Rajesh Ambasudhan - Publications

Affiliations: 
Scripps Research Institute, La Jolla, La Jolla, CA, United States 

17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Lee M, Kim J, Ambasudhan R. Direct Reprogramming of Human Fibroblasts into Induced Neural Progenitor Cells Using Suicide Gene Embodied Episomal Vectors for Rapid Selection of Exogenous DNA-Free Cells. Methods in Molecular Biology (Clifton, N.J.). 2239: 61-75. PMID 33226613 DOI: 10.1007/978-1-0716-1084-8_5  0.794
2020 Ghatak S, Dolatabadi N, Gao R, Wu Y, Scott H, Trudler D, Sultan A, Ambasudhan R, Nakamura T, Masliah E, Talantova M, Voytek B, Lipton SA. NitroSynapsin ameliorates hypersynchronous neural network activity in Alzheimer hiPSC models. Molecular Psychiatry. PMID 32467645 DOI: 10.1038/S41380-020-0776-7  0.34
2018 Ryan T, Bamm VV, Stykel MG, Coackley CL, Humphries KM, Jamieson-Williams R, Ambasudhan R, Mosser DD, Lipton SA, Harauz G, Ryan SD. Cardiolipin exposure on the outer mitochondrial membrane modulates α-synuclein. Nature Communications. 9: 817. PMID 29483518 DOI: 10.1038/S41467-018-03241-9  0.31
2017 Oh CK, Sultan A, Platzer J, Dolatabadi N, Soldner F, McClatchy DB, Diedrich JK, Yates JR, Ambasudhan R, Nakamura T, Jaenisch R, Lipton SA. S-Nitrosylation of PINK1 Attenuates PINK1/Parkin-Dependent Mitophagy in hiPSC-Based Parkinson's Disease Models. Cell Reports. 21: 2171-2182. PMID 29166608 DOI: 10.1016/J.Celrep.2017.10.068  0.314
2016 Sunico CR, Sultan A, Nakamura T, Dolatabadi N, Parker J, Shan B, Han X, Yates JR, Masliah E, Ambasudhan R, Nakanishi N, Lipton SA. Role of sulfiredoxin as a peroxiredoxin-2 denitrosylase in human iPSC-derived dopaminergic neurons. Proceedings of the National Academy of Sciences of the United States of America. PMID 27821734 DOI: 10.1073/Pnas.1608784113  0.412
2016 Jiang J, Chan A, Ali S, Saha A, Haushalter KJ, Lam WM, Glasheen M, Parker J, Brenner M, Mahon SB, Patel HH, Ambasudhan R, Lipton SA, Pilz RB, Boss GR. Hydrogen Sulfide-Mechanisms of Toxicity and Development of an Antidote. Scientific Reports. 6: 20831. PMID 26877209 DOI: 10.1038/Srep20831  0.381
2014 Ambasudhan R, Dolatabadi N, Nutter A, Masliah E, Mckercher SR, Lipton SA. Potential for cell therapy in Parkinson's disease using genetically programmed human embryonic stem cell-derived neural progenitor cells. The Journal of Comparative Neurology. 522: 2845-56. PMID 24756727 DOI: 10.1002/Cne.23617  0.519
2014 Zhu S, Ambasudhan R, Sun W, Kim HJ, Talantova M, Wang X, Zhang M, Zhang Y, Laurent T, Parker J, Kim HS, Zaremba JD, Saleem S, Sanz-Blasco S, Masliah E, et al. Small molecules enable OCT4-mediated direct reprogramming into expandable human neural stem cells. Cell Research. 24: 126-9. PMID 24296783 DOI: 10.1038/Cr.2013.156  0.767
2013 Ryan SD, Dolatabadi N, Chan SF, Zhang X, Akhtar MW, Parker J, Soldner F, Sunico CR, Nagar S, Talantova M, Lee B, Lopez K, Nutter A, Shan B, Molokanova E, ... ... Ambasudhan R, et al. Isogenic human iPSC Parkinson's model shows nitrosative stress-induced dysfunction in MEF2-PGC1α transcription. Cell. 155: 1351-64. PMID 24290359 DOI: 10.1016/J.Cell.2013.11.009  0.328
2013 Ambasudhan R, Parker J, Ainza C, Dolatabadi N, Ryan S, Le T, Lipton SA, Haas RH. A human reprogrammed-cell model of MELAS Mitochondrion. 13: 943-944. DOI: 10.1016/j.mito.2013.07.112  0.405
2012 Piña-Crespo JC, Talantova M, Cho EG, Soussou W, Dolatabadi N, Ryan SD, Ambasudhan R, McKercher S, Deisseroth K, Lipton SA. High-frequency hippocampal oscillations activated by optogenetic stimulation of transplanted human ESC-derived neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 15837-42. PMID 23136422 DOI: 10.1523/Jneurosci.3735-12.2012  0.303
2012 Kim J, Ambasudhan R, Ding S. Direct lineage reprogramming to neural cells. Current Opinion in Neurobiology. 22: 778-84. PMID 22652035 DOI: 10.1016/J.Conb.2012.05.001  0.79
2011 Ambasudhan R, Talantova M, Coleman R, Yuan X, Zhu S, Lipton SA, Ding S. Direct reprogramming of adult human fibroblasts to functional neurons under defined conditions. Cell Stem Cell. 9: 113-8. PMID 21802386 DOI: 10.1016/j.stem.2011.07.002  0.795
2011 Li W, Sun W, Zhang Y, Wei W, Ambasudhan R, Xia P, Talantova M, Lin T, Kim J, Wang X, Kim WR, Lipton SA, Zhang K, Ding S. Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 108: 8299-304. PMID 21525408 DOI: 10.1073/Pnas.1014041108  0.714
2010 Zhu S, Li W, Zhou H, Wei W, Ambasudhan R, Lin T, Kim J, Zhang K, Ding S. Reprogramming of human primary somatic cells by OCT4 and chemical compounds. Cell Stem Cell. 7: 651-5. PMID 21112560 DOI: 10.1016/J.Stem.2010.11.015  0.649
2009 Lin T, Ambasudhan R, Yuan X, Li W, Hilcove S, Abujarour R, Lin X, Hahm HS, Hao E, Hayek A, Ding S. A chemical platform for improved induction of human iPSCs. Nature Methods. 6: 805-8. PMID 19838168 DOI: 10.1038/Nmeth.1393  0.666
2007 Ambasudhan R, Ding S. An "Orphan" Finds a Home in NSC Regulation Chemistry and Biology. 14: 974-975. PMID 17884628 DOI: 10.1016/J.Chembiol.2007.09.001  0.673
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