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Philipp E. Scherer - Publications

Affiliations: 
Yeshiva University, New York, NY, United States 
Area:
Molecular Biology, General Biophysics
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372 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Rosendo-Silva D, Gomes PB, Rodrigues T, Viana S, da Costa AN, Scherer PE, Reis F, Pereira F, Seiça R, Matafome P. Clinical and molecular profiling of human visceral adipose tissue reveals impairment of vascular architecture and remodeling as an early hallmark of dysfunction. Metabolism: Clinical and Experimental. 153: 155788. PMID 38219974 DOI: 10.1016/j.metabol.2024.155788  0.4
2023 Furber EC, Hyatt K, Collins K, Yu X, Droz BA, Holland A, Friedrich JL, Wojnicki S, Konkol DL, O'Farrell LS, Baker HE, Coskun T, Scherer PE, Kusminski CM, Christe ME, et al. GIPR Agonism Enhances TZD-Induced Insulin Sensitivity in Obese IR Mice. Diabetes. PMID 37934926 DOI: 10.2337/db23-0172  0.401
2023 Gliniak CM, Pedersen L, Scherer PE. Adipose tissue fibrosis: the unwanted houseguest invited by obesity. The Journal of Endocrinology. 259. PMID 37855264 DOI: 10.1530/JOE-23-0180  0.34
2023 Agarwal AK, Tunison K, Vale G, McDonald JG, Li X, Scherer PE, Horton JD, Garg A. Regulated adipose tissue-specific expression of human in lipodystrophic -null mice results in regeneration of adipose tissue. Iscience. 26: 107806. PMID 37752957 DOI: 10.1016/j.isci.2023.107806  0.347
2023 Brown KA, Scherer PE. Update on Adipose Tissue and Cancer. Endocrine Reviews. PMID 37260403 DOI: 10.1210/endrev/bnad015  0.339
2023 Sun K, Li X, Scherer PE. Extracellular Matrix (ECM) and Fibrosis in Adipose Tissue: Overview and Perspectives. Comprehensive Physiology. 13: 4387-4407. PMID 36715281 DOI: 10.1002/cphy.c220020  0.338
2022 Crewe C, Chen S, Bu D, Gliniak CM, Wernstedt Asterholm I, Yu XX, Joffin N, Oliveira de Souza C, Funcke JB, Oh DY, Varlamov O, Robino JJ, Gordillo R, Scherer PE. Deficient Caveolin-1 Synthesis in Adipocytes Stimulates Systemic Insulin-independent Glucose Uptake via Extracellular Vesicles. Diabetes. PMID 35880782 DOI: 10.2337/db22-0035  0.357
2021 Zhu Y, Li N, Huang M, Bartels M, Dogné S, Zhao S, Chen X, Crewe C, Straub L, Vishvanath L, Zhang Z, Shao M, Yang Y, Gliniak CM, Gordillo R, ... ... Scherer PE, et al. Adipose tissue hyaluronan production improves systemic glucose homeostasis and primes adipocytes for CL 316,243-stimulated lipolysis. Nature Communications. 12: 4829. PMID 34376643 DOI: 10.1038/s41467-021-25025-4  0.337
2021 Onodera T, Ghazvini Zadeh E, Xu P, Gordillo R, Guo Z, Joffin N, Yu B, Scherer PE, Li WH. PEGylated AdipoRon derivatives improve glucose and lipid metabolism under insulinopenic and high fat diet conditions. Journal of Lipid Research. 100095. PMID 34214600 DOI: 10.1016/j.jlr.2021.100095  0.329
2021 Li N, Zhao S, Zhang Z, Zhu Y, Gliniak CM, Vishvanath L, An YA, Wang MY, Deng Y, Zhu Q, Shan B, Sherwood A, Onodera T, Oz OK, Gordillo R, ... ... Scherer PE, et al. Adiponectin preserves metabolic fitness during aging. Elife. 10. PMID 33904399 DOI: 10.7554/eLife.65108  0.377
2021 Crewe C, Scherer PE. Intercellular and interorgan crosstalk through adipocyte extracellular vesicles. Reviews in Endocrine & Metabolic Disorders. PMID 33447986 DOI: 10.1007/s11154-020-09625-x  0.344
2020 Apostolopoulou M, Gordillo R, Gancheva S, Strassburger K, Herder C, Esposito I, Schlensak M, Scherer PE, Roden M. Role of ceramide-to-dihydroceramide ratios for insulin resistance and non-alcoholic fatty liver disease in humans. Bmj Open Diabetes Research & Care. 8. PMID 33219119 DOI: 10.1136/bmjdrc-2020-001860  0.305
2020 Kruglikov IL, Shah M, Scherer PE. Obesity and diabetes as comorbidities for COVID-19: Underlying mechanisms and the role of viral-bacterial interactions. Elife. 9. PMID 32930095 DOI: 10.7554/Elife.61330  0.357
2020 Zhang Z, Kruglikov I, Zhao S, Zi Z, Gliniak CM, Li N, Wang MY, Zhu Q, Kusminski CM, Scherer PE. Dermal adipocytes contribute to the metabolic regulation of dermal fibroblasts. Experimental Dermatology. PMID 32866299 DOI: 10.1111/Exd.14181  0.341
2020 Kruglikov IL, Joffin N, Scherer PE. The MMP14-caveolin axis and its potential relevance for lipoedema. Nature Reviews. Endocrinology. PMID 32792644 DOI: 10.1038/S41574-020-0395-Z  0.372
2020 Gliniak CM, Scherer PE. PHOSPHO1 puts the breaks on thermogenesis in brown adipocytes. Proceedings of the National Academy of Sciences of the United States of America. PMID 32641502 DOI: 10.1073/Pnas.2011052117  0.444
2020 Zhu Q, An YA, Kim M, Zhang Z, Zhao S, Zhu Y, Asterholm IW, Kusminski CM, Scherer PE. Suppressing Adipocyte Inflammation Promotes Insulin Resistance in Mice. Molecular Metabolism. 101010. PMID 32408016 DOI: 10.1016/J.Molmet.2020.101010  0.485
2020 Zhang Z, Gallagher T, Scherer PE, Beutler B. Tissue-specific disruption of uncovers adipocyte-intrinsic and -extrinsic features of the lipodystrophy syndrome. Proceedings of the National Academy of Sciences of the United States of America. PMID 32381739 DOI: 10.1073/Pnas.2000118117  0.477
2020 Kruglikov IL, Scherer PE. The role of adipocytes and adipocyte-like cells in the severity of COVID-19 infections. Obesity (Silver Spring, Md.). PMID 32339391 DOI: 10.1002/Oby.22856  0.358
2020 Zhao S, Kusminski CM, Elmquist JK, Scherer PE. Leptin: Less Is More. Diabetes. 69: 823-829. PMID 32312898 DOI: 10.2337/Dbi19-0018  0.397
2020 Zhao S, Li N, Zhu Y, Straub L, Zhang Z, Wang MY, Zhu Q, Kusminski CM, Elmquist JK, Scherer PE. Partial leptin deficiency confers resistance to diet-induced obesity in mice. Molecular Metabolism. 100995. PMID 32289482 DOI: 10.1016/J.Molmet.2020.100995  0.433
2020 Li X, Zhao Y, Chen C, Yang L, Lee HH, Wang Z, Zhang N, Kolonin MG, An Z, Ge X, Scherer PE, Sun K. The critical role of MMP14 in adipose tissue remodeling during obesity. Molecular and Cellular Biology. PMID 31988105 DOI: 10.1128/Mcb.00564-19  0.429
2019 Delitsikou V, Jarad G, Rajaram RD, Ino F, Rutkowski JM, Chen CD, Santos CXC, Scherer PE, Abraham CR, Shah AM, Feraille E, Miner JH, de Seigneux S. Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 31907991 DOI: 10.1096/Fj.201900893R  0.316
2019 Kusminski CM, Ghaben AL, Morley TS, Samms RJ, Adams AC, An Y, Johnson JA, Joffin N, Onodera T, Crewe C, Holland WL, Gordillo R, Scherer PE. A Novel Model of Diabetic Complications: Adipocyte Mitochondrial Dysfunction Triggers Massive β-Cell Hyperplasia. Diabetes. PMID 31882562 DOI: 10.2337/Db19-0327  0.446
2019 Frankl J, Sherwood A, Clegg DJ, Scherer PE, Öz OK. Imaging Metabolically Active Fat: A Literature Review and Mechanistic Insights. International Journal of Molecular Sciences. 20. PMID 31694216 DOI: 10.3390/Ijms20215509  0.344
2019 Song A, Dai W, Jang MJ, Medrano L, Li Z, Zhao H, Shao M, Tan J, Li A, Ning T, Miller MM, Armstrong B, Huss JM, Zhu Y, Liu Y, ... ... Scherer PE, et al. Low- and high-thermogenic brown adipocyte subpopulations coexist in murine adipose tissue. The Journal of Clinical Investigation. PMID 31573981 DOI: 10.1172/Jci129167  0.456
2019 Shao M, Wang QA, Song A, Vishvanath L, Busbuso NC, Scherer PE, Gupta RK. Cellular Origins of Beige Fat Cells Revisited. Diabetes. 68: 1874-1885. PMID 31540940 DOI: 10.2337/Db19-0308  0.388
2019 Wang QA, Scherer PE. Remodeling of Murine Mammary Adipose Tissue during Pregnancy, Lactation, and Involution. Journal of Mammary Gland Biology and Neoplasia. PMID 31512027 DOI: 10.1007/S10911-019-09434-2  0.376
2019 Zhang Z, Shao M, Hepler C, Zi Z, Zhao S, An YA, Zhu Y, Ghaben A, Wang MY, Li N, Onodera T, Joffin N, Crewe C, Zhu Q, Vishvanath L, ... ... Scherer PE, et al. Dermal adipose tissue has high plasticity and undergoes reversible dedifferentiation in mice. The Journal of Clinical Investigation. PMID 31503545 DOI: 10.1172/Jci130239  0.404
2019 Zhao S, Zhu Y, Schultz RD, Li N, He Z, Zhang Z, Caron A, Zhu Q, Sun K, Xiong W, Deng H, Sun J, Deng Y, Kim M, Lee CE, ... ... Scherer PE, et al. Partial Leptin Reduction as an Insulin Sensitization and Weight Loss Strategy. Cell Metabolism. PMID 31495688 DOI: 10.1016/J.Cmet.2019.08.005  0.429
2019 Stern JH, Smith G, Chen S, Unger R, Klein S, Scherer PE. Obesity dysregulates fasting-induced changes in glucagon secretion. The Journal of Endocrinology. PMID 31454790 DOI: 10.1530/Joe-19-0201  0.455
2019 Crewe C, Zhu Y, Paschoal VA, Joffin N, Ghaben AL, Gordillo R, Oh DY, Liang G, Horton JD, Scherer PE. SREBP-regulated adipocyte lipogenesis is dependent on substrate availability and redox modulation of mTORC1. Jci Insight. 5. PMID 31310592 DOI: 10.1172/Jci.Insight.129397  0.399
2019 Caron A, Reynolds RP, Castorena CM, Michael NJ, Lee CE, Lee S, Berdeaux R, Scherer PE, Elmquist JK. Adipocyte Gs but not Gi signaling regulates whole-body glucose homeostasis. Molecular Metabolism. PMID 31279640 DOI: 10.1016/J.Molmet.2019.06.019  0.409
2019 Funcke JB, Scherer PE. Beyond adiponectin and leptin: adipose tissue-derived mediators of inter-organ communication. Journal of Lipid Research. PMID 31209153 DOI: 10.1194/Jlr.R094060  0.406
2019 Gliniak CM, Scherer PE. Critical lipids link breastfeeding to healthy adipose tissue in infancy and adulthood. The Journal of Clinical Investigation. 130. PMID 31081800 DOI: 10.1172/Jci128830  0.368
2019 Chakraborty A, Barajas S, Lammoglia GM, Reyna AJ, Morley TS, Johnson JA, Scherer PE, Rutkowski JM. Vascular Endothelial Growth Factor-D (VEGF-D) Overexpression and Lymphatic Expansion in Murine Adipose Tissue Improves Metabolism in Obesity. The American Journal of Pathology. PMID 30878136 DOI: 10.1016/J.Ajpath.2018.12.008  0.47
2019 Ye R, Onodera T, Scherer PE. Lipotoxicity and Cell Maintenance in Obesity and Type 2 Diabetes. Journal of the Endocrine Society. 3: 617-631. PMID 30834357 DOI: 10.1210/Js.2018-00372  0.396
2019 Ye R, Onodera T, Blanchard PG, Kusminski CM, Esser V, Brekken RA, Scherer PE. β1 syntrophin supports autophagy initiation and protects against cerulein-induced acute pancreatitis. The American Journal of Pathology. PMID 30653956 DOI: 10.1016/J.Ajpath.2019.01.002  0.306
2019 Peri-Okonny PA, Baskin KK, Iwamoto G, Mitchell JH, Smith SA, Kim HK, Szweda LI, Bassel-Duby R, Fujikawa T, Castorena CM, Richardson J, Shelton JM, Ayers C, Berry JD, Malladi VS, ... ... Scherer PE, et al. High-Phosphate Diet Induces Exercise Intolerance and Impairs Fatty Acid Metabolism in Mice. Circulation. PMID 30612451 DOI: 10.1161/Circulationaha.118.037550  0.301
2019 Ghaben AL, Scherer PE. Adipogenesis and metabolic health. Nature Reviews. Molecular Cell Biology. PMID 30610207 DOI: 10.1038/S41580-018-0093-Z  0.421
2019 Scherer PE. The many secret lives of adipocytes: implications for diabetes. Diabetologia. 62: 223-232. PMID 30465066 DOI: 10.1007/S00125-018-4777-X  0.423
2019 Asterholm IW, Halberg N, Scherer PE. Mouse Models of Lipodystrophy Key reagents for the understanding of the metabolic syndrome. Drug Discovery Today. Disease Models. 4: 17-24. PMID 18193096 DOI: 10.1016/J.Ddmod.2007.10.003  0.443
2019 ZHU Q, SCHERER PE. 316-OR: Suppressing Adipose Tissue Inflammation Promotes Insulin Resistance in Mice Diabetes. 68: 316-OR. DOI: 10.2337/Db19-316-Or  0.502
2019 SONG A, JANG MJ, WU X, JIANG L, SCHERER PE, WANG Q. 315-OR: Two Brown Adipocyte Subpopulations with Distinct Thermogenic Activity Coexist and Undergo Dynamic Interconversions upon Changes in Environmental Temperature Diabetes. 68: 315-OR. DOI: 10.2337/Db19-315-Or  0.399
2019 YE R, SCHERER PE. 180-OR: Tissue-Specific Functions of PPARα Overexpression in Liver, Adipose, and Pancreatic ß Cells Diabetes. 68: 180-OR. DOI: 10.2337/Db19-180-Or  0.509
2019 ZHANG Z, SHAO M, GUPTA RK, SCHERER PE. 140-OR: Dermal Adipose Tissue—A Unique Fat Pad Undergoes Dynamic Changes by Reversible Dedifferentiation Diabetes. 68: 140-OR. DOI: 10.2337/Db19-140-Or  0.41
2019 Czysz A, Grannemann B, Mason B, Gadad B, Carmody T, Greer T, Scherer P, Trivedi M. T142. Insulin Resistance Impacts the Relationship of Depression Severity on Cognitive Control Biological Psychiatry. 85. DOI: 10.1016/J.Biopsych.2019.03.465  0.312
2018 Furman JL, Soyombo A, Czysz AH, Jha MK, Carmody TJ, Mason BL, Scherer PE, Trivedi MH. Adiponectin Moderates Antidepressant Treatment Outcome in the Combining Medications to Enhance Depression Outcomes Randomized Clinical Trial. Personalized Medicine in Psychiatry. 9: 1-7. PMID 30859144 DOI: 10.1016/J.Pmip.2018.05.001  0.307
2018 Kruglikov IL, Zhang Z, Scherer PE. The Role of Immature and Mature Adipocytes in Hair Cycling. Trends in Endocrinology and Metabolism: Tem. PMID 30558832 DOI: 10.1016/J.Tem.2018.11.004  0.374
