| Year |
Citation |
Score |
| 2024 |
Accili D, Talchai SC, Bouchi R, Lee AY, Du W, Kitamoto T, McKimpson WM, Belvedere S, Lin HV. Diabetes treatment by conversion of gut epithelial cells to insulin-producing cells. Journal of Diabetes Investigation. PMID 38426644 DOI: 10.1111/jdi.14175 |
0.5 |
|
| 2024 |
Watanabe H, Asahara SI, Son J, McKimpson WM, de Cabo R, Accili D. Cyb5r3 activation rescues secondary failure to sulfonylurea but not β-cell dedifferentiation. Plos One. 19: e0297555. PMID 38335173 DOI: 10.1371/journal.pone.0297555 |
0.388 |
|
| 2024 |
Suda N, Bartolomé A, Liang J, Son J, Yagishita Y, Siebel C, Accili D, Ding H, Pajvani UB. β-cell Jagged1 is sufficient but not necessary for islet Notch activity and insulin secretory defects in obese mice. Molecular Metabolism. 81: 101894. PMID 38311286 DOI: 10.1016/j.molmet.2024.101894 |
0.352 |
|
| 2023 |
Pajvani UB, Shawber CJ, Samuel VT, Birkenfeld AL, Shulman GI, Kitajewski J, Accili D. Author Correction: Inhibition of Notch signaling ameliorates insulin resistance in a FoxO1-dependent manner. Nature Medicine. PMID 38041001 DOI: 10.1038/s41591-023-02695-9 |
0.359 |
|
| 2023 |
Park J, Hall C, Hubbard B, LaMoia T, Gaspar R, Nasiri A, Li F, Zhang H, Kim J, Haeusler RA, Accili D, Shulman GI, Yu H, Choi E. MAD2-dependent insulin receptor endocytosis regulates metabolic homeostasis. Diabetes. PMID 37725942 DOI: 10.2337/db23-0314 |
0.486 |
|
| 2023 |
Son J, Accili D. Reversing pancreatic β-cell dedifferentiation in the treatment of type 2 diabetes. Experimental & Molecular Medicine. 55: 1652-1658. PMID 37524865 DOI: 10.1038/s12276-023-01043-8 |
0.402 |
|
| 2023 |
Kitamoto T, Accili D. Unraveling the mysteries of hepatic insulin signaling: deconvoluting the nuclear targets of insulin. Endocrine Journal. PMID 37245960 DOI: 10.1507/endocrj.EJ23-0150 |
0.491 |
|
| 2023 |
Son J, Du W, Esposito M, Shariati K, Ding H, Kang Y, Accili D. Genetic and pharmacologic inhibition of ALDH1A3 as a treatment of β-cell failure. Nature Communications. 14: 558. PMID 36732513 DOI: 10.1038/s41467-023-36315-4 |
0.312 |
|
| 2023 |
Watanabe H, Du W, Son J, Sui L, Asahara SI, Kurland IJ, Kuo T, Kitamoto T, Miyachi Y, de Cabo R, Accili D. Cyb5r3-based mechanism and reversal of secondary failure to sulfonylurea in diabetes. Science Translational Medicine. 15: eabq4126. PMID 36724243 DOI: 10.1126/scitranslmed.abq4126 |
0.367 |
|
| 2022 |
Accili D, Du W, Kitamoto T, Kuo T, McKimpson W, Miyachi Y, Mukhanova M, Son J, Wang L, Watanabe H. Reflections on the state of diabetes research and prospects for treatment. Diabetology International. 14: 21-31. PMID 36636157 DOI: 10.1007/s13340-022-00600-2 |
0.354 |
|
| 2022 |
Kitamoto T, Lee YK, Sultana N, Watanabe H, M WM, Du W, Fan J, Diaz B, Lin HV, Leibel RL, Belvedere S, Accili D. Chemical induction of gut β-like-cells by combined FoxO1/Notch inhibition as a glucose-lowering treatment for diabetes. Molecular Metabolism. 101624. PMID 36341906 DOI: 10.1016/j.molmet.2022.101624 |
0.419 |
|
| 2022 |
Lee YK, Du W, Nie Y, Diaz B, Sultana N, Kitamoto T, Leibel RL, Accili D, Belvedere S. Single-agent FOXO1 inhibition normalizes glycemia and induces gut β-like cells in streptozotocin-diabetic mice. Molecular Metabolism. 101618. PMID 36283677 DOI: 10.1016/j.molmet.2022.101618 |
0.476 |
|
| 2022 |
Du W, Wang J, Kuo T, Wang L, McKimpson WM, Son J, Watanabe H, Kitamoto T, Lee YK, Creusot RJ, Ratner LE, McCune K, Chen YW, Grubbs BH, Thornton ME, ... ... Accili D, et al. Pharmacological conversion of gut epithelial cells into insulin-producing cells lowers glycemia in diabetic animals. The Journal of Clinical Investigation. PMID 36282594 DOI: 10.1172/JCI162720 |
0.505 |
|
| 2022 |
Sasako T, Umehara T, Soeda K, Kaneko K, Suzuki M, Kobayashi N, Okazaki Y, Tamura-Nakano M, Chiba T, Accili D, Kahn CR, Noda T, Asahara H, Yamauchi T, Kadowaki T, et al. Deletion of skeletal muscle Akt1/2 causes osteosarcopenia and reduces lifespan in mice. Nature Communications. 13: 5655. PMID 36198696 DOI: 10.1038/s41467-022-33008-2 |
0.378 |
|
| 2022 |
Park J, Li J, Mayer JP, Ball KA, Wu J, Hall C, Accili D, Stowell MHB, Bai XC, Choi E. Activation of the insulin receptor by an insulin mimetic peptide. Nature Communications. 13: 5594. PMID 36151101 DOI: 10.1038/s41467-022-33274-0 |
0.445 |
|
| 2022 |
McKimpson WM, Kuo T, Kitamoto T, Higuchi S, Mills JC, Haeusler RA, Accili D. FOXO1 Is Present in Stomach Epithelium and Determines Gastric Cell Distribution. Gastro Hep Advances. 1: 733-745. PMID 36117550 DOI: 10.1016/j.gastha.2022.05.005 |
0.387 |
|
| 2022 |
Bartolomé A, Suda N, Yu J, Zhu C, Son J, Ding H, Califano A, Accili D, Pajvani UB. Notch-mediated Ephrin signaling disrupts islet architecture and β cell function. Jci Insight. PMID 35167496 DOI: 10.1172/jci.insight.157694 |
0.371 |
|
| 2021 |
Wang L, Yu J, Zhou Q, Wang X, Mukhanova M, Du W, Sun L, Pajvani UB, Accili D. TOX4, an insulin receptor-independent regulator of hepatic glucose production, is activated in diabetic liver. Cell Metabolism. PMID 34914893 DOI: 10.1016/j.cmet.2021.11.013 |
0.473 |
|
| 2021 |
Son J, Ding H, Farb TB, Efanov AM, Sun J, Gore JL, Syed SK, Lei Z, Wang Q, Accili D, Califano A. BACH2 inhibition reverses β cell failure in type 2 diabetes models. The Journal of Clinical Investigation. 131. PMID 34907913 DOI: 10.1172/JCI153876 |
0.481 |
|
| 2021 |
Miyachi Y, Kuo T, Son J, Accili D. Aldo-ketoreductase 1c19 ablation does not affect insulin secretion in murine islets. Plos One. 16: e0260526. PMID 34843575 DOI: 10.1371/journal.pone.0260526 |
0.398 |
|
| 2021 |
Kitamoto T, Kuo T, Okabe A, Kaneda A, Accili D. An integrative transcriptional logic model of hepatic insulin resistance. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34732569 DOI: 10.1073/pnas.2102222118 |
0.46 |
|
| 2021 |
Lambie M, Bonomini M, Davies SJ, Accili D, Arduini A, Zammit V. Insulin resistance in cardiovascular disease, uremia, and peritoneal dialysis. Trends in Endocrinology and Metabolism: Tem. PMID 34266706 DOI: 10.1016/j.tem.2021.06.001 |
0.349 |
|
| 2021 |
Nalbandian A, Sehgal K, Gupta A, Madhavan MV, McGroder C, Stevens JS, Cook JR, Nordvig AS, Shalev D, Sehrawat TS, Ahluwalia N, Bikdeli B, Dietz D, Der-Nigoghossian C, Liyanage-Don N, ... ... Accili D, et al. Post-acute COVID-19 syndrome. Nature Medicine. PMID 33753937 DOI: 10.1038/s41591-021-01283-z |
0.67 |
|
| 2021 |
Lee YK, Diaz B, Deroose M, Lee SX, Belvedere S, Accili D, Leibel RL, Lin HV. FOXO1 inhibition synergizes with FGF21 to normalize glucose control in diabetic mice. Molecular Metabolism. 101187. PMID 33577983 DOI: 10.1016/j.molmet.2021.101187 |
0.314 |
|
| 2020 |
Toda G, Soeda K, Okazaki Y, Kobayashi N, Masuda Y, Arakawa N, Suwanai H, Masamoto Y, Izumida Y, Kamei N, Sasako T, Suzuki R, Kubota T, Kubota N, Kurokawa M, ... ... Accili D, et al. Insulin- and Lipopolysaccharide-Mediated Signaling in Adipose Tissue Macrophages Regulates Postprandial Glycemia through Akt-mTOR Activation. Molecular Cell. PMID 32464093 DOI: 10.1016/J.Molcel.2020.04.033 |
0.523 |
|
| 2020 |
Liu L, Fan L, Chan M, Kraakman MJ, Yang J, Fan Y, Aaron N, Wan Q, Carrillo-Sepulveda MA, Tall AR, Tabas I, Accili D, Qiang L. PPARγ Deacetylation Confers the Anti-Atherogenic Effect and Improves Endothelial Function in Diabetes Treatment. Diabetes. PMID 32409492 DOI: 10.2337/Db20-0217 |
0.452 |
|
| 2020 |
