| Year |
Citation |
Score |
| 2022 |
Li X, Yuan C, Shi J, Kang H, Chen Y, Duan Y, Jin J, Cheung LP, Li TC, Liu Y, Cui Y, Ruan YC, Jiang X, Cai Z, Chan HC, et al. β-Defensin 19/119 mediates sperm chemotaxis and is associated with idiopathic infertility. Cell Reports. Medicine. 100825. PMID 36513070 DOI: 10.1016/j.xcrm.2022.100825 |
0.65 |
|
| 2019 |
Wong TW, Kan CD, Chiu WT, Fok KL, Ruan YC, Jiang X, Chen J, Kao CC, Chen IY, Lin HC, Chou CH, Lin CW, Yu CK, Tsao S, Lee YP, ... Chan HC, et al. Progenitor Cells Derived from Drain Waste Product of Open-Heart Surgery in Children. Journal of Clinical Medicine. 8. PMID 31336927 DOI: 10.3390/Jcm8071028 |
0.619 |
|
| 2018 |
Wang C, Zhang J, Fok KL, Tsang LL, Ye M, Liu J, Li F, Zhao AZ, Chan HC, Chen H. CD147 induces epithelial-to-mesenchymal transition by disassembling CAS/E-cadherin/β-catenin complex in human endometriosis. The American Journal of Pathology. PMID 29630856 DOI: 10.1016/J.Ajpath.2018.03.004 |
0.629 |
|
| 2018 |
Li X, Fok KL, Guo J, Wang Y, Liu Z, Chen Z, Wang C, Ruan YC, Yu SS, Zhao H, Wu J, Jiang X, Chan HC. Retinoic acid promotes stem cell differentiation and embryonic development by transcriptionally activating CFTR. Biochimica Et Biophysica Acta. PMID 29326073 DOI: 10.1016/J.Bbamcr.2018.01.005 |
0.636 |
|
| 2017 |
Diao R, Wang T, Fok KL, Li X, Ruan Y, Yu MK, Cheng Y, Chen Y, Chen H, Mou L, Cai X, Wang Y, Cai Z, Zeng X, Chan HC. CCR6 is required for ligand-induced CatSper activation in human sperm. Oncotarget. 8: 91445-91458. PMID 29207656 DOI: 10.18632/Oncotarget.20651 |
0.647 |
|
| 2017 |
Fok KL, Bose R, Sheng K, Chang CW, Katz-Egorov M, Culty M, Su S, Yang M, Ruan YC, Chan HC, Iavarone A, Lasorella A, Cencic R, Pelletier J, Nagano M, et al. Huwe1 Regulates the Establishment and Maintenance of Spermatogonia by Suppressing DNA Damage Response. Endocrinology. PMID 28938460 DOI: 10.1210/En.2017-00396 |
0.649 |
|
| 2016 |
Wang C, Fok KL, Cai Z, Chen H, Chan HC. CD147 regulates extrinsic apoptosis in spermatocytes by modulating NFκB signaling pathways. Oncotarget. PMID 27902973 DOI: 10.18632/Oncotarget.13624 |
0.639 |
|
| 2016 |
Lu YC, Yang J, Fok KL, Ye YH, Jin L, Chen ZY, Zhang XM, Huang HF, Chan HC. Involvement of Cl(-)/HCO3(-) exchanger SLC26A3 and SLC26A6 in preimplantation embryo cleavage. Scientific Reports. 6: 28402. PMID 27346053 DOI: 10.1038/Srep28402 |
0.652 |
|
| 2015 |
Chang KC, Lee AS, Chen WY, Lin YN, Hsu JF, Chan HC, Chang CM, Chang SS, Pan CC, Sawamura T, Chang CT, Su MJ, Chen CH. Increased LDL electronegativity in chronic kidney disease disrupts calcium homeostasis resulting in cardiac dysfunction. Journal of Molecular and Cellular Cardiology. 84: 36-44. PMID 25871829 DOI: 10.1016/j.yjmcc.2015.03.016 |
0.446 |
|
| 2014 |
