| Year |
Citation |
Score |
| 2017 |
Walker JA, Vuyyuru R, Manser T, Alugupalli KR. Humoral Immunity in Mice Transplanted with Hematopoietic Stem Cells Derived from Human Umbilical Cord Blood Recapitulates That of Human Infants. Stem Cells and Development. PMID 29099340 DOI: 10.1089/Scd.2017.0156 |
0.36 |
|
| 2016 |
Quách TD, Hopkins TJ, Holodick NE, Vuyyuru R, Manser T, Bayer RL, Rothstein TL. Human B-1 and B-2 B Cells Develop from Lin-CD34+CD38lo Stem Cells. Journal of Immunology (Baltimore, Md. : 1950). 197: 3950-3958. PMID 27815443 DOI: 10.4049/Jimmunol.1600630 |
0.565 |
|
| 2016 |
Banerjee A, Sindhava V, Vuyyuru R, Jha V, Hodewadekar S, Manser T, Atchison ML. YY1 Is Required for Germinal Center B Cell Development. Plos One. 11: e0155311. PMID 27167731 DOI: 10.1371/Journal.Pone.0155311 |
0.691 |
|
| 2015 |
Vuyyuru R, Shen S, Manser T. Testing the role of the FcγRIIB immunoreceptor tyrosine-based inhibitory motif in regulation of the B cell immune response. Immunity, Inflammation and Disease. 3: 247-64. PMID 26417440 DOI: 10.1002/Iid3.64 |
0.609 |
|
| 2015 |
Patton J, Vuyyuru R, Siglin A, Root M, Manser T. Evaluation of the efficiency of human immune system reconstitution in NSG mice and NSG mice containing a human HLA.A2 transgene using hematopoietic stem cells purified from different sources. Journal of Immunological Methods. 422: 13-21. PMID 25776756 DOI: 10.1016/J.Jim.2015.02.007 |
0.384 |
|
| 2013 |
Nikbakht N, Shen S, Manser T. Cutting edge: Macrophages are required for localization of antigen-activated B cells to the follicular perimeter and the subsequent germinal center response. Journal of Immunology (Baltimore, Md. : 1950). 190: 4923-7. PMID 23567932 DOI: 10.4049/Jimmunol.1300350 |
0.778 |
|
| 2013 |
Landel CP, Dunlap J, Patton JB, Manser T. A germline-competent embryonic stem cell line from NOD.Cg-Prkdc ( scid ) Il2rg ( tm1Wjl )/SzJ (NSG) mice. Transgenic Research. 22: 179-85. PMID 22767020 DOI: 10.1007/S11248-012-9629-8 |
0.415 |
|
| 2012 |
Shen S, Manser T. Direct reduction of antigen receptor expression in polyclonal B cell populations developing in vivo results in light chain receptor editing. Journal of Immunology (Baltimore, Md. : 1950). 188: 47-56. PMID 22131331 DOI: 10.4049/Jimmunol.1102109 |
0.586 |
|
| 2011 |
Vuyyuru R, Liu H, Manser T, Alugupalli KR. Characteristics of Borrelia hermsii infection in human hematopoietic stem cell-engrafted mice mirror those of human relapsing fever. Proceedings of the National Academy of Sciences of the United States of America. 108: 20707-12. PMID 22143787 DOI: 10.1073/Pnas.1108776109 |
0.546 |
|
| 2011 |
Vuyyuru R, Patton J, Manser T. Human immune system mice: current potential and limitations for translational research on human antibody responses. Immunologic Research. 51: 257-66. PMID 22038527 DOI: 10.1007/S12026-011-8243-9 |
0.62 |
|
| 2011 |
Nikbakht N, Migone TS, Ward CP, Manser T. Cellular competition independent of BAFF/B lymphocyte stimulator results in low frequency of an autoreactive clonotype in mature polyclonal B cell compartments. Journal of Immunology (Baltimore, Md. : 1950). 187: 37-46. PMID 21632709 DOI: 10.4049/Jimmunol.1003924 |
0.805 |
|
| 2010 |
Coffey F, Manser T. Expression of cellular FLIP by B cells is required for their participation in an immune response. Journal of Immunology (Baltimore, Md. : 1950). 184: 4871-9. PMID 20335528 DOI: 10.4049/Jimmunol.0903506 |
0.801 |
|
| 2009 |
Schwickert TA, Alabyev B, Manser T, Nussenzweig MC. Germinal center reutilization by newly activated B cells. The Journal of Experimental Medicine. 206: 2907-14. PMID 19934021 DOI: 10.1084/Jem.20091225 |
0.649 |
|
| 2009 |
Vuyyuru R, Mohan C, Manser T, Rahman ZS. The lupus susceptibility locus Sle1 breaches peripheral B cell tolerance at the antibody-forming cell and germinal center checkpoints. Journal of Immunology (Baltimore, Md. : 1950). 183: 5716-27. PMID 19828626 DOI: 10.4049/Jimmunol.0804215 |