2018 Joffin N, Scherer PE. Reduced oxygen consumption by fat cells improves metabolic defects. Nature. 564: 47-48. PMID 30510226 DOI: 10.1038/D41586-018-07248-6  0.372
2018 Crewe C, Joffin N, Rutkowski JM, Kim M, Zhang F, Towler DA, Gordillo R, Scherer PE. An Endothelial-to-Adipocyte Extracellular Vesicle Axis Governed by Metabolic State. Cell. PMID 30293865 DOI: 10.1016/J.Cell.2018.09.005  0.418
2018 Neeland IJ, Singh S, McGuire DK, Vega GL, Roddy T, Reilly DF, Castro-Perez J, Kozlitina J, Scherer PE. Relation of plasma ceramides to visceral adiposity, insulin resistance and the development of type 2 diabetes mellitus: the Dallas Heart Study. Diabetologia. PMID 30159588 DOI: 10.1007/S00125-018-4720-1  0.41
2018 Bagchi RA, Ferguson BS, Stratton MS, Hu T, Cavasin MA, Sun L, Lin YH, Liu D, Londono P, Song K, Pino MF, Sparks LM, Smith SR, Scherer PE, Collins S, et al. HDAC11 suppresses the thermogenic program of adipose tissue via BRD2. Jci Insight. 3. PMID 30089714 DOI: 10.1172/Jci.Insight.120159  0.449
2018 Cruz VH, Arner EN, Wynne KW, Scherer PE, Brekken RA. Loss of Tbk1 kinase activity protects mice from diet-induced metabolic dysfunction. Molecular Metabolism. PMID 29935921 DOI: 10.1016/J.Molmet.2018.06.007  0.405
2018 Wang QA, Song A, Chen W, Schwalie PC, Zhang F, Vishvanath L, Jiang L, Ye R, Shao M, Tao C, Gupta RK, Deplancke B, Scherer PE. Reversible De-differentiation of Mature White Adipocytes into Preadipocyte-like Precursors during Lactation. Cell Metabolism. PMID 29909970 DOI: 10.1016/J.Cmet.2018.05.022  0.33
2018 Wang X, Bi X, Zhang G, Deng Y, Luo X, Xu L, Scherer PE, Ferdous A, Fu G, Gillette TG, Lee AS, Jiang X, Wang ZV. Glucose-regulated protein 78 is essential for cardiac myocyte survival. Cell Death and Differentiation. PMID 29666470 DOI: 10.1038/S41418-018-0109-4  0.329
2018 Zhang Z, Zi Z, Lee EE, Zhao J, Contreras DC, South AP, Abel ED, Chong BF, Vandergriff T, Hosler GA, Scherer PE, Mettlen M, Rathmell JC, DeBerardinis RJ, Wang RC. Differential glucose requirement in skin homeostasis and injury identifies a therapeutic target for psoriasis. Nature Medicine. PMID 29662201 DOI: 10.1038/S41591-018-0003-0  0.362
2018 Apostolopoulou M, Gordillo R, Koliaki C, Gancheva S, Jelenik T, De Filippo E, Herder C, Markgraf D, Jankowiak F, Esposito I, Schlensak M, Scherer PE, Roden M. Specific Hepatic Sphingolipids Relate to Insulin Resistance, Oxidative Stress, and Inflammation in Nonalcoholic Steatohepatitis. Diabetes Care. PMID 29602794 DOI: 10.2337/Dc17-1318  0.442
2018 Deng Y, Wang ZV, Gordillo R, Zhu Y, Ali A, Zhang C, Wang X, Shao M, Zhang Z, Iyengar P, Gupta RK, Horton JD, Hill JA, Scherer PE. Adipocyte Xbp1s overexpression drives uridine production and reduces obesity. Molecular Metabolism. PMID 29551634 DOI: 10.1016/J.Molmet.2018.02.013  0.62
2018 Wang QA, Zhang F, Jiang L, Ye R, An Y, Shao M, Tao C, Gupta RK, Scherer PE. PPARγ and its Role in Adipocyte Homeostasis and Thiazolidinedione-Mediated Insulin Sensitization. Molecular and Cellular Biology. PMID 29483301 DOI: 10.1128/Mcb.00677-17  0.496
2018 Zhu Y, Kruglikov IL, Akgul Y, Scherer PE. Hyaluronan in adipogenesis, adipose tissue physiology and systemic metabolism. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 29458140 DOI: 10.1016/J.Matbio.2018.02.012  0.346
2018 Ye R, Gordillo R, Shao M, Onodera T, Chen Z, Chen S, Lin X, SoRelle JA, Li X, Tang M, Keller MP, Kuliawat R, Attie AD, Gupta RK, Holland WL, ... ... Scherer PE, et al. Intracellular lipid metabolism impairs β cell compensation during diet-induced obesity. The Journal of Clinical Investigation. PMID 29457786 DOI: 10.1172/Jci97702  0.456
2018 Zhang F, Hao G, Shao M, Nham K, An Y, Wang Q, Zhu Y, Kusminski CM, Hassan G, Gupta RK, Zhai Q, Sun X, Scherer PE, Oz OK. An Adipose Tissue Atlas: An Image-Guided Identification of Human-like BAT and Beige Depots in Rodents. Cell Metabolism. 27: 252-262.e3. PMID 29320705 DOI: 10.1016/J.Cmet.2017.12.004  0.36
2018 Zhang Z, Scherer PE. Adipose tissue: The dysfunctional adipocyte - a cancer cell's best friend. Nature Reviews. Endocrinology. PMID 29302078 DOI: 10.1038/Nrendo.2017.174  0.383
2018 KIM M, AN YA, BANG HS, SCHERER PE, PARK J. VEGF-A-Expressing Adipose Tissue Shows Rapid Beiging, Enhanced Survival after Transplantation Diabetes. 67: 279-LB. DOI: 10.2337/Db18-279-Lb  0.416
2018 GORDILLO R, ZHANG K, SCHERER PE, HAWKINS M. Thiazolidinediones’ Insulin-Sensitizing Properties Depend on Adiponectin-Mediated Reductions in Certain Ceramide Species Diabetes. 67: 277-LB. DOI: 10.2337/Db18-277-Lb  0.39
2018 AN YA, SCHERER PE. Targeting the Amyloid Precursor Protein (APP) to Mitochondria of White Adipose Tissues Triggers Mitochondrial Dysfunction and Obesity Diabetes. 67: 276-OR. DOI: 10.2337/Db18-276-Or  0.446
2018 STERN JH, SMITH GI, UNGER RH, KLEIN S, SCHERER PE. Fasting-Induced Changes in Glucagon Secretion Are Dysregulated in Obesity Diabetes. 67: 271-LB. DOI: 10.2337/Db18-271-Lb  0.357
2018 ZHAO S, SCHERER PE. TLR4-Induced Local Adipose Inflammation Critically Regulates Glucose Homeostasis Diabetes. 67: 2032-P. DOI: 10.2337/Db18-2032-P  0.501
2018 Zhang Z, Zi Z, Lee E, Zhao J, South A, Chong B, Vandergriff T, Hosler G, Scherer P, Mettlen M, Deberardinis R, Wang R. 639 Metabolic reprogramming maintains skin integrity in the absence of glucose transport and identifies a therapeutic vulnerability in psoriasiform hyperplasia Journal of Investigative Dermatology. 138: S109. DOI: 10.1016/J.Jid.2018.03.648  0.302
2017 Wilson RJ, Drake JC, Cui D, Zhang M, Perry HM, Kashatus JA, Kusminski CM, Scherer PE, Kashatus DF, Okusa MD, Yan Z. Conditional MitoTimer reporter mice for assessment of mitochondrial structure, oxidative stress, and mitophagy. Mitochondrion. PMID 29274400 DOI: 10.1016/J.Mito.2017.12.008  0.311
2017 Xia JY, Sun K, Hepler C, Ghaben AL, Gupta RK, An YA, Holland WL, Morley TS, Adams AC, Gordillo R, Kusminski CM, Scherer PE. Acute loss of adipose tissue-derived adiponectin triggers immediate metabolic deterioration in mice. Diabetologia. PMID 29224189 DOI: 10.1007/S00125-017-4516-8  0.4
2017 Zhu Q, Scherer PE. Immunologic and endocrine functions of adipose tissue: implications for kidney disease. Nature Reviews. Nephrology. PMID 29199276 DOI: 10.1038/Nrneph.2017.157  0.437
2017 Zhu Y, Zhao S, Deng Y, Gordillo R, Ghaben AL, Shao M, Zhang F, Xu P, Li Y, Cao H, Zagnitko O, Scott DA, Gupta RK, Xing C, Zhang BB, ... ... Scherer PE, et al. Hepatic GALE Regulates Whole Body Glucose Homeostasis by Modulating Tff3 Expression. Diabetes. PMID 28877911 DOI: 10.2337/Db17-0323  0.399
2017 Marangoni RG, Masui Y, Fang F, Korman B, Lord G, Lee J, Lakota K, Wei J, Scherer PE, Otvos L, Yamauchi T, Kubota N, Kadowaki T, Asano Y, Sato S, et al. Adiponectin is an endogenous anti-fibrotic mediator and therapeutic target. Scientific Reports. 7: 4397. PMID 28667272 DOI: 10.1038/S41598-017-04162-1  0.357
2017 Wang MY, Yu X, Lee Y, McCorkle SK, Chen S, Li J, Wang ZV, Davidson JA, Scherer PE, Holland WL, Unger RH, Roth MG. Dapagliflozin suppresses glucagon signaling in rodent models of diabetes. Proceedings of the National Academy of Sciences of the United States of America. PMID 28584109 DOI: 10.1073/Pnas.1705845114  0.381
2017 An YA, Sun K, Joffin N, Zhang F, Deng Y, Donzé O, Kusminski CM, Scherer PE. Angiopoietin-2 in white adipose tissue improves metabolic homeostasis through enhanced angiogenesis. Elife. 6. PMID 28355132 DOI: 10.7554/Elife.24071  0.423
2017 Holland WL, Scherer PE. Structural biology: Receptors grease the metabolic wheels. Nature. PMID 28329767 DOI: 10.1038/Nature21900  0.333
2017 Tao C, Holland WL, Wang QA, Shao M, Jia L, Sun K, Lin X, Kuo YC, Johnson JA, Gordillo R, Elmquist JK, Scherer PE. Short-Term vs. Long-Term Effects of Adipocyte Toll-like Receptor 4 Activation on Insulin Resistance in Male Mice. Endocrinology. PMID 28323977 DOI: 10.1210/En.2017-00024  0.479
2017 Deng Y, Wang ZV, Gordillo R, An Y, Zhang C, Liang Q, Yoshino J, Cautivo KM, De Brabander J, Elmquist JK, Horton JD, Hill JA, Klein S, Scherer PE. An adipo-biliary-uridine axis that regulates energy homeostasis. Science (New York, N.Y.). 355. PMID 28302796 DOI: 10.1126/Science.Aaf5375  0.352
2017 Holland WL, Xia JY, Johnson JA, Sun K, Pearson MJ, Sharma AX, Quittner-Strom E, Tippetts TS, Gordillo R, Scherer PE. Inducible overexpression of adiponectin receptors highlight the roles of adiponectin-induced ceramidase signaling in lipid and glucose homeostasis. Molecular Metabolism. 6: 267-275. PMID 28271033 DOI: 10.1016/J.Molmet.2017.01.002  0.415
2017 Park J, Kim M, Sun K, An YA, Gu X, Scherer PE. VEGF-A Expressing Adipose Tissue Shows Rapid Beiging, Enhanced Survival After Transplantation and Confers IL4-Independent Metabolic Improvements. Diabetes. PMID 28254844 DOI: 10.2337/Db16-1081  0.415
2017 Ghaben AL, Scherer PE. Pas de Deux: Glucagon and Thyroid Hormone Moving in Perfect Synchrony. Circulation Research. 120: 762-764. PMID 28254797 DOI: 10.1161/Circresaha.117.310452  0.426
2017 Crewe C, An YA, Scherer PE. The ominous triad of adipose tissue dysfunction: inflammation, fibrosis, and impaired angiogenesis. The Journal of Clinical Investigation. 127: 74-82. PMID 28045400 DOI: 10.1172/Jci88883  0.388
2017 An YA, Sun K, Joffin N, Zhang F, Deng Y, Donzé O, Kusminski CM, Scherer PE. Author response: Angiopoietin-2 in white adipose tissue improves metabolic homeostasis through enhanced angiogenesis Elife. DOI: 10.7554/Elife.24071.024  0.372
2017 Stern J, Arriaga YE, Gupta A, Verma U, Karri S, Syed SK, Khosama L, Mansour JC, Scherer P, Beg MS. The effects of pioglitazone treatment on pancreatic cancer-related insulin resistance. Journal of Clinical Oncology. 35: 329-329. DOI: 10.1200/Jco.2017.35.4_Suppl.329  0.41
2017 Scherer PE. Abstract SY28-01: Stromal contributions of adipocytes to cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Sy28-01  0.445
2016 Dufurrena Q, Amjad FM, Scherer PE, Weiss LM, Nagajyothi J, Roth J, Tanowitz HB, Kuliawat R. Alterations in pancreatic β cell function and Trypanosoma cruzi infection: evidence from human and animal studies. Parasitology Research. PMID 28013375 DOI: 10.1007/S00436-016-5350-5  0.359
2016 Tanowitz HB, Scherer PE, Mota MM, Figueiredo LM. Adipose Tissue: A Safe Haven for Parasites? Trends in Parasitology. PMID 28007406 DOI: 10.1016/J.Pt.2016.11.008  0.309
2016 Lu Z, Xie J, Wu G, Shen J, Collins R, Chen W, Kang X, Luo M, Zou Y, Huang LJ, Amatruda JF, Slone T, Winick N, Scherer PE, Zhang CC. Fasting selectively blocks development of acute lymphoblastic leukemia via leptin-receptor upregulation. Nature Medicine. PMID 27941793 DOI: 10.1038/Nm.4252  0.306
2016 Sanada Y, Yamamoto T, Satake R, Yamashita A, Kanai S, Kato N, van de Loo FA, Nishimura F, Scherer PE, Yanaka N. Serum Amyloid A3 Gene Expression in Adipocytes is an Indicator of the Interaction with Macrophages. Scientific Reports. 6: 38697. PMID 27929048 DOI: 10.1038/Srep38697  0.406
2016 Rutkowski JM, Pastor J, Sun K, Park SK, Bobulescu IA, Chen CT, Moe OW, Scherer PE. Adiponectin alters renal calcium and phosphate excretion through regulation of klotho expression. Kidney International. PMID 27914707 DOI: 10.1016/J.Kint.2016.09.016  0.349
2016 Jun JC, Devera R, Unnikrishnan D, Shin MK, Bevans-Fonti S, Yao Q, Rathore A, Younas H, Halberg N, Scherer PE, Polotsky VY. Adipose HIF-1α causes obesity by suppressing brown adipose tissue thermogenesis. Journal of Molecular Medicine (Berlin, Germany). PMID 27738746 DOI: 10.1007/S00109-016-1480-6  0.366
2016 Sun K, Park J, Kim M, Scherer PE. Endotrophin, a multifaceted player in metabolic dysregulation and cancer progression, is a predictive biomarker for the response to PPARγ agonist treatment. Diabetologia. PMID 27717959 DOI: 10.1007/S00125-016-4130-1  0.414
2016 Sun J, Gao Y, Yao T, Huang Y, He Z, Kong X, Yu KJ, Wang RT, Guo H, Yan J, Chang Y, Chen H, Scherer PE, Liu T, Williams KW. Adiponectin potentiates the acute effects of leptin in arcuate Pomc neurons. Molecular Metabolism. 5: 882-91. PMID 27689001 DOI: 10.1016/J.Molmet.2016.08.007  0.331
2016 Gehrand AL, Hoeynck B, Jablonski M, Leonovicz C, Ye R, Scherer PE, Raff H. Sex differences in adult rat insulin and glucose responses to arginine: programming effects of neonatal separation, hypoxia, and hypothermia. Physiological Reports. 4. PMID 27664190 DOI: 10.14814/Phy2.12972  0.349
2016 Zhu Y, Gao Y, Tao C, Shao M, Zhao S, Huang W, Yao T, Johnson JA, Liu T, Cypess AM, Gupta O, Holland WL, Gupta RK, Spray DC, Tanowitz HB, ... ... Scherer PE, et al. Connexin 43 Mediates White Adipose Tissue Beiging by Facilitating the Propagation of Sympathetic Neuronal Signals. Cell Metabolism. 24: 420-433. PMID 27626200 DOI: 10.1016/J.Cmet.2016.08.005  0.373
