| Year |
Citation |
Score |
| 2023 |
Ung J, Tan SF, Fox TE, Shaw JJP, Taori M, Horton BJ, Golla U, Sharma A, Szulc ZM, Wang HG, Chalfant CE, Cabot MC, Claxton DF, Loughran TP, Feith DJ. Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia. Cancers. 15. PMID 38136410 DOI: 10.3390/cancers15245866 |
0.326 |
|
| 2023 |
Ung J, Tan SF, Fox TE, Shaw JJ, Taori M, Horton BJ, Golla U, Sharma A, Szulc ZM, Wang HG, Chalfant CE, Cabot MC, Claxton DF, Loughran TP, Feith DJ. Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia. Biorxiv : the Preprint Server For Biology. PMID 37961314 DOI: 10.1101/2023.10.21.563437 |
0.324 |
|
| 2023 |
Hattori T, Fundora KA, Hamamoto K, Opozda DM, Liang X, Liu X, Zhang J, Uzun Y, Takahashi Y, Wang HG. ER stress elicits non-canonical CASP8 (caspase 8) activation on autophagosomal membranes to induce apoptosis. Autophagy. 1-16. PMID 37733908 DOI: 10.1080/15548627.2023.2258701 |
0.41 |
|
| 2022 |
Hirschler-Laszkiewicz I, Festa F, Huang S, Moldovan GL, Nicolae C, Dhoonmoon A, Bao L, Keefer K, Chen SJ, Wang HG, Cheung JY, Miller BA. The human ion channel TRPM2 modulates cell survival in neuroblastoma through E2F1 and FOXM1. Scientific Reports. 12: 6311. PMID 35428820 DOI: 10.1038/s41598-022-10385-8 |
0.314 |
|
| 2020 |
Hattori T, Takahashi Y, Chen L, Tang Z, Wills CA, Liang X, Wang HG. Targeting the ESCRT-III component CHMP2A for noncanonical Caspase-8 activation on autophagosomal membranes. Cell Death and Differentiation. PMID 32807832 DOI: 10.1038/S41418-020-00610-0 |
0.527 |
|
| 2020 |
Gebru MT, Atkinson JM, Young M, Zhang L, Tang Z, Liu Z, Lu P, Dower C, Chen L, Annageldiyev C, Sharma A, Kawasawa Y, Zhao Z, Miller BA, Claxton D, ... Wang HG, et al. Glucocorticoids enhance the anti-leukemic activity of FLT3 inhibitors in FLT3 mutant acute myeloid leukemia. Blood. PMID 32396937 DOI: 10.1182/Blood.2019003124 |
0.367 |
|
| 2020 |
Chen SJ, Bao L, Keefer K, Shanmughapriya S, Chen L, Lee J, Wang J, Zhang XQ, Hirschler-Laszkiewicz I, Merali S, Merali C, Imamura Y, Dovat S, Madesh M, Cheung JY, ... Wang HG, et al. Transient receptor potential ion channel TRPM2 promotes AML proliferation and survival through modulation of mitochondrial function, ROS, and autophagy. Cell Death & Disease. 11: 247. PMID 32312983 DOI: 10.1038/S41419-020-2454-8 |
0.328 |
|
| 2019 |
Young MM, Bui V, Chen C, Wang HG. FTY720 induces non-canonical phosphatidylserine externalization and cell death in acute myeloid leukemia. Cell Death & Disease. 10: 847. PMID 31699964 DOI: 10.1038/S41419-019-2080-5 |
0.489 |
|
| 2019 |
Tang Z, Takahashi Y, He H, Hattori T, Chen C, Liang X, Chen H, Young MM, Wang HG. TOM40 Targets Atg2 to Mitochondria-Associated ER Membranes for Phagophore Expansion. Cell Reports. 28: 1744-1757.e5. PMID 31412244 DOI: 10.1016/J.Celrep.2019.07.036 |
0.411 |
|
| 2019 |
Li LX, Liu MY, Jiang X, Xia ZH, Wang YX, An D, Wang HG, Heng B, Liu YQ. Metformin inhibits Aβ -induced apoptotic cell death in SH-SY5Y cells. Basic & Clinical Pharmacology & Toxicology. PMID 31220411 DOI: 10.1111/bcpt.13279 |
0.319 |
|
| 2019 |
Morad SAF, MacDougall MR, Abdelmageed N, Kao LP, Feith DJ, Tan SF, Kester M, Loughran TP, Wang HG, Cabot MC. Pivotal role of mitophagy in response of acute myelogenous leukemia to a ceramide-tamoxifen-containing drug regimen. Experimental Cell Research. PMID 31112736 DOI: 10.1016/J.Yexcr.2019.05.021 |
0.34 |
|
| 2019 |
Tyndall ER, Ye Y, Tang Z, Wang H, Tian F. Protein-Lipid Interactions Regulate Atg3 Activity in Autophagy Biophysical Journal. 116: 517a-518a. DOI: 10.1016/J.Bpj.2018.11.2791 |
0.368 |
|
| 2018 |
Dower CM, Bhat N, Gebru MT, Chen L, Wills CA, Miller BA, Wang HG. Targeted inhibition of ULK1 promotes apoptosis and suppresses tumor growth and metastasis in neuroblastoma. Molecular Cancer Therapeutics. PMID 30166400 DOI: 10.1158/1535-7163.MCT-18-0176 |
0.331 |
|
| 2018 |
Liu Z, Wei Y, Zhang L, Yee PP, Johnson M, Zhang X, Gulley M, Atkinson JM, Trebak M, Wang HG, Li W. Induction of store-operated calcium entry (SOCE) suppresses glioblastoma growth by inhibiting the Hippo pathway transcriptional coactivators YAP/TAZ. Oncogene. PMID 30082911 DOI: 10.1038/S41388-018-0425-7 |
0.373 |
|
| 2018 |
Young MM, Wang HG. Sphingolipids as Regulators of Autophagy and Endocytic Trafficking. Advances in Cancer Research. 140: 27-60. PMID 30060813 DOI: 10.1016/bs.acr.2018.04.008 |
0.322 |
|
| 2018 |
Clements KE, Thakar T, Nicolae CM, Liang X, Wang HG, Moldovan GL. Loss of E2F7 confers resistance to poly-ADP-ribose polymerase (PARP) inhibitors in BRCA2-deficient cells. Nucleic Acids Research. PMID 30032296 DOI: 10.1093/nar/gky657 |
0.3 |
|
| 2018 |
Takahashi Y, He H, Tang Z, Hattori T, Liu Y, Young MM, Serfass JM, Chen L, Gebru M, Chen C, Wills CA, Atkinson JM, Chen H, Abraham T, Wang HG. An autophagy assay reveals the ESCRT-III component CHMP2A as a regulator of phagophore closure. Nature Communications. 9: 2855. PMID 30030437 DOI: 10.1038/s41467-018-05254-w |
0.319 |
|
| 2018 |
Dower CM, Wills CA, Frisch SM, Wang HG. Mechanisms and context underlying the role of autophagy in cancer metastasis. Autophagy. 1-19. PMID 29863947 DOI: 10.1080/15548627.2018.1450020 |
0.332 |
|
| 2018 |
