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Karl J. Clark, Ph.D. - Publications

Affiliations: 
1990-1994 Biology/Chemistry University of Wisconsin-Eau Claire, Eau Claire, WI, United States 
 1995-2003 Molecular, Cellular, Developmental Biology and Genetics University of Minnesota, Twin Cities, Minneapolis, MN 
 2004-2007 Animal Science University of Minnesota, Twin Cities, Minneapolis, MN 
 2008- Biochemistry and Molecular Biology Mayo Clinic, Rochester, MN, United States 
Area:
Genetics, Molecular Biology, Behavior, Gene Editing
Website:
https://www.mayo.edu/research/faculty/clark-karl-j-ph-d/bio-00096400
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89 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Lee H, Shams S, Thi VHD, Boyum G, Modhurima R, Hall E, Green I, Cervantes E, Miguez F, Clark K. The canonical HPA axis facilitates and maintains light adaptive behavior. Research Square. PMID 37720015 DOI: 10.21203/rs.3.rs-3240080/v1  0.637
2023 Kar B, Castillo SR, Sabharwal A, Clark KJ, Ekker SC. Mitochondrial Base Editing: Recent Advances towards Therapeutic Opportunities. International Journal of Molecular Sciences. 24. PMID 36982871 DOI: 10.3390/ijms24065798  0.518
2022 Sabharwal A, Wishman MD, Cervera RL, Serres MR, Anderson JL, Holmberg SR, Kar B, Treichel AJ, Ichino N, Liu W, Yang J, Ding Y, Deng Y, Lacey JM, Laxen WJ, ... ... Clark KJ, et al. Genetic therapy in a mitochondrial disease model suggests a critical role for liver dysfunction in mortality. Elife. 11. PMID 36408801 DOI: 10.7554/eLife.65488  0.516
2022 Ding Y, Lang D, Yan J, Bu H, Li H, Jiao K, Yang J, Ni H, Morotti S, Le T, Clark KJ, Port J, Ekker SC, Cao H, Zhang Y, et al. A phenotype-based forward genetic screen identifies as a sick sinus syndrome gene. Elife. 11. PMID 36255053 DOI: 10.7554/eLife.77327  0.563
2022 Sabharwal A, Campbell JM, Schwab TL, WareJoncas Z, Wishman MD, Ata H, Liu W, Ichino N, Hunter DE, Bergren JD, Urban MD, Urban RM, Holmberg SR, Kar B, Cook A, ... ... Clark KJ, et al. A Primer Genetic Toolkit for Exploring Mitochondrial Biology and Disease Using Zebrafish. Genes. 13. PMID 35893052 DOI: 10.3390/genes13081317  0.534
2022 Liu F, Kambakam S, Almeida MP, Ming Z, Welker JM, Wierson WA, Schultz-Rogers LE, Ekker SC, Clark KJ, Essner JJ, McGrail M. Cre/ regulated conditional rescue and inactivation with zebrafish UFlip alleles generated by CRISPR-Cas9 targeted integration. Elife. 11. PMID 35713402 DOI: 10.7554/eLife.71478  0.589
2022 Kar B, Sabharwal A, Restrepo-Castillo S, Simone BW, Clark KJ, Ekker SC. An optimized FusX assembly-based technique to introduce mitochondrial TC-to-TT variations in human cell lines. Star Protocols. 3: 101288. PMID 35496789 DOI: 10.1016/j.xpro.2022.101288  0.479
2021 Simone BW, Lee HB, Daby CL, Ata H, Restrepo-Castillo S, Martínez-Gálvez G, Kar B, Gendron WAC, Clark KJ, Ekker SC. Chimeric RNA:DNA TracrRNA Improves Homology-Directed Repair and . The Crispr Journal. PMID 34935462 DOI: 10.1089/crispr.2021.0087  0.699
