| Year |
Citation |
Score |
| 2017 |
Liu Y, Guardia-Laguarta C, Yin J, Erdjument-Bromage H, Martin B, James M, Jiang X, Przedborski S. The Ubiquitination of PINK1 Is Restricted to Its Mature 52-kDa Form. Cell Reports. 20: 30-39. PMID 28683321 DOI: 10.1016/J.Celrep.2017.06.022 |
0.31 |
|
| 2015 |
Baral PK, Swayampakula M, Aguzzi A, James MN. X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins. Journal of Structural Biology. 192: 37-47. PMID 26320075 DOI: 10.1016/J.Jsb.2015.08.014 |
0.342 |
|
| 2014 |
Baral PK, Swayampakula M, Rout MK, Kav NN, Spyracopoulos L, Aguzzi A, James MN. Structural basis of prion inhibition by phenothiazine compounds. Structure (London, England : 1993). 22: 291-303. PMID 24373770 DOI: 10.1016/J.Str.2013.11.009 |
0.373 |
|
| 2014 |
Jacobson JM, Yin J, Kitov PI, Mulvey G, Griener TP, James MN, Armstrong G, Bundle DR. The crystal structure of shiga toxin type 2 with bound disaccharide guides the design of a heterobifunctional toxin inhibitor. The Journal of Biological Chemistry. 289: 885-94. PMID 24225957 DOI: 10.1074/Jbc.M113.518886 |
0.374 |
|
| 2014 |
Baral P, Swayampakula M, Rout M, Spyracopoulos L, Aguzzi A, James M. Structural Basis of Prion Protein Conformation Conversion Inhibition Acta Crystallographica Section a Foundations and Advances. 70: C812-C812. DOI: 10.1107/S2053273314091876 |
0.4 |
|
| 2013 |
Bie H, Yin J, He X, Kermode AR, Goddard-Borger ED, Withers SG, James MN. Insights into mucopolysaccharidosis I from the structure and action of α-L-iduronidase. Nature Chemical Biology. 9: 739-45. PMID 24036510 DOI: 10.1038/Nchembio.1357 |
0.426 |
|
| 2013 |
Jacob-Ferreira AL, Kondo MY, Baral PK, James MN, Holt A, Fan X, Schulz R. Phosphorylation status of 72 kDa MMP-2 determines its structure and activity in response to peroxynitrite. Plos One. 8: e71794. PMID 24013357 DOI: 10.1371/Journal.Pone.0071794 |
0.322 |
|
| 2013 |
Sonati T, Reimann RR, Falsig J, Baral PK, O'Connor T, Hornemann S, Yaganoglu S, Li B, Herrmann US, Wieland B, Swayampakula M, Rahman MH, Das D, Kav N, Riek R, ... ... James MN, et al. The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein. Nature. 501: 102-6. PMID 23903654 DOI: 10.1038/Nature12402 |
0.34 |
|
| 2013 |
Swayampakula M, Baral PK, Aguzzi A, Kav NN, James MN. The crystal structure of an octapeptide repeat of the prion protein in complex with a Fab fragment of the POM2 antibody. Protein Science : a Publication of the Protein Society. 22: 893-903. PMID 23629842 DOI: 10.1002/Pro.2270 |
0.439 |
|
| 2013 |
Skene-Arnold TD, Luu HA, Uhrig RG, De Wever V, Nimick M, Maynes J, Fong A, James MN, Trinkle-Mulcahy L, Moorhead GB, Holmes CF. Molecular mechanisms underlying the interaction of protein phosphatase-1c with ASPP proteins. The Biochemical Journal. 449: 649-59. PMID 23088536 DOI: 10.1042/Bj20120506 |
0.687 |
|
| 2012 |
Baral PK, Wieland B, Swayampakula M, Polymenidou M, Rahman MH, Kav NN, Aguzzi A, James MN. Structural studies on the folded domain of the human prion protein bound to the Fab fragment of the antibody POM1. Acta Crystallographica. Section D, Biological Crystallography. 68: 1501-12. PMID 23090399 DOI: 10.1107/S0907444912037328 |
0.368 |
|
| 2012 |
Baretta K, Garen C, Yin J, James MN. Expression, purification, crystallization and preliminary crystallographic analysis of the phosphoglycerate kinase from Acinetobacter baumannii. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 68: 790-2. PMID 22750866 DOI: 10.1107/S1744309112020222 |
