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Johannes Broichhagen - Publications

Affiliations: 
École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland 
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38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ast J, Nasteska D, Fine NHF, Nieves DJ, Koszegi Z, Lanoiselée Y, Cuozzo F, Viloria K, Bacon A, Luu NT, Newsome PN, Calebiro D, Owen DM, Broichhagen J, Hodson DJ. Revealing the tissue-level complexity of endogenous glucagon-like peptide-1 receptor expression and signaling. Nature Communications. 14: 301. PMID 36653347 DOI: 10.1038/s41467-022-35716-1  0.335
2021 Kemter E, Müller A, Neukam M, Ivanova A, Klymiuk N, Renner S, Yang K, Broichhagen J, Kurome M, Zakhartchenko V, Kessler B, Knoch KP, Bickle M, Ludwig B, Johnsson K, et al. Sequential in vivo labeling of insulin secretory granule pools in - transgenic pigs. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34508004 DOI: 10.1073/pnas.2107665118  0.484
2021 Olaniru OE, Cheng J, Ast J, Arvaniti A, Atanes P, Gc H, King AJF, Jones PM, Broichhagen J, Hodson DJ, Persaud SJ. SNAP-tag-enabled super-resolution imaging reveals constitutive and agonist-dependent trafficking of GPR56 in pancreatic β-cells. Molecular Metabolism. 101285. PMID 34224919 DOI: 10.1016/j.molmet.2021.101285  0.3
2021 Gutzeit VA, Acosta-Ruiz A, Munguba H, Häfner S, Landra-Willm A, Mathes B, Mony J, Yarotski D, Börjesson K, Liston C, Sandoz G, Levitz J, Broichhagen J. A fine-tuned azobenzene for enhanced photopharmacology in vivo. Cell Chemical Biology. PMID 33735619 DOI: 10.1016/j.chembiol.2021.02.020  0.306
2020 Poc P, Gutzeit VA, Ast J, Lee J, Jones BJ, D'Este E, Mathes B, Lehmann M, Hodson DJ, Levitz J, Broichhagen J. Interrogating surface intracellular transmembrane receptor populations using cell-impermeable SNAP-tag substrates. Chemical Science. 11: 7871-7883. PMID 34123074 DOI: 10.1039/d0sc02794d  0.329
2020 Ast J, Arvaniti A, Fine NHF, Nasteska D, Ashford FB, Stamataki Z, Koszegi Z, Bacon A, Jones BJ, Lucey MA, Sasaki S, Brierley DI, Hastoy B, Tomas A, D'Agostino G, ... ... Broichhagen J, et al. Author Correction: Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics. Nature Communications. 11: 5160. PMID 33037231 DOI: 10.1038/s41467-020-19101-4  0.529
2020 Hinnah K, Willems S, Morstein J, Heering J, Hartrampf F, Broichhagen J, Leippe P, Merk D, Trauner D. Photohormones Enable Optical Control of the Peroxisome Proliferator-Activated Receptor Gamma (PPAR). Journal of Medicinal Chemistry. PMID 32886507 DOI: 10.1021/Acs.Jmedchem.0C00654  0.427
2020 Pickford P, Lucey M, Fang Z, Bitsi S, de la Serna JB, Broichhagen J, Hodson DJ, Minnion J, Rutter GA, Bloom SR, Tomas A, Jones B. Signalling, trafficking and glucoregulatory properties of glucagon-like peptide-1 receptor agonists exendin-4 and lixisenatide. British Journal of Pharmacology. PMID 32436216 DOI: 10.1111/Bph.15134  0.363
2020 Fang Z, Chen S, Pickford P, Broichhagen J, Hodson DJ, Corrêa IR, Kumar S, Görlitz F, Dunsby C, French PMW, Rutter GA, Tan T, Bloom SR, Tomas A, Jones B. The Influence of Peptide Context on Signaling and Trafficking of Glucagon-like Peptide-1 Receptor Biased Agonists. Acs Pharmacology & Translational Science. 3: 345-360. PMID 32296773 DOI: 10.1021/acsptsci.0c00022  0.3
2020 Ast J, Arvaniti A, Fine NHF, Nasteska D, Ashford FB, Stamataki Z, Koszegi Z, Bacon A, Jones BJ, Lucey MA, Sasaki S, Brierley DI, Hastoy B, Tomas A, D'Agostino G, ... ... Broichhagen J, et al. Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics. Nature Communications. 11: 467. PMID 31980626 DOI: 10.1038/S41467-020-14309-W  0.612
2020 Poc P, Gutzeit VA, Ast J, Lee J, Jones BJ, D'Este E, Mathes B, Lehmann M, Hodson DJ, Levitz J, Broichhagen J. Interrogating surface versus intracellular transmembrane receptor populations using cell-impermeable SNAP-tag substrates Chemical Science. 11: 7871-7883. DOI: 10.1039/D0Sc02794D  0.377
