| Year |
Citation |
Score |
| 2023 |
Niknejad N, Fox D, Burwinkel JL, Zarrin-Khameh N, Cho S, Soriano A, Cast AE, Lopez MF, Huppert KA, Rigo F, Huppert SS, Jafar-Nejad P, Jafar-Nejad H. Antisense oligonucleotide silencing of a glycosyltransferase, Poglut1, improves the liver phenotypes in mouse models of Alagille syndrome. Hepatology (Baltimore, Md.). PMID 37021797 DOI: 10.1097/HEP.0000000000000380 |
0.439 |
|
| 2022 |
Huppert SS, Schwartz RE. Multiple Facets of Cellular Homeostasis and Regeneration of the Mammalian Liver. Annual Review of Physiology. PMID 36270290 DOI: 10.1146/annurev-physiol-032822-094134 |
0.465 |
|
| 2019 |
Adams JM, Huppert KA, Castro EC, Lopez MF, Niknejad N, Subramanian S, Zarrin-Khameh N, Finegold MJ, Huppert SS, Jafar-Nejad H. Sox9 is a modifier of the liver disease severity in a mouse model of Alagille syndrome. Hepatology (Baltimore, Md.). PMID 31469182 DOI: 10.1002/Hep.30912 |
0.597 |
|
| 2019 |
Huppert SS, Iwafuchi-Doi M. Molecular regulation of mammalian hepatic architecture. Current Topics in Developmental Biology. 132: 91-136. PMID 30797519 DOI: 10.1016/Bs.Ctdb.2018.12.003 |
0.587 |
|
| 2018 |
Schaub JR, Huppert KA, Kurial SNT, Hsu BY, Cast AE, Donnelly B, Karns RA, Chen F, Rezvani M, Luu HY, Mattis AN, Rougemont AL, Rosenthal P, Huppert SS, Willenbring H. De novo formation of the biliary system by TGFβ-mediated hepatocyte transdifferentiation. Nature. PMID 29720662 DOI: 10.1038/S41586-018-0075-5 |
0.628 |
|
| 2018 |
Ng VH, Hang BI, Sawyer LM, Neitzel LR, Crispi EE, Rose KL, Popay TM, Zhong A, Lee LA, Tansey WP, Huppert S, Lee E. Phosphorylation of XIAP at threonine 180 controls its activity in Wnt signaling. Journal of Cell Science. PMID 29678905 DOI: 10.1242/Jcs.210575 |
0.353 |
|
| 2018 |
Soini T, Pihlajoki M, Andersson N, Lohi J, Huppert KA, Rudnick DA, Huppert SS, Wilson DB, Pakarinen MP, Heikinheimo M. Transcription Factor GATA6: A Novel Marker and Putative Inducer of Ductal Metaplasia in Biliary Atresia. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 29388792 DOI: 10.1152/ajpgi.00362.2017 |
0.465 |
|
| 2016 |
Huppert SS, Campbell KM. Emerging advancements in liver regeneration and organogenesis as tools for liver replacement. Current Opinion in Organ Transplantation. PMID 27755169 DOI: 10.1097/Mot.0000000000000365 |
0.523 |
|
| 2016 |
Broadus MR, Chen TW, Neitzel LR, Ng VH, Jodoin JN, Lee LA, Salic A, Robbins DJ, Capobianco AJ, Patton JG, Huppert SS, Lee E. Identification of a Paralog-Specific Notch1 Intracellular Domain Degron. Cell Reports. PMID 27210761 DOI: 10.1016/J.Celrep.2016.04.070 |
0.327 |
|
| 2015 |
Chen J, Ryzhova LM, Sewell-Loftin MK, Brown CB, Huppert SS, Baldwin HS, Merryman WD. Notch1 Mutation Leads to Valvular Calcification Through Enhanced Myofibroblast Mechanotransduction. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 1597-605. PMID 26023079 DOI: 10.1161/Atvbaha.114.305095 |
0.318 |
|
| 2015 |
Cast AE, Walter TJ, Huppert SS. Vascular patterning sets the stage for macro and micro hepatic architecture. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 244: 497-506. PMID 25370311 DOI: 10.1002/dvdy.24222 |
0.768 |
|
| 2014 |
Poling HM, Mohanty SK, Tiao GM, Huppert SS. A comprehensive analysis of aquaporin and secretory related gene expression in neonate and adult cholangiocytes. Gene Expression Patterns : Gep. 15: 96-103. PMID 24929031 DOI: 10.1016/J.Gep.2014.05.003 |
0.355 |
|
| 2014 |
Walter TJ, Cast AE, Huppert KA, Huppert SS. Epithelial VEGF signaling is required in the mouse liver for proper sinusoid endothelial cell identity and hepatocyte zonation in vivo. American Journal of Physiology. Gastrointestinal and Liver Physiology. 306: G849-62. PMID 24650547 DOI: 10.1152/Ajpgi.00426.2013 |
0.749 |
|
| 2014 |
Walter TJ, Vanderpool C, Cast AE, Huppert SS. Intrahepatic bile duct regeneration in mice does not require Hnf6 or Notch signaling through Rbpj. The American Journal of Pathology. 184: 1479-88. PMID 24631193 DOI: 10.1016/J.Ajpath.2014.01.030 |
0.756 |
|
| 2013 |
Miethke AG, Huppert SS. Fishing for biliary atresia susceptibility genes. Gastroenterology. 144: 878-81. PMID 23523832 DOI: 10.1053/J.Gastro.2013.03.017 |
0.447 |
|
| 2012 |
