James L. Riley - Related publications

University of Pennsylvania Medical School, Philadelphia, PA, United States 
 1989 Vanderbilt University, Nashville, TN 
 1994 Emory University, Atlanta, GA 
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 FitzPatrick MEB, Provine NM, Garner LC, Powell K, Amini A, Irwin SL, Ferry H, Ambrose T, Friend P, Vrakas G, Reddy S, Soilleux E, Klenerman P, Allan PJ. Human intestinal tissue-resident memory T cells comprise transcriptionally and functionally distinct subsets. Cell Reports. 34: 108661. PMID 33472060 DOI: 10.1016/j.celrep.2020.108661   
2021 Richardson JR, Schöllhorn A, Gouttefangeas C, Schuhmacher J. CD4+ T Cells: Multitasking Cells in the Duty of Cancer Immunotherapy. Cancers. 13. PMID 33546283 DOI: 10.3390/cancers13040596   
2021 Kervevan J, Chakrabarti LA. Role of CD4+ T Cells in the Control of Viral Infections: Recent Advances and Open Questions. International Journal of Molecular Sciences. 22. PMID 33430234 DOI: 10.3390/ijms22020523   
2021 Peng Q, Zhu X, Li C, Xin P, Zheng Y, Liu S. APDL1-CART cells exhibit strong PD-L1-specific activity against leukemia cells. Aging. 13. PMID 33653969 DOI: 10.18632/aging.202578   
2021 Dong C. Cytokine Regulation and Function in T Cells. Annual Review of Immunology. PMID 33428453 DOI: 10.1146/annurev-immunol-061020-053702   
2021 Li L, Shi W, Liu M, Bai X, Sun Y, Zhu X, Su H, Ji Y, Zhu F, Liu X, Luo Y, Liu T, Lin B, Lu Y. Single-Cell Secretion Analysis in the Engineered Tumor Microenvironment Reveals Differential Modulation of Macrophage Immune Responses. Analytical Chemistry. PMID 33636079 DOI: 10.1021/acs.analchem.0c04604   
2021 Hanna SJ, Codd AS, Gea-Mallorqui E, Scourfield DO, Richter FC, Ladell K, Borsa M, Compeer EB, Moon OR, Galloway SAE, Dimonte S, Capitani L, Shepherd FR, Wilson JD, Uhl LFK, , et al. T cell phenotypes in COVID-19 - a living review. Oxford Open Immunology. 2: iqaa007. PMID 33575657 DOI: 10.1093/oxfimm/iqaa007   
2021 Yoshida Y, Mikami N, Nakanishi Y, Saimoto M, Nagaike A, Shimono H, Nakano S, Tsuji T, Kohno T. Characterization of an expanded IL-10-producing-suppressive T cell population associated with immune tolerance. Biological & Pharmaceutical Bulletin. PMID 33504740 DOI: 10.1248/bpb.b19-01072   
2021 Son YM, Cheon IS, Wu Y, Li C, Wang Z, Gao X, Chen Y, Takahashi Y, Fu YX, Dent AL, Kaplan MH, Taylor JJ, Cui W, Sun J. Tissue-resident CD4 T helper cells assist the development of protective respiratory B and CD8 T cell memory responses. Science Immunology. 6. PMID 33419791 DOI: 10.1126/sciimmunol.abb6852   
2021 Li Y, Tunbridge HM, Britton GJ, Hill EV, Sinai P, Cirillo S, Thompson C, Fallah-Arani F, Dovedi SJ, Wraith DC, Wülfing C. A LAT-Based Signaling Complex in the Immunological Synapse as Determined with Live Cell Imaging Is Less Stable in T Cells with Regulatory Capability. Cells. 10. PMID 33671236 DOI: 10.3390/cells10020418   
2021 Kushnareva Y, Mathews IT, Andreyev AY, Altay G, Lindestam Arlehamn CS, Pandurangan V, Nilsson R, Jain M, Sette A, Peters B, Sharma S. Functional Analysis of Immune Signature Genes in Th1* Memory Cells Links ISOC1 and Pyrimidine Metabolism to IFN-γ and IL-17 Production. Journal of Immunology (Baltimore, Md. : 1950). PMID 33547171 DOI: 10.4049/jimmunol.2000672   
2021 Paul S, Pearlman AH, Douglass J, Mog BJ, Hsiue EH, Hwang MS, DiNapoli SR, Konig MF, Brown PA, Wright KM, Sur S, Gabelli SB, Li Y, Ghiaur G, Pardoll D, et al. TCR beta chain-directed bispecific antibodies for the treatment of T-cell cancers. Science Translational Medicine. PMID 33649188 DOI: 10.1126/scitranslmed.abd3595   
