| Year |
Citation |
Score |
| 2021 |
Xu H, George E, Kinose Y, Kim H, Shah JB, Peake JD, Ferman B, Medvedev S, Murtha T, Barger CJ, Devins KM, D'Andrea K, Wubbenhorst B, Schwartz LE, Hwang WT, ... ... Karpf AR, et al. copy number is a biomarker for response to combination WEE1-ATR inhibition in ovarian and endometrial cancer models. Cell Reports. Medicine. 2: 100394. PMID 34622231 DOI: 10.1016/j.xcrm.2021.100394 |
0.362 |
|
| 2021 |
Liu C, Barger CJ, Karpf AR. FOXM1: A Multifunctional Oncoprotein and Emerging Therapeutic Target in Ovarian Cancer. Cancers. 13. PMID 34205406 DOI: 10.3390/cancers13123065 |
0.32 |
|
| 2021 |
Barger CJ, Chee L, Albahrani M, Munoz-Trujillo C, Boghean L, Branick C, Odunsi K, Drapkin R, Zou L, Karpf AR. Co-regulation and function of / bidirectional genes in cancer. Elife. 10. PMID 33890574 DOI: 10.7554/eLife.55070 |
0.436 |
|
| 2020 |
Kim O, Park EY, Klinkebiel DL, Pack SD, Shin YH, Abdullaev Z, Emerson RE, Coffey DM, Kwon SY, Creighton CJ, Kwon S, Chang EC, Chiang T, Yatsenko AN, Chien J, ... ... Karpf AR, et al. In vivo modeling of metastatic human high-grade serous ovarian cancer in mice. Plos Genetics. 16: e1008808. PMID 32497036 DOI: 10.1371/Journal.Pgen.1008808 |
0.366 |
|
| 2020 |
Zhang W, Klinkebiel D, Barger CJ, Pandey S, Guda C, Miller A, Akers SN, Odunsi K, Karpf AR. Global DNA Hypomethylation in Epithelial Ovarian Cancer: Passive Demethylation and Association with Genomic Instability. Cancers. 12. PMID 32213861 DOI: 10.3390/Cancers12030764 |
0.559 |
|
| 2019 |
Haque M, Li J, Huang YH, Almowaled M, Barger CJ, Karpf AR, Wang P, Chen W, Turner SD, Lai R. NPM-ALK Is a Key Regulator of the Oncoprotein FOXM1 in ALK-Positive Anaplastic Large Cell Lymphoma. Cancers. 11. PMID 31390744 DOI: 10.3390/Cancers11081119 |
0.313 |
|
| 2019 |
Hillman JC, Pugacheva EM, Barger CJ, Sribenja S, Rosario S, Albahrani M, Truskinovsky AM, Stablewski A, Liu S, Loukinov DI, Zentner GE, Lobanenkov VV, Karpf AR, Higgins MJ. BORIS expression in ovarian cancer precursor cells alters the CTCF cistrome and enhances invasiveness through GALNT14. Molecular Cancer Research : McR. PMID 31292201 DOI: 10.1158/1541-7786.MCR-19-0310 |
0.421 |
|
| 2019 |
Barger CJ, Branick C, Chee L, Karpf AR. Pan-Cancer Analyses Reveal Genomic Features of FOXM1 Overexpression in Cancer. Cancers. 11. PMID 30795624 DOI: 10.3390/cancers11020251 |
0.422 |
|
| 2019 |
Sharma A, Albahrani M, Zhang W, Kufel CN, James SR, Odunsi K, Klinkebiel D, Karpf AR. Epigenetic activation of POTE genes in ovarian cancer. Epigenetics. PMID 30764732 DOI: 10.1080/15592294.2019.1581590 |
0.543 |
|
| 2018 |
Barger CJ, Zhang W, Sharma A, Chee L, James SR, Kufel CN, Miller A, Meza J, Drapkin R, Odunsi K, Klinkebiel D, Karpf AR. Expression of the POTE gene family in human ovarian cancer. Scientific Reports. 8: 17136. PMID 30459449 DOI: 10.1038/s41598-018-35567-1 |
0.376 |
|
| 2018 |
Wang P, Haque M, Li J, Huang Y, Almowaled M, Bargar C, Karpf A, Chen W, Turner S, Lai R. FOXM1 and the NPM-ALK/STAT3 Axis Form a Novel Positive Feedback Loop in Promoting the Oncogenesis of ALK-Positive Anaplastic Large Cell Lymphoma Blood. 132: 3921-3921. DOI: 10.1182/Blood-2018-99-115743 |