2019 Leippe P, Broichhagen J, Cailliau K, Mougel A, Morel M, Dissous C, Vicogne J, Trauner D. Transformation of Receptor Tyrosine Kinases into Glutamate Receptors and Photoreceptors. Angewandte Chemie (International Ed. in English). PMID 31872568 DOI: 10.1002/Anie.201915352  0.432
2019 Acosta-Ruiz A, Gutzeit VA, Skelly MJ, Meadows S, Lee J, Parekh P, Orr AG, Liston C, Pleil KE, Broichhagen J, Levitz J. Branched Photoswitchable Tethered Ligands Enable Ultra-efficient Optical Control and Detection of G Protein-Coupled Receptors In Vivo. Neuron. PMID 31784287 DOI: 10.1016/J.Neuron.2019.10.036  0.435
2019 Donthamsetti PC, Broichhagen J, Vyklicky V, Stanley C, Fu Z, Visel M, Levitz JL, Javitch JA, Trauner D, Isacoff EY. Genetically Targeted Optical Control of an Endogenous G Protein-Coupled Receptor. Journal of the American Chemical Society. PMID 31291105 DOI: 10.1021/Jacs.9B02895  0.442
2019 Acosta-Ruiz A, Broichhagen J, Levitz J. Optical Regulation of Class C GPCRs by Photoswitchable Orthogonal Remotely Tethered Ligands. Methods in Molecular Biology (Clifton, N.J.). 1947: 103-136. PMID 30969413 DOI: 10.1007/978-1-4939-9121-1_6  0.433
2018 Frank JA, Broichhagen J, Yushchenko DA, Trauner D, Schultz C, Hodson DJ. Optical tools for understanding the complexity of β-cell signalling and insulin release. Nature Reviews. Endocrinology. PMID 30356209 DOI: 10.1038/S41574-018-0105-2  0.322
2018 Farrants H, Gutzeit VA, Acosta Ruiz A, Trauner D, Johnsson K, Levitz J, Broichhagen J. SNAP-tagged nanobodies enable reversible optical control of a G protein-coupled receptor via a remotely tethered photoswitchable ligand. Acs Chemical Biology. PMID 30141622 DOI: 10.1021/Acschembio.8B00628  0.609
2018 Karch S, Broichhagen J, Schneider J, Böning D, Hartmann S, Schmid B, Tripal P, Palmisano R, Alzheimer C, Johnsson K, Huth T. A new fluorogenic small molecule labeling tool for surface diffusion analysis and advanced fluorescence imaging of β-site amyloid precursor protein (APP)-cleaving enzyme 1 based on silicone rhodamine: SiR-BACE1. Journal of Medicinal Chemistry. PMID 29939737 DOI: 10.1021/Acs.Jmedchem.8B00387  0.538
2018 Podewin T, Ast J, Broichhagen J, Fine NHF, Nasteska D, Leippe P, Gailer M, Buenaventura T, Kanda N, Jones BJ, M'Kadmi C, Baneres JL, Marie J, Tomas A, Trauner D, et al. Conditional and Reversible Activation of Class A and B G Protein-Coupled Receptors Using Tethered Pharmacology. Acs Central Science. 4: 166-179. PMID 29532016 DOI: 10.1021/Acscentsci.7B00237  0.435
2018 DuBay KH, Iwan K, Osorio-Planes L, Geissler PL, Groll M, Trauner D, Broichhagen J. A predictive approach for the optical control of carbonic anhydrase II activity. Acs Chemical Biology. PMID 29357237 DOI: 10.1021/Acschembio.7B00862  0.313
2017 Frank JA, Yushchenko DA, Fine NHF, Duca M, Citir M, Broichhagen J, Hodson DJ, Schultz C, Trauner D. Optical control of GPR40 signalling in pancreatic β-cells. Chemical Science. 8: 7604-7610. PMID 29568424 DOI: 10.1039/C7Sc01475A  0.357
2017 Glock P, Broichhagen J, Kretschmer S, Blumhardt P, Mücksch J, Trauner D, Schwille P. Optical control of protein pattern formation. Angewandte Chemie (International Ed. in English). PMID 29266672 DOI: 10.1002/Anie.201712002  0.324
2017 Berry MH, Holt A, Levitz J, Broichhagen J, Gaub BM, Visel M, Stanley C, Aghi K, Kim YJ, Trauner D, Flannery J, Isacoff EY. Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor. Nature Communications. 8: 1862. PMID 29192252 DOI: 10.1038/S41467-017-01990-7  0.348
2017 Jones BJ, Scopelliti R, Tomas A, Bloom SR, Hodson DJ, Broichhagen J. Potent Prearranged Positive Allosteric Modulators of the Glucagon-like Peptide-1 Receptor. Chemistryopen. 6: 501-505. PMID 28794944 DOI: 10.1002/Open.201700062  0.426
