| Year |
Citation |
Score |
| 2020 |
Yamamoto J, Suwa T, Murase Y, Tateno S, Mizutome H, Asatsuma-Okumura T, Shimizu N, Kishi T, Momose S, Kizaki M, Ito T, Yamaguchi Y, Handa H. ARID2 is a pomalidomide-dependent CRL4 substrate in multiple myeloma cells. Nature Chemical Biology. PMID 32958952 DOI: 10.1038/S41589-020-0645-3 |
0.309 |
|
| 2020 |
Tateno S, Iida M, Fujii S, Suwa T, Katayama M, Tokuyama H, Yamamoto J, Ito T, Sakamoto S, Handa H, Yamaguchi Y. Genome-wide screening reveals a role for subcellular localization of CRBN in the anti-myeloma activity of pomalidomide. Scientific Reports. 10: 4012. PMID 32132601 DOI: 10.1038/S41598-020-61027-W |
0.331 |
|
| 2019 |
Ando H, Sato T, Ito T, Yamamoto J, Sakamoto S, Nitta N, Asatsuma-Okumura T, Shimizu N, Mizushima R, Aoki I, Imai T, Yamaguchi Y, Berk AJ, Handa H. Cereblon Control of Zebrafish Brain Size by Regulation of Neural Stem Cell Proliferation. Iscience. 15: 95-108. PMID 31055217 DOI: 10.1016/J.Isci.2019.04.007 |
0.549 |
|
| 2017 |
Ito T, Handa H. Recent topics in IMiDs and cereblon. [Rinsho Ketsueki] the Japanese Journal of Clinical Hematology. 58: 2067-2073. PMID 28978850 DOI: 10.11406/Rinketsu.58.2067 |
0.305 |
|
| 2017 |
Boccitto M, Lee N, Sakamoto S, Spruce LA, Handa H, Clardy J, Seeholzer SH, Kalb RG. The Neuroprotective Marine Compound Psammaplysene A Binds the RNA-Binding Protein HNRNPK. Marine Drugs. 15. PMID 28783126 DOI: 10.3390/Md15080246 |
0.314 |
|
| 2017 |
Matyskiela M, Lu G, Ito T, Pagarigan B, Lu C, Miller K, Fang W, Wang N, Nguyen D, Houston J, Carmel G, Tran T, Riley M, Nosaka L, Lander G, ... ... Handa H, et al. Abstract SY37-02: Ligand-directed degradation of GSPT1 by a novel cereblon modulator drives potent antitumor effects Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Sy37-02 |
0.348 |
|
| 2016 |
Kabe Y, Yamamoto T, Kajimura M, Sugiura Y, Koike I, Ohmura M, Nakamura T, Tokumoto Y, Tsugawa H, Handa H, Kobayashi T, Suematsu M. Cystathionine beta-synthase and PGRMC1 as CO sensors. Free Radical Biology & Medicine. PMID 27565814 DOI: 10.1016/J.Freeradbiomed.2016.08.025 |
0.322 |
|
| 2016 |
Matyskiela ME, Lu G, Ito T, Pagarigan B, Lu CC, Miller K, Fang W, Wang NY, Nguyen D, Houston J, Carmel G, Tran T, Riley M, Nosaka L, Lander GC, ... ... Handa H, et al. A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase. Nature. PMID 27338790 DOI: 10.1038/Nature18611 |
0.325 |
|
| 2016 |
Nguyen TV, Lee JE, Sweredoski MJ, Yang SJ, Jeon SJ, Harrison JS, Yim JH, Lee SG, Handa H, Kuhlman B, Jeong JS, Reitsma JM, Park CS, Hess S, Deshaies RJ. Glutamine Triggers Acetylation-Dependent Degradation of Glutamine Synthetase via the Thalidomide Receptor Cereblon. Molecular Cell. 61: 809-820. PMID 26990986 DOI: 10.1016/J.Molcel.2016.02.032 |
0.318 |
|
| 2016 |
Harama D, Tamai M, Inukai T, Goi K, Yahata T, Ando K, Ito T, Handa H, Sugita K. Lenalidomide Effectively Induces Philadelphia-Chromosome Positive ALL Cells into Apoptosis in Synergy with Tyrosine Kinase Inhibitor Blood. 128: 1060-1060. DOI: 10.1182/Blood.V128.22.1060.1060 |
0.327 |
|
| 2015 |
Cao QF, Yamamoto J, Isobe T, Tateno S, Murase Y, Chen Y, Handa H, Yamaguchi Y. Characterization of the Human Transcription Elongation Factor Rtf1: Evidence for Non-overlapping Functions of Rtf1 and the Paf1 Complex. Molecular and Cellular Biology. PMID 26217014 DOI: 10.1128/Mcb.00601-15 |
0.383 |
|
| 2014 |
Yamamoto J, Hagiwara Y, Chiba K, Isobe T, Narita T, Handa H, Yamaguchi Y. DSIF and NELF interact with Integrator to specify the correct post-transcriptional fate of snRNA genes. Nature Communications. 5: 4263. PMID 24968874 DOI: 10.1038/Ncomms5263 |
0.363 |
|
| 2014 |
Takemoto M, Kawamura Y, Hirohama M, Yamaguchi Y, Handa H, Saitoh H, Nakao Y, Kawada M, Khalid K, Koshino H, Kimura K, Ito A, Yoshida M. Inhibition of protein SUMOylation by davidiin, an ellagitannin from Davidia involucrata. The Journal of Antibiotics. 67: 335-8. PMID 24424345 DOI: 10.1038/Ja.2013.142 |
0.309 |
|
| 2014 |
Gandhi AK, Kang J, Havens CG, Conklin T, Ning Y, Wu L, Ito T, Ando H, Waldman MF, Thakurta A, Klippel A, Handa H, Daniel TO, Schafer PH, Chopra R. Immunomodulatory agents lenalidomide and pomalidomide co-stimulate T cells by inducing degradation of T cell repressors Ikaros and Aiolos via modulation of the E3 ubiquitin ligase complex CRL4(CRBN.). British Journal of Haematology. 164: 811-21. PMID 24328678 DOI: 10.1111/Bjh.12708 |
0.335 |
|
| 2013 |
Miyazaki H, Higashimoto K, Yada Y, Endo TA, Sharif J, Komori T, Matsuda M, Koseki Y, Nakayama M, Soejima H, Handa H, Koseki H, Hirose S, Nishioka K. Ash1l methylates Lys36 of histone H3 independently of transcriptional elongation to counteract polycomb silencing. Plos Genetics. 9: e1003897. PMID 24244179 DOI: 10.1371/Journal.Pgen.1003897 |
0.34 |
|
| 2013 |
Ohno K, Sawada J, Takiya S, Kimoto M, Matsumoto A, Tsubota T, Uchino K, Hui CC, Sezutsu H, Handa H, Suzuki Y. Silk gland factor-2, involved in fibroin gene transcription, consists of LIM homeodomain, LIM-interacting, and single-stranded DNA-binding proteins. The Journal of Biological Chemistry. 288: 31581-91. PMID 24022586 DOI: 10.1074/Jbc.M113.514471 |
0.393 |
|
| 2013 |
Hotta K, Nashimoto A, Yasumura E, Suzuki M, Azuma M, Iizumi Y, Shima D, Nabeshima R, Hiramoto M, Okada A, Sakata-Sogawa K, Tokunaga M, Ito T, Ando H, Sakamoto S, ... ... Handa H, et al. Vesnarinone suppresses TNFα mRNA expression by inhibiting valosin-containing protein. Molecular Pharmacology. 83: 930-8. PMID 23393163 DOI: 10.1124/Mol.112.081935 |
0.306 |
|
| 2013 |
Yamaguchi Y, Shibata H, Handa H. Transcription elongation factors DSIF and NELF: promoter-proximal pausing and beyond. Biochimica Et Biophysica Acta. 1829: 98-104. PMID 23202475 DOI: 10.1016/J.Bbagrm.2012.11.007 |
0.353 |
|
| 2013 |
Umeda M, Uebi T, Maekawa N, Handa H, Imai T. PGJIFs, new mitochondrial PGJ2 target factors, regulate cell proliferation Journal of Biosciences and Medicines. 1: 11-15. DOI: 10.4236/Jbm.2013.13003 |
0.322 |
|
| 2013 |
Umeda M, Uebi T, Maekawa N, Masaike Y, Handa H, Imai T. Effective cofactor complex purification using nanobeads Journal of Biosciences and Medicines. 1: 5-10. DOI: 10.4236/Jbm.2013.13002 |
0.31 |
|
| 2013 |
Uebi T, Umeda M, Maekawa N, Karasawa S, Handa H, Imai T. Prohibitins, novel vitamin K2 target factors in osteoblast Journal of Biosciences and Medicines. 1: 1-4. DOI: 10.4236/Jbm.2013.13001 |
0.352 |
|
| 2012 |