Hosooka T, Hosokawa Y, Matsugi K, Shinohara M, Senga Y, Tamori Y, Aoki C, Matsui S, Sasaki T, Kitamura T, Kuroda M, Sakaue H, Nomura K, Yoshino K, Nabatame Y, ... ... Accili D, et al. The PDK1-FoxO1 signaling in adipocytes controls systemic insulin sensitivity through the 5-lipoxygenase-leukotriene B axis. Proceedings of the National Academy of Sciences of the United States of America. PMID 32393635 DOI: 10.1073/Pnas.1921015117 |
0.544 |
|
| 2020 |
Fan J, Du W, Kim-Muller JY, Son J, Kuo T, Larrea D, Garcia C, Kitamoto T, Kraakman MJ, Owusu-Ansah E, Cirulli V, Accili D. Cyb5r3 links FoxO1-dependent mitochondrial dysfunction with β-cell failure. Molecular Metabolism. 34: 97-111. PMID 32180563 DOI: 10.1016/J.Molmet.2019.12.008 |
0.354 |
|
| 2020 |
Kuo T, Accili D. 2071-P: C2CD4A, Pancreatic Beta-Cell Function, and Type 2 Diabetes Susceptibility Diabetes. 69. DOI: 10.2337/Db20-2071-P |
0.366 |
|
| 2020 |
McKimpson WM, Kuo T, Kitamoto T, Higuchi S, Haeusler R, Accili D. SUN-646 A Novel Population of FOXO1-Expressing Cells in the Stomach Controls Cell Plasticity by Regulating the Cyclin CCNE1 Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.528 |
0.496 |
|
| 2019 |
Kuo T, Kraakman MJ, Damle M, Gill R, Lazar MA, Accili D. Identification of as a human diabetes susceptibility gene with a role in β cell insulin secretion. Proceedings of the National Academy of Sciences of the United States of America. PMID 31527256 DOI: 10.1073/Pnas.1904311116 |
0.458 |
|
| 2019 |
Ren H, Vieira-de-Abreu A, Yan S, Reilly AM, Chan O, Accili D. Altered Central Nutrient Sensing in Male Mice Lacking Insulin Receptors in Glut4-expressing Neurons. Endocrinology. PMID 31199472 DOI: 10.1210/En.2019-00341 |
0.496 |
|
| 2019 |
McKimpson WM, Accili D. Reprogramming Cells to Make Insulin. Journal of the Endocrine Society. 3: 1214-1226. PMID 31187080 DOI: 10.1210/Js.2019-00040 |
0.569 |
|
| 2019 |
Kuo T, Damle M, González BJ, Egli D, Lazar MA, Accili D. Induction of α cell-restricted Gc in dedifferentiating β cells contributes to stress-induced β-cell dysfunction. Jci Insight. 5. PMID 31120862 DOI: 10.1172/Jci.Insight.128351 |
0.45 |
|
| 2019 |
McKimpson WM, Accili D. A Fluorescent Reporter Assay of Differential Gene Expression Response to Insulin in Hepatocytes. American Journal of Physiology. Cell Physiology. PMID 31091147 DOI: 10.1152/Ajpcell.00504.2018 |
0.542 |
|
| 2019 |
Wang L, Liu Q, Kitamoto T, Hou J, Qin J, Accili D. Identification of Insulin-Responsive Transcription Factors Regulating Hepatocyte Glucose Production. Diabetes. PMID 30936148 DOI: 10.2337/Db18-1236 |
0.546 |
|
| 2018 |
Langlet F, Tarbier M, Haeusler RA, Camastra S, Ferrannini E, Friedländer MR, Accili D. microRNA-205-5p is a modulator of insulin sensitivity that inhibits FOXO function. Molecular Metabolism. PMID 30174230 DOI: 10.1016/J.Molmet.2018.08.003 |
0.548 |
|
| 2018 |
Accili D. Insulin Action Research and the Future of Diabetes Treatment: The 2017 Banting Medal for Scientific Achievement Lecture. Diabetes. 67: 1701-1709. PMID 30135131 DOI: 10.2337/Dbi18-0025 |
0.557 |
|
| 2018 |
Kitamoto T, Sakurai K, Lee EY, Yokote K, Accili D, Miki T. Distinct roles of systemic and local actions of insulin on pancreatic β-cells. Metabolism: Clinical and Experimental. PMID 29320716 DOI: 10.1016/J.Metabol.2017.12.017 |
0.415 |
|
| 2018 |
MCKIMPSON W, KUO T, ACCILI D. Foxo1-Expressing Cells in the Gut as a Source of Insulin for Diabetes Treatment Diabetes. 67: 324-OR. DOI: 10.2337/Db18-324-Or |
0.529 |
|
| 2018 |
CINTI F, SEVERI I, SULEIMAN M, MARSELLI L, MARCHETTI P, CINTI S, ACCILI D. The Increment of Noradrenergic Fibers Correlates with the Density of Dedifferentiated ß Cells in Humans Diabetes. 67: 2142-P. DOI: 10.2337/Db18-2142-P |
0.359 |
|
| 2017 |
Caruso M, Miele C, Oliva A, Condorelli G, Oriente F, Riccardi G, Capaldo B, Fiory F, Accili D, Formisano P, Beguinot F. Expression of Concern. The IR1152 Mutant Insulin Receptor Selectively Impairs Insulin Action in Skeletal Muscle but Not in Liver. Diabetes 2000;49:1194-1202. DOI: https://doi.org/10.2337/diabetes.49.7.1194. PMID: 10909978. Diabetes. PMID 29109243 DOI: 10.2337/Db17-Ec2017A |
0.42 |
|
| 2017 |
Langlet F, Haeusler RA, Lindén D, Ericson E, Norris T, Johansson A, Cook JR, Aizawa K, Wang L, Buettner C, Accili D. Selective Inhibition of FOXO1 Activator/Repressor Balance Modulates Hepatic Glucose Handling. Cell. PMID 29056338 DOI: 10.1016/J.Cell.2017.09.045 |
0.805 |
|
| 2017 |
Haeusler RA, McGraw TE, Accili D. Biochemical and cellular properties of insulin receptor signalling. Nature Reviews. Molecular Cell Biology. PMID 28974775 DOI: 10.1038/Nrm.2017.89 |
0.585 |
|
| 2017 |
Ishida E, Kim-Muller JY, Accili D. Pair-Feeding, but not Insulin, Phloridzin, or Rosiglitazone Treatment Curtails Markers of Beta-cell Dedifferentiation in db/db Mice. Diabetes. PMID 28506962 DOI: 10.2337/Db16-1213 |
0.524 |
|
| 2016 |
Accili D, Talchai SC, Kim-Muller JY, Cinti F, Ishida E, Ordelheide AM, Kuo T, Fan J, Son J. When β-cells fail: lessons from dedifferentiation. Diabetes, Obesity & Metabolism. 18: 117-22. PMID 27615140 DOI: 10.1111/Dom.12723 |
0.482 |
|
| 2016 |
Kim-Muller JY, Fan J, Kim YJ, Lee SA, Ishida E, Blaner WS, Accili D. Aldehyde dehydrogenase 1a3 defines a subset of failing pancreatic β cells in diabetic mice. Nature Communications. 7: 12631. PMID 27572106 DOI: 10.1038/Ncomms12631 |
0.476 |
|
| 2016 |
O'Neill BT, Lee KY, Klaus K, Softic S, Krumpoch MT, Fentz J, Stanford KI, Robinson MM, Cai W, Kleinridders A, Pereira RO, Hirshman MF, Abel ED, Accili D, Goodyear LJ, et al. Insulin and IGF-1 receptors regulate FoxO-mediated signaling in muscle proteostasis. The Journal of Clinical Investigation. PMID 27525440 DOI: 10.1172/Jci86522 |
0.368 |
|
| 2016 |
Vazirani RP, Verma A, Sadacca LA, Buckman MS, Picatoste B, Beg M, Torsitano C, Bruno JH, Patel RT, Simonyte K, Camporez JP, Moreira G, Falcone DJ, Accili D, Elemento O, et al. Disruption of Adipose Rab10-Dependent Insulin Signaling Causes Hepatic Insulin Resistance. Diabetes. PMID 27207531 DOI: 10.2337/db15-1128 |
0.465 |
|
| 2016 |
Kim-Muller JY, Kim YJ, Fan J, Zhao S, Banks AS, Prentki M, Accili D. FoxO1 Deacetylation Decreases Fatty Acid Oxidation in beta-cells and Sustains Insulin Secretion in Diabetes. The Journal of Biological Chemistry. PMID 26984405 DOI: 10.1074/Jbc.M115.705608 |
0.47 |
|
| 2016 |
Kuo T, Kim-Muller JY, McGraw TE, Accili D. Altered Plasma Profile of Antioxidant Proteins as an Early Correlate of Pancreatic β Cell Dysfunction. The Journal of Biological Chemistry. PMID 26917725 DOI: 10.1074/Jbc.M115.702183 |
0.544 |
|
| 2016 |
Cinti F, Bouchi R, Kim-Muller JY, Ohmura Y, Sandoval PR, Masini M, Marselli L, Suleiman M, Ratner LE, Marchetti P, Accili D. Evidence of β-Cell Dedifferentiation in Human Type 2 Diabetes. The Journal of Clinical Endocrinology and Metabolism. 101: 1044-54. PMID 26713822 DOI: 10.1210/Jc.2015-2860 |
0.449 |
|
| 2015 |
Abraham A, Rubin M, Accili D, Bilezikian JP, Pajvani UB. Hypoglycemia Secondary to Sulfonylurea Ingestion in a Patient with End Stage Renal Disease: Results from a 72-Hour Fast. Case Reports in Endocrinology. 2015: 742781. PMID 26664768 DOI: 10.1155/2015/742781 |
0.425 |
|
| 2015 |
Pajvani UB, Accili D. The new biology of diabetes. Diabetologia. 58: 2459-68. PMID 26248647 DOI: 10.1007/s00125-015-3722-5 |
0.415 |
|
| 2015 |
Ren H, Cook JR, Kon N, Accili D. Gpr17 in AgRP Neurons Regulates Feeding and Sensitivity to Insulin and Leptin. Diabetes. 64: 3670-9. PMID 26180086 DOI: 10.2337/Db15-0390 |
0.768 |
|
| 2015 |