0.41 |
|
| 2017 |
Sturgeon SR, Pilsner JR, Arcaro KF, Ikuma K, Wu H, Kim SM, Chopra-Tandon N, Karpf AR, Ziegler RG, Schairer C, Balasubramanian R, Reckhow DA. White blood cell DNA methylation and risk of breast cancer in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO). Breast Cancer Research : Bcr. 19: 94. PMID 28821281 DOI: 10.1186/S13058-017-0886-6 |
0.48 |
|
| 2016 |
Zhang W, Barger CJ, Eng KH, Klinkebiel D, Link PA, Omilian A, Bshara W, Odunsi K, Karpf AR. PRAME expression and promoter hypomethylation in epithelial ovarian cancer. Oncotarget. PMID 27322684 DOI: 10.18632/Oncotarget.9977 |
0.477 |
|
| 2016 |
Klinkebiel D, Zhang W, Akers SN, Odunsi K, Karpf AR. DNA Methylome Analyses Implicate Fallopian Tube Epithelia as the Origin for High-grade Serous Ovarian Cancer. Molecular Cancer Research : McR. PMID 27259716 DOI: 10.1158/1541-7786.MCR-16-0097 |
0.479 |
|
| 2016 |
Haney SL, Upchurch GM, Opavska J, Klinkebiel D, Hlady RA, Suresh A, Pirruccello SJ, Shukla V, Lu R, Costinean S, Rizzino A, Karpf AR, Joshi S, Swanson P, Opavsky R. Promoter Hypomethylation and Expression Is Conserved in Mouse Chronic Lymphocytic Leukemia Induced by Decreased or Inactivated Dnmt3a. Cell Reports. PMID 27134162 DOI: 10.1016/J.Celrep.2016.04.004 |
0.433 |
|
| 2016 |
Srivastava P, Paluch BE, Matsuzaki J, James SR, Collamat-Lai G, Blagitko-Dorfs N, Ford LA, Naqash R, Lübbert M, Karpf AR, Nemeth MJ, Griffiths EA. Induction of cancer testis antigen expression in circulating acute myeloid leukemia blasts following hypomethylating agent monotherapy. Oncotarget. 7: 12840-56. PMID 26883197 DOI: 10.18632/oncotarget.7326 |
0.331 |
|
| 2015 |
Barger CJ, Zhang W, Hillman J, Stablewski AB, Higgins MJ, Vanderhyden BC, Odunsi K, Karpf AR. Genetic determinants of FOXM1 overexpression in epithelial ovarian cancer and functional contribution to cell cycle progression. Oncotarget. 6: 27613-27. PMID 26243836 DOI: 10.18632/oncotarget.4546 |
0.377 |
|
| 2015 |
Zhang W, Barger C, Link P, Mhawech-Fauceglia P, Miller A, Akers S, Odunsi K, Karpf AR. DNA hypomethylation-mediated activation of Cancer/Testis Antigen 45 (CT45) genes is associated with disease progression and reduced survival in epithelial ovarian cancer. Epigenetics : Official Journal of the Dna Methylation Society. 0. PMID 26098711 DOI: 10.1080/15592294.2015.1062206 |
0.327 |
|
| 2015 |
Srivastava P, Paluch BE, Matsuzaki J, James SR, Collamat-Lai G, Taverna P, Karpf AR, Griffiths EA. Immunomodulatory action of the DNA methyltransferase inhibitor SGI-110 in epithelial ovarian cancer cells and xenografts. Epigenetics. 10: 237-46. PMID 25793777 DOI: 10.1080/15592294.2015.1017198 |
0.358 |
|
| 2014 |
Odunsi K, Matsuzaki J, James SR, Mhawech-Fauceglia P, Tsuji T, Miller A, Zhang W, Akers SN, Griffiths EA, Miliotto A, Beck A, Batt CA, Ritter G, Lele S, Gnjatic S, ... Karpf AR, et al. Epigenetic potentiation of NY-ESO-1 vaccine therapy in human ovarian cancer. Cancer Immunology Research. 2: 37-49. PMID 24535937 DOI: 10.1158/2326-6066.Cir-13-0126 |
0.433 |
|
| 2014 |