0.305 |
|
| 2012 |
Cherney MM, Zhang Y, James MN, Weiner JH. Structure-activity characterization of sulfide:quinone oxidoreductase variants. Journal of Structural Biology. 178: 319-28. PMID 22542586 DOI: 10.1016/J.Jsb.2012.04.007 |
0.403 |
|
| 2011 |
Niu C, Yin J, Cherney MM, James MN. Expression, purification and preliminary crystallographic analysis of Rv2247, the β subunit of acyl-CoA carboxylase (ACCD6) from Mycobacterium tuberculosis. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1637-40. PMID 22139186 DOI: 10.1107/S1744309111038413 |
0.332 |
|
| 2011 |
Baral PK, Wieland B, Swayampakula M, Polymenidou M, Aguzzi A, Kav NN, James MN. Crystallization and preliminary X-ray diffraction analysis of prion protein bound to the Fab fragment of the POM1 antibody. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1211-3. PMID 22102029 DOI: 10.1107/S1744309111026273 |
0.389 |
|
| 2011 |
Cherney MM, Cherney LT, Garen CR, James MN. The structures of Thermoplasma volcanium phosphoribosyl pyrophosphate synthetase bound to ribose-5-phosphate and ATP analogs. Journal of Molecular Biology. 413: 844-56. PMID 21963988 DOI: 10.1016/J.Jmb.2011.09.007 |
0.438 |
|
| 2011 |
Yin J, Garen CR, Bateman K, Yu M, Lyon EZ, Habel J, Kim H, Hung LW, Kim CY, James MN. Expression, purification and preliminary crystallographic analysis of O-acetylhomoserine sulfhydrylase from Mycobacterium tuberculosis. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 959-63. PMID 21821905 DOI: 10.1107/S1744309111017611 |
0.344 |
|
| 2011 |
Yin J, Garen G, Garen C, James MN. Expression, purification and preliminary crystallographic analysis of Rv3002c, the regulatory subunit of acetolactate synthase (IlvH) from Mycobacterium tuberculosis. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 933-6. PMID 21821899 DOI: 10.1107/S1744309111021105 |
0.342 |
|
| 2011 |
Watanabe N, Clay MD, van Belkum MJ, Fan C, Vederas JC, James MN. The structure of LL-diaminopimelate aminotransferase from Chlamydia trachomatis: implications for its broad substrate specificity. Journal of Molecular Biology. 411: 649-60. PMID 21722650 DOI: 10.1016/J.Jmb.2011.06.023 |
0.479 |
|
| 2011 |
Krishnaswamy S, Baral PK, James MN, Kav NN. Site-directed mutagenesis of histidine 69 and glutamic acid 148 alters the ribonuclease activity of pea ABR17 (PR10.4). Plant Physiology and Biochemistry : Ppb / SociéTé FrançAise De Physiologie VéGéTale. 49: 958-62. PMID 21600779 DOI: 10.1016/J.Plaphy.2010.10.010 |
0.384 |
|
| 2011 |
Watanabe N, James MN. Structural insights for the substrate recognition mechanism of LL-diaminopimelate aminotransferase. Biochimica Et Biophysica Acta. 1814: 1528-33. PMID 21435399 DOI: 10.1016/J.Bbapap.2011.03.008 |
0.429 |
|
| 2011 |
Bateman KS, James MN. Plant protein proteinase inhibitors: structure and mechanism of inhibition. Current Protein & Peptide Science. 12: 340-7. PMID 21418022 DOI: 10.2174/138920311796391124 |
0.435 |
|
| 2011 |
Bateman KS, Cherney MM, Mahuran DJ, Tropak M, James MN. Crystal structure of β-hexosaminidase B in complex with pyrimethamine, a potential pharmacological chaperone. Journal of Medicinal Chemistry. 54: 1421-9. PMID 21265544 DOI: 10.1021/Jm101443U |
0.429 |
|
| 2011 |
Chim N, Habel JE, Johnston JM, Krieger I, Miallau L, Sankaranarayanan R, Morse RP, Bruning J, Swanson S, Kim H, Kim CY, Li H, Bulloch EM, Payne RJ, Manos-Turvey A, ... ... James MN, et al. The TB Structural Genomics Consortium: a decade of progress. Tuberculosis (Edinburgh, Scotland). 91: 155-72. PMID 21247804 DOI: 10.1016/J.Tube.2010.11.009 |
