Year |
Citation |
Score |
2013 |
Lis M, Bhatt S, Schoenly NE, Lee AY, Nislow C, Bobek LA. Chemical genomic screening of a Saccharomyces cerevisiae genomewide mutant collection reveals genes required for defense against four antimicrobial peptides derived from proteins found in human saliva. Antimicrobial Agents and Chemotherapy. 57: 840-7. PMID 23208710 DOI: 10.1128/Aac.01439-12 |
0.386 |
|
2012 |
Bernstein JM, Lehman H, Lis M, Sands A, Wilding GE, Shultz L, Bankert R, Bobek L. Humanized mouse model used to monitor MUC gene expression in nasal polyps and to preclinically evaluate the efficacy of montelukast in reducing mucus production. The Annals of Otology, Rhinology, and Laryngology. 121: 307-16. PMID 22724276 DOI: 10.1177/000348941212100505 |
0.362 |
|
2010 |
Lis M, Liu TT, Barker KS, Rogers PD, Bobek LA. Antimicrobial peptide MUC7 12-mer activates the calcium/calcineurin pathway in Candida albicans. Fems Yeast Research. 10: 579-86. PMID 20491945 DOI: 10.1111/J.1567-1364.2010.00638.X |
0.389 |
|
2009 |
Lis M, Fuss JR, Bobek LA. Exploring the mode of action of antimicrobial peptide MUC7 12-mer by fitness profiling of Saccharomyces cerevisiae genomewide mutant collection. Antimicrobial Agents and Chemotherapy. 53: 3762-9. PMID 19596888 DOI: 10.1128/Aac.00668-09 |
0.366 |
|
2008 |
Lis M, Bobek LA. Proteomic and metabolic characterization of a Candida albicans mutant resistant to the antimicrobial peptide MUC7 12-mer. Fems Immunology and Medical Microbiology. 54: 80-91. PMID 18680518 DOI: 10.1111/J.1574-695X.2008.00450.X |
0.333 |
|
2007 |
Wei GX, Campagna AN, Bobek LA. Factors affecting antimicrobial activity of MUC7 12-mer, a human salivary mucin-derived peptide. Annals of Clinical Microbiology and Antimicrobials. 6: 14. PMID 17996119 DOI: 10.1186/1476-0711-6-14 |
0.357 |
|
2006 |
Li S, Bobek LA. Functional analysis of human MUC7 mucin gene 5'-flanking region in lung epithelial cells. American Journal of Respiratory Cell and Molecular Biology. 35: 593-601. PMID 16778149 DOI: 10.1165/Rcmb.2006-0110Oc |
0.607 |
|
2006 |
Li S, Intini G, Bobek LA. Modulation of MUC7 mucin expression by exogenous factors in airway cells in vitro and in vivo. American Journal of Respiratory Cell and Molecular Biology. 35: 95-102. PMID 16514118 DOI: 10.1165/Rcmb.2005-0305Oc |
0.591 |
|
2005 |
Wei GX, Bobek LA. Human salivary mucin MUC7 12-mer-L and 12-mer-D peptides: antifungal activity in saliva, enhancement of activity with protease inhibitor cocktail or EDTA, and cytotoxicity to human cells. Antimicrobial Agents and Chemotherapy. 49: 2336-42. PMID 15917530 DOI: 10.1128/Aac.49.6.2336-2342.2005 |
0.35 |
|
2004 |
Wei GX, Bobek LA. In vitro synergic antifungal effect of MUC7 12-mer with histatin-5 12-mer or miconazole. The Journal of Antimicrobial Chemotherapy. 53: 750-8. PMID 15073161 DOI: 10.1093/Jac/Dkh181 |
0.363 |
|
2004 |
Intini G, Aguirre A, Bobek LA. Efficacy of human salivary mucin MUC7-derived peptide and histatin 5 in a murine model of candidiasis. International Journal of Antimicrobial Agents. 22: 594-600. PMID 14659657 DOI: 10.1016/S0924-8579(03)00243-7 |
0.322 |
|