2021 Sabharwal A, Kar B, Restrepo-Castillo S, Holmberg SR, Mathew ND, Kendall BL, Cotter RP, WareJoncas Z, Seiler C, Nakamaru-Ogiso E, Clark KJ, Ekker SC. The FusX TALE Base Editor (FusXTBE) for Rapid Mitochondrial DNA Programming of Human Cells and Zebrafish Disease Models . The Crispr Journal. 4: 799-821. PMID 34847747 DOI: 10.1089/crispr.2021.0061  0.549
2021 Welker JM, Wierson WA, Almeida MP, Mann CM, Torrie ME, Ming Z, Ekker SC, Clark KJ, Dobbs DL, Essner JJ, McGrail M. GeneWeld: Efficient Targeted Integration Directed by Short Homology in Zebrafish. Bio-Protocol. 11: e4100. PMID 34395736 DOI: 10.21769/BioProtoc.4100  0.558
2021 Saha K, Sontheimer EJ, Brooks PJ, Dwinell MR, Gersbach CA, Liu DR, Murray SA, Tsai SQ, Wilson RC, Anderson DG, Asokan A, Banfield JF, Bankiewicz KS, Bao G, Bulte JWM, ... ... Clark KJ, et al. The NIH Somatic Cell Genome Editing program. Nature. 592: 195-204. PMID 33828315 DOI: 10.1038/s41586-021-03191-1  0.54
2021 Almeida MP, Welker JM, Siddiqui S, Luiken J, Ekker SC, Clark KJ, Essner JJ, McGrail M. Endogenous zebrafish proneural Cre drivers generated by CRISPR/Cas9 short homology directed targeted integration. Scientific Reports. 11: 1732. PMID 33462297 DOI: 10.1038/s41598-021-81239-y  0.548
2020 Ichino N, Serres MR, Urban RM, Urban MD, Treichel AJ, Schaefbauer KJ, Greif LE, Varshney GK, Skuster KJ, McNulty MS, Daby CL, Wang Y, Liao HK, El-Rass S, Ding Y, ... ... Clark KJ, et al. Building the vertebrate codex using the gene breaking protein trap library. Elife. 9. PMID 32779569 DOI: 10.7554/Elife.54572  0.624
2020 Pinto E Vairo F, Kroc SA, Bertsch NL, Sigafoos AN, Lee HB, Dsouza NR, Clark KJ, Pichurin PN, Zimmermann MT, Klee EW. Biallelic variants in PROZ as a cause of hypercoagulability and livedo racemosa. Thrombosis Research. 195: 187-189. PMID 32721632 DOI: 10.1016/J.Thromres.2020.07.014  0.534
2020 Wierson WA, Welker JM, Almeida MP, Mann CM, Webster DA, Torrie ME, Weiss TJ, Kambakam S, Vollbrecht MK, Lan M, McKeighan KC, Levey J, Ming Z, Wehmeier A, Mikelson CS, ... ... Clark KJ, et al. Efficient targeted integration directed by short homology in zebrafish and mammalian cells. Elife. 9. PMID 32412410 DOI: 10.7554/Elife.53968  0.618
2020 Ichino N, Serres MR, Urban RM, Urban MD, Treichel AJ, Schaefbauer KJ, Greif LE, Varshney GK, Skuster KJ, McNulty MS, Daby CL, Wang Y, Liao H, El-Rass S, Ding Y, ... ... Clark KJ, et al. Author response: Building the vertebrate codex using the gene breaking protein trap library Elife. DOI: 10.7554/Elife.54572.Sa2  0.558
2020 Wierson WA, Welker JM, Almeida MP, Mann CM, Webster DA, Torrie ME, Weiss TJ, Kambakam S, Vollbrecht MK, Lan M, McKeighan KC, Levey J, Ming Z, Wehmeier A, Mikelson CS, ... ... Clark KJ, et al. Author response: Efficient targeted integration directed by short homology in zebrafish and mammalian cells Elife. DOI: 10.7554/Elife.53968.Sa2  0.557
2020 Mehra D, Banerjee C, Adhikari S, Clark KJ, Ekker SC, Puchner EM. Characterization of dCas9 Interaction Kinetics and Local Chromatin Structure in Live Human Cells using Palm Superresolution Microscopy Biophysical Journal. 118: 146a. DOI: 10.1016/J.Bpj.2019.11.919  0.507
