Year |
Citation |
Score |
2019 |
Osei-Amponsa V, Buckwalter JM, Shuman L, Zheng Z, Yamashita H, Walter V, Wildermuth T, Ellis-Mohl J, Liu C, Warrick JI, Shantz LM, Feehan RP, Al-Ahmadie H, Mendelsohn C, Raman JD, et al. Hypermethylation of FOXA1 and allelic loss of PTEN drive squamous differentiation and promote heterogeneity in bladder cancer. Oncogene. PMID 31636388 DOI: 10.1038/S41388-019-1063-4 |
0.38 |
|
2019 |
Stump CL, Feehan RP, Jordan T, Shantz LM, Nowotarski SL. Knocking down raptor in human keratinocytes affects ornithine decarboxylase in a post-transcriptional Manner following ultraviolet B exposure. Amino Acids. PMID 30972602 DOI: 10.1007/S00726-019-02732-3 |
0.805 |
|
2018 |
Nowotarski SL, Feehan RP, Presloid C, Shantz LM. Knockout of Raptor destabilizes ornithine decarboxylase mRNA and decreases binding of HuR to the ODC transcript in cells exposed to ultraviolet-B irradiation. Biochemical and Biophysical Research Communications. PMID 30314695 DOI: 10.1016/J.Bbrc.2018.10.019 |
0.813 |
|
2018 |
Feehan RP, Nelson AM, Shantz LM. Inhibition of mTORC2 enhances UVB-induced apoptosis in keratinocytes through a mechanism dependent on the FOXO3a transcriptional target NOXA but independent of TRAIL. Cellular Signalling. 52: 35-47. PMID 30172026 DOI: 10.1016/J.Cellsig.2018.08.018 |
0.402 |
|
2017 |
Nowotarski SL, Shantz LM. The ODC 3'-Untranslated Region and 5'-Untranslated Region Contain cis-Regulatory Elements: Implications for Carcinogenesis. Medical Sciences (Basel, Switzerland). 6. PMID 29271923 DOI: 10.3390/Medsci6010002 |
0.761 |
|
2016 |
Feehan RP, Shantz LM. Molecular signaling cascades involved in nonmelanoma skin carcinogenesis. The Biochemical Journal. 473: 2973-94. PMID 27679857 DOI: 10.1042/Bcj20160471 |
0.377 |
|
2016 |
Nowotarski SL, Origanti S, Sass-Kuhn S, Shantz LM. Destabilization of the ornithine decarboxylase mRNA transcript by the RNA-binding protein tristetraprolin. Amino Acids. PMID 27193233 DOI: 10.1007/S00726-016-2261-9 |
0.78 |
|
2016 |
Feehan RP, Shantz LM. Negative regulation of the FOXO3a transcription factor by mTORC2 induces a pro-survival response following exposure to ultraviolet-B irradiation. Cellular Signalling. 28: 798-809. PMID 27058291 DOI: 10.1016/J.Cellsig.2016.03.013 |
0.428 |
|
2015 |
Nowotarski SL, Feith DJ, Shantz LM. Skin Carcinogenesis Studies Using Mouse Models with Altered Polyamines. Cancer Growth and Metastasis. 8: 17-27. PMID 26380554 DOI: 10.4137/CGM.S21219 |
0.732 |
|
2015 |
Carr TD, Feehan RP, Hall MN, Rüegg MA, Shantz LM. Conditional disruption of rictor demonstrates a direct requirement for mTORC2 in skin tumor development and continued growth of established tumors. Carcinogenesis. 36: 487-97. PMID 25740823 DOI: 10.1093/Carcin/Bgv012 |
0.391 |
|
2015 |
Feehan RP, Shantz LM. Abstract 27: The role of the mTORC2-dependent regulation of FOXO3a in UVB-induced apoptosis Cancer Research. 75: 27-27. DOI: 10.1158/1538-7445.Am2015-27 |
0.48 |
|
2012 |
Carr TD, DiGiovanni J, Lynch CJ, Shantz LM. Inhibition of mTOR suppresses UVB-induced keratinocyte proliferation and survival Cancer Prevention Research. 5: 1394-1404. PMID 23129577 DOI: 10.1158/1940-6207.Capr-12-0272-T |