2016 Turer AT, Scherer PE. Adiponectin: Just Along for the Ride? Circulation Research. 119: 407-8. PMID 27458194 DOI: 10.1161/Circresaha.116.309226  0.473
2016 Peri-Okonny PA, Ayers C, Maalouf N, Das SR, de Lemos JA, Berry JD, Turer AT, Neeland IJ, Scherer PE, Vongpatanasin W. Adiponectin predicts incident hypertension independent of body fat distribution: observations from the Dallas Heart Study. Diabetes/Metabolism Research and Reviews. PMID 27455039 DOI: 10.1002/Dmrr.2840  0.447
2016 Asterholm IW, Kim-Muller JY, Rutkowski JM, Crewe C, Tao C, Scherer PE. Pathological Type-2 Immune Response, Enhanced Tumor Growth, and Glucose Intolerance in Retnla Null Mice: A Model of Intestinal Immune System Dysfunction in Disease Susceptibility. The American Journal of Pathology. PMID 27397737 DOI: 10.1016/J.Ajpath.2016.04.017  0.364
2016 Han YH, Buffolo M, Pires KM, Pei S, Scherer PE, Boudina S. Adipocyte-Specific Deletion of Manganese Superoxide Dismutase Protects from Diet-Induced Obesity Via Increased Mitochondrial Uncoupling and Biogenesis. Diabetes. PMID 27284109 DOI: 10.2337/Db16-0283  0.443
2016 Kusminski CM, Bickel PE, Scherer PE. Targeting adipose tissue in the treatment of obesity-associated diabetes. Nature Reviews. Drug Discovery. PMID 27256476 DOI: 10.1038/Nrd.2016.75  0.471
2016 Scherer PE, Hill JA. Obesity, Diabetes, and Cardiovascular Diseases: A Compendium. Circulation Research. 118: 1703-5. PMID 27230636 DOI: 10.1161/Circresaha.116.308999  0.327
2016 Scherer PE. The Multifaceted Roles of Adipose Tissue-Therapeutic Targets for Diabetes and Beyond: The 2015 Banting Lecture. Diabetes. 65: 1452-61. PMID 27222389 DOI: 10.2337/Db16-0339  0.441
2016 Stern JH, Rutkowski JM, Scherer PE. Adiponectin, Leptin, and Fatty Acids in the Maintenance of Metabolic Homeostasis through Adipose Tissue Crosstalk. Cell Metabolism. 23: 770-84. PMID 27166942 DOI: 10.1016/J.Cmet.2016.04.011  0.386
2016 Wang QA, Scherer PE. Human Beige Adipocytes: Epiphenomenon or Drivers of Metabolic Improvements? Trends in Endocrinology and Metabolism: Tem. PMID 27040112 DOI: 10.1016/J.Tem.2016.03.008  0.317
2016 Tan CY, Virtue S, Murfitt S, Roberts LD, Phua YH, Dale M, Griffin JL, Tinahones F, Scherer PE, Vidal-Puig A. Erratum: Adipose tissue fatty acid chain length and mono-unsaturation increases with obesity and insulin resistance. Scientific Reports. 6: 23873. PMID 27027977 DOI: 10.1038/Srep23873  0.431
2016 Wang ZV, Scherer PE. Adiponectin, the past two decades. Journal of Molecular Cell Biology. PMID 26993047 DOI: 10.1093/Jmcb/Mjw011  0.445
2016 Iyengar P, Scherer PE. Obesity: Slim without the gym - the magic of chilling out. Nature Reviews. Endocrinology. 12: 252-4. PMID 26915527 DOI: 10.1038/Nrendo.2016.20  0.572
2016 Kruglikov IL, Scherer PE, Wollina U. Are dermal adipocytes involved in psoriasis? Experimental Dermatology. PMID 26913468 DOI: 10.1111/Exd.12996  0.382
2016 Kusminski CM, Chen S, Ye R, Sun K, Wang QA, Spurgin SB, Sanders PE, Brozinick JT, Li WH, Unger RH, Scherer PE. MitoNEET-Parkin Effects in Pancreatic α- and β-Cells, Cellular Survival and Intra-Insular Crosstalk. Diabetes. PMID 26895793 DOI: 10.2337/Db15-1323  0.335
2016 Senol-Cosar O, Flach RJ, DiStefano M, Chawla A, Nicoloro S, Straubhaar J, Hardy OT, Noh HL, Kim JK, Wabitsch M, Scherer PE, Czech MP. Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion. Nature Communications. 7: 10686. PMID 26880110 DOI: 10.1038/Ncomms10686  0.526
2016 Zhu Y, Crewe C, Scherer PE. Hyaluronan in adipose tissue: Beyond dermal filler and therapeutic carrier. Science Translational Medicine. 8: 323ps4. PMID 26819194 DOI: 10.1126/Scitranslmed.Aad6793  0.405
2016 Kruglikov IL, Scherer PE. Dermal adipocytes and hair cycling: is spatial heterogeneity a characteristic feature of the dermal adipose tissue depot? Experimental Dermatology. 25: 258-62. PMID 26781768 DOI: 10.1111/Exd.12941  0.319
2016 Davidson JA, Holland WL, Roth MG, Wang MY, Lee Y, Yu X, McCorkle SK, Scherer PE, Unger RH. Glucagon therapeutics, dawn of a new era for diabetes care. Diabetes/Metabolism Research and Reviews. PMID 26729301 DOI: 10.1002/Dmrr.2773  0.381
2016 Valero-Muñoz M, Li S, Wilson RM, Hulsmans M, Aprahamian T, Fuster JJ, Nahrendorf M, Scherer PE, Sam F. Heart Failure With Preserved Ejection Fraction Induces Beiging in Adipose Tissue. Circulation. Heart Failure. 9: e002724. PMID 26721917 DOI: 10.1161/Circheartfailure.115.002724  0.4
2016 Kursawe R, Dixit VD, Scherer PE, Santoro N, Narayan D, Gordillo R, Giannini C, Lopez X, Pierpont B, Nouws J, Shulman GI, Caprio S. A Role of the Inflammasome in the Low Storage Capacity of the Abdominal Subcutaneous Adipose Tissue in Obese Adolescents. Diabetes. 65: 610-8. PMID 26718495 DOI: 10.2337/Db15-1478  0.446
2016 Kruglikov IL, Scherer PE. Dermal Adipocytes: From Irrelevance to Metabolic Targets? Trends in Endocrinology and Metabolism: Tem. 27: 1-10. PMID 26643658 DOI: 10.1016/J.Tem.2015.11.002  0.365
2016 Peri-Okonny PA, Ayers CR, Maalouf N, Das SR, de Lemos JA, Berry J, Turer A, Neeland IJ, Scherer PE, Vongpatanasin W. Adiponectin predicts incident hypertension independent of body fat accumulation; observations from the dallas heart study Journal of the American Society of Hypertension. 10: e67. DOI: 10.1016/J.Jash.2016.03.164  0.304
2015 Yew Tan C, Virtue S, Murfitt S, Robert LD, Phua YH, Dale M, Griffin JL, Tinahones F, Scherer PE, Vidal-Puig A. Adipose tissue fatty acid chain length and mono-unsaturation increases with obesity and insulin resistance. Scientific Reports. 5: 18366. PMID 26679101 DOI: 10.1038/Srep18366  0.464
2015 Ye R, Wang QA, Tao C, Vishvanath L, Shao M, McDonald JG, Gupta RK, Scherer PE. Impact of tamoxifen on adipocyte lineage tracing: Inducer of adipogenesis and prolonged nuclear translocation of Cre recombinase. Molecular Metabolism. 4: 771-778. PMID 26629402 DOI: 10.1016/J.Molmet.2015.08.004  0.378
2015 Kusminski CM, Gallardo-Montejano VI, Wang ZV, Hegde V, Bickel PE, Dhurandhar NV, Scherer PE. E4orf1 induction in adipose tissue promotes insulin-independent signaling in the adipocyte. Molecular Metabolism. 4: 653-64. PMID 26500839 DOI: 10.1016/J.Molmet.2015.07.004  0.488
2015 Wang QA, Tao C, Jiang L, Shao M, Ye R, Zhu Y, Gordillo R, Ali A, Lian Y, Holland WL, Gupta RK, Scherer PE. Distinct regulatory mechanisms governing embryonic versus adult adipocyte maturation. Nature Cell Biology. 17: 1099-111. PMID 26280538 DOI: 10.1038/Ncb3217  0.37
2015 Morley TS, Xia JY, Scherer PE. Selective enhancement of insulin sensitivity in the mature adipocyte is sufficient for systemic metabolic improvements. Nature Communications. 6: 7906. PMID 26243466 DOI: 10.1038/Ncomms8906  0.513
2015 Stone KP, Wanders D, Calderon LF, Spurgin SB, Scherer PE, Gettys TW. Compromised responses to dietary methionine restriction in adipose tissue but not liver of ob/ob mice. Obesity (Silver Spring, Md.). 23: 1836-44. PMID 26237535 DOI: 10.1002/Oby.21177  0.511
2015 Xia JY, Holland WL, Kusminski CM, Sun K, Sharma AX, Pearson MJ, Sifuentes AJ, McDonald JG, Gordillo R, Scherer PE. Targeted Induction of Ceramide Degradation Leads to Improved Systemic Metabolism and Reduced Hepatic Steatosis. Cell Metabolism. 22: 266-278. PMID 26190650 DOI: 10.1016/J.Cmet.2015.06.007  0.453
2015 Combs TP, Snell-Bergeon JK, Maahs DM, Bergman BC, Lamarche M, Iberkleid L, AbdelBaky O, Tisch R, Scherer PE, Marliss EB. Adiponectin-SOGA Dissociation in Type 1 Diabetes. The Journal of Clinical Endocrinology and Metabolism. 100: E1065-73. PMID 26052615 DOI: 10.1210/Jc.2015-1275  0.313
2015 Warshauer JT, Lopez X, Gordillo R, Hicks J, Holland WL, Anuwe E, Blankfard MB, Scherer PE, Lingvay I. Effect of pioglitazone on plasma ceramides in adults with metabolic syndrome. Diabetes/Metabolism Research and Reviews. PMID 25959529 DOI: 10.1002/Dmrr.2662  0.418
2015 Kusminski CM, Scherer PE. Leptin beyond the lipostat: key component of blood pressure regulation. Circulation Research. 116: 1293-5. PMID 25858061 DOI: 10.1161/Circresaha.115.305937  0.423
2015 Ye R, Wang M, Wang QA, Scherer PE. Adiponectin-mediated antilipotoxic effects in regenerating pancreatic islets. Endocrinology. 156: 2019-28. PMID 25815422 DOI: 10.1210/En.2015-1066  0.374
2015 Rutkowski JM, Stern JH, Scherer PE. The cell biology of fat expansion. The Journal of Cell Biology. 208: 501-12. PMID 25733711 DOI: 10.1083/Jcb.201409063  0.436
2015 Burrill JS, Long EK, Reilly B, Deng Y, Armitage IM, Scherer PE, Bernlohr DA. Inflammation and ER stress regulate branched-chain amino acid uptake and metabolism in adipocytes. Molecular Endocrinology (Baltimore, Md.). 29: 411-20. PMID 25635940 DOI: 10.1210/Me.2014-1275  0.47
2015 Jin Z, Du Y, Schwaid AG, Asterholm IW, Scherer PE, Saghatelian A, Wan Y. Maternal adiponectin controls milk composition to prevent neonatal inflammation. Endocrinology. 156: 1504-13. PMID 25590242 DOI: 10.1210/En.2014-1738  0.335
2015 Stern JH, Scherer PE. Adipose tissue biology in 2014: Advances in our understanding of adipose tissue homeostasis. Nature Reviews. Endocrinology. 11: 71-2. PMID 25511312 DOI: 10.1038/Nrendo.2014.219  0.417
2015 Marangoni RG, Korman BD, Wei J, Wood TA, Graham LV, Whitfield ML, Scherer PE, Tourtellotte WG, Varga J. Myofibroblasts in murine cutaneous fibrosis originate from adiponectin-positive intradermal progenitors. Arthritis & Rheumatology (Hoboken, N.J.). 67: 1062-73. PMID 25504959 DOI: 10.1002/Art.38990  0.323
2015 de Seigneux S, Courbebaisse M, Rutkowski JM, Wilhelm-Bals A, Metzger M, Khodo SN, Hasler U, Chehade H, Dizin E, Daryadel A, Stengel B, Girardin E, Prié D, Wagner CA, ... Scherer PE, et al. Proteinuria Increases Plasma Phosphate by Altering Its Tubular Handling. Journal of the American Society of Nephrology : Jasn. 26: 1608-18. PMID 25349200 DOI: 10.1681/Asn.2014010104  0.309
2015 Hansen MT, Forst B, Cremers N, Quagliata L, Ambartsumian N, Grum-Schwensen B, Klingelhöfer J, Abdul-Al A, Herrmann P, Osterland M, Stein U, Nielsen GH, Scherer PE, Lukanidin E, Sleeman JP, et al. A link between inflammation and metastasis: serum amyloid A1 and A3 induce metastasis, and are targets of metastasis-inducing S100A4. Oncogene. 34: 424-35. PMID 24469032 DOI: 10.1038/Onc.2013.568  0.307
2015 Morley TS, Xia JY, Scherer PE. Selective enhancement of insulin sensitivity in the mature adipocyte is sufficient for systemic metabolic improvements Nature Communications. 6. DOI: 10.1038/ncomms8906  0.307
2014 Baskin KK, Grueter CE, Kusminski CM, Holland WL, Bookout AL, Satapati S, Kong YM, Burgess SC, Malloy CR, Scherer PE, Newgard CB, Bassel-Duby R, Olson EN. MED13-dependent signaling from the heart confers leanness by enhancing metabolism in adipose tissue and liver. Embo Molecular Medicine. 6: 1610-21. PMID 25422356 DOI: 10.15252/Emmm.201404218  0.36
2014 Ye R, Holland WL, Gordillo R, Wang M, Wang QA, Shao M, Morley TS, Gupta RK, Stahl A, Scherer PE. Adiponectin is essential for lipid homeostasis and survival under insulin deficiency and promotes β-cell regeneration. Elife. 3. PMID 25339419 DOI: 10.7554/Elife.03851  0.491
2014 Nagajyothi F, Weiss LM, Zhao D, Koba W, Jelicks LA, Cui MH, Factor SM, Scherer PE, Tanowitz HB. High fat diet modulates Trypanosoma cruzi infection associated myocarditis. Plos Neglected Tropical Diseases. 8: e3118. PMID 25275627 DOI: 10.1371/Journal.Pntd.0003118  0.356
2014 Kim M, Neinast MD, Frank AP, Sun K, Park J, Zehr JA, Vishvanath L, Morselli E, Amelotte M, Palmer BF, Gupta RK, Scherer PE, Clegg DJ. ERα upregulates Phd3 to ameliorate HIF-1 induced fibrosis and inflammation in adipose tissue. Molecular Metabolism. 3: 642-51. PMID 25161887 DOI: 10.1016/J.Molmet.2014.05.007  0.363
2014 Lee Y, Berglund ED, Yu X, Wang MY, Evans MR, Scherer PE, Holland WL, Charron MJ, Roth MG, Unger RH. Hyperglycemia in rodent models of type 2 diabetes requires insulin-resistant alpha cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 13217-22. PMID 25157166 DOI: 10.1073/Pnas.1409638111  0.46
2014 Burke S, Nagajyothi F, Thi MM, Hanani M, Scherer PE, Tanowitz HB, Spray DC. Adipocytes in both brown and white adipose tissue of adult mice are functionally connected via gap junctions: implications for Chagas disease. Microbes and Infection / Institut Pasteur. 16: 893-901. PMID 25150689 DOI: 10.1016/J.Micinf.2014.08.006  0.41
2014 Samocha-Bonet D, Dixit VD, Kahn CR, Leibel RL, Lin X, Nieuwdorp M, Pietiläinen KH, Rabasa-Lhoret R, Roden M, Scherer PE, Klein S, Ravussin E. Metabolically healthy and unhealthy obese--the 2013 Stock Conference report. Obesity Reviews : An Official Journal of the International Association For the Study of Obesity. 15: 697-708. PMID 25059108 DOI: 10.1111/Obr.12199  0.363