Diao R, Fok KL, Chen H, Yu MK, Duan Y, Chung CM, Li Z, Wu H, Li Z, Zhang H, Ji Z, Zhen W, Ng CF, Gui Y, Cai Z, ... Chan HC, et al. Deficient human β-defensin 1 underlies male infertility associated with poor sperm motility and genital tract infection. Science Translational Medicine. 6: 249ra108. PMID 25122636 DOI: 10.1126/Scitranslmed.3009071 |
0.65 |
|
| 2014 |
Guo JH, Chen H, Ruan YC, Zhang XL, Zhang XH, Fok KL, Tsang LL, Yu MK, Huang WQ, Sun X, Chung YW, Jiang X, Sohma Y, Chan HC. Glucose-induced electrical activities and insulin secretion in pancreatic islet β-cells are modulated by CFTR. Nature Communications. 5: 4420. PMID 25025956 DOI: 10.1038/Ncomms5420 |
0.628 |
|
| 2014 |
Lee AS, Chen WY, Chan HC, Hsu JF, Shen MY, Chang CM, Bair H, Su MJ, Chang KC, Chen CH. Gender disparity in LDL-induced cardiovascular damage and the protective role of estrogens against electronegative LDL. Cardiovascular Diabetology. 13: 64. PMID 24666525 DOI: 10.1186/1475-2840-13-64 |
0.455 |
|
| 2014 |
Fok KL, Chen H, Ruan YC, Chan HC. Novel regulators of spermatogenesis. Seminars in Cell & Developmental Biology. 29: 31-42. PMID 24594193 DOI: 10.1016/J.Semcdb.2014.02.008 |
0.638 |
|
| 2013 |
Diao R, Fok KL, Zhao L, Chen H, Tang H, Chen J, Zheng A, Zhang X, Gui Y, Chan HC, Cai Z. Decreased expression of cystic fibrosis transmembrane conductance regulator impairs sperm quality in aged men. Reproduction (Cambridge, England). 146: 637-45. PMID 24077955 DOI: 10.1530/REP-13-0146 |
0.641 |
|
| 2013 |
Zhang JT, Jiang XH, Xie C, Cheng H, Da Dong J, Wang Y, Fok KL, Zhang XH, Sun TT, Tsang LL, Chen H, Sun XJ, Chung YW, Cai ZM, Jiang WG, ... Chan HC, et al. Downregulation of CFTR promotes epithelial-to-mesenchymal transition and is associated with poor prognosis of breast cancer. Biochimica Et Biophysica Acta. 1833: 2961-9. PMID 23916755 DOI: 10.1016/J.Bbamcr.2013.07.021 |
0.647 |
|
| 2013 |
Xie C, Jiang XH, Zhang JT, Sun TT, Dong JD, Sanders AJ, Diao RY, Wang Y, Fok KL, Tsang LL, Yu MK, Zhang XH, Chung YW, Ye L, Zhao MY, ... ... Chan HC, et al. CFTR suppresses tumor progression through miR-193b targeting urokinase plasminogen activator (uPA) in prostate cancer. Oncogene. 32: 2282-91, 2291.e1-7. PMID 22797075 DOI: 10.1038/Onc.2012.251 |
0.631 |
|
| 2012 |
Zhang XH, Ma ZG, Rowlands DK, Gou YL, Fok KL, Wong HY, Yu MK, Tsang LL, Mu L, Chen L, Yung WH, Chung YW, Zhang BL, Zhao H, Chan HC. Flavonoid Myricetin Modulates GABA(A) Receptor Activity through Activation of Ca(2+) Channels and CaMK-II Pathway. Evidence-Based Complementary and Alternative Medicine : Ecam. 2012: 758097. PMID 23258999 DOI: 10.1155/2012/758097 |
0.626 |
|
| 2012 |
Chen J, Fok KL, Chen H, Zhang XH, Xu WM, Chan HC. Cryptorchidism-induced CFTR down-regulation results in disruption of testicular tight junctions through up-regulation of NF-κB/COX-2/PGE2. Human Reproduction (Oxford, England). 27: 2585-97. PMID 22777528 DOI: 10.1093/Humrep/Des254 |