Lima S, Takabe K, Newton J, Saurabh K, Young MM, Leopoldino AM, Hait NC, Roberts JL, Wang HG, Dent P, Milstien S, Booth L, Spiegel S. TP53 is required for BECN1- and ATG5-dependent cell death induced by sphingosine kinase 1 inhibition. Autophagy. 1-50. PMID 29368980 DOI: 10.1080/15548627.2018.1429875 |
0.543 |
|
| 2017 |
Tang Z, Takahashi Y, Chen C, Liu Y, He H, Tsotakos N, Serfass JM, Gebru MT, Chen H, Young MM, Wang HG. Atg2A/B deficiency switches cytoprotective autophagy to non-canonical caspase-8 activation and apoptosis. Cell Death and Differentiation. PMID 28800131 DOI: 10.1038/Cdd.2017.133 |
0.513 |
|
| 2017 |
LeBlanc FR, Yang J, Heller JH, Dighe S, Gru AA, Dunlap-Brown M, Wang H, Feith DJ, Loughran TP. Therapeutic Efficacy of Mcl-1 Antagonism in Large Granular Lymphocyte Leukemia Blood. 130: 1217-1217. DOI: 10.1182/Blood.V130.Suppl_1.1217.1217 |
0.417 |
|
| 2017 |
Li W, Liu Z, Xavier J, Wang H. Abstract 121: Identification and characterization of calcium channel blockers as inhibitors of YAP/TAZ and glioblastoma cells Cancer Research. 77: 121-121. DOI: 10.1158/1538-7445.Am2017-121 |
0.442 |
|
| 2017 |
Shin D, Kim YS, Shimko S, Wang H, Phaeton R, Hempel N. Mitochondrial Function is Dynamically Regulated during Ovarian Cancer Progression through Alterations in Fusion/Fission Free Radical Biology and Medicine. 112: 99-100. DOI: 10.1016/J.Freeradbiomed.2017.10.149 |
0.383 |
|
| 2016 |
Dower CM, Bhat N, Wang EW, Wang HG. Selective Reversible Inhibition of Autophagy in Hypoxic Breast Cancer Cells Promotes Pulmonary Metastasis. Cancer Research. PMID 28115361 DOI: 10.1158/0008-5472.Can-15-3458 |
0.454 |
|
| 2016 |
Young MM, Takahashi Y, Fox TE, Yun JK, Kester M, Wang HG. Sphingosine Kinase 1 Cooperates with Autophagy to Maintain Endocytic Membrane Trafficking. Cell Reports. 17: 1532-1545. PMID 27806293 DOI: 10.1016/J.Celrep.2016.10.019 |
0.328 |
|
| 2016 |
Zhang C, Liu F, Chen H, Li N, Luo Z, Guo W, Huang D, Tang S, Wang H, Cheng S, Li Z, Wang H. Bif-1 promotes tumor cell migration and metastasis via Cdc42 expression and activity. Clinical & Experimental Metastasis. PMID 27730394 DOI: 10.1007/S10585-016-9825-7 |
0.343 |
|
| 2016 |
Bao L, Chen SJ, Conrad K, Keefer K, Abraham T, Lee JP, Wang J, Zhang XQ, Hirschler-Laszkiewicz I, Wang HG, Dovat S, Gans B, Madesh M, Cheung JY, Miller BA. Depletion of the Human Ion Channel TRPM2 in Neuroblastoma Demonstrates its Key Role in Cell Survival through Modulation of Mitochondrial ROS and Bioenergetics. The Journal of Biological Chemistry. PMID 27694440 DOI: 10.1074/Jbc.M116.747147 |
0.41 |
|
| 2016 |
Liu Q, Chen L, Atkinson JM, Claxton DF, Wang HG. Atg5-dependent autophagy contributes to the development of acute myeloid leukemia in an MLL-AF9-driven mouse model. Cell Death & Disease. 7: e2361. PMID 27607576 DOI: 10.1038/Cddis.2016.264 |
0.383 |
|
| 2016 |
Takahashi Y, Tsotakos N, Liu Y, Young MM, Serfass J, Tang Z, Abraham T, Wang HG. The Bif-1-Dynamin 2 membrane fission machinery regulates Atg9-containing vesicle generation at the Rab11-positive reservoirs. Oncotarget. PMID 26980706 DOI: 10.18632/oncotarget.8028 |
0.359 |
|
| 2016 |
Liu Y, Takahashi Y, Desai N, Zhang J, Serfass JM, Shi YG, Lynch CJ, Wang HG. Bif-1 deficiency impairs lipid homeostasis and causes obesity accompanied by insulin resistance. Scientific Reports. 6: 20453. PMID 26857140 DOI: 10.1038/Srep20453 |
0.306 |
|
| 2016 |
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... Wang HJ, ... Wang H, ... Wang HG, ... Wang H, ... Wang HD, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356 |
0.366 |
|
| 2016 |
Dower CM, Wang H. Abstract 5110: The role of autophagy in the tumor microenvironment Cancer Research. 76: 5110-5110. DOI: 10.1158/1538-7445.Am2016-5110 |
0.398 |
|
| 2016 |
Liu Q, Chen L, Wang H. Abstract 3531: Autophagy facilitates leukemogenesis in a murine model of MLL-AF9-driven AML Cancer Research. 76: 3531-3531. DOI: 10.1158/1538-7445.Am2016-3531 |
0.427 |
|
| 2016 |
Tang Z, Takahashi Y, Wang H. Abstract 3527: Inhibition of autophagosome closure promotes iDISC-mediated apoptosis in AML cells Cancer Research. 76: 3527-3527. DOI: 10.1158/1538-7445.Am2016-3527 |
0.472 |
|
| 2015 |
Varadarajan S, Poornima P, Milani M, Gowda K, Amin S, Wang HG, Cohen GM. Maritoclax and dinaciclib inhibit MCL-1 activity and induce apoptosis in both a MCL-1-dependent and -independent manner. Oncotarget. 6: 12668-81. PMID 26059440 DOI: 10.18632/Oncotarget.3706 |
0.35 |
|
| 2015 |
Niu G, Zhang H, Liu D, Chen L, Belani C, Wang HG, Cheng H. Tid1, the Mammalian Homologue of Drosophila Tumor Suppressor Tid56, Mediates Macroautophagy by Interacting with Beclin1-containing Autophagy Protein Complex. The Journal of Biological Chemistry. 290: 18102-10. PMID 26055714 DOI: 10.1074/Jbc.M115.665950 |
0.473 |
|
| 2015 |
Hsu P, Liu X, Zhang J, Wang HG, Ye JM, Shi Y. Cardiolipin remodeling by TAZ/tafazzin is selectively required for the initiation of mitophagy. Autophagy. 11: 643-52. PMID 25919711 DOI: 10.1080/15548627.2015.1023984 |
0.315 |
|
| 2015 |
Dick TE, Hengst JA, Fox TE, Colledge AL, Kale VP, Sung SS, Sharma A, Amin S, Loughran TP, Kester M, Wang HG, Yun JK. The apoptotic mechanism of action of the sphingosine kinase 1 selective inhibitor SKI-178 in human acute myeloid leukemia cell lines. The Journal of Pharmacology and Experimental Therapeutics. 352: 494-508. PMID 25563902 DOI: 10.1124/Jpet.114.219659 |