Ito Y, Ito T, Karasawa S, Enomoto T, Nashimoto A, Hase Y, Sakamoto S, Mimori T, Matsumoto Y, Yamaguchi Y, Handa H. Identification of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) as a novel target of bisphenol A. Plos One. 7: e50481. PMID 23227178 DOI: 10.1371/Journal.Pone.0050481 |
0.308 |
|
| 2012 |
Lopez-Girona A, Mendy D, Ito T, Miller K, Gandhi AK, Kang J, Karasawa S, Carmel G, Jackson P, Abbasian M, Mahmoudi A, Cathers B, Rychak E, Gaidarova S, Chen R, ... ... Handa H, et al. Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide. Leukemia. 26: 2326-35. PMID 22552008 DOI: 10.1038/Leu.2012.119 |
0.359 |
|
| 2012 |
Ito T, Handa H. Deciphering the mystery of thalidomide teratogenicity. Congenital Anomalies. 52: 1-7. PMID 22348778 DOI: 10.1111/J.1741-4520.2011.00351.X |
0.319 |
|
| 2011 |
Enomoto T, Kukimoto I, Kawano MA, Yamaguchi Y, Berk AJ, Handa H. In vitro reconstitution of SV40 particles that are composed of VP1/2/3 capsid proteins and nucleosomal DNA and direct efficient gene transfer. Virology. 420: 1-9. PMID 21917285 DOI: 10.1016/J.Virol.2011.08.014 |
0.589 |
|
| 2011 |
Kitai Y, Fukuda H, Enomoto T, Asakawa Y, Suzuki T, Inouye S, Handa H. Cell selective targeting of a simian virus 40 virus-like particle conjugated to epidermal growth factor. Journal of Biotechnology. 155: 251-6. PMID 21745502 DOI: 10.1016/J.Jbiotec.2011.06.030 |
0.634 |
|
| 2011 |
Kawano A, Hayashi Y, Noguchi S, Handa H, Horikoshi M, Yamaguchi Y. Global analysis for functional residues of histone variant Htz1 using the comprehensive point mutant library. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 16: 590-607. PMID 21470346 DOI: 10.1111/J.1365-2443.2011.01512.X |
0.302 |
|
| 2011 |
Taneda T, Zhu W, Cao Q, Watanabe H, Yamaguchi Y, Handa H, Wada T. Erythropoiesis is regulated by the transcription elongation factor Foggy/Spt5 through gata1 gene regulation Genes to Cells. 16: 231-242. PMID 21205096 DOI: 10.1111/J.1365-2443.2010.01481.X |
0.361 |
|
| 2010 |
Kim S, Yamamoto J, Chen Y, Aida M, Wada T, Handa H, Yamaguchi Y. Evidence that cleavage factor Im is a heterotetrameric protein complex controlling alternative polyadenylation. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 15: 1003-13. PMID 20695905 DOI: 10.1111/J.1365-2443.2010.01436.X |
0.348 |
|
| 2010 |
Chiba K, Yamamoto J, Yamaguchi Y, Handa H. Promoter-proximal pausing and its release: molecular mechanisms and physiological functions. Experimental Cell Research. 316: 2723-30. PMID 20541545 DOI: 10.1016/J.Yexcr.2010.05.036 |
0.339 |
|
| 2010 |
Tominaga A, Sugawara H, Futagawa T, Inoue K, Sasaki K, Minamino N, Hatakeyama M, Handa H, Miyata A. Characterization of the testis-specific promoter region in the human pituitary adenylate cyclase-activating polypeptide (PACAP) gene. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 15: 595-606. PMID 20500521 DOI: 10.1111/J.1365-2443.2010.01403.X |
0.373 |
|
| 2010 |
Kume K, Iizumi Y, Shimada M, Ito Y, Kishi T, Yamaguchi Y, Handa H. Role of N-end rule ubiquitin ligases UBR1 and UBR2 in regulating the leucine-mTOR signaling pathway Genes to Cells. 15: 339-349. PMID 20298436 DOI: 10.1111/J.1365-2443.2010.01385.X |
0.333 |
|
| 2010 |
Ito T, Ando H, Suzuki T, Ogura T, Hotta K, Imamura Y, Yamaguchi Y, Handa H. Identification of a primary target of thalidomide teratogenicity. Science (New York, N.Y.). 327: 1345-50. PMID 20223979 DOI: 10.1126/Science.1177319 |
0.334 |
|
| 2009 |
Chen Y, Yamaguchi Y, Tsugeno Y, Yamamoto J, Yamada T, Nakamura M, Hisatake K, Handa H. DSIF, the Paf1 complex, and Tat-SF1 have nonredundant, cooperative roles in RNA polymerase II elongation. Genes & Development. 23: 2765-77. PMID 19952111 DOI: 10.1101/Gad.1834709 |
0.392 |
|
| 2009 |
Chen H, Contreras X, Yamaguchi Y, Handa H, Peterlin BM, Guo S. Repression of RNA polymerase II elongation in vivo is critically dependent on the C-terminus of Spt5. Plos One. 4: e6918. PMID 19742326 DOI: 10.1371/Journal.Pone.0006918 |
0.395 |
|
| 2009 |
Yung TM, Narita T, Komori T, Yamaguchi Y, Handa H. Cellular dynamics of the negative transcription elongation factor NELF. Experimental Cell Research. 315: 1693-705. PMID 19245807 DOI: 10.1016/J.Yexcr.2009.02.013 |
0.383 |
|
| 2009 |
Komori T, Inukai N, Yamada T, Yamaguchi Y, Handa H. Role of human transcription elongation factor DSIF in the suppression of senescence and apoptosis. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 14: 343-54. PMID 19210550 DOI: 10.1111/J.1365-2443.2008.01273.X |
0.388 |
|
| 2009 |
Kang J, Gemberling M, Nakamura M, Whitby FG, Handa H, Fairbrother WG, Tantin D. A general mechanism for transcription regulation by Oct1 and Oct4 in response to genotoxic and oxidative stress. Genes & Development. 23: 208-22. PMID 19171782 DOI: 10.1101/Gad.1750709 |
0.317 |
|
| 2009 |
Zou GM, Karikari C, Kabe Y, Handa H, Anders RA, Maitraz A. The Ape-1/Ref-1 redox antagonist E3330 inhibits the growth of tumor endothelium and endothelial progenitor cells: therapeutic implications in tumor angiogenesis Journal of Cellular Physiology. 219: 209-218. PMID 19097035 DOI: 10.1002/Jcp.21666 |
0.306 |
|
| 2008 |
Shimizu N, Yoshikawa N, Wada T, Handa H, Sano M, Fukuda K, Suematsu M, Sawai T, Morimoto C, Tanaka H. Tissue- and context-dependent modulation of hormonal sensitivity of glucocorticoid-responsive genes by hexamethylene bisacetamide-inducible protein 1 Molecular Endocrinology. 22: 2609-2623. PMID 18801933 DOI: 10.1210/Me.2008-0101 |
0.372 |
|
| 2008 |
Nakanishi A, Chapellier B, Maekawa N, Hiramoto M, Kuge T, Takahashi RU, Handa H, Imai T. SV40 vectors carrying minimal sequence of viral origin with exchangeable capsids. Virology. 379: 110-7. PMID 18667220 DOI: 10.1016/J.Virol.2008.06.032 |
0.309 |
|
| 2008 |
Takahashi Ru, Kanesashi Sn, Inoue T, Enomoto T, Kawano Ma, Tsukamoto H, Takeshita F, Imai T, Ochiya T, Kataoka K, Yamaguchi Y, Handa H. Presentation of functional foreign peptides on the surface of SV40 virus-like particles Journal of Biotechnology. 135: 385-392. PMID 18588926 DOI: 10.1016/J.Jbiotec.2008.05.012 |
0.306 |
|
| 2008 |
Ando K, Hirao S, Kabe Y, Ogura Y, Sato I, Yamaguchi Y, Wada T, Handa H. A new APE1/Ref-1-dependent pathway leading to reduction of NF-κB and AP-1, and activation of their DNA-binding activity Nucleic Acids Research. 36: 4327-4336. PMID 18586825 DOI: 10.1093/Nar/Gkn416 |
0.353 |
|
| 2008 |
Inoue T, Kawano Ma, Takahashi Ru, Tsukamoto H, Enomoto T, Imai T, Kataoka K, Handa H. Engineering of SV40-based nano-capsules for delivery of heterologous proteins as fusions with the minor capsid proteins VP2/3 Journal of Biotechnology. 134: 181-192. PMID 18243389 DOI: 10.1016/J.Jbiotec.2007.12.006 |