0.701 |
|
| 2009 |
Coffey F, Alabyev B, Manser T. Initial clonal expansion of germinal center B cells takes place at the perimeter of follicles. Immunity. 30: 599-609. PMID 19303334 DOI: 10.1016/J.Immuni.2009.01.011 |
0.788 |
|
| 2009 |
Liu X, Shen S, Manser T. Influence of B cell antigen receptor expression level on pathways of B cell tolerance induction. Journal of Immunology (Baltimore, Md. : 1950). 182: 398-407. PMID 19109171 DOI: 10.4049/Jimmunol.182.1.398 |
0.578 |
|
| 2009 |
Zhang H, Rosenberg S, Coffey FJ, He YW, Manser T, Hardy RR, Zhang J. A role for cFLIP in B cell proliferation and stress MAPK regulation. Journal of Immunology (Baltimore, Md. : 1950). 182: 207-15. PMID 19109151 DOI: 10.4049/Jimmunol.182.1.207 |
0.768 |
|
| 2008 |
Alabyev B, Vuyyuru R, Manser T. Influence of Fas on the regulation of the response of an anti-nuclear antigen B cell clonotype to foreign antigen. International Immunology. 20: 1279-87. PMID 18689725 DOI: 10.1093/Intimm/Dxn087 |
0.695 |
|
| 2007 |
Coffey F, Liu X, Manser T. Primary development and participation in a foreign antigen-driven immune response of a chromatin-reactive B cell clonotype are not influenced by TLR9 or other MyD88-dependent TLRs. Journal of Immunology (Baltimore, Md. : 1950). 179: 6663-72. PMID 17982056 DOI: 10.4049/Jimmunol.179.10.6663 |
0.779 |
|
| 2007 |
Rahman ZS, Niu H, Perry D, Wakeland E, Manser T, Morel L. Expression of the autoimmune Fcgr2b NZW allele fails to be upregulated in germinal center B cells and is associated with increased IgG production. Genes and Immunity. 8: 604-12. PMID 17713556 DOI: 10.1038/Sj.Gene.6364423 |
0.66 |
|
| 2007 |
Alabyev B, Rahman ZS, Manser T. Quantitatively reduced participation of anti-nuclear antigen B cells that down-regulate B cell receptor during primary development in the germinal center/memory B cell response to foreign antigen. Journal of Immunology (Baltimore, Md. : 1950). 178: 5623-34. PMID 17442945 DOI: 10.4049/Jimmunol.178.9.5623 |
0.739 |
|
| 2007 |
Liu X, Wysocki LJ, Manser T. Autoantigen-B cell antigen receptor interactions that regulate expression of B cell antigen receptor Loci. Journal of Immunology (Baltimore, Md. : 1950). 178: 5035-47. PMID 17404286 DOI: 10.4049/Jimmunol.178.8.5035 |
0.638 |
|
| 2007 |
Rahman ZS, Alabyev B, Manser T. FcgammaRIIB regulates autoreactive primary antibody-forming cell, but not germinal center B cell, activity. Journal of Immunology (Baltimore, Md. : 1950). 178: 897-907. PMID 17202351 DOI: 10.4049/Jimmunol.178.2.897 |
0.669 |
|
| 2006 |
Imtiyaz HZ, Rosenberg S, Zhang Y, Rahman ZSM, Hou YJ, Manser T, Zhang J. The Fas-associated death domain protein is required in apoptosis and TLR-induced proliferative responses in B cells Journal of Immunology. 176: 6852-6861. PMID 16709845 DOI: 10.4049/Jimmunol.176.11.6852 |
0.612 |
|
| 2005 |
Heltemes-Harris L, Liu X, Manser T. An antibody VH gene that promotes marginal zone B cell development and heavy chain allelic inclusion. International Immunology. 17: 1447-61. PMID 16204304 DOI: 10.1093/Intimm/Dxh323 |
0.558 |
|
| 2005 |
Rahman ZS, Manser T. Failed up-regulation of the inhibitory IgG Fc receptor Fc gamma RIIB on germinal center B cells in autoimmune-prone mice is not associated with deletion polymorphisms in the promoter region of the Fc gamma RIIB gene. Journal of Immunology (Baltimore, Md. : 1950). 175: 1440-9. PMID 16034080 DOI: 10.4049/Jimmunol.175.3.1440 |
0.69 |
|
| 2005 |
Liu X, Manser T. Antinuclear antigen B cells that down-regulate surface B cell receptor during development to mature, follicular phenotype do not display features of anergy in vitro. Journal of Immunology (Baltimore, Md. : 1950). 174: 4505-15. PMID 15814671 DOI: 10.4049/Jimmunol.174.8.4505 |
0.696 |
|
| 2004 |