Qiang L, Kon N, Zhao W, Jiang L, Knight CM, Welch C, Pajvani U, Gu W, Accili D. Hepatic SirT1-Dependent Gain of Function of Stearoyl-CoA Desaturase-1 Conveys Dysmetabolic and Tumor Progression Functions. Cell Reports. 11: 1797-808. PMID 26074075 DOI: 10.1016/J.Celrep.2015.05.025 |
0.337 |
|
| 2015 |
Mayoral R, Osborn O, McNelis J, Johnson AM, Oh da Y, Izquierdo CL, Chung H, Li P, Traves PG, Bandyopadhyay G, Pessentheiner AR, Ofrecio JM, Cook JR, Qiang L, Accili D, et al. Adipocyte SIRT1 knockout promotes PPARγ activity, adipogenesis and insulin sensitivity in chronic-HFD and obesity. Molecular Metabolism. 4: 378-91. PMID 25973386 DOI: 10.1016/J.Molmet.2015.02.007 |
0.754 |
|
| 2015 |
Cook JR, Langlet F, Kido Y, Accili D. Pathogenesis of selective insulin resistance in isolated hepatocytes. The Journal of Biological Chemistry. 290: 13972-80. PMID 25873396 DOI: 10.1074/Jbc.M115.638197 |
0.815 |
|
| 2015 |
Talchai SC, Accili D. Legacy Effect of Foxo1 in Pancreatic Endocrine Progenitors on Adult β-Cell Mass and Function. Diabetes. 64: 2868-79. PMID 25784544 DOI: 10.2337/Db14-1696 |
0.425 |
|
| 2015 |
Cook JR, Matsumoto M, Banks AS, Kitamura T, Tsuchiya K, Accili D. A Mutant Allele Encoding DNA Binding-Deficient FoxO1 Differentially Regulates Hepatic Glucose and Lipid Metabolism. Diabetes. 64: 1951-65. PMID 25576059 DOI: 10.2337/Db14-1506 |
0.785 |
|
| 2015 |
Ren H, Lu TY, McGraw TE, Accili D. Anorexia and impaired glucose metabolism in mice with hypothalamic ablation of Glut4 neurons. Diabetes. 64: 405-17. PMID 25187366 DOI: 10.2337/Db14-0752 |
0.439 |
|
| 2014 |
Haeusler RA, Hartil K, Vaitheesvaran B, Arrieta-Cruz I, Knight CM, Cook JR, Kammoun HL, Febbraio MA, Gutierrez-Juarez R, Kurland IJ, Accili D. Integrated control of hepatic lipogenesis versus glucose production requires FoxO transcription factors. Nature Communications. 5: 5190. PMID 25307742 DOI: 10.1038/Ncomms6190 |
0.798 |
|
| 2014 |
Kim-Muller JY, Zhao S, Srivastava S, Mugabo Y, Noh HL, Kim YR, Madiraju SR, Ferrante AW, Skolnik EY, Prentki M, Accili D. Metabolic inflexibility impairs insulin secretion and results in MODY-like diabetes in triple FoxO-deficient mice. Cell Metabolism. 20: 593-602. PMID 25264246 DOI: 10.1016/J.Cmet.2014.08.012 |
0.51 |
|
| 2014 |
Bouchi R, Foo KS, Hua H, Tsuchiya K, Ohmura Y, Sandoval PR, Ratner LE, Egli D, Leibel RL, Accili D. FOXO1 inhibition yields functional insulin-producing cells in human gut organoid cultures. Nature Communications. 5: 4242. PMID 24979718 DOI: 10.1038/Ncomms5242 |
0.557 |
|
| 2014 |
Ren H, Yan S, Zhang B, Lu TY, Arancio O, Accili D. Glut4 expression defines an insulin-sensitive hypothalamic neuronal population. Molecular Metabolism. 3: 452-9. PMID 24944904 DOI: 10.1016/J.Molmet.2014.04.006 |
0.484 |
|
| 2014 |
Heinrich G, Meece K, Wardlaw SL, Accili D. Preserved energy balance in mice lacking FoxO1 in neurons of Nkx2.1 lineage reveals functional heterogeneity of FoxO1 signaling within the hypothalamus. Diabetes. 63: 1572-82. PMID 24487022 DOI: 10.2337/Db13-0651 |
0.329 |
|
| 2014 |
Giannulis I, Mondini E, Cinti F, Frontini A, Murano I, Barazzoni R, Barbatelli G, Accili D, Cinti S. Increased density of inhibitory noradrenergic parenchymal nerve fibers in hypertrophic islets of Langerhans of obese mice. Nutrition Metabolism and Cardiovascular Diseases. 24: 384-392. PMID 24462047 DOI: 10.1016/J.Numecd.2013.09.006 |
0.49 |
|
| 2013 |
Haeusler RA, Astiarraga B, Camastra S, Accili D, Ferrannini E. Human insulin resistance is associated with increased plasma levels of 12α-hydroxylated bile acids. Diabetes. 62: 4184-91. PMID 23884887 DOI: 10.2337/Db13-0639 |
0.486 |
|
| 2013 |
Ren H, Plum-Morschel L, Gutierrez-Juarez R, Lu TY, Kim-Muller JY, Heinrich G, Wardlaw SL, Silver R, Accili D. Blunted refeeding response and increased locomotor activity in mice lacking FoxO1 in synapsin-Cre-expressing neurons. Diabetes. 62: 3373-83. PMID 23835335 DOI: 10.2337/Db13-0597 |
0.382 |
|
| 2013 |
Pajvani UB, Qiang L, Kangsamaksin T, Kitajewski J, Ginsberg HN, Accili D. Inhibition of Notch uncouples Akt activation from hepatic lipid accumulation by decreasing mTorc1 stability. Nature Medicine. 19: 1054-60. PMID 23832089 DOI: 10.1038/Nm.3259 |
0.375 |
|
| 2013 |
Kurland IJ, Accili D, Burant C, Fischer SM, Kahn BB, Newgard CB, Ramagiri S, Ronnett GV, Ryals JA, Sanders M, Shambaugh J, Shockcor J, Gross SS. Application of combined omics platforms to accelerate biomedical discovery in diabesity. Annals of the New York Academy of Sciences. 1287: 1-16. PMID 23659636 DOI: 10.1111/Nyas.12116 |
0.312 |
|
| 2013 |
Tsuchiya K, Westerterp M, Murphy AJ, Subramanian V, Ferrante AW, Tall AR, Accili D. Expanded granulocyte/monocyte compartment in myeloid-specific triple FoxO knockout increases oxidative stress and accelerates atherosclerosis in mice. Circulation Research. 112: 992-1003. PMID 23420833 DOI: 10.1161/Circresaha.112.300749 |
0.409 |
|
| 2013 |
Fiorentino L, Cavalera M, Menini S, Marchetti V, Mavilio M, Fabrizi M, Conserva F, Casagrande V, Menghini R, Pontrelli P, Arisi I, D'Onofrio M, Lauro D, Khokha R, Accili D, et al. Loss of TIMP3 underlies diabetic nephropathy via FoxO1/STAT1 interplay. Embo Molecular Medicine. 5: 441-55. PMID 23401241 DOI: 10.1002/Emmm.201201475 |
0.356 |
|
| 2013 |
Tsuchiya K, Accili D. Liver sinusoidal endothelial cells link hyperinsulinemia to hepatic insulin resistance. Diabetes. 62: 1478-89. PMID 23349480 DOI: 10.2337/Db12-1296 |
0.568 |
|
| 2012 |
Ido-Kitamura Y, Sasaki T, Kobayashi M, Kim HJ, Lee YS, Kikuchi O, Yokota-Hashimoto H, Iizuka K, Accili D, Kitamura T. Hepatic FoxO1 integrates glucose utilization and lipid synthesis through regulation of Chrebp O-glycosylation. Plos One. 7: e47231. PMID 23056614 DOI: 10.1371/Journal.Pone.0047231 |
0.461 |
|
| 2012 |
Talchai C, Xuan S, Lin HV, Sussel L, Accili D. Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure. Cell. 150: 1223-34. PMID 22980982 DOI: 10.1016/J.Cell.2012.07.029 |
0.728 |
|
| 2012 |
Boitard C, Accili D, Ahrén B, Cerasi E, Seino S, Thorens B. The hyperstimulated β-cell: prelude to diabetes? Diabetes, Obesity & Metabolism. 14: iv-viii. PMID 22928578 DOI: 10.1111/J.1463-1326.2012.01693.X |
0.37 |
|
| 2012 |
Qiang L, Wang L, Kon N, Zhao W, Lee S, Zhang Y, Rosenbaum M, Zhao Y, Gu W, Farmer SR, Accili D. Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Pparγ. Cell. 150: 620-32. PMID 22863012 DOI: 10.1016/J.Cell.2012.06.027 |
0.369 |
|
| 2012 |
Ozcan L, Wong CC, Li G, Xu T, Pajvani U, Park SK, Wronska A, Chen BX, Marks AR, Fukamizu A, Backs J, Singer HA, Yates JR, Accili D, Tabas I. Calcium signaling through CaMKII regulates hepatic glucose production in fasting and obesity. Cell Metabolism. 15: 739-51. PMID 22503562 DOI: 10.1016/J.Cmet.2012.03.002 |
0.411 |
|
| 2012 |
Ai D, Chen C, Han S, Ganda A, Murphy AJ, Haeusler R, Thorp E, Accili D, Horton JD, Tall AR. Regulation of hepatic LDL receptors by mTORC1 and PCSK9 in mice. The Journal of Clinical Investigation. 122: 1262-70. PMID 22426206 DOI: 10.1172/Jci61919 |
0.433 |
|
| 2012 |
Talchai C, Xuan S, Kitamura T, DePinho RA, Accili D. Generation of functional insulin-producing cells in the gut by Foxo1 ablation. Nature Genetics. 44: 406-12, S1. PMID 22406641 DOI: 10.1038/Ng.2215 |
0.809 |
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| 2012 |
Tsuchiya K, Tanaka J, Shuiqing Y, Welch CL, DePinho RA, Tabas I, Tall AR, Goldberg IJ, Accili D. FoxOs integrate pleiotropic actions of insulin in vascular endothelium to protect mice from atherosclerosis. Cell Metabolism. 15: 372-81. PMID 22405072 DOI: 10.1016/J.Cmet.2012.01.018 |
0.51 |
|
