Lisa M. Shantz - Publications

Affiliations: 
Pennsylvania State University, State College, PA, United States 
Area:
Genetics, Physiology Biology, Oncology, Cell Biology

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Osei-Amponsa V, Buckwalter JM, Shuman L, Zheng Z, Yamashita H, Walter V, Wildermuth T, Ellis-Mohl J, Liu C, Warrick JI, Shantz LM, Feehan RP, Al-Ahmadie H, Mendelsohn C, Raman JD, et al. Hypermethylation of FOXA1 and allelic loss of PTEN drive squamous differentiation and promote heterogeneity in bladder cancer. Oncogene. PMID 31636388 DOI: 10.1038/S41388-019-1063-4  0.38
2019 Stump CL, Feehan RP, Jordan T, Shantz LM, Nowotarski SL. Knocking down raptor in human keratinocytes affects ornithine decarboxylase in a post-transcriptional Manner following ultraviolet B exposure. Amino Acids. PMID 30972602 DOI: 10.1007/S00726-019-02732-3  0.805
2018 Nowotarski SL, Feehan RP, Presloid C, Shantz LM. Knockout of Raptor destabilizes ornithine decarboxylase mRNA and decreases binding of HuR to the ODC transcript in cells exposed to ultraviolet-B irradiation. Biochemical and Biophysical Research Communications. PMID 30314695 DOI: 10.1016/J.Bbrc.2018.10.019  0.813
2018 Feehan RP, Nelson AM, Shantz LM. Inhibition of mTORC2 enhances UVB-induced apoptosis in keratinocytes through a mechanism dependent on the FOXO3a transcriptional target NOXA but independent of TRAIL. Cellular Signalling. 52: 35-47. PMID 30172026 DOI: 10.1016/J.Cellsig.2018.08.018  0.402
2017 Nowotarski SL, Shantz LM. The ODC 3'-Untranslated Region and 5'-Untranslated Region Contain cis-Regulatory Elements: Implications for Carcinogenesis. Medical Sciences (Basel, Switzerland). 6. PMID 29271923 DOI: 10.3390/Medsci6010002  0.761
2016 Feehan RP, Shantz LM. Molecular signaling cascades involved in nonmelanoma skin carcinogenesis. The Biochemical Journal. 473: 2973-94. PMID 27679857 DOI: 10.1042/Bcj20160471  0.377
2016 Nowotarski SL, Origanti S, Sass-Kuhn S, Shantz LM. Destabilization of the ornithine decarboxylase mRNA transcript by the RNA-binding protein tristetraprolin. Amino Acids. PMID 27193233 DOI: 10.1007/S00726-016-2261-9  0.78
2016 Feehan RP, Shantz LM. Negative regulation of the FOXO3a transcription factor by mTORC2 induces a pro-survival response following exposure to ultraviolet-B irradiation. Cellular Signalling. 28: 798-809. PMID 27058291 DOI: 10.1016/J.Cellsig.2016.03.013  0.428
2015 Nowotarski SL, Feith DJ, Shantz LM. Skin Carcinogenesis Studies Using Mouse Models with Altered Polyamines. Cancer Growth and Metastasis. 8: 17-27. PMID 26380554 DOI: 10.4137/CGM.S21219  0.732
2015 Carr TD, Feehan RP, Hall MN, Rüegg MA, Shantz LM. Conditional disruption of rictor demonstrates a direct requirement for mTORC2 in skin tumor development and continued growth of established tumors. Carcinogenesis. 36: 487-97. PMID 25740823 DOI: 10.1093/Carcin/Bgv012  0.391
2015 Feehan RP, Shantz LM. Abstract 27: The role of the mTORC2-dependent regulation of FOXO3a in UVB-induced apoptosis Cancer Research. 75: 27-27. DOI: 10.1158/1538-7445.Am2015-27  0.48
2012 Carr TD, DiGiovanni J, Lynch CJ, Shantz LM. Inhibition of mTOR suppresses UVB-induced keratinocyte proliferation and survival Cancer Prevention Research. 5: 1394-1404. PMID 23129577 DOI: 10.1158/1940-6207.Capr-12-0272-T  0.388
2012 Zhang Y, Cheng Y, Ren X, Hori T, Huber-Keener KJ, Zhang L, Yap KL, Liu D, Shantz L, Qin ZH, Zhang S, Wang J, Wang HG, Shih IeM, Yang JM. Dysfunction of nucleus accumbens-1 activates cellular senescence and inhibits tumor cell proliferation and oncogenesis. Cancer Research. 72: 4262-75. PMID 22665267 DOI: 10.1158/0008-5472.Can-12-0139  0.476
2012 Shi C, Cooper TK, McCloskey DE, Glick AB, Shantz LM, Feith DJ. S-adenosylmethionine decarboxylase overexpression inhibits mouse skin tumor promotion. Carcinogenesis. 33: 1310-8. PMID 22610166 DOI: 10.1093/Carcin/Bgs184  0.44
2012 Origanti S, Nowotarski SL, Carr TD, Sass-Kuhn S, Xiao L, Wang JY, Shantz LM. Ornithine decarboxylase mRNA is stabilized in an mTORC1-dependent manner in Ras-transformed cells. The Biochemical Journal. 442: 199-207. PMID 22070140 DOI: 10.1042/Bj20111464  0.771