Rahman ZS, Manser T. B cells expressing Bcl-2 and a signaling-impaired BAFF-specific receptor fail to mature and are deficient in the formation of lymphoid follicles and germinal centers. Journal of Immunology (Baltimore, Md. : 1950). 173: 6179-88. PMID 15528355 DOI: 10.4049/Jimmunol.173.10.6179 |
0.65 |
|
| 2004 |
Manser T. Textbook germinal centers? Journal of Immunology (Baltimore, Md. : 1950). 172: 3369-75. PMID 15004133 DOI: 10.4049/Jimmunol.172.6.3369 |
0.431 |
|
| 2004 |
Heltemes-Harris L, Liu X, Manser T. Progressive surface B cell antigen receptor down-regulation accompanies efficient development of antinuclear antigen B cells to mature, follicular phenotype. Journal of Immunology (Baltimore, Md. : 1950). 172: 823-33. PMID 14707052 DOI: 10.4049/Jimmunol.172.2.823 |
0.704 |
|
| 2003 |
Rahman ZS, Rao SP, Kalled SL, Manser T. Normal induction but attenuated progression of germinal center responses in BAFF and BAFF-R signaling-deficient mice. The Journal of Experimental Medicine. 198: 1157-69. PMID 14557413 DOI: 10.1084/Jem.20030495 |
0.687 |
|
| 2002 |
Notidis E, Heltemes L, Manser T. Dominant, hierarchical induction of peripheral tolerance during foreign antigen-driven B cell development. Immunity. 17: 317-27. PMID 12354384 DOI: 10.1016/S1074-7613(02)00392-8 |
0.627 |
|
| 2002 |
Alabyev B, Manser T. Bcl-2 rescues the germinal center response but does not alter the V gene somatic hypermutation spectrum in MSH2-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 169: 3819-24. PMID 12244177 DOI: 10.4049/Jimmunol.169.7.3819 |
0.531 |
|
| 2002 |
Rao SP, Vora KA, Manser T. Differential expression of the inhibitory IgG Fc receptor FcgammaRIIB on germinal center cells: implications for selection of high-affinity B cells. Journal of Immunology (Baltimore, Md. : 1950). 169: 1859-68. PMID 12165510 DOI: 10.4049/Jimmunol.169.4.1859 |
0.683 |
|
| 2002 |
Heltemes LM, Manser T. Level of B cell antigen receptor surface expression influences both positive and negative selection of B cells during primary development. Journal of Immunology (Baltimore, Md. : 1950). 169: 1283-92. PMID 12133950 DOI: 10.4049/Jimmunol.169.3.1283 |
0.665 |
|
| 2002 |
Manser T. Effector BCRs: inside information on IgG. Nature Immunology. 3: 114-6. PMID 11812985 DOI: 10.1038/Ni0202-114 |
0.569 |
|
| 2001 |
Notidis E, Hande S, Manser T. Enforced expression of Bcl-2 selectively perturbs negative selection of dual reactive antibodies. Developmental Immunology. 8: 223-234. PMID 11785672 DOI: 10.1155/2001/83595 |
0.6 |
|
| 2001 |
Lentz VM, Manser T. Cutting edge: germinal centers can be induced in the absence of T cells. Journal of Immunology (Baltimore, Md. : 1950). 167: 15-20. PMID 11418626 DOI: 10.4049/Jimmunol.167.1.15 |
0.638 |
|
| 2001 |
Tumas-Brundage KM, Notidis E, Heltemes L, Zhang X, Wysocki LJ, Manser T. Predominance of a novel splenic B cell population in mice expressing a transgene that encodes multireactive antibodies: support for additional heterogeneity of the B cell compartment. International Immunology. 13: 475-84. PMID 11282987 DOI: 10.1093/Intimm/13.4.475 |
0.7 |
|
| 2001 |
Vora KA, Lentz VM, Monsell W, Rao SP, Mettus R, Toscani A, Reddy EP, Manser T. The T cell-dependent B cell immune response and germinal center reaction are intact in A-myb-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 166: 3226-30. PMID 11207276 DOI: 10.4049/Jimmunol.166.5.3226 |
0.635 |
|
| 2001 |
Benschop RJ, Aviszus K, Zhang X, Manser T, Cambier JC, Wysocki LJ. Activation and anergy in bone marrow B cells of a novel immunoglobulin transgenic mouse that is both hapten specific and autoreactive. Immunity. 14: 33-43. PMID 11163228 DOI: 10.1016/S1074-7613(01)00087-5 |
0.582 |
|
| 2000 |