0.388 |
|
2012 |
Zhang Y, Cheng Y, Ren X, Hori T, Huber-Keener KJ, Zhang L, Yap KL, Liu D, Shantz L, Qin ZH, Zhang S, Wang J, Wang HG, Shih IeM, Yang JM. Dysfunction of nucleus accumbens-1 activates cellular senescence and inhibits tumor cell proliferation and oncogenesis. Cancer Research. 72: 4262-75. PMID 22665267 DOI: 10.1158/0008-5472.Can-12-0139 |
0.476 |
|
2012 |
Shi C, Cooper TK, McCloskey DE, Glick AB, Shantz LM, Feith DJ. S-adenosylmethionine decarboxylase overexpression inhibits mouse skin tumor promotion. Carcinogenesis. 33: 1310-8. PMID 22610166 DOI: 10.1093/Carcin/Bgs184 |
0.44 |
|
2012 |
Origanti S, Nowotarski SL, Carr TD, Sass-Kuhn S, Xiao L, Wang JY, Shantz LM. Ornithine decarboxylase mRNA is stabilized in an mTORC1-dependent manner in Ras-transformed cells. The Biochemical Journal. 442: 199-207. PMID 22070140 DOI: 10.1042/Bj20111464 |
0.771 |
|
2012 |
Carr TD, Feith DJ, Shantz LM. Abstract 5219: The role of MEK and Antizyme in keratinocyte stem cell expansion and differentiation Cancer Research. 72: 5219-5219. DOI: 10.1158/1538-7445.Am2012-5219 |
0.428 |
|
2011 |
Nowotarski SL, Origanti S, Shantz LM. Posttranscriptional regulation of ornithine decarboxylase. Methods in Molecular Biology (Clifton, N.J.). 720: 279-92. PMID 21318880 DOI: 10.1007/978-1-61779-034-8_17 |
0.779 |
|
2010 |
Nowotarski SL, Shantz LM. Cytoplasmic accumulation of the RNA-binding protein HuR stabilizes the ornithine decarboxylase transcript in a murine nonmelanoma skin cancer model. The Journal of Biological Chemistry. 285: 31885-94. PMID 20685649 DOI: 10.1074/Jbc.M110.148767 |
0.804 |
|
2010 |
Govoni M, Bonavita F, Shantz LM, Guarnieri C, Giordano E. Overexpression of ornithine decarboxylase increases myogenic potential of H9c2 rat myoblasts. Amino Acids. 38: 541-7. PMID 20013009 DOI: 10.1007/S00726-009-0415-8 |
0.386 |
|
2010 |
Nowotarski SL, Shantz LM. Abstract 3161: The RNA binding protein HuR stabilizes the ornithine decarboxylase (ODC) transcript in non-melanoma skin cancer Cancer Research. 70: 3161-3161. DOI: 10.1158/1538-7445.Am10-3161 |
0.804 |
|
2007 |
Deignan JL, Livesay JC, Shantz LM, Pegg AE, O'Brien WE, Iyer RK, Cederbaum SD, Grody WW. Polyamine homeostasis in arginase knockout mice. American Journal of Physiology. Cell Physiology. 293: C1296-301. PMID 17686999 DOI: 10.1152/Ajpcell.00393.2006 |
0.347 |
|
2007 |
Levin VA, Jochec JL, Shantz LM, Aldape KD. Relationship between ornithine decarboxylase levels in anaplastic gliomas and progression-free survival in patients treated with DFMO-PCV chemotherapy. International Journal of Cancer. Journal International Du Cancer. 121: 2279-83. PMID 17582600 DOI: 10.1002/Ijc.22914 |
0.34 |
|
2007 |
Origanti S, Shantz LM. Ras transformation of RIE-1 cells activates cap-independent translation of ornithine decarboxylase: regulation by the Raf/MEK/ERK and phosphatidylinositol 3-kinase pathways. Cancer Research. 67: 4834-42. PMID 17510413 DOI: 10.1158/0008-5472.Can-06-4627 |
0.767 |