2012 Carr TD, Feith DJ, Shantz LM. Abstract 5219: The role of MEK and Antizyme in keratinocyte stem cell expansion and differentiation Cancer Research. 72: 5219-5219. DOI: 10.1158/1538-7445.Am2012-5219  0.428
2011 Nowotarski SL, Origanti S, Shantz LM. Posttranscriptional regulation of ornithine decarboxylase. Methods in Molecular Biology (Clifton, N.J.). 720: 279-92. PMID 21318880 DOI: 10.1007/978-1-61779-034-8_17  0.779
2010 Nowotarski SL, Shantz LM. Cytoplasmic accumulation of the RNA-binding protein HuR stabilizes the ornithine decarboxylase transcript in a murine nonmelanoma skin cancer model. The Journal of Biological Chemistry. 285: 31885-94. PMID 20685649 DOI: 10.1074/Jbc.M110.148767  0.804
2010 Govoni M, Bonavita F, Shantz LM, Guarnieri C, Giordano E. Overexpression of ornithine decarboxylase increases myogenic potential of H9c2 rat myoblasts. Amino Acids. 38: 541-7. PMID 20013009 DOI: 10.1007/S00726-009-0415-8  0.386
2010 Nowotarski SL, Shantz LM. Abstract 3161: The RNA binding protein HuR stabilizes the ornithine decarboxylase (ODC) transcript in non-melanoma skin cancer Cancer Research. 70: 3161-3161. DOI: 10.1158/1538-7445.Am10-3161  0.804
2007 Deignan JL, Livesay JC, Shantz LM, Pegg AE, O'Brien WE, Iyer RK, Cederbaum SD, Grody WW. Polyamine homeostasis in arginase knockout mice. American Journal of Physiology. Cell Physiology. 293: C1296-301. PMID 17686999 DOI: 10.1152/Ajpcell.00393.2006  0.347
2007 Levin VA, Jochec JL, Shantz LM, Aldape KD. Relationship between ornithine decarboxylase levels in anaplastic gliomas and progression-free survival in patients treated with DFMO-PCV chemotherapy. International Journal of Cancer. Journal International Du Cancer. 121: 2279-83. PMID 17582600 DOI: 10.1002/Ijc.22914  0.34
2007 Origanti S, Shantz LM. Ras transformation of RIE-1 cells activates cap-independent translation of ornithine decarboxylase: regulation by the Raf/MEK/ERK and phosphatidylinositol 3-kinase pathways. Cancer Research. 67: 4834-42. PMID 17510413 DOI: 10.1158/0008-5472.Can-06-4627  0.767
2007 Shantz LM, Levin VA. Regulation of ornithine decarboxylase during oncogenic transformation: mechanisms and therapeutic potential. Amino Acids. 33: 213-23. PMID 17443268 DOI: 10.1007/S00726-007-0531-2  0.544
2007 Feith DJ, Shantz LM, Shoop PL, Keefer KA, Prakashagowda C, Pegg AE. Mouse skin chemical carcinogenesis is inhibited by antizyme in promotion-sensitive and promotion-resistant genetic backgrounds. Molecular Carcinogenesis. 46: 453-65. PMID 17219416 DOI: 10.1002/Mc.20294  0.382
2006 Kim SW, Mangold U, Waghorne C, Mobascher A, Shantz L, Banyard J, Zetter BR. Regulation of cell proliferation by the antizyme inhibitor: evidence for an antizyme-independent mechanism. Journal of Cell Science. 119: 2583-91. PMID 16735445 DOI: 10.1242/Jcs.02966  0.441
2006 Tantini B, Fiumana E, Cetrullo S, Pignatti C, Bonavita F, Shantz LM, Giordano E, Muscari C, Flamigni F, Guarnieri C, Stefanelli C, Caldarera CM. Involvement of polyamines in apoptosis of cardiac myoblasts in a model of simulated ischemia Journal of Molecular and Cellular Cardiology. 40: 775-782. PMID 16678846 DOI: 10.1016/J.Yjmcc.2006.03.002  0.341
2006 Feith DJ, Origanti S, Shoop PL, Sass-Kuhn S, Shantz LM. Tumor suppressor activity of ODC antizyme in MEK-driven skin tumorigenesis. Carcinogenesis. 27: 1090-8. PMID 16400186 DOI: 10.1093/Carcin/Bgi343  0.733
2006 Nisenberg O, Pegg AE, Welsh PA, Keefer K, Shantz LM. Overproduction of cardiac S-adenosylmethionine decarboxylase in transgenic mice. The Biochemical Journal. 393: 295-302. PMID 16153183 DOI: 10.1042/Bj20051196  0.361
2005 Feith DJ, Bol DK, Carboni JM, Lynch MJ, Sass-Kuhn S, Shoop PL, Shantz LM. Induction of ornithine decarboxylase activity is a necessary step for mitogen-activated protein kinase kinase-induced skin tumorigenesis. Cancer Research. 65: 572-8. PMID 15695401  0.301