2021 Paul S, Pearlman AH, Douglass J, Mog BJ, Hsiue EH, Hwang MS, DiNapoli SR, Konig MF, Brown PA, Wright KM, Sur S, Gabelli SB, Li Y, Ghiaur G, Pardoll D, et al. TCR beta chain-directed bispecific antibodies for the treatment of T-cell cancers. Science Translational Medicine. PMID 33649188 DOI: 10.1126/scitranslmed.abd3595   
2021 Guo YE, Li Y, Cai B, He Q, Chen G, Wang M, Wang K, Wan X, Yan Q. Phenotyping of immune and endometrial epithelial cells in endometrial carcinomas revealed by single-cell RNA sequencing. Aging. 12. PMID 33429363 DOI: 10.18632/aging.202288   
2021 Gherardin NA, Waldeck K, Caneborg A, Martelotto LG, Balachander S, Zethoven M, Petrone PM, Pattison A, Wilmott JS, Quiñones-Parra SM, Rossello F, Posner A, Wong A, Weppler AM, Shannon KF, et al. γδ T cells in Merkel cell carcinomas have a proinflammatory profile prognostic of patient survival. Cancer Immunology Research. PMID 33674358 DOI: 10.1158/2326-6066.CIR-20-0817   
2021 Jaiswal H, Ciucci T, Wang H, Tang W, Claudio E, Murphy PM, Bosselut R, Siebenlist U. The NF-κB regulator Bcl-3 restricts terminal differentiation and promotes memory cell formation of CD8+ T cells during viral infection. Plos Pathogens. 17: e1009249. PMID 33508001 DOI: 10.1371/journal.ppat.1009249   
2021 Wagner AK, Gehrmann U, Hiltbrunner S, Carannante V, Luu TT, Näslund TI, Brauner H, Kadri N, Kärre K, Gabrielsson S. Soluble and Exosome-Bound α-Galactosylceramide Mediate Preferential Proliferation of Educated NK Cells with Increased Anti-Tumor Capacity. Cancers. 13. PMID 33467442 DOI: 10.3390/cancers13020298   
2021 Li F, Chen Y, Pang M, Yang P, Jing H. Immune Checkpoint Inhibitors and Cellular Treatment for Lymphoma Immunotherapy. Clinical and Experimental Immunology. PMID 33675535 DOI: 10.1111/cei.13592   
2021 Wang X, Cabrera FG, Sharp KL, Spencer DM, Foster AE, Bayle JH. Engineering Tolerance toward Allogeneic CAR-T Cells by Regulation of MHC Surface Expression with Human Herpes Virus-8 Proteins. Molecular Therapy : the Journal of the American Society of Gene Therapy. 29: 718-733. PMID 33554868 DOI: 10.1016/j.ymthe.2020.10.019   
2021 Seo W, Jerin C, Nishikawa H. Transcriptional regulatory network for the establishment of CD8 T cell exhaustion. Experimental & Molecular Medicine. PMID 33627794 DOI: 10.1038/s12276-021-00568-0   
2021 Goodier MR, Riley EM. Regulation of the human NK cell compartment by pathogens and vaccines. Clinical & Translational Immunology. 10: e1244. PMID 33505682 DOI: 10.1002/cti2.1244   
2021 Cachot A, Bilous M, Liu YC, Li X, Saillard M, Cenerenti M, Rockinger GA, Wyss T, Guillaume P, Schmidt J, Genolet R, Ercolano G, Protti MP, Reith W, Ioannidou K, et al. Tumor-specific cytolytic CD4 T cells mediate immunity against human cancer. Science Advances. 7. PMID 33637530 DOI: 10.1126/sciadv.abe3348   
2021 Cachot A, Bilous M, Liu YC, Li X, Saillard M, Cenerenti M, Rockinger GA, Wyss T, Guillaume P, Schmidt J, Genolet R, Ercolano G, Protti MP, Reith W, Ioannidou K, et al. Tumor-specific cytolytic CD4 T cells mediate immunity against human cancer. Science Advances. 7. PMID 33637530 DOI: 10.1126/sciadv.abe3348   
2021 Zhai X, You F, Xiang S, Jiang L, Chen D, Li Y, Fan S, Han Z, Zhang T, An G, Zhang B, Chen Y, Meng H, Yang L. MUC1-Tn-targeting chimeric antigen receptor-modified Vγ9Vδ2 T cells with enhanced antigen-specific anti-tumor activity. American Journal of Cancer Research. 11: 79-91. PMID 33520361   
2021 Janelle V, Delisle JS. T-Cell Dysfunction as a Limitation of Adoptive Immunotherapy: Current Concepts and Mitigation Strategies. Cancers. 13. PMID 33546277 DOI: 10.3390/cancers13040598   
