| Year |
Citation |
Score |
| 2018 |
Wang Q, Hagedorn C, Liu S. Adapted HCV JFH1 variant is capable of accommodating a large foreign gene insert and allows lower level HCV replication and viral production. International Journal of Biological Sciences. 14: 1211-1220. PMID 30123070 DOI: 10.7150/Ijbs.27411 |
0.362 |
|
| 2017 |
Aydin Y, Chedid M, Chava S, Danielle Williams D, Liu S, Hagedorn CH, Sumitran-Holgersson S, Reiss K, Moroz K, Lu H, Balart LA, Dash S. Activation of PERK-Nrf2 oncogenic signaling promotes Mdm2-mediated Rb degradation in persistently infected HCV culture. Scientific Reports. 7: 9223. PMID 28835697 DOI: 10.1038/S41598-017-10087-6 |
0.353 |
|
| 2016 |
Jarret A, McFarland AP, Horner SM, Kell A, Schwerk J, Hong M, Badil S, Joslyn RC, Baker DP, Carrington M, Hagedorn CH, Gale M, Savan R. Hepatitis-C-virus-induced microRNAs dampen interferon-mediated antiviral signaling. Nature Medicine. PMID 27841874 DOI: 10.1038/Nm.4211 |
0.357 |
|
| 2016 |
Hong M, Schwerk J, Lim C, Kell A, Jarret A, Pangallo J, Loo YM, Liu S, Hagedorn CH, Gale M, Savan R. Interferon lambda 4 expression is suppressed by the host during viral infection. The Journal of Experimental Medicine. PMID 27799623 DOI: 10.1084/Jem.20160437 |
0.394 |
|
| 2016 |
Kanth P, Bronner MP, Boucher KM, Burt R, Neklason DW, Hagedorn CH, Delker DA. Gene Signature in Sessile Serrated Polyps Identifies Colon Cancer Subtype. Cancer Prevention Research (Philadelphia, Pa.). PMID 27026680 DOI: 10.1158/1940-6207.Capr-15-0363 |
0.315 |
|
| 2015 |
Liu S, Chen R, Hagedorn CH. Tannic Acid Inhibits Hepatitis C Virus Entry into Huh7.5 Cells. Plos One. 10: e0131358. PMID 26186636 DOI: 10.1371/Journal.Pone.0131358 |
0.374 |
|
| 2015 |
Meyer K, Kwon YC, Liu S, Hagedorn CH, Ray RB, Ray R. Interferon-α inducible protein 6 impairs EGFR activation by CD81 and inhibits hepatitis C virus infection. Scientific Reports. 5: 9012. PMID 25757571 DOI: 10.1038/Srep09012 |
0.367 |
|
| 2015 |
Hagedorn C, Khaidakov M, Lai KK, Lamps LW, Kanth P, Glazko G, Delker D, Goyne H, Roudachevski D. Mo1973 Immunohistochemical Markers Differentiating Colonic Sessile Serrated Adenomas/Polyps (SSA/Ps) From Hyperplastic Polyps Gastroenterology. 148: S-755. DOI: 10.1016/S0016-5085(15)32582-8 |
0.338 |
|
| 2015 |
Kanth P, Bronner MP, Neklason D, Burt RW, Hagedorn C, Delker D. Sa1947 RNA Sequencing Identifies Unique and Commonly Expressed Genes in Sessile Serrated and Hyperplastic Colon Polyps and Demonstrates Molecular Overlap Between Syndromic and Sporadic Sessile Serrated Polyps Gastroenterology. 148. DOI: 10.1016/S0016-5085(15)31220-8 |
0.315 |
|
| 2014 |
Pothineni NV, Delongchamp R, Vallurupalli S, Ding Z, Dai Y, Hagedorn CH, Mehta JL. Impact of hepatitis C seropositivity on the risk of coronary heart disease events. The American Journal of Cardiology. 114: 1841-5. PMID 25438910 DOI: 10.1016/J.Amjcard.2014.09.020 |
0.352 |
|
| 2014 |