0.312 |
|
| 2008 |
Suzuki M, Furukawa S, Kuramori C, Sawa C, Kabe Y, Nakamura M, Sawada J, Yamaguchi Y, Sakamoto S, Inouye S, Handa H. Development of a chemical screening system using aqueorin-fused protein. Biochemical and Biophysical Research Communications. 368: 600-5. PMID 18243129 DOI: 10.1016/J.Bbrc.2008.01.107 |
0.617 |
|
| 2008 |
Yoshida M, Kabe Y, Wada T, Asai A, Handa H. A new mechanism of 6-((2-(dimethylamino)ethyl)amino)-3-hydroxy-7H-indeno(2, 1-c)quinolin-7-one dihydrochloride (TAS-103) action discovered by target screening with drug-immobilized affinity beads Molecular Pharmacology. 73: 987-994. PMID 18089836 DOI: 10.1124/Mol.107.043307 |
0.359 |
|
| 2008 |
Kuraoka I, Ito S, Wada T, Hayashida M, Lee L, Saijo M, Nakatsu Y, Matsumoto M, Matsunaga T, Handa H, Qin J, Nakatani Y, Tanaka K. Isolation of XAB2 complex involved in pre-mRNA splicing, transcription, and transcription-coupled repair Journal of Biological Chemistry. 283: 940-950. PMID 17981804 DOI: 10.1074/Jbc.M706647200 |
0.365 |
|
| 2007 |
Agawa Y, Sarhan M, Kageyama Y, Akagi K, Takai M, Hashiyama K, Wada T, Handa H, Iwamatsu A, Hirose S, Ueda H. Drosophila Blimp-1 is a transient transcriptional repressor that controls timing of the ecdysone-induced developmental pathway. Molecular and Cellular Biology. 27: 8739-47. PMID 17923694 DOI: 10.1128/Mcb.01304-07 |
0.313 |
|
| 2007 |
Yamaguchi Y, Mura T, Chanarat S, Okamoto S, Handa H. Hepatitis delta antigen binds to the clamp of RNA polymerase II and affects transcriptional fidelity Genes to Cells. 12: 863-875. PMID 17584298 DOI: 10.1111/J.1365-2443.2007.01094.X |
0.742 |
|
| 2007 |
Zhu W, Wada T, Okabe S, Taneda T, Yamaguchi Y, Handa H. DSIF contributes to transcriptional activation by DNA-binding activators by preventing pausing during transcription elongation Nucleic Acids Research. 35: 4064-4075. PMID 17567605 DOI: 10.1093/Nar/Gkm430 |
0.396 |
|
| 2007 |
Amir-Zilberstein L, Ainbinder E, Toube L, Yamaguchi Y, Handa H, Dikstein R. Differential regulation of NF-κB by elongation factors is determined by core promoter type Molecular and Cellular Biology. 27: 5246-5259. PMID 17502349 DOI: 10.1128/Mcb.00586-07 |
0.341 |
|
| 2007 |
Narita T, Yung TMC, Yamamoto J, Tsuboi Y, Tanabe H, Tanaka K, Yamaguchi Y, Handa H. NELF Interacts with CBC and Participates in 3′ End Processing of Replication-Dependent Histone mRNAs Molecular Cell. 26: 349-365. PMID 17499042 DOI: 10.1016/J.Molcel.2007.04.011 |
0.328 |
|
| 2007 |
Kuraoka I, Suzuki K, Ito S, Hayashida M, Kwei JSM, Ikegami T, Handa H, Nakabeppu Y, Tanaka K. RNA polymerase II bypasses 8-oxoguanine in the presence of transcription elongation factor TFIIS Dna Repair. 6: 841-851. PMID 17374514 DOI: 10.1016/J.Dnarep.2007.01.014 |
0.349 |
|
| 2007 |
Nakanishi A, Itoh N, Li PP, Handa H, Liddington RC, Kasamatsu H. Minor capsid proteins of simian virus 40 are dispensable for nucleocapsid assembly and cell entry but are required for nuclear entry of the viral genome. Journal of Virology. 81: 3778-85. PMID 17267496 DOI: 10.1128/Jvi.02664-06 |
0.306 |
|
| 2006 |
Yugami M, Kabe Y, Yamaguchi Y, Wada T, Handa H. hnRNP-U enhances the expression of specific genes by stabilizing mRNA. Febs Letters. 581: 1-7. PMID 17174306 DOI: 10.1016/J.Febslet.2006.11.062 |
0.32 |
|
| 2006 |
Yamamoto N, Suzuki M, Kawano MA, Inoue T, Takahashi RU, Tsukamoto H, Enomoto T, Yamaguchi Y, Wada T, Handa H. Adeno-associated virus site-specific integration is regulated by TRP-185. Journal of Virology. 81: 1990-2001. PMID 17151120 DOI: 10.1128/Jvi.02014-06 |
0.341 |
|
| 2006 |
Kubo T, Wada T, Yamaguchi Y, Shimizu A, Handa H. Knock-down of 25 kDa subunit of cleavage factor Im in Hela cells alters alternative polyadenylation within 3'-UTRs. Nucleic Acids Research. 34: 6264-71. PMID 17098938 DOI: 10.1093/Nar/Gkl794 |
0.315 |
|
| 2006 |
Uga H, Kuramori C, Ohta A, Tsuboi Y, Tanaka H, Hatakeyama M, Yamaguchi Y, Takahashi T, Kizaki M, Handa H. A New Mechanism of Methotrexate Action Revealed by Target Screening with Affinity Beads Molecular Pharmacology. 70: 1832-1839. PMID 16936229 DOI: 10.1124/Mol.106.025866 |
0.306 |
|
| 2006 |
Aida M, Chen Y, Nakajima K, Yamaguchi Y, Wada T, Handa H. Transcriptional pausing caused by NELF plays a dual role in regulating immediate-early expression of the junB gene. Molecular and Cellular Biology. 26: 6094-104. PMID 16880520 DOI: 10.1128/Mcb.02366-05 |
0.4 |
|
| 2006 |
Ogura Y, Azuma M, Tsuboi Y, Kabe Y, Yamaguchi Y, Wada T, Watanabe H, Handa H. TFII-I down-regulates a subset of estrogen-responsive genes through its interaction with an initiator element and estrogen receptor alpha. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 11: 373-81. PMID 16611241 DOI: 10.1111/J.1365-2443.2006.00952.X |
0.352 |
|
| 2006 |
Yamada T, Yamaguchi Y, Inukai N, Okamoto S, Mura T, Handa H. P-TEFb-mediated phosphorylation of hSpt5 C-terminal repeats is critical for processive transcription elongation. Molecular Cell. 21: 227-37. PMID 16427012 DOI: 10.1016/J.Molcel.2005.11.024 |
0.347 |
|
| 2005 |
Deléhouzée S, Yoshikawa T, Sawa C, Sawada J, Ito T, Omori M, Wada T, Yamaguchi Y, Kabe Y, Handa H. GABP, HCF-1 and YY1 are involved in Rb gene expression during myogenesis. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 10: 717-31. PMID 15966902 DOI: 10.1111/J.1365-2443.2005.00873.X |
0.348 |
|
| 2005 |
Shimizu N, Ouchida R, Yoshikawa N, Hisada T, Watanabe H, Okamoto K, Kusuhara M, Handa H, Morimoto C, Tanaka H. HEXIM1 forms a transcriptionally abortive complex with glucocorticoid receptor without involving 7SK RNA and positive transcription elongation factor b. Proceedings of the National Academy of Sciences of the United States of America. 102: 8555-60. PMID 15941832 DOI: 10.1073/Pnas.0409863102 |
0.392 |
|
| 2005 |
Wang G, Balamotis MA, Stevens JL, Yamaguchi Y, Handa H, Berk AJ. Mediator requirement for both recruitment and postrecruitment steps in transcription initiation. Molecular Cell. 17: 683-94. PMID 15749018 DOI: 10.1016/J.Molcel.2005.02.010 |
0.609 |
|
| 2005 |
Wu CH, Lee C, Fan R, Smith MJ, Yamaguchi Y, Handa H, Gilmour DS. Molecular characterization of Drosophila NELF. Nucleic Acids Research. 33: 1269-79. PMID 15741180 DOI: 10.1093/Nar/Gki274 |
0.346 |
|
| 2005 |
Kabe Y, Yamada J, Uga H, Yamaguchi Y, Wada T, Handa H. NF-Y is essential for the recruitment of RNA polymerase II and inducible transcription of several CCAAT box-containing genes. Molecular and Cellular Biology. 25: 512-22. PMID 15601870 DOI: 10.1128/Mcb.25.1.512-522.2005 |
0.366 |
|
| 2005 |