| 2012 |
Qiang L, Tsuchiya K, Kim-Muller JY, Lin HV, Welch C, Accili D. Increased atherosclerosis and endothelial dysfunction in mice bearing constitutively deacetylated alleles of Foxo1 gene. The Journal of Biological Chemistry. 287: 13944-51. PMID 22389493 DOI: 10.1074/Jbc.M111.332767 |
0.428 |
|
| 2012 |
Qiang L, Accili D. FGF21 and the second coming of PPARγ. Cell. 148: 397-8. PMID 22304910 DOI: 10.1016/J.Cell.2012.01.020 |
0.335 |
|
| 2012 |
Haeusler RA, Pratt-Hyatt M, Welch CL, Klaassen CD, Accili D. Impaired generation of 12-hydroxylated bile acids links hepatic insulin signaling with dyslipidemia. Cell Metabolism. 15: 65-74. PMID 22197325 DOI: 10.1016/J.Cmet.2011.11.010 |
0.443 |
|
| 2012 |
Kon N, Zhong J, Qiang L, Accili D, Gu W. Inactivation of arf-bp1 induces p53 activation and diabetic phenotypes in mice. The Journal of Biological Chemistry. 287: 5102-11. PMID 22187431 DOI: 10.1074/Jbc.M111.322867 |
0.351 |
|
| 2012 |
Accili D. Insulin receptor knock-out mice. Trends in Endocrinology and Metabolism: Tem. 8: 101-4. PMID 18406794 DOI: 10.1016/S1043-2760(97)00031-3 |
0.47 |
|
| 2012 |
Atkinson MA, Bluestone JA, Eisenbarth GS, Hebrok M, Herold KC, Accili D, Pietropaolo M, Arvan PR, Von Herrath M, Markel DS, Rhodes CJ. How does type 1 diabetes develop? The notion of homicide or β-cell suicide revisited (Diabetes (2011) 60, (1370-1379)) Diabetes. 61: 1648. DOI: 10.2337/Db12-Er06A |
0.384 |
|
| 2011 |
Qiang L, Lin HV, Kim-Muller JY, Welch CL, Gu W, Accili D. Proatherogenic abnormalities of lipid metabolism in SirT1 transgenic mice are mediated through Creb deacetylation. Cell Metabolism. 14: 758-67. PMID 22078933 DOI: 10.1016/J.Cmet.2011.10.007 |
0.519 |
|
| 2011 |
Banks AS, Kim-Muller JY, Mastracci TL, Kofler NM, Qiang L, Haeusler RA, Jurczak MJ, Laznik D, Heinrich G, Samuel VT, Shulman GI, Papaioannou VE, Accili D. Dissociation of the glucose and lipid regulatory functions of FoxO1 by targeted knockin of acetylation-defective alleles in mice. Cell Metabolism. 14: 587-97. PMID 22055502 DOI: 10.1016/J.Cmet.2011.09.012 |
0.514 |
|
| 2011 |
Tsuchiya K, Banks AS, Liang CP, Tabas I, Tall AR, Accili D. Homozygosity for an allele encoding deacetylated FoxO1 protects macrophages from cholesterol-induced inflammation without increasing apoptosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 2920-8. PMID 21940942 DOI: 10.1161/Atvbaha.110.219477 |
0.347 |
|
| 2011 |
Tsunekawa S, Demozay D, Briaud I, McCuaig J, Accili D, Stein R, Rhodes CJ. FoxO feedback control of basal IRS-2 expression in pancreatic β-cells is distinct from that in hepatocytes. Diabetes. 60: 2883-91. PMID 21933986 DOI: 10.2337/Db11-0340 |
0.499 |
|
| 2011 |
Pajvani UB, Shawber CJ, Samuel VT, Birkenfeld AL, Shulman GI, Kitajewski J, Accili D. Inhibition of Notch signaling ameliorates insulin resistance in a FoxO1-dependent manner. Nature Medicine. 17: 961-7. PMID 21804540 DOI: 10.1038/Nm.2378 |
0.578 |
|
| 2011 |
Lin HV, Accili D. Hormonal regulation of hepatic glucose production in health and disease. Cell Metabolism. 14: 9-19. PMID 21723500 DOI: 10.1016/J.Cmet.2011.06.003 |
0.429 |
|
| 2011 |
Gonzalez E, Flier E, Molle D, Accili D, McGraw TE. Hyperinsulinemia leads to uncoupled insulin regulation of the GLUT4 glucose transporter and the FoxO1 transcription factor. Proceedings of the National Academy of Sciences of the United States of America. 108: 10162-7. PMID 21646544 DOI: 10.1073/Pnas.1019268108 |
0.574 |
|
| 2011 |
Atkinson MA, Bluestone JA, Eisenbarth GS, Hebrok M, Herold KC, Accili D, Pietropaolo M, Arvan PR, Von Herrath M, Markel DS, Rhodes CJ. How does type 1 diabetes develop?: the notion of homicide or β-cell suicide revisited. Diabetes. 60: 1370-9. PMID 21525508 DOI: 10.2337/Db10-1797 |
0.396 |
|
| 2011 |
Kim-Muller JY, Accili D. Cell biology. Selective insulin sensitizers. Science (New York, N.Y.). 331: 1529-31. PMID 21436429 DOI: 10.1126/Science.1204504 |
0.578 |
|
| 2011 |
Lin HV, Ren H, Samuel VT, Lee HY, Lu TY, Shulman GI, Accili D. Diabetes in mice with selective impairment of insulin action in Glut4-expressing tissues. Diabetes. 60: 700-9. PMID 21266328 DOI: 10.2337/Db10-1056 |
0.57 |
|
| 2011 |
Lin HV, Accili D. Reconstitution of insulin action in muscle, white adipose tissue, and brain of insulin receptor knock-out mice fails to rescue diabetes. The Journal of Biological Chemistry. 286: 9797-804. PMID 21239487 DOI: 10.1074/Jbc.M110.210807 |
0.589 |
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| 2011 |
Accili D, Ahrén B, Boitard C, Cerasi E, Henquin JC, Seino S. What ails the β-cell? Diabetes, Obesity & Metabolism. 1-3. PMID 21029293 DOI: 10.1111/J.1463-1326.2010.01296.X |
0.305 |
|
| 2011 |
Carmody JS, Wan P, Accili D, Zeltser LM, Leibel RL. Respective contributions of maternal insulin resistance and diet to metabolic and hypothalamic phenotypes of progeny. Obesity (Silver Spring, Md.). 19: 492-9. PMID 20948526 DOI: 10.1038/Oby.2010.245 |
0.408 |
|
| 2010 |
Xuan S, Szabolcs M, Cinti F, Perincheri S, Accili D, Efstratiadis A. Genetic analysis of type-1 insulin-like growth factor receptor signaling through insulin receptor substrate-1 and -2 in pancreatic beta cells. The Journal of Biological Chemistry. 285: 41044-50. PMID 20947509 DOI: 10.1074/Jbc.M110.144790 |
0.552 |
|
| 2010 |
Chang CL, Seo T, Du CB, Accili D, Deckelbaum RJ. n-3 Fatty acids decrease arterial low-density lipoprotein cholesterol delivery and lipoprotein lipase levels in insulin-resistant mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 2510-7. PMID 20930167 DOI: 10.1161/Atvbaha.110.215848 |
0.381 |
|
| 2010 |
Haeusler RA, Kaestner KH, Accili D. FoxOs function synergistically to promote glucose production. The Journal of Biological Chemistry. 285: 35245-8. PMID 20880840 DOI: 10.1074/Jbc.C110.175851 |
0.505 |
|
| 2010 |
Haeusler RA, Han S, Accili D. Hepatic FoxO1 ablation exacerbates lipid abnormalities during hyperglycemia. The Journal of Biological Chemistry. 285: 26861-8. PMID 20573950 DOI: 10.1074/Jbc.M110.134023 |
0.466 |
|
| 2010 |
Qiang L, Banks AS, Accili D. Uncoupling of acetylation from phosphorylation regulates FoxO1 function independent of its subcellular localization. The Journal of Biological Chemistry. 285: 27396-401. PMID 20519497 DOI: 10.1074/Jbc.M110.140228 |
0.32 |
|
| 2010 |
Ren H, Accili D, Duan C. Hypoxia converts the myogenic action of insulin-like growth factors into mitogenic action by differentially regulating multiple signaling pathways. Proceedings of the National Academy of Sciences of the United States of America. 107: 5857-62. PMID 20231451 DOI: 10.1073/Pnas.0909570107 |
0.384 |
|
| 2010 |
Nandi A, Wang X, Accili D, Wolgemuth DJ. The effect of insulin signaling on female reproductive function independent of adiposity and hyperglycemia. Endocrinology. 151: 1863-71. PMID 20176725 DOI: 10.1210/En.2009-0788 |
0.438 |
|
| 2010 |
Tabas I, Tall A, Accili D. The impact of macrophage insulin resistance on advanced atherosclerotic plaque progression. Circulation Research. 106: 58-67. PMID 20056946 DOI: 10.1161/Circresaha.109.208488 |
0.506 |
|
| 2010 |
Lin HV, Plum L, Ono H, Gutiérrez-Juárez R, Shanabrough M, Borok E, Horvath TL, Rossetti L, Accili D. Divergent regulation of energy expenditure and hepatic glucose production by insulin receptor in agouti-related protein and POMC neurons. Diabetes. 59: 337-46. PMID 19933998 DOI: 10.2337/Db09-1303 |
0.517 |
|
| 2009 |