Delker DA, McGettigan BM, Kanth P, Pop S, Neklason DW, Bronner MP, Burt RW, Hagedorn CH. RNA sequencing of sessile serrated colon polyps identifies differentially expressed genes and immunohistochemical markers. Plos One. 9: e88367. PMID 24533081 DOI: 10.1371/Journal.Pone.0088367 |
0.324 |
|
| 2014 |
Liu S, Chen R, Hagedorn CH. Direct visualization of hepatitis C virus-infected Huh7.5 cells with a high titre of infectious chimeric JFH1-EGFP reporter virus in three-dimensional Matrigel cell cultures. The Journal of General Virology. 95: 423-33. PMID 24243732 DOI: 10.1099/Vir.0.055772-0 |
0.356 |
|
| 2014 |
McFarland AP, Horner SM, Jarret A, Joslyn RC, Bindewald E, Shapiro BA, Delker DA, Hagedorn CH, Carrington M, Gale M, Savan R. The favorable IFNL3 genotype escapes mRNA decay mediated by AU-rich elements and hepatitis C virus-induced microRNAs. Nature Immunology. 15: 72-9. PMID 24241692 DOI: 10.1038/Ni.2758 |
0.383 |
|
| 2014 |
Chandra PK, Bao L, Song K, Aboulnasr FM, Baker DP, Shores N, Wimley WC, Liu S, Hagedorn CH, Fuchs SY, Wu T, Balart LA, Dash S. HCV infection selectively impairs type I but not type III IFN signaling. The American Journal of Pathology. 184: 214-29. PMID 24215913 DOI: 10.1016/J.Ajpath.2013.10.005 |
0.342 |
|
| 2014 |
Delker D, Kanth P, Bronner MP, Burt RW, Hagedorn C. Tu1666 RNA Sequencing of Sessile Serrated Colon Polyps Identifies Differentially Expressed Genes and Immunohistochemical Markers Gastroenterology. 146. DOI: 10.1016/S0016-5085(14)62942-5 |
0.331 |
|
| 2013 |
Smalling RL, Delker DA, Zhang Y, Nieto N, McGuiness MS, Liu S, Friedman SL, Hagedorn CH, Wang L. Genome-wide transcriptome analysis identifies novel gene signatures implicated in human chronic liver disease. American Journal of Physiology. Gastrointestinal and Liver Physiology. 305: G364-74. PMID 23812039 DOI: 10.1152/Ajpgi.00077.2013 |
0.322 |
|
| 2013 |
Negash AA, Ramos HJ, Crochet N, Lau DT, Doehle B, Papic N, Delker DA, Jo J, Bertoletti A, Hagedorn CH, Gale M. IL-1β production through the NLRP3 inflammasome by hepatic macrophages links hepatitis C virus infection with liver inflammation and disease. Plos Pathogens. 9: e1003330. PMID 23633957 DOI: 10.1371/Journal.Ppat.1003330 |
0.353 |
|
| 2013 |
Delker DA, McGettigan B, Kanth P, Neklason D, Bronner MP, Burt RW, Hagedorn CH. Su1992 Next Generation Sequencing Analysis of 5’ Capped RNAs Identifies Novel Differentially Expressed Genes in Sessile Serrated Colon Polyps Gastroenterology. 144: S-526. DOI: 10.1016/S0016-5085(13)61954-X |
0.325 |
|
| 2012 |
Liu S, Xiao L, Nelson C, Hagedorn CH, Hagedorn C. A cell culture adapted HCV JFH1 variant that increases viral titers and permits the production of high titer infectious chimeric reporter viruses. Plos One. 7: e44965. PMID 23028707 DOI: 10.1371/Journal.Pone.0044965 |
0.361 |
|
| 2012 |
Papic N, Maxwell CI, Delker DA, Liu S, Heale BS, Hagedorn CH. RNA-sequencing analysis of 5' capped RNAs identifies many new differentially expressed genes in acute hepatitis C virus infection. Viruses. 4: 581-612. PMID 22590687 DOI: 10.3390/V4040581 |
0.416 |
|
| 2012 |