2014 Williams KW, Liu T, Kong X, Fukuda M, Deng Y, Berglund ED, Deng Z, Gao Y, Liu T, Sohn JW, Jia L, Fujikawa T, Kohno D, Scott MM, Lee S, ... ... Scherer PE, et al. Xbp1s in Pomc neurons connects ER stress with energy balance and glucose homeostasis. Cell Metabolism. 20: 471-82. PMID 25017942 DOI: 10.1016/J.Cmet.2014.06.002  0.443
2014 Wen JJ, Nagajyothi F, Machado FS, Weiss LM, Scherer PE, Tanowitz HB, Garg NJ. Markers of oxidative stress in adipose tissue during Trypanosoma cruzi infection. Parasitology Research. 113: 3159-65. PMID 24948102 DOI: 10.1007/S00436-014-3977-7  0.311
2014 Sun K, Kusminski CM, Luby-Phelps K, Spurgin SB, An YA, Wang QA, Holland WL, Scherer PE. Brown adipose tissue derived VEGF-A modulates cold tolerance and energy expenditure. Molecular Metabolism. 3: 474-83. PMID 24944907 DOI: 10.1016/J.Molmet.2014.03.010  0.412
2014 Ye R, Scherer PE. Fabp4, a new player in the adipo-pancreatic axis. Molecular Metabolism. 3: 347-8. PMID 24944893 DOI: 10.1016/J.Molmet.2014.03.009  0.491
2014 Park J, Morley TS, Kim M, Clegg DJ, Scherer PE. Obesity and cancer--mechanisms underlying tumour progression and recurrence. Nature Reviews. Endocrinology. 10: 455-65. PMID 24935119 DOI: 10.1038/Nrendo.2014.94  0.351
2014 Wernstedt Asterholm I, Tao C, Morley TS, Wang QA, Delgado-Lopez F, Wang ZV, Scherer PE. Adipocyte inflammation is essential for healthy adipose tissue expansion and remodeling. Cell Metabolism. 20: 103-18. PMID 24930973 DOI: 10.1016/J.Cmet.2014.05.005  0.826
2014 Berglund ED, Liu T, Kong X, Sohn JW, Vong L, Deng Z, Lee CE, Lee S, Williams KW, Olson DP, Scherer PE, Lowell BB, Elmquist JK. Melanocortin 4 receptors in autonomic neurons regulate thermogenesis and glycemia. Nature Neuroscience. 17: 911-3. PMID 24908101 DOI: 10.1038/Nn.3737  0.307
2014 Kusminski CM, Park J, Scherer PE. MitoNEET-mediated effects on browning of white adipose tissue. Nature Communications. 5: 3962. PMID 24865177 DOI: 10.1038/Ncomms4962  0.411
2014 Jia L, Vianna CR, Fukuda M, Berglund ED, Liu C, Tao C, Sun K, Liu T, Harper MJ, Lee CE, Lee S, Scherer PE, Elmquist JK. Hepatocyte Toll-like receptor 4 regulates obesity-induced inflammation and insulin resistance. Nature Communications. 5: 3878. PMID 24815961 DOI: 10.1038/Ncomms4878  0.483
2014 Liu M, Bai J, He S, Villarreal R, Hu D, Zhang C, Yang X, Liang H, Slaga TJ, Yu Y, Zhou Z, Blenis J, Scherer PE, Dong LQ, Liu F. Grb10 promotes lipolysis and thermogenesis by phosphorylation-dependent feedback inhibition of mTORC1. Cell Metabolism. 19: 967-80. PMID 24746805 DOI: 10.1016/J.Cmet.2014.03.018  0.476
2014 Wang QA, Scherer PE. The AdipoChaser mouse: A model tracking adipogenesis in vivo. Adipocyte. 3: 146-50. PMID 24719789 DOI: 10.4161/adip.27656  0.306
2014 Liu C, Bookout AL, Lee S, Sun K, Jia L, Lee C, Udit S, Deng Y, Scherer PE, Mangelsdorf DJ, Gautron L, Elmquist JK. PPARγ in vagal neurons regulates high-fat diet induced thermogenesis. Cell Metabolism. 19: 722-30. PMID 24703703 DOI: 10.1016/J.Cmet.2014.01.021  0.328
2014 Sun K, Park J, Gupta OT, Holland WL, Auerbach P, Zhang N, Goncalves Marangoni R, Nicoloro SM, Czech MP, Varga J, Ploug T, An Z, Scherer PE. Endotrophin triggers adipose tissue fibrosis and metabolic dysfunction. Nature Communications. 5: 3485. PMID 24647224 DOI: 10.1038/Ncomms4485  0.484
2014 Wang ZV, Deng Y, Gao N, Pedrozo Z, Li DL, Morales CR, Criollo A, Luo X, Tan W, Jiang N, Lehrman MA, Rothermel BA, Lee AH, Lavandero S, Mammen PPA, ... ... Scherer PE, et al. Spliced X-box binding protein 1 couples the unfolded protein response to hexosamine biosynthetic pathway Cell. 156: 1179-1192. PMID 24630721 DOI: 10.1016/J.Cell.2014.01.014  0.3
2014 Asterholm IW, Rutkowski JM, Fujikawa T, Cho YR, Fukuda M, Tao C, Wang ZV, Gupta RK, Elmquist JK, Scherer PE. Elevated resistin levels induce central leptin resistance and increased atherosclerotic progression in mice. Diabetologia. 57: 1209-18. PMID 24623101 DOI: 10.1007/S00125-014-3210-3  0.429
2014 Rutkowski JM, Halberg N, Wang QA, Holland WL, Xia JY, Scherer PE. Differential transendothelial transport of adiponectin complexes. Cardiovascular Diabetology. 13: 47. PMID 24552349 DOI: 10.1186/1475-2840-13-47  0.371
2014 Wang QA, Scherer PE, Gupta RK. Improved methodologies for the study of adipose biology: insights gained and opportunities ahead. Journal of Lipid Research. 55: 605-24. PMID 24532650 DOI: 10.1194/Jlr.R046441  0.351
2014 Rutkowski JM, Scherer PE. Isolation and quantitation of adiponectin higher order complexes. Methods in Enzymology. 537: 243-59. PMID 24480350 DOI: 10.1016/B978-0-12-411619-1.00013-6  0.433
2014 Bueno AC, Sun K, Martins CS, Elias Junior J, Miranda W, Tao C, Foss-Freitas MC, Barbieri MA, Bettiol H, de Castro M, Scherer PE, Antonini SR. A novel ADIPOQ mutation (p.M40K) impairs assembly of high-molecular-weight adiponectin and is associated with early-onset obesity and metabolic syndrome. The Journal of Clinical Endocrinology and Metabolism. 99: E683-93. PMID 24432991 DOI: 10.1210/Jc.2013-3009  0.311
2014 Zhu H, Guariglia S, Li W, Brancho D, Wang ZV, Scherer PE, Chow CW. Role of extracellular signal-regulated kinase 5 in adipocyte signaling. The Journal of Biological Chemistry. 289: 6311-22. PMID 24425864 DOI: 10.1074/Jbc.M113.506584  0.411
2014 Tso SC, Qi X, Gui WJ, Wu CY, Chuang JL, Wernstedt-Asterholm I, Morlock LK, Owens KR, Scherer PE, Williams NS, Tambar UK, Wynn RM, Chuang DT. Structure-guided development of specific pyruvate dehydrogenase kinase inhibitors targeting the ATP-binding pocket. The Journal of Biological Chemistry. 289: 4432-43. PMID 24356970 DOI: 10.1074/Jbc.M113.533885  0.383
2014 Pessa JE, Nguyen H, John GB, Scherer PE. The anatomical basis for wrinkles. Aesthetic Surgery Journal / the American Society For Aesthetic Plastic Surgery. 34: 227-34. PMID 24353247 DOI: 10.1177/1090820X13517896  0.318
2014 Lackey DE, Burk DH, Ali MR, Mostaedi R, Smith WH, Park J, Scherer PE, Seay SA, McCoin CS, Bonaldo P, Adams SH. Contributions of adipose tissue architectural and tensile properties toward defining healthy and unhealthy obesity. American Journal of Physiology. Endocrinology and Metabolism. 306: E233-46. PMID 24302007 DOI: 10.1152/Ajpendo.00476.2013  0.406
2014 Xia JY, Morley TS, Scherer PE. The adipokine/ceramide axis: key aspects of insulin sensitization. Biochimie. 96: 130-9. PMID 23969158 DOI: 10.1016/J.Biochi.2013.08.013  0.438
2014 Ye R, Holland WL, Gordillo R, Wang M, Wang QA, Shao M, Morley TS, Gupta RK, Stahl A, Scherer PE. Author response: Adiponectin is essential for lipid homeostasis and survival under insulin deficiency and promotes β-cell regeneration Elife. DOI: 10.7554/Elife.03851.039  0.382
2013 Holland WL, Scherer PE. Cell Biology. Ronning after the adiponectin receptors. Science (New York, N.Y.). 342: 1460-1. PMID 24357309 DOI: 10.1126/Science.1249077  0.394
2013 Unger RH, Scherer PE, Holland WL. Dichotomous roles of leptin and adiponectin as enforcers against lipotoxicity during feast and famine. Molecular Biology of the Cell. 24: 3011-5. PMID 24072813 DOI: 10.1091/Mbc.E12-10-0774  0.42
2013 Ye R, Scherer PE. Adiponectin, driver or passenger on the road to insulin sensitivity? Molecular Metabolism. 2: 133-41. PMID 24049728 DOI: 10.1016/J.Molmet.2013.04.001  0.415
2013 Wang QA, Tao C, Gupta RK, Scherer PE. Tracking adipogenesis during white adipose tissue development, expansion and regeneration. Nature Medicine. 19: 1338-44. PMID 23995282 DOI: 10.1038/Nm.3324  0.379
2013 Sun K, Tordjman J, Clément K, Scherer PE. Fibrosis and adipose tissue dysfunction. Cell Metabolism. 18: 470-7. PMID 23954640 DOI: 10.1016/J.Cmet.2013.06.016  0.4
2013 He C, Wei Y, Sun K, Li B, Dong X, Zou Z, Liu Y, Kinch LN, Khan S, Sinha S, Xavier RJ, Grishin NV, Xiao G, Eskelinen EL, Scherer PE, et al. Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism. Cell. 154: 1085-99. PMID 23954414 DOI: 10.1016/J.Cell.2013.07.035  0.374
2013 Giordano A, Murano I, Mondini E, Perugini J, Smorlesi A, Severi I, Barazzoni R, Scherer PE, Cinti S. Obese adipocytes show ultrastructural features of stressed cells and die of pyroptosis. Journal of Lipid Research. 54: 2423-36. PMID 23836106 DOI: 10.1194/Jlr.M038638  0.414
2013 Holland WL, Adams AC, Brozinick JT, Bui HH, Miyauchi Y, Kusminski CM, Bauer SM, Wade M, Singhal E, Cheng CC, Volk K, Kuo MS, Gordillo R, Kharitonenkov A, Scherer PE. An FGF21-adiponectin-ceramide axis controls energy expenditure and insulin action in mice. Cell Metabolism. 17: 790-7. PMID 23663742 DOI: 10.1016/J.Cmet.2013.03.019  0.497
2013 Park J, Morley TS, Scherer PE. Inhibition of endotrophin, a cleavage product of collagen VI, confers cisplatin sensitivity to tumours. Embo Molecular Medicine. 5: 935-48. PMID 23629957 DOI: 10.1002/Emmm.201202006  0.316
2013 Lopez X, Goldfine AB, Holland WL, Gordillo R, Scherer PE. Plasma ceramides are elevated in female children and adolescents with type 2 diabetes. Journal of Pediatric Endocrinology & Metabolism : Jpem. 26: 995-8. PMID 23612696 DOI: 10.1515/Jpem-2012-0407  0.388
2013 Wildman RP, Wang D, Fernandez I, Mancuso P, Santoro N, Scherer PE, Sowers MR. Associations of testosterone and sex hormone binding globulin with adipose tissue hormones in midlife women. Obesity (Silver Spring, Md.). 21: 629-36. PMID 23592672 DOI: 10.1002/Oby.20256  0.354
2013 Hefetz-Sela S, Scherer PE. Adipocytes: impact on tumor growth and potential sites for therapeutic intervention. Pharmacology & Therapeutics. 138: 197-210. PMID 23353703 DOI: 10.1016/J.Pharmthera.2013.01.008  0.401
2013 Keuper M, Wernstedt Asterholm I, Scherer PE, Westhoff MA, Möller P, Debatin KM, Strauss G, Wabitsch M, Fischer-Posovszky P. TRAIL (TNF-related apoptosis-inducing ligand) regulates adipocyte metabolism by caspase-mediated cleavage of PPARgamma. Cell Death & Disease. 4: e474. PMID 23348588 DOI: 10.1038/Cddis.2012.212  0.444
2013 Rutkowski JM, Wang ZV, Park AS, Zhang J, Zhang D, Hu MC, Moe OW, Susztak K, Scherer PE. Adiponectin promotes functional recovery after podocyte ablation. Journal of the American Society of Nephrology : Jasn. 24: 268-82. PMID 23334396 DOI: 10.1681/Asn.2012040414  0.321
2013 Nagajyothi F, Kuliawat R, Kusminski CM, Machado FS, Desruisseaux MS, Zhao D, Schwartz GJ, Huang H, Albanese C, Lisanti MP, Singh R, Li F, Weiss LM, Factor SM, Pessin JE, ... Scherer PE, et al. Alterations in glucose homeostasis in a murine model of Chagas disease. The American Journal of Pathology. 182: 886-94. PMID 23321322 DOI: 10.1016/J.Ajpath.2012.11.027  0.442
2013 Suk HY, Zhou C, Yang TT, Zhu H, Yu RY, Olabisi O, Yang X, Brancho D, Kim JY, Scherer PE, Frank PG, Lisanti MP, Calvert JW, Lefer DJ, Molkentin JD, et al. Ablation of calcineurin Aβ reveals hyperlipidemia and signaling cross-talks with phosphodiesterases. The Journal of Biological Chemistry. 288: 3477-88. PMID 23258544 DOI: 10.1074/Jbc.M112.419150  0.686
2013 Deng Y, Wang ZV, Tao C, Gao N, Holland WL, Ferdous A, Repa JJ, Liang G, Ye J, Lehrman MA, Hill JA, Horton JD, Scherer PE. The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism. The Journal of Clinical Investigation. 123: 455-68. PMID 23257357 DOI: 10.1172/Jci62819  0.383
2013 Sun K, Halberg N, Khan M, Magalang UJ, Scherer PE. Selective inhibition of hypoxia-inducible factor 1α ameliorates adipose tissue dysfunction. Molecular and Cellular Biology. 33: 904-17. PMID 23249949 DOI: 10.1128/Mcb.00951-12  0.45
2013 Murano I, Rutkowski JM, Wang QA, Cho YR, Scherer PE, Cinti S. Time course of histomorphological changes in adipose tissue upon acute lipoatrophy. Nutrition, Metabolism, and Cardiovascular Diseases : Nmcd. 23: 723-31. PMID 22682975 DOI: 10.1016/J.Numecd.2012.03.005  0.42
2012 Park J, Scherer PE. Endotrophin - a novel factor linking obesity with aggressive tumor growth. Oncotarget. 3: 1487-8. PMID 23455368 DOI: 10.18632/Oncotarget.796  0.417
2012 Turer AT, Hill JA, Elmquist JK, Scherer PE. Adipose tissue biology and cardiomyopathy: translational implications. Circulation Research. 111: 1565-77. PMID 23223931 DOI: 10.1161/Circresaha.111.262493  0.442
2012 Asterholm IW, Scherer PE. Metabolic jet lag when the fat clock is out of sync. Nature Medicine. 18: 1738-40. PMID 23223058 DOI: 10.1038/Nm.3010  0.358
2012 Park J, Scherer PE. Adipocyte-derived endotrophin promotes malignant tumor progression. The Journal of Clinical Investigation. 122: 4243-56. PMID 23041627 DOI: 10.1172/Jci63930  0.322
2012 Elmquist JK, Scherer PE. The cover. Neuroendocrine and endocrine pathways of obesity. Jama. 308: 1070-1. PMID 22990243 DOI: 10.1001/Jama.2012.3209  0.324