Talchai C, Lin HV, Kitamura T, Accili D. Genetic and biochemical pathways of beta-cell failure in type 2 diabetes. Diabetes, Obesity & Metabolism. 11: 38-45. PMID 19817787 DOI: 10.1111/J.1463-1326.2009.01115.X |
0.784 |
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| 2009 |
Plum L, Lin HV, Dutia R, Tanaka J, Aizawa KS, Matsumoto M, Kim AJ, Cawley NX, Paik JH, Loh YP, DePinho RA, Wardlaw SL, Accili D. The obesity susceptibility gene Cpe links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake. Nature Medicine. 15: 1195-201. PMID 19767734 DOI: 10.1038/Nm.2026 |
0.325 |
|
| 2009 |
Kitamura T, Kitamura YI, Kobayashi M, Kikuchi O, Sasaki T, Depinho RA, Accili D. Regulation of pancreatic juxtaductal endocrine cell formation by FoxO1. Molecular and Cellular Biology. 29: 4417-30. PMID 19506018 DOI: 10.1128/Mcb.01622-08 |
0.432 |
|
| 2009 |
Han S, Liang CP, Westerterp M, Senokuchi T, Welch CL, Wang Q, Matsumoto M, Accili D, Tall AR. Hepatic insulin signaling regulates VLDL secretion and atherogenesis in mice. The Journal of Clinical Investigation. 119: 1029-41. PMID 19273907 DOI: 10.1172/Jci36523 |
0.467 |
|
| 2009 |
Accili D, Cola GD, Young Lee C, Cool MH. S-3: Metabolic abnormalities in mice lacking insulin receptors Experimental and Clinical Endocrinology & Diabetes. 104: 3-4. DOI: 10.1055/s-0029-1211489 |
0.368 |
|
| 2008 |
Banks AS, Kon N, Knight C, Matsumoto M, Gutiérrez-Juárez R, Rossetti L, Gu W, Accili D. SirT1 gain of function increases energy efficiency and prevents diabetes in mice. Cell Metabolism. 8: 333-41. PMID 18840364 DOI: 10.1016/J.Cmet.2008.08.014 |
0.53 |
|
| 2008 |
Senokuchi T, Liang CP, Seimon TA, Han S, Matsumoto M, Banks AS, Paik JH, DePinho RA, Accili D, Tabas I, Tall AR. Forkhead transcription factors (FoxOs) promote apoptosis of insulin-resistant macrophages during cholesterol-induced endoplasmic reticulum stress. Diabetes. 57: 2967-76. PMID 18728232 DOI: 10.2337/Db08-0520 |
0.421 |
|
| 2008 |
Haeusler RA, Accili D. The double life of Irs. Cell Metabolism. 8: 7-9. PMID 18590687 DOI: 10.1016/J.Cmet.2008.06.010 |
0.44 |
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| 2008 |
Leroith D, Accili D. Mechanisms of disease: using genetically altered mice to study concepts of type 2 diabetes. Nature Clinical Practice. Endocrinology & Metabolism. 4: 164-72. PMID 18212763 DOI: 10.1038/Ncpendmet0729 |
0.503 |
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| 2008 |
Goldfine ID, Maddux BA, Youngren JF, Reaven G, Accili D, Trischitta V, Vigneri R, Frittitta L. The role of membrane glycoprotein plasma cell antigen 1/ectonucleotide pyrophosphatase phosphodiesterase 1 in the pathogenesis of insulin resistance and related abnormalities. Endocrine Reviews. 29: 62-75. PMID 18199690 DOI: 10.1210/Er.2007-0004 |
0.546 |
|
| 2008 |
Accili D. PL9 Regulation of pancreatic endocrine function by IGF and insulin signalling Growth Hormone & Igf Research. 18: S19. DOI: 10.1016/S1096-6374(08)70062-5 |
0.39 |
|
| 2008 |
Accili D. Mechanisms of β cell failure in the pathogenesis of Type 2 diabetes Drug Development Research. 69: 111-115. DOI: 10.1002/Ddr.20234 |
0.52 |
|
| 2007 |
Tabas I, Seimon T, Arellano J, Li Y, Forcheron F, Cui D, Han S, Liang CP, Tall A, Accili D. The impact of insulin resistance on macrophage death pathways in advanced atherosclerosis. Novartis Foundation Symposium. 286: 99-109; discussion 1. PMID 18269177 DOI: 10.1002/9780470985571.Ch9 |
0.46 |
|
| 2007 |
Matsumoto M, Pocai A, Rossetti L, Depinho RA, Accili D. Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor Foxo1 in liver. Cell Metabolism. 6: 208-16. PMID 17767907 DOI: 10.1016/J.Cmet.2007.08.006 |
0.54 |
|
| 2007 |
Lin HV, Kim JY, Pocai A, Rossetti L, Shapiro L, Scherer PE, Accili D. Adiponectin resistance exacerbates insulin resistance in insulin receptor transgenic/knockout mice. Diabetes. 56: 1969-76. PMID 17475934 DOI: 10.2337/Db07-0127 |
0.559 |
|
| 2007 |
Adachi M, Osawa Y, Uchinami H, Kitamura T, Accili D, Brenner DA. The forkhead transcription factor FoxO1 regulates proliferation and transdifferentiation of hepatic stellate cells. Gastroenterology. 132: 1434-46. PMID 17408630 DOI: 10.1053/J.Gastro.2007.01.033 |
0.328 |
|
| 2007 |
Naïmi M, Gautier N, Chaussade C, Valverde AM, Accili D, Van Obberghen E. Nuclear forkhead box O1 controls and integrates key signaling pathways in hepatocytes. Endocrinology. 148: 2424-34. PMID 17303659 DOI: 10.1210/En.2006-1411 |
0.384 |
|
| 2007 |
Kim JJ, Kido Y, Scherer PE, White MF, Accili D. Analysis of compensatory beta-cell response in mice with combined mutations of Insr and Irs2. American Journal of Physiology. Endocrinology and Metabolism. 292: E1694-701. PMID 17299086 DOI: 10.1152/Ajpendo.00430.2006 |
0.532 |
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| 2007 |
Buteau J, Shlien A, Foisy S, Accili D. Metabolic diapause in pancreatic beta-cells expressing a gain-of-function mutant of the forkhead protein Foxo1. The Journal of Biological Chemistry. 282: 287-93. PMID 17107961 DOI: 10.1074/Jbc.M606118200 |
0.456 |
|
| 2006 |
Matsumoto M, Han S, Kitamura T, Accili D. Dual role of transcription factor FoxO1 in controlling hepatic insulin sensitivity and lipid metabolism. The Journal of Clinical Investigation. 116: 2464-72. PMID 16906224 DOI: 10.1172/Jci27047 |
0.539 |
|
| 2006 |
Buteau J, Spatz ML, Accili D. Transcription factor FoxO1 mediates glucagon-like peptide-1 effects on pancreatic beta-cell mass. Diabetes. 55: 1190-6. PMID 16644672 DOI: 10.2337/Db05-0825 |
0.408 |
|
| 2006 |
Han S, Liang CP, DeVries-Seimon T, Ranalletta M, Welch CL, Collins-Fletcher K, Accili D, Tabas I, Tall AR. Macrophage insulin receptor deficiency increases ER stress-induced apoptosis and necrotic core formation in advanced atherosclerotic lesions. Cell Metabolism. 3: 257-66. PMID 16581003 DOI: 10.1016/J.Cmet.2006.02.008 |
0.511 |
|
| 2006 |
Okamoto H, Hribal ML, Lin HV, Bennett WR, Ward A, Accili D. Role of the forkhead protein FoxO1 in beta cell compensation to insulin resistance. The Journal of Clinical Investigation. 116: 775-82. PMID 16485043 DOI: 10.1172/Jci24967 |
0.733 |
|
| 2006 |
Maddux BA, Chang YN, Accili D, McGuinness OP, Youngren JF, Goldfine ID. Overexpression of the insulin receptor inhibitor PC-1/ENPP1 induces insulin resistance and hyperglycemia. American Journal of Physiology. Endocrinology and Metabolism. 290: E746-9. PMID 16278247 DOI: 10.1152/Ajpendo.00298.2005 |
0.556 |
|
| 2005 |
Federici M, Hribal ML, Menghini R, Kanno H, Marchetti V, Porzio O, Sunnarborg SW, Rizza S, Serino M, Cunsolo V, Lauro D, Mauriello A, Smookler DS, Sbraccia P, Sesti G, ... ... Accili D, et al. Timp3 deficiency in insulin receptor-haploinsufficient mice promotes diabetes and vascular inflammation via increased TNF-alpha. The Journal of Clinical Investigation. 115: 3494-505. PMID 16294222 DOI: 10.1172/Jci26052 |
0.502 |
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| 2005 |
Kitamura YI, Kitamura T, Kruse JP, Raum JC, Stein R, Gu W, Accili D. FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction. Cell Metabolism. 2: 153-63. PMID 16154098 DOI: 10.1016/J.Cmet.2005.08.004 |
0.447 |
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| 2005 |
Banks AS, Li J, McKeag L, Hribal ML, Kashiwada M, Accili D, Rothman PB. Deletion of SOCS7 leads to enhanced insulin action and enlarged islets of Langerhans. The Journal of Clinical Investigation. 115: 2462-71. PMID 16127460 DOI: 10.1172/Jci23853 |
0.586 |
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| 2005 |
Matsumoto M, Accili D. All roads lead to FoxO. Cell Metabolism. 1: 215-6. PMID 16054064 DOI: 10.1016/J.Cmet.2005.03.008 |