Parent M, Yung TM, Rancourt A, Ho EL, Vispé S, Suzuki-Matsuda F, Uehara A, Wada T, Handa H, Satoh MS. Poly(ADP-ribose) polymerase-1 is a negative regulator of HIV-1 transcription through competitive binding to TAR RNA with Tat.positive transcription elongation factor b (p-TEFb) complex. The Journal of Biological Chemistry. 280: 448-57. PMID 15498776 DOI: 10.1074/Jbc.M408435200 |
0.365 |
|
| 2005 |
Ando K, Shioda S, Handa H, Kataoka K. Isolation and characterization of an alternatively spliced variant of transcription factor Islet-1. Journal of Molecular Endocrinology. 31: 419-25. PMID 14664703 DOI: 10.1677/Jme.0.0310419 |
0.308 |
|
| 2004 |
Jennings BH, Shah S, Yamaguchi Y, Seki M, Phillips RG, Handa H, Ish-Horowicz D. Locus-specific requirements for Spt5 in transcriptional activation and repression in Drosophila. Current Biology : Cb. 14: 1680-4. PMID 15380072 DOI: 10.1016/J.Cub.2004.08.066 |
0.364 |
|
| 2004 |
Hatori H, Zenkoh T, Kobayashi M, Ohtsu Y, Shigematsu N, Setoi H, Hino M, Handa H. FR225659-binding proteins: identification as serine/threonine protein phosphatase PP1 and PP2A using high-performance affinity beads. The Journal of Antibiotics. 57: 456-61. PMID 15376558 DOI: 10.7164/Antibiotics.57.456 |
0.308 |
|
| 2004 |
Aiyar SE, Sun JL, Blair AL, Moskaluk CA, Lu YZ, Ye QN, Yamaguchi Y, Mukherjee A, Ren DM, Handa H, Li R. Attenuation of estrogen receptor alpha-mediated transcription through estrogen-stimulated recruitment of a negative elongation factor. Genes & Development. 18: 2134-46. PMID 15342491 DOI: 10.1101/Gad.1214104 |
0.382 |
|
| 2004 |
Mei Kwei JS, Kuraoka I, Horibata K, Ubukata M, Kobatake E, Iwai S, Handa H, Tanaka K. Blockage of RNA polymerase II at a cyclobutane pyrimidine dimer and 6-4 photoproduct. Biochemical and Biophysical Research Communications. 320: 1133-8. PMID 15249207 DOI: 10.1016/J.Bbrc.2004.06.066 |
0.337 |
|
| 2004 |
Oshima S, Nakamura T, Namiki S, Okada E, Tsuchiya K, Okamoto R, Yamazaki M, Yokota T, Aida M, Yamaguchi Y, Kanai T, Handa H, Watanabe M. Interferon regulatory factor 1 (IRF-1) and IRF-2 distinctively up-regulate gene expression and production of interleukin-7 in human intestinal epithelial cells. Molecular and Cellular Biology. 24: 6298-310. PMID 15226432 DOI: 10.1128/Mcb.24.14.6298-6310.2004 |
0.315 |
|
| 2004 |
Sawa C, Nedea E, Krogan N, Wada T, Handa H, Greenblatt J, Buratowski S. Bromodomain factor 1 (Bdf1) is phosphorylated by protein kinase CK2. Molecular and Cellular Biology. 24: 4734-42. PMID 15143168 DOI: 10.1128/Mcb.24.11.4734-4742.2004 |
0.693 |
|
| 2004 |
Mandal SS, Chu C, Wada T, Handa H, Shatkin AJ, Reinberg D. Functional interactions of RNA-capping enzyme with factors that positively and negatively regulate promoter escape by RNA polymerase II. Proceedings of the National Academy of Sciences of the United States of America. 101: 7572-7. PMID 15136722 DOI: 10.1073/Pnas.0401493101 |
0.376 |
|
| 2004 |
Endoh M, Zhu W, Hasegawa J, Watanabe H, Kim DK, Aida M, Inukai N, Narita T, Yamada T, Furuya A, Sato H, Yamaguchi Y, Mandal SS, Reinberg D, Wada T, ... Handa H, et al. Human Spt6 stimulates transcription elongation by RNA polymerase II in vitro. Molecular and Cellular Biology. 24: 3324-36. PMID 15060154 DOI: 10.1128/Mcb.24.8.3324-3336.2004 |
0.381 |
|
| 2004 |
Han SI, Kawano MA, Ishizu K, Watanabe H, Hasegawa M, Kanesashi SN, Kim YS, Nakanishi A, Kataoka K, Handa H. Rep68 protein of adeno-associated virus type 2 interacts with 14-3-3 proteins depending on phosphorylation at serine 535. Virology. 320: 144-55. PMID 15003870 DOI: 10.1016/J.Virol.2003.11.024 |
0.322 |
|
| 2004 |
Ainbinder E, Amir-Zilberstein L, Yamaguchi Y, Handa H, Dikstein R. Elongation inhibition by DRB sensitivity-inducing factor is regulated by the A20 promoter via a novel negative element and NF-kappaB. Molecular and Cellular Biology. 24: 2444-54. PMID 14993282 DOI: 10.1128/Mcb.24.6.2444-2454.2004 |
0.341 |
|
| 2004 |
Kataoka K, Shioda S, Ando K, Sakagami K, Handa H, Yasuda K. Differentially expressed Maf family transcription factors, c-Maf and MafA, activate glucagon and insulin gene expression in pancreatic islet alpha- and beta-cells. Journal of Molecular Endocrinology. 32: 9-20. PMID 14765989 DOI: 10.1677/Jme.0.0320009 |
0.331 |
|
| 2004 |
Inukai N, Yamaguchi Y, Kuraoka I, Yamada T, Kamijo S, Kato J, Tanaka K, Handa H. A novel hydrogen peroxide-induced phosphorylation and ubiquitination pathway leading to RNA polymerase II proteolysis. The Journal of Biological Chemistry. 279: 8190-5. PMID 14662762 DOI: 10.1074/Jbc.M311412200 |
0.321 |
|
| 2003 |
Nedialkov YA, Gong XQ, Yamaguchi Y, Handa H, Burton ZF. Assay of transient state kinetics of RNA polymerase II elongation. Methods in Enzymology. 371: 252-64. PMID 14712705 DOI: 10.1016/S0076-6879(03)71018-0 |
0.353 |
|
| 2003 |
Nakadai T, Shimada M, Shima D, Handa H, Tamura TA. Specific interaction with transcription factor IIA and localization of the mammalian TATA-binding protein-like protein (TLP/TRF2/TLF). The Journal of Biological Chemistry. 279: 7447-55. PMID 14570910 DOI: 10.1074/Jbc.M305412200 |
0.36 |
|
| 2003 |
Shimojima T, Okada M, Nakayama T, Ueda H, Okawa K, Iwamatsu A, Handa H, Hirose S. Drosophila FACT contributes to Hox gene expression through physical and functional interactions with GAGA factor. Genes & Development. 17: 1605-16. PMID 12815073 DOI: 10.1101/Gad.1086803 |
0.353 |
|
| 2003 |
Watanabe H, Suzuki A, Kobayashi M, Takahashi E, Itamoto M, Lubahn DB, Handa H, Iguchi T. Analysis of temporal changes in the expression of estrogen-regulated genes in the uterus Journal of Molecular Endocrinology. 30: 347-358. PMID 12790804 DOI: 10.1677/Jme.0.0300347 |
0.314 |
|
| 2003 |
Wu CH, Yamaguchi Y, Benjamin LR, Horvat-Gordon M, Washinsky J, Enerly E, Larsson J, Lambertsson A, Handa H, Gilmour D. NELF and DSIF cause promoter proximal pausing on the hsp70 promoter in Drosophila. Genes & Development. 17: 1402-14. PMID 12782658 DOI: 10.1101/Gad.1091403 |
0.347 |
|
| 2003 |
Hasegawa J, Endou M, Narita T, Yamada T, Yamaguchi Y, Wada T, Handa H. A rapid purification method for human RNA polymerase II by two-step affinity chromatography. Journal of Biochemistry. 133: 133-8. PMID 12761208 DOI: 10.1093/Jb/Mvg013 |
0.385 |
|
| 2003 |
Ohbayashi T, Shimada M, Nakadai T, Wada T, Handa H, Tamura T. Vertebrate TBP-like protein (TLP/TRF2/TLF) stimulates TATA-less terminal deoxynucleotidyl transferase promoters in a transient reporter assay, and TFIIA-binding capacity of TLP is required for this function. Nucleic Acids Research. 31: 2127-2133. PMID 12682363 DOI: 10.1093/Nar/Gkg315 |