Akers SN, Moysich K, Zhang W, Collamat Lai G, Miller A, Lele S, Odunsi K, Karpf AR. LINE1 and Alu repetitive element DNA methylation in tumors and white blood cells from epithelial ovarian cancer patients. Gynecologic Oncology. 132: 462-7. PMID 24374023 DOI: 10.1016/J.Ygyno.2013.12.024 |
0.494 |
|
| 2013 |
Peters SL, Hlady RA, Opavska J, Klinkebiel D, Novakova S, Smith LM, Lewis RE, Karpf AR, Simpson MA, Wu L, Opavsky R. Essential role for Dnmt1 in the prevention and maintenance of MYC-induced T-cell lymphomas. Molecular and Cellular Biology. 33: 4321-33. PMID 24001767 DOI: 10.1128/Mcb.00776-13 |
0.488 |
|
| 2013 |
James SR, Cedeno CD, Sharma A, Zhang W, Mohler JL, Odunsi K, Wilson EM, Karpf AR. DNA methylation and nucleosome occupancy regulate the cancer germline antigen gene MAGEA11. Epigenetics : Official Journal of the Dna Methylation Society. 8: 849-63. PMID 23839233 DOI: 10.4161/epi.25500 |
0.659 |
|
| 2013 |
Link PA, Zhang W, Odunsi K, Karpf AR. BORIS/CTCFL mRNA isoform expression and epigenetic regulation in epithelial ovarian cancer. Cancer Immunity. 13: 6. PMID 23390377 |
0.485 |
|
| 2013 |
Vasanthakumar A, Lepore JB, Zegarek MH, Kocherginsky M, Singh M, Davis EM, Link PA, Anastasi J, Le Beau MM, Karpf AR, Godley LA. Dnmt3b is a haploinsufficient tumor suppressor gene in Myc-induced lymphomagenesis. Blood. 121: 2059-63. PMID 23315164 DOI: 10.1182/Blood-2012-04-421065 |
0.534 |
|
| 2011 |
Liu L, van Groen T, Kadish I, Li Y, Wang D, James SR, Karpf AR, Tollefsbol TO. Insufficient DNA methylation affects healthy aging and promotes age-related health problems. Clinical Epigenetics. 2: 349-60. PMID 22704347 DOI: 10.1007/S13148-011-0042-6 |
0.395 |
|
| 2011 |
Deeb KK, Luo W, Karpf AR, Omilian AR, Bshara W, Tian L, Tangrea MA, Morrison CD, Johnson CS, Trump DL. Differential vitamin D 24-hydroxylase/CYP24A1 gene promoter methylation in endothelium from benign and malignant human prostate. Epigenetics : Official Journal of the Dna Methylation Society. 6: 994-1000. PMID 21725204 DOI: 10.4161/Epi.6.8.16536 |
0.492 |
|
| 2011 |
Woloszynska-Read A, Zhang W, Yu J, Link PA, Mhawech-Fauceglia P, Collamat G, Akers SN, Ostler KR, Godley LA, Odunsi K, Karpf AR. Coordinated cancer germline antigen promoter and global DNA hypomethylation in ovarian cancer: association with the BORIS/CTCF expression ratio and advanced stage. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 2170-80. PMID 21296871 DOI: 10.1158/1078-0432.Ccr-10-2315 |
0.774 |
|
| 2011 |
Griffiths EA, Karpf AR, Odunsi K, James SR, Beck AF, Wetzler M, Ford LA. Conventional Dose Hypomethylating Agents Induce CG Antigen Genes In Vivo Blood. 118: 2441-2441. DOI: 10.1182/Blood.V118.21.2441.2441 |
0.367 |
|
| 2011 |
Akers S, Moysich K, Zhang W, Link P, Miller A, Lele S, Odunsi K, Karpf A. Association between global DNA hypomethylation in leukocytes and risk of ovarian cancer Gynecologic Oncology. 120: S43-S44. DOI: 10.1016/J.Ygyno.2010.12.107 |
0.525 |
|
| 2010 |
Woloszynska-Read A, James SR, Song C, Jin B, Odunsi K, Karpf AR. BORIS/CTCFL expression is insufficient for cancer-germline antigen gene expression and DNA hypomethylation in ovarian cell lines. Cancer Immunity. 10: 6. PMID 20649179 |