0.304 |
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| 2005 |
Okamoto H, Obici S, Accili D, Rossetti L. Restoration of liver insulin signaling in Insr knockout mice fails to normalize hepatic insulin action. The Journal of Clinical Investigation. 115: 1314-22. PMID 15864351 DOI: 10.1172/Jci23096 |
0.765 |
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| 2005 |
Frescas D, Valenti L, Accili D. Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genes. The Journal of Biological Chemistry. 280: 20589-95. PMID 15788402 DOI: 10.1074/Jbc.M412357200 |
0.32 |
|
| 2005 |
Dong H, Maddux BA, Altomonte J, Meseck M, Accili D, Terkeltaub R, Johnson K, Youngren JF, Goldfine ID. Increased hepatic levels of the insulin receptor inhibitor, PC-1/NPP1, induce insulin resistance and glucose intolerance. Diabetes. 54: 367-72. PMID 15677494 DOI: 10.2337/Diabetes.54.2.367 |
0.539 |
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| 2004 |
Okamoto H, Nakae J, Kitamura T, Park BC, Dragatsis I, Accili D. Transgenic rescue of insulin receptor-deficient mice. The Journal of Clinical Investigation. 114: 214-23. PMID 15254588 DOI: 10.1172/Jci21645 |
0.772 |
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| 2004 |
Accili D. Lilly lecture 2003: the struggle for mastery in insulin action: from triumvirate to republic. Diabetes. 53: 1633-42. PMID 15220184 DOI: 10.2337/Diabetes.53.7.1633 |
0.596 |
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| 2004 |
Accili D, Arden KC. FoxOs at the crossroads of cellular metabolism, differentiation, and transformation. Cell. 117: 421-6. PMID 15137936 DOI: 10.1016/S0092-8674(04)00452-0 |
0.328 |
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| 2004 |
Tsuchida A, Yamauchi T, Ito Y, Hada Y, Maki T, Takekawa S, Kamon J, Kobayashi M, Suzuki R, Hara K, Kubota N, Terauchi Y, Froguel P, Nakae J, Kasuga M, ... Accili D, et al. Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity. The Journal of Biological Chemistry. 279: 30817-22. PMID 15123605 DOI: 10.1074/Jbc.M402367200 |
0.52 |
|
| 2004 |
Nandi A, Kitamura Y, Kahn CR, Accili D. Mouse models of insulin resistance. Physiological Reviews. 84: 623-47. PMID 15044684 DOI: 10.1152/Physrev.00032.2003 |
0.512 |
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| 2004 |
Kitamura Y, Accili D. New insights into the integrated physiology of insulin action. Reviews in Endocrine & Metabolic Disorders. 5: 143-9. PMID 15041790 DOI: 10.1023/B:Remd.0000021436.91347.93 |
0.484 |
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| 2004 |
Liang CP, Han S, Okamoto H, Carnemolla R, Tabas I, Accili D, Tall AR. Increased CD36 protein as a response to defective insulin signaling in macrophages. The Journal of Clinical Investigation. 113: 764-73. PMID 14991075 DOI: 10.1172/Jci19528 |
0.742 |
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| 2004 |
Kitamura T, Kitamura Y, Nakae J, Giordano A, Cinti S, Kahn CR, Efstratiadis A, Accili D. Mosaic analysis of insulin receptor function. The Journal of Clinical Investigation. 113: 209-19. PMID 14722613 DOI: 10.1172/Jci17810 |
0.558 |
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| 2003 |
Nef S, Verma-Kurvari S, Merenmies J, Vassalli JD, Efstratiadis A, Accili D, Parada LF. Testis determination requires insulin receptor family function in mice. Nature. 426: 291-5. PMID 14628051 DOI: 10.1038/Nature02059 |
0.419 |
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| 2003 |
Hribal ML, Nakae J, Kitamura T, Shutter JR, Accili D. Regulation of insulin-like growth factor-dependent myoblast differentiation by Foxo forkhead transcription factors. The Journal of Cell Biology. 162: 535-41. PMID 12925703 DOI: 10.1083/Jcb.200212107 |
0.431 |
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| 2003 |
Okamoto H, Accili D. In vivo mutagenesis of the insulin receptor. The Journal of Biological Chemistry. 278: 28359-62. PMID 12788928 DOI: 10.1074/Jbc.R300009200 |
0.764 |
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| 2003 |
Altomonte J, Richter A, Harbaran S, Suriawinata J, Nakae J, Thung SN, Meseck M, Accili D, Dong H. Inhibition of Foxo1 function is associated with improved fasting glycemia in diabetic mice. American Journal of Physiology. Endocrinology and Metabolism. 285: E718-28. PMID 12783775 DOI: 10.1152/Ajpendo.00156.2003 |
0.521 |
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| 2003 |
Puigserver P, Rhee J, Donovan J, Walkey CJ, Yoon JC, Oriente F, Kitamura Y, Altomonte J, Dong H, Accili D, Spiegelman BM. Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction. Nature. 423: 550-5. PMID 12754525 DOI: 10.1038/Nature01667 |
0.467 |
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| 2003 |
Nakae J, Kitamura T, Kitamura Y, Biggs WH, Arden KC, Accili D. The forkhead transcription factor Foxo1 regulates adipocyte differentiation. Developmental Cell. 4: 119-29. PMID 12530968 DOI: 10.1016/S1534-5807(02)00401-X |
0.455 |
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| 2003 |
Kim JJ, Accili D. Signalling through IGF-I and insulin receptors: where is the specificity? Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 12: 84-90. PMID 12175645 DOI: 10.1054/Ghir.2002.0265 |
0.497 |
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| 2003 |
Shahn Z, Okamoto H, Accili D, Deckelbaum R, Seo T. 2P-0429 Insulin resistant mice have an atherogenic plasma lipid profile and increased macrophage lipid uptake and deposition Atherosclerosis Supplements. 4: 133. DOI: 10.1016/S1567-5688(03)90571-X |
0.3 |
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| 2002 |
Kitamura T, Nakae J, Kitamura Y, Kido Y, Biggs WH, Wright CV, White MF, Arden KC, Accili D. The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth. The Journal of Clinical Investigation. 110: 1839-47. PMID 12488434 DOI: 10.1172/Jci16857 |
0.493 |
|
| 2002 |
Kitamura T, Kahn CR, Accili D. Insulin receptor knockout mice. Annual Review of Physiology. 65: 313-32. PMID 12471165 DOI: 10.1146/Annurev.Physiol.65.092101.142540 |
0.556 |
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| 2002 |
Xuan S, Kitamura T, Nakae J, Politi K, Kido Y, Fisher PE, Morroni M, Cinti S, White MF, Herrera PL, Accili D, Efstratiadis A. Defective insulin secretion in pancreatic beta cells lacking type 1 IGF receptor. The Journal of Clinical Investigation. 110: 1011-9. PMID 12370279 DOI: 10.1172/Jci15276 |
0.563 |
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| 2002 |
Chin D, Oberfield SE, Silfen ME, McMahon DJ, Manibo AM, Accili D, Levine LS. Proinsulin in girls: relationship to obesity, hyperinsulinemia, and puberty. The Journal of Clinical Endocrinology and Metabolism. 87: 4673-7. PMID 12364457 DOI: 10.1210/Jc.2001-011535 |
0.482 |
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| 2002 |
Nakae J, Biggs WH, Kitamura T, Cavenee WK, Wright CV, Arden KC, Accili D. Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1. Nature Genetics. 32: 245-53. PMID 12219087 DOI: 10.1038/Ng890 |
0.586 |
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| 2002 |
Kido Y, Nakae J, Hribal ML, Xuan S, Efstratiadis A, Accili D. Effects of mutations in the insulin-like growth factor signaling system on embryonic pancreas development and beta-cell compensation to insulin resistance. The Journal of Biological Chemistry. 277: 36740-7. PMID 12101187 DOI: 10.1074/Jbc.M206314200 |
0.565 |
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| 2002 |