2012 Fraterrigo G, Fabbrini E, Mittendorfer B, O'Rahilly S, Scherer PE, Patterson BW, Klein S. Relationship between Changes in Plasma Adiponectin Concentration and Insulin Sensitivity after Niacin Therapy. Cardiorenal Medicine. 2: 211-217. PMID 22969777 DOI: 10.1159/000340037  0.461
2012 Kusminski CM, Holland WL, Sun K, Park J, Spurgin SB, Lin Y, Askew GR, Simcox JA, McClain DA, Li C, Scherer PE. MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity. Nature Medicine. 18: 1539-49. PMID 22961109 DOI: 10.1038/Nm.2899  0.409
2012 Liu M, Xiang R, Wilk SA, Zhang N, Sloane LB, Azarnoush K, Zhou L, Chen H, Xiang G, Walter CA, Austad SN, Musi N, DeFronzo RA, Asmis R, Scherer PE, et al. Fat-specific DsbA-L overexpression promotes adiponectin multimerization and protects mice from diet-induced obesity and insulin resistance. Diabetes. 61: 2776-86. PMID 22807031 DOI: 10.2337/Db12-0169  0.446
2012 Kusminski CM, Scherer PE. Mitochondrial dysfunction in white adipose tissue. Trends in Endocrinology and Metabolism: Tem. 23: 435-43. PMID 22784416 DOI: 10.1016/J.Tem.2012.06.004  0.422
2012 Liu J, Guo M, Zhang D, Cheng SY, Liu M, Ding J, Scherer PE, Liu F, Lu XY. Adiponectin is critical in determining susceptibility to depressive behaviors and has antidepressant-like activity. Proceedings of the National Academy of Sciences of the United States of America. 109: 12248-53. PMID 22778410 DOI: 10.1073/Pnas.1202835109  0.325
2012 Sun K, Scherer PE. The PPARγ-FGF1 axis: an unexpected mediator of adipose tissue homeostasis. Cell Research. 22: 1416-8. PMID 22710798 DOI: 10.1038/Cr.2012.94  0.465
2012 Turer AT, Scherer PE. Adiponectin: Mechanistic insights and clinical implications Diabetologia. 55: 2319-2326. PMID 22688349 DOI: 10.1007/S00125-012-2598-X  0.426
2012 Durand JL, Nawrocki AR, Scherer PE, Jelicks LA. Gender differences in adiponectin modulation of cardiac remodeling in mice deficient in endothelial nitric oxide synthase. Journal of Cellular Biochemistry. 113: 3276-87. PMID 22644792 DOI: 10.1002/Jcb.24206  0.339
2012 Ho GY, Wang T, Gunter MJ, Strickler HD, Cushman M, Kaplan RC, Wassertheil-Smoller S, Xue X, Rajpathak SN, Chlebowski RT, Vitolins MZ, Scherer PE, Rohan TE. Adipokines linking obesity with colorectal cancer risk in postmenopausal women. Cancer Research. 72: 3029-37. PMID 22511581 DOI: 10.1158/0008-5472.Can-11-2771  0.383
2012 Asterholm IW, McDonald J, Blanchard PG, Sinha M, Xiao Q, Mistry J, Rutkowski JM, Deshaies Y, Brekken RA, Scherer PE. Lack of "immunological fitness" during fasting in metabolically challenged animals. Journal of Lipid Research. 53: 1254-67. PMID 22504909 DOI: 10.1194/Jlr.M021725  0.444
2012 Sun K, Wernstedt Asterholm I, Kusminski CM, Bueno AC, Wang ZV, Pollard JW, Brekken RA, Scherer PE. Dichotomous effects of VEGF-A on adipose tissue dysfunction. Proceedings of the National Academy of Sciences of the United States of America. 109: 5874-9. PMID 22451920 DOI: 10.1073/Pnas.1200447109  0.488
2012 Turer AT, Browning JD, Ayers CR, Das SR, Khera A, Vega GL, Grundy SM, Scherer PE. Adiponectin as an independent predictor of the presence and degree of hepatic steatosis in the Dallas Heart Study. The Journal of Clinical Endocrinology and Metabolism. 97: E982-6. PMID 22438228 DOI: 10.1210/Jc.2011-3305  0.352
2012 Asterholm IW, Mundy DI, Weng J, Anderson RG, Scherer PE. Altered mitochondrial function and metabolic inflexibility associated with loss of caveolin-1. Cell Metabolism. 15: 171-85. PMID 22326219 DOI: 10.1016/J.Cmet.2012.01.004  0.416
2012 Nagajyothi F, Desruisseaux MS, Machado FS, Upadhya R, Zhao D, Schwartz GJ, Teixeira MM, Albanese C, Lisanti MP, Chua SC, Weiss LM, Scherer PE, Tanowitz HB. Response of adipose tissue to early infection with Trypanosoma cruzi (Brazil strain). The Journal of Infectious Diseases. 205: 830-40. PMID 22293433 DOI: 10.1093/Infdis/Jir840  0.394
2012 He C, Bassik MC, Moresi V, Sun K, Wei Y, Zou Z, An Z, Loh J, Fisher J, Sun Q, Korsmeyer S, Packer M, May HI, Hill JA, Virgin HW, ... ... Scherer PE, et al. Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis. Nature. 481: 511-5. PMID 22258505 DOI: 10.1038/Nature10758  0.342
2012 Shetty S, Ramos-Roman MA, Cho YR, Brown J, Plutzky J, Muise ES, Horton JD, Scherer PE, Parks EJ. Enhanced fatty acid flux triggered by adiponectin overexpression. Endocrinology. 153: 113-22. PMID 22045665 DOI: 10.1210/En.2011-1339  0.414
2011 Tanowitz HB, Jelicks LA, Machado FS, Esper L, Qi X, Desruisseaux MS, Chua SC, Scherer PE, Nagajyothi F. Adipose tissue, diabetes and Chagas disease. Advances in Parasitology. 76: 235-50. PMID 21884894 DOI: 10.1016/B978-0-12-385895-5.00010-4  0.434
2011 Turer AT, Khera A, Ayers CR, Turer CB, Grundy SM, Vega GL, Scherer PE. Adipose tissue mass and location affect circulating adiponectin levels. Diabetologia. 54: 2515-24. PMID 21779869 DOI: 10.1007/S00125-011-2252-Z  0.355
2011 Ferreira AV, Segatto M, Menezes Z, Macedo AM, Gelape C, de Oliveira Andrade L, Nagajyothi F, Scherer PE, Teixeira MM, Tanowitz HB. Evidence for Trypanosoma cruzi in adipose tissue in human chronic Chagas disease. Microbes and Infection. 13: 1002-5. PMID 21726660 DOI: 10.1016/J.Micinf.2011.06.002  0.335
2011 Fischer-Posovszky P, Wang QA, Asterholm IW, Rutkowski JM, Scherer PE. Targeted deletion of adipocytes by apoptosis leads to adipose tissue recruitment of alternatively activated M2 macrophages. Endocrinology. 152: 3074-81. PMID 21693678 DOI: 10.1210/En.2011-1031  0.385
2011 Park J, Scherer PE. Leptin and cancer: from cancer stem cells to metastasis. Endocrine-Related Cancer. 18: C25-9. PMID 21680729 DOI: 10.1530/Erc-11-0163  0.333
2011 Park J, Euhus DM, Scherer PE. Paracrine and endocrine effects of adipose tissue on cancer development and progression. Endocrine Reviews. 32: 550-70. PMID 21642230 DOI: 10.1210/Er.2010-0030  0.369
2011 Shafiei MS, Shetty S, Scherer PE, Rockey DC. Adiponectin regulation of stellate cell activation via PPARγ-dependent and -independent mechanisms. The American Journal of Pathology. 178: 2690-9. PMID 21641391 DOI: 10.1016/J.Ajpath.2011.02.035  0.328
2011 Sun K, Kusminski CM, Scherer PE. Adipose tissue remodeling and obesity Journal of Clinical Investigation. 121: 2094-2101. PMID 21633177 DOI: 10.1172/Jci45887  0.391
2011 Miller RA, Chu Q, Le Lay J, Scherer PE, Ahima RS, Kaestner KH, Foretz M, Viollet B, Birnbaum MJ. Adiponectin suppresses gluconeogenic gene expression in mouse hepatocytes independent of LKB1-AMPK signaling. The Journal of Clinical Investigation. 121: 2518-28. PMID 21606593 DOI: 10.1172/Jci45942  0.455
2011 Holland WL, Bikman BT, Wang LP, Yuguang G, Sargent KM, Bulchand S, Knotts TA, Shui G, Clegg DJ, Wenk MR, Pagliassotti MJ, Scherer PE, Summers SA. Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice. The Journal of Clinical Investigation. 121: 1858-70. PMID 21490391 DOI: 10.1172/Jci43378  0.44
2011 Holland WL, Miller RA, Wang ZV, Sun K, Barth BM, Bui HH, Davis KE, Bikman BT, Halberg N, Rutkowski JM, Wade MR, Tenorio VM, Kuo MS, Brozinick JT, Zhang BB, ... ... Scherer PE, et al. Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin. Nature Medicine. 17: 55-63. PMID 21186369 DOI: 10.1038/Nm.2277  0.393
2010 Deng Y, Scherer PE. Adipokines as novel biomarkers and regulators of the metabolic syndrome. Annals of the New York Academy of Sciences. 1212: E1-E19. PMID 21276002 DOI: 10.1111/J.1749-6632.2010.05875.X  0.414
2010 Park J, Kusminski CM, Chua SC, Scherer PE. Leptin receptor signaling supports cancer cell metabolism through suppression of mitochondrial respiration in vivo. The American Journal of Pathology. 177: 3133-44. PMID 21056997 DOI: 10.2353/Ajpath.2010.100595  0.406
2010 Xu Y, Berglund ED, Sohn JW, Holland WL, Chuang JC, Fukuda M, Rossi J, Williams KW, Jones JE, Zigman JM, Lowell BB, Scherer PE, Elmquist JK. 5-HT2CRs expressed by pro-opiomelanocortin neurons regulate insulin sensitivity in liver. Nature Neuroscience. 13: 1457-9. PMID 21037584 DOI: 10.1038/Nn.2664  0.301
2010 Nagajyothi F, Zhao D, Machado FS, Weiss LM, Schwartz GJ, Desruisseaux MS, Zhao Y, Factor SM, Huang H, Albanese C, Teixeira MM, Scherer PE, Chua SC, Tanowitz HB. Crucial role of the central leptin receptor in murine Trypanosoma cruzi (Brazil strain) infection. The Journal of Infectious Diseases. 202: 1104-13. PMID 20726767 DOI: 10.1086/656189  0.33
2010 Zhu H, Suk HY, Yu RY, Brancho D, Olabisi O, Yang TT, Yang X, Zhang J, Moussaif M, Durand JL, Jelicks LA, Kim JY, Scherer PE, Frank PG, Lisanti MP, et al. Evolutionarily conserved role of calcineurin in phosphodegron-dependent degradation of phosphodiesterase 4D. Molecular and Cellular Biology. 30: 4379-90. PMID 20647544 DOI: 10.1128/Mcb.01193-09  0.581
2010 Villasenor A, Wang ZV, Rivera LB, Ocal O, Asterholm IW, Scherer PE, Brekken RA, Cleaver O, Wilkie TM. Rgs16 and Rgs8 in embryonic endocrine pancreas and mouse models of diabetes Dmm Disease Models and Mechanisms. 3: 567-580. PMID 20616094 DOI: 10.1242/Dmm.003210  0.34
2010 Landskroner-Eiger S, Park J, Israel D, Pollard JW, Scherer PE. Morphogenesis of the developing mammary gland: stage-dependent impact of adipocytes. Developmental Biology. 344: 968-78. PMID 20599899 DOI: 10.1016/J.Ydbio.2010.06.019  0.811
2010 Vissapragada S, Ghosh A, Ringer L, Salinas P, Brophy A, Peaceman D, Kallakury B, Banerjee PP, Fricke ST, Helfrich W, Lee YC, Pestell R, Scherer P, Tanowitz HB, Avantaggiati ML, et al. Dietary n-3 polyunsaturated fatty acids fail to reduce prostate tumorigenesis in the PB-ErbB-2 x Pten(+/-) preclinical mouse model. Cell Cycle (Georgetown, Tex.). 9: 1824-9. PMID 20404514 DOI: 10.4161/Cc.9.9.11542  0.334
2010 Hill JW, Elias CF, Fukuda M, Williams KW, Berglund ED, Holland WL, Cho YR, Chuang JC, Xu Y, Choi M, Lauzon D, Lee CE, Coppari R, Richardson JA, Zigman JM, ... ... Scherer PE, et al. Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility. Cell Metabolism. 11: 286-97. PMID 20374961 DOI: 10.1016/J.Cmet.2010.03.002  0.443
2010 Kishore P, Li W, Tonelli J, Lee DE, Koppaka S, Zhang K, Lin Y, Kehlenbrink S, Scherer PE, Hawkins M. Adipocyte-derived factors potentiate nutrient-induced production of plasminogen activator inhibitor-1 by macrophages. Science Translational Medicine. 2: 20ra15. PMID 20371491 DOI: 10.1126/Scitranslmed.3000292  0.462
2010 Wang ZV, Deng Y, Wang QA, Sun K, Scherer PE. Identification and characterization of a promoter cassette conferring adipocyte-specific gene expression. Endocrinology. 151: 2933-9. PMID 20363877 DOI: 10.1210/En.2010-0136  0.365
2010 Nawrocki AR, Hofmann SM, Teupser D, Basford JE, Durand JL, Jelicks LA, Woo CW, Kuriakose G, Factor SM, Tanowitz HB, Hui DY, Tabas I, Scherer PE. Lack of association between adiponectin levels and atherosclerosis in mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 1159-65. PMID 20299691 DOI: 10.1161/Atvbaha.109.195826  0.408
2010 Unger RH, Scherer PE. Gluttony, sloth and the metabolic syndrome: a roadmap to lipotoxicity. Trends in Endocrinology and Metabolism: Tem. 21: 345-52. PMID 20223680 DOI: 10.1016/J.Tem.2010.01.009  0.348
2010 Asterholm IW, Scherer PE. Enhanced metabolic flexibility associated with elevated adiponectin levels. The American Journal of Pathology. 176: 1364-76. PMID 20093494 DOI: 10.2353/Ajpath.2010.090647  0.491
2010 Vernochet C, Davis KE, Scherer PE, Farmer SR. Mechanisms regulating repression of haptoglobin production by peroxisome proliferator-activated receptor-gamma ligands in adipocytes. Endocrinology. 151: 586-94. PMID 19952271 DOI: 10.1210/En.2009-1057  0.341
2009 Unger RH, Clark GO, Scherer PE, Orci L. Lipid homeostasis, lipotoxicity and the metabolic syndrome. Biochimica Et Biophysica Acta. 1801: 209-14. PMID 19948243 DOI: 10.1016/J.Bbalip.2009.10.006  0.381
2009 Khan T, Hamilton MP, Mundy DI, Chua SC, Scherer PE. Impact of simvastatin on adipose tissue: pleiotropic effects in vivo. Endocrinology. 150: 5262-72. PMID 19819942 DOI: 10.1210/En.2009-0603  0.825
2009 Rutkowski JM, Davis KE, Scherer PE. Mechanisms of obesity and related pathologies: the macro- and microcirculation of adipose tissue. The Febs Journal. 276: 5738-46. PMID 19754873 DOI: 10.1111/J.1742-4658.2009.07303.X  0.423
2009 Nagajyothi F, Desruisseaux MS, Weiss LM, Chua S, Albanese C, Machado FS, Esper L, Lisanti MP, Teixeira MM, Scherer PE, Tanowitz HB. Chagas disease, adipose tissue and the metabolic syndrome. MemóRias Do Instituto Oswaldo Cruz. 104: 219-25. PMID 19753477 DOI: 10.1590/S0074-02762009000900028  0.405
