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Franklin W. Huang, Ph.D. - Publications

Affiliations: 
2007 Harvard University, Cambridge, MA, United States 
Area:
Molecular Biology, Genetics
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27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Zhao SG, Chen WS, Li H, Foye A, Zhang M, Sjöström M, Aggarwal R, Playdle D, Liao A, Alumkal JJ, Das R, Chou J, Hua JT, Barnard TJ, Bailey AM, ... ... Huang FW, et al. The DNA methylation landscape of advanced prostate cancer. Nature Genetics. PMID 32661416 DOI: 10.1038/S41588-020-0648-8  0.352
2020 Song H, Seddighzadeh B, Cooperberg MR, Huang FW. Expression of ACE2, the SARS-CoV-2 Receptor, and TMPRSS2 in Prostate Epithelial Cells. European Urology. PMID 32418620 DOI: 10.1016/J.Eururo.2020.04.065  0.324
2020 Stern JL, Hibshman G, Hu K, Ferrara SE, Costello JC, Kim W, Tamayo P, Cech TR, Huang FW. Mesenchymal and MAPK Expression Signatures Associate with Telomerase Promoter Mutations in Multiple Cancers. Molecular Cancer Research : McR. PMID 32276990 DOI: 10.1158/1541-7786.Mcr-19-1244  0.442
2020 Kwon D, Wright F, Zhang L, Chou J, Borno H, Desai A, Oh DY, Pollock YG, Bose R, Huang FW, Hope T, Friedlander TW, Fong L, Feng FY, Small EJ, et al. Treatment outcomes in metastatic prostate cancer patients with DNA damage repair mutations. Journal of Clinical Oncology. 38: 187-187. DOI: 10.1200/Jco.2020.38.6_Suppl.187  0.308
2020 Kim E, Koga Y, Carrot-Zhang J, Campbell JD, Huang F. Abstract A122: Comparison of mutational profiles in primary prostate cancers between men with African and European ancestry Cancer Epidemiology, Biomarkers & Prevention. DOI: 10.1158/1538-7755.Disp18-A122  0.329
2019 Ghandi M, Huang FW, Jané-Valbuena J, Kryukov GV, Lo CC, McDonald ER, Barretina J, Gelfand ET, Bielski CM, Li H, Hu K, Andreev-Drakhlin AY, Kim J, Hess JM, Haas BJ, et al. Next-generation characterization of the Cancer Cell Line Encyclopedia. Nature. PMID 31068700 DOI: 10.1038/S41586-019-1186-3  0.316
2018 Huang FW. Towards Greater Inclusion in Cancer Genomics Studies. Cancer Research. 78: 6726-6727. PMID 30552120 DOI: 10.1158/0008-5472.Can-18-3382  0.325
2018 Armenia J, Wankowicz SAM, Liu D, Gao J, Kundra R, Reznik E, Chatila WK, Chakravarty D, Han GC, Coleman I, Montgomery B, Pritchard C, Morrissey C, Barbieri CE, Beltran H, ... ... Huang FW, et al. The long tail of oncogenic drivers in prostate cancer. Nature Genetics. PMID 29610475 DOI: 10.1038/S41588-018-0078-Z  0.39
2017 Stern JL, Paucek RD, Huang FW, Ghandi M, Nwumeh R, Costello JC, Cech TR. Allele-Specific DNA Methylation and Its Interplay with Repressive Histone Marks at Promoter-Mutant TERT Genes. Cell Reports. 21: 3700-3707. PMID 29281820 DOI: 10.1016/J.Celrep.2017.12.001  0.329
2017 Dhingra P, Martinez-Fundichely A, Berger A, Huang FW, Forbes AN, Liu EM, Liu D, Sboner A, Tamayo P, Rickman DS, Rubin MA, Khurana E. Identification of novel prostate cancer drivers using RegNetDriver: a framework for integration of genetic and epigenetic alterations with tissue-specific regulatory network. Genome Biology. 18: 141. PMID 28750683 DOI: 10.1186/S13059-017-1266-3  0.32
2017 Huang FW, Mosquera JM, Garofalo A, Oh C, Baco M, Amin-Mansour A, Rabasha B, Bahl S, Mullane SA, Robinson BD, Aldubayan S, Khani F, Karir B, Kim E, Chimene-Weiss J, et al. Exome Sequencing of African-American Prostate Cancer Reveals Loss-of-Function ERF Mutations. Cancer Discovery. PMID 28515055 DOI: 10.1158/2159-8290.Cd-16-0960  0.378
2017 Huang FW, Rinne ML, Lundgren KT, Mullane SA, Moreno I, Reed S, Gydush G, Adalsteinsson V, Novak J, Hahn WC, Signoretti S, Choueiri TK, Garraway LA, Bellmunt J. Cell-free tumor DNA and TERT promoter mutations in bladder cancer. Journal of Clinical Oncology. 35: 353-353. DOI: 10.1200/Jco.2017.35.6_Suppl.353  0.328