0.643 |
|
| 2012 |
Ruan YC, Guo JH, Liu X, Zhang R, Tsang LL, Dong JD, Chen H, Yu MK, Jiang X, Zhang XH, Fok KL, Chung YW, Huang H, Zhou WL, Chan HC. Activation of the epithelial Na+ channel triggers prostaglandin Eâ‚‚ release and production required for embryo implantation. Nature Medicine. 18: 1112-7. PMID 22729284 DOI: 10.1038/Nm.2771 |
0.63 |
|
| 2012 |
Lu YC, Chen H, Fok KL, Tsang LL, Yu MK, Zhang XH, Chen J, Jiang X, Chung YW, Ma AC, Leung AY, Huang HF, Chan HC. CFTR mediates bicarbonate-dependent activation of miR-125b in preimplantation embryo development. Cell Research. 22: 1453-66. PMID 22664907 DOI: 10.1038/Cr.2012.88 |
0.624 |
|
| 2012 |
Wu W, Song W, Li S, Ouyang S, Fok KL, Diao R, Miao S, Chan HC, Wang L. Regulation of apoptosis by Bat3-enhanced YWK-II/APLP2 protein stability. Journal of Cell Science. 125: 4219-29. PMID 22641691 DOI: 10.1242/Jcs.086553 |
0.637 |
|
| 2012 |
Tang XX, Fok KL, Chen H, Chan KS, Tsang LL, Rowlands DK, Zhang XH, Dong JD, Ruan YC, Jiang X, Yu SS, Chung YW, Chan HC. Lymphocyte CFTR promotes epithelial bicarbonate secretion for bacterial killing. Journal of Cellular Physiology. 227: 3887-94. PMID 22552906 DOI: 10.1002/Jcp.24101 |
0.663 |
|
| 2012 |
Chen H, Fok KL, Jiang X, Jiang J, Chen Z, Gui Y, Chan HC, Cai Z. CD147 regulates apoptosis in mouse spermatocytes but not spermatogonia. Human Reproduction (Oxford, England). 27: 1568-76. PMID 22451502 DOI: 10.1093/Humrep/Des050 |
0.635 |
|
| 2012 |
Fu J, Wang Y, Fok KL, Yang D, Qiu Y, Chan HC, Koide SS, Miao S, Wang L. Anti-ACTL7a antibodies: a cause of infertility. Fertility and Sterility. 97: 1226-33.e1-8. PMID 22386842 DOI: 10.1016/J.Fertnstert.2012.02.023 |
0.59 |
|
| 2012 |
Chen H, Guo JH, Lu YC, Ding GL, Yu MK, Tsang LL, Fok KL, Liu XM, Zhang XH, Chung YW, Huang P, Huang H, Chan HC. Impaired CFTR-dependent amplification of FSH-stimulated estrogen production in cystic fibrosis and PCOS. The Journal of Clinical Endocrinology and Metabolism. 97: 923-32. PMID 22170719 DOI: 10.1210/Jc.2011-1363 |
0.639 |
|
| 2011 |
Liu Y, Jiang X, Zhang X, Chen R, Sun T, Fok KL, Dong J, Tsang LL, Yi S, Ruan Y, Guo J, Yu MK, Tian Y, Chung YW, Yang M, ... ... Chan HC, et al. Dedifferentiation-reprogrammed mesenchymal stem cells with improved therapeutic potential. Stem Cells (Dayton, Ohio). 29: 2077-89. PMID 22052697 DOI: 10.1002/Stem.764 |
0.623 |
|
| 2011 |
Xu WM, Chen J, Chen H, Diao RY, Fok KL, Dong JD, Sun TT, Chen WY, Yu MK, Zhang XH, Tsang LL, Lau A, Shi QX, Shi QH, Huang PB, ... Chan HC, et al. Defective CFTR-dependent CREB activation results in impaired spermatogenesis and azoospermia. Plos One. 6: e19120. PMID 21625623 DOI: 10.1371/Journal.Pone.0019120 |
0.73 |
|
| 2011 |