Murphy AJ, de Caestecker C, Pierce J, Boyle SC, Ayers GD, Zhao Z, Libes JM, Correa H, Walter T, Huppert SS, Perantoni AO, de Caestecker MP, Lovvorn HN. CITED1 expression in liver development and hepatoblastoma. Neoplasia (New York, N.Y.). 14: 1153-63. PMID 23308048 DOI: 10.1593/Neo.12958 |
0.747 |
|
| 2012 |
Walter TJ, Sparks EE, Huppert SS. 3-dimensional resin casting and imaging of mouse portal vein or intrahepatic bile duct system. Journal of Visualized Experiments : Jove. e4272. PMID 23128398 DOI: 10.3791/4272 |
0.713 |
|
| 2012 |
Humphreys R, Zheng W, Prince LS, Qu X, Brown C, Loomes K, Huppert SS, Baldwin S, Goudy S. Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients. Human Molecular Genetics. 21: 1374-83. PMID 22156581 DOI: 10.1093/Hmg/Ddr575 |
0.39 |
|
| 2012 |
Vanderpool C, Sparks EE, Huppert KA, Gannon M, Means AL, Huppert SS. Genetic interactions between hepatocyte nuclear factor-6 and notch signaling regulate mouse intrahepatic bile duct development in vivo Hepatology. 55: 233-243. PMID 21898486 DOI: 10.1002/Hep.24631 |
0.499 |
|
| 2011 |
Thorne CA, Lafleur B, Lewis M, Hanson AJ, Jernigan KK, Weaver DC, Huppert KA, Chen TW, Wichaidit C, Cselenyi CS, Tahinci E, Meyers KC, Waskow E, Orton D, Salic A, ... ... Huppert SS, et al. A biochemical screen for identification of small-molecule regulators of the Wnt pathway using Xenopus egg extracts. Journal of Biomolecular Screening. 16: 995-1006. PMID 21859680 DOI: 10.1177/1087057111416657 |
0.307 |
|
| 2011 |
Sparks EE, Perrien DS, Huppert KA, Peterson TE, Huppert SS. Defects in hepatic Notch signaling result in disruption of the communicating intrahepatic bile duct network in mice. Disease Models & Mechanisms. 4: 359-67. PMID 21282722 DOI: 10.1242/Dmm.005793 |
0.49 |
|
| 2011 |
Walter TJ, Huppert K, Huppert S. Investigating the mechanism of liver vascular development and the role of Notch signaling in liver morphogenesis Developmental Biology. 356: 166-167. DOI: 10.1016/J.Ydbio.2011.05.617 |
0.765 |
|
| 2010 |
Sparks EE, Huppert KA, Brown MA, Washington MK, Huppert SS. Notch signaling regulates formation of the three-dimensional architecture of intrahepatic bile ducts in mice. Hepatology (Baltimore, Md.). 51: 1391-400. PMID 20069650 DOI: 10.1002/Hep.23431 |
0.439 |
|
| 2009 |
Huppert SS, Magnuson MA. New complexity in differentiating stem cells toward hepatic and pancreatic fates. Science Signaling. 2: pe50. PMID 19671927 DOI: 10.1126/Scisignal.283Pe50 |
0.464 |
|
| 2008 |
Knutson SK, Chyla BJ, Amann JM, Bhaskara S, Huppert SS, Hiebert SW. Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks. The Embo Journal. 27: 1017-28. PMID 18354499 DOI: 10.1038/Emboj.2008.51 |
0.47 |
|
| 2007 |
Vooijs M, Ong CT, Hadland B, Huppert S, Liu Z, Korving J, van den Born M, Stappenbeck T, Wu Y, Clevers H, Kopan R. Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE. Development (Cambridge, England). 134: 535-44. PMID 17215306 DOI: 10.1242/Dev.02733 |
0.415 |
|
| 2006 |
Huppert SS. Progressive structural changes in the liver resulting from conditional loss of Notch signaling Developmental Biology. 295: 454. DOI: 10.1016/J.Ydbio.2006.04.399 |
0.518 |
|
| 2005 |
Huppert SS, Ilagan MX, De Strooper B, Kopan R. Analysis of Notch function in presomitic mesoderm suggests a gamma-secretase-independent role for presenilins in somite differentiation. Developmental Cell. 8: 677-88. PMID 15866159 DOI: 10.1016/J.Devcel.2005.02.019 |
0.356 |
|
| 2004 |
Nichols AM, Pan Y, Herreman A, Hadland BK, De Strooper B, Kopan R, Huppert SS. Notch pathway is dispensable for adipocyte specification. Genesis (New York, N.Y. : 2000). 40: 40-4. PMID 15354292 DOI: 10.1002/Gene.20061 |
0.343 |
|
| 2004 |
Hadland BK, Huppert SS, Kanungo J, Xue Y, Jiang R, Gridley T, Conlon RA, Cheng AM, Kopan R, Longmore GD. A requirement for Notch1 distinguishes 2 phases of definitive hematopoiesis during development. Blood. 104: 3097-105. PMID 15251982 DOI: 10.1182/Blood-2004-03-1224 |
0.444 |
|
| 2000 |
Huppert SS, Le A, Schroeter EH, Mumm JS, Saxena MT, Milner LA, Kopan R. Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1. Nature. 405: 966-70. PMID 10879540 DOI: 10.1038/35016111 |
0.382 |
|
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