2021 Jang E, Cho S, Pyo S, Nam JW, Youn J. An Inflammatory Loop Between Spleen-Derived Myeloid Cells and CD4 T Cells Leads to Accumulation of Long-Lived Plasma Cells That Exacerbates Lupus Autoimmunity. Frontiers in Immunology. 12: 631472. PMID 33643317 DOI: 10.3389/fimmu.2021.631472   
2021 de Araújo ND, Gama FM, de Souza Barros M, Ribeiro TLP, Alves FS, Xabregas LA, Tarragô AM, Malheiro A, Costa AG. Translating Unconventional T Cells and Their Roles in Leukemia Antitumor Immunity. Journal of Immunology Research. 2021: 6633824. PMID 33506055 DOI: 10.1155/2021/6633824   
2021 Freen-van Heeren JJ. Using CRISPR to enhance T cell effector function for therapeutic applications. Cytokine: X. 3: 100049. PMID 33604565 DOI: 10.1016/j.cytox.2020.100049   
2021 Lee JH, Hu JK, Georgeson E, Nakao C, Groschel B, Dileepan T, Jenkins MK, Seumois G, Vijayanand P, Schief WR, Crotty S. Modulating the quantity of HIV Env-specific CD4 T cell help promotes rare B cell responses in germinal centers. The Journal of Experimental Medicine. 218. PMID 33355623 DOI: 10.1084/jem.20201254   
2021 Zhong R, Zhang Y, Chen D, Cao S, Han B, Zhong H. Single-cell RNA sequencing reveals cellular and molecular immune profile in a Pembrolizumab-responsive PD-L1-negative lung cancer patient. Cancer Immunology, Immunotherapy : Cii. PMID 33506299 DOI: 10.1007/s00262-021-02848-0   
2021 Guo J, Mu D, Han Y. [Research Progress on the Mechanism and Clinical Data of Cereblon 
in Reversing the Resistance of Lung Cancer to PD-1 Antibody by T cells]. Zhongguo Fei Ai Za Zhi = Chinese Journal of Lung Cancer. 24: 49-55. PMID 33478191 DOI: 10.3779/j.issn.1009-3419.2020.102.49   
2021 Wei J, Zheng W, Chapman NM, Geiger TL, Chi H. T cell metabolism in homeostasis and cancer immunity. Current Opinion in Biotechnology. 68: 240-250. PMID 33676144 DOI: 10.1016/j.copbio.2021.02.003   
2021 Moore TV, Scurti GM, DeJong M, Wang SY, Dalheim AV, Wagner CR, Hutchens KA, Speiser JJ, Godellas CV, Fountain C, Fleser J, Moudgil T, Thomas M, Murray D, Curti BD, et al. HDAC inhibition prevents transgene expression downregulation and loss-of-function in T-cell-receptor-transduced T cells. Molecular Therapy Oncolytics. 20: 352-363. PMID 33614916 DOI: 10.1016/j.omto.2021.01.014   
2021 Lehmann AA, Reche PA, Zhang T, Suwansaard M, Lehmann PV. CERI, CEFX, and CPI: Largely Improved Positive Controls for Testing Antigen-Specific T Cell Function in PBMC Compared to CEF. Cells. 10. PMID 33514016 DOI: 10.3390/cells10020248   
2021 Trefzer A, Kadam P, Wang SH, Pennavaria S, Lober B, Akçabozan B, Kranich J, Brocker T, Nakano N, Irmler M, Beckers J, Straub T, Obst R. Dynamic adoption of anergy by antigen-exhausted CD4 T cells. Cell Reports. 34: 108748. PMID 33567282 DOI: 10.1016/j.celrep.2021.108748   
2021 Zhang S, Springer LE, Rao HZ, Espinosa Trethewy RG, Bishop LM, Hancock MH, Grey F, Snyder CM. Hematopoietic cell-mediated dissemination of murine cytomegalovirus is regulated by NK cells and immune evasion. Plos Pathogens. 17: e1009255. PMID 33508041 DOI: 10.1371/journal.ppat.1009255   
2021 Park J, Shin Y, Kim JM, Kweon S, Song AY, Baek Y, Kim J, Cho D, Kim HS, Doh J. Multifunctional Microparticles with Stimulation and Sensing Capabilities for Facile NK Cell Activity Assay. Acs Sensors. PMID 33606518 DOI: 10.1021/acssensors.0c02138   
2021 Riedel JH, Turner JE, Panzer U. T helper cell trafficking in autoimmune kidney diseases. Cell and Tissue Research. PMID 33598825 DOI: 10.1007/s00441-020-03403-6   