Chen H, Fok KL, Yu S, Jiang J, Chen Z, Gui Y, Cai Z, Chan HC. CD147 is required for matrix metalloproteinases-2 production and germ cell migration during spermatogenesis. Molecular Human Reproduction. 17: 405-14. PMID 21343160 DOI: 10.1093/Molehr/Gar013 |
0.628 |
|
| 2010 |
Ajonuma LC, Fok KL, Ho LS, Chan PK, Chow PH, Tsang LL, Wong CH, Chen J, Li S, Rowlands DK, Chung YW, Chan HC. CFTR is required for cellular entry and internalization of Chlamydia trachomatis. Cell Biology International. 34: 593-600. PMID 20178459 DOI: 10.1042/Cbi20090227 |
0.658 |
|
| 2010 |
Xu W, Zhang X, Chen W, Fok KL, Rowlands DK, Chui YL, Chan HC. Immunization with Bin1b decreases sperm motility with compromised fertility in rats. Fertility and Sterility. 93: 952-958.e1. PMID 19135192 DOI: 10.1016/J.Fertnstert.2008.10.066 |
0.668 |
|
| 2010 |
Xu W, Wong HYC, Chen W, Shi Q, Chen H, Yu MK, Chan HC, Tierney ML. GABA-A receptor δ subunit is expressed in sperm and important for progesterone-induced AR reaction Cell Biology International. 34: S13-S13. DOI: 10.1042/Cbi034S013D |
0.443 |
|
| 2010 |
Chen H, Fok KL, Gui Y, Cai Z, Chan HC. Co-localization of CD147 and matrix metalloproteinases and its implication for spermatogenesis during mouse testis development Cell Biology International. 34: S8-S8. DOI: 10.1042/Cbi034S008B |
0.611 |
|
| 2009 |
Jin JY, Chen WY, Zhou CX, Chen ZH, Yu-Ying Y, Ni Y, Chan HC, Shi QX. Activation of GABAA receptor/Cl- channel and capacitation in rat spermatozoa: HCO3- and Cl- are essential. Systems Biology in Reproductive Medicine. 55: 97-108. PMID 19462289 DOI: 10.1080/19396360802626648 |
0.461 |
|
| 2009 |
Yin L, Chung CM, Huo R, Liu H, Zhou C, Xu W, Zhu H, Zhang J, Shi Q, Wong HY, Chen J, Lu Y, Bi Y, Zhao C, Du Y, ... ... Chan HC, et al. A sperm GPI-anchored protein elicits sperm-cumulus cross-talk leading to the acrosome reaction. Cellular and Molecular Life Sciences : Cmls. 66: 900-8. PMID 19153666 DOI: 10.1007/S00018-009-8482-2 |
0.695 |
|
| 2009 |
Yin LL, Chung CM, Chen J, Fok KL, Ng CP, Jia RR, Ren X, Zhou J, Zhang T, Zhao XH, Lin M, Zhu H, Zhang XH, Tsang LL, Bi Y, ... ... Chan HC, et al. A suppressor of multiple extracellular matrix-degrading proteases and cancer metastasis. Journal of Cellular and Molecular Medicine. 13: 4034-41. PMID 19017363 DOI: 10.1111/J.1582-4934.2008.00576.X |
0.629 |
|
| 2009 |
Chan HC, Ruan YC, He Q, Chen MH, Chen H, Xu WM, Chen WY, Xie C, Zhang XH, Zhou Z. The cystic fibrosis transmembrane conductance regulator in reproductive health and disease. The Journal of Physiology. 587: 2187-95. PMID 19015188 DOI: 10.1113/jphysiol.2008.164970 |
0.515 |
|
| 2009 |
Chen WY, Xu WM, Chen ZH, Ni Y, Yuan YY, Zhou SC, Zhou WW, Tsang LL, Chung YW, Höglund P, Chan HC, Shi QX. Cl- is required for HCO3- entry necessary for sperm capacitation in guinea pig: involvement of a Cl-/HCO3- exchanger (SLC26A3) and CFTR. Biology of Reproduction. 80: 115-23. PMID 18784352 DOI: 10.1095/biolreprod.108.068528 |