0.386 |
|
| 2015 |
Sun X, Hasanali ZS, Chen A, Zhang D, Liu X, Wang HG, Feith DJ, Loughran TP, Xu K. Suberoylanilide hydroxamic acid (SAHA) and cladribine synergistically induce apoptosis in NK-LGL leukaemia. British Journal of Haematology. 168: 371-83. PMID 25284154 DOI: 10.1111/Bjh.13143 |
0.391 |
|
| 2015 |
Ren T, Takahashi Y, Liu X, Loughran TP, Sun SC, Wang HG, Cheng H. HTLV-1 Tax deregulates autophagy by recruiting autophagic molecules into lipid raft microdomains. Oncogene. 34: 334-45. PMID 24362528 DOI: 10.1038/Onc.2013.552 |
0.39 |
|
| 2015 |
Arsiwala S, Ding W, Wang H. Selective Deletion of ATG5 in Bone Marrow Leptin-Receptor-Expressing Perivascular Stromal Cells Causes Leukopenia Blood. 126: 2395-2395. DOI: 10.1182/Blood.V126.23.2395.2395 |
0.368 |
|
| 2015 |
LeBlanc FR, Wang H, Feith DJ, Loughran TP. FTY720 (Fingolimod) Targets the Sphingolipid Pathway and Induces Autophagy-Related Apoptosis in Human Natural Killer Large Granular Lymphocyte Leukemia Blood. 126: 1288-1288. DOI: 10.1182/Blood.V126.23.1288.1288 |
0.491 |
|
| 2015 |
Wang W, Dicker DT, Claxton DF, Wang H, El-Deiry WS. Abstract 3486: Synergistic effect of quinacrine in combination with decitabine for the treatment of acute myeloid leukemia cellsin vitro: implication for treatment of AML in the elderly Cancer Research. 75: 3486-3486. DOI: 10.1158/1538-7445.Am2015-3486 |
0.444 |
|
| 2014 |
Barth BM, Keasey NR, Wang X, Shanmugavelandy SS, Rampal R, Hricik T, Cabot MC, Kester M, Wang HG, Shultz LD, Tallman MS, Levine RL, Loughran TP, Claxton DF. Engraftment of Human Primary Acute Myeloid Leukemia Defined by Integrated Genetic Profiling in NOD/SCID/IL2rγnull Mice for Preclinical Ceramide-Based Therapeutic Evaluation. Journal of Leukemia (Los Angeles, Calif.). 2. PMID 28239612 DOI: 10.4172/2329-6917.1000146 |
0.316 |
|
| 2014 |
Doi K, Gowda K, Liu Q, Lin JM, Sung SS, Dower C, Claxton D, Loughran TP, Amin S, Wang HG. Pyoluteorin derivatives induce Mcl-1 degradation and apoptosis in hematological cancer cells. Cancer Biology & Therapy. 15: 1688-99. PMID 25535900 DOI: 10.4161/15384047.2014.972799 |
0.458 |
|
| 2014 |
Chen SJ, Hoffman NE, Shanmughapriya S, Bao L, Keefer K, Conrad K, Merali S, Takahashi Y, Abraham T, Hirschler-Laszkiewicz I, Wang J, Zhang XQ, Song J, Barrero C, Shi Y, ... ... Wang HG, et al. A splice variant of the human ion channel TRPM2 modulates neuroblastoma tumor growth through hypoxia-inducible factor (HIF)-1/2α. The Journal of Biological Chemistry. 289: 36284-302. PMID 25391657 DOI: 10.1074/Jbc.M114.620922 |
0.361 |
|
| 2014 |
Doi K, Liu Q, Gowda K, Barth BM, Claxton D, Amin S, Loughran TP, Wang HG. Maritoclax induces apoptosis in acute myeloid leukemia cells with elevated Mcl-1 expression. Cancer Biology & Therapy. 15: 1077-86. PMID 24842334 DOI: 10.4161/Cbt.29186 |
0.413 |
|
| 2014 |
Muppidi A, Doi K, Edwardraja S, Pulavarti SV, Szyperski T, Wang HG, Lin Q. Targeted delivery of ubiquitin-conjugated BH3 peptide-based Mcl-1 inhibitors into cancer cells. Bioconjugate Chemistry. 25: 424-32. PMID 24410055 DOI: 10.1021/Bc4005574 |
0.32 |
|
| 2014 |
Tan S, Liu X, Doi K, Wang H, Cabot M, Feith D, Loughran TP. Abstract 761: Acid ceramidase promotes drug resistance in acute myeloid leukemia through P-gp upregulation mediated by NF- kB activation Cancer Research. 74: 761-761. DOI: 10.1158/1538-7445.Am2014-761 |
0.338 |
|
| 2014 |
Liu Q, Doi K, Gowda K, Barth BM, Claxton D, Amin S, Loughran TP, Wang H. Abstract 1807: Pre-clinical evaluation of Mcl-1 inhibition through maritoclax in acute myeloid leukemia Cancer Research. 74: 1807-1807. DOI: 10.1158/1538-7445.Am2014-1807 |
0.463 |
|
| 2014 |
Doi K, Gowda K, Liu Q, Sung S, Lin JM, Amin S, Loughran TP, Wang H. Abstract 1805: Characterization of pyoluteorin derivatives as Mcl-1 antagonists Cancer Research. 74: 1805-1805. DOI: 10.1158/1538-7445.Am2014-1805 |
0.463 |
|
| 2013 |
Ryland LK, Doshi UA, Shanmugavelandy SS, Fox TE, Aliaga C, Broeg K, Baab KT, Young M, Khan O, Haakenson JK, Jarbadan NR, Liao J, Wang HG, Feith DJ, Loughran TP, et al. C6-ceramide nanoliposomes target the Warburg effect in chronic lymphocytic leukemia. Plos One. 8: e84648. PMID 24367685 DOI: 10.1371/Journal.Pone.0084648 |
0.436 |
|
| 2013 |
Pandey MK, Gowda K, Doi K, Sharma AK, Wang HG, Amin S. Proteasomal degradation of Mcl-1 by maritoclax induces apoptosis and enhances the efficacy of ABT-737 in melanoma cells. Plos One. 8: e78570. PMID 24223823 DOI: 10.1371/Journal.Pone.0078570 |
0.466 |
|
| 2013 |
He S, Ni D, Ma B, Lee JH, Zhang T, Ghozalli I, Pirooz SD, Zhao Z, Bharatham N, Li B, Oh S, Lee WH, Takahashi Y, Wang HG, Minassian A, et al. PtdIns(3)P-bound UVRAG coordinates Golgi-ER retrograde and Atg9 transport by differential interactions with the ER tether and the beclin 1 complex. Nature Cell Biology. 15: 1206-19. PMID 24056303 DOI: 10.1038/Ncb2848 |
0.391 |
|
| 2013 |
Takahashi Y, Young MM, Serfass JM, Hori T, Wang HG. Sh3glb1/Bif-1 and mitophagy: acquisition of apoptosis resistance during Myc-driven lymphomagenesis. Autophagy. 9: 1107-9. PMID 23680845 DOI: 10.4161/Auto.24817 |
0.528 |
|
| 2013 |