0.395 |
|
| 2003 |
Kim DK, Inukai N, Yamada T, Furuya A, Sato H, Yamaguchi Y, Wada T, Handa H. Structure-function analysis of human Spt4: evidence that hSpt4 and hSpt5 exert their roles in transcriptional elongation as parts of the DSIF complex. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 8: 371-8. PMID 12653964 DOI: 10.1046/J.1365-2443.2003.00638.X |
0.385 |
|
| 2003 |
Nedialkov YA, Gong XQ, Hovde SL, Yamaguchi Y, Handa H, Geiger JH, Yan H, Burton ZF. NTP-driven translocation by human RNA polymerase II. The Journal of Biological Chemistry. 278: 18303-12. PMID 12637520 DOI: 10.1074/Jbc.M301103200 |
0.314 |
|
| 2003 |
Shima D, Yugami M, Tatsuno M, Wada T, Yamaguchi Y, Handa H. Mechanism of H-8 inhibition of cyclin-dependent kinase 9: Study using inhibitor-immobilized matrices Genes to Cells. 8: 215-223. PMID 12622719 DOI: 10.1046/J.1365-2443.2003.00627.X |
0.308 |
|
| 2003 |
Narita T, Yamaguchi Y, Yano K, Sugimoto S, Chanarat S, Wada T, Kim DK, Hasegawa J, Omori M, Inukai N, Endoh M, Yamada T, Handa H. Human transcription elongation factor NELF: identification of novel subunits and reconstitution of the functionally active complex. Molecular and Cellular Biology. 23: 1863-73. PMID 12612062 DOI: 10.1128/Mcb.23.6.1863-1873.2003 |
0.763 |
|
| 2003 |
Ouchida R, Kusuhara M, Shimizu N, Hisada T, Makino Y, Morimoto C, Handa H, Ohsuzu F, Tanaka H. Suppression of NF-kappaB-dependent gene expression by a hexamethylene bisacetamide-inducible protein HEXIM1 in human vascular smooth muscle cells. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 8: 95-107. PMID 12581153 DOI: 10.1046/J.1365-2443.2003.00618.X |
0.349 |
|
| 2002 |
Kuraoka I, Endou M, Yamaguchi Y, Wada T, Handa H, Tanaka K. Effects of endogenous DNA base lesions on transcription elongation by mammalian RNA polymerase II. Implications for transcription-coupled DNA repair and transcriptional mutagenesis. The Journal of Biological Chemistry. 278: 7294-9. PMID 12466278 DOI: 10.1074/Jbc.M208102200 |
0.342 |
|
| 2002 |
Kataoka K, Han SI, Shioda S, Hirai M, Nishizawa M, Handa H. MafA is a glucose-regulated and pancreatic beta-cell-specific transcriptional activator for the insulin gene. The Journal of Biological Chemistry. 277: 49903-10. PMID 12368292 DOI: 10.1074/Jbc.M206796200 |
0.328 |
|
| 2002 |
Yamaguchi Y, Deléhouzée S, Handa H. HIV and hepatitis delta virus: evolution takes different paths to relieve blocks in transcriptional elongation. Microbes and Infection. 4: 1169-75. PMID 12361917 DOI: 10.1016/S1286-4579(02)01641-6 |
0.345 |
|
| 2002 |
Nishi T, Shimizu N, Hiramoto M, Sato I, Yamaguchi Y, Hasegawa M, Aizawa S, Tanaka H, Kataoka K, Watanabe H, Handa H. Spatial redox regulation of a critical cysteine residue of NF-kappa B in vivo. The Journal of Biological Chemistry. 277: 44548-56. PMID 12213807 DOI: 10.1074/Jbc.M202970200 |
0.324 |
|
| 2002 |
Sawa C, Yoshikawa T, Matsuda-Suzuki F, Deléhouzée S, Goto M, Watanabe H, Sawada J, Kataoka K, Handa H. YEAF1/RYBP and YAF-2 are functionally distinct members of a cofactor family for the YY1 and E4TF1/hGABP transcription factors. The Journal of Biological Chemistry. 277: 22484-90. PMID 11953439 DOI: 10.1074/Jbc.M203060200 |
0.389 |
|
| 2002 |
Yamaguchi Y, Inukai N, Narita T, Wada T, Handa H. Evidence that negative elongation factor represses transcription elongation through binding to a DRB sensitivity-inducing factor/RNA polymerase II complex and RNA. Molecular and Cellular Biology. 22: 2918-27. PMID 11940650 DOI: 10.1128/Mcb.22.9.2918-2927.2002 |
0.396 |
|
| 2002 |
Tomohiro T, Sawada Ji J, Sawa C, Nakura H, Yoshida S, Kodaka M, Hatakeyama M, Kawaguchi H, Handa H, Okuno H. Total analysis and purification of cellular proteins binding to cisplatin-damaged DNA using submicron beads. Bioconjugate Chemistry. 13: 163-6. PMID 11906250 DOI: 10.1021/Bc015560H |
0.323 |
|
| 2001 |
Lavoie SB, Albert AL, Handa H, Vincent M, Bensaude O. The peptidyl-prolyl isomerase Pin1 interacts with hSpt5 phosphorylated by Cdk9. Journal of Molecular Biology. 312: 675-85. PMID 11575923 DOI: 10.1006/Jmbi.2001.4991 |
0.311 |
|
| 2001 |
Renner DB, Yamaguchi Y, Wada T, Handa H, Price DH. A highly purified RNA polymerase II elongation control system. The Journal of Biological Chemistry. 276: 42601-9. PMID 11553615 DOI: 10.1074/Jbc.M104967200 |
0.375 |
|
| 2001 |
Kataoka K, Shioda S, Yoshitomo-Nakagawa K, Handa H, Nishizawa M. Maf and Jun nuclear oncoproteins share downstream target genes for inducing cell transformation. The Journal of Biological Chemistry. 276: 36849-56. PMID 11461901 DOI: 10.1074/Jbc.M102234200 |
0.315 |
|
| 2001 |
Kataoka K, Handa H, Nishizawa M. Induction of cellular antioxidative stress genes through heterodimeric transcription factor Nrf2/small Maf by antirheumatic gold(I) compounds. The Journal of Biological Chemistry. 276: 34074-81. PMID 11429414 DOI: 10.1074/Jbc.M105383200 |
0.315 |
|
| 2001 |
Yamaguchi Y, Filipovska J, Yano K, Furuya A, Inukai N, Narita T, Wada T, Sugimoto S, Konarska MM, Handa H. Stimulation of RNA polymerase II elongation by hepatitis delta antigen. Science (New York, N.Y.). 293: 124-7. PMID 11387440 DOI: 10.1126/Science.1057925 |
0.646 |
|
| 2001 |
Morii E, Ogihara H, Oboki K, Sawa C, Sakuma T, Nomura S, Esko JD, Handa H, Kitamura Y. Inhibitory effect of the mi transcription factor encoded by the mutant mi allele on GA binding protein-mediated transcript expression in mouse mast cells Blood. 97: 3032-3039. PMID 11342428 DOI: 10.1182/Blood.V97.10.3032 |
0.367 |
|
| 2001 |
Yamaguchi Y, Narita T, Inukai N, Wada T, Handa H. SPT genes: key players in the regulation of transcription, chromatin structure and other cellular processes. Journal of Biochemistry. 129: 185-91. PMID 11173517 DOI: 10.1093/Oxfordjournals.Jbchem.A002842 |
0.339 |
|
| 2000 |
Guo S, Yamaguchi Y, Schilbach S, Wada T, Lee J, Goddard A, French D, Handa H, Rosenthal A. A regulator of transcriptional elongation controls vertebrate neuronal development Nature. 408: 366-369. PMID 11099044 DOI: 10.1038/35042590 |
0.313 |
|
| 2000 |
Yoshida N, Yoshida S, Araie M, Handa H, Nabeshima Y. Ets family transcription factor ESE-1 is expressed in corneal epithelial cells and is involved in their differentiation. Mechanisms of Development. 97: 27-34. PMID 11025204 DOI: 10.1016/S0925-4773(00)00419-6 |
0.342 |
|
| 2000 |
Wada T, Orphanides G, Hasegawa J, Kim DK, Shima D, Yamaguchi Y, Fukuda A, Hisatake K, Oh S, Reinberg D, Handa H. FACT relieves DSIF/NELF-mediated inhibition of transcriptional elongation and reveals functional differences between P-TEFb and TFIIH. Molecular Cell. 5: 1067-72. PMID 10912001 DOI: 10.1016/S1097-2765(00)80272-5 |
