| Year |
Citation |
Score |
| 2021 |
Keshari RS, Popescu NI, Silasi R, Regmi G, Lupu C, Simmons JH, Ricardo A, Coggeshall KM, Lupu F. Complement C5 inhibition protects against hemolytic anemia and acute kidney injury in anthrax peptidoglycan-induced sepsis in baboons. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34507997 DOI: 10.1073/pnas.2104347118 |
0.726 |
|
| 2021 |
Popescu NI, Lupu C, Lupu F. Disseminated intravascular coagulation and its immune mechanisms. Blood. PMID 34428280 DOI: 10.1182/blood.2020007208 |
0.719 |
|
| 2021 |
Puy C, Pang J, Reitsma SE, Lorentz CU, Tucker EI, Gailani D, Gruber A, Lupu F, McCarty OJT. Cross-Talk between the Complement Pathway and the Contact Activation System of Coagulation: Activated Factor XI Neutralizes Complement Factor H. Journal of Immunology (Baltimore, Md. : 1950). 206: 1784-1792. PMID 33811105 DOI: 10.4049/jimmunol.2000398 |
0.302 |
|
| 2020 |
Keshari RS, Silasi R, Popescu NI, Regmi G, Chaaban H, Lambris JD, Lupu C, Mollnes TE, Lupu F. CD14 inhibition improves survival and attenuates thrombo-inflammation and cardiopulmonary dysfunction in a baboon model of Escherichia coli sepsis. Journal of Thrombosis and Haemostasis : Jth. PMID 33174372 DOI: 10.1111/jth.15162 |
0.69 |
|
| 2020 |
Lupu F, Kinasewitz G, Dormer K. The role of endothelial shear stress on haemodynamics, inflammation, coagulation and glycocalyx during sepsis. Journal of Cellular and Molecular Medicine. PMID 32951280 DOI: 10.1111/Jcmm.15895 |
0.38 |
|
| 2020 |
Popescu NI, Keshari RS, Cochran J, Coggeshall KM, Lupu F. C3 Opsonization of Anthrax Bacterium and Peptidoglycan Supports Recognition and Activation of Neutrophils. Microorganisms. 8. PMID 32668703 DOI: 10.3390/microorganisms8071039 |
0.695 |
|
| 2020 |
Chaaban H, Burge K, Eckert J, Keshari RS, Silasi R, Lupu C, Warner B, Escobedo M, Caplan M, Lupu F. Neutrophil extracellular trap inhibition increases inflammation, bacteraemia and mortality in murine necrotizing enterocolitis. Journal of Cellular and Molecular Medicine. PMID 32515131 DOI: 10.1111/Jcmm.15338 |
0.378 |
|
| 2019 |
Keshari RS, Silasi R, Popescu NI, Georgescu C, Chaaban H, Lupu C, McCarty OJT, Esmon CT, Lupu F. Fondaparinux pentasaccharide reduces sepsis coagulopathy and promotes survival in the baboon model of E. coli sepsis. Journal of Thrombosis and Haemostasis : Jth. PMID 31549765 DOI: 10.1111/Jth.14642 |
0.707 |
|
| 2019 |
Puy C, Ngo ATP, Pang J, Keshari RS, Hagen MW, Hinds MT, Gailani D, Gruber A, Lupu F, McCarty OJT. Endothelial PAI-1 (Plasminogen Activator Inhibitor-1) Blocks the Intrinsic Pathway of Coagulation, Inducing the Clearance and Degradation of FXIa (Activated Factor XI). Arteriosclerosis, Thrombosis, and Vascular Biology. 39: 1390-1401. PMID 31242030 DOI: 10.1161/Atvbaha.119.312619 |
0.422 |
|
| 2019 |
Silasi R, Keshari RS, Lupu C, Van Rensburg WJ, Chaaban H, Regmi G, Shamanaev A, Shatzel JJ, Puy C, Lorentz CU, Tucker EI, Gailani D, Gruber A, McCarty OJT, Lupu F. Inhibition of contact-mediated activation of factor XI protects baboons against -induced organ damage and death. Blood Advances. 3: 658-669. PMID 30808684 DOI: 10.1182/Bloodadvances.2018029983 |
0.446 |
|
| 2018 |
Zilberman-Rudenko J, Reitsma SE, Puy C, Rigg RA, Smith SA, Tucker EI, Silasi R, Merkulova A, McCrae KR, Maas C, Urbanus RT, Gailani D, Morrissey JH, Gruber A, Lupu F, et al. Factor XII Activation Promotes Platelet Consumption in the Presence of Bacterial-Type Long-Chain Polyphosphate In Vitro and In Vivo. Arteriosclerosis, Thrombosis, and Vascular Biology. 38: 1748-1760. PMID 30354195 DOI: 10.1161/Atvbaha.118.311193 |
0.367 |
|
| 2018 |
Popescu NI, Silasi R, Keshari RS, Girton A, Burgett T, Zeerleder SS, Gailani D, Gruber A, Lupu F, Coggeshall KM. Peptidoglycan induces disseminated intravascular coagulation in baboons through activation of both coagulation pathways. Blood. PMID 29921614 DOI: 10.1182/Blood-2017-10-813618 |