Yang Y, Fiskus W, Yong B, Atadja P, Takahashi Y, Pandita TK, Wang HG, Bhalla KN. Acetylated hsp70 and KAP1-mediated Vps34 SUMOylation is required for autophagosome creation in autophagy. Proceedings of the National Academy of Sciences of the United States of America. 110: 6841-6. PMID 23569248 DOI: 10.1073/Pnas.1217692110 |
0.37 |
|
| 2013 |
Takahashi Y, Hori T, Cooper TK, Liao J, Desai N, Serfass JM, Young MM, Park S, Izu Y, Wang HG. Bif-1 haploinsufficiency promotes chromosomal instability and accelerates Myc-driven lymphomagenesis via suppression of mitophagy. Blood. 121: 1622-32. PMID 23287860 DOI: 10.1182/Blood-2012-10-459826 |
0.461 |
|
| 2013 |
Takahashi Y, Young MM, Wang HG. SNAPping off Golgi membranes for autophagosome formation. Cell Cycle (Georgetown, Tex.). 12: 15-6. PMID 23255097 DOI: 10.4161/Cc.23174 |
0.54 |
|
| 2013 |
Young MM, Kester M, Wang HG. Sphingolipids: regulators of crosstalk between apoptosis and autophagy. Journal of Lipid Research. 54: 5-19. PMID 23152582 DOI: 10.1194/Jlr.R031278 |
0.482 |
|
| 2013 |
Wei S, Chen X, McGraw K, Zhang L, Komrokji R, Clark J, Caceres G, Billingsley D, Sokol L, Lancet J, Fortenbery N, Zhou J, Eksioglu EA, Sallman D, Wang H, et al. Lenalidomide promotes p53 degradation by inhibiting MDM2 auto-ubiquitination in myelodysplastic syndrome with chromosome 5q deletion. Oncogene. 32: 1110-20. PMID 22525275 DOI: 10.1038/Onc.2012.139 |
0.305 |
|
| 2013 |
Pandey MK, Gowda K, Doi K, Sharma A, Wang H, Amin S. Abstract 1720: Maritoclax, a selective Mcl-1 inhibitor, sensitizes melanoma cells to the Bad BH3-mimetic ABT-737. Cancer Research. 73: 1720-1720. DOI: 10.1158/1538-7445.Am2013-1720 |
0.45 |
|
| 2013 |
Ren T, Dong W, Takahashi Y, Loughran TP, Sun S, Wang H, Cheng H. Abstract 1067: HTLV-1 Tax deregulates autophagy in promoting T-cell survival and proliferation. Cancer Research. 73: 1067-1067. DOI: 10.1158/1538-7445.Am2013-1067 |
0.471 |
|
| 2012 |
Liu Q, Wang HG. Anti-cancer drug discovery and development: Bcl-2 family small molecule inhibitors. Communicative & Integrative Biology. 5: 557-65. PMID 23336025 DOI: 10.4161/Cib.21554 |
0.39 |
|
| 2012 |
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Wang H, ... ... Wang HG, ... ... Wang HD, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496 |
0.323 |
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| 2012 |
Kim YB, Balasis ME, Doi K, Berndt N, DuBoulay C, Hu CC, Guida W, Wang HG, Sebti SM, Del Valle JR. Synthesis and evaluation of substituted hexahydronaphthalenes as novel inhibitors of the Mcl-1/BimBH3 interaction. Bioorganic & Medicinal Chemistry Letters. 22: 5961-5. PMID 22901384 DOI: 10.1016/J.Bmcl.2012.07.050 |
0.375 |
|
| 2012 |
Runkle KB, Meyerkord CL, Desai NV, Takahashi Y, Wang HG. Bif-1 suppresses breast cancer cell migration by promoting EGFR endocytic degradation. Cancer Biology & Therapy. 13: 956-66. PMID 22785202 DOI: 10.4161/Cbt.20951 |
0.764 |
|
| 2012 |
Zhang Y, Cheng Y, Ren X, Hori T, Huber-Keener KJ, Zhang L, Yap KL, Liu D, Shantz L, Qin ZH, Zhang S, Wang J, Wang HG, Shih IeM, Yang JM. Dysfunction of nucleus accumbens-1 activates cellular senescence and inhibits tumor cell proliferation and oncogenesis. Cancer Research. 72: 4262-75. PMID 22665267 DOI: 10.1158/0008-5472.Can-12-0139 |
0.329 |
|
| 2012 |
Young MM, Takahashi Y, Khan O, Park S, Hori T, Yun J, Sharma AK, Amin S, Hu CD, Zhang J, Kester M, Wang HG. Autophagosomal membrane serves as platform for intracellular death-inducing signaling complex (iDISC)-mediated caspase-8 activation and apoptosis. The Journal of Biological Chemistry. 287: 12455-68. PMID 22362782 DOI: 10.1074/Jbc.M111.309104 |
0.507 |
|
| 2011 |
Zhang Y, Cheng Y, Zhang L, Ren X, Huber-Keener KJ, Lee S, Yun J, Wang HG, Yang JM. Inhibition of eEF-2 kinase sensitizes human glioma cells to TRAIL and down-regulates Bcl-xL expression. Biochemical and Biophysical Research Communications. 414: 129-34. PMID 21945617 DOI: 10.1016/J.Bbrc.2011.09.038 |
0.48 |
|
| 2011 |
Liao A, Broeg K, Fox T, Tan SF, Watters R, Shah MV, Zhang LQ, Li Y, Ryland L, Yang J, Aliaga C, Dewey A, Rogers A, Loughran K, Hirsch L, ... ... Wang HG, et al. Therapeutic efficacy of FTY720 in a rat model of NK-cell leukemia. Blood. 118: 2793-800. PMID 21768294 DOI: 10.1182/Blood-2011-01-331447 |
0.413 |
|
| 2011 |
Watters RJ, Wang HG, Sung SS, Loughran TP, Liu X. Targeting sphingosine-1-phosphate receptors in cancer. Anti-Cancer Agents in Medicinal Chemistry. 11: 810-7. PMID 21707490 DOI: 10.2174/187152011797655041 |
0.353 |
|
| 2011 |
Kulkarni SS, Hu X, Doi K, Wang HG, Manetsch R. Screening of protein-protein interaction modulators via sulfo-click kinetic target-guided synthesis. Acs Chemical Biology. 6: 724-32. PMID 21506574 DOI: 10.1021/Cb200085Q |
0.308 |
|
| 2011 |
Coppola D, Helm J, Ghayouri M, Malafa MP, Wang HG. Down-regulation of Bax-interacting factor 1 in human pancreatic ductal adenocarcinoma. Pancreas. 40: 433-7. PMID 21283040 DOI: 10.1097/Mpa.0B013E318205Eb03 |
0.382 |
|
| 2011 |
Kazi A, Sun J, Doi K, Sung SS, Takahashi Y, Yin H, Rodriguez JM, Becerril J, Berndt N, Hamilton AD, Wang HG, Sebti SM. The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner. The Journal of Biological Chemistry. 286: 9382-92. PMID 21148306 DOI: 10.1074/Jbc.M110.203638 |
0.325 |
|
| 2011 |
