloche S. Phosphorylation of Skp2 regulated by CDK2 and Cdc14B protects it from degradation by APC(Cdh1) in G1 phase. The Embo Journal. 27: 679-91. PMID 18239684 DOI: 10.1038/Emboj.2008.6  0.56
2007 Purcell NH, Wilkins BJ, York A, Saba-El-Leil MK, Meloche S, Robbins J, Molkentin JD. Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo. Proceedings of the National Academy of Sciences of the United States of America. 104: 14074-9. PMID 17709754 DOI: 10.1073/Pnas.0610906104  0.32
2007 Cellot S, Krosl J, Chagraoui J, Meloche S, Humphries RK, Sauvageau G. Sustained in vitro trigger of self-renewal divisions in Hoxb4hiPbx1(10) hematopoietic stem cells. Experimental Hematology. 35: 802-16. PMID 17577929 DOI: 10.1016/J.Exphem.2007.02.013  0.32
2007 Coulombe P, Meloche S. Atypical mitogen-activated protein kinases: structure, regulation and functions. Biochimica Et Biophysica Acta. 1773: 1376-87. PMID 17161475 DOI: 10.1016/J.Bbamcr.2006.11.001  0.36
2006 Bibeau-Poirier A, Gravel SP, Clément JF, Rolland S, Rodier G, Coulombe P, Hiscott J, Grandvaux N, Meloche S, Servant MJ. Involvement of the IkappaB kinase (IKK)-related kinases tank-binding kinase 1/IKKi and cullin-based ubiquitin ligases in IFN regulatory factor-3 degradation. Journal of Immunology (Baltimore, Md. : 1950). 177: 5059-67. PMID 17015689 DOI: 10.4049/Jimmunol.177.8.5059  0.32
2006 Chagraoui J, Niessen SL, Lessard J, Girard S, Coulombe P, Sauvageau M, Meloche S, Sauvageau G. E4F1: a novel candidate factor for mediating BMI1 function in primitive hematopoietic cells. Genes & Development. 20: 2110-20. PMID 16882984 DOI: 10.1101/Gad.1453406  0.32
2005 Martin NL, Saba-El-Leil MK, Sadekova S, Meloche S, Sauvageau G. EN2 is a candidate oncogene in human breast cancer. Oncogene. 24: 6890-901. PMID 16007149 DOI: 10.1038/Sj.Onc.1208840  0.32
2005 Pelletier S, Julien C, Popoff MR, Lamarche-Vane N, Meloche S. Cyclic AMP induces morphological changes of vascular smooth muscle cells by inhibiting a Rac-dependent signaling pathway. Journal of Cellular Physiology. 204: 412-22. PMID 15706595 DOI: 10.1002/Jcp.20308  0.4
2005 Rodier G, Makris C, Coulombe P, Scime A, Nakayama K, Nakayama KI, Meloche S. p107 inhibits G1 to S phase progression by down-regulating expression of the F-box protein Skp2. The Journal of Cell Biology. 168: 55-66. PMID 15631990 DOI: 10.1083/Jcb.200404146  0.56
2004 Seternes OM, Mikalsen T, Johansen B, Michaelsen E, Armstrong CG, Morrice NA, Turgeon B, Meloche S, Moens U, Keyse SM. Activation of MK5/PRAK by the atypical MAP kinase ERK3 defines a novel signal transduction pathway. The Embo Journal. 23: 4780-91. PMID 15577943 DOI: 10.1038/Sj.Emboj.7600489  0.32
2004 Coulombe P, Rodier G, Bonneil E, Thibault P, Meloche S. N-Terminal ubiquitination of extracellular signal-regulated kinase 3 and p21 directs their degradation by the proteasome. Molecular and Cellular Biology. 24: 6140-50. PMID 15226418 DOI: 10.1128/Mcb.24.14.6140-6150.2004  0.32