Brennan BJ, Morcos PN, Wang K, Blotner SD, Morrison R, Hagedorn CH, Marbury TC, Sulkowski M, Grippo JF. The pharmacokinetics of peginterferon alfa-2a and ribavirin in African American, Hispanic and Caucasian patients with chronic hepatitis C. Alimentary Pharmacology & Therapeutics. 35: 1209-20. PMID 22469033 DOI: 10.1111/J.1365-2036.2012.05079.X |
0.317 |
|
| 2012 |
Roy A, Wang C, Li C, Lu L, Torbenson M, Hagedorn CH, Schwarz KB. Phenotypic and genotypic differences between a child with vertically acquired severe hepatitis C liver disease and his mother. Journal of Pediatric Gastroenterology and Nutrition. 54: 567-9. PMID 21716134 DOI: 10.1097/Mpg.0B013E318229D96F |
0.338 |
|
| 2012 |
Krishnamurthy C, Hagedorn CH, Delker D, Clayton F, Vinson LA, Nelson C, Peterson K. Su1119 Next Generation Sequencing of RNA Polymerase II Transcripts Identifies Novel Genes Involved in the Pathogenesis of Eosinophilic Esophagitis (EoE) Gastroenterology. 142. DOI: 10.1016/S0016-5085(12)61617-5 |
0.304 |
|
| 2011 |
Folkers ME, Delker DA, Maxwell CI, Nelson CA, Schwartz JJ, Nix DA, Hagedorn CH. ENCODE tiling array analysis identifies differentially expressed annotated and novel 5' capped RNAs in hepatitis C infected liver. Plos One. 6: e14697. PMID 21359205 DOI: 10.1371/Journal.Pone.0014697 |
0.409 |
|
| 2011 |
Liu S, Nelson CA, Xiao L, Lu L, Seth PP, Davis DR, Hagedorn CH. Measuring antiviral activity of benzimidazole molecules that alter IRES RNA structure with an infectious hepatitis C virus chimera expressing Renilla luciferase. Antiviral Research. 89: 54-63. PMID 21075143 DOI: 10.1016/J.Antiviral.2010.11.004 |
0.393 |
|
| 2011 |
Zhang Y, Hagedorn CH, Wang L. Role of nuclear receptor SHP in metabolism and cancer. Biochimica Et Biophysica Acta. 1812: 893-908. PMID 20970497 DOI: 10.1016/J.Bbadis.2010.10.006 |
0.302 |
|
| 2010 |
Harrus D, Ahmed-El-Sayed N, Simister PC, Miller S, Triconnet M, Hagedorn CH, Mahias K, Rey FA, Astier-Gin T, Bressanelli S. Further insights into the roles of GTP and the C terminus of the hepatitis C virus polymerase in the initiation of RNA synthesis. The Journal of Biological Chemistry. 285: 32906-18. PMID 20729191 DOI: 10.1074/Jbc.M110.151316 |
0.363 |
|
| 2010 |
Gowda M, Nunes CC, Sailsbery J, Xue M, Chen F, Nelson CA, Brown DE, Oh Y, Meng S, Mitchell T, Hagedorn CH, Dean RA. Genome-wide characterization of methylguanosine-capped and polyadenylated small RNAs in the rice blast fungus Magnaporthe oryzae. Nucleic Acids Research. 38: 7558-69. PMID 20660015 DOI: 10.1093/Nar/Gkq583 |
0.323 |
|
| 2010 |
Folkers ME, Delker D, Maxwell CI, Nelson CA, Nix DA, Hagedorn CH. T1999 Gene Expression Changes in Hepatitis C Infected Liver as Measured by Encode Tiling Array Analysis of Both 5′ CAP and 3′ poly(A) RNA Gastroenterology. 138. DOI: 10.1016/S0016-5085(10)63895-4 |
0.34 |
|
| 2010 |
Liu S, Nelson CA, Lu L, Davis D, Hagedorn CH. 474 Development of a High Titer Infectious Renilla Luciferase Reporter HCV and use in Testing Antiviral Activity of Novel Small Molecules That Bind the HCV IRES Gastroenterology. 138: S-788. DOI: 10.1016/S0016-5085(10)63632-3 |