0.499 |
|
| 2011 |
Cherney MM, Lecaille F, Kienitz M, Nallaseth FS, Li Z, James MN, Brömme D. Structure-activity analysis of cathepsin K/chondroitin 4-sulfate interactions. The Journal of Biological Chemistry. 286: 8988-98. PMID 21193413 DOI: 10.1074/Jbc.M110.126706 |
0.405 |
|
| 2010 |
Boland MP, Hatty CR, Separovic F, Hill AF, Tew DJ, Barnham KJ, Haigh CL, James M, Masters CL, Collins SJ. Anionic phospholipid interactions of the prion protein N terminus are minimally perturbing and not driven solely by the octapeptide repeat domain. The Journal of Biological Chemistry. 285: 32282-92. PMID 20679345 DOI: 10.1074/Jbc.M110.123398 |
0.346 |
|
| 2010 |
Kondo MY, Okamoto DN, Santos JA, Juliano MA, Oda K, Pillai B, James MN, Juliano L, Gouvea IE. Studies on the catalytic mechanism of a glutamic peptidase. The Journal of Biological Chemistry. 285: 21437-45. PMID 20442413 DOI: 10.1074/Jbc.M110.122432 |
0.377 |
|
| 2010 |
Cherney LT, Cherney MM, Garen CR, James MN. Crystal structure of the intermediate complex of the arginine repressor from Mycobacterium tuberculosis bound with its DNA operator reveals detailed mechanism of arginine repression. Journal of Molecular Biology. 399: 240-54. PMID 20382162 DOI: 10.1016/J.Jmb.2010.03.065 |
0.422 |
|
| 2010 |
Cherney MM, Zhang Y, Solomonson M, Weiner JH, James MN. Crystal structure of sulfide:quinone oxidoreductase from Acidithiobacillus ferrooxidans: insights into sulfidotrophic respiration and detoxification. Journal of Molecular Biology. 398: 292-305. PMID 20303979 DOI: 10.1016/J.Jmb.2010.03.018 |
0.465 |
|
| 2010 |
Sankaranarayanan R, Cherney MM, Garen C, Garen G, Niu C, Yuan M, James MN. The molecular structure of ornithine acetyltransferase from Mycobacterium tuberculosis bound to ornithine, a competitive inhibitor. Journal of Molecular Biology. 397: 979-90. PMID 20184895 DOI: 10.1016/J.Jmb.2010.02.018 |
0.503 |
|
| 2010 |
McPhalen CA, Svendsen I, Jonassen I, James MN. Crystal and molecular structure of chymotrypsin inhibitor 2 from barley seeds in complex with subtilisin Novo. Proceedings of the National Academy of Sciences of the United States of America. 82: 7242-6. PMID 16593622 DOI: 10.1073/PNAS.82.21.7242 |
0.404 |
|
| 2009 |
Zhang Y, Cherney MM, Solomonson M, Liu J, James MN, Weiner JH. Preliminary X-ray crystallographic analysis of sulfide:quinone oxidoreductase from Acidithiobacillus ferrooxidans. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 65: 839-42. PMID 19652354 DOI: 10.1107/S1744309109027535 |
0.371 |
|
| 2009 |
Cherney LT, Cherney MM, Garen CR, James MN. The structure of the arginine repressor from Mycobacterium tuberculosis bound with its DNA operator and Co-repressor, L-arginine. Journal of Molecular Biology. 388: 85-97. PMID 19265706 DOI: 10.1016/J.Jmb.2009.02.053 |
0.381 |
|
| 2009 |
Sankaranarayanan R, Garen CR, Cherney MM, Yuan M, Lee C, James MN. Preliminary X-ray crystallographic analysis of ornithine acetyltransferase (Rv1653) from Mycobacterium tuberculosis. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 65: 173-6. PMID 19194014 DOI: 10.1107/S1744309109000360 |
0.355 |
|
| 2009 |