Hribal ML, Oriente F, Accili D. Mouse models of insulin resistance. American Journal of Physiology. Endocrinology and Metabolism. 282: E977-81. PMID 11934661 DOI: 10.1152/ajpendo.00561.2001 |
0.502 |
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| 2002 |
Accili D, Kido Y, Nakae J, Lauro D, Park BC. Genetics of type 2 diabetes: insight from targeted mouse mutants. Current Molecular Medicine. 1: 9-23. PMID 11899245 DOI: 10.2174/1566524013364040 |
0.487 |
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| 2002 |
Mauvais-Jarvis F, Ueki K, Fruman DA, Hirshman MF, Sakamoto K, Goodyear LJ, Iannacone M, Accili D, Cantley LC, Kahn CR. Reduced expression of the murine p85alpha subunit of phosphoinositide 3-kinase improves insulin signaling and ameliorates diabetes. The Journal of Clinical Investigation. 109: 141-9. PMID 11781359 DOI: 10.1172/Jci13305 |
0.575 |
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| 2002 |
Nakae J, Kido Y, Accili D. Distinct and overlapping functions of insulin and IGF-I receptors. Endocrine Reviews. 22: 818-35. PMID 11739335 DOI: 10.1210/Edrv.22.6.0452 |
0.488 |
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| 2002 |
Accili D. A kinase in the life of the beta cell. The Journal of Clinical Investigation. 108: 1575-6. PMID 11733550 DOI: 10.1172/Jci14454 |
0.543 |
|
| 2002 |
Kitamura T, Nakae J, Kitamura Y, Kido Y, Biggs WH, Wright CV, White MF, Arden KC, Accili D. The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic β cell growth Journal of Clinical Investigation. 110: 1839-1847. DOI: 10.1172/JCI200216857 |
0.391 |
|
| 2001 |
Nakae J, Kitamura T, Silver DL, Accili D. The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression. The Journal of Clinical Investigation. 108: 1359-67. PMID 11696581 DOI: 10.1172/Jci12876 |
0.56 |
|
| 2001 |
Nakae J, Kitamura T, Ogawa W, Kasuga M, Accili D. Insulin regulation of gene expression through the forkhead transcription factor Foxo1 (Fkhr) requires kinases distinct from Akt. Biochemistry. 40: 11768-76. PMID 11570877 DOI: 10.1021/Bi015532M |
0.458 |
|
| 2001 |
Kitamura T, Kido Y, Nef S, Merenmies J, Parada LF, Accili D. Preserved pancreatic beta-cell development and function in mice lacking the insulin receptor-related receptor. Molecular and Cellular Biology. 21: 5624-30. PMID 11463843 DOI: 10.1128/Mcb.21.16.5624-5630.2001 |
0.549 |
|
| 2001 |
Kim JJ, Park BC, Kido Y, Accili D. Mitogenic and metabolic effects of type I IGF receptor overexpression in insulin receptor-deficient hepatocytes. Endocrinology. 142: 3354-60. PMID 11459778 DOI: 10.1210/Endo.142.8.8332 |
0.498 |
|
| 2001 |
Spravchikov N, Sizyakov G, Gartsbein M, Accili D, Tennenbaum T, Wertheimer E. Glucose effects on skin keratinocytes: implications for diabetes skin complications. Diabetes. 50: 1627-35. PMID 11423485 DOI: 10.2337/Diabetes.50.7.1627 |
0.509 |
|
| 2001 |
Shefi-Friedman L, Wertheimer E, Shen S, Bak A, Accili D, Sampson SR. Increased IGFR activity and glucose transport in cultured skeletal muscle from insulin receptor null mice. American Journal of Physiology. Endocrinology and Metabolism. 281: E16-24. PMID 11404219 DOI: 10.1152/Ajpendo.2001.281.1.E16 |
0.473 |
|
| 2001 |
Nakae J, Kido Y, Accili D. Tissue-specific insulin resistance in type 2 diabetes: lessons from gene-targeted mice. Annals of Medicine. 33: 22-7. PMID 11310935 DOI: 10.3109/07853890109002056 |
0.537 |
|
| 2001 |
Kido Y, Nakae J, Accili D. Clinical review 125: The insulin receptor and its cellular targets. The Journal of Clinical Endocrinology and Metabolism. 86: 972-9. PMID 11238471 DOI: 10.1210/Jcem.86.3.7306 |
0.539 |
|
| 2001 |
Wertheimer E, Spravchikov N, Trebicz M, Gartsbein M, Accili D, Avinoah I, Nofeh-Moses S, Sizyakov G, Tennenbaum T. The regulation of skin proliferation and differentiation in the IR null mouse: implications for skin complications of diabetes. Endocrinology. 142: 1234-41. PMID 11181540 DOI: 10.1210/Endo.142.3.7988 |
0.477 |
|
| 2001 |
Accili D. New perspectives in diabetes research and treatment. Trends in Endocrinology and Metabolism: Tem. 11: 349-50. PMID 11042463 DOI: 10.1016/S1043-2760(00)00326-X |
0.556 |
|
| 2001 |
Nakae J, Kido Y, Kitamura T, Accili D. Glucose homeostasis: lessons from knockout mice Current Opinion in Endocrinology & Diabetes. 8: 82-87. DOI: 10.1097/00060793-200104000-00005 |
0.406 |
|
| 2000 |
Rother KI, Accili D. Role of insulin receptors and IGF receptors in growth and development. Pediatric Nephrology (Berlin, Germany). 14: 558-61. PMID 10912518 DOI: 10.1007/s004670000351 |
0.324 |
|
| 2000 |
Caruso M, Miele C, Oliva A, Condorelli G, Oriente F, Riccardi G, Capaldo B, Fiory F, Accili D, Formisano P, Beguinot F. The IR1152 mutant insulin receptor selectively impairs insulin action in skeletal muscle but not in liver. Diabetes. 49: 1194-202. PMID 10909978 DOI: 10.2337/diabetes.49.7.1194 |
0.447 |
|
| 2000 |
Hribal ML, Federici M, Porzio O, Lauro D, Borboni P, Accili D, Lauro R, Sesti G. The Gly-->Arg972 amino acid polymorphism in insulin receptor substrate-1 affects glucose metabolism in skeletal muscle cells. The Journal of Clinical Endocrinology and Metabolism. 85: 2004-2013. PMID 10843189 DOI: 10.1210/Jcem.85.5.6608 |
0.497 |
|
| 2000 |
Draznin B, Miles P, Kruszynska Y, Olefsky J, Friedman J, Golovchenko I, Stjernholm R, Wall K, Reitman M, Accili D, Cooksey R, McClain D, Goalstone M. Effects of insulin on prenylation as a mechanism of potentially detrimental influence of hyperinsulinemia. Endocrinology. 141: 1310-6. PMID 10746633 DOI: 10.1210/Endo.141.4.7411 |
0.468 |
|
| 2000 |
Tomizawa M, Kumar A, Perrot V, Nakae J, Accili D, Rechler MM, Kumaro A. Insulin inhibits the activation of transcription by a C-terminal fragment of the forkhead transcription factor FKHR. A mechanism for insulin inhibition of insulin-like growth factor-binding protein-1 transcription. The Journal of Biological Chemistry. 275: 7289-95. PMID 10702299 DOI: 10.1074/JBC.275.10.7289 |
0.361 |
|
| 2000 |
Nakae J, Barr V, Accili D. Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR. The Embo Journal. 19: 989-96. PMID 10698940 DOI: 10.1093/Emboj/19.5.989 |
0.455 |
|
| 2000 |
Lauro D, Kido Y, Hayashi H, Ebina Y, Accili D. Expression of kinase-inactive mutant insulin receptors does not rescue insulin receptor-deficient mice from perinatal death. Diabetologia. 42: 1441-2. PMID 10651265 DOI: 10.1007/s001250051318 |
0.4 |
|
| 2000 |
Kido Y, Burks DJ, Withers D, Bruning JC, Kahn CR, White MF, Accili D. Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2 Journal of Clinical Investigation. 105: 199-205. PMID 10642598 DOI: 10.1172/Jci7917 |
0.55 |
|
| 1999 |
Porzio O, Federici M, Hribal ML, Lauro D, Accili D, Lauro R, Borboni P, Sesti G. The Gly972-->Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic beta cells. The Journal of Clinical Investigation. 104: 357-64. PMID 10430617 DOI: 10.1172/Jci5870 |
0.57 |
|
| 1999 |
Park BC, Kido Y, Accili D. Differential signaling of insulin and IGF-1 receptors to glycogen synthesis in murine hepatocytes. Biochemistry. 38: 7517-23. PMID 10360949 DOI: 10.1021/Bi9830718 |
0.52 |
|
| 1999 |
Nakae J, Park BC, Accili D. Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway. The Journal of Biological Chemistry. 274: 15982-5. PMID 10347145 DOI: 10.1074/JBC.274.23.15982 |
0.391 |
|
| 1998 |
Brüning JC, Michael MD, Winnay JN, Hayashi T, Hörsch D, Accili D, Goodyear LJ, Kahn CR. A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance Molecular Cell. 2: 559-569. PMID 9844629 DOI: 10.1016/S1097-2765(00)80155-0 |