0.339 |
|
| 2010 |
Maxwell CI, Delker D, Liu S, Nelson CA, Nix DA, Folkers ME, Hagedorn CH. 473 RNA-Sequencing Analysis of 5′ Capped RNA in HCV Infected Cirrhotic Liver, Acutely HCV Infected Huh 7.5 Cells, and Control Specimens Identifies Common Upregulated Known and Novel Genes Gastroenterology. 138. DOI: 10.1016/S0016-5085(10)63631-1 |
0.395 |
|
| 2009 |
Roy A, Wang C, Li C, Lu L, Hagedorn CH, Schwarz KB. 826 Phenotypic and Genotypic Differences in a Child with Vertically-Acquired Severe HCV Liver Disease and His Mother Gastroenterology. 136. DOI: 10.1016/S0016-5085(09)63729-X |
0.323 |
|
| 2008 |
Xia X, Lu L, Tee KK, Zhao W, Wu J, Yu J, Li X, Lin Y, Mukhtar MM, Hagedorn CH, Takebe Y. The unique HCV genotype distribution and the discovery of a novel subtype 6u among IDUs co-infected with HIV-1 in Yunnan, China. Journal of Medical Virology. 80: 1142-52. PMID 18461611 DOI: 10.1002/Jmv.21204 |
0.335 |
|
| 2008 |
Bajak EZ, Hagedorn CH. Efficient 5' cap-dependent RNA purification : use in identifying and studying subsets of RNA. Methods in Molecular Biology (Clifton, N.J.). 419: 147-60. PMID 18369981 DOI: 10.1007/978-1-59745-033-1_10 |
0.332 |
|
| 2008 |
Lu L, Murphy D, Li C, Liu S, Xia X, Pham PH, Jin Y, Hagedorn CH, Abe K. Complete genomes of three subtype 6t isolates and analysis of many novel hepatitis C virus variants within genotype 6. The Journal of General Virology. 89: 444-52. PMID 18198375 DOI: 10.1099/Vir.0.83460-0 |
0.314 |
|
| 2007 |
Lu L, Li C, Fu Y, Gao F, Pybus OG, Abe K, Okamoto H, Hagedorn CH, Murphy D. Complete genomes of hepatitis C virus (HCV) subtypes 6c, 6l, 6o, 6p and 6q: completion of a full panel of genomes for HCV genotype 6. The Journal of General Virology. 88: 1519-25. PMID 17412981 DOI: 10.1099/Vir.0.82820-0 |
0.351 |
|
| 2007 |
Lu L, Li C, Fu Y, Thaikruea L, Thongswat S, Maneekarn N, Apichartpiyakul C, Hotta H, Okamoto H, Netski D, Pybus OG, Murphy D, Hagedorn CH, Nelson KE. Complete genomes for hepatitis C virus subtypes 6f, 6i, 6j and 6m: viral genetic diversity among Thai blood donors and infected spouses. The Journal of General Virology. 88: 1505-18. PMID 17412980 DOI: 10.1099/Vir.0.82604-0 |
0.352 |
|
| 2007 |
Goldson TM, Vielhauer G, Staub E, Miller S, Shim H, Hagedorn CH. Eukaryotic initiation factor 4E variants alter the morphology, proliferation, and colony-formation properties of MDA-MB-435 cancer cells. Molecular Carcinogenesis. 46: 71-84. PMID 17091471 DOI: 10.1002/Mc.20276 |
0.683 |
|
| 2007 |
Sultana S, Hagedorn CH, Goss DJ. Biophysical Characterization of Mutant Hepatitis C Virus RNA Dependent RNA Polymerase The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A628-D |
0.322 |
|
| 2006 |
Loo YM, Owen DM, Li K, Erickson AK, Johnson CL, Fish PM, Carney DS, Wang T, Ishida H, Yoneyama M, Fujita T, Saito T, Lee WM, Hagedorn CH, Lau DT, et al. Viral and therapeutic control of IFN-beta promoter stimulator 1 during hepatitis C virus infection. Proceedings of the National Academy of Sciences of the United States of America. 103: 6001-6. PMID 16585524 DOI: 10.1073/Pnas.0601523103 |