0.777 |
|
| 2010 |
Luo W, Karpf AR, Deeb KK, Muindi JR, Morrison CD, Johnson CS, Trump DL. Epigenetic regulation of vitamin D 24-hydroxylase/CYP24A1 in human prostate cancer. Cancer Research. 70: 5953-62. PMID 20587525 DOI: 10.1158/0008-5472.Can-10-0617 |
0.609 |
|
| 2010 |
Kinney SR, Moser MT, Pascual M, Greally JM, Foster BA, Karpf AR. Opposing roles of Dnmt1 in early- and late-stage murine prostate cancer. Molecular and Cellular Biology. 30: 4159-74. PMID 20584988 DOI: 10.1128/Mcb.00235-10 |
0.589 |
|
| 2010 |
Akers SN, Odunsi K, Karpf AR. Regulation of cancer germline antigen gene expression: implications for cancer immunotherapy. Future Oncology (London, England). 6: 717-32. PMID 20465387 DOI: 10.2217/fon.10.36 |
0.456 |
|
| 2010 |
Starlard-Davenport A, Tryndyak VP, James SR, Karpf AR, Latendresse JR, Beland FA, Pogribny IP. Mechanisms of epigenetic silencing of the Rassf1a gene during estrogen-induced breast carcinogenesis in ACI rats Carcinogenesis. 31: 376-381. PMID 20008439 DOI: 10.1093/Carcin/Bgp304 |
0.363 |
|
| 2010 |
Rai K, Jafri IF, Chidester S, James SR, Karpf AR, Cairns BR, Jones DA. Dnmt3 and G9a cooperate for tissue-specific development in zebrafish. The Journal of Biological Chemistry. 285: 4110-21. PMID 19946145 DOI: 10.1074/Jbc.M109.073676 |
0.318 |
|
| 2009 |
Morey Kinney SR, Zhang W, Pascual M, Greally JM, Gillard BM, Karasik E, Foster BA, Karpf AR. Lack of evidence for green tea polyphenols as DNA methylation inhibitors in murine prostate. Cancer Prevention Research (Philadelphia, Pa.). 2: 1065-75. PMID 19934341 DOI: 10.1158/1940-6207.Capr-09-0010 |
0.727 |
|
| 2009 |
Choi JY, James SR, Link PA, Mccann SE, Hong CC, Davis W, Nesline MK, Ambrosone CB, Karpf AR. Association between global DNA hypomethylation in leukocytes and risk of breast cancer Carcinogenesis. 30: 1889-1897. PMID 19584139 DOI: 10.1093/carcin/bgp143 |
0.386 |
|
| 2009 |
Link PA, Gangisetty O, James SR, Woloszynska-Read A, Tachibana M, Shinkai Y, Karpf AR. Distinct roles for histone methyltransferases G9a and GLP in cancer germ-line antigen gene regulation in human cancer cells and murine embryonic stem cells. Molecular Cancer Research : McR. 7: 851-62. PMID 19531572 DOI: 10.1158/1541-7786.Mcr-08-0497 |
0.77 |
|
| 2009 |
Mavis CK, Morey Kinney SR, Foster BA, Karpf AR. Expression level and DNA methylation status of glutathione-S-transferase genes in normal murine prostate and TRAMP tumors. The Prostate. 69: 1312-24. PMID 19444856 DOI: 10.1002/pros.20976 |
0.737 |
|
| 2009 |
Karpf AR, Bai S, James SR, Mohler JL, Wilson EM. Increased expression of androgen receptor coregulator MAGE-11 in prostate cancer by DNA hypomethylation and cyclic AMP. Molecular Cancer Research : McR. 7: 523-35. PMID 19372581 DOI: 10.1158/1541-7786.MCR-08-0400 |
0.629 |
|
| 2008 |
Rai K, Huggins IJ, James SR, Karpf AR, Jones DA, Cairns BR. DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45. Cell. 135: 1201-12. PMID 19109892 DOI: 10.1016/J.Cell.2008.11.042 |
0.456 |
|
| 2008 |