0.438 |
|
| 1998 |
Lauro D, Kido Y, Castle AL, Zarnowski MJ, Hayashi H, Ebina Y, Accili D. Impaired glucose tolerance in mice with a targeted impairment of insulin action in muscle and adipose tissue. Nature Genetics. 20: 294-8. PMID 9806552 DOI: 10.1038/3112 |
0.486 |
|
| 1998 |
Goalstone ML, Leitner JW, Wall K, Dolgonos L, Rother KI, Accili D, Draznin B. Effect of insulin on farnesyltransferase. Specificity of insulin action and potentiation of nuclear effects of insulin-like growth factor-1, epidermal growth factor, and platelet-derived growth factor. The Journal of Biological Chemistry. 273: 23892-6. PMID 9727002 DOI: 10.1074/JBC.273.37.23892 |
0.436 |
|
| 1998 |
Yu S, Yu D, Lee E, Eckhaus M, Lee R, Corria Z, Accili D, Westphal H, Weinstein LS. Variable and tissue-specific hormone resistance in heterotrimeric Gs protein alpha-subunit (Gsalpha) knockout mice is due to tissue-specific imprinting of the gsalpha gene. Proceedings of the National Academy of Sciences of the United States of America. 95: 8715-20. PMID 9671744 DOI: 10.1073/Pnas.95.15.8715 |
0.31 |
|
| 1998 |
Rother KI, Imai Y, Caruso M, Beguinot F, Formisano P, Accili D. Evidence that IRS-2 phosphorylation is required for insulin action in hepatocytes. The Journal of Biological Chemistry. 273: 17491-7. PMID 9651339 DOI: 10.1074/JBC.273.28.17491 |
0.424 |
|
| 1998 |
Salvatore P, Hanash CR, Kido Y, Imai Y, Accili D. Identification of sirm, a novel insulin-regulated SH3 binding protein that associates with Grb-2 and FYN. The Journal of Biological Chemistry. 273: 6989-97. PMID 9507006 DOI: 10.1074/jbc.273.12.6989 |
0.466 |
|
| 1998 |
Cinti S, Eberbach S, Castellucci M, Accili D. Lack of insulin receptors affects the formation of white adipose tissue in mice. A morphometric and ultrastructural analysis. Diabetologia. 41: 171-7. PMID 9498650 DOI: 10.1007/s001250050886 |
0.43 |
|
| 1997 |
Brüning JC, Winnay J, Bonner-Weir S, Taylor SI, Accili D, Kahn CR. Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles Cell. 88: 561-572. PMID 9038347 DOI: 10.1016/S0092-8674(00)81896-6 |
0.503 |
|
| 1996 |
Jui HY, Accili D, Taylor SI. Characterization of a hybrid receptor formed by dimerization of the insulin receptor-related receptor (IRR) with the insulin receptor (IR): Coexpression of cDNAs encoding human IRR and human IR in NIH-3T3 cells Biochemistry. 35: 14326-14330. PMID 8916919 DOI: 10.1021/Bi9613032 |
0.484 |
|
| 1996 |
Accili D, Drago J, Lee EJ, Johnson MD, Cool MH, Salvatore P, Asico LD, Jose PA, Taylor SI, Westphal H. Early neonatal death in mice homozygous for a null allele of the insulin receptor gene Nature Genetics. 12: 106-109. PMID 8528241 DOI: 10.1038/Ng0196-106 |
0.477 |
|
| 1995 |
Voliovitch H, Schindler DG, Hadari YR, Taylor SI, Accili D, Zick Y. Tyrosine phosphorylation of insulin receptor substrate-1 in vivo depends upon the presence of its pleckstrin homology region. The Journal of Biological Chemistry. 270: 18083-7. PMID 7629118 DOI: 10.1074/Jbc.270.30.18083 |
0.314 |
|
| 1995 |
Najjar SM, Philippe N, Suzuki Y, Ignacio GA, Formisano P, Accili D, Taylor SI. Insulin-stimulated phosphorylation of recombinant pp120/HA4, an endogenous substrate of the insulin receptor tyrosine kinase. Biochemistry. 34: 9341-9. PMID 7626603 DOI: 10.1021/Bi00029A009 |
0.437 |
|
| 1995 |
Formisano P, Najjar SM, Gross CN, Philippe N, Oriente F, Kern-Buell CL, Accili D, Gorden P. Receptor-mediated internalization of insulin. Potential role of pp120/HA4, a substrate of the insulin receptor kinase. The Journal of Biological Chemistry. 270: 24073-7. PMID 7592607 DOI: 10.1074/jbc.270.41.24073 |
0.423 |
|
| 1994 |
Taylor SI, Accili D, Haft CR, Hone J, Imai Y, Levy-Toledano R, Quon MJ, Suzuki Y, Wertheimer E. Mechanisms of hormone resistance: lessons from insulin-resistant patients Acta Paediatrica (Oslo, Norway : 1992). Supplement. 399: 95-104. PMID 7949626 DOI: 10.1111/J.1651-2227.1994.Tb13300.X |
0.372 |
|
| 1994 |
Taylor SI, Accili D. The structure and function of insulin receptors Current Opinion in Endocrinology and Diabetes. 1: 231-238. DOI: 10.1097/00060793-199400010-00042 |
0.463 |
|
| 1993 |
Levy-Toledano R, Accili D, Taylor SI. Deletion of C-terminal 113 amino acids impairs processing and internalization of human insulin receptor: Comparison of receptors expressed in CHO and NIH-3T3 cells Bba - Molecular Cell Research. 1220: 1-14. PMID 8268238 DOI: 10.1016/0167-4889(93)90090-C |
0.418 |
|
| 1993 |
Najjar SM, Philippe N, Taylor SI, Accili D. Molecular cloning of pp120/ ecto-ATPase, an endogenous substrate of the insulin receptor kinase Advances in Experimental Medicine and Biology. 343: 169-174. PMID 8184737 DOI: 10.1007/978-1-4615-2988-0_17 |
0.378 |
|
| 1992 |
Taylor SI, Cama A, Accili D, Barbetti F, Quon MJ, De La Luz Sierra M, Suzuki Y, Koller E, Levy-Toledano R, Wertheimer E, Moncada VY, Kadowaki H, Kadowaki T. Mutations in the insulin receptor gene Endocrine Reviews. 13: 566-595. PMID 1330507 DOI: 10.1210/Edrv-13-3-566 |
0.409 |
|
| 1991 |
Taylor SI, Accili D, Cama A, Imano E, Kadowaki H, Kadowaki T. Unusual forms of insulin resistance Annual Review of Medicine. 42: 373-379. PMID 2035982 DOI: 10.1146/Annurev.Me.42.020191.002105 |
0.538 |
|
| 1991 |
Taylor SI, Cama A, Accili D, Barbetti F, Imano E, Kadowaki H, Kadowaki T. Genetic basis of endocrine disease 1: Molecular genetics of insulin resistant diabetes mellitus Journal of Clinical Endocrinology and Metabolism. 73: 1158-1163. PMID 1955495 DOI: 10.1210/Jcem-73-6-1158 |
0.55 |
|
| 1990 |
Barbetti F, Raben N, Kadowaki T, Cama A, Accili D, Gabbay KH, Merenich JA, Taylor SI, Roth J. Two unrelated patients with familial hyperproinsulinemia due to a mutation substituting histidine for arginine at position 65 in the proinsulin molecule: Identification of the mutation by direct sequencing of genomic deoxyribonucleic acid amplified by polymerase chain reaction Journal of Clinical Endocrinology and Metabolism. 71: 164-169. PMID 2196279 DOI: 10.1210/Jcem-71-1-164 |
0.424 |
|
| 1990 |
Taylor SI, Cama A, Kadowaki H, Kadowaki T, Accili D. Mutations of the human insulin receptor gene Trends in Endocrinology and Metabolism. 1: 134-139. DOI: 10.1016/1043-2760(90)90024-W |
0.389 |
|
| 1989 |
Odawara M, Kadowaki T, Yamamoto R, Shibasaki Y, Tobe K, Accili D, Bevins C, Mikami Y, Matsuura N, Akanuma Y, Takaku F, Taylor SI, Kasuga M. Human diabetes associated with a mutation in the tyrosine kinase domain of the insulin receptor Science. 245: 66-68. PMID 2544998 DOI: 10.1126/science.2544998 |
0.307 |
|
| 1989 |
Taylor SI, Barbetti F, Accili D, Roth J, Gorden P. Syndromes of Autoimmunity and Hypoglycemia: Autoantibodies Directed Against insulinand Its Receptor Endocrinology and Metabolism Clinics of North America. 18: 123-143. DOI: 10.1016/S0889-8529(18)30392-X |
0.515 |
|
| 1987 |
Perrotti N, Accili D, Marcus-Samuels B, Rees-Jones RW, Taylor SI. Insulin stimulates phosphorylation of a 120-kDa glycoprotein substrate (pp120) for the receptor-associated protein kinase in intact H-35 hepatoma cells. Proceedings of the National Academy of Sciences of the United States of America. 84: 3137-40. PMID 3033636 DOI: 10.1073/Pnas.84.10.3137 |
0.433 |
|
| 1986 |
Accili D, Perrotti N, Rees-Jones R, Taylor SI. Tissue distribution and subcellular localization of an endogenous substrate (pp 120) for the insulin receptor-associated tyrosine kinase. Endocrinology. 119: 1274-80. PMID 3015574 DOI: 10.1210/Endo-119-3-1274 |
0.374 |
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