Pillai B, Moorthie VA, van Belkum MJ, Marcus SL, Cherney MM, Diaper CM, Vederas JC, James MN. Crystal structure of diaminopimelate epimerase from Arabidopsis thaliana, an amino acid racemase critical for L-lysine biosynthesis. Journal of Molecular Biology. 385: 580-94. PMID 19013471 DOI: 10.1016/J.Jmb.2008.10.072 |
0.471 |
|
| 2008 |
Cherney LT, Cherney MM, Garen CR, Lu GJ, James MN. Crystal structure of the arginine repressor protein in complex with the DNA operator from Mycobacterium tuberculosis. Journal of Molecular Biology. 384: 1330-40. PMID 18952097 DOI: 10.1016/J.Jmb.2008.10.015 |
0.417 |
|
| 2008 |
Watanabe N, Clay MD, van Belkum MJ, Cherney MM, Vederas JC, James MN. Mechanism of substrate recognition and PLP-induced conformational changes in LL-diaminopimelate aminotransferase from Arabidopsis thaliana. Journal of Molecular Biology. 384: 1314-29. PMID 18952095 DOI: 10.1016/J.Jmb.2008.10.022 |
0.485 |
|
| 2008 |
Yin J, Garen CR, Cherney MM, Cherney LT, James MN. Expression, purification and preliminary crystallographic analysis of N-acetylglucosamine-1-phosphate uridylyltransferase from Mycobacterium tuberculosis. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 64: 805-8. PMID 18765909 DOI: 10.1107/S1744309108024500 |
0.354 |
|
| 2008 |
Cherney LT, Cherney MM, Garen CR, Lu GJ, James MN. Structure of the C-terminal domain of the arginine repressor protein from Mycobacterium tuberculosis. Acta Crystallographica. Section D, Biological Crystallography. 64: 950-6. PMID 18703843 DOI: 10.1107/S0907444908021513 |
0.452 |
|
| 2008 |
Cherney MM, Garen CR, James MN. Crystal structure of Mycobacterium tuberculosis Rv0760c at 1.50 A resolution, a structural homolog of Delta(5)-3-ketosteroid isomerase. Biochimica Et Biophysica Acta. 1784: 1625-32. PMID 18589008 DOI: 10.1016/J.Bbapap.2008.05.012 |
0.429 |
|
| 2008 |
Biswal BK, Morisseau C, Garen G, Cherney MM, Garen C, Niu C, Hammock BD, James MN. The molecular structure of epoxide hydrolase B from Mycobacterium tuberculosis and its complex with a urea-based inhibitor. Journal of Molecular Biology. 381: 897-912. PMID 18585390 DOI: 10.1016/J.Jmb.2008.06.030 |
0.501 |
|
| 2008 |
Witholt SJ, Sankaranarayanan R, Garen CR, Cherney MM, Cherney LT, James MN. Expression, purification, crystallization and preliminary X-ray analysis of Rv3117, a probable thiosulfate sulfurtransferase (CysA3) from Mycobacterium tuberculosis. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 64: 541-4. PMID 18540071 DOI: 10.1107/S1744309108014449 |
0.335 |
|
| 2008 |
Huitema C, Zhang J, Yin J, James MN, Vederas JC, Eltis LD. Heteroaromatic ester inhibitors of hepatitis A virus 3C proteinase: Evaluation of mode of action. Bioorganic & Medicinal Chemistry. 16: 5761-77. PMID 18407505 DOI: 10.1016/J.Bmc.2008.03.059 |
0.361 |
|
| 2008 |
Zhang J, Huitema C, Niu C, Yin J, James MN, Eltis LD, Vederas JC. Aryl methylene ketones and fluorinated methylene ketones as reversible inhibitors for severe acute respiratory syndrome (SARS) 3C-like proteinase. Bioorganic Chemistry. 36: 229-40. PMID 18295820 DOI: 10.1016/J.Bioorg.2008.01.001 |
0.345 |
|
| 2008 |
Lee TW, James MN. 1.2A-resolution crystal structures reveal the second tetrahedral intermediates of streptogrisin B (SGPB). Biochimica Et Biophysica Acta. 1784: 319-34. PMID 18157955 DOI: 10.1016/J.Bbapap.2007.11.012 |
0.418 |
|
| 2008 |
Sankaranarayanan R, Cherney MM, Cherney LT, Garen CR, Moradian F, James MN. The crystal structures of ornithine carbamoyltransferase from Mycobacterium tuberculosis and its ternary complex with carbamoyl phosphate and L-norvaline reveal the enzyme's catalytic mechanism. Journal of Molecular Biology. 375: 1052-63. PMID 18062991 DOI: 10.1016/J.Jmb.2007.11.025 |