0.513 |
|
| 2008 |
Ajonuma LC, Chan PK, Ng EH, Fok KL, Wong CH, Tsang LL, Tang XX, Ho LS, Lau MC, Chung CM, He Q, Huang HY, Yang DZ, Rowlands DK, Chung YW, ... Chan HC, et al. Involvement of cystic fibrosis transmembrane conductance regulator (CFTR) in the pathogenesis of hydrosalpinx induced by Chlamydia trachomatis infection. The Journal of Obstetrics and Gynaecology Research. 34: 923-30. PMID 19012687 DOI: 10.1111/J.1447-0756.2008.00826.X |
0.652 |
|
| 2008 |
Wang Y, Guan X, Fok KL, Li S, Zhang X, Miao S, Zong S, Koide SS, Chan HC, Wang L. A novel member of the Rhomboid family, RHBDD1, regulates BIK-mediated apoptosis. Cellular and Molecular Life Sciences : Cmls. 65: 3822-9. PMID 18953687 DOI: 10.1007/s00018-008-8452-0 |
0.625 |
|
| 2008 |
Ajonuma LC, He Q, Sheung Chan PK, Yu Ng EH, Fok KL, Yan Wong CH, Tsang LL, Ho LS, Lau MC, Huang HY, Yang DZ, Rowlands DK, Tang XX, Zhang XH, Chung YW, ... Chan HC, et al. Involvement of cystic fibrosis transmembrane conductance regulator in infection-induced edema. Cell Biology International. 32: 801-6. PMID 18462959 DOI: 10.1016/J.Cellbi.2008.03.010 |
0.641 |
|
| 2008 |
Chen W, Xu W, Chen Z, Ni Y, Yuan Y, Zhou S, Li K, Tsang L, Chung YW, Shi Q, Chan HC. Cl- is required for HCO3- entry necessary for sperm capacitation:involvement of a Cl-/HCO3- exchanger(SLC26A3) and CFTR. Biology of Reproduction. 78: 187-187. DOI: 10.1093/Biolreprod/78.S1.187A |
0.476 |
|
| 2008 |
Zhang XH, Rowlands DK, Ma ZG, Gou YL, Tsang LL, Wong HY, Fok KL, Chung YW, Mu L, Chan HC. Herbal extract ECBRC-AG and its active intgredient reduces HPA axis funtion by inhibiting PVN neurons activity through T-type calcium channels Cell Biology International. 32: S66-S67. DOI: 10.1016/J.Cellbi.2008.01.283 |
0.604 |
|
| 2008 |
Xu WM, Chen WY, Dong HS, Fok KL, Zhou CX, Zhu H, Yan Wong CH, Chan HC. The functional role of CFTR in spermatogenesis Cell Biology International. 32: S65-S65. DOI: 10.1016/J.Cellbi.2008.01.278 |
0.624 |
|
| 2007 |
Xu WM, Shi QX, Chen WY, Zhou CX, Ni Y, Rowlands DK, Yi Liu G, Zhu H, Ma ZG, Wang XF, Chen ZH, Zhou SC, Dong HS, Zhang XH, Chung YW, ... ... Chan HC, et al. Cystic fibrosis transmembrane conductance regulator is vital to sperm fertilizing capacity and male fertility. Proceedings of the National Academy of Sciences of the United States of America. 104: 9816-21. PMID 17519339 DOI: 10.1073/Pnas.0609253104 |
0.523 |
|
| 2007 |
Yin X, Ouyang S, Xu W, Zhang X, Fok KL, Wong HY, Zhang J, Qiu X, Miao S, Chan HC, Wang L. YWK-II protein as a novel G(o)-coupled receptor for Müllerian inhibiting substance in cell survival. Journal of Cell Science. 120: 1521-8. PMID 17452623 DOI: 10.1242/Jcs.001230 |
0.645 |
|
| 2007 |
Xu W, Zhou C, Zhang X, Chen W, Zhu H, Chan HC. Bin1b IMMUNIZATION IN RATS RESULTS IN DECREASED SPERM MOTILITY WITH COMPROMISED FERTILIZING CAPACITY Biology of Reproduction. 77: 124-124. DOI: 10.1093/Biolreprod/77.S1.124A |