0.375 |
|
| 2000 |
Satoh S, Hirota M, Noguchi T, Hijikata M, Handa H, Shimotohno K. Cleavage of hepatitis C virus nonstructural protein 5A by a caspase-like protease(s) in mammalian cells. Virology. 270: 476-87. PMID 10793006 DOI: 10.1006/Viro.2000.0287 |
0.338 |
|
| 2000 |
Araki-Sasaki K, Aizawa S, Hiramoto M, Nakamura M, Iwase O, Nakata K, Sasaki Y, Mano T, Handa H, Tano Y. Substance P-induced cadherin expression and its signal transduction in a cloned human corneal epithelial cell line. Journal of Cellular Physiology. 182: 189-95. PMID 10623882 DOI: 10.1002/(Sici)1097-4652(200002)182:2<189::Aid-Jcp7>3.0.Co;2-9 |
0.302 |
|
| 1999 |
Sawada J, Simizu N, Suzuki F, Sawa C, Goto M, Hasegawa M, Imai T, Watanabe H, Handa H. Synergistic transcriptional activation by hGABP and select members of the activation transcription factor/cAMP response element-binding protein family. The Journal of Biological Chemistry. 274: 35475-82. PMID 10585419 DOI: 10.1074/Jbc.274.50.35475 |
0.381 |
|
| 1999 |
Kabe Y, Goto M, Shima D, Imai T, Wada T, Morohashi Ki, Shirakawa M, Hirose S, Handa H. The role of human MBF1 as a transcriptional coactivator. The Journal of Biological Chemistry. 274: 34196-202. PMID 10567391 DOI: 10.1074/Jbc.274.48.34196 |
0.388 |
|
| 1999 |
Ozaki J, Takemaru KI, Ikegami T, Mishima M, Ueda H, Hirose S, Kabe Y, Handa H, Shirakawa M. Identification of the core domain and the secondary structure of the transcriptional coactivator MBF1. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 4: 415-24. PMID 10469174 DOI: 10.1046/J.1365-2443.1999.00267.X |
0.353 |
|
| 1999 |
Kim JB, Yamaguchi Y, Wada T, Handa H, Sharp PA. Tat-SF1 protein associates with RAP30 and human SPT5 proteins. Molecular and Cellular Biology. 19: 5960-8. PMID 10454543 DOI: 10.1128/Mcb.19.9.5960 |
0.634 |
|
| 1999 |
Tsutsui H, Geltinger C, Murata T, Itakura K, Wada T, Handa H, Yokoyama KK. The DNA-binding and transcriptional activities of MAZ, a myc-associated zinc finger protein, are regulated by casein kinase II. Biochemical and Biophysical Research Communications. 262: 198-205. PMID 10448092 DOI: 10.1006/Bbrc.1999.1130 |
0.371 |
|
| 1999 |
Azuma N, Yamaguchi Y, Handa H, Hayakawa M, Kanai A, Yamada M. Missense mutation in the alternative splice region of the PAX6 gene in eye anomalies American Journal of Human Genetics. 65: 656-663. PMID 10441571 DOI: 10.1086/302529 |
0.325 |
|
| 1999 |
Hoque M, Ishizu K, Matsumoto A, Han SI, Arisaka F, Takayama M, Suzuki K, Kato K, Kanda T, Watanabe H, Handa H. Nuclear transport of the major capsid protein is essential for adeno-associated virus capsid formation. Journal of Virology. 73: 7912-5. PMID 10438891 DOI: 10.1128/Jvi.73.9.7912-7915.1999 |
0.301 |
|
| 1999 |
Yamaguchi Y, Takagi T, Wada T, Yano K, Furuya A, Sugimoto S, Hasegawa J, Handa H. NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation. Cell. 97: 41-51. PMID 10199401 DOI: 10.1016/S0092-8674(00)80713-8 |
0.361 |
|
| 1999 |
Yamaguchi Y, Wada T, Watanabe D, Takagi T, Hasegawa J, Handa H. Structure and function of the human transcription elongation factor DSIF. The Journal of Biological Chemistry. 274: 8085-92. PMID 10075709 DOI: 10.1074/Jbc.274.12.8085 |
0.376 |
|
| 1999 |
Wada T, Takagi T, Yamaguchi Y, Watanabe D, Handa H. Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro. The Embo Journal. 17: 7395-403. PMID 9857195 DOI: 10.1093/Emboj/17.24.7395 |
0.361 |
|
| 1998 |
Suzuki F, Goto M, Sawa C, Ito S, Watanabe H, Sawada J, Handa H. Functional interactions of transcription factor human GA-binding protein subunits. The Journal of Biological Chemistry. 273: 29302-8. PMID 9792629 DOI: 10.1074/Jbc.273.45.29302 |
0.367 |
|
| 1998 |
Yamaguchi Y, Wada T, Suzuki F, Takagi T, Hasegawa J, Handa H. Casein kinase II interacts with the bZIP domains of several transcription factors. Nucleic Acids Research. 26: 3854-61. PMID 9685505 DOI: 10.1093/Nar/26.16.3854 |
0.363 |
|
| 1998 |
Yamaguchi Y, Wada T, Handa H. Interplay between positive and negative elongation factors: drawing a new view of DRB. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 3: 9-15. PMID 9581978 DOI: 10.1046/J.1365-2443.1998.00162.X |
0.347 |
|
| 1998 |
Vassias I, Hazan U, Michel Y, Sawa C, Handa H, Gouya L, Morinet F. Regulation of human B19 parvovirus promoter expression by hGABP (E4TF1) transcription factor. The Journal of Biological Chemistry. 273: 8287-93. PMID 9525935 DOI: 10.1074/Jbc.273.14.8287 |
0.381 |
|
| 1998 |
Hirano F, Tanaka H, Hirano Y, Hiramoto M, Handa H, Makino I, Scheidereit C. Functional interference of Sp1 and NF-kappaB through the same DNA binding site. Molecular and Cellular Biology. 18: 1266-74. PMID 9488441 DOI: 10.1128/Mcb.18.3.1266 |
0.322 |
|
| 1998 |
Hartzog GA, Wada T, Handa H, Winston F. Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae Genes and Development. 12: 357-369. PMID 9450930 DOI: 10.1101/Gad.12.3.357 |
0.375 |
|
| 1998 |
Wada T, Takagi T, Yamaguchi Y, Ferdous A, Imai T, Hirose S, Sugimoto S, Yano K, Hartzog GA, Winston F, Buratowski S, Handa H. DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs. Genes & Development. 12: 343-56. PMID 9450929 DOI: 10.1101/Gad.12.3.343 |
0.723 |
|
| 1998 |
Nakade K, Handa H, Nagata K. Promoter structure of the MxA gene that confers resistance to influenza virus. Febs Letters. 418: 315-8. PMID 9428735 DOI: 10.1016/S0014-5793(97)01372-0 |
0.347 |
|
| 1998 |
van Dijk TB, Baltus B, Caldenhoven E, Handa H, Raaijmakers JA, Lammers JJ, Koenderman L, de Groot RP. Cloning and Characterization of the Human Interleukin-3 (IL-3)/IL-5/ Granulocyte-Macrophage Colony-Stimulating Factor Receptor βc Gene: Regulation by Ets Family Members Blood. 92: 3636-3646. DOI: 10.1182/Blood.V92.10.3636 |
0.307 |
|
| 1998 |
Kaizawa M, Watanabe S, Nobukuni T, Horikoshi M, Handa H, Kuchino Y, Sekiya T, Mizushima H. Maintenance of Transcription Factor DataBase TFDB by TFDB Maintenance System Genome Informatics. 9: 316-318. DOI: 10.11234/Gi1990.9.316 |
0.314 |
|
| 1997 |
Yamaguchi Y, Sawada J, Yamada M, Handa H, Azuma N. Autoregulation of Pax6 transcriptional activation by two distinct DNA-binding subdomains of the paired domain. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 2: 255-61. PMID 9224659 DOI: 10.1046/J.1365-2443.1997.1170315.X |
0.323 |
|
| 1997 |