Takahashi Y, Meyerkord CL, Hori T, Runkle K, Fox TE, Kester M, Loughran TP, Wang HG. Bif-1 regulates Atg9 trafficking by mediating the fission of Golgi membranes during autophagy. Autophagy. 7: 61-73. PMID 21068542 DOI: 10.4161/Auto.7.1.14015 |
0.792 |
|
| 2011 |
Runkle KB, Takahashi Y, Wang H. Abstract LB-99: Bif-1 promotes EGFR endocytic degradation and contributes to suppression of metastatic potential in breast and colon cancers Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-99 |
0.448 |
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| 2011 |
Pernazza D, Doi K, Lawrence H, Sebti S, Wang H, Lawrence N. Abstract 1354: New chemical tools for disrupting the Mcl-1/BH3 protein-protein interaction Cancer Research. 71: 1354-1354. DOI: 10.1158/1538-7445.Am2011-1354 |
0.394 |
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| 2010 |
Lee JW, Park S, Takahashi Y, Wang HG. The association of AMPK with ULK1 regulates autophagy. Plos One. 5: e15394. PMID 21072212 DOI: 10.1371/Journal.Pone.0015394 |
0.46 |
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| 2010 |
Yang J, Takahashi Y, Cheng E, Liu J, Terranova PF, Zhao B, Thrasher JB, Wang HG, Li B. GSK-3beta promotes cell survival by modulating Bif-1-dependent autophagy and cell death. Journal of Cell Science. 123: 861-70. PMID 20159967 DOI: 10.1242/Jcs.060475 |
0.381 |
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| 2010 |
Pernazza D, Lawrence HR, Doi K, Sung S, Guida WC, Sebti SM, Wang H, Lawrence NJ. Abstract 732: Targeting the Bcl-2/BH3 protein-protein interaction: Identification, design, and synthesis of new selective inhibitors of the Mcl-1/BH3 interaction Cancer Research. 70: 732-732. DOI: 10.1158/1538-7445.Am10-732 |
0.397 |
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| 2010 |
Takahashi Y, Meyerkord CL, Gonsar K, Hori T, Wang H. Abstract 4835: Bif-1 induces the fission of Golgi membranes to generate Atg9-containing vesicles for autophagosome formation Cancer Research. 70: 4835-4835. DOI: 10.1158/1538-7445.Am10-4835 |
0.782 |
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| 2010 |
Park S, Komine K, Takahashi Y, Wang H. Abstract 1262: Bif-1 is required for keeping mitochondrial and lysosomal positive feedback loops in check to prevent apoptosis induced by death receptors in type II cells Cellular and Molecular Biology. 70: 1262-1262. DOI: 10.1158/1538-7445.Am10-1262 |
0.402 |
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| 2009 |
Wei J, Kitada S, Rega MF, Emdadi A, Yuan H, Cellitti J, Stebbins JL, Zhai D, Sun J, Yang L, Dahl R, Zhang Z, Wu B, Wang S, Reed TA, ... Wang HG, et al. Apogossypol derivatives as antagonists of antiapoptotic Bcl-2 family proteins. Molecular Cancer Therapeutics. 8: 904-13. PMID 19372563 DOI: 10.1158/1535-7163.Mct-08-1050 |
0.303 |
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| 2009 |
Takahashi Y, Meyerkord CL, Wang HG. Bif-1/endophilin B1: a candidate for crescent driving force in autophagy. Cell Death and Differentiation. 16: 947-55. PMID 19265852 DOI: 10.1038/Cdd.2009.19 |
0.782 |
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| 2009 |
Yamaguchi H, Woods NT, Piluso LG, Lee HH, Chen J, Bhalla KN, Monteiro A, Liu X, Hung MC, Wang HG. p53 acetylation is crucial for its transcription-independent proapoptotic functions. The Journal of Biological Chemistry. 284: 11171-83. PMID 19265193 DOI: 10.1074/Jbc.M809268200 |
0.732 |
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| 2009 |
Etxebarria A, Terrones O, Yamaguchi H, Landajuela A, Landeta O, Antonsson B, Wang HG, Basañez G. Endophilin B1/Bif-1 stimulates BAX activation independently from its capacity to produce large scale membrane morphological rearrangements. The Journal of Biological Chemistry. 284: 4200-12. PMID 19074440 DOI: 10.1074/jbc.M808050200 |
0.347 |
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| 2008 |
Coppola D, Khalil F, Eschrich SA, Boulware D, Yeatman T, Wang HG. Down-regulation of Bax-interacting factor-1 in colorectal adenocarcinoma. Cancer. 113: 2665-70. PMID 18833585 DOI: 10.1002/Cncr.23892 |
0.419 |
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| 2008 |
Hu X, Sun J, Wang HG, Manetsch R. Bcl-XL-templated assembly of its own protein-protein interaction modulator from fragments decorated with thio acids and sulfonyl azides. Journal of the American Chemical Society. 130: 13820-1. PMID 18811158 DOI: 10.1021/Ja802683U |
0.326 |
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| 2008 |
Meyerkord CL, Takahashi Y, Araya R, Takada N, Weiss RS, Wang HG. Loss of Hus1 sensitizes cells to etoposide-induced apoptosis by regulating BH3-only proteins. Oncogene. 27: 7248-59. PMID 18794804 DOI: 10.1038/onc.2008.336 |
0.796 |
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| 2008 |
Yamaguchi H, Woods NT, Dorsey JF, Takahashi Y, Gjertsen NR, Yeatman T, Wu J, Wang HG. SRC directly phosphorylates Bif-1 and prevents its interaction with Bax and the initiation of anoikis. The Journal of Biological Chemistry. 283: 19112-8. PMID 18474606 DOI: 10.1074/Jbc.M709882200 |
0.683 |
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| 2008 |