2019 Wierson WA, Simone BW, WareJoncas Z, Mann C, Welker JM, Kar B, Emch MJ, Friedberg I, Gendron WAC, Barry MA, Clark KJ, Dobbs DL, McGrail MA, Ekker SC, Essner JJ. Expanding the CRISPR Toolbox with ErCas12a in Zebrafish and Human Cells. The Crispr Journal. PMID 31742435 DOI: 10.1089/crispr.2019.0026  0.549
2019 Zawerton A, Mignot C, Sigafoos A, Blackburn PR, Haseeb A, McWalter K, Ichikawa S, Nava C, Keren B, Charles P, Marey I, Tabet AC, Levy J, Perrin L, Hartmann A, ... ... Clark KJ, et al. Widening of the genetic and clinical spectrum of Lamb-Shaffer syndrome, a neurodevelopmental disorder due to SOX5 haploinsufficiency. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 31578471 DOI: 10.1038/S41436-019-0657-0  0.316
2019 Gupta A, Zimmermann MT, Wang H, Broski SM, Sigafoos AN, Macklin SK, Urrutia RA, Clark KJ, Atwal PS, Pignolo RJ, Klee EW. Molecular characterization of known and novel ACVR1 variants in phenotypes of aberrant ossification. American Journal of Medical Genetics. Part A. PMID 31240838 DOI: 10.1002/Ajmg.A.61274  0.342
2019 Mann CM, Martínez-Gálvez G, Welker JM, Wierson WA, Ata H, Almeida MP, Clark KJ, Essner JJ, McGrail M, Ekker SC, Dobbs D. The Gene Sculpt Suite: a set of tools for genome editing. Nucleic Acids Research. PMID 31127311 DOI: 10.1093/Nar/Gkz405  0.591
2019 Nelson CM, Lennon VA, Lee H, Krug RG, Kamalova A, Madigan NN, Clark KJ, Windebank AJ, Henley JR. Glucocorticoids Target Ependymal Glia and Inhibit Repair of the Injured Spinal Cord. Frontiers in Cell and Developmental Biology. 7: 56. PMID 31069223 DOI: 10.3389/Fcell.2019.00056  0.747
2018 Lee HB, Schwab TL, Sigafoos AN, Gauerke JL, Krug RG, Serres MR, Jacobs DC, Cotter RP, Das B, Petersen MO, Daby CL, Urban RM, Berry BC, Clark KJ. Novel Zebrafish Behavioral Assay to Identify Modifiers of the Rapid, Nongenomic Stress Response. Genes, Brain, and Behavior. e12549. PMID 30588759 DOI: 10.1111/Gbb.12549  0.774
2018 Ata H, Ekstrom TL, Martínez-Gálvez G, Mann CM, Dvornikov AV, Schaefbauer KJ, Ma AC, Dobbs D, Clark KJ, Ekker SC. Robust Activation of Microhomology-mediated End Joining for Precision Gene Editing Applications. Plos Genetics. 14: e1007652. PMID 30208061 DOI: 10.1371/Journal.Pgen.1007652  0.637
2018 Kim J, Clark K, Barton C, Tanguay R, Moulton H. A Novel Zebrafish Model for Assessing In Vivo Delivery of Morpholino Oligomers. Methods in Molecular Biology (Clifton, N.J.). 1828: 293-306. PMID 30171549 DOI: 10.1007/978-1-4939-8651-4_18  0.357
2018 Becker NA, Schwab TL, Clark KJ, Maher LJ. Bacterial gene control by DNA looping using engineered dimeric transcription activator like effector (TALE) proteins. Nucleic Acids Research. PMID 29390154 DOI: 10.1093/Nar/Gky047  0.34
2018 Krug RG, Lee HB, El Khoury LY, Sigafoos AN, Petersen MO, Clark KJ. The endocannabinoid gene faah2a modulates stress-associated behavior in zebrafish. Plos One. 13: e0190897. PMID 29304078 DOI: 10.1371/Journal.Pone.0190897  0.772
2017 El-Rass S, Eisa-Beygi S, Khong E, Brand-Arzamendi K, Mauro A, Zhang H, Clark KJ, Ekker SC, Wen XY. Disruption of pdgfra alters endocardial and myocardial fusion during zebrafish cardiac assembly. Biology Open. PMID 28167492 DOI: 10.1242/Bio.021212  0.556