2004 Lips DJ, Bueno OF, Wilkins BJ, Purcell NH, Kaiser RA, Lorenz JN, Voisin L, Saba-El-Leil MK, Meloche S, Pouysségur J, Pagès G, De Windt LJ, Doevendans PA, Molkentin JD. MEK1-ERK2 signaling pathway protects myocardium from ischemic injury in vivo. Circulation. 109: 1938-41. PMID 15096454 DOI: 10.1161/01.Cir.0000127126.73759.23  0.32
2004 Meloche S, Vella FD, Voisin L, Ang SL, Saba-El-Leil M. Erk2 signaling and early embryo stem cell self-renewal. Cell Cycle (Georgetown, Tex.). 3: 241-3. PMID 14726711  0.52
2003 Wu C, Arcand M, Jansen G, Zhong M, Iouk T, Thomas DY, Meloche S, Whiteway M. Phosphorylation of the MAPKKK regulator Ste50p in Saccharomyces cerevisiae: a casein kinase I phosphorylation site is required for proper mating function. Eukaryotic Cell. 2: 949-61. PMID 14555477 DOI: 10.1128/Ec.2.5.949-961.2003  0.32
2003 Saba-El-Leil MK, Vella FD, Vernay B, Voisin L, Chen L, Labrecque N, Ang SL, Meloche S. An essential function of the mitogen-activated protein kinase Erk2 in mouse trophoblast development. Embo Reports. 4: 964-8. PMID 14502223 DOI: 10.1038/Sj.Embor.Embor939  0.52
2003 Julien C, Coulombe P, Meloche S. Nuclear export of ERK3 by a CRM1-dependent mechanism regulates its inhibitory action on cell cycle progression. The Journal of Biological Chemistry. 278: 42615-24. PMID 12915405 DOI: 10.1074/Jbc.M302724200  0.36
2003 Coulombe P, Rodier G, Pelletier S, Pellerin J, Meloche S. Rapid turnover of extracellular signal-regulated kinase 3 by the ubiquitin-proteasome pathway defines a novel paradigm of mitogen-activated protein kinase regulation during cellular differentiation. Molecular and Cellular Biology. 23: 4542-58. PMID 12808096 DOI: 10.1128/Mcb.23.13.4542-4558.2003  0.56
2003 Gingras B, Rodier G, Giasson E, Coulombe P, Chassagne C, Meloche S. Expression of angiotensin type II receptor downregulates Cdk4 synthesis and inhibits cell-cycle progression. Oncogene. 22: 2633-42. PMID 12730677 DOI: 10.1038/Sj.Onc.1206346  0.56
2003 Gennaro G, Ménard C, Giasson E, Michaud SE, Palasis M, Meloche S, Rivard A. Role of p44/p42 MAP kinase in the age-dependent increase in vascular smooth muscle cell proliferation and neointimal formation. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 204-10. PMID 12588760 DOI: 10.1161/01.Atv.0000053182.58636.Be  0.32
2003 Pelletier S, Duhamel F, Coulombe P, Popoff MR, Meloche S. Rho family GTPases are required for activation of Jak/STAT signaling by G protein-coupled receptors. Molecular and Cellular Biology. 23: 1316-33. PMID 12556491 DOI: 10.1128/Mcb.23.4.1316-1333.2003  0.4
2003 Gopalbhai K, Jansen G, Beauregard G, Whiteway M, Dumas F, Wu C, Meloche S. Negative regulation of MAPKK by phosphorylation of a conserved serine residue equivalent to Ser212 of MEK1. The Journal of Biological Chemistry. 278: 8118-25. PMID 12506122 DOI: 10.1074/Jbc.M211870200  0.32
2002 Coulombe P, Meloche S. Dual-tag prokaryotic vectors for enhanced expression of full-length recombinant proteins. Analytical Biochemistry. 310: 219-22. PMID 12423642 DOI: 10.1016/S0003-2697(02)00319-6  0.36
2002 Makris C, Voisin L, Giasson E, Tudan C, Kaplan DR, Meloche S. The Rb-family protein p107 inhibits translation by a PDK1-dependent mechanism. Oncogene. 21: 7891-6. PMID 12420226 DOI: 10.1038/Sj.Onc.1205964  0.32