Aoki H, Seki T, Sawada J, Handa H, Adachi K. The promoter of an androgen dependent gene in the hamster flank organ. Journal of Dermatological Science. 15: 36-43. PMID 9186810 DOI: 10.1016/S0923-1811(97)00597-5 |
0.35 |
|
| 1997 |
Imai T, Matsuda K, Shimojima T, Hashimoto T, Masuhiro Y, Kitamoto T, Sugita A, Suzuki K, Matsumoto H, Masushige S, Nogi Y, Muramatsu M, Handa H, Kato S. ERC-55, a binding protein for the papilloma virus E6 oncoprotein, specifically interacts with vitamin D receptor among nuclear receptors. Biochemical and Biophysical Research Communications. 233: 765-9. PMID 9168930 DOI: 10.1006/Bbrc.1997.6531 |
0.355 |
|
| 1997 |
Li FQ, Takemaru K, Goto M, Ueda H, Handa H, Hirose S. Transcriptional activation through interaction of MBF2 with TFIIA. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 2: 143-53. PMID 9167971 DOI: 10.1046/J.1365-2443.1997.1090306.X |
0.304 |
|
| 1997 |
Momose F, Handa H, Nagata K. Identification of host factors that regulate the influenza virus RNA polymerase activity. Biochimie. 78: 1103-8. PMID 9150891 DOI: 10.1016/S0300-9084(97)86736-3 |
0.33 |
|
| 1997 |
Kamura T, Handa H, Hamasaki N, Kitajima S. Characterization of the human thrombopoietin gene promoter. A possible role of an Ets transcription factor, E4TF1/GABP. The Journal of Biological Chemistry. 272: 11361-8. PMID 9111044 DOI: 10.1074/Jbc.272.17.11361 |
0.383 |
|
| 1997 |
Kawase H, Okuwaki M, Miyaji M, Ohba R, Handa H, Ishimi Y, Fujii-Nakata T, Kikuchi A, Nagata K. NAP-I is a functional homologue of TAF-I that is required for replication and transcription of the adenovirus genome in a chromatin-like structure. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 1: 1045-56. PMID 9077453 DOI: 10.1046/J.1365-2443.1996.D01-223.X |
0.329 |
|
| 1997 |
Hatakeyama M, Ogura Y, Sawada J, Fujimoto K, Handa H, Kawaguchi H. Preparation of dimerized polypeptide-carrying microspheres and purification of specific proteins bound to these microspheres Colloids and Surfaces B: Biointerfaces. 10: 41-49. DOI: 10.1016/S0927-7765(97)00042-8 |
0.304 |
|
| 1996 |
Sawa C, Goto M, Suzuki F, Watanabe H, Sawada J, Handa H. Functional domains of transcription factor hGABP beta1/E4TF1-53 required for nuclear localization and transcription activation. Nucleic Acids Research. 24: 4954-61. PMID 9016666 DOI: 10.1093/Nar/24.24.4954 |
0.313 |
|
| 1996 |
Yajima H, Kosukegawa A, Hoque MM, Shimojima T, Ishizu K, Takayama M, Sasaki Y, Sakai H, Otsuka M, Inokuchi S, Handa H. Construction and characterization of a recombinant adenovirus vector carrying the human preproinsulin gene under the control of the metallothionein gene promoter. Biochemical and Biophysical Research Communications. 229: 778-87. PMID 8954972 DOI: 10.1006/Bbrc.1996.1880 |
0.303 |
|
| 1996 |
Shimada H, Wada T, Handa H, Ohta H, Mizoguchi H, Nishimura K, Masuda T, Shioi Y, Takamiya K. A transcription factor with a leucine-zipper motif involved in light-dependent inhibition of expression of the puf operon in the photosynthetic bacterium Rhodobacter sphaeroides. Plant & Cell Physiology. 37: 515-22. PMID 8759915 DOI: 10.1093/Oxfordjournals.Pcp.A028974 |
0.35 |
|
| 1996 |
Hirano F, Tanada H, Makino Y, Okamoto K, Hiramoto M, Handa H, Makino I. Induction of the transcription factor AP-1 in cultured human colon adenocarcinoma cells following exposure to bile acids. Carcinogenesis. 17: 427-33. PMID 8631127 DOI: 10.1093/Carcin/17.3.427 |
0.341 |
|
| 1996 |
Wada T, Takagi T, Yamaguchi Y, Kawase H, Hiramoto M, Ferdous A, Takayama M, Lee KA, Hurst HC, Handa H. Copurification of casein kinase II with transcription factor ATF/E4TF3. Nucleic Acids Research. 24: 876-84. PMID 8600455 DOI: 10.1093/Nar/24.5.876 |
0.359 |
|
| 1996 |
Wada T, Watanabe H, Kawaguchi H, Handa H. DNA affinity chromatography. Methods in Enzymology. 254: 595-604. PMID 8531717 DOI: 10.1016/0076-6879(95)54042-3 |
0.313 |
|
| 1996 |
Watanabe K, Handa H, Mizumoto K, Nagata K. Mechanism for inhibition of influenza virus RNA polymerase activity by matrix protein. Journal of Virology. 70: 241-7. PMID 8523532 DOI: 10.1128/Jvi.70.1.241-247.1996 |
0.304 |
|
| 1995 |
Shimizu K, Handa H, Nakada S, Nagata K. Regulation of influenza virus RNA polymerase activity by cellular and viral factors. Nucleic Acids Research. 22: 5047-53. PMID 7800498 DOI: 10.1093/Nar/22.23.5047 |
0.329 |
|
| 1995 |
Nagata K, Kawase H, Handa H, Yano K, Yamasaki M, Ishimi Y, Okuda A, Kikuchi A, Matsumoto K. Replication factor encoded by a putative oncogene, set, associated with myeloid leukemogenesis. Proceedings of the National Academy of Sciences of the United States of America. 92: 4279-83. PMID 7753797 DOI: 10.1073/Pnas.92.10.4279 |
0.348 |
|
| 1995 |
Matsumoto K, Okuwaki M, Kawase H, Handa H, Hanaoka F, Nagata K. Stimulation of DNA transcription by the replication factor from the adenovirus genome in a chromatin-like structure. The Journal of Biological Chemistry. 270: 9645-50. PMID 7721897 DOI: 10.1074/Jbc.270.16.9645 |
0.35 |
|
| 1995 |
Mach V, Takiya S, Ohno K, Handa H, Imai T, Suzuki Y. Silk gland factor-1 involved in the regulation of Bombyx sericin-1 gene contains fork head motif. The Journal of Biological Chemistry. 270: 9340-6. PMID 7721856 DOI: 10.1074/Jbc.270.16.9340 |
0.365 |
|
| 1995 |
Rosmarin AG, Caprio DG, Kirsch DG, Handa H, Simkevich CP. GABP and PU.1 compete for binding, yet cooperate to increase CD18 (beta 2 leukocyte integrin) transcription. The Journal of Biological Chemistry. 270: 23627-33. PMID 7559529 DOI: 10.1074/Jbc.270.40.23627 |
0.304 |
|
| 1994 |
Inomata Y, Wada T, Handa H, Fujimoto K, Kawaguchi H. Preparation of DNA-carrying affinity latex and purification of transcription factors with the latex Journal of Biomaterials Science-Polymer Edition. 5: 293-302. PMID 8025028 DOI: 10.1163/156856294X00031 |
0.304 |
|
| 1994 |
Sawada J, Goto M, Sawa C, Watanabe H, Handa H. Transcriptional activation through the tetrameric complex formation of E4TF1 subunits. The Embo Journal. 13: 1396-1402. DOI: 10.1002/J.1460-2075.1994.Tb06393.X |
0.359 |
|
| 1993 |
Tabuchi H, Handa H, Hirose S. Underwinding of DNA on binding of yeast TFIID to the TATA element Biochemical and Biophysical Research Communications. 192: 1432-1438. PMID 8507207 DOI: 10.1006/Bbrc.1993.1576 |
0.356 |
|
| 1993 |
Watanabe H, Sawada J, Yano K, Yamaguchi K, Goto M, Handa H. cDNA cloning of transcription factor E4TF1 subunits with Ets and notch motifs. Molecular and Cellular Biology. 13: 1385-91. PMID 8441384 DOI: 10.1128/Mcb.13.3.1385 |
0.351 |
|
| 1992 |