0.371 |
|
| 2006 |
Lu L, Nakano T, Li C, Fu Y, Miller S, Kuiken C, Robertson BH, Hagedorn CH. Hepatitis C virus complete genome sequences identified from China representing subtypes 6k and 6n and a novel, as yet unassigned subtype within genotype 6. The Journal of General Virology. 87: 629-34. PMID 16476984 DOI: 10.1099/Vir.0.81400-0 |
0.352 |
|
| 2006 |
Lu L, Li C, Hagedorn CH. Phylogenetic analysis of global hepatitis E virus sequences: genetic diversity, subtypes and zoonosis. Reviews in Medical Virology. 16: 5-36. PMID 16175650 DOI: 10.1002/Rmv.482 |
0.303 |
|
| 2005 |
Schnabl B, Choi YH, Hagedorn CH, Bataller R. DNA microarrays and data mining to study hepatic fibrosis. Methods in Molecular Medicine. 117: 359-69. PMID 16118462 DOI: 10.1385/1-59259-940-0:359 |
0.335 |
|
| 2005 |
Bini EJ, Bräu N, Currie S, Shen H, Anand BS, Hu KQ, Jeffers L, Ho SB, Johnson D, Schmidt WN, King P, Cheung R, Morgan TR, Awad J, Pedrosa M, ... ... Hagedorn C, et al. Prospective multicenter study of eligibility for antiviral therapy among 4,084 U.S. veterans with chronic hepatitis C virus infection. The American Journal of Gastroenterology. 100: 1772-9. PMID 16086714 DOI: 10.1111/J.1572-0241.2005.41860.X |
0.342 |
|
| 2005 |
Weber M, Hagedorn CH, Harrison DG, Searles CD. Laminar shear stress and 3' polyadenylation of eNOS mRNA. Circulation Research. 96: 1161-8. PMID 15905462 DOI: 10.1161/01.Res.0000170651.72198.Fa |
0.32 |
|
| 2005 |
Lu L, Nakano T, Smallwood GA, Heffron TG, Robertson BH, Hagedorn CH. A refined long RT-PCR technique to amplify complete viral RNA genome sequences from clinical samples: application to a novel hepatitis C virus variant of genotype 6. Journal of Virological Methods. 126: 139-48. PMID 15847930 DOI: 10.1016/J.Jviromet.2005.01.031 |
0.379 |
|
| 2005 |
Lu L, Nakano T, He Y, Fu Y, Hagedorn CH, Robertson BH. Hepatitis C virus genotype distribution in China: predominance of closely related subtype 1b isolates and existence of new genotype 6 variants. Journal of Medical Virology. 75: 538-49. PMID 15714489 DOI: 10.1002/Jmv.20307 |
0.347 |
|
| 2003 |
Lou H, Choi YH, LaVoy JE, Major ME, Hagedorn CH. Analysis of mutant NS5B proteins encoded by isolates from chimpanzees chronically infected following clonal HCV RNA inoculation. Virology. 317: 65-72. PMID 14675625 DOI: 10.1016/J.Virol.2003.08.038 |
0.364 |
|
| 2003 |
Choi YH, Hagedorn CH. Purifying mRNAs with a high-affinity eIF4E mutant identifies the short 3' poly(A) end phenotype. Proceedings of the National Academy of Sciences of the United States of America. 100: 7033-8. PMID 12777618 DOI: 10.1073/Pnas.1232347100 |
0.309 |
|
| 2003 |
Schnabl B, Purbeck CA, Choi YH, Hagedorn CH, Brenner D. Replicative senescence of activated human hepatic stellate cells is accompanied by a pronounced inflammatory but less fibrogenic phenotype. Hepatology (Baltimore, Md.). 37: 653-64. PMID 12601363 DOI: 10.1053/Jhep.2003.50097 |