2017 Becker NA, Schwab TL, Clark KJ, Maher LJ. Engineering DNA Looping in E. Coli Biophysical Journal. 112: 68a. DOI: 10.1016/J.Bpj.2016.11.411  0.323
2016 Gerlai R, Poshusta TL, Rampersad M, Fernandes Y, Greenwood TM, Cousin MA, Klee EW, Clark KJ. Forward Genetic Screening Using Behavioral Tests in Zebrafish: A Proof of Concept Analysis of Mutants. Behavior Genetics. PMID 27704300 DOI: 10.1007/S10519-016-9818-Y  0.571
2016 Ata H, Clark KJ, Ekker SC. The zebrafish genome editing toolkit. Methods in Cell Biology. 135: 149-70. PMID 27443924 DOI: 10.1016/Bs.Mcb.2016.04.023  0.603
2016 Blackburn PR, Hickey RD, Nace RA, Giama NH, Kraft DL, Bordner AJ, Chaiteerakij R, McCormick JB, Radulovic M, Graham RP, Torbenson MS, Tortorelli S, Scott CR, Lindor NM, Milliner DS, ... ... Clark KJ, et al. Silent Tyrosinemia Type I Without Elevated Tyrosine or Succinylacetone Associated With Liver Cirrhosis and Hepatocellular Carcinoma. Human Mutation. PMID 27397503 DOI: 10.1002/Humu.23047  0.525
2016 Wang Y, Ding X, Wang S, Moser CD, Shaleh HM, Mohamed EA, Chaiteerakij R, Allotey LK, Chen G, Miyabe K, McNulty MS, Ndzengue A, Knudson RA, Greipp PT, Clark KJ, et al. Antitumor effect of FGFR inhibitors on a novel cholangiocarcinoma patient derived xenograft mouse model endogenously expressing an FGFR2-CCDC6 fusion protein. Cancer Letters. PMID 27216979 DOI: 10.1016/J.Canlet.2016.05.017  0.303
2016 Welker JM, Wierson WA, Wang Y, McNulty MS, Tanya PL, Tisdale EE, Solin SL, Ekker SC, Clark KJ, McGrail MA, Essner JJ. GoldyTALEN Vectors with Improved Efficiency for Golden Gate TALEN Assembly. Human Gene Therapy. PMID 27094430 DOI: 10.1089/Hum.2016.012  0.567
2016 Lee HB, Sundberg BN, Sigafoos AN, Clark KJ. Genome Engineering with TALE and CRISPR Systems in Neuroscience. Frontiers in Genetics. 7: 47. PMID 27092173 DOI: 10.3389/Fgene.2016.00047  0.625
2016 Leveque RE, Clark KJ, Ekker SC. Mayo Clinic Zebrafish Facility Overview. Zebrafish. PMID 27023741 DOI: 10.1089/Zeb.2015.1227  0.575
2016 Lee HB, Schwab TL, Koleilat A, Ata H, Daby CL, Lopez Cervera R, McNulty MS, Bostwick HS, Clark KJ. Allele-Specific Quantitative PCR for Accurate, Rapid, and Cost-Effective Genotyping. Human Gene Therapy. PMID 26986823 DOI: 10.1089/Hum.2016.011  0.541
2016 Ma AC, McNulty MS, Tanya PL, Jarryd CM, Martínez-Gálvez G, Argue DP, Lee HB, Urban MD, Bullard CE, Blackburn PR, Man TK, Clark KJ, Ekker SC. FusX: A rapid one-step TALE assembly system for genome science. Human Gene Therapy. PMID 26854857 DOI: 10.1089/Hum.2015.172  0.705
2015 Krug RG, Clark KJ. Elucidating cannabinoid biology in zebrafish (Danio rerio). Gene. 570: 168-79. PMID 26192460 DOI: 10.1016/J.Gene.2015.07.036  0.798
2015 Westcot SE, Hatzold J, Urban MD, Richetti SK, Skuster KJ, Harm RM, Lopez Cervera R, Umemoto N, McNulty MS, Clark KJ, Hammerschmidt M, Ekker SC. Protein-Trap Insertional Mutagenesis Uncovers New Genes Involved in Zebrafish Skin Development, Including a Neuregulin 2a-Based ErbB Signaling Pathway Required during Median Fin Fold Morphogenesis. Plos One. 10: e0130688. PMID 26110643 DOI: 10.1371/Journal.Pone.0130688  0.59