Inomata Y, Kawaguchi H, Hiramoto M, Wada T, Handa H. Direct purification of multiple ATF/E4TF3 polypeptides from HeLa cell crude nuclear extracts using DNA affinity latex particles. Analytical Biochemistry. 206: 109-14. PMID 1456421 DOI: 10.1016/S0003-2697(05)80018-1 |
0.336 |
|
| 1991 |
Usuda Y, Kubota A, Berk AJ, Handa H. Affinity purification of transcription factor IIA from HeLa cell nuclear extracts Embo Journal. 10: 2305-2310. PMID 2065666 DOI: 10.1002/J.1460-2075.1991.Tb07767.X |
0.61 |
|
| 1991 |
Mizutani M, Ohta T, Watanabe H, Handa H, Hirose S. Negative supercoiling of DNA facilitates an interaction between transcription factor IID and the fibroin gene promoter. Proceedings of the National Academy of Sciences of the United States of America. 88: 718-22. PMID 1992462 DOI: 10.1073/Pnas.88.3.718 |
0.381 |
|
| 1991 |
Wada T, Watanabe H, Usuda Y, Handa H. Different biological activities of the hetero- and homodimers formed by the 47- and 43-kilodalton proteins of transcription factor ATF/E4TF3. Journal of Virology. 65: 557-64. PMID 1987369 DOI: 10.1128/Jvi.65.2.557-564.1991 |
0.394 |
|
| 1991 |
Imai T, Kawaguchi H, Wada T, Handa H. E1A gene products stimulate in vitro transcription from the adenovirus early region 4 promoter by enhancing a stable preinitiation complex. Virus Genes. 5: 47-55. PMID 1826802 DOI: 10.1007/Bf00571730 |
0.356 |
|
| 1991 |
INOMATA Y, KAWAGUCHI H, WADA T, HANDA H. Improvement of DNA Immobilized Latex for the Purification of Transcription Factors. Kobunshi Ronbunshu. 48: 335-340. DOI: 10.1295/Koron.48.335 |
0.323 |
|
| 1990 |
Watanabe H, Wada T, Handa H. Transcription factor E4TF1 contains two subunits with different functions. The Embo Journal. 9: 841-847. DOI: 10.1002/J.1460-2075.1990.Tb08181.X |
0.391 |
|
| 1989 |
Kawaguchi H, Asai A, Ohtsuka Y, Watanabe H, Wada T, Handa H. Purification of DNA-binding transcription factors by their selective adsorption on the affinity latex particles. Nucleic Acids Research. 17: 6229-40. PMID 2771645 DOI: 10.1093/Nar/17.15.6229 |
0.325 |
|
| 1989 |
Handa H, Watanabe H, Suzuki Y, Hirose S. Effect of DNA supercoiling on in vitro transcription from the adenovirus early region 4. Febs Letters. 249: 17-20. PMID 2721686 DOI: 10.1016/0014-5793(89)80006-7 |
0.34 |
|
| 1989 |
Sogawa K, Handa H, Fujisawa-Sehara A, Hiromasa T, Yamane M, Fujii-Kuriyama Y. Repression of cytochrome P-450c gene expression by cotransfection with adenovirus E1a DNA. European Journal of Biochemistry. 181: 539-44. PMID 2525087 DOI: 10.1111/J.1432-1033.1989.Tb14757.X |
0.329 |
|
| 1989 |
Ooyama S, Imai T, Hanaka S, Handa H. Transcription in the reverse orientation at either terminus of the adenovirus type 5 genome. The Embo Journal. 8: 863-868. DOI: 10.1002/J.1460-2075.1989.Tb03447.X |
0.342 |
|
| 1988 |
Watanabe H, Imai T, Sharp PA, Handa H. Identification of two transcription factors that bind to specific elements in the promoter of the adenovirus early-region 4. Molecular and Cellular Biology. 8: 1290-300. PMID 3367909 DOI: 10.1128/Mcb.8.3.1290 |
0.526 |
|
| 1988 |
Akahori Y, Handa H, Imai K, Abe M, Kameyama K, Hibiya M, Yasui H, Okamura K, Naito M, Matsuoka H. Sigma region located between C mu and C delta genes of human immunoglobulin heavy chain: possible involvement of tRNA-like structure in RNA splicing. Nucleic Acids Research. 16: 9497-511. PMID 3141902 DOI: 10.1093/Nar/16.20.9497 |
0.306 |
|
| 1988 |
Nishigaki T, Hanaka S, Kingston RE, Handa H. A specific domain of the adenovirus EIV promoter is necessary to maintain susceptibility of the integrated promoter to EIA transactivation Molecular and Cellular Biology. 8: 353-360. PMID 2961981 DOI: 10.1128/Mcb.8.1.353 |
0.55 |
|
| 1988 |
Abe A, Wada T, Handa H, Nogi Y, Fukasawa T. Efficient Usage of a Galactose-inducible Expression Vector for the Production of Heterologous Protein in Yeast Agricultural and Biological Chemistry. 52: 2035-2041. DOI: 10.1271/Bbb1961.52.2035 |
0.32 |
|
| 1987 |
Hanaka S, Nishigaki T, Sharp PA, Handa H. Regulation of in vitro and in vivo transcription of early-region IV of adenovirus type 5 by multiple cis-acting elements. Molecular and Cellular Biology. 7: 2578-87. PMID 3614200 DOI: 10.1128/Mcb.7.7.2578 |
0.531 |
|
| 1986 |
Oda K, Masuda-Murata M, Shiroki K, Handa H. Mitogenic activity of the adenovirus type 12 E1A gene induced by hormones in rat cells. Journal of Virology. 58: 125-33. PMID 2936902 DOI: 10.1128/Jvi.58.1.125-133.1986 |
0.347 |
|
| 1984 |
Handa H, Sharp PA. Requirement for distal upstream sequences for maximal transcription in vitro of early region IV of adenovirus. Molecular and Cellular Biology. 4: 791-8. PMID 6717442 DOI: 10.1128/Mcb.4.4.791 |
0.52 |
|
| 1983 |
Notake M, Kurosaki T, Yamamoto T, Handa H, Mishina M, Numa S. Sequence requirement for transcription in vitro of the human corticotropin/beta-lipotropin precursor gene. European Journal of Biochemistry / Febs. 133: 599-605. PMID 6305652 DOI: 10.1111/J.1432-1033.1983.Tb07504.X |
0.361 |
|
| 1983 |
Handa H, Kingston RE, Sharp PA. Inhibition of adenovirus early region IV transcription in vitro by a purified viral DNA binding protein. Nature. 302: 545-7. PMID 6300688 DOI: 10.1038/302545A0 |
0.664 |
|
| 1981 |
Cepko CL, Hansen U, Handa H, Sharp PA. Sequential transcription-translation of simian virus 40 by using mammalian cell extracts. Molecular and Cellular Biology. 1: 919-31. PMID 6287212 DOI: 10.1128/Mcb.1.10.919 |
0.644 |
|
| 1981 |
Handa H, Kaufman RJ, Manley J, Gefter M, Sharp PA. Transcription of Simian virus 40 DNA in a HeLa whole cell extract. The Journal of Biological Chemistry. 256: 478-82. PMID 6256354 |
0.579 |
|
| 1980 |
Handa H, Sharp PA. Expression of early and late simian virus 40 transcripts in the absence of protein synthesis. Journal of Virology. 34: 592-7. PMID 6247498 DOI: 10.1128/Jvi.34.3.592-597.1980 |
0.495 |
|
| 1977 |
Shiroki K, Handa H, Shimojo H, Yano S, Ojima S, Fujinaga K. Establishment and characterization of rat cell lines transformed by restriction endonuclease fragments of adenovirus 12 DNA. Virology. 82: 462-71. PMID 919348 DOI: 10.1016/0042-6822(77)90019-8 |
0.302 |
|
| 1977 |
Handa H, Shiroki K, Shimojo H. Establishment and characterization of KB cell lines latently infected with adeno-associated virus type 1. Virology. 82: 84-92. PMID 898681 DOI: 10.1016/0042-6822(77)90034-4 |
0.301 |
|
| 1976 |
Handa H, Shimojo H, Yamaguchi K. Multiplication of adeno-associated virus type 1 in cells coinfected with a temperature-sensitive mutant of human adenovirus type 31. Virology. 74: 1-15. PMID 982809 DOI: 10.1016/0042-6822(76)90123-9 |
0.313 |
|
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