2009 Nagajyothi F, Desruisseaux MS, Jelicks LA, Machado FS, Chua S, Scherer PE, Tanowitz HB. Perspectives on adipose tissue, chagas disease and implications for the metabolic syndrome. Interdisciplinary Perspectives On Infectious Diseases. 2009: 824324. PMID 19644556 DOI: 10.1155/2009/824324  0.414
2009 Halberg N, Schraw TD, Wang ZV, Kim JY, Yi J, Hamilton MP, Luby-Phelps K, Scherer PE. Systemic fate of the adipocyte-derived factor adiponectin. Diabetes. 58: 1961-70. PMID 19581422 DOI: 10.2337/Db08-1750  0.67
2009 Rieck S, White P, Schug J, Fox AJ, Smirnova O, Gao N, Gupta RK, Wang ZV, Scherer PE, Keller MP, Attie AD, Kaestner KH. The transcriptional response of the islet to pregnancy in mice. Molecular Endocrinology (Baltimore, Md.). 23: 1702-12. PMID 19574445 DOI: 10.1210/Me.2009-0144  0.378
2009 Vernochet C, Peres SB, Davis KE, McDonald ME, Qiang L, Wang H, Scherer PE, Farmer SR. C/EBPalpha and the corepressors CtBP1 and CtBP2 regulate repression of select visceral white adipose genes during induction of the brown phenotype in white adipocytes by peroxisome proliferator-activated receptor gamma agonists. Molecular and Cellular Biology. 29: 4714-28. PMID 19564408 DOI: 10.1128/Mcb.01899-08  0.412
2009 Halberg N, Khan T, Trujillo ME, Wernstedt-Asterholm I, Attie AD, Sherwani S, Wang ZV, Landskroner-Eiger S, Dineen S, Magalang UJ, Brekken RA, Scherer PE. Hypoxia-inducible factor 1alpha induces fibrosis and insulin resistance in white adipose tissue. Molecular and Cellular Biology. 29: 4467-83. PMID 19546236 DOI: 10.1128/Mcb.00192-09  0.808
2009 Landskroner-Eiger S, Qian B, Muise ES, Nawrocki AR, Berger JP, Fine EJ, Koba W, Deng Y, Pollard JW, Scherer PE. Proangiogenic contribution of adiponectin toward mammary tumor growth in vivo. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 3265-76. PMID 19447867 DOI: 10.1158/1078-0432.Ccr-08-2649  0.773
2009 Kusminski CM, Shetty S, Orci L, Unger RH, Scherer PE. Diabetes and apoptosis: lipotoxicity. Apoptosis : An International Journal On Programmed Cell Death. 14: 1484-95. PMID 19421860 DOI: 10.1007/S10495-009-0352-8  0.46
2009 Shetty S, Kusminski CM, Scherer PE. Adiponectin in health and disease: evaluation of adiponectin-targeted drug development strategies. Trends in Pharmacological Sciences. 30: 234-9. PMID 19359049 DOI: 10.1016/J.Tips.2009.02.004  0.404
2009 Holland WL, Scherer PE. PAQRs: a counteracting force to ceramides? Molecular Pharmacology. 75: 740-3. PMID 19158359 DOI: 10.1124/Mol.109.054817  0.403
2009 Khan T, Muise ES, Iyengar P, Wang ZV, Chandalia M, Abate N, Zhang BB, Bonaldo P, Chua S, Scherer PE. Metabolic dysregulation and adipose tissue fibrosis: role of collagen VI. Molecular and Cellular Biology. 29: 1575-91. PMID 19114551 DOI: 10.1128/Mcb.01300-08  0.807
2009 Attie AD, Scherer PE. Adipocyte metabolism and obesity. Journal of Lipid Research. 50: S395-9. PMID 19017614 DOI: 10.1194/Jlr.R800057-Jlr200  0.475
2009 Li W, Tonelli J, Kishore P, Owen R, Goodman E, Scherer PE, Hawkins MA. Insulin-sensitizing effects of thiazolidinediones are not linked to adiponectin receptor expression in human fat or muscle (American Journal of Physiology - Endocrinology and Metabolism (E1301-E1307)) American Journal of Physiology-Endocrinology and Metabolism. 296. DOI: 10.1152/Ajpendo.Zh1-05575-Corr.2009  0.379
2008 Nagajyothi F, Desruisseaux MS, Thiruvur N, Weiss LM, Braunstein VL, Albanese C, Teixeira MM, de Almeida CJ, Lisanti MP, Scherer PE, Tanowitz HB. Trypanosoma cruzi infection of cultured adipocytes results in an inflammatory phenotype. Obesity (Silver Spring, Md.). 16: 1992-7. PMID 19186325 DOI: 10.1038/Oby.2008.331  0.374
2008 Wang ZV, Scherer PE. DsbA-L is a versatile player in adiponectin secretion. Proceedings of the National Academy of Sciences of the United States of America. 105: 18077-8. PMID 19020096 DOI: 10.1073/Pnas.0810027105  0.339
2008 Davis KE, Scherer PE. Adiponectin: no longer the lone soul in the fight against insulin resistance? The Biochemical Journal. 416: e7-9. PMID 18990088 DOI: 10.1042/Bj20082033  0.488
2008 Halberg N, Wernstedt-Asterholm I, Scherer PE. The adipocyte as an endocrine cell. Endocrinology and Metabolism Clinics of North America. 37: 753-68, x-xi. PMID 18775362 DOI: 10.1016/J.Ecl.2008.07.002  0.459
2008 Atzmon G, Pollin TI, Crandall J, Tanner K, Schechter CB, Scherer PE, Rincon M, Siegel G, Katz M, Lipton RB, Shuldiner AR, Barzilai N. Adiponectin levels and genotype: a potential regulator of life span in humans. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 63: 447-53. PMID 18511746 DOI: 10.1093/Gerona/63.5.447  0.336
2008 Wang ZV, Mu J, Schraw TD, Gautron L, Elmquist JK, Zhang BB, Brownlee M, Scherer PE. PANIC-ATTAC: a mouse model for inducible and reversible beta-cell ablation. Diabetes. 57: 2137-48. PMID 18469203 DOI: 10.2337/Db07-1631  0.305
2008 Dallaire P, Bellmann K, Laplante M, Gélinas S, Centeno-Baez C, Penfornis P, Peyot ML, Latour MG, Lamontagne J, Trujillo ME, Scherer PE, Prentki M, Deshaies Y, Marette A. Obese mice lacking inducible nitric oxide synthase are sensitized to the metabolic actions of peroxisome proliferator-activated receptor-gamma agonism. Diabetes. 57: 1999-2011. PMID 18458147 DOI: 10.2337/Db08-0540  0.406
2008 Schraw T, Wang ZV, Halberg N, Hawkins M, Scherer PE. Plasma adiponectin complexes have distinct biochemical characteristics. Endocrinology. 149: 2270-82. PMID 18202126 DOI: 10.1210/En.2007-1561  0.373
2008 Wildman RP, Mancuso P, Wang C, Kim M, Scherer PE, Sowers MR. Adipocytokine and ghrelin levels in relation to cardiovascular disease risk factors in women at midlife: Longitudinal associations International Journal of Obesity. 32: 740-748. PMID 18180784 DOI: 10.1038/Sj.Ijo.0803782  0.351
2007 Sinha MK, Songer T, Xiao Q, Sloan JH, Wang J, Ji S, Alborn WE, Davis RA, Swarbrick MM, Stanhope KL, Wolfe BM, Havel PJ, Schraw T, Konrad RJ, Scherer PE, et al. Analytical validation and biological evaluation of a high molecular-weight adiponectin ELISA. Clinical Chemistry. 53: 2144-51. PMID 17951289 DOI: 10.1373/Clinchem.2007.090670  0.325
2007 Kim JY, van de Wall E, Laplante M, Azzara A, Trujillo ME, Hofmann SM, Schraw T, Durand JL, Li H, Li G, Jelicks LA, Mehler MF, Hui DY, Deshaies Y, Shulman GI, ... ... Scherer PE, et al. Obesity-associated improvements in metabolic profile through expansion of adipose tissue. The Journal of Clinical Investigation. 117: 2621-37. PMID 17717599 DOI: 10.1172/Jci31021  0.739
2007 Kaplan RC, Ho GY, Xue X, Rajpathak S, Cushman M, Rohan TE, Strickler HD, Scherer PE, Anastos K. Within-individual stability of obesity-related biomarkers among women. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 16: 1291-3. PMID 17548700 DOI: 10.1158/1055-9965.Epi-06-1089  0.309
2007 Muse ED, Lam TK, Scherer PE, Rossetti L. Hypothalamic resistin induces hepatic insulin resistance. The Journal of Clinical Investigation. 117: 1670-8. PMID 17525801 DOI: 10.1172/Jci30440  0.367
2007 Basu R, Pajvani UB, Rizza RA, Scherer PE. Selective downregulation of the high molecular weight form of adiponectin in hyperinsulinemia and in type 2 diabetes: differential regulation from nondiabetic subjects. Diabetes. 56: 2174-7. PMID 17513700 DOI: 10.2337/Db07-0185  0.696
2007 Lin HV, Kim JY, Pocai A, Rossetti L, Shapiro L, Scherer PE, Accili D. Adiponectin resistance exacerbates insulin resistance in insulin receptor transgenic/knockout mice. Diabetes. 56: 1969-76. PMID 17475934 DOI: 10.2337/Db07-0127  0.68
2007 Wang ZV, Schraw TD, Kim JY, Khan T, Rajala MW, Follenzi A, Scherer PE. Secretion of the adipocyte-specific secretory protein adiponectin critically depends on thiol-mediated protein retention. Molecular and Cellular Biology. 27: 3716-31. PMID 17353260 DOI: 10.1128/Mcb.00931-06  0.799
2007 Cnop M, Vidal J, Hull RL, Utzschneider KM, Carr DB, Schraw T, Scherer PE, Boyko EJ, Fujimoto WY, Kahn SE. Progressive loss of beta-cell function leads to worsening glucose tolerance in first-degree relatives of subjects with type 2 diabetes. Diabetes Care. 30: 677-82. PMID 17327340 DOI: 10.2337/Dc06-1834  0.365
2007 Semple RK, Halberg NH, Burling K, Soos MA, Schraw T, Luan J, Cochran EK, Dunger DB, Wareham NJ, Scherer PE, Gorden P, O'Rahilly S. Paradoxical elevation of high-molecular weight adiponectin in acquired extreme insulin resistance due to insulin receptor antibodies. Diabetes. 56: 1712-7. PMID 17325257 DOI: 10.2337/Db06-1665  0.433
2007 Kim JJ, Kido Y, Scherer PE, White MF, Accili D. Analysis of compensatory beta-cell response in mice with combined mutations of Insr and Irs2. American Journal of Physiology. Endocrinology and Metabolism. 292: E1694-701. PMID 17299086 DOI: 10.1152/Ajpendo.00430.2006  0.388
2007 Fontana L, Eagon JC, Trujillo ME, Scherer PE, Klein S. Visceral fat adipokine secretion is associated with systemic inflammation in obese humans. Diabetes. 56: 1010-3. PMID 17287468 DOI: 10.2337/Db06-1656  0.36
2007 Castriota G, Thompson GM, Lin Y, Scherer PE, Moller DE, Berger JP. Peroxisome proliferator-activated receptor gamma agonists inhibit adipocyte expression of alpha1-acid glycoprotein. Cell Biology International. 31: 586-91. PMID 17240171 DOI: 10.1016/J.Cellbi.2006.11.033  0.354
2007 Li W, Tonelli J, Kishore P, Owen R, Goodman E, Scherer PE, Hawkins M. Insulin-sensitizing effects of thiazolidinediones are not linked to adiponectin receptor expression in human fat or muscle. American Journal of Physiology. Endocrinology and Metabolism. 292: E1301-7. PMID 17213476 DOI: 10.1152/Ajpendo.00312.2006  0.469
2007 Scherer PE. Adipose tissue: from lipid storage compartment to endocrine organ. Diabetes. 55: 1537-45. PMID 16731815 DOI: 10.2337/Db06-0263  0.43
2006 Ahima RS, Qi Y, Singhal NS, Jackson MB, Scherer PE. Brain adipocytokine action and metabolic regulation. Diabetes. 55: S145-54. PMID 17130638 DOI: 10.2337/Db06-S018  0.47
2006 Desruisseaux MS, Trujillo ME, Tanowitz HB, Scherer PE. Adipocyte, adipose tissue, and infectious disease. Infection and Immunity. 75: 1066-78. PMID 17118983 DOI: 10.1128/Iai.01455-06  0.446
2006 Qi Y, Nie Z, Lee YS, Singhal NS, Scherer PE, Lazar MA, Ahima RS. Loss of resistin improves glucose homeostasis in leptin deficiency. Diabetes. 55: 3083-90. PMID 17065346 DOI: 10.2337/Db05-0615  0.489
2006 Trujillo ME, Scherer PE. Adipose tissue-derived factors: impact on health and disease. Endocrine Reviews. 27: 762-78. PMID 17056740 DOI: 10.1210/Er.2006-0033  0.435
2006 Kettaneh A, Heude B, Oppert JM, Scherer P, Meyre D, Borys JM, Ducimetiere P, Charles MA. Serum adiponectin is related to plasma high-density lipoprotein cholesterol but not to plasma insulin-concentration in healthy children: the FLVS II study Metabolism: Clinical and Experimental. 55: 1171-1176. PMID 16919535 DOI: 10.1016/J.Metabol.2006.04.015  0.384
2006 Corvera S, Burkart A, Kim JY, Christianson J, Wang Z, Scherer PE. Keystone meeting summary: 'Adipogenesis, obesity, and inflammation' and 'Diabetes mellitus and the control of cellular energy metabolism, ' January 21-26, 2006, Vancouver, Canada. Genes & Development. 20: 2193-201. PMID 16912272 DOI: 10.1101/Gad.1447506  0.639
2006 Yang TT, Suk HY, Yang X, Olabisi O, Yu RY, Durand J, Jelicks LA, Kim JY, Scherer PE, Wang Y, Feng Y, Rossetti L, Graef IA, Crabtree GR, Chow CW. Role of transcription factor NFAT in glucose and insulin homeostasis. Molecular and Cellular Biology. 26: 7372-87. PMID 16908540 DOI: 10.1128/Mcb.00580-06  0.715
2006 Lara-Lemus R, Liu M, Turner MD, Scherer P, Stenbeck G, Iyengar P, Arvan P. Lumenal protein sorting to the constitutive secretory pathway of a regulated secretory cell. Journal of Cell Science. 119: 1833-42. PMID 16608874 DOI: 10.1242/Jcs.02905  0.571
2006 Kim CH, Pennisi P, Zhao H, Yakar S, Kaufman JB, Iganaki K, Shiloach J, Scherer PE, Quon MJ, LeRoith D. MKR mice are resistant to the metabolic actions of both insulin and adiponectin: discordance between insulin resistance and adiponectin responsiveness. American Journal of Physiology. Endocrinology and Metabolism. 291: E298-305. PMID 16507604 DOI: 10.1152/Ajpendo.00319.2005  0.456
2006 Bouatia-Naji N, Meyre D, Lobbens S, Séron K, Fumeron F, Balkau B, Heude B, Jouret B, Scherer PE, Dina C, Weill J, Froguel P. ACDC/adiponectin polymorphisms are associated with severe childhood and adult obesity. Diabetes. 55: 545-50. PMID 16443793 DOI: 10.2337/Diabetes.55.02.06.Db05-0971  0.323
2006 Xie L, Boyle D, Sanford D, Scherer PE, Pessin JE, Mora S. Intracellular trafficking and secretion of adiponectin is dependent on GGA-coated vesicles. The Journal of Biological Chemistry. 281: 7253-9. PMID 16407204 DOI: 10.1074/Jbc.M511313200  0.387