0.758 |
|
| 2018 |
Girton AW, Popescu NI, Keshari RS, Burgett T, Lupu F, Coggeshall KM. Serum amyloid P and IgG exhibit differential capabilities in the activation of the innate immune system in response topeptidoglycan. Infection and Immunity. PMID 29531132 DOI: 10.1128/Iai.00076-18 |
0.715 |
|
| 2017 |
Keshari RS, Silasi R, Lupu C, Taylor FB, Lupu F. In vivo generated thrombin and plasmin do not activate the complement system in baboons. Blood. PMID 29021229 DOI: 10.1182/Blood-2017-06-788216 |
0.401 |
|
| 2017 |
Song K, Fu J, Song J, Herzog BH, Bergstrom K, Kondo Y, McDaniel JM, McGee S, Silasi-Mansat R, Lupu F, Chen H, Bagavant H, Xia L. Loss of mucin-type O-glycans impairs the integrity of the glomerular filtration barrier in the mouse kidney. The Journal of Biological Chemistry. PMID 28842487 DOI: 10.1074/Jbc.M117.798512 |
0.303 |
|
| 2017 |
Menendez MT, Ong EC, Shepherd BT, Muthukumar V, Silasi-Mansat R, Lupu F, Griffin CT. BRG1 (Brahma-Related Gene 1) Promotes Endothelial Mrtf Transcription to Establish Embryonic Capillary Integrity. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 28729363 DOI: 10.1161/Atvbaha.117.309785 |
0.318 |
|
| 2017 |
Keshari RS, Silasi R, Popescu NI, Patel MM, Chaaban H, Lupu C, Coggeshall KM, Mollnes TE, DeMarco SJ, Lupu F. Inhibition of complement C5 protects against organ failure and reduces mortality in a baboon model of Escherichia coli sepsis. Proceedings of the National Academy of Sciences of the United States of America. PMID 28720697 DOI: 10.1073/Pnas.1706818114 |
0.737 |
|
| 2017 |
Healy LD, Puy C, Fernández JA, Mitrugno A, Keshari RS, Taku NA, Chu TT, Xu X, Gruber A, Lupu F, Griffin JH, McCarty OJ. Activated protein C inhibits neutrophil extracellular trap formation in vitro and activation in vivo. The Journal of Biological Chemistry. PMID 28408624 DOI: 10.1074/Jbc.M116.768309 |
0.452 |
|
| 2016 |
Frej C, Linder A, Happonen KE, Taylor FB, Lupu F, Dahlbäck B. Sphingosine 1-phosphate and its carrier apolipoprotein M in human sepsis and in Escherichia coli sepsis in baboons. Journal of Cellular and Molecular Medicine. PMID 26990127 DOI: 10.1111/Jcmm.12831 |
0.318 |
|
| 2016 |
Keshari RS, Silasi-Mansat R, Lupu C, Taylor FB, Lupu F. Bacteremia, Not Coagulation Proteases Contribute to In Vivo Complement Activation in Sepsis Blood. 128: 275-275. DOI: 10.1182/Blood.V128.22.275.275 |
0.409 |
|
| 2015 |
Geng X, Cha B, Mahamud MR, Lim KC, Silasi-Mansat R, Uddin MK, Miura N, Xia L, Simon AM, Douglas Engel J, Chen H, Lupu F, Sathish Srinivasan R. Multiple Mouse Models of Primary Lymphedema Exhibit Distinct Defects in Lymphovenous Valve Development. Developmental Biology. PMID 26542011 DOI: 10.1016/J.Ydbio.2015.10.022 |
0.325 |
|
| 2015 |
Silasi-Mansat R, Zhu H, Georgescu C, Popescu N, Keshari RS, Peer G, Lupu C, Taylor FB, Pereira HA, Kinasewitz G, Lambris JD, Lupu F. Complement inhibition decreases early fibrogenic events in the lung of septic baboons. Journal of Cellular and Molecular Medicine. PMID 26337158 DOI: 10.1111/Jcmm.12667 |
0.749 |
|
| 2015 |
Chaaban H, Keshari RS, Silasi-Mansat R, Popescu NI, Mehta-D'Souza P, Lim YP, Lupu F. Inter-α inhibitor protein and its associated glycosaminoglycans protect against histone-induced injury. Blood. 125: 2286-96. PMID 25631771 DOI: 10.1182/Blood-2014-06-582759 |
0.717 |
|
| 2015 |
Jackson KW, Christiansen VJ, Yadav VR, Silasi-Mansat R, Lupu F, Awasthi V, Zhang RR, McKee PA. Suppression of tumor growth in mice by rationally designed pseudopeptide inhibitors of fibroblast activation protein and prolyl oligopeptidase. Neoplasia (New York, N.Y.). 17: 43-54. PMID 25622898 DOI: 10.1016/J.Neo.2014.11.002 |