Li CG, Gruidl M, Eschrich S, McCarthy S, Wang HG, Alexandrow MG, Yeatman TJ. Insig2 is associated with colon tumorigenesis and inhibits Bax-mediated apoptosis. International Journal of Cancer. Journal International Du Cancer. 123: 273-82. PMID 18464289 DOI: 10.1002/Ijc.23510 |
0.493 |
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| 2008 |
Oliveira V, Romanow WJ, Geisen C, Otterness DM, Mercurio F, Wang HG, Dalton WS, Abraham RT. A protective role for the human SMG-1 kinase against tumor necrosis factor-alpha-induced apoptosis. The Journal of Biological Chemistry. 283: 13174-84. PMID 18326048 DOI: 10.1074/jbc.M708008200 |
0.379 |
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| 2008 |
Sun A, Tang J, Hong Y, Song J, Terranova PF, Thrasher JB, Svojanovsky S, Wang HG, Li B. Androgen receptor-dependent regulation of Bcl-xL expression: Implication in prostate cancer progression. The Prostate. 68: 453-61. PMID 18196538 DOI: 10.1002/Pros.20723 |
0.389 |
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| 2008 |
Takahashi Y, Meyerkord CL, Wang HG. BARgaining membranes for autophagosome formation: Regulation of autophagy and tumorigenesis by Bif-1/Endophilin B1. Autophagy. 4: 121-4. PMID 18032918 DOI: 10.4161/Auto.5265 |
0.799 |
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| 2007 |
Woods NT, Yamaguchi H, Lee FY, Bhalla KN, Wang HG. Anoikis, initiated by Mcl-1 degradation and Bim induction, is deregulated during oncogenesis. Cancer Research. 67: 10744-52. PMID 18006817 DOI: 10.1158/0008-5472.Can-07-3148 |
0.728 |
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| 2007 |
Ren Y, Chen Z, Chen L, Woods NT, Reuther GW, Cheng JQ, Wang HG, Wu J. Shp2E76K mutant confers cytokine-independent survival of TF-1 myeloid cells by up-regulating Bcl-XL. The Journal of Biological Chemistry. 282: 36463-73. PMID 17942397 DOI: 10.1074/Jbc.M705789200 |
0.724 |
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| 2007 |
Takahashi Y, Coppola D, Matsushita N, Cualing HD, Sun M, Sato Y, Liang C, Jung JU, Cheng JQ, Mulé JJ, Pledger WJ, Wang HG. Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis. Nature Cell Biology. 9: 1142-51. PMID 17891140 DOI: 10.1038/Ncb1634 |
0.476 |
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| 2006 |
Yamaguchi H, Wang HG. Tissue transglutaminase serves as an inhibitor of apoptosis by cross-linking caspase 3 in thapsigargin-treated cells. Molecular and Cellular Biology. 26: 569-79. PMID 16382148 DOI: 10.1128/MCB.26.2.569-579.2006 |
0.359 |
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| 2005 |
Takahashi Y, Karbowski M, Yamaguchi H, Kazi A, Wu J, Sebti SM, Youle RJ, Wang HG. Loss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosis. Molecular and Cellular Biology. 25: 9369-82. PMID 16227588 DOI: 10.1128/Mcb.25.21.9369-9382.2005 |
0.378 |
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| 2005 |
Zhang X, Li P, Bao J, Nicosia SV, Wang H, Enkemann SA, Bai W. Suppression of death receptor-mediated apoptosis by 1,25-dihydroxyvitamin D3 revealed by microarray analysis. The Journal of Biological Chemistry. 280: 35458-68. PMID 16093247 DOI: 10.1074/Jbc.M506648200 |
0.405 |
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| 2005 |
Zheng Y, Yamaguchi H, Tian C, Lee MW, Tang H, Wang HG, Chen Q. Arsenic trioxide (As(2)O(3)) induces apoptosis through activation of Bax in hematopoietic cells. Oncogene. 24: 3339-47. PMID 15735709 DOI: 10.1038/Sj.Onc.1208484 |
0.317 |
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| 2005 |
Araya R, Hirai I, Meyerkord CL, Wang HG. Loss of RPA1 induces Chk2 phosphorylation through a caffeine-sensitive pathway. Febs Letters. 579: 157-61. PMID 15620706 DOI: 10.1016/J.Febslet.2004.11.066 |
0.774 |
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| 2004 |
Yamaguchi H, Wang HG. CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells. The Journal of Biological Chemistry. 279: 45495-502. PMID 15322075 DOI: 10.1074/JBC.M406933200 |
0.381 |
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| 2004 |
Yamaguchi H, Chen J, Bhalla K, Wang HG. Regulation of Bax activation and apoptotic response to microtubule-damaging agents by p53 transcription-dependent and -independent pathways. The Journal of Biological Chemistry. 279: 39431-7. PMID 15262986 DOI: 10.1074/Jbc.M401530200 |
0.393 |
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| 2004 |
Terrones O, Antonsson B, Yamaguchi H, Wang HG, Liu J, Lee RM, Herrmann A, Basañez G. Lipidic pore formation by the concerted action of proapoptotic BAX and tBID. The Journal of Biological Chemistry. 279: 30081-91. PMID 15138279 DOI: 10.1074/Jbc.M313420200 |
0.319 |
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| 2004 |
Hirai I, Sasaki T, Wang H. Human hRad1 but not hRad9 protects hHus1 from ubiquitin-proteasomal degradation. Oncogene. 23: 5124-5130. PMID 15122316 DOI: 10.1038/Sj.Onc.1207658 |
0.397 |
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| 2004 |
Dan HC, Sun M, Kaneko S, Feldman RI, Nicosia SV, Wang HG, Tsang BK, Cheng JQ. Akt phosphorylation and stabilization of X-linked inhibitor of apoptosis protein (XIAP). The Journal of Biological Chemistry. 279: 5405-12. PMID 14645242 DOI: 10.1074/Jbc.M312044200 |
0.518 |
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| 2003 |