2015 Blackburn P, Hickey R, Nace R, Giama NH, Chaiteerakij R, Bordner A, Kraft D, Oglesbee D, Al-Qabandi W, Grompe M, Clark KJ, Klee EW, Gavrilov D, Roberts LR, El-Youssef M, et al. 549 Tyrosinemia Without Succinylacetone: Modeling a Novel Mutation in FAH in Family With Early Onset Cirrhosis and Hepatocellular Carcinoma Gastroenterology. 148: S-111. DOI: 10.1016/S0016-5085(15)30381-4  0.5
2014 Peng Y, Clark KJ, Campbell JM, Panetta MR, Guo Y, Ekker SC. Making designer mutants in model organisms. Development (Cambridge, England). 141: 4042-54. PMID 25336735 DOI: 10.1242/Dev.102186  0.589
2014 Krug RG, Poshusta TL, Skuster KJ, Berg MR, Gardner SL, Clark KJ. A transgenic zebrafish model for monitoring glucocorticoid receptor activity. Genes, Brain, and Behavior. PMID 24679220 DOI: 10.1111/Gbb.12135  0.782
2013 Ma AC, Lee HB, Clark KJ, Ekker SC. High efficiency In Vivo genome engineering with a simplified 15-RVD GoldyTALEN design. Plos One. 8: e65259. PMID 23734242 DOI: 10.1371/Journal.Pone.0065259  0.701
2013 Patowary A, Purkanti R, Singh M, Chauhan R, Singh AR, Swarnkar M, Singh N, Pandey V, Torroja C, Clark MD, Kocher JP, Clark KJ, Stemple DL, Klee EW, Ekker SC, et al. A sequence-based variation map of zebrafish. Zebrafish. 10: 15-20. PMID 23590399 DOI: 10.1089/Zeb.2012.0848  0.596
2013 Blackburn PR, Campbell JM, Clark KJ, Ekker SC. The CRISPR system--keeping zebrafish gene targeting fresh. Zebrafish. 10: 116-8. PMID 23536990 DOI: 10.1089/Zeb.2013.9999  0.602
2013 Neff KL, Argue DP, Ma AC, Lee HB, Clark KJ, Ekker SC. Mojo Hand, a TALEN design tool for genome editing applications. Bmc Bioinformatics. 14: 1. PMID 23323762 DOI: 10.1186/1471-2105-14-1  0.686
2013 Ding Y, Liu W, Deng Y, Jomok B, Yang J, Huang W, Clark KJ, Zhong TP, Lin X, Ekker SC, Xu X. Trapping cardiac recessive mutants via expression-based insertional mutagenesis screening. Circulation Research. 112: 606-17. PMID 23283723 DOI: 10.1161/Circresaha.112.300603  0.581
2012 Hoffman SJ, Psaltis PJ, Clark KJ, Spoon DB, Chue CD, Ekker SC, Simari RD. An in vivo method to quantify lymphangiogenesis in zebrafish. Plos One. 7: e45240. PMID 23028871 DOI: 10.1371/Journal.Pone.0045240  0.558
2012 Bedell VM, Wang Y, Campbell JM, Poshusta TL, Starker CG, Krug RG, Tan W, Penheiter SG, Ma AC, Leung AY, Fahrenkrug SC, Carlson DF, Voytas DF, Clark KJ, Essner JJ, et al. In vivo genome editing using a high-efficiency TALEN system. Nature. 491: 114-8. PMID 23000899 DOI: 10.1038/Nature11537  0.793
2012 Hoeppner LH, Phoenix KN, Clark KJ, Bhattacharya R, Gong X, Sciuto TE, Vohra P, Suresh S, Bhattacharya S, Dvorak AM, Ekker SC, Dvorak HF, Claffey KP, Mukhopadhyay D. Revealing the role of phospholipase Cβ3 in the regulation of VEGF-induced vascular permeability. Blood. 120: 2167-73. PMID 22674805 DOI: 10.1182/Blood-2012-03-417824  0.557
2012 Xu J, Gao J, Li J, Xue L, Clark KJ, Ekker SC, Du SJ. Functional analysis of slow myosin heavy chain 1 and myomesin-3 in sarcomere organization in zebrafish embryonic slow muscles. Journal of Genetics and Genomics = Yi Chuan Xue Bao. 39: 69-80. PMID 22361506 DOI: 10.1016/J.Jgg.2012.01.005  0.539