0.322 |
|
| 2015 |
Keshari RS, Silasi-Mansat R, Popescu NI, Langer M, Chaaban H, Lupu C, Coggeshall MK, DeMarco S, Lupu F. Complement C5 Inhibition Blocks the Cytokine Storm and Consumptive Coagulopathy By Decreasing Lipopolysaccharide (LPS) Release in E. coli Sepsis Blood. 126: 765-765. DOI: 10.1182/Blood.V126.23.765.765 |
0.74 |
|
| 2014 |
Lupu F, Keshari RS, Lambris JD, Coggeshall KM. Crosstalk between the coagulation and complement systems in sepsis. Thrombosis Research. 133: S28-31. PMID 24759136 DOI: 10.1016/J.Thromres.2014.03.014 |
0.409 |
|
| 2014 |
Risitano AM, Ricklin D, Huang Y, Reis ES, Chen H, Ricci P, Lin Z, Pascariello C, Raia M, Sica M, Del Vecchio L, Pane F, Lupu F, Notaro R, Resuello RR, et al. Peptide inhibitors of C3 activation as a novel strategy of complement inhibition for the treatment of paroxysmal nocturnal hemoglobinuria. Blood. 123: 2094-101. PMID 24497537 DOI: 10.1182/Blood-2013-11-536573 |
0.325 |
|
| 2014 |
Keshari RS, Silasi-Mansat R, Zhu H, Popescu NI, Peer G, Chaaban H, Lambris JD, Polf H, Lupu C, Kinasewitz G, Lupu F. Acute lung injury and fibrosis in a baboon model of Escherichia coli sepsis. American Journal of Respiratory Cell and Molecular Biology. 50: 439-50. PMID 24066737 DOI: 10.1165/Rcmb.2013-0219Oc |
0.735 |
|
| 2014 |
Keshari R, Silasi-Mansat R, Popescu NI, Chaaban H, Lupu C, DeMarco SJ, Lupu F. A Novel C5 Complement Inhibitor Protects Against Sepsis-Induced Activation of Complement, Coagulation and Inflammation and Provides Survival Benefit in E. coli Sepsis Blood. 124: 112-112. DOI: 10.1182/Blood.V124.21.112.112 |
0.737 |
|
| 2013 |
Ingram KG, Curtis CD, Silasi-Mansat R, Lupu F, Griffin CT. The NuRD chromatin-remodeling enzyme CHD4 promotes embryonic vascular integrity by transcriptionally regulating extracellular matrix proteolysis. Plos Genetics. 9: e1004031. PMID 24348274 DOI: 10.1371/Journal.Pgen.1004031 |
0.371 |
|
| 2013 |
Yao L, Yago T, Shao B, Liu Z, Silasi-Mansat R, Setiadi H, Lupu F, McEver RP. Elevated CXCL1 expression in gp130-deficient endothelial cells impairs neutrophil migration in mice. Blood. 122: 3832-42. PMID 24081661 DOI: 10.1182/Blood-2012-12-473835 |
0.365 |
|
| 2013 |
Herzog BH, Fu J, Wilson SJ, Hess PR, Sen A, McDaniel JM, Pan Y, Sheng M, Yago T, Silasi-Mansat R, McGee S, May F, Nieswandt B, Morris AJ, Lupu F, et al. Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2. Nature. 502: 105-9. PMID 23995678 DOI: 10.1038/Nature12501 |
0.356 |
|
| 2013 |
Coggeshall KM, Lupu F, Ballard J, Metcalf JP, James JA, Farris D, Kurosawa S. The sepsis model: an emerging hypothesis for the lethality of inhalation anthrax. Journal of Cellular and Molecular Medicine. 17: 914-20. PMID 23742651 DOI: 10.1111/Jcmm.12075 |
0.302 |
|
| 2013 |
Sun D, Popescu NI, Raisley B, Keshari RS, Dale GL, Lupu F, Coggeshall KM. Bacillus anthracis peptidoglycan activates human platelets through FcγRII and complement. Blood. 122: 571-9. PMID 23733338 DOI: 10.1182/Blood-2013-02-486613 |
0.735 |
|
| 2013 |
Chaaban H, Keshari R, Mehta-D'Souza P, Silasi-Mansat R, Popescu NI, Lupu F. Protective Mechanisms Of Inter-Alpha Inhibitor Protein On Extracellular Histone Toxicity Blood. 122: 19-19. DOI: 10.1182/Blood.V122.21.19.19 |
0.713 |
|
| 2012 |
Pasula S, Cai X, Dong Y, Messa M, McManus J, Chang B, Liu X, Zhu H, Mansat RS, Yoon SJ, Hahn S, Keeling J, Saunders D, Ko G, Knight J, ... ... Lupu F, et al. Endothelial epsin deficiency decreases tumor growth by enhancing VEGF signaling. The Journal of Clinical Investigation. 122: 4424-38. PMID 23187125 DOI: 10.1172/Jci64537 |
0.308 |
|
| 2012 |
Langer M, Duggan ES, Booth JL, Patel VI, Zander RA, Silasi-Mansat R, Ramani V, Veres TZ, Prenzler F, Sewald K, Williams DM, Coggeshall KM, Awasthi S, Lupu F, Burian D, et al. Bacillus anthracis lethal toxin reduces human alveolar epithelial barrier function. Infection and Immunity. 80: 4374-87. PMID 23027535 DOI: 10.1128/Iai.01011-12 |