Link PA, Baer MR, James SR, Jones DA, Karpf AR. P53-inducible ribonucleotide reductase (P53R2/RRM2B) is a DNA hypomethylation-independent decitabine gene target that correlates with clinical response in myelodysplastic syndrome/acute myelogenous leukemia Cancer Research. 68: 9358-9366. PMID 19010910 DOI: 10.1158/0008-5472.CAN-08-1860 |
0.447 |
|
| 2008 |
Pogribny IP, Karpf AR, James SR, Melnyk S, Han T, Tryndyak VP. Epigenetic alterations in the brains of Fisher 344 rats induced by long-term administration of folate/methyl-deficient diet Brain Research. 1237: 25-34. PMID 18694733 DOI: 10.1016/j.brainres.2008.07.077 |
0.426 |
|
| 2008 |
Morey Kinney SR, Smiraglia DJ, James SR, Moser MT, Foster BA, Karpf AR. Stage-specific alterations of DNA methyltransferase expression, DNA hypermethylation, and DNA hypomethylation during prostate cancer progression in the transgenic adenocarcinoma of mouse prostate model. Molecular Cancer Research : McR. 6: 1365-74. PMID 18667590 DOI: 10.1158/1541-7786.Mcr-08-0040 |
0.739 |
|
| 2008 |
Woloszynska-Read A, Mhawech-Fauceglia P, Yu J, Odunsi K, Karpf AR. Intertumor and intratumor NY-ESO-1 expression heterogeneity is associated with promoter-specific and global DNA methylation status in ovarian cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 3283-90. PMID 18519754 DOI: 10.1158/1078-0432.Ccr-07-5279 |
0.78 |
|
| 2008 |
Camoriano M, Kinney SR, Moser MT, Foster BA, Mohler JL, Trump DL, Karpf AR, Smiraglia DJ. Phenotype-specific CpG island methylation events in a murine model of prostate cancer. Cancer Research. 68: 4173-82. PMID 18519676 DOI: 10.1158/0008-5472.Can-07-6715 |
0.614 |
|
| 2007 |
Woloszynska-Read A, James SR, Link PA, Yu J, Odunsi K, Karpf AR. DNA methylation-dependent regulation of BORIS/CTCFL expression in ovarian cancer. Cancer Immunity. 7: 21. PMID 18095639 |
0.797 |
|
| 2007 |
Karpf AR. Epigenomic reactivation screening to identify genes silenced by DNA hypermethylation in human cancer. Current Opinion in Molecular Therapeutics. 9: 231-41. PMID 17608021 |
0.529 |
|
| 2007 |
Rai K, Chidester S, Zavala CV, Manos EJ, James SR, Karpf AR, Jones DA, Cairns BR. Dnmt2 functions in the cytoplasm to promote liver, brain, and retina development in zebrafish. Genes & Development. 21: 261-6. PMID 17289917 DOI: 10.1101/Gad.1472907 |
0.362 |
|
| 2007 |
Chung I, Karpf AR, Muindi JR, Conroy JM, Nowak NJ, Johnson CS, Trump DL. Epigenetic silencing of CYP24 in tumor-derived endothelial cells contributes to selective growth inhibition by calcitriol. The Journal of Biological Chemistry. 282: 8704-14. PMID 17244627 DOI: 10.1074/Jbc.M608894200 |
0.319 |
|
| 2006 |
Karpf AR. A potential role for epigenetic modulatory drugs in the enhancement of cancer/germ-line antigen vaccine efficacy. Epigenetics. 1: 116-20. PMID 17786175 |
0.454 |
|
| 2006 |
Morey SR, Smiraglia DJ, James SR, Yu J, Moser MT, Foster BA, Karpf AR. DNA methylation pathway alterations in an autochthonous murine model of prostate cancer. Cancer Research. 66: 11659-67. PMID 17178860 DOI: 10.1158/0008-5472.Can-06-1937 |
0.72 |
|
| 2006 |
Estève PO, Hang GC, Smallwood A, Feehery GR, Gangisetty O, Karpf AR, Carey MF, Pradhan S. Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication Genes and Development. 20: 3089-3103. PMID 17085482 DOI: 10.1101/gad.1463706 |