2006 Nawrocki AR, Rajala MW, Tomas E, Pajvani UB, Saha AK, Trumbauer ME, Pang Z, Chen AS, Ruderman NB, Chen H, Rossetti L, Scherer PE. Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists. The Journal of Biological Chemistry. 281: 2654-60. PMID 16326714 DOI: 10.1074/Jbc.M505311200  0.835
2006 Hertzel AV, Smith LA, Berg AH, Cline GW, Shulman GI, Scherer PE, Bernlohr DA. Lipid metabolism and adipokine levels in fatty acid-binding protein null and transgenic mice. American Journal of Physiology. Endocrinology and Metabolism. 290: E814-23. PMID 16303844 DOI: 10.1152/Ajpendo.00465.2005  0.69
2006 Lee D, Koppaka S, Kishore P, Li W, Tonelli J, Scherer PE, Goodman E, Hawkins M. 79 ADIPOSE TISSUE MACROPHAGES EXPRESS HIGH LEVELS OF PLASMINOGEN ACTIVATOR INHIBITOR 1 IN HUMANS AND ARE HIGHLY RESPONSIVE TO INCREASED FREE FATTY ACIDS. Journal of Investigative Medicine. 54: S387.1-S387. DOI: 10.2310/6650.2005.X0015.157  0.412
2006 Kishore P, Li W, Tonelli J, Zhang K, Scherer PE, Hawkins M. 42 ADIPONECTIN RECEPTORS ARE NOT MODULATED BY SHORT-TERM THIAZOLIDINEDIONE THERAPY. Journal of Investigative Medicine. 54: S380.3-S380. DOI: 10.2310/6650.2005.X0015.120  0.447
2006 Civitarese A, Nawrocki A, Ukropcova B, Carling S, Hulver M, DeFronzo R, Mandarino L, Scherer P, Smith S, Ravussin E. NIA0002 Novel role for adiponectin pathway in human skeletal muscle bioenergetics Obesity Reviews. 7: 37-37. DOI: 10.1111/J.1467-7881.2006.00280_8.X  0.328
2005 Nawrocki AR, Scherer PE. Keynote review: the adipocyte as a drug discovery target. Drug Discovery Today. 10: 1219-30. PMID 16213414 DOI: 10.1016/S1359-6446(05)03569-5  0.372
2005 Watson E, Hahm S, Mizuno TM, Windsor J, Montgomery C, Scherer PE, Mobbs CV, Salton SR. VGF ablation blocks the development of hyperinsulinemia and hyperglycemia in several mouse models of obesity. Endocrinology. 146: 5151-63. PMID 16141392 DOI: 10.1210/En.2005-0588  0.494
2005 Trujillo ME, Pajvani UB, Scherer PE. Apoptosis through targeted activation of caspase 8 ("ATTAC-mice"): novel mouse models of inducible and reversible tissue ablation. Cell Cycle (Georgetown, Tex.). 4: 1141-5. PMID 16096375 DOI: 10.4161/Cc.4.9.2030  0.719
2005 Halperin F, Beckman JA, Patti ME, Trujillo ME, Garvin M, Creager MA, Scherer PE, Goldfine AB. The role of total and high-molecular-weight complex of adiponectin in vascular function in offspring whose parents both had type 2 diabetes Diabetologia. 48: 2147-2154. PMID 16091909 DOI: 10.1007/S00125-005-1901-5  0.328
2005 Jürgens H, Haass W, Castañeda TR, Schürmann A, Koebnick C, Dombrowski F, Otto B, Nawrocki AR, Scherer PE, Spranger J, Ristow M, Joost HG, Havel PJ, Tschöp MH. Consuming fructose-sweetened beverages increases body adiposity in mice. Obesity Research. 13: 1146-56. PMID 16076983 DOI: 10.1038/Oby.2005.136  0.348
2005 Graveleau C, Zaha VG, Mohajer A, Banerjee RR, Dudley-Rucker N, Steppan CM, Rajala MW, Scherer PE, Ahima RS, Lazar MA, Abel ED. Mouse and human resistins impair glucose transport in primary mouse cardiomyocytes, and oligomerization is required for this biological action. The Journal of Biological Chemistry. 280: 31679-85. PMID 15983036 DOI: 10.1074/Jbc.M504008200  0.731
2005 Pajvani UB, Trujillo ME, Combs TP, Iyengar P, Jelicks L, Roth KA, Kitsis RN, Scherer PE. Fat apoptosis through targeted activation of caspase 8: a new mouse model of inducible and reversible lipoatrophy. Nature Medicine. 11: 797-803. PMID 15965483 DOI: 10.1038/Nm1262  0.788
2005 Fisher FM, Trujillo ME, Hanif W, Barnett AH, McTernan PG, Scherer PE, Kumar S. Serum high molecular weight complex of adiponectin correlates better with glucose tolerance than total serum adiponectin in Indo-Asian males. Diabetologia. 48: 1084-7. PMID 15902402 DOI: 10.1007/S00125-005-1758-7  0.343
2005 Berg AH, Scherer PE. Adipose tissue, inflammation, and cardiovascular disease. Circulation Research. 96: 939-49. PMID 15890981 DOI: 10.1161/01.Res.0000163635.62927.34  0.683
2005 Satoh H, Nguyen MT, Trujillo M, Imamura T, Usui I, Scherer PE, Olefsky JM. Adenovirus-mediated adiponectin expression augments skeletal muscle insulin sensitivity in male Wistar rats. Diabetes. 54: 1304-13. PMID 15855314 DOI: 10.2337/Diabetes.54.5.1304  0.454
2005 Combs TP, Nagajyothi, Mukherjee S, de Almeida CJ, Jelicks LA, Schubert W, Lin Y, Jayabalan DS, Zhao D, Braunstein VL, Landskroner-Eiger S, Cordero A, Factor SM, Weiss LM, Lisanti MP, ... ... Scherer PE, et al. The adipocyte as an important target cell for Trypanosoma cruzi infection. The Journal of Biological Chemistry. 280: 24085-94. PMID 15843370 DOI: 10.1074/Jbc.M412802200  0.804
2005 Iyengar P, Espina V, Williams TW, Lin Y, Berry D, Jelicks LA, Lee H, Temple K, Graves R, Pollard J, Chopra N, Russell RG, Sasisekharan R, Trock BJ, Lippman M, ... ... Scherer PE, et al. Adipocyte-derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment. The Journal of Clinical Investigation. 115: 1163-76. PMID 15841211 DOI: 10.1172/Jci23424  0.581
2005 Vasseur F, Helbecque N, Lobbens S, Vasseur-Delannoy V, Dina C, Clément K, Boutin P, Kadowaki T, Scherer PE, Froguel P. Hypoadiponectinaemia and high risk of type 2 diabetes are associated with adiponectin-encoding (ACDC) gene promoter variants in morbid obesity: evidence for a role of ACDC in diabesity. Diabetologia. 48: 892-9. PMID 15830179 DOI: 10.1007/S00125-005-1729-Z  0.316
2005 Cohen AW, Schubert W, Brasaemle DL, Scherer PE, Lisanti MP. Caveolin-1 expression is essential for proper nonshivering thermogenesis in brown adipose tissue. Diabetes. 54: 679-86. PMID 15734843 DOI: 10.2337/Diabetes.54.3.679  0.436
2005 Bouskila M, Pajvani UB, Scherer PE. Adiponectin: a relevant player in PPARgamma-agonist-mediated improvements in hepatic insulin sensitivity? International Journal of Obesity (2005). 29: S17-23. PMID 15711577 DOI: 10.1038/Sj.Ijo.0802908  0.723
2005 Capozza F, Combs TP, Cohen AW, Cho YR, Park SY, Schubert W, Williams TM, Brasaemle DL, Jelicks LA, Scherer PE, Kim JK, Lisanti MP. Caveolin-3 knockout mice show increased adiposity and whole body insulin resistance, with ligand-induced insulin receptor instability in skeletal muscle. American Journal of Physiology. Cell Physiology. 288: C1317-31. PMID 15689413 DOI: 10.1152/Ajpcell.00489.2004  0.485
2005 Bonuccelli G, Sotgia F, Frank PG, Williams TM, de Almeida CJ, Tanowitz HB, Scherer PE, Hotchkiss KA, Terman BI, Rollman B, Alileche A, Brojatsch J, Lisanti MP. ATR/TEM8 is highly expressed in epithelial cells lining Bacillus anthracis' three sites of entry: implications for the pathogenesis of anthrax infection. American Journal of Physiology. Cell Physiology. 288: C1402-10. PMID 15689409 DOI: 10.1152/Ajpcell.00582.2004  0.314
2005 Trujillo ME, Scherer PE. Adiponectin--journey from an adipocyte secretory protein to biomarker of the metabolic syndrome. Journal of Internal Medicine. 257: 167-75. PMID 15656875 DOI: 10.1111/J.1365-2796.2004.01426.X  0.407
2005 Lin Y, Berg AH, Iyengar P, Lam TK, Giacca A, Combs TP, Rajala MW, Du X, Rollman B, Li W, Hawkins M, Barzilai N, Rhodes CJ, Fantus IG, Brownlee M, ... Scherer PE, et al. The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species. The Journal of Biological Chemistry. 280: 4617-26. PMID 15536073 DOI: 10.1074/Jbc.M411863200  0.82
2004 Kim JY, Scherer PE. Adiponectin, an adipocyte-derived hepatic insulin sensitizer regulation during development. Pediatric Endocrinology Reviews : Per. 1: 428-31. PMID 16444169  0.651
2004 Leprêtre F, Linton KJ, Lacquemant C, Vatin V, Samson C, Dina C, Chikri M, Ali S, Scherer P, Séron K, Vasseur F, Aitman T, Froguel P. Genetic study of the CD36 gene in a French diabetic population. Diabetes & Metabolism. 30: 459-63. PMID 15671915 DOI: 10.1016/S1262-3636(07)70143-X  0.307
2004 Kim H, Haluzik M, Gavrilova O, Yakar S, Portas J, Sun H, Pajvani UB, Scherer PE, LeRoith D. Thiazolidinediones improve insulin sensitivity in adipose tissue and reduce the hyperlipidaemia without affecting the hyperglycaemia in a transgenic model of type 2 diabetes. Diabetologia. 47: 2215-25. PMID 15662559 DOI: 10.1007/S00125-004-1581-6  0.683
2004 Florant GL, Porst H, Peiffer A, Hudachek SF, Pittman C, Summers SA, Rajala MW, Scherer PE. Fat-cell mass, serum leptin and adiponectin changes during weight gain and loss in yellow-bellied marmots (Marmota flaviventris). Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology. 174: 633-9. PMID 15517283 DOI: 10.1007/S00360-004-0454-0  0.742
2004 Williams TM, Medina F, Badano I, Hazan RB, Hutchinson J, Muller WJ, Chopra NG, Scherer PE, Pestell RG, Lisanti MP. Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo. Role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion. The Journal of Biological Chemistry. 279: 51630-46. PMID 15355971 DOI: 10.1074/Jbc.M409214200  0.322
2004 Mancia F, Patel SD, Rajala MW, Scherer PE, Nemes A, Schieren I, Hendrickson WA, Shapiro L. Optimization of protein production in mammalian cells with a coexpressed fluorescent marker Structure. 12: 1355-1360. PMID 15296729 DOI: 10.1016/J.Str.2004.06.012  0.673
2004 Muse ED, Obici S, Bhanot S, Monia BP, McKay RA, Rajala MW, Scherer PE, Rossetti L. Role of resistin in diet-induced hepatic insulin resistance. The Journal of Clinical Investigation. 114: 232-9. PMID 15254590 DOI: 10.1172/Jci21270  0.753
2004 Berg AH, Lin Y, Lisanti MP, Scherer PE. Adipocyte differentiation induces dynamic changes in NF-kappaB expression and activity. American Journal of Physiology. Endocrinology and Metabolism. 287: E1178-88. PMID 15251865 DOI: 10.1152/Ajpendo.00002.2004  0.665
2004 Leprêtre F, Vasseur F, Vaxillaire M, Scherer PE, Ali S, Linton K, Aitman T, Froguel P. A CD36 nonsense mutation associated with insulin resistance and familial type 2 diabetes. Human Mutation. 24: 104. PMID 15221799 DOI: 10.1002/Humu.9256  0.367
2004 Rajala MW, Qi Y, Patel HR, Takahashi N, Banerjee R, Pajvani UB, Sinha MK, Gingerich RL, Scherer PE, Ahima RS. Regulation of resistin expression and circulating levels in obesity, diabetes, and fasting. Diabetes. 53: 1671-9. PMID 15220189 DOI: 10.2337/Diabetes.53.7.1671  0.835
2004 Tonelli J, Li W, Kishore P, Pajvani UB, Kwon E, Weaver C, Scherer PE, Hawkins M. Mechanisms of early insulin-sensitizing effects of thiazolidinediones in type 2 diabetes. Diabetes. 53: 1621-9. PMID 15161771 DOI: 10.2337/Diabetes.53.6.1621  0.713
2004 Patel SD, Rajala MW, Rossetti L, Scherer PE, Shapiro L. Disulfide-dependent multimeric assembly of resistin family hormones. Science (New York, N.Y.). 304: 1154-8. PMID 15155948 DOI: 10.1126/Science.1093466  0.728
2004 Nawrocki AR, Scherer PE. The delicate balance between fat and muscle: adipokines in metabolic disease and musculoskeletal inflammation. Current Opinion in Pharmacology. 4: 281-9. PMID 15140421 DOI: 10.1016/J.Coph.2004.03.003  0.458
2004 Cohen AW, Razani B, Schubert W, Williams TM, Wang XB, Iyengar P, Brasaemle DL, Scherer PE, Lisanti MP. Role of caveolin-1 in the modulation of lipolysis and lipid droplet formation. Diabetes. 53: 1261-70. PMID 15111495 DOI: 10.2337/Diabetes.53.5.1261  0.614
2004 Qi Y, Takahashi N, Hileman SM, Patel HR, Berg AH, Pajvani UB, Scherer PE, Ahima RS. Adiponectin acts in the brain to decrease body weight. Nature Medicine. 10: 524-9. PMID 15077108 DOI: 10.1038/Nm1029  0.776
2004 Williams TM, Lee H, Cheung MW, Cohen AW, Razani B, Iyengar P, Scherer PE, Pestell RG, Lisanti MP. Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: role of INK4a/CAV-1 in mammary epithelial cell hyperplasia. The Journal of Biological Chemistry. 279: 24745-56. PMID 15044451 DOI: 10.1074/Jbc.M402064200  0.57
2004 Banerjee RR, Rangwala SM, Shapiro JS, Rich AS, Rhoades B, Qi Y, Wang J, Rajala MW, Pocai A, Scherer PE, Steppan CM, Ahima RS, Obici S, Rossetti L, Lazar MA. Regulation of fasted blood glucose by resistin. Science (New York, N.Y.). 303: 1195-8. PMID 14976316 DOI: 10.1126/Science.1092341  0.718
2004 Kumar S, Coenen MJ, Scherer PE, Bahn RS. Evidence for enhanced adipogenesis in the orbits of patients with Graves' ophthalmopathy. The Journal of Clinical Endocrinology and Metabolism. 89: 930-5. PMID 14764816 DOI: 10.1210/Jc.2003-031427  0.38
2004 Pajvani UB, Hawkins M, Combs TP, Rajala MW, Doebber T, Berger JP, Wagner JA, Wu M, Knopps A, Xiang AH, Utzschneider KM, Kahn SE, Olefsky JM, Buchanan TA, Scherer PE. Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity. The Journal of Biological Chemistry. 279: 12152-62. PMID 14699128 DOI: 10.1074/Jbc.M311113200  0.821
2004 Combs TP, Pajvani UB, Berg AH, Lin Y, Jelicks LA, Laplante M, Nawrocki AR, Rajala MW, Parlow AF, Cheeseboro L, Ding YY, Russell RG, Lindemann D, Hartley A, Baker GR, ... ... Scherer PE, et al. A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity. Endocrinology. 145: 367-83. PMID 14576179 DOI: 10.1210/En.2003-1068  0.84