0.361 |
|
| 2012 |
Zhai Z, Gomez-Mejiba SE, Zhu H, Lupu F, Ramirez DC. The spin trap 5,5-dimethyl-1-pyrroline N-oxide inhibits lipopolysaccharide-induced inflammatory response in RAW 264.7 cells. Life Sciences. 90: 432-9. PMID 22285597 DOI: 10.1016/J.Lfs.2011.12.018 |
0.313 |
|
| 2012 |
Taylor FB, Kinasewitz GT, Lupu F. Pathophysiology, staging and therapy of severe sepsis in baboon models Journal of Cellular and Molecular Medicine. 16: 672-682. PMID 21972970 DOI: 10.1111/J.1582-4934.2011.01454.X |
0.36 |
|
| 2012 |
Popescu NI, Merrill JT, Lupu F. Inhibitory Autoantibodies to Protein Disulfide Isomerase From Systemic Lupus Erythematosus Patients Are Prothrombotic Blood. 120: 392-392. DOI: 10.1182/Blood.V120.21.392.392 |
0.724 |
|
| 2012 |
Towner RA, Jensen RL, Smith N, Casteel R, Saunders D, Gillespie DL, Silasi-Mansat R, Lupu F, Giles CB, Wren JD. Abstract 2986: A novel biomarker for gliomas, ELTD1 Cancer Research. 72: 2986-2986. DOI: 10.1158/1538-7445.Am2012-2986 |
0.304 |
|
| 2011 |
Lupu C, Zhu H, Popescu NI, Wren JD, Lupu F. Novel protein ADTRP regulates TFPI expression and function in human endothelial cells in normal conditions and in response to androgen. Blood. 118: 4463-71. PMID 21868574 DOI: 10.1182/blood-2011-05-355370 |
0.726 |
|
| 2011 |
Esmon CT, Xu J, Lupu F. Innate immunity and coagulation Journal of Thrombosis and Haemostasis. 9: 182-188. PMID 21781254 DOI: 10.1111/J.1538-7836.2011.04323.X |
0.405 |
|
| 2011 |
Zhang X, Yu H, Lou JR, Zheng J, Zhu H, Popescu NI, Lupu F, Lind SE, Ding WQ. MicroRNA-19 (miR-19) regulates tissue factor expression in breast cancer cells. The Journal of Biological Chemistry. 286: 1429-35. PMID 21059650 DOI: 10.1074/Jbc.M110.146530 |
0.698 |
|
| 2011 |
He T, Smith N, Saunders D, Doblas S, Watanabe Y, Hoyle J, Silasi-Mansat R, Lupu F, Lerner M, Brackett DJ, Towner RA. Molecular MRI assessment of vascular endothelial growth factor receptor-2 in rat C6 gliomas. Journal of Cellular and Molecular Medicine. 15: 837-49. PMID 20497492 DOI: 10.1111/J.1582-4934.2010.01091.X |
0.323 |
|
| 2011 |
Lupu F, Zhu H, Silasi-Mansat R, Georgescu C, Popescu N, Peer G, Lupu C, Taylor F, Kinasewitz G, Lambris J. Sepsis-induced lung fibrosis in baboons is reduced by the treatment with a complement inhibitor Critical Care. 15: 34. DOI: 10.1186/Cc10403 |
0.711 |
|
| 2010 |
Silasi-Mansat R, Zhu H, Popescu NI, Peer G, Sfyroera G, Magotti P, Ivanciu L, Lupu C, Mollnes TE, Taylor FB, Kinasewitz G, Lambris JD, Lupu F. Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of Escherichia coli sepsis Blood. 116: 1002-1010. PMID 20466856 DOI: 10.1182/Blood-2010-02-269746 |
0.752 |
|
| 2010 |
Popescu NI, Lupu C, Lupu F. Extracellular protein disulfide isomerase regulates coagulation on endothelial cells through modulation of phosphatidylserine exposure. Blood. 116: 993-1001. PMID 20448108 DOI: 10.1182/Blood-2009-10-249607 |
0.745 |
|
| 2010 |
Popescu NI, Lupu C, Lupu F. Role of PDI in regulating tissue factor: FVIIa activity. Thrombosis Research. 125: S38-41. PMID 20163832 DOI: 10.1016/J.Thromres.2010.01.034 |
0.73 |
|
| 2010 |
Towner RA, Smith N, Doblas S, Garteiser P, Watanabe Y, He T, Saunders D, Herlea O, Silasi-Mansat R, Lupu F. In vivo detection of inducible nitric oxide synthase in rodent gliomas. Free Radical Biology & Medicine. 48: 691-703. PMID 20034558 DOI: 10.1016/J.Freeradbiomed.2009.12.012 |
0.316 |
|
| 2010 |
Xu J, Lupu F, Esmon CT. Crosstalk Between Inflammation and Thrombosis: The Surprising Role of Extracellular Histones Blood. 116. DOI: 10.1182/Blood.V116.21.Mrg-1.Mrg-1 |
0.359 |
|
| 2010 |