Terajima D, Yamada S, Uchino R, Ikawa S, Ikeda M, Shida K, Arai Y, Wang H, Satoh N, Satake M. Identification and sequence of seventy-nine new transcripts expressed in hemocytes of Ciona intestinalis, three of which may be involved in characteristic cell-cell communication. Dna Research. 10: 203-212. PMID 14686582 DOI: 10.1093/Dnares/10.5.203 |
0.305 |
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| 2003 |
Fuino L, Bali P, Wittmann S, Donapaty S, Guo F, Yamaguchi H, Wang HG, Atadja P, Bhalla K. Histone deacetylase inhibitor LAQ824 down-regulates Her-2 and sensitizes human breast cancer cells to trastuzumab, taxotere, gemcitabine, and epothilone B. Molecular Cancer Therapeutics. 2: 971-84. PMID 14578462 |
0.359 |
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| 2003 |
Lee MW, Hirai I, Wang HG. Caspase-3-mediated cleavage of Rad9 during apoptosis. Oncogene. 22: 6340-6. PMID 14508514 DOI: 10.1038/sj.onc.1206729 |
0.384 |
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| 2003 |
Chen T, Yang I, Irby R, Shain KH, Wang HG, Quackenbush J, Coppola D, Cheng JQ, Yeatman TJ. Regulation of caspase expression and apoptosis by adenomatous polyposis coli Cancer Research. 63: 4368-4374. PMID 12907606 |
0.371 |
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| 2003 |
Yamaguchi H, Bhalla K, Wang HG. Bax plays a pivotal role in thapsigargin-induced apoptosis of human colon cancer HCT116 cells by controlling Smac/Diablo and Omi/HtrA2 release from mitochondria. Cancer Research. 63: 1483-9. PMID 12670894 |
0.37 |
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| 2003 |
Yoshida K, Wang H, Miki Y, Kufe D. Protein kinase Cδ is responsible for constitutive and DNA damage‐induced phosphorylation of Rad9 The Embo Journal. 22: 1431-1441. PMID 12628935 DOI: 10.1093/Emboj/Cdg134 |
0.426 |
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| 2003 |
Nimmanapalli R, O'Bryan E, Kuhn D, Yamaguchi H, Wang HG, Bhalla KN. Regulation of 17-AAG-induced apoptosis: role of Bcl-2, Bcl-XL, and Bax downstream of 17-AAG-mediated down-regulation of Akt, Raf-1, and Src kinases. Blood. 102: 269-75. PMID 12623837 DOI: 10.1182/Blood-2002-12-3718 |
0.393 |
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| 2003 |
Wittmann S, Bali P, Donapaty S, Nimmanapalli R, Guo F, Yamaguchi H, Huang M, Jove R, Wang HG, Bhalla K. Flavopiridol down-regulates antiapoptotic proteins and sensitizes human breast cancer cells to epothilone B-induced apoptosis. Cancer Research. 63: 93-9. PMID 12517783 |
0.365 |
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| 2002 |
Yamaguchi H, Wang HG. Bcl-XL protects BimEL-induced Bax conformational change and cytochrome C release independent of interacting with Bax or BimEL. The Journal of Biological Chemistry. 277: 41604-12. PMID 12198137 DOI: 10.1074/jbc.M207516200 |
0.337 |
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| 2002 |
Hirai I, Wang H. A role of the C-terminal region of human Rad9 (hRad9) in nuclear transport of the hRad9 checkpoint complex. Journal of Biological Chemistry. 277: 25722-25727. PMID 11994305 DOI: 10.1074/Jbc.M203079200 |
0.34 |
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| 2002 |
Yoshida K, Komatsu K, Wang H, Kufe D. c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage. Molecular and Cellular Biology. 22: 3292-3300. PMID 11971963 DOI: 10.1128/Mcb.22.10.3292-3300.2002 |
0.388 |
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| 2002 |
Guo F, Nimmanapalli R, Paranawithana S, Wittman S, Griffin D, Bali P, O'Bryan E, Fumero C, Wang HG, Bhalla K. Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative-(BMS 247550) and Apo-2L/TRAIL-induced apoptosis. Blood. 99: 3419-26. PMID 11964312 DOI: 10.1182/Blood.V99.9.3419 |
0.329 |
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| 2002 |
Yamaguchi H, Paranawithana SR, Lee MW, Huang Z, Bhalla KN, Wang HG. Epothilone B analogue (BMS-247550)-mediated cytotoxicity through induction of Bax conformational change in human breast cancer cells. Cancer Research. 62: 466-71. PMID 11809697 |
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| 2001 |
Hirai I, Wang H. Survival-factor-induced phosphorylation of Bad results in its dissociation from Bcl-xL but not Bcl-2 Biochemical Journal. 359: 345-352. DOI: 10.1042/Bj3590345 |
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| 2000 |
Komatsu K, Wharton W, Hang H, Wu C, Singh S, Lieberman HB, Pledger WJ, Wang HG. PCNA interacts with hHus1/hRad9 in response to DNA damage and replication inhibition. Oncogene. 19: 5291-7. PMID 11077446 DOI: 10.1038/Sj.Onc.1203901 |
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| 2000 |
Komatsu K, Hopkins KM, Lieberman HB, Wang H. Schizosaccharomyces pombe Rad9 contains a BH3-like region and interacts with the anti-apoptotic protein Bcl-2. Febs Letters. 481: 122-6. PMID 10996309 DOI: 10.1016/S0014-5793(00)01975-X |
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| 2000 |
Neshat MS, Raitano AB, Wang HG, Reed JC, Sawyers CL. The survival function of the Bcr-Abl oncogene is mediated by Bad-dependent and -independent pathways: roles for phosphatidylinositol 3-kinase and Raf. Molecular and Cellular Biology. 20: 1179-86. PMID 10648603 DOI: 10.1128/Mcb.20.4.1179-1186.2000 |
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| 2000 |