2004 Ikeguchi Y, Wang X, McCloskey DE, Coleman CS, Nelson P, Hu G, Shantz LM, Pegg AE. Characterization of transgenic mice with widespread overexpression of spermine synthase. The Biochemical Journal. 381: 701-7. PMID 15104536 DOI: 10.1042/Bj20040419  0.34
2004 Shantz LM. Transcriptional and translational control of ornithine decarboxylase during Ras transformation. The Biochemical Journal. 377: 257-64. PMID 14519103 DOI: 10.1042/Bj20030778  0.475
2003 Pegg AE, Feith DJ, Fong LY, Coleman CS, O'Brien TG, Shantz LM. Transgenic mouse models for studies of the role of polyamines in normal, hypertrophic and neoplastic growth. Biochemical Society Transactions. 31: 356-60. PMID 12653638 DOI: 10.1042/Bst0310356  0.417
2002 Shantz LM, Guo Y, Sawicki JA, Pegg AE, O'Brien TG. Overexpression of a dominant-negative ornithine decarboxylase in mouse skin: effect on enzyme activity and papilloma formation. Carcinogenesis. 23: 657-64. PMID 11960919 DOI: 10.1093/Carcin/23.4.657  0.379
2001 Shantz LM, Feith DJ, Pegg AE. Targeted overexpression of ornithine decarboxylase enhances beta-adrenergic agonist-induced cardiac hypertrophy. The Biochemical Journal. 358: 25-32. PMID 11485548 DOI: 10.1042/0264-6021:3580025  0.316
2000 Mackintosh CA, Feith DJ, Shantz LM, Pegg AE. Overexpression of antizyme in the hearts of transgenic mice prevents the isoprenaline-induced increase in cardiac ornithine decarboxylase activity and polyamines, but does not prevent cardiac hypertrophy. The Biochemical Journal. 350: 645-53. PMID 10970775 DOI: 10.1042/Bj3500645  0.35
1999 Shantz LM, Pegg AE. Translational regulation of ornithine decarboxylase and other enzymes of the polyamine pathway International Journal of Biochemistry and Cell Biology. 31: 107-122. PMID 10216947 DOI: 10.1016/S1357-2725(98)00135-6  0.542
1999 Kimball SR, Shantz LM, Horetsky RL, Jefferson LS. Leucine regulates translation of specific mRNAs in L6 myoblasts through mTOR-mediated changes in availability of eIF4E and phosphorylation of ribosomal protein S6. The Journal of Biological Chemistry. 274: 11647-52. PMID 10206976 DOI: 10.1074/Jbc.274.17.11647  0.473
1996 Ruan H, Shantz LM, Pegg AE, Morris DR. The upstream open reading frame of the mRNA encoding S-adenosylmethionine decarboxylase is a polyamine-responsive translational control element. The Journal of Biological Chemistry. 271: 29576-82. PMID 8939886 DOI: 10.1074/Jbc.271.47.29576  0.413
1996 Pegg AE, Shantz LM, Coleman CS. Ornithine decarboxylase as a target for chemoprevention. Journal of Cellular Biochemistry. Supplement. 22: 132-8. PMID 8538190 DOI: 10.1002/Jcb.240590817  0.509
1995 Pegg AE, Shantz LM, Coleman CS. Ornithine decarboxylase: structure, function and translational regulation. Biochemical Society Transactions. 22: 846-52. PMID 7698473 DOI: 10.1042/Bst0220846  0.332
1994 Shantz LM, Viswanath R, Pegg AE. Role of the 5'-untranslated region of mRNA in the synthesis of S-adenosylmethionine decarboxylase and its regulation by spermine. The Biochemical Journal. 765-72. PMID 7945201 DOI: 10.1042/Bj3020765  0.495
1993 Shantz LM, Holm I, Jänne OA, Pegg AE. Regulation of S-adenosylmethionine decarboxylase activity by alterations in the intracellular polyamine content. The Biochemical Journal. 511-8. PMID 1463454 DOI: 10.1042/Bj2880511  0.469
1989 Shantz LM, Talalay P, Gordon GB. Mechanism of inhibition of growth of 3T3-L1 fibroblasts and their differentiation to adipocytes by dehydroepiandrosterone and related steroids: Role of glucose-6-phosphate dehydrogenase Proceedings of the National Academy of Sciences of the United States of America. 86: 3852-3856. PMID 2524835 DOI: 10.1073/Pnas.86.10.3852  0.335
1988 Hamburger AW, Parnes H, Gordon GB, Shantz LM, O'Donnell KA, Aisner J. Megestrol acetate-induced differentiation of 3T3-L1 adipocytes in vitro. Seminars in Oncology. 15: 76-78. DOI: 10.5555/Uri:Pii:0093775488901157  0.332
1987 Gordon GB, Shantz LM, Talalay P. Modulation of growth, differentiation and carcinogenesis by dehydroepiandrosterone Advances in Enzyme Regulation. 26: 355-382. PMID 2960133 DOI: 10.1016/0065-2571(87)90023-9  0.339
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