Lupu C, Zhu H, Wren J, Lupu F. Novel Protein Encoded by C6orf105 Regulates Tissue Factor Pathway Inhibitor Expression and Function In Human Endothelial Cells In Normal Conditions and During Androgen Stimulation Blood. 116: 348-348. DOI: 10.1182/Blood.V116.21.348.348 |
0.431 |
|
| 2010 |
Popescu NI, Lupu C, Lupu F. Calcium Ionophore-Induced Tissue Factor (TF) Decryption Induces TF Immobilization Into Lipid Rafts and Negative Regulation of TF Procoagulant Activity. Blood. 116: 1131-1131. DOI: 10.1182/Blood.V116.21.1131.1131 |
0.722 |
|
| 2010 |
Zhang X, Yu H, Lou JR, Zheng J, Popescu N, Lupu F, Ding W. Abstract 2048: microRNA regulation of tissue factor expression in breast cancer cells Cancer Research. 70: 2048-2048. DOI: 10.1158/1538-7445.Am10-2048 |
0.308 |
|
| 2010 |
Lupu F, Silasi-Mansat R, Zhu H, Popescu NI, Peer G, Sfyroera G, Magotti P, Ivanciu L, Lupu C, Mollnes TE. Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of E. coli sepsis Molecular Immunology. 47: 2289-2289. DOI: 10.1016/J.Molimm.2010.05.269 |
0.713 |
|
| 2009 |
Xu J, Zhang X, Pelayo R, Monestier M, Ammollo CT, Semeraro F, Taylor FB, Esmon NL, Lupu F, Esmon CT. Extracellular histones are major mediators of death in sepsis. Nature Medicine. 15: 1318-21. PMID 19855397 DOI: 10.1038/Nm.2053 |
0.355 |
|
| 2008 |
Lelièvre E, Hinek A, Lupu F, Buquet C, Soncin F, Mattot V. VE-statin/egfl7 regulates vascular elastogenesis by interacting with lysyl oxidases. The Embo Journal. 27: 1658-70. PMID 18497746 DOI: 10.1038/Emboj.2008.103 |
0.351 |
|
| 2008 |
Lupu F. "Crossroads in Sepsis Research" Review Series Overview of the pathophysiology of sepsis. Journal of Cellular and Molecular Medicine. 12: 1072-3. PMID 18485107 DOI: 10.1111/J.1582-4934.2008.00366.X |
0.347 |
|
| 2008 |
Towner RA, Smith N, Doblas S, Tesiram Y, Garteiser P, Saunders D, Cranford R, Silasi-Mansat R, Herlea O, Ivanciu L, Wu D, Lupu F. In vivo detection of c-Met expression in a rat C6 glioma model Journal of Cellular and Molecular Medicine. 12: 174-186. PMID 18194445 DOI: 10.1111/J.1582-4934.2008.00220.X |
0.303 |
|
| 2008 |
Tjwa M, Bellido-Martin L, Lin Y, Lutgens E, Plaisance S, Bono F, Delesque-Touchard N, Hervé C, Moura R, Billiau AD, Aparicio C, Levi M, Daemen M, Dewerchin M, Lupu F, et al. Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes. Blood. 111: 4096-105. PMID 18156494 DOI: 10.1182/Blood-2007-05-089565 |
0.406 |
|
| 2007 |
Tang H, Ivanciu L, Popescu N, Peer G, Hack E, Lupu C, Taylor FB, Lupu F. Sepsis-induced coagulation in the baboon lung is associated with decreased tissue factor pathway inhibitor American Journal of Pathology. 171: 1066-1077. PMID 17640967 DOI: 10.2353/Ajpath.2007.070104 |
0.748 |
|
| 2007 |
Zhu H, Tang Y, Ivanciu L, Centola M, Lupu C, Taylor FB, Lupu F. Temporal dynamics of gene expression in the lung in a baboon model of E. coli sepsis. Bmc Genomics. 8: 58. PMID 17324256 DOI: 10.1186/1471-2164-8-58 |
0.304 |
|
| 2007 |
Zwerts F, Lupu F, De Vriese A, Pollefeyt S, Moons L, Altura RA, Jiang Y, Maxwell PH, Hill P, Oh H, Rieker C, Collen D, Conway SJ, Conway EM. Lack of endothelial cell survivin causes embryonic defects in angiogenesis, cardiogenesis, and neural tube closure Blood. 109: 4742-4752. PMID 17299096 DOI: 10.1182/Blood-2006-06-028068 |
0.343 |
|
| 2007 |
Ivanciu L, Gerard RD, Tang H, Lupu F, Lupu C. Adenovirus-mediated expression of tissue factor pathway inhibitor-2 inhibits endothelial cell migration and angiogenesis Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 310-316. PMID 17138934 DOI: 10.1161/01.Atv.0000254147.89321.Cf |
0.348 |
|
| 2007 |
Orlova V, Economopoulou M, Lupu F, Santoso S, Chavakis T. Junctional Adhesion Molecule (JAM)-C Regulates Endothelial Permeability by Modulating VE-Cadherin-Mediated Interendothelial Contacts The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A187-B |
