Ashley T. Martino, Ph.D. - Publications

Affiliations: 
2007 University of Florida, Gainesville, Gainesville, FL, United States 
Area:
Genetics, Molecular Biology, Microbiology Biology

21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Markusic DM, Martino AT, Porada CD, VandenDriessche T. Immunology of Gene and Cell Therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 32023479 DOI: 10.1016/J.Ymthe.2020.01.024  0.355
2020 Martino AT, Markusic DM. Immune Response Mechanisms against AAV Vectors in Animal Models. Molecular Therapy. Methods & Clinical Development. 17: 198-208. PMID 31970198 DOI: 10.1016/J.Omtm.2019.12.008  0.43
2017 Herzog RW, Cooper M, Perrin GQ, Biswas M, Martino AT, Morel L, Terhorst C, Hoffman BE. Regulatory T cells and TLR9 activation shape antibody formation to a secreted transgene product in AAV muscle gene transfer. Cellular Immunology. PMID 28888664 DOI: 10.1016/J.Cellimm.2017.07.012  0.447
2016 Carrig S, Wopat MJ, Martino AT. 550. Developing an Optimal Insulin Augmentation Therapy to Improve AAV Gene Transfer to Skeletal Muscle and Liver in Mice Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)33358-5  0.342
2015 Carrig SM, Bijjiga E, Martino AT. 681. Increasing Insulin Activity During AAV (Adeno-Associated Virus) Administration to Muscle Improves Gene Transfer in Mice Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)34290-3  0.344
2014 Basner-Tschakarjan E, Bijjiga E, Martino AT. Pre-Clinical Assessment of Immune Responses to Adeno-Associated Virus (AAV) Vectors. Frontiers in Immunology. 5: 28. PMID 24570676 DOI: 10.3389/Fimmu.2014.00028  0.474
2014 Rogers GL, Martino AT, Zolotukhin I, Ertl HC, Herzog RW. Role of the vector genome and underlying factor IX mutation in immune responses to AAV gene therapy for hemophilia B. Journal of Translational Medicine. 12: 25. PMID 24460861 DOI: 10.1186/1479-5876-12-25  0.414
2013 Martino AT, Basner-Tschakarjan E, Markusic DM, Finn JD, Hinderer C, Zhou S, Ostrov DA, Srivastava A, Ertl HC, Terhorst C, High KA, Mingozzi F, Herzog RW. Engineered AAV vector minimizes in vivo targeting of transduced hepatocytes by capsid-specific CD8+ T cells. Blood. 121: 2224-33. PMID 23325831 DOI: 10.1182/Blood-2012-10-460733  0.395
2012 Markusic DM, Martino AT, Mingozzi F, High KA, Herzog RW. In Vivo Model to Evaluate Loss of Liver-Derived Factor IX Expression Caused by AAV Capsid-Specific CD8+ T Cells Blood. 120: 2046-2046. DOI: 10.1182/Blood.V120.21.2046.2046  0.422
2011 Martino AT, Herzog RW, Anegon I, Adjali O. Measuring immune responses to recombinant AAV gene transfer. Methods in Molecular Biology (Clifton, N.J.). 807: 259-72. PMID 22034034 DOI: 10.1007/978-1-61779-370-7_11  0.455
2011 Rogers GL, Martino AT, Aslanidi GV, Jayandharan GR, Srivastava A, Herzog RW. Innate Immune Responses to AAV Vectors. Frontiers in Microbiology. 2: 194. PMID 21954398 DOI: 10.3389/Fmicb.2011.00194  0.45
2011 Martino AT, Suzuki M, Markusic DM, Zolotukhin I, Ryals RC, Moghimi B, Ertl HC, Muruve DA, Lee B, Herzog RW. The genome of self-complementary adeno-associated viral vectors increases Toll-like receptor 9-dependent innate immune responses in the liver. Blood. 117: 6459-68. PMID 21474674 DOI: 10.1182/Blood-2010-10-314518  0.489
2011 Hoffman BE, Martino AT, Sack BK, Cao O, Liao G, Terhorst C, Herzog RW. Nonredundant roles of IL-10 and TGF-β in suppression of immune responses to hepatic AAV-factor IX gene transfer. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1263-72. PMID 21386826 DOI: 10.1038/Mt.2011.33  0.427
2011 Jayandharan GR, Aslanidi G, Martino AT, Jahn SC, Perrin GQ, Herzog RW, Srivastava A. Activation of the NF-kappaB pathway by adeno-associated virus (AAV) vectors and its implications in immune response and gene therapy. Proceedings of the National Academy of Sciences of the United States of America. 108: 3743-8. PMID 21321191 DOI: 10.1073/Pnas.1012753108  0.377
2011 Martino AT, Mueller C, Braag S, Cruz PE, Campbell-Thompson M, Jin S, Flotte TR. N-glycosylation augmentation of the cystic fibrosis epithelium improves Pseudomonas aeruginosa clearance. American Journal of Respiratory Cell and Molecular Biology. 44: 824-30. PMID 20693405 DOI: 10.1165/Rcmb.2009-0285Oc  0.483
2010 Martino AT, Suzuki M, Markusic D, Zolotukhin I, Muruve DA, Lee B, Herzog RW. Self-Complementary AAV Vectors Cause a Substantially Heightened TLR9-Dependent Innate Immune Response In the Liver Blood. 116: 252-252. DOI: 10.1182/Blood.V116.21.252.252  0.492
2009 Martino AT, Nayak S, Hoffman BE, Cooper M, Liao G, Markusic DM, Byrne BJ, Terhorst C, Herzog RW. Tolerance induction to cytoplasmic beta-galactosidase by hepatic AAV gene transfer: implications for antigen presentation and immunotoxicity. Plos One. 4: e6376. PMID 19652717 DOI: 10.1371/Journal.Pone.0006376  0.447
2009 Liqun Wang R, McLaughlin T, Cossette T, Tang Q, Foust K, Campbell-Thompson M, Martino A, Cruz P, Loiler S, Mueller C, Flotte TR. Recombinant AAV serotype and capsid mutant comparison for pulmonary gene transfer of alpha-1-antitrypsin using invasive and noninvasive delivery. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 81-7. PMID 18941444 DOI: 10.1038/Mt.2008.217  0.383
2009 Mueller C, Braag SA, Martino AT, Tang Q, Campbell-Thompson M, Flotte TR. The pros and cons of immunomodulatory IL-10 gene therapy with recombinant AAV in a Cftr-/- -dependent allergy mouse model. Gene Therapy. 16: 172-83. PMID 18818669 DOI: 10.1038/Gt.2008.156  0.353
2008 Mueller C, Torrez D, Braag S, Martino A, Clarke T, Campbell-Thompson M, Flotte TR. Partial correction of the CFTR-dependent ABPA mouse model with recombinant adeno-associated virus gene transfer of truncated CFTR gene. The Journal of Gene Medicine. 10: 51-60. PMID 18023072 DOI: 10.1002/Jgm.1119  0.438
2005 Muller C, Braag SA, Martino A, Atkinson MA, Flotte TR. 1083. Systemic rAAV-CB-IL-10 Expression and Its Long Term Effects on CD4+CD25+ T Cell Populations Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.630  0.372
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