2012 Liao HK, Wang Y, Noack Watt KE, Wen Q, Breitbach J, Kemmet CK, Clark KJ, Ekker SC, Essner JJ, McGrail M. Tol2 gene trap integrations in the zebrafish amyloid precursor protein genes appa and aplp2 reveal accumulation of secreted APP at the embryonic veins. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 241: 415-25. PMID 22275008 DOI: 10.1002/Dvdy.23725  0.565
2012 Bedell VM, Person AD, Larson JD, McLoon A, Balciunas D, Clark KJ, Neff KI, Nelson KE, Bill BR, Schimmenti LA, Beiraghi S, Ekker SC. The lineage-specific gene ponzr1 is essential for zebrafish pronephric and pharyngeal arch development. Development (Cambridge, England). 139: 793-804. PMID 22274699 DOI: 10.1242/Dev.071720  0.796
2012 Klee EW, Schneider H, Clark KJ, Cousin MA, Ebbert JO, Hooten WM, Karpyak VM, Warner DO, Ekker SC. Zebrafish: a model for the study of addiction genetics. Human Genetics. 131: 977-1008. PMID 22207143 DOI: 10.1007/S00439-011-1128-0  0.578
2012 Clark KJ, Argue DP, Petzold AM, Ekker SC. zfishbook: connecting you to a world of zebrafish revertible mutants. Nucleic Acids Research. 40: D907-11. PMID 22067444 DOI: 10.1093/Nar/Gkr957  0.788
2011 Clark KJ, Voytas DF, Ekker SC. A TALE of two nucleases: gene targeting for the masses? Zebrafish. 8: 147-9. PMID 21929364 DOI: 10.1089/Zeb.2011.9993  0.612
2011 Clark KJ, Urban MD, Skuster KJ, Ekker SC. Transgenic zebrafish using transposable elements. Methods in Cell Biology. 104: 137-49. PMID 21924161 DOI: 10.1016/B978-0-12-374814-0.00008-2  0.593
2011 Hyland KA, Olson ER, Clark KJ, Aronovich EL, Hackett PB, Blazar BR, Tolar J, Scott McIvor R. Sleeping Beauty-mediated correction of Fanconi anemia type C. The Journal of Gene Medicine. 13: 462-9. PMID 21766398 DOI: 10.1002/Jgm.1589  0.559
2011 Clark KJ, Boczek NJ, Ekker SC. Stressing zebrafish for behavioral genetics. Reviews in the Neurosciences. 22: 49-62. PMID 21615261 DOI: 10.1515/Rns.2011.007  0.565
2011 Clark KJ, Balciunas D, Pogoda HM, Ding Y, Westcot SE, Bedell VM, Greenwood TM, Urban MD, Skuster KJ, Petzold AM, Ni J, Nielsen AL, Patowary A, Scaria V, Sivasubbu S, et al. In vivo protein trapping produces a functional expression codex of the vertebrate proteome. Nature Methods. 8: 506-15. PMID 21552255 DOI: 10.1038/Nmeth.1606  0.799
2011 Carlson DF, Garbe JR, Tan W, Martin MJ, Dobrinsky JR, Hackett PB, Clark KJ, Fahrenkrug SC. Strategies for selection marker-free swine transgenesis using the Sleeping Beauty transposon system. Transgenic Research. 20: 1125-37. PMID 21221779 DOI: 10.1007/S11248-010-9481-7  0.744
2011 Westcot SE, Clark KJ, Skuster K, Urban M, Moulder G, Greenwood TM, Balciunas D, Sivasubbu S, Ekker SC. How to skin a fish: The Zebrafish Integument Project and novel epidermal mutant wicked witch of the Midwest Developmental Biology. 356: 158. DOI: 10.1016/J.Ydbio.2011.05.586  0.535
2011 Bedell VM, Person A, Larson J, McLoon A, Balciunas D, Clark K, Nelson K, Bill B, Schimmenti L, Beiraghi S, Ekker S. Vertebrate kidney innovation by ponzr1 Developmental Biology. 356: 255. DOI: 10.1016/J.Ydbio.2011.05.579  0.744