|
2007 |
Shantz LM, Levin VA. Regulation of ornithine decarboxylase during oncogenic transformation: mechanisms and therapeutic potential. Amino Acids. 33: 213-23. PMID 17443268 DOI: 10.1007/S00726-007-0531-2 |
0.544 |
|
2007 |
Feith DJ, Shantz LM, Shoop PL, Keefer KA, Prakashagowda C, Pegg AE. Mouse skin chemical carcinogenesis is inhibited by antizyme in promotion-sensitive and promotion-resistant genetic backgrounds. Molecular Carcinogenesis. 46: 453-65. PMID 17219416 DOI: 10.1002/Mc.20294 |
0.382 |
|
2006 |
Kim SW, Mangold U, Waghorne C, Mobascher A, Shantz L, Banyard J, Zetter BR. Regulation of cell proliferation by the antizyme inhibitor: evidence for an antizyme-independent mechanism. Journal of Cell Science. 119: 2583-91. PMID 16735445 DOI: 10.1242/Jcs.02966 |
0.441 |
|
2006 |
Tantini B, Fiumana E, Cetrullo S, Pignatti C, Bonavita F, Shantz LM, Giordano E, Muscari C, Flamigni F, Guarnieri C, Stefanelli C, Caldarera CM. Involvement of polyamines in apoptosis of cardiac myoblasts in a model of simulated ischemia Journal of Molecular and Cellular Cardiology. 40: 775-782. PMID 16678846 DOI: 10.1016/J.Yjmcc.2006.03.002 |
0.341 |
|
2006 |
Feith DJ, Origanti S, Shoop PL, Sass-Kuhn S, Shantz LM. Tumor suppressor activity of ODC antizyme in MEK-driven skin tumorigenesis. Carcinogenesis. 27: 1090-8. PMID 16400186 DOI: 10.1093/Carcin/Bgi343 |
0.733 |
|
2006 |
Nisenberg O, Pegg AE, Welsh PA, Keefer K, Shantz LM. Overproduction of cardiac S-adenosylmethionine decarboxylase in transgenic mice. The Biochemical Journal. 393: 295-302. PMID 16153183 DOI: 10.1042/Bj20051196 |
0.361 |
|
2005 |
Feith DJ, Bol DK, Carboni JM, Lynch MJ, Sass-Kuhn S, Shoop PL, Shantz LM. Induction of ornithine decarboxylase activity is a necessary step for mitogen-activated protein kinase kinase-induced skin tumorigenesis. Cancer Research. 65: 572-8. PMID 15695401 |
0.301 |
|
2004 |
Ikeguchi Y, Wang X, McCloskey DE, Coleman CS, Nelson P, Hu G, Shantz LM, Pegg AE. Characterization of transgenic mice with widespread overexpression of spermine synthase. The Biochemical Journal. 381: 701-7. PMID 15104536 DOI: 10.1042/Bj20040419 |
0.34 |
|
2004 |
Shantz LM. Transcriptional and translational control of ornithine decarboxylase during Ras transformation. The Biochemical Journal. 377: 257-64. PMID 14519103 DOI: 10.1042/Bj20030778 |
0.475 |
|
2003 |
Pegg AE, Feith DJ, Fong LY, Coleman CS, O'Brien TG, Shantz LM. Transgenic mouse models for studies of the role of polyamines in normal, hypertrophic and neoplastic growth. Biochemical Society Transactions. 31: 356-60. PMID 12653638 DOI: 10.1042/Bst0310356 |
0.417 |
|
2002 |
Shantz LM, Guo Y, Sawicki JA, Pegg AE, O'Brien TG. Overexpression of a dominant-negative ornithine decarboxylase in mouse skin: effect on enzyme activity and papilloma formation. Carcinogenesis. 23: 657-64. PMID 11960919 DOI: 10.1093/Carcin/23.4.657 |
0.379 |
|
2001 |
Shantz LM, Feith DJ, Pegg AE. Targeted overexpression of ornithine decarboxylase enhances beta-adrenergic agonist-induced cardiac hypertrophy. The Biochemical Journal. 358: 25-32. PMID 11485548 DOI: 10.1042/0264-6021:3580025 |
