Year |
Citation |
Score |
2020 |
Markusic DM, Martino AT, Porada CD, VandenDriessche T. Immunology of Gene and Cell Therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 32023479 DOI: 10.1016/J.Ymthe.2020.01.024 |
0.355 |
|
2020 |
Martino AT, Markusic DM. Immune Response Mechanisms against AAV Vectors in Animal Models. Molecular Therapy. Methods & Clinical Development. 17: 198-208. PMID 31970198 DOI: 10.1016/J.Omtm.2019.12.008 |
0.43 |
|
2017 |
Herzog RW, Cooper M, Perrin GQ, Biswas M, Martino AT, Morel L, Terhorst C, Hoffman BE. Regulatory T cells and TLR9 activation shape antibody formation to a secreted transgene product in AAV muscle gene transfer. Cellular Immunology. PMID 28888664 DOI: 10.1016/J.Cellimm.2017.07.012 |
0.447 |
|
2016 |
Carrig S, Wopat MJ, Martino AT. 550. Developing an Optimal Insulin Augmentation Therapy to Improve AAV Gene Transfer to Skeletal Muscle and Liver in Mice Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)33358-5 |
0.342 |
|
2015 |
Carrig SM, Bijjiga E, Martino AT. 681. Increasing Insulin Activity During AAV (Adeno-Associated Virus) Administration to Muscle Improves Gene Transfer in Mice Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)34290-3 |
0.344 |
|
2014 |
Basner-Tschakarjan E, Bijjiga E, Martino AT. Pre-Clinical Assessment of Immune Responses to Adeno-Associated Virus (AAV) Vectors. Frontiers in Immunology. 5: 28. PMID 24570676 DOI: 10.3389/Fimmu.2014.00028 |
0.474 |
|
2014 |
Rogers GL, Martino AT, Zolotukhin I, Ertl HC, Herzog RW. Role of the vector genome and underlying factor IX mutation in immune responses to AAV gene therapy for hemophilia B. Journal of Translational Medicine. 12: 25. PMID 24460861 DOI: 10.1186/1479-5876-12-25 |
0.414 |
|
2013 |
Martino AT, Basner-Tschakarjan E, Markusic DM, Finn JD, Hinderer C, Zhou S, Ostrov DA, Srivastava A, Ertl HC, Terhorst C, High KA, Mingozzi F, Herzog RW. Engineered AAV vector minimizes in vivo targeting of transduced hepatocytes by capsid-specific CD8+ T cells. Blood. 121: 2224-33. PMID 23325831 DOI: 10.1182/Blood-2012-10-460733 |
0.395 |
|
2012 |
Markusic DM, Martino AT, Mingozzi F, High KA, Herzog RW. In Vivo Model to Evaluate Loss of Liver-Derived Factor IX Expression Caused by AAV Capsid-Specific CD8+ T Cells Blood. 120: 2046-2046. DOI: 10.1182/Blood.V120.21.2046.2046 |
0.422 |
|
2011 |
Martino AT, Herzog RW, Anegon I, Adjali O. Measuring immune responses to recombinant AAV gene transfer. Methods in Molecular Biology (Clifton, N.J.). 807: 259-72. PMID 22034034 DOI: 10.1007/978-1-61779-370-7_11 |
0.455 |
|
2011 |
Rogers GL, Martino AT, Aslanidi GV, Jayandharan GR, Srivastava A, Herzog RW. Innate Immune Responses to AAV Vectors. Frontiers in Microbiology. 2: 194. PMID 21954398 DOI: 10.3389/Fmicb.2011.00194 |
0.45 |
|
2011 |
Martino AT, Suzuki M, Markusic DM, Zolotukhin I, Ryals RC, Moghimi B, Ertl HC, Muruve DA, Lee B, Herzog RW. The genome of self-complementary adeno-associated viral vectors increases Toll-like receptor 9-dependent innate immune responses in the liver. Blood. 117: 6459-68. PMID 21474674 DOI: 10.1182/Blood-2010-10-314518 |
0.489 |
|
2011 |
Hoffman BE, Martino AT, Sack BK, Cao O, Liao G, Terhorst C, Herzog RW. Nonredundant roles of IL-10 and TGF-β in suppression of immune responses to hepatic AAV-factor IX gene transfer. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1263-72. PMID 21386826 DOI: 10.1038/Mt.2011.33 |
0.427 |
|
2011 |
Jayandharan GR, Aslanidi G, Martino AT, Jahn SC, Perrin GQ, Herzog RW, Srivastava A. Activation of the NF-kappaB pathway by adeno-associated virus (AAV) vectors and its implications in immune response and gene therapy. Proceedings of the National Academy of Sciences of the United States of America. 108: 3743-8. PMID 21321191 DOI: 10.1073/Pnas.1012753108 |
0.377 |
|
2011 |
Martino AT, Mueller C, Braag S, Cruz PE, Campbell-Thompson M, Jin S, Flotte TR. N-glycosylation augmentation of the cystic fibrosis epithelium improves Pseudomonas aeruginosa clearance. American Journal of Respiratory Cell and Molecular Biology. 44: 824-30. PMID 20693405 DOI: 10.1165/Rcmb.2009-0285Oc |
0.483 |
|
2010 |
Martino AT, Suzuki M, Markusic D, Zolotukhin I, Muruve DA, Lee B, Herzog RW. Self-Complementary AAV Vectors Cause a Substantially Heightened TLR9-Dependent Innate Immune Response In the Liver Blood. 116: 252-252. DOI: 10.1182/Blood.V116.21.252.252 |
0.492 |
|
2009 |
Martino AT, Nayak S, Hoffman BE, Cooper M, Liao G, Markusic DM, Byrne BJ, Terhorst C, Herzog RW. Tolerance induction to cytoplasmic beta-galactosidase by hepatic AAV gene transfer: implications for antigen presentation and immunotoxicity. Plos One. 4: e6376. PMID 19652717 DOI: 10.1371/Journal.Pone.0006376 |
0.447 |
|
2009 |
Liqun Wang R, McLaughlin T, Cossette T, Tang Q, Foust K, Campbell-Thompson M, Martino A, Cruz P, Loiler S, Mueller C, Flotte TR. Recombinant AAV serotype and capsid mutant comparison for pulmonary gene transfer of alpha-1-antitrypsin using invasive and noninvasive delivery. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 81-7. PMID 18941444 DOI: 10.1038/Mt.2008.217 |
0.383 |
|
2009 |
Mueller C, Braag SA, Martino AT, Tang Q, Campbell-Thompson M, Flotte TR. The pros and cons of immunomodulatory IL-10 gene therapy with recombinant AAV in a Cftr-/- -dependent allergy mouse model. Gene Therapy. 16: 172-83. PMID 18818669 DOI: 10.1038/Gt.2008.156 |
0.353 |
|
2008 |
Mueller C, Torrez D, Braag S, Martino A, Clarke T, Campbell-Thompson M, Flotte TR. Partial correction of the CFTR-dependent ABPA mouse model with recombinant adeno-associated virus gene transfer of truncated CFTR gene. The Journal of Gene Medicine. 10: 51-60. PMID 18023072 DOI: 10.1002/Jgm.1119 |
0.438 |
|
2005 |
Muller C, Braag SA, Martino A, Atkinson MA, Flotte TR. 1083. Systemic rAAV-CB-IL-10 Expression and Its Long Term Effects on CD4+CD25+ T Cell Populations Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.630 |
0.372 |
|
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