2021 Farley CR, Morris AB, Tariq M, Bennion KB, Potdar S, Kudchadkar R, Lowe MC, Ford ML. FcγRIIB is a T cell checkpoint in antitumor immunity. Jci Insight. 6. PMID 33616086 DOI: 10.1172/jci.insight.135623   
2021 Naghizadeh M, Hatamzade N, Larsen FT, Kjaerup RB, Wattrang E, Dalgaard TS. Kinetics of activation marker expression after in vitro polyclonal stimulation of chicken peripheral T cells. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. PMID 33455046 DOI: 10.1002/cyto.a.24304   
2021 Herda S, Heimann A, Obermayer B, Ciraolo E, Althoff S, Ruß J, Grunert C, Busse A, Bullinger L, Pezzutto A, Blankenstein T, Beule D, Na IK. Long-term in vitro expansion ensures increased yield of central memory T cells as perspective for manufacturing challenges. International Journal of Cancer. PMID 33600609 DOI: 10.1002/ijc.33523   
2021 Chen J, Yang J, Li H, Yang Z, Zhang X, Li X, Wang J, Zhang Y, Chen S, Song M. Single-cell transcriptomics reveal the intratumoral landscape of infiltrated T cell subpopulations in oral squamous cell carcinoma. Molecular Oncology. PMID 33513276 DOI: 10.1002/1878-0261.12910   
2021 Alzubi J, Lock D, Rhiel M, Schmitz S, Wild S, Mussolino C, Hildenbeutel M, Brandes C, Rositzka J, Lennartz S, Haas SA, Chmielewski KO, Schaser T, Kaiser A, Cathomen T, et al. Automated generation of gene-edited CAR T cells at clinical scale. Molecular Therapy. Methods & Clinical Development. 20: 379-388. PMID 33575430 DOI: 10.1016/j.omtm.2020.12.008   
2021 Wang S, Li H, Zhang F, Jiao Y, Xie Q, Zhang Z, Li X. Expression of TIGIT in splenic and circulatory T cells from mice acutely infected with Toxoplasma gondii. Parasite (Paris, France). 28: 13. PMID 33629951 DOI: 10.1051/parasite/2021010   
2021 Kritikou JS, Oliveira MM, Record J, Saeed MB, Nigam SM, He M, Keszei M, Wagner AK, Brauner H, Sendel A, Sedimbi SK, Rentouli S, Lane DP, Snapper SB, Kärre K, et al. Constitutive WASp activation leads to abnormal cytotoxic cells with increased response against tumors. Jci Insight. PMID 33621210 DOI: 10.1172/jci.insight.140273   
2021 Subburayalu J, Dolff S, Xu S, Sun M, Lindemann M, Heinold A, Heinemann FM, Tervaert JWC, Eisenberger U, Korth J, Brinkhoff A, Kribben A, Witzke O, Wilde B. Characterization of follicular T helper cells and donor-specific T helper cells in renal transplant patients with de novo donor-specific HLA-antibodies. Clinical Immunology (Orlando, Fla.). 108698. PMID 33639275 DOI: 10.1016/j.clim.2021.108698   
2021 Rosenstock P, Kaufmann T. Sialic Acids and Their Influence on Human NK Cell Function. Cells. 10. PMID 33572710 DOI: 10.3390/cells10020263   
2021 Zhou Y, Cheng JT, Feng ZX, Wang YY, Zhang Y, Cai WQ, Han ZW, Wang XW, Xiang Y, Yang HY, Liu BR, Peng XC, Cui SZ, Xin HW. Could gastrointestinal tumor-initiating cells originate from cell-cell fusion ? World Journal of Gastrointestinal Oncology. 13: 92-108. PMID 33643526 DOI: 10.4251/wjgo.v13.i2.92   
2021 Xiong K, Niu J, Zheng R, Liu Z, Song Y, Wang L, Zhu C, Fan L. The Role of -Catenin in Th1 Immune Response against Tuberculosis and Profiles of Expression in Patients with Pulmonary Tuberculosis. Journal of Immunology Research. 2021: 6625855. PMID 33628846 DOI: 10.1155/2021/6625855   
2021 van der Horst HJ, de Jonge AV, Hiemstra IH, Gelderloos AT, Berry DRAI, Hijmering NJ, van Essen HF, de Jong D, Chamuleau MED, Zweegman S, Breij ECW, Roemer MGM, Mutis T. Epcoritamab induces potent anti-tumor activity against malignant B-cells from patients with DLBCL, FL and MCL, irrespective of prior CD20 monoclonal antibody treatment. Blood Cancer Journal. 11: 38. PMID 33602901 DOI: 10.1038/s41408-021-00430-6