Lentz VM, Manser T. Self-limiting systemic autoimmune disease during reconstitution of T cell-deficient mice with syngeneic T cells: support for a multifaceted role of T cells in the maintenance of peripheral B cell tolerance. International Immunology. 12: 1483-97. PMID 11058568 DOI: 10.1093/Intimm/12.11.1483 |
0.637 |
|
| 1999 |
Vora KA, Tumas-Brundage KM, Lentz VM, Cranston A, Fishel R, Manser T. Severe attenuation of the B cell immune response in Msh2-deficient mice Journal of Experimental Medicine. 189: 471-481. PMID 9927509 DOI: 10.1084/Jem.189.3.471 |
0.594 |
|
| 1998 |
Vora KA, Ravetch JV, Manser T. Insights into the mechanisms of antibody-affinity maturation and the generation of the memory B-cell compartment using genetically altered mice. Developmental Immunology. 6: 305-16. PMID 9814604 DOI: 10.1155/1998/42595 |
0.488 |
|
| 1998 |
Manser T, Tumas-Brundage KM, Casson LP, Giusti AM, Hande S, Notidis E, Vora KA. The roles of antibody variable region hypermutation and selection in the development of the memory B-cell compartment. Immunological Reviews. 162: 183-96. PMID 9602364 DOI: 10.1111/J.1600-065X.1998.Tb01441.X |
0.552 |
|
| 1998 |
Hande S, Notidis E, Manser T. Bcl-2 obstructs negative selection of autoreactive, hypermutated antibody V regions during memory B cell development Immunity. 8: 189-198. PMID 9492000 DOI: 10.1016/S1074-7613(00)80471-9 |
0.59 |
|
| 1997 |
Hande S, Manser T. Single amino acid substitutions in VH CDR2 are sufficient to generate or enhance the specificity of two forms of an anti-arsonate antibody variable region for DNA Molecular Immunology. 34: 1281-1290. PMID 9683270 DOI: 10.1016/S0161-5890(98)00005-4 |
0.305 |
|
| 1997 |
Tumas-Brundage K, Manser T. The Transcriptional Promoter Regulates Hypermutation of the Antibody Heavy Chain Locus Journal of Experimental Medicine. 185: 239-250. PMID 9016873 DOI: 10.1084/Jem.185.2.239 |
0.308 |
|
| 1996 |
Tumas-Brundage K, Vora KA, Giusti AM, Manser T. Characterization of the cis-acting elements required for somatic hypermutation of murine antibody V genes using conventional transgenic and transgene homologous recombination approaches. Seminars in Immunology. 8: 141-50. PMID 8738913 DOI: 10.1006/Smim.1996.0018 |
0.329 |
|
| 1995 |
Vora KA, Manser T. Altering the antibody repertoire via transgene homologous recombination: evidence for global and clone-autonomous regulation of antigen-driven B cell differentiation. The Journal of Experimental Medicine. 181: 271-81. PMID 7807007 DOI: 10.1084/Jem.181.1.271 |
0.551 |
|
| 1995 |
Casson LP, Manser T. Random mutagenesis of two complementarity determining region amino acids yields an unexpectedly high frequency of antibodies with increased affinity for both cognate antigen and autoantigen. Journal of Experimental Medicine. 182: 743-750. PMID 7650481 DOI: 10.1084/Jem.182.3.743 |
0.418 |
|
| 1994 |
Giusti AM, Manser T. Somatic Generation of Hybrid Antibody H Chain Genes in Transgenic Mice via Interchromosomal Gene Conversion Journal of Experimental Medicine. 179: 235-248. PMID 8270869 DOI: 10.1084/Jem.179.1.235 |
0.405 |
|
| 1993 |
Giusti AM, Manser T. Hypermutation is observed only in antibody H chain V region transgenes that have recombined with endogenous immunoglobulin H DNA: implications for the location of cis-acting elements required for somatic mutation. Journal of Experimental Medicine. 177: 797-809. PMID 8436910 DOI: 10.1084/Jem.177.3.797 |
0.366 |
|
| 1986 |
Wysocki L, Manser T, Gefter ML. Somatic evolution of variable region structures during an immune response Proceedings of the National Academy of Sciences of the United States of America. 83: 1847-1851. PMID 3485290 DOI: 10.1073/Pnas.83.6.1847 |
0.535 |
|
| 1984 |
Manser T, Huang SY, Gefter ML. Influence of clonal selection on the expression of immunoglobulin variable region genes Science. 226: 1283-1288. PMID 6334361 DOI: 10.1126/Science.6334361 |
0.517 |
|
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