0.324 |
|
| 2003 |
Duncan RF, Peterson H, Hagedorn CH, Sevanian A. Oxidative stress increases eukaryotic initiation factor 4E phosphorylation in vascular cells. The Biochemical Journal. 369: 213-25. PMID 12215171 DOI: 10.1042/Bj20020435 |
0.312 |
|
| 2003 |
Lou H, LaVoy J, Choi YH, Mayor ME, Hagedorn CH. 303 Highh activity mutant of HCV NS5B polymerase identified in chronically infected chimpanzees Hepatology. 38: 301-301. DOI: 10.1016/S0270-9139(03)80346-4 |
0.346 |
|
| 2002 |
Spivak-Kroizman T, Friedland DE, De Staercke C, Gernert KM, Goss DJ, Hagedorn CH. Mutations in the S4-H2 loop of eIF4E which increase the affinity for m7GTP. Febs Letters. 516: 9-14. PMID 11959093 DOI: 10.1016/S0014-5793(02)02445-6 |
0.32 |
|
| 2002 |
Schnabl B, Choi YH, Olsen JC, Hagedorn CH, Brenner DA. Immortal activated human hepatic stellate cells generated by ectopic telomerase expression. Laboratory Investigation; a Journal of Technical Methods and Pathology. 82: 323-33. PMID 11896211 DOI: 10.1038/Labinvest.3780426 |
0.316 |
|
| 2000 |
Hagedorn CH, van Beers EH, De Staercke C. Hepatitis C virus RNA-dependent RNA polymerase (NS5B polymerase). Current Topics in Microbiology and Immunology. 242: 225-60. PMID 10592663 DOI: 10.1007/978-3-642-59605-6_11 |
0.381 |
|
| 1998 |
Al RH, Xie Y, Wang Y, Hagedorn CH. Expression of recombinant hepatitis C virus non-structural protein 5B in Escherichia coli. Virus Research. 53: 141-9. PMID 9620206 DOI: 10.1016/S0168-1702(97)00147-0 |
0.414 |
|
| 1997 |
Hagedorn CH, Spivak-Kroizman T, Friedland DE, Goss DJ, Xie Y. Expression of functional eIF-4Ehuman: purification, detailed characterization, and its use in isolating eIF-4E binding proteins. Protein Expression and Purification. 9: 53-60. PMID 9116502 DOI: 10.1006/Prep.1996.0661 |
0.336 |
|
| 1997 |
Friedland DE, Shoemaker MT, Xie Y, Wang Y, Hagedorn CH, Goss DJ. Identification of the cap binding domain of human recombinant eukaryotic protein synthesis initiation factor 4E using a photoaffinity analogue. Protein Science : a Publication of the Protein Society. 6: 125-31. PMID 9007984 DOI: 10.1002/Pro.5560060114 |
0.321 |
|
| 1997 |
Hagedorn C, Al R, Staercke CD, Wang Y, Xie Y. Characterization of recombinant hepatitis C virus NS5B gene product (RDRP) Antiviral Research. 34. DOI: 10.1016/S0166-3542(97)83325-6 |
0.316 |
|
| 1992 |
Robinson LC, Hubbard EJ, Graves PR, DePaoli-Roach AA, Roach PJ, Kung C, Haas DW, Hagedorn CH, Goebl M, Culbertson MR. Yeast casein kinase I homologues: an essential gene pair. Proceedings of the National Academy of Sciences of the United States of America. 89: 28-32. PMID 1729698 DOI: 10.1073/Pnas.89.1.28 |
0.301 |
|
| 1992 |
Bu X, Hagedorn CH. Phosphoprotein phosphatase 2A dephosphorylates eIF-4E and does not alter binding to the mRNA cap Febs Letters. 301: 15-18. PMID 1333409 DOI: 10.1016/0014-5793(92)80200-Z |
0.324 |
|
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