2004 Kishore P, Li WJ, Tonelli J, Weaver C, Scherer P, Goodman E, Hawkins M. 29 PIOGLITAZONE RAPIDLY AFFECTS ADIPOSE TISSUE GENE EXPRESSION AND INSULIN ACTION IN HUMANS WITH TYPE 2 DIABETES MELLITUS (T2DM). Journal of Investigative Medicine. 52: S381.6-S382. DOI: 10.1136/Jim-52-Suppl2-103  0.411
2004 Qi Y, Takahashi N, Hileman SM, Patel HR, Berg AH, Pajvani UB, Scherer PE, Ahima RS. Erratum: Adiponectin acts in the brain to decrease body weight Nature Medicine. 10: 649-649. DOI: 10.1038/Nm0604-649A  0.718
2003 Iyengar P, Scherer PE. Adiponectin/Acrp30, an adipocyte-specific secretory factor: physiological relevance during development. Pediatric Diabetes. 4: 32-7. PMID 14655522 DOI: 10.1034/J.1399-5448.2003.00029.X  0.685
2003 Cohen AW, Combs TP, Scherer PE, Lisanti MP. Role of caveolin and caveolae in insulin signaling and diabetes. American Journal of Physiology. Endocrinology and Metabolism. 285: E1151-60. PMID 14607781 DOI: 10.1152/Ajpendo.00324.2003  0.443
2003 Iyengar P, Combs TP, Shah SJ, Gouon-Evans V, Pollard JW, Albanese C, Flanagan L, Tenniswood MP, Guha C, Lisanti MP, Pestell RG, Scherer PE. Adipocyte-secreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and proto-oncogene stabilization. Oncogene. 22: 6408-23. PMID 14508521 DOI: 10.1038/Sj.Onc.1206737  0.601
2003 Rajala MW, Scherer PE. Minireview: The adipocyte--at the crossroads of energy homeostasis, inflammation, and atherosclerosis. Endocrinology. 144: 3765-73. PMID 12933646 DOI: 10.1210/En.2003-0580  0.752
2003 Pajvani UB, Scherer PE. Adiponectin: systemic contributor to insulin sensitivity. Current Diabetes Reports. 3: 207-13. PMID 12762967 DOI: 10.1007/S11892-003-0065-2  0.749
2003 Cohen AW, Razani B, Wang XB, Combs TP, Williams TM, Scherer PE, Lisanti MP. Caveolin-1-deficient mice show insulin resistance and defective insulin receptor protein expression in adipose tissue. American Journal of Physiology. Cell Physiology. 285: C222-35. PMID 12660144 DOI: 10.1152/Ajpcell.00006.2003  0.478
2003 Koshkin V, Wang X, Scherer PE, Chan CB, Wheeler MB. Mitochondrial functional state in clonal pancreatic β-cells exposed to free fatty acids Journal of Biological Chemistry. 278: 19709-19715. PMID 12642585 DOI: 10.1074/Jbc.M209709200  0.381
2003 Combs TP, Berg AH, Rajala MW, Klebanov S, Iyengar P, Jimenez-Chillaron JC, Patti ME, Klein SL, Weinstein RS, Scherer PE. Sexual differentiation, pregnancy, calorie restriction, and aging affect the adipocyte-specific secretory protein adiponectin. Diabetes. 52: 268-76. PMID 12540596 DOI: 10.2337/Diabetes.52.2.268  0.806
2003 Rajala MW, Obici S, Scherer PE, Rossetti L. Adipose-derived resistin and gut-derived resistin-like molecule-beta selectively impair insulin action on glucose production. The Journal of Clinical Investigation. 111: 225-30. PMID 12531878 DOI: 10.1172/Jci16521  0.759
2003 Pajvani UB, Du X, Combs TP, Berg AH, Rajala MW, Schulthess T, Engel J, Brownlee M, Scherer PE. Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications fpr metabolic regulation and bioactivity. The Journal of Biological Chemistry. 278: 9073-85. PMID 12496257 DOI: 10.1074/Jbc.M207198200  0.807
2003 Mynarcik DC, Combs T, McNurlan MA, Scherer PE, Komaroff E, Gelato MC. Adiponectin and leptin levels in HIV-infected subjects with insulin resistance and body fat redistribution. Journal of Acquired Immune Deficiency Syndromes (1999). 31: 514-20. PMID 12473840 DOI: 10.1097/00126334-200212150-00009  0.318
2002 Combs TP, Wagner JA, Berger J, Doebber T, Wang WJ, Zhang BB, Tanen M, Berg AH, O'Rahilly S, Savage DB, Chatterjee K, Weiss S, Larson PJ, Gottesdiener KM, Gertz BJ, ... ... Scherer PE, et al. Induction of Adipocyte Complement-Related Protein of 30 Kilodaltons by PPARγ Agonists: A Potential Mechanism of Insulin Sensitization. Endocrinology. 143: 998-1007. PMID 28201619 DOI: 10.1210/endo.143.3.8662  0.657
2002 Somwar R, Koterski S, Sweeney G, Sciotti R, Djuric S, Berg C, Trevillyan J, Scherer PE, Rondinone CM, Klip A. A dominant-negative p38 MAPK mutant and novel selective inhibitors of p38 MAPK reduce insulin-stimulated glucose uptake in 3T3-L1 adipocytes without affecting GLUT4 translocation. The Journal of Biological Chemistry. 277: 50386-95. PMID 12393894 DOI: 10.1074/Jbc.M205277200  0.353
2002 Gabriely I, Ma XH, Yang XM, Atzmon G, Rajala MW, Berg AH, Scherer P, Rossetti L, Barzilai N. Removal of visceral fat prevents insulin resistance and glucose intolerance of aging: an adipokine-mediated process? Diabetes. 51: 2951-8. PMID 12351432 DOI: 10.2337/Diabetes.51.10.2951  0.813
2002 Rajala MW, Lin Y, Ranalletta M, Yang XM, Qian H, Gingerich R, Barzilai N, Scherer PE. Cell type-specific expression and coregulation of murine resistin and resistin-like molecule-alpha in adipose tissue. Molecular Endocrinology (Baltimore, Md.). 16: 1920-30. PMID 12145345 DOI: 10.1210/Me.2002-0048  0.76
2002 Kratchmarova I, Kalume DE, Blagoev B, Scherer PE, Podtelejnikov AV, Molina H, Bickel PE, Andersen JS, Fernandez MM, Bunkenborg J, Roepstorff P, Kristiansen K, Lodish HF, Mann M, Pandey A. A proteomic approach for identification of secreted proteins during the differentiation of 3T3-L1 preadipocytes to adipocytes. Molecular & Cellular Proteomics : McP. 1: 213-22. PMID 12096121 DOI: 10.1074/Mcp.M200006-Mcp200  0.35
2002 Lee H, Park DS, Wang XB, Scherer PE, Schwartz PE, Lisanti MP. Src-induced phosphorylation of caveolin-2 on tyrosine 19. Phospho-caveolin-2 (Tyr(P)19) is localized near focal adhesions, remains associated with lipid rafts/caveolae, but no longer forms a high molecular mass hetero-oligomer with caveolin-1. The Journal of Biological Chemistry. 277: 34556-67. PMID 12091389 DOI: 10.1074/Jbc.M204367200  0.323
2002 Menzaghi C, Ercolino T, Di Paola R, Berg AH, Warram JH, Scherer PE, Trischitta V, Doria A. A haplotype at the adiponectin locus is associated with obesity and other features of the insulin resistance syndrome. Diabetes. 51: 2306-12. PMID 12086965 DOI: 10.2337/Diabetes.51.7.2306  0.684
2002 Razani B, Park DS, Miyanaga Y, Ghatpande A, Cohen J, Wang XB, Scherer PE, Evans T, Lisanti MP. Molecular cloning and developmental expression of the caveolin gene family in the amphibian Xenopus laevis. Biochemistry. 41: 7914-24. PMID 12069580 DOI: 10.1021/Bi020043N  0.307
2002 Combs TP, Wagner JA, Berger J, Doebber T, Wang WJ, Zhang BB, Tanen M, Berg AH, O'Rahilly S, Savage DB, Chatterjee K, Weiss S, Larson PJ, Gottesdiener KM, Gertz BJ, ... ... Scherer PE, et al. Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: a potential mechanism of insulin sensitization. Endocrinology. 143: 998-1007. PMID 11861525 DOI: 10.1210/Endo.143.3.8662  0.735
2002 Berg AH, Combs TP, Scherer PE. ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism. Trends in Endocrinology and Metabolism: Tem. 13: 84-9. PMID 11854024 DOI: 10.1016/S1043-2760(01)00524-0  0.723
2002 Razani B, Combs TP, Wang XB, Frank PG, Park DS, Russell RG, Li M, Tang B, Jelicks LA, Scherer PE, Lisanti MP. Caveolin-1-deficient mice are lean, resistant to diet-induced obesity, and show hypertriglyceridemia with adipocyte abnormalities. The Journal of Biological Chemistry. 277: 8635-47. PMID 11739396 DOI: 10.1074/Jbc.M110970200  0.463
2001 Combs TP, Berg AH, Obici S, Scherer PE, Rossetti L. Endogenous glucose production is inhibited by the adipose-derived protein Acrp30. The Journal of Clinical Investigation. 108: 1875-81. PMID 11748271 DOI: 10.1172/Jci14120  0.668
2001 Park DS, Lee H, Riedel C, Hulit J, Scherer PE, Pestell RG, Lisanti MP. Prolactin negatively regulates caveolin-1 gene expression in the mammary gland during lactation, via a Ras-dependent mechanism. The Journal of Biological Chemistry. 276: 48389-97. PMID 11602600 DOI: 10.1074/Jbc.M108210200  0.356
2001 Lin Y, Rajala MW, Berger JP, Moller DE, Barzilai N, Scherer PE. Hyperglycemia-induced production of acute phase reactants in adipose tissue. The Journal of Biological Chemistry. 276: 42077-83. PMID 11546817 DOI: 10.1074/Jbc.M107101200  0.738
2001 Berg AH, Combs TP, Du X, Brownlee M, Scherer PE. The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nature Medicine. 7: 947-53. PMID 11479628 DOI: 10.1038/90992  0.732
2001 Das K, Lin Y, Widen E, Zhang Y, Scherer PE. Chromosomal localization, expression pattern, and promoter analysis of the mouse gene encoding adipocyte-specific secretory protein Acrp30. Biochemical and Biophysical Research Communications. 280: 1120-9. PMID 11162643 DOI: 10.1006/Bbrc.2001.4217  0.358
2000 Lee H, Volonte D, Galbiati F, Iyengar P, Lublin DM, Bregman DB, Wilson MT, Campos-Gonzalez R, Bouzahzah B, Pestell RG, Scherer PE, Lisanti MP. Constitutive and growth factor-regulated phosphorylation of caveolin-1 occurs at the same site (Tyr-14) in vivo: identification of a c-Src/Cav-1/Grb7 signaling cassette. Molecular Endocrinology (Baltimore, Md.). 14: 1750-75. PMID 11075810 DOI: 10.1210/Mend.14.11.0553  0.543
2000 Engelman JA, Berg AH, Lewis RY, Lisanti MP, Scherer PE. Tumor necrosis factor alpha-mediated insulin resistance, but not dedifferentiation, is abrogated by MEK1/2 inhibitors in 3T3-L1 adipocytes. Molecular Endocrinology (Baltimore, Md.). 14: 1557-69. PMID 11043572 DOI: 10.1210/Mend.14.10.0542  0.68
2000 Lin Y, Lee H, Berg AH, Lisanti MP, Shapiro L, Scherer PE. The lipopolysaccharide-activated toll-like receptor (TLR)-4 induces synthesis of the closely related receptor TLR-2 in adipocytes. The Journal of Biological Chemistry. 275: 24255-63. PMID 10823826 DOI: 10.1074/Jbc.M002137200  0.631
1999 Engelman JA, Berg AH, Lewis RY, Lin A, Lisanti MP, Scherer PE. Constitutively active mitogen-activated protein kinase kinase 6 (MKK6) or salicylate induces spontaneous 3T3-L1 adipogenesis. The Journal of Biological Chemistry. 274: 35630-8. PMID 10585441 DOI: 10.1074/Jbc.274.50.35630  0.63
1999 Das K, Lewis RY, Combatsiaris TP, Lin Y, Shapiro L, Charron MJ, Scherer PE. Predominant expression of the mitochondrial dicarboxylate carrier in white adipose tissue Biochemical Journal. 344: 313-320. PMID 10567211 DOI: 10.1042/0264-6021:3440313  0.339
1999 Galbiati F, Volonte D, Engelman JA, Scherer PE, Lisanti MP. Targeted down-regulation of caveolin-3 is sufficient to inhibit myotube formation in differentiating C2C12 myoblasts. Transient activation of p38 mitogen-activated protein kinase is required for induction of caveolin-3 expression and subsequent myotube formation. The Journal of Biological Chemistry. 274: 30315-21. PMID 10514527 DOI: 10.1074/Jbc.274.42.30315  0.308
1999 Das K, Lewis RY, Scherer PE, Lisanti MP. The membrane-spanning domains of caveolins-1 and -2 mediate the formation of caveolin hetero-oligomers. Implications for tile assembly of caveolae membranes in vivo Journal of Biological Chemistry. 274: 18721-18728. PMID 10373486 DOI: 10.1074/Jbc.274.26.18721  0.301
1998 Shapiro L, Scherer PE. The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor. Current Biology : Cb. 8: 335-8. PMID 9512423 DOI: 10.1016/S0960-9822(98)70133-2  0.32
1997 Scherer PE, Lewis RY, Volonte D, Engelman JA, Galbiati F, Couet J, Kohtz DS, van Donselaar E, Peters P, Lisanti MP. Cell-type and tissue-specific expression of caveolin-2. Caveolins 1 and 2 co-localize and form a stable hetero-oligomeric complex in vivo. The Journal of Biological Chemistry. 272: 29337-46. PMID 9361015 DOI: 10.1074/Jbc.272.46.29337  0.348
1997 Scherer PE, Lisanti MP. Association of phosphofructokinase-M with caveolin-3 in differentiated skeletal myotubes: Dynamic regulation by extracellular glucose and intracellular metabolites Journal of Biological Chemistry. 272: 20698-20705. PMID 9252390 DOI: 10.1074/Jbc.272.33.20698  0.325
1996 Scherer PE, Okamoto T, Chun M, Nishimoto I, Lodish HF, Lisanti MP. Identification, sequence, and expression of caveolin-2 defines a caveolin gene family Proceedings of the National Academy of Sciences of the United States of America. 93: 131-135. PMID 8552590 DOI: 10.1073/Pnas.93.1.131  0.32
1995 Baldini G, Scherer PE, Lodish HF. Nonneuronal expression of Rab3A: induction during adipogenesis and association with different intracellular membranes than Rab3D. Proceedings of the National Academy of Sciences of the United States of America. 92: 4284-8. PMID 7753798 DOI: 10.1073/Pnas.92.10.4284  0.334
1995 Scherer PE, Williams S, Fogliano M, Baldini G, Lodish HF. A novel serum protein similar to C1q, produced exclusively in adipocytes. The Journal of Biological Chemistry. 270: 26746-9. PMID 7592907 DOI: 10.1074/Jbc.270.45.26746  0.43
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