0.304 |
|
| 2006 |
Orlova VV, Economopoulou M, Lupu F, Santoso S, Chavakis T. Junctional adhesion molecule-C regulates vascular endothelial permeability by modulating VE-cadherin-mediated cell-cell contacts. The Journal of Experimental Medicine. 203: 2703-14. PMID 17116731 DOI: 10.1084/Jem.20051730 |
0.351 |
|
| 2006 |
Taylor FB, Hack E, Lupu F. Observations on complement activity in the two-stage inflammatory/hemostatic response in the baboon and human models of E. coli sepsis and endotoxemia Advances in Experimental Medicine and Biology. 586: 203-216. PMID 16893074 DOI: 10.1007/0-387-34134-X_14 |
0.33 |
|
| 2006 |
Stearns-Kurosawa DJ, Lupu F, Taylor FB, Kinasewitz G, Kurosawa S. Sepsis and pathophysiology of anthrax in a nonhuman primate model American Journal of Pathology. 169: 433-444. PMID 16877346 DOI: 10.2353/Ajpath.2006.051330 |
0.34 |
|
| 2006 |
Rossignol P, Luttun A, Martin-Ventura JL, Lupu F, Carmeliet P, Collen D, Anglès-Cano E, Lijnen HR. Plasminogen activation: a mediator of vascular smooth muscle cell apoptosis in atherosclerotic plaques Journal of Thrombosis and Haemostasis. 4: 664-670. PMID 16460449 DOI: 10.1111/J.1538-7836.2005.01765.X |
0.361 |
|
| 2006 |
Ivanciu L, Lupu C, Lupu F. Caveolin-1 Deficiency in Mice Leads to Increased Protection Against Endotoxemia. Blood. 108: 1814-1814. DOI: 10.1182/Blood.V108.11.1814.1814 |
0.329 |
|
| 2006 |
Lupu C, Lupu F. Functional Regulation of TFPI in Membrane Lipid Rafts. Blood. 108: 1753-1753. DOI: 10.1182/Blood.V108.11.1753.1753 |
0.375 |
|
| 2006 |
Herlea O, Taylor F, Lupu F. Id: 210 Organ-Specific Expression Of The Plasminogen Activating System In A Baboon Model Of Sepsis Journal of Thrombosis and Haemostasis. 4: 116-116. DOI: 10.1111/J.1538-7836.2006.00210.X |
0.327 |
|
| 2005 |
Ny A, Koch M, Schneider M, Neven E, Tong RT, Maity S, Fischer C, Plaisance S, Lambrechts D, Héligon C, Terclavers S, Ciesiolka M, Kälin R, Man WY, Senn I, ... ... Lupu F, et al. A genetic Xenopus laevis tadpole model to study lymphangiogenesis. Nature Medicine. 11: 998-1004. PMID 16116431 DOI: 10.1038/Nm1285 |
0.322 |
|
| 2005 |
Li W, Zheng X, Gu J, Hunter J, Ferrell GL, Lupu F, Esmon NL, Esmon CT. Overexpressing endothelial cell protein C receptor alters the hemostatic balance and protects mice from endotoxin Journal of Thrombosis and Haemostasis. 3: 1351-1359. PMID 15978090 DOI: 10.1111/J.1538-7836.2005.01385.X |
0.376 |
|
| 2005 |
Lupu C, Hu X, Lupu F. Caveolin-1 enhances tissue factor pathway inhibitor exposure and function on the cell surface. The Journal of Biological Chemistry. 280: 22308-17. PMID 15817451 DOI: 10.1074/Jbc.M503333200 |
0.409 |
|
| 2005 |
Ivanciu L, Herlea O, Zhu H, Taylor FB, Lupu C, Lupu F. Tissue Characterization of Hypoxia, Nitric Oxide and Apoptosis Pathways in a Baboon Model of E. coli Sepsis. Blood. 106: 138-138. DOI: 10.1182/Blood.V106.11.138.138 |
0.424 |
|
| 2004 |
Tang H, Ivanciu L, Hamm T, Taylor FB, Lupu C, Lupu F. Sepsis-Induced Coagulation in the Baboon Lung Is Associated with Decreased Endothelial Tissue Factor Pathway Inhibitor. Blood. 104: 803-803. DOI: 10.1182/Blood.V104.11.803.803 |
0.477 |
|
| 2003 |
Collen A, Hanemaaijer R, Lupu F, Quax PH, van Lent N, Grimbergen J, Peters E, Koolwijk P, van Hinsbergh VW. Membrane-type matrix metalloproteinase-mediated angiogenesis in a fibrin-collagen matrix. Blood. 101: 1810-7. PMID 12393408 DOI: 10.1182/Blood-2002-05-1593 |
0.302 |
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| 2002 |
Compernolle V, Brusselmans K, Acker T, Hoet P, Tjwa M, Beck H, Plaisance S, Dor Y, Keshet E, Lupu F, Nemery B, Dewerchin M, Van Veldhoven P, Plate K, Moons L, et al. Loss of HIF-2alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice. Nature Medicine. 8: 702-10. PMID 12053176 DOI: 10.1038/Nm721 |