0.504 |
|
| 2008 |
Mazumdar PA, Hulecki JC, Cherney MM, Garen CR, James MN. X-ray crystal structure of Mycobacterium tuberculosis haloalkane dehalogenase Rv2579. Biochimica Et Biophysica Acta. 1784: 351-62. PMID 18062934 DOI: 10.1016/J.Bbapap.2007.10.014 |
0.489 |
|
| 2008 |
Niu C, Yin J, Zhang J, Vederas JC, James MN. Molecular docking identifies the binding of 3-chloropyridine moieties specifically to the S1 pocket of SARS-CoV Mpro. Bioorganic & Medicinal Chemistry. 16: 293-302. PMID 17931870 DOI: 10.1016/J.Bmc.2007.09.034 |
0.411 |
|
| 2007 |
Lu GJ, Garen CR, Cherney MM, Cherney LT, Lee C, James MN. Expression, purification and preliminary X-ray analysis of the C-terminal domain of an arginine repressor protein from Mycobacterium tuberculosis. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 63: 936-9. PMID 18007044 DOI: 10.1107/S1744309107046374 |
0.41 |
|
| 2007 |
Murillo AC, Li HY, Alber T, Baker EN, Berger JM, Cherney LT, Cherney MM, Cho YS, Eisenberg D, Garen CR, Goulding CW, Hung LW, Ioerger TR, Jacobs WR, James MN, et al. High throughput crystallography of TB drug targets. Infectious Disorders Drug Targets. 7: 127-39. PMID 17970224 DOI: 10.2174/187152607781001853 |
0.392 |
|
| 2007 |
Pillai B, Cherney M, Diaper CM, Sutherland A, Blanchard JS, Vederas JC, James MN. Dynamics of catalysis revealed from the crystal structures of mutants of diaminopimelate epimerase. Biochemical and Biophysical Research Communications. 363: 547-53. PMID 17889830 DOI: 10.1016/J.Bbrc.2007.09.012 |
0.522 |
|
| 2007 |
Yin J, Niu C, Cherney MM, Zhang J, Huitema C, Eltis LD, Vederas JC, James MN. A mechanistic view of enzyme inhibition and peptide hydrolysis in the active site of the SARS-CoV 3C-like peptidase. Journal of Molecular Biology. 371: 1060-74. PMID 17599357 DOI: 10.1016/J.Jmb.2007.06.001 |
0.471 |
|
| 2007 |
Watanabe N, Cherney MM, van Belkum MJ, Marcus SL, Flegel MD, Clay MD, Deyholos MK, Vederas JC, James MN. Crystal structure of LL-diaminopimelate aminotransferase from Arabidopsis thaliana: a recently discovered enzyme in the biosynthesis of L-lysine by plants and Chlamydia. Journal of Molecular Biology. 371: 685-702. PMID 17583737 DOI: 10.1016/J.Jmb.2007.05.061 |
0.464 |
|
| 2007 |
Zhang J, Pettersson HI, Huitema C, Niu C, Yin J, James MN, Eltis LD, Vederas JC. Design, synthesis, and evaluation of inhibitors for severe acute respiratory syndrome 3C-like protease based on phthalhydrazide ketones or heteroaromatic esters. Journal of Medicinal Chemistry. 50: 1850-64. PMID 17381079 DOI: 10.1021/Jm061425K |
0.303 |
|
| 2007 |
Cherney LT, Cherney MM, Garen CR, Niu C, Moradian F, James MN. Crystal structure of N-acetyl-gamma-glutamyl-phosphate reductase from Mycobacterium tuberculosis in complex with NADP(+). Journal of Molecular Biology. 367: 1357-69. PMID 17316682 DOI: 10.1016/J.Jmb.2007.01.033 |
0.497 |
|
| 2007 |
Lee TW, Qasim MA, Laskowski M, James MN. Structural insights into the non-additivity effects in the sequence-to-reactivity algorithm for serine peptidases and their inhibitors. Journal of Molecular Biology. 367: 527-46. PMID 17266986 DOI: 10.1016/J.Jmb.2007.01.008 |
0.451 |
|
| 2007 |