2003 |
Situ H, Wei G, Smith CJ, Mashhoon S, Bobek LA. Human salivary MUC7 mucin peptides: effect of size, charge and cysteine residues on antifungal activity. The Biochemical Journal. 375: 175-82. PMID 12812519 DOI: 10.1042/Bj20030779 |
0.351 |
|
2003 |
Bobek LA, Situ H. MUC7 20-Mer: investigation of antimicrobial activity, secondary structure, and possible mechanism of antifungal action. Antimicrobial Agents and Chemotherapy. 47: 643-52. PMID 12543672 DOI: 10.1128/Aac.47.2.643-652.2003 |
0.339 |
|
2000 |
Situ H, Bobek LA. In vitro assessment of antifungal therapeutic potential of salivary histatin-5, two variants of histatin-5, and salivary mucin (MUC7) domain 1. Antimicrobial Agents and Chemotherapy. 44: 1485-93. PMID 10817697 DOI: 10.1128/Aac.44.6.1485-1493.2000 |
0.379 |
|
1999 |
Bobek LA, Li H, Rojstaczer N, Jones C, Gross KW, Levine MJ. Tissue-specific expression of human salivary mucin gene, MUC7, in transgenic mice. Transgenic Research. 7: 195-204. PMID 10461391 DOI: 10.1023/A:1008841013622 |
0.373 |
|
1999 |
Khan SH, Aguirre A, Bobek LA. In-situ hybridization localized MUC7 mucin gene expression to the mucous acinar cells of human and MUC7-transgenic mouse salivary glands. Glycoconjugate Journal. 15: 1125-32. PMID 10372967 DOI: 10.1023/A:1006955604501 |
0.384 |
|
1999 |
Situ H, Tsai H, Bobek LA. Construction and characterization of human salivary histatin-5 multimers. Journal of Dental Research. 78: 690-8. PMID 10029468 DOI: 10.1177/00220345990780020901 |
0.37 |
|
1999 |
Tsai H, Bobek LA. Human salivary histatins: promising anti-fungal therapeutic agents. Critical Reviews in Oral Biology and Medicine : An Official Publication of the American Association of Oral Biologists. 9: 480-97. PMID 9825223 DOI: 10.1177/10454411980090040601 |
0.302 |
|
1998 |
Weaver-Hiltke TR, Bobek LA. Transfection of COS cells with human cystatin cDNA and its effect on HSV-1 replication. Annals of the New York Academy of Sciences. 842: 204-8. PMID 9599312 DOI: 10.1111/J.1749-6632.1998.Tb09650.X |
0.302 |
|
1997 |
Tsai H, Bobek LA. Studies of the mechanism of human salivary histatin-5 candidacidal activity with histatin-5 variants and azole-sensitive and -resistant Candida species. Antimicrobial Agents and Chemotherapy. 41: 2224-8. PMID 9333052 DOI: 10.1128/Aac.41.10.2224 |
0.349 |
|
1997 |
Biesbrock AR, Bobek LA, Levine MJ. MUC7 gene expression and genetic polymorphism. Glycoconjugate Journal. 14: 415-22. PMID 9249138 DOI: 10.1023/A:1018587031814 |
0.385 |
|
1997 |
Bobek LA, Liu J, Sait SN, Shows TB, Bobek YA, Levine MJ. Structure and chromosomal localization of the human salivary mucin gene, MUC7. Genomics. 31: 277-82. PMID 8838308 DOI: 10.1006/Geno.1996.0049 |
0.385 |
|
1994 |
Bobek LA, Ramasubbu N, Wang X, Weaver TR, Levine MJ. Biological activities and secondary structures of variant forms of human salivary cystatin SN produced in Escherichia coli Gene. 151: 303-308. PMID 7828895 DOI: 10.1016/0378-1119(94)90675-0 |
0.347 |
|
1993 |
Bobek LA, Wang X, Levine MJ. Efficient production of biologically active human salivary cystatins in Escherichia coli. Gene. 123: 203-10. PMID 8428660 DOI: 10.1016/0378-1119(93)90125-M |