0.321 |
|
| 2002 |
Luttun A, Lupu F, Storkebaum E, Hoylaerts MF, Moons L, Crawley J, Bono F, Poole AR, Tipping P, Herbert JM, Collen D, Carmeliet P. Lack of plasminogen activator inhibitor-1 promotes growth and abnormal matrix remodeling of advanced atherosclerotic plaques in apolipoprotein E-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 499-505. PMID 11884297 DOI: 10.1161/Hq0302.104529 |
0.33 |
|
| 2002 |
Crawley JT, Goulding DA, Ferreira V, Severs NJ, Lupu F. Expression and localization of tissue factor pathway inhibitor-2 in normal and atherosclerotic human vessels. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 218-24. PMID 11834519 DOI: 10.1161/Hq0102.101842 |
0.394 |
|
| 2001 |
Angelillo-Scherrer A, Frutos PGd, Aparicio C, Melis E, Savi P, Lupu F, Arnout J, Dewerchin M, Hoylaerts MF, Herbert J, Collen D, Dahlbäck B, Carmeliet P. Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis. Nature Medicine. 7: 215-221. PMID 11175853 DOI: 10.1038/84667 |
0.339 |
|
| 2001 |
Collen A, Maas A, Kooistra T, Lupu F, Grimbergen J, Haas FJ, Biesma DH, Koolwijk P, Koopman J, van Hinsbergh VW. Aberrant fibrin formation and cross-linking of fibrinogen Nieuwegein, a variant with a shortened Aalpha-chain, alters endothelial capillary tube formation. Blood. 97: 973-80. PMID 11159525 DOI: 10.1182/Blood.V97.4.973 |
0.342 |
|
| 2001 |
Westmuckett AD, Kakkar VV, Hamuro T, Lupu F, Lupu C. Bemiparin and fluid flow modulate the expression, activity and release of tissue factor pathway inhibitor in human endothelial cells in vitro. Thrombosis and Haemostasis. 86: 1547-1554. DOI: 10.1055/S-0037-1616761 |
0.358 |
|
| 2001 |
Chavakis T, Willuweit AK, Lupu F, Preissner KT, Kanse SM. Release of soluble urokinase receptor from vascular cells. Thrombosis and Haemostasis. 86: 686-693. DOI: 10.1055/S-0037-1616105 |
0.353 |
|
| 2000 |
Chavakis T, Kanse SM, Lupu F, Hammes H, Müller-Esterl W, Pixley RA, Colman RW, Preissner KT. Different mechanisms define the antiadhesive function of high molecular weight kininogen in integrin- and urokinase receptor-dependent interactions. Blood. 96: 514-522. DOI: 10.1182/Blood.V96.2.514.014K45_514_522 |
0.322 |
|
| 2000 |
Westmuckett AD, Lupu C, Goulding DA, Das S, Kakkar VV, Lupu F. In situ analysis of tissue factor-dependent thrombin generation in human atherosclerotic vessels. Thrombosis and Haemostasis. 84: 904-911. DOI: 10.1055/S-0037-1614135 |
0.35 |
|
| 2000 |
Luttun A, Herbert J, Moons L, Tipping P, Collen D, Lupu F, Carmeliet P. Paradoxical increase of plaque growth and collagen deposition in atherosclerotic mice lacking plasminogen activator inhibitor-1 (PAI-1) Atherosclerosis. 151: 66-66. DOI: 10.1016/S0021-9150(00)80302-0 |
0.31 |
|
| 1999 |
Heymans S, Luttun A, Nuyens D, Theilmeier G, Creemers E, Moons L, Dyspersin GD, Cleutjens JP, Shipley M, Angellilo A, Levi M, Nübe O, Baker A, Keshet E, Lupu F, et al. Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure. Nature Medicine. 5: 1135-1142. PMID 10502816 DOI: 10.1038/13459 |
0.305 |
|
| 1999 |
Lupu C, Poulsen E, Roquefeuil S, Westmuckett AD, Kakkar VV, Lupu F. Cellular Effects of Heparin on the Production and Release of Tissue Factor Pathway Inhibitor in Human Endothelial Cells in Culture Arteriosclerosis, Thrombosis, and Vascular Biology. 19: 2251-2262. PMID 10479670 DOI: 10.1161/01.Atv.19.9.2251 |
0.409 |
|
| 1999 |
Carmeliet P, Lampugnani M, Moons L, Breviario F, Compernolle V, Bono F, Balconi G, Spagnuolo R, Oosthuyse B, Dewerchin M, Zanetti A, Angellilo A, Mattot V, Nuyens D, Lutgens E, ... ... Lupu F, et al. Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis. Cell. 98: 147-157. PMID 10428027 DOI: 10.1016/S0092-8674(00)81010-7 |
0.322 |
|
| 1999 |