Komatsu K, Miyashita T, Hang H, Hopkins KM, Zheng W, Cuddeback S, Yamada M, Lieberman HB, Wang HG. Human homologue of S. pombe Rad9 interacts with BCL-2/BCL-xL and promotes apoptosis. Nature Cell Biology. 2: 1-6. PMID 10620799 DOI: 10.1038/71316 |
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| 1999 |
Wang HG, Pathan N, Ethell IM, Krajewski S, Yamaguchi Y, Shibasaki F, McKeon F, Bobo T, Franke TF, Reed JC. Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD. Science (New York, N.Y.). 284: 339-43. PMID 10195903 DOI: 10.1126/Science.284.5412.339 |
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| 1999 |
Slee EA, Harte MT, Kluck RM, Wolf BB, Casiano CA, Newmeyer DD, Wang HG, Reed JC, Nicholson DW, Alnemri ES, Green DR, Martin SJ. Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner. The Journal of Cell Biology. 144: 281-92. PMID 9922454 DOI: 10.1083/Jcb.144.2.281 |
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| 1998 |
Wang H, Reed JC. Bcl-2, Raf-1 and mitochondrial regulation of apoptosis Biofactors. 8: 13-16. PMID 9699002 DOI: 10.1002/Biof.5520080103 |
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| 1998 |
Wang H, Reed JC. Mechanisms of Bcl-2 protein function Histology and Histopathology. 13: 521-530. PMID 9589906 DOI: 10.14670/Hh-13.521 |
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| 1998 |
Zapata JM, Krajewska M, Krajewski S, Huang R, Takayama S, Wang H, Adamson E, Reed JC. Expression of multiple apoptosis-regulatory genes in human breast cancer cell lines and primary tumors Breast Cancer Research and Treatment. 47: 129-140. PMID 9497101 DOI: 10.1023/A:1005940832123 |
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| 1998 |
Kitada S, Andersen J, Akar S, Zapata JM, Takayama S, Krajewski S, Wang H, Zhang X, Bullrich F, Croce CM, Rai K, Hines J, Reed JC. Expression of Apoptosis-Regulating Proteins in Chronic Lymphocytic Leukemia: Correlations With In Vitro and In Vivo Chemoresponses Blood. 91: 3379-3389. DOI: 10.1182/Blood.V91.9.3379.3379_3379_3389 |
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| 1997 |
Perry DK, Smyth MJ, Wang HG, Reed JC, Duriez P, Poirier GG, Obeid LM, Hannun YA. Bcl-2 acts upstream of the PARP protease and prevents its activation. Cell Death and Differentiation. 4: 29-33. PMID 16465207 DOI: 10.1038/Sj.Cdd.4400200 |
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| 1997 |
Susin SA, Zamzami N, Castedo M, Daugas E, Wang HG, Geley S, Fassy F, Reed JC, Kroemer G. The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis. The Journal of Experimental Medicine. 186: 25-37. PMID 9206994 DOI: 10.1084/Jem.186.1.25 |
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| 1997 |
Keane RW, Srinivasan A, Foster LM, Testa MP, Ord T, Nonner D, Wang HG, Reed JC, Bredesen DE, Kayalar C. Activation of CPP32 during apoptosis of neurons and astrocytes. Journal of Neuroscience Research. 48: 168-80. PMID 9130145 DOI: 10.1002/(Sici)1097-4547(19970415)48:2<168::Aid-Jnr9>3.0.Co;2-A |
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| 1997 |
Krajewski S, Gascoyne RD, Zapata JM, Krajewska M, Kitada S, Chhanabhai M, Horsman D, Berean K, Piro LD, Fugier-Vivier I, Liu Y, Wang H, Reed JC. Immunolocalization of the ICE/Ced-3 - Family Protease, CPP32 (Caspase-3), in Non-Hodgkin's Lymphomas, Chronic Lymphocytic Leukemias, and Reactive Lymph Nodes Blood. 89: 3817-3825. DOI: 10.1182/Blood.V89.10.3817.3817_3817_3825 |
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| 1996 |
Reed JC, Miyashita T, Takayama S, Wang H, Sato T, Krajewski S, Aimé-Sempé C, Bodrug S, Kitada S, Hanada M. BCL-2 family proteins: regulators of cell death involved in the pathogenesis of cancer and resistance to therapy. Journal of Cellular Biochemistry. 60: 23-32. PMID 8825412 DOI: 10.1002/(Sici)1097-4644(19960101)60:1<23::Aid-Jcb5>3.0.Co;2-5 |
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| 1996 |
Reed JC, Miyashita T, Krajewski S, Takayama S, Aime-Sempe C, Kitada S, Sato T, Wang H, Harigai M, Hanada M, Krajewska M, Kochel K, Millan J, Kobayashi H. Bcl-2 family proteins and the regulation of programmed cell death in leukemia and lymphoma. Cancer Treatment and Research. 84: 31-72. PMID 8724625 DOI: 10.1007/978-1-4613-1261-1_3 |
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| 1996 |
Wang H, Takayama S, Rapp UR, Reed JC. Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1 Proceedings of the National Academy of Sciences of the United States of America. 93: 7063-7068. PMID 8692945 DOI: 10.1073/Pnas.93.14.7063 |
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| 1996 |
Liu Y, Lee MO, Wang HG, Li Y, Hashimoto Y, Klaus M, Reed JC, Zhang X. Retinoic acid receptor beta mediates the growth-inhibitory effect of retinoic acid by promoting apoptosis in human breast cancer cells. Molecular and Cellular Biology. 16: 1138-49. PMID 8622658 DOI: 10.1128/Mcb.16.3.1138 |
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| 1995 |
Wang HG, Millan JA, Cox AD, Der CJ, Rapp UR, Beck T, Zha H, Reed JC. R-Ras promotes apoptosis caused by growth factor deprivation via a Bcl-2 suppressible mechanism. The Journal of Cell Biology. 129: 1103-14. PMID 7744959 DOI: 10.1083/Jcb.129.4.1103 |
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