2017 Armenia J, Mullane SA, Gao J, Chakravarty D, Kundra R, Huang FW, Han GC, Robinson D, Garraway LA, Nelson P, Rubin MA, Taplin M, Abida W, Sawyers CL, Chinnaiyan AM, et al. The long tail of significantly mutated genes in prostate cancer. Journal of Clinical Oncology. 35: 131-131. DOI: 10.1200/Jco.2017.35.6_Suppl.131  0.399
2017 Armenia J, Mullane S, Gao J, Chakravarty D, Kundra R, Huang F, Han C, Robinson D, Garraway LA, Nelson P, Rubin M, Taplin M, Abida W, Sawyers CL, Chinnaiyan AM, et al. Abstract 3566: The long tail of significantly mutated genes in prostate cancer Cancer Research. 77: 3566-3566. DOI: 10.1158/1538-7445.Am2017-3566  0.365
2016 Chalmers ZR, Huang FW, Gay LM, Ali SM, Chmielecki J, Ross JS, Miller VA, Ganesan S, Stephens P, Garraway LA, Frampton GM. Analysis of tumor mutation burden (TMB) in >51,000 clinical cancer patients to identify novel non-coding PMS2 promoter mutations associated with increased TMB. Journal of Clinical Oncology. 34: 9572-9572. DOI: 10.1200/Jco.2016.34.15_Suppl.9572  0.341
2016 Chalmers ZR, Huang FW, Ali SM, Yelensky R, Chmielecki J, Ross JS, Miller VA, Stephens PJ, Garraway LA, Frampton GM. Abstract 3576: Broad analysis of recurrent somatic mutations in cancer reveals a common novel non-coding mutation in the promoter of PMS2 associated with greatly increased tumor mutation load Cancer Research. 76: 3576-3576. DOI: 10.1158/1538-7445.Am2016-3576  0.381
2015 Huang FW, Bielski CM, Rinne ML, Hahn WC, Sellers WR, Stegmeier F, Garraway LA, Kryukov GV. TERT promoter mutations and monoallelic activation of TERT in cancer. Oncogenesis. 4: e176. PMID 26657580 DOI: 10.1038/oncsis.2015.39  0.303
2013 Huang FW, Hodis E, Xu MJ, Kryukov GV, Chin L, Garraway LA. Highly recurrent TERT promoter mutations in human melanoma. Science (New York, N.Y.). 339: 957-9. PMID 23348506 DOI: 10.1126/Science.1229259  0.387
2013 Huang FW, Hodis E, Xu MJ, Kryukov G, Chin L, Garraway LA. Abstract LB-228: The identification of recurrent non-coding mutations in melanoma. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-228  0.373
2013 Allen EMV, Wagle N, Keizun A, Kryukov G, McKenna A, Huang F, Hiller E, Rainville I, Auclair D, Ambrogio L, Gray S, Joffe S, Getz G, Garber J, Garraway L. Abstract 2570: An integrated germline analysis platform for comprehensive clinical cancer genomics. Cancer Research. 73: 2570-2570. DOI: 10.1158/1538-7445.Am2013-2570  0.326
2011 Chen W, Huang FW, de Renshaw TB, Andrews NC. Skeletal muscle hemojuvelin is dispensable for systemic iron homeostasis. Blood. 117: 6319-25. PMID 21493799 DOI: 10.1182/Blood-2010-12-327957  0.61
2007 Babitt JL, Huang FW, Xia Y, Sidis Y, Andrews NC, Lin HY. Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance. The Journal of Clinical Investigation. 117: 1933-9. PMID 17607365 DOI: 10.1172/Jci31342  0.647
2006 Babitt JL, Huang FW, Wrighting DM, Xia Y, Sidis Y, Samad TA, Campagna JA, Chung RT, Schneyer AL, Woolf CJ, Andrews NC, Lin HY. Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression. Nature Genetics. 38: 531-9. PMID 16604073 DOI: 10.1038/Ng1777  0.723
2006 Schmidt PJ, Huang FW, Wrighting DM, Toran PT, Andrews NC. Hepcidin Expression Is Regulated by a Complex of Hemochromatosis-Associated Proteins. Blood. 108: 267-267. DOI: 10.1182/Blood.V108.11.267.267  0.728
2005 Huang FW, Pinkus JL, Pinkus GS, Fleming MD, Andrews NC. A mouse model of juvenile hemochromatosis. The Journal of Clinical Investigation. 115: 2187-91. PMID 16075059 DOI: 10.1172/Jci25049  0.644
2005 Huang FW, Babitt JL, Wrighting DM, Samad TA, Xia Y, Sidis Y, Campagna JA, Chung RT, Schneyer AL, Woolf CJ, Andrews NC, Lin HY. Hemojuvelin Acts as a Bone Morphogenetic Protein Co-Receptor To Regulate Hepcidin Expression. Blood. 106: 511-511. DOI: 10.1182/Blood.V106.11.511.511  0.722
2004 Huang FW, Rubio-Aliaga I, Kushner JP, Andrews NC, Fleming MD. Identification of a novel mutation (C321X) in HJV. Blood. 104: 2176-7. PMID 15138164 DOI: 10.1182/Blood-2004-01-0400  0.595
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