2017 Podewin T, Broichhagen J, Frost C, Groneberg D, Ast J, Meyer-Berg H, Fine NHF, Friebe A, Zacharias M, Hodson DJ, Trauner D, Hoffmann-Röder A. Optical control of a receptor-linked guanylyl cyclase using a photoswitchable peptidic hormone. Chemical Science. 8: 4644-4653. PMID 28626572 DOI: 10.1039/C6Sc05044A  0.43
2017 Levitz J, Broichhagen J, Leippe P, Konrad D, Trauner D, Isacoff EY. Dual optical control and mechanistic insights into photoswitchable group II and III metabotropic glutamate receptors. Proceedings of the National Academy of Sciences of the United States of America. PMID 28396447 DOI: 10.1073/Pnas.1619652114  0.447
2017 Mehta ZB, Johnston NR, Nguyen-Tu MS, Broichhagen J, Schultz P, Larner DP, Leclerc I, Trauner D, Rutter GA, Hodson DJ. Remote control of glucose homeostasis in vivo using photopharmacology. Scientific Reports. 7: 291. PMID 28331198 DOI: 10.1038/S41598-017-00397-0  0.319
2016 Johnston NR, Mitchell RK, Haythorne E, Pessoa MP, Semplici F, Ferrer J, Piemonti L, Marchetti P, Bugliani M, Bosco D, Berishvili E, Duncanson P, Watkinson M, Broichhagen J, Trauner D, et al. Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose. Cell Metabolism. PMID 27452146 DOI: 10.1016/J.Cmet.2016.06.020  0.306
2016 Broichhagen J, Johnston NR, von Ohlen Y, Meyer-Berg H, Jones BJ, Bloom SR, Rutter GA, Trauner D, Hodson DJ. Allosteric Optical Control of a Class B G-Protein-Coupled Receptor. Angewandte Chemie (International Ed. in English). PMID 27059784 DOI: 10.1002/Anie.201600957  0.454
2016 Broichhagen J, Johnston NR, von Ohlen Y, Meyer-Berg H, Jones BJ, Bloom SR, Rutter GA, Trauner D, Hodson DJ. Allosterische optische Steuerung eines Klasse-B-G-Protein-gekoppelten Rezeptors Angewandte Chemie. 128: 5961-5965. DOI: 10.1002/Ange.201600957  0.307
2015 Broichhagen J, Damijonaitis A, Levitz J, Sokol KR, Leippe P, Konrad D, Isacoff EY, Trauner D. Orthogonal Optical Control of a G Protein-Coupled Receptor with a SNAP-Tethered Photochromic Ligand. Acs Central Science. 1: 383-93. PMID 27162996 DOI: 10.1021/Acscentsci.5B00260  0.451
2015 Broichhagen J, Podewin T, Meyer-Berg H, von Ohlen Y, Johnston NR, Jones BJ, Bloom SR, Rutter GA, Hoffmann-Röder A, Hodson DJ, Trauner D. Optical Control of Insulin Secretion Using an Incretin Switch. Angewandte Chemie (International Ed. in English). PMID 26585495 DOI: 10.1002/Anie.201506384  0.386
2015 Broichhagen J, Frank JA, Trauner D. A Roadmap to Success in Photopharmacology. Accounts of Chemical Research. 48: 1947-60. PMID 26103428 DOI: 10.1021/Acs.Accounts.5B00129  0.349
2015 Broichhagen J, Frank JA, Johnston NR, Mitchell RK, Šmid K, Marchetti P, Bugliani M, Rutter GA, Trauner D, Hodson DJ. A red-shifted photochromic sulfonylurea for the remote control of pancreatic beta cell function. Chemical Communications (Cambridge, England). 51: 6018-21. PMID 25744824 DOI: 10.1039/C5Cc01224D  0.319
2015 Damijonaitis A, Broichhagen J, Urushima T, Hüll K, Nagpal J, Laprell L, Schönberger M, Woodmansee DH, Rafiq A, Sumser MP, Kummer W, Gottschalk A, Trauner D. AzoCholine Enables Optical Control of Alpha 7 Nicotinic Acetylcholine Receptors in Neural Networks. Acs Chemical Neuroscience. 6: 701-7. PMID 25741856 DOI: 10.1021/Acschemneuro.5B00030  0.321
2014 Broichhagen J, Schönberger M, Cork SC, Frank JA, Marchetti P, Bugliani M, Shapiro AM, Trapp S, Rutter GA, Hodson DJ, Trauner D. Optical control of insulin release using a photoswitchable sulfonylurea. Nature Communications. 5: 5116. PMID 25311795 DOI: 10.1038/Ncomms6116  0.321
2014 Broichhagen J, Trauner D. The in vivo chemistry of photoswitched tethered ligands. Current Opinion in Chemical Biology. 21: 121-7. PMID 25108802 DOI: 10.1016/J.Cbpa.2014.07.008  0.435
2014 Broichhagen J, Jurastow I, Iwan K, Kummer W, Trauner D. Optical control of acetylcholinesterase with a tacrine switch. Angewandte Chemie (International Ed. in English). 53: 7657-60. PMID 24895330 DOI: 10.1002/Anie.201403666  0.359
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