0.438 |
|
| 2006 |
Rai K, Nadauld LD, Chidester S, Manos EJ, James SR, Karpf AR, Cairns BR, Jones DA. Zebra fish Dnmt1 and Suv39h1 regulate organ-specific terminal differentiation during development. Molecular and Cellular Biology. 26: 7077-85. PMID 16980612 DOI: 10.1128/Mcb.00312-06 |
0.431 |
|
| 2006 |
James SR, Link PA, Karpf AR. Epigenetic regulation of X-linked cancer/germline antigen genes by DNMT1 and DNMT3b Oncogene. 25: 6975-6985. PMID 16715135 DOI: 10.1038/sj.onc.1209678 |
0.443 |
|
| 2006 |
Godert AM, Angelino N, Woloszynska-Read A, Morey SR, James SR, Karpf AR, Sufrin JR. An improved synthesis of psammaplin A. Bioorganic & Medicinal Chemistry Letters. 16: 3330-3. PMID 16632351 DOI: 10.1016/J.Bmcl.2006.03.008 |
0.733 |
|
| 2006 |
Luo W, Wang X, Kageshita T, Wakasugi S, Karpf AR, Ferrone S. Regulation of high molecular weight-melanoma associated antigen (HMW-MAA) gene expression by promoter DNA methylation in human melanoma cells. Oncogene. 25: 2873-84. PMID 16407841 DOI: 10.1038/Sj.Onc.1209319 |
0.522 |
|
| 2005 |
Karpf AR, Matsui S. Genetic disruption of cytosine DNA methyltransferase enzymes induces chromosomal instability in human cancer cells. Cancer Research. 65: 8635-9. PMID 16204030 DOI: 10.1158/0008-5472.CAN-05-1961 |
0.37 |
|
| 2005 |
Samlowski WE, Leachman SA, Wade M, Cassidy P, Porter-Gill P, Busby L, Wheeler R, Boucher K, Fitzpatrick F, Jones DA, Karpf AR. Evaluation of a 7-day continuous intravenous infusion of decitabine: inhibition of promoter-specific and global genomic DNA methylation. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 3897-905. PMID 15753459 DOI: 10.1200/Jco.2005.06.118 |
0.533 |
|
| 2005 |
Song L, James SR, Kazim L, Karpf AR. Specific method for the determination of genomic DNA methylation by liquid chromatography-electrospray ionization tandem mass spectrometry. Analytical Chemistry. 77: 504-10. PMID 15649046 DOI: 10.1021/ac0489420 |
0.429 |
|
| 2004 |
Karpf AR, Lasek AW, Ririe TO, Hanks AN, Grossman D, Jones DA. Limited gene activation in tumor and normal epithelial cells treated with the DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine. Molecular Pharmacology. 65: 18-27. PMID 14722233 DOI: 10.1124/Mol.65.1.18 |
0.428 |
|
| 2002 |
Karpf AR, Jones DA. Reactivating the expression of methylation silenced genes in human cancer. Oncogene. 21: 5496-503. PMID 12154410 DOI: 10.1038/sj.onc.1205602 |
0.586 |
|
| 2001 |
Karpf AR, Moore BC, Ririe TO, Jones DA. Activation of the p53 DNA Damage Response Pathway after Inhibition of DNA Methyltransferase by 5-Aza-2′-deoxycytidine Molecular Pharmacology. 59: 751-757. DOI: 10.1124/MOL.59.4.751 |
0.381 |
|
| 2000 |
Karpf AR, Peterson PW, Rawlins JT, Dalley BK, Yang Q, Albertsen H, Jones DA. Inhibition of DNA methyltransferase stimulates the expression of signal transducer and activator of transcription 1, 2, and 3 genes in colon tumor cells. Proceedings of the National Academy of Sciences of the United States of America. 96: 14007-12. PMID 10570189 DOI: 10.1073/PNAS.96.24.14007 |
0.383 |
|
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