0.316 |
|
2000 |
Mackintosh CA, Feith DJ, Shantz LM, Pegg AE. Overexpression of antizyme in the hearts of transgenic mice prevents the isoprenaline-induced increase in cardiac ornithine decarboxylase activity and polyamines, but does not prevent cardiac hypertrophy. The Biochemical Journal. 350: 645-53. PMID 10970775 DOI: 10.1042/Bj3500645 |
0.35 |
|
1999 |
Shantz LM, Pegg AE. Translational regulation of ornithine decarboxylase and other enzymes of the polyamine pathway International Journal of Biochemistry and Cell Biology. 31: 107-122. PMID 10216947 DOI: 10.1016/S1357-2725(98)00135-6 |
0.542 |
|
1999 |
Kimball SR, Shantz LM, Horetsky RL, Jefferson LS. Leucine regulates translation of specific mRNAs in L6 myoblasts through mTOR-mediated changes in availability of eIF4E and phosphorylation of ribosomal protein S6. The Journal of Biological Chemistry. 274: 11647-52. PMID 10206976 DOI: 10.1074/Jbc.274.17.11647 |
0.473 |
|
1996 |
Ruan H, Shantz LM, Pegg AE, Morris DR. The upstream open reading frame of the mRNA encoding S-adenosylmethionine decarboxylase is a polyamine-responsive translational control element. The Journal of Biological Chemistry. 271: 29576-82. PMID 8939886 DOI: 10.1074/Jbc.271.47.29576 |
0.413 |
|
1996 |
Pegg AE, Shantz LM, Coleman CS. Ornithine decarboxylase as a target for chemoprevention. Journal of Cellular Biochemistry. Supplement. 22: 132-8. PMID 8538190 DOI: 10.1002/Jcb.240590817 |
0.509 |
|
1995 |
Pegg AE, Shantz LM, Coleman CS. Ornithine decarboxylase: structure, function and translational regulation. Biochemical Society Transactions. 22: 846-52. PMID 7698473 DOI: 10.1042/Bst0220846 |
0.332 |
|
1994 |
Shantz LM, Viswanath R, Pegg AE. Role of the 5'-untranslated region of mRNA in the synthesis of S-adenosylmethionine decarboxylase and its regulation by spermine. The Biochemical Journal. 765-72. PMID 7945201 DOI: 10.1042/Bj3020765 |
0.495 |
|
1993 |
Shantz LM, Holm I, Jänne OA, Pegg AE. Regulation of S-adenosylmethionine decarboxylase activity by alterations in the intracellular polyamine content. The Biochemical Journal. 511-8. PMID 1463454 DOI: 10.1042/Bj2880511 |
0.469 |
|
1989 |
Shantz LM, Talalay P, Gordon GB. Mechanism of inhibition of growth of 3T3-L1 fibroblasts and their differentiation to adipocytes by dehydroepiandrosterone and related steroids: Role of glucose-6-phosphate dehydrogenase Proceedings of the National Academy of Sciences of the United States of America. 86: 3852-3856. PMID 2524835 DOI: 10.1073/Pnas.86.10.3852 |
0.335 |
|
1988 |
Hamburger AW, Parnes H, Gordon GB, Shantz LM, O'Donnell KA, Aisner J. Megestrol acetate-induced differentiation of 3T3-L1 adipocytes in vitro. Seminars in Oncology. 15: 76-78. DOI: 10.5555/Uri:Pii:0093775488901157 |
0.332 |
|
1987 |
Gordon GB, Shantz LM, Talalay P. Modulation of growth, differentiation and carcinogenesis by dehydroepiandrosterone Advances in Enzyme Regulation. 26: 355-382. PMID 2960133 DOI: 10.1016/0065-2571(87)90023-9 |
0.339 |
|
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