2002 Voisin L, Foisy S, Giasson E, Lambert C, Moreau P, Meloche S. EGF receptor transactivation is obligatory for protein synthesis stimulation by G protein-coupled receptors. American Journal of Physiology. Cell Physiology. 283: C446-55. PMID 12107054 DOI: 10.1152/Ajpcell.00261.2001  0.32
2001 Charron F, Tsimiklis G, Arcand M, Robitaille L, Liang Q, Molkentin JD, Meloche S, Nemer M. Tissue-specific GATA factors are transcriptional effectors of the small GTPase RhoA. Genes & Development. 15: 2702-19. PMID 11641276 DOI: 10.1101/Gad.915701  0.32
2001 Rouleau JL, Kapuku G, Pelletier S, Gosselin H, Adam A, Gagnon C, Lambert C, Meloche S. Cardioprotective effects of ramipril and losartan in right ventricular pressure overload in the rabbit: importance of kinins and influence on angiotensin II type 1 receptor signaling pathway. Circulation. 104: 939-44. PMID 11514383 DOI: 10.1161/Hc3401.093149  0.32
2000 Meloche S, Pelletier S, Servant MJ. Functional cross-talk between the cyclic AMP and Jak/STAT signaling pathways in vascular smooth muscle cells. Molecular and Cellular Biochemistry. 212: 99-109. PMID 11108141 DOI: 10.1023/A:1007140606333  0.4
2000 Yen L, You XL, Al Moustafa AE, Batist G, Hynes NE, Mader S, Meloche S, Alaoui-Jamali MA. Heregulin selectively upregulates vascular endothelial growth factor secretion in cancer cells and stimulates angiogenesis Oncogene. 19: 3460-3469. PMID 10918604 DOI: 10.1038/Sj.Onc.1203685  0.32
2000 Meloche S, Gopalbhai K, Beatty BG, Scherer SW, Pellerin J. Chromosome mapping of the human genes encoding the MAP kinase kinase MEK1 (MAP2K1) to 15q21 and MEK2 (MAP2K2) to 7q32. Cytogenetics and Cell Genetics. 88: 249-52. PMID 10828601 DOI: 10.1159/000015530  1
1999 Bastien NR, Servant MJ, Gutkowska J, Meloche S, Lambert C. Downregulation of cardiac AT1-receptor expression and angiotensin II concentrations after long-term blockade of the renin-angiotensin system in cardiomyopathic hamsters Journal of Cardiovascular Pharmacology. 34: 402-406. PMID 10470999 DOI: 10.1097/00005344-199909000-00013  0.32
1998 Csank C, Schröppel K, Leberer E, Harcus D, Mohamed O, Meloche S, Thomas DY, Whiteway M. Roles of the Candida aibicans mitogen-activated protein kinase homolog, Cek1p, in hyphal development and systemic candidiasis Infection and Immunity. 66: 2713-2721. PMID 9596738 DOI: 10.1128/Iai.66.6.2713-2721.1998  0.32
1998 Gopalbhai K, Meloche S. Repression of mitogen-activated protein kinases ERK1/ERK2 activity by a protein tyrosine phosphatase in rat fibroblasts transformed by upstream oncoproteins. Journal of Cellular Physiology. 174: 35-47. PMID 9397154 DOI: 10.1002/(Sici)1097-4652(199801)174:1<35::Aid-Jcp5>3.0.Co;2-H  1
1997 Csank C, Makris C, Meloche S, Schröppel K, Röllinghoff M, Dignard D, Thomas DY, Whiteway M. Derepressed hyphal growth and reduced virulence in a VH1 family-related protein phosphatase mutant of the human pathogen Candida albicans Molecular Biology of the Cell. 8: 2539-2551. PMID 9398674 DOI: 10.1091/Mbc.8.12.2539  0.32