0.438 |
|
| 2006 |
Shu C, Li TY, Tsang LL, Fok KL, Lo PS, Zhu JX, Ho LS, Chung YW, Chan HC. Differentiation of adult rat bone marrow stem cells into epithelial progenitor cells in culture. Cell Biology International. 30: 823-8. PMID 16877014 DOI: 10.1016/J.Cellbi.2006.06.004 |
0.645 |
|
| 2006 |
Chan HC, Shi QX, Zhou CX, Wang XF, Xu WM, Chen WY, Chen AJ, Ni Y, Yuan YY. Critical role of CFTR in uterine bicarbonate secretion and the fertilizing capacity of sperm. Molecular and Cellular Endocrinology. 250: 106-13. PMID 16414184 DOI: 10.1016/j.mce.2005.12.032 |
0.561 |
|
| 2005 |
Yang JZ, Ajonuma LC, Rowlands DK, Tsang LL, Ho LS, Lam SY, Chen WY, Zhou CX, Chung YW, Cho CY, Tse JY, James AE, Chan HC. The role of inducible nitric oxide synthase in gamete interaction and fertilization: a comparative study on knockout mice of three NOS isoforms. Cell Biology International. 29: 785-91. PMID 16087361 DOI: 10.1016/j.cellbi.2005.05.005 |
0.497 |
|
| 2000 |
Chan LN, Wang XF, Tsang LL, Liu CQ, Chan HC. Suppression of CFTR-mediated Cl- secretion by enhanced expression of epithelial Na+ channels in mouse endometrial epithelium Biochemical and Biophysical Research Communications. 276: 40-44. PMID 11006079 DOI: 10.1006/Bbrc.2000.3426 |
0.363 |
|
| 2000 |
Chan LN, Wang XF, Tsang LL, Chan HC. Pyrimidinoceptors-mediated activation of Ca2+-dependent Cl- conductance in mouse endometrial epithelial cells Biochimica Et Biophysica Acta - Molecular Cell Research. 1497: 261-270. PMID 10903431 DOI: 10.1016/S0167-4889(00)00057-4 |
0.334 |
|
| 2000 |
Chan HC, Wu WL, So SC, Chung YW, Tsang LL, Wang XF, Yan YC, Luk SC, Siu SS, Tsui SK, Fung KP, Lee CY, Waye MM. Modulation of the Ca(2+)-activated Cl(-) channel by 14-3-3epsilon. Biochemical and Biophysical Research Communications. 270: 581-7. PMID 10753667 DOI: 10.1006/Bbrc.2000.2454 |
0.334 |
|
| 1998 |
Wu WL, So SC, Sun YP, Zhou TS, Yu Y, Chung YW, Wang XF, Bao YD, Yan YC, Chan HC. Functional expression of a Ca2+-activated K+ channel in Xenopus oocytes injected with RNAs from the rat testis. Biochimica Et Biophysica Acta. 1373: 360-5. PMID 9733997 DOI: 10.1016/S0005-2736(98)00119-9 |
0.305 |
|
| 1998 |
Wu WL, So SC, Sun YP, Chung YW, Grima J, Wong PY, Yan YC, Chan HC. Functional expression of P2U receptors in rat spermatogenic cells: dual modulation of a Ca(2+)-activated K+ channel. Biochemical and Biophysical Research Communications. 248: 728-32. PMID 9703995 DOI: 10.1006/Bbrc.1998.9051 |
0.33 |
|
| 1998 |
Chan HC, Lui KM, Wong WS, Poon AM. Effect of melatonin on chloride secretion by human colonic T84 cells. Life Sciences. 62: 2151-8. PMID 9627094 DOI: 10.1016/S0024-3205(98)00190-8 |
0.346 |
|
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