2010 Garbe JR, Elsik CG, Antoniou E, Reecy JM, Clark KJ, Venkatraman A, Kim JW, Schnabel RD, Michael Dickens C, Wolfinger RD, Fahrenkrug SC, Taylor JF. Development and application of bovine and porcine oligonucleotide arrays with protein-based annotation. Journal of Biomedicine & Biotechnology. 2010: 453638. PMID 21197395 DOI: 10.1155/2010/453638  0.66
2010 Wang Y, Kaiser MS, Larson JD, Nasevicius A, Clark KJ, Wadman SA, Roberg-Perez SE, Ekker SC, Hackett PB, McGrail M, Essner JJ. Moesin1 and Ve-cadherin are required in endothelial cells during in vivo tubulogenesis. Development (Cambridge, England). 137: 3119-28. PMID 20736288 DOI: 10.1242/Dev.048785  0.764
2010 Petzold AM, Bedell VM, Boczek NJ, Essner JJ, Balciunas D, Clark KJ, Ekker SC. SCORE imaging: specimen in a corrected optical rotational enclosure. Zebrafish. 7: 149-54. PMID 20528262 DOI: 10.1089/Zeb.2010.0660  0.759
2009 Petzold AM, Balciunas D, Sivasubbu S, Clark KJ, Bedell VM, Westcot SE, Myers SR, Moulder GL, Thomas MJ, Ekker SC. Nicotine response genetics in the zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 106: 18662-7. PMID 19858493 DOI: 10.1073/Pnas.0908247106  0.784
2009 Petzold AM, Clark KJ, Ekker SC. Spotlight on the future of scientific publication. Zebrafish. 6: 215-7. PMID 19761376 DOI: 10.1089/Zeb.2009.9992  0.738
2009 Kalén M, Wallgard E, Asker N, Nasevicius A, Athley E, Billgren E, Larson JD, Wadman SA, Norseng E, Clark KJ, He L, Karlsson-Lindahl L, Häger AK, Weber H, Augustin H, et al. Combination of reverse and chemical genetic screens reveals angiogenesis inhibitors and targets. Chemistry & Biology. 16: 432-41. PMID 19389629 DOI: 10.1016/J.Chembiol.2009.02.010  0.779
2009 Bill BR, Petzold AM, Clark KJ, Schimmenti LA, Ekker SC. A primer for morpholino use in zebrafish. Zebrafish. 6: 69-77. PMID 19374550 DOI: 10.1089/Zeb.2008.0555  0.76
2009 Clark KJ, Carlson DF, Leaver MJ, Foster LK, Fahrenkrug SC. Passport, a native Tc1 transposon from flatfish, is functionally active in vertebrate cells. Nucleic Acids Research. 37: 1239-47. PMID 19136468 DOI: 10.1093/Nar/Gkn1025  0.659
2008 Ni J, Clark KJ, Fahrenkrug SC, Ekker SC. Transposon tools hopping in vertebrates. Briefings in Functional Genomics & Proteomics. 7: 444-53. PMID 19109308 DOI: 10.1093/Bfgp/Eln049  0.74
2007 Clark KJ, Carlson DF, Fahrenkrug SC. Pigs taking wing with transposons and recombinases. Genome Biology. 8: S13. PMID 18047690 DOI: 10.1186/Gb-2007-8-S1-S13  0.651
2007 Clark KJ, Carlson DF, Foster LK, Kong BW, Foster DN, Fahrenkrug SC. Enzymatic engineering of the porcine genome with transposons and recombinases Bmc Biotechnology. 7. PMID 17640337 DOI: 10.1186/1472-6750-7-42  0.672
2006 Geurts AM, Wilber A, Carlson CM, Lobitz PD, Clark KJ, Hackett PB, McIvor RS, Largaespada DA. Conditional gene expression in the mouse using a Sleeping Beauty gene-trap transposon. Bmc Biotechnology. 6: 30. PMID 16800892 DOI: 10.1186/1472-6750-6-30  0.609
2005 Wadman SA, Clark KJ, Hackett PB. Fishing for answers with transposons. Marine Biotechnology (New York, N.Y.). 7: 135-41. PMID 15864468 DOI: 10.1007/S10126-004-0068-2  0.629