1997 Giasson E, Servant MJ, Meloche S. Cyclic AMP-mediated inhibition of angiotensin II-induced protein synthesis is associated with suppression of tyrosine phosphorylation signaling in vascular smooth muscle cells. The Journal of Biological Chemistry. 272: 26879-86. PMID 9341120 DOI: 10.1074/Jbc.272.43.26879  0.4
1997 Scimeca JC, Servant MJ, Dyer JO, Meloche S. Essential role of calcium in the regulation of MAP kinase phosphatase-1 expression Oncogene. 15: 717-725. PMID 9264412 DOI: 10.1038/Sj.Onc.1201231  0.32
1997 Saba-el-Leil MK, Malo D, Meloche S. Chromosomal localization of the mouse genes encoding the ERK1 and ERK2 isoforms of MAP kinases. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 8: 141-2. PMID 9060415 DOI: 10.1007/S003359900374  0.32
1996 Rajotte D, Sadowski HB, Haman A, Gopalbhai K, Meloche S, Liu L, Krystal G, Hoang T. Contribution of both STAT and SRF/TCF to c-fos promoter activation by granulocyte-macrophage colony-stimulating factor. Blood. 88: 2906-16. PMID 8874187 DOI: 10.1182/Blood.V88.8.2906.Bloodjournal8882906  1
1996 Servant MJ, Giasson E, Meloche S. Inhibition of growth factor-induced protein synthesis by a selective MEK inhibitor in aortic smooth muscle cells. The Journal of Biological Chemistry. 271: 16047-52. PMID 8663242 DOI: 10.1074/Jbc.271.27.16047  0.4
1995 Lambert C, Massillon Y, Meloche S. Upregulation of cardiac angiotensin II AT1 receptors in congenital cardiomyopathic hamsters Circulation Research. 77: 1001-1007. PMID 7554134 DOI: 10.1161/01.Res.77.5.1001  0.32
1993 Hivroz C, Mazerolles F, Soula M, Fagard R, Graton S, Meloche S, Sekaly RP, Fischer A. Human immunodeficiency virus gp120 and derived peptides activate protein tyrosine kinase p56lck in human CD4 T lymphocytes European Journal of Immunology. 23: 600-607. PMID 7680610  0.32
1992 Wakabayashi S, Sardet C, Fafournoux P, Counillon L, Meloche S, Pagés G, Pouysségur J. Structure function of the growth factor-activatable Na+/H+ exchanger (NHE1). Reviews of Physiology, Biochemistry and Pharmacology. 119: 157-86. PMID 1318573 DOI: 10.1007/3540551921_6  0.32
1991 Ansotegui IJ, Chow SC, Jeddi-Tehrani M, Meloche S, Pawson A, Sekaly RP, Mak TW, Wigzell H. Characterization of a monoclonal antibody directed against the phosphotyrosine kinase p56(lck), in human T cells Scandinavian Journal of Immunology. 33: 375-380. PMID 2017663 DOI: 10.1111/j.1365-3083.1991.tb01784.x  0.32
1991 Fleury S, Lamarre D, Meloche S, Ryu SE, Cantin C, Hendrickson WA, Sekaly RP. Mutational analysis of the interaction between CD4 and class II MHC: Class II antigens contact CD4 on a surface opposite the gp120-binding site Cell. 66: 1037-1049. PMID 1889086 DOI: 10.1016/0092-8674(91)90447-7  0.32
1990 Tremblay M, Meloche S, Sekaly RP, Wainberg MA. Complement receptor 2 mediates enhancement of human immunodeficiency virus 1 infection in epstein-barr virus-carrying B cells Journal of Experimental Medicine. 171: 1791-1796. PMID 2159052 DOI: 10.1084/Jem.171.5.1791  0.32
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