Lupu C, Roquefeuil S, Westmuckett AD, Poulsen E, Kakkar VV, Lupu F. O3 Heparin modulates the expression and release of tissue factor pathway inhibitor in human endothelial cells in culture Blood Coagulation & Fibrinolysis. 10: 531. DOI: 10.1097/00001721-199912000-00015 |
0.326 |
|
| 1999 |
Lupu C, Kruithof EKO, Kakkar VV, Lupu F. Acute release of tissue factor pathway inhibitor after in vivo thrombin generation in baboons. Thrombosis and Haemostasis. 82: 1652-1658. DOI: 10.1055/S-0037-1614895 |
0.4 |
|
| 1997 |
Lupu C, Goodwin CA, Westmuckett AD, Emeis JJ, Scully MF, Kakkar VV, Lupu F. Tissue factor pathway inhibitor in endothelial cells colocalizes with glycolipid microdomains/caveolae. Regulatory mechanism(s) of the anticoagulant properties of the endothelium. Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 2964-74. PMID 9409283 DOI: 10.1161/01.Atv.17.11.2964 |
0.396 |
|
| 1997 |
Carmeliet P, Moons L, Lijnen R, Baes M, Lemaître V, Tipping P, Drew A, Eeckhout Y, Shapiro S, Lupu F, Collen D. Urokinase-generated plasmin activates matrix metalloproteinases during aneurysm formation Nature Genetics. 17: 439-444. PMID 9398846 DOI: 10.1038/Ng1297-439 |
0.321 |
|
| 1997 |
Emeis JJ, van den Eijnden-Schrauwen Y, van den Hoogen CM, de Priester W, Westmuckett A, Lupu F. An endothelial storage granule for tissue-type plasminogen activator. The Journal of Cell Biology. 139: 245-56. PMID 9314543 DOI: 10.1083/Jcb.139.1.245 |
0.328 |
|
| 1996 |
Lupu C, Lupu F, Kakkar VV, Scully MF. Tissue factor pathway inhibitor in human endothelial cells. Internal storage pool and agonist-induced acute release Blood Coagulation & Fibrinolysis. 7: 371. DOI: 10.1097/00001721-199604000-00021 |
0.356 |
|
| 1995 |
Benzakour O, Kanthou C, Lupu F, Dennehy U, Goodwin C, Scully MF, Kakkar VV, Cooper DN. Prothrombin cleavage by human vascular smooth muscle cells: A potential alternative pathway to the coagulation cascade Journal of Cellular Biochemistry. 59: 514-528. PMID 8749720 DOI: 10.1002/Jcb.240590411 |
0.324 |
|
| 1995 |
Lupu F, Heim DA, Bachmann F, Hurni M, Kakkar VV, Kruithof EKO. Plasminogen Activator Expression in Human Atherosclerotic Lesions Arteriosclerosis, Thrombosis, and Vascular Biology. 15: 1444-1455. PMID 7670960 DOI: 10.1161/01.Atv.15.9.1444 |
0.334 |
|
| 1995 |
Lupu C, Lupu F, Dennehy U, Kakkar VV, Scully MF. Thrombin Induces the Redistribution and Acute Release of Tissue Factor Pathway Inhibitor From Specific Granules Within Human Endothelial Cells in Culture Arteriosclerosis, Thrombosis, and Vascular Biology. 15: 2055-2062. PMID 7583589 DOI: 10.1161/01.Atv.15.11.2055 |
0.401 |
|
| 1995 |
Kanthou C, Benzakour O, Patel G, Deadman J, Kakkar VV, Lupu F. Thrombin receptor activating peptide (TRAP) stimulates mitogenesis, c-fos and PDGF-A gene expression in human vascular smooth muscle cells. Thrombosis and Haemostasis. 74: 1340-1347. DOI: 10.1055/S-0038-1649937 |
0.358 |
|
| 1994 |
Moldovan NI, Lupu F, Moldovan L, Simionescu N. 4-Hydroxynonenal induces membrane perturbations and inhibition of basal prostacyclin production in endothelial cells, and migration of monocytes. Cell Biology International. 18: 985-992. PMID 7881386 DOI: 10.1006/Cbir.1994.1020 |
0.333 |
|
| 1993 |
Lupu F, Bergonzelli GE, Heim DA, Cousin E, Genton CY, Bachmann F, Kruithof EKO. Localization and production of plasminogen activator inhibitor-1 in human healthy and atherosclerotic arteries. Arteriosclerosis, Thrombosis, and Vascular Biology. 13: 1090-1100. PMID 7686395 DOI: 10.1161/01.Atv.13.7.1090 |
0.312 |
|
| 1993 |
Lupu F, Moldovan N, Ryan J, Stern D, Simionescu N. Intrinsic procoagulant surface induced by hypercholesterolaemia on rabbit aortic endothelium. Blood Coagulation & Fibrinolysis. 4: 743-752. DOI: 10.1097/00001721-199304050-00011 |
0.364 |
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