0.37 |
|
1993 |
Bobek LA, Tsai H, Levine MJ. Expression of human salivary histatin and cystatin/histatin chimeric cDNAs in Escherichia coli. Critical Reviews in Oral Biology and Medicine : An Official Publication of the American Association of Oral Biologists. 4: 581-90. PMID 8374011 DOI: 10.1177/10454411930040034501 |
0.391 |
|
1992 |
Reddy MS, Bobek LA, Haraszthy GG, Biesbrock AR, Levine MJ. Structural features of the low-molecular-mass human salivary mucin. The Biochemical Journal. 639-43. PMID 1445223 DOI: 10.1042/Bj2870639 |
0.362 |
|
1991 |
Bobek LA, Aguirre A, Levine MJ. Human salivary cystatin S. Cloning, sequence analysis, hybridization in situ and immunocytochemistry. The Biochemical Journal. 627-35. PMID 1898352 DOI: 10.1042/Bj2780627 |
0.431 |
|
1991 |
Mertz PM, Bobek LA, Rekosh DM, LoVerde PT. Schistosoma haematobium and S. japonicum: Analysis of the ribosomal RNA genes and determination of the "gap" boundaries and sequences Experimental Parasitology. 73: 137-149. PMID 1889469 DOI: 10.1016/0014-4894(91)90017-Q |
0.313 |
|
1991 |
Bobek LA, Rekosh DM, Lo Verde PT. Schistosoma japonicum: Analysis of eggshell protein genes, their expression, and comparison with similar genes from other schistosomes Experimental Parasitology. 72: 381-390. PMID 1709112 DOI: 10.1016/0014-4894(91)90084-A |
0.393 |
|
1990 |
Henkle KJ, Cook GA, Foster LA, Engman DM, Bobek LA, Cain GD, Donelson JE. The gene family encoding eggshell proteins of Schistosoma japonicum Molecular and Biochemical Parasitology. 42: 69-82. PMID 2172818 DOI: 10.1016/0166-6851(90)90114-2 |
0.381 |
|
1989 |
Bobek LA, LoVerde PT, Rekosh DM. Schistosoma haematobium: Analysis of eggshell protein genes and their expression Experimental Parasitology. 68: 17-30. PMID 2917627 DOI: 10.1016/0014-4894(89)90004-0 |
0.389 |
|
1989 |
LoVerde PT, Rekosh DM, Bobek LA. Developmentally regulated gene expression in Schistosoma Experimental Parasitology. 68: 116-120. PMID 2645161 DOI: 10.1016/0014-4894(89)90017-9 |
0.341 |
|
1988 |
Bobek LA, Rekosh DM, LoVerde PT. Small gene family encoding an eggshell (chorion) protein of the human parasite Schistosoma mansoni Molecular and Cellular Biology. 8: 3008-3016. PMID 2850476 DOI: 10.1128/Mcb.8.8.3008 |
0.387 |
|
1986 |
Bobek L, Rekosh DM, Van Keulen H, LoVerde PT. Characterization of a female-specific cDNA derived from a developmentally regulated mRNA in the human blood fluke Schistosoma mansoni Proceedings of the National Academy of Sciences of the United States of America. 83: 5544-5548. PMID 3461449 DOI: 10.1073/Pnas.83.15.5544 |
0.31 |
|
1985 |
Van Keulen H, Loverde PT, Bobek LA, Rekosh DM. Organization of the ribosomal RNA genes in Schistosoma mansoni Molecular and Biochemical Parasitology. 15: 215-230. PMID 4010707 DOI: 10.1016/0166-6851(85)90121-5 |
0.328 |
|
1983 |
Bobek LA, Bruenn JA, Field LJ, Gross KW. Cloning of cDNA to a yeast viral double-stranded RNA and comparison of three viral RNAs. Gene. 19: 225-30. PMID 6757056 DOI: 10.1016/0378-1119(82)90010-5 |
0.329 |
|
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