2005 Ohlfest JR, Frandsen JL, Fritz S, Lobitz PD, Perkinson SG, Clark KJ, Nelsestuen G, Key NS, McIvor RS, Hackett PB, Largaespada DA. Phenotypic correction and long-term expression of factor VIII in hemophilic mice by immunotolerization and nonviral gene transfer using the Sleeping Beauty transposon system. Blood. 105: 2691-8. PMID 15576475 DOI: 10.1182/Blood-2004-09-3496  0.617
2005 Wadman SA, Clark KJ, Hackett PB, McIvor RS, Essner JJ. 347. Long-Term Gene Expression and Phenotypic Correction of FANCC Deficient Lymphoblastoid Cells Using the Sleeping Beauty Transposon System Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.350  0.621
2005 Liu LN, Essner JJ, Shivakumar R, Li L, Wadman SA, Clark KJ, Nasevicious A, Fratantoni JC, McIvor RS, Hackett PB. 192. Non-Viral, Long-Term Gene Expression in Hematopoietic Cells Using the Sleeping Beauty Transposon System Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.195  0.605
2004 Larson JD, Wadman SA, Chen E, Kerley L, Clark KJ, Eide M, Lippert S, Nasevicius A, Ekker SC, Hackett PB, Essner JJ. Expression of VE-cadherin in zebrafish embryos: a new tool to evaluate vascular development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 231: 204-13. PMID 15305301 DOI: 10.1002/Dvdy.20102  0.765
2004 Clark KJ, Geurts AM, Bell JB, Hackett PB. Transposon vectors for gene-trap insertional mutagenesis in vertebrates. Genesis (New York, N.Y. : 2000). 39: 225-33. PMID 15286994 DOI: 10.1002/Gene.20049  0.642
2004 Ohlfest JR, Perkinson S, Lobitz P, Frandsen J, McIvor RS, Hackett P, Clark K, Essner J, Key N, Largaespada DA. 165. Long-term factor VIII expression and phenotypic correction in a murine model of hemophilia A achieved by immunosuppression and non-viral gene transfer using the sleeping beauty transposon Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.125  0.601
2003 Geurts AM, Yang Y, Clark KJ, Liu G, Cui Z, Dupuy AJ, Bell JB, Largaespada DA, Hackett PB. Gene transfer into genomes of human cells by the sleeping beauty transposon system. Molecular Therapy : the Journal of the American Society of Gene Therapy. 8: 108-17. PMID 12842434 DOI: 10.1016/S1525-0016(03)00099-6  0.696
2002 Dupuy AJ, Clark K, Carlson CM, Fritz S, Davidson AE, Markley KM, Finley K, Fletcher CF, Ekker SC, Hackett PB, Horn S, Largaespada DA. Mammalian germ-line transgenesis by transposition. Proceedings of the National Academy of Sciences of the United States of America. 99: 4495-9. PMID 11904379 DOI: 10.1073/Pnas.062630599  0.775
2001 Cui Z, Clark KJ, Kaufman CD, Hackett PB. Inhibition of skiA and skiB gene expression ventralizes zebrafish embryos. Genesis (New York, N.Y. : 2000). 30: 149-53. PMID 11477695 DOI: 10.1002/Gene.1052  0.594
1999 Fahrenkrug SC, Dahlquist MO, Clark KJ, Hackett PB. Dynamic and tissue-specific expression of eIF4E during zebrafish embryogenesis Differentiation. 65: 191-201. PMID 10653355 DOI: 10.1046/J.1432-0436.1999.6540191.X  0.736
1999 Fahrenkrug SC, Clark KJ, Dahlquist MO, Hackett PB. Dicistronic Gene Expression in Developing Zebrafish. Marine Biotechnology (New York, N.Y.). 1: 552-561. PMID 10612680 DOI: 10.1007/Pl00011810  0.735
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