Lemieux MJ, Fischer SJ, Cherney MM, Bateman KS, James MN. The crystal structure of the rhomboid peptidase from Haemophilus influenzae provides insight into intramembrane proteolysis. Proceedings of the National Academy of Sciences of the United States of America. 104: 750-4. PMID 17210913 DOI: 10.1073/Pnas.0609981104 |
0.445 |
|
| 2007 |
Lee TW, Cherney MM, Liu J, James KE, Powers JC, Eltis LD, James MN. Crystal structures reveal an induced-fit binding of a substrate-like Aza-peptide epoxide to SARS coronavirus main peptidase. Journal of Molecular Biology. 366: 916-32. PMID 17196984 DOI: 10.1016/J.Jmb.2006.11.078 |
0.427 |
|
| 2007 |
Pillai B, Cherney MM, Hiraga K, Takada K, Oda K, James MN. Crystal structure of scytalidoglutamic peptidase with its first potent inhibitor provides insights into substrate specificity and catalysis. Journal of Molecular Biology. 365: 343-61. PMID 17069854 DOI: 10.1016/J.Jmb.2006.09.058 |
0.527 |
|
| 2006 |
Garen CR, Cherney MM, Bergmann EM, James MN. The molecular structure of Rv1873, a conserved hypothetical protein from Mycobacterium tuberculosis, at 1.38 A resolution. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62: 1201-5. PMID 17142896 DOI: 10.1107/S1744309106046902 |
0.434 |
|
| 2006 |
Moradian F, Garen C, Cherney L, Cherney M, James MN. Expression, purification, crystallization and preliminary X-ray analysis of two arginine-biosynthetic enzymes from Mycobacterium tuberculosis. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62: 986-8. PMID 17012791 DOI: 10.1107/S1744309106034609 |
0.338 |
|
| 2006 |
James MN. The peptidases from fungi and viruses. Biological Chemistry. 387: 1023-9. PMID 16895471 DOI: 10.1515/Bc.2006.126 |
0.444 |
|
| 2006 |
Biswal BK, Au K, Cherney MM, Garen C, James MN. The molecular structure of Rv2074, a probable pyridoxine 5'-phosphate oxidase from Mycobacterium tuberculosis, at 1.6 angstroms resolution. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62: 735-42. PMID 16880544 DOI: 10.1107/S1744309106025012 |
0.508 |
|
| 2006 |
Yin J, Cherney MM, Bergmann EM, Zhang J, Huitema C, Pettersson H, Eltis LD, Vederas JC, James MN. An episulfide cation (thiiranium ring) trapped in the active site of HAV 3C proteinase inactivated by peptide-based ketone inhibitors. Journal of Molecular Biology. 361: 673-86. PMID 16860823 DOI: 10.1016/J.Jmb.2006.06.047 |
0.463 |
|
| 2006 |
Yin J, Xu LX, Cherney MM, Raux-Deery E, Bindley AA, Savchenko A, Walker JR, Cuff ME, Warren MJ, James MN. Crystal structure of the vitamin B12 biosynthetic cobaltochelatase, CbiXS, from Archaeoglobus fulgidus. Journal of Structural and Functional Genomics. 7: 37-50. PMID 16835730 DOI: 10.1007/S10969-006-9008-X |
0.437 |
|
| 2006 |
Biswal BK, Wang M, Cherney MM, Chan L, Yannopoulos CG, Bilimoria D, Bedard J, James MN. Non-nucleoside inhibitors binding to hepatitis C virus NS5B polymerase reveal a novel mechanism of inhibition. Journal of Molecular Biology. 361: 33-45. PMID 16828488 DOI: 10.1016/J.Jmb.2006.05.074 |
0.38 |
|
| 2006 |
Fraser ME, Cherney MM, Marcato P, Mulvey GL, Armstrong GD, James MN. Binding of adenine to Stx2, the protein toxin from Escherichia coli O157:H7. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62: 627-30. PMID 16820678 DOI: 10.1107/S1744309106021968 |
0.376 |
|
| 2006 |
Pillai B, Cherney MM, Diaper CM, Sutherland A, Blanchard JS, Vederas JC, James MN. Structural insights into stereochemical inversion by diaminopimelate epimerase: an antibacterial drug target. Proceedings of the National Academy of Sciences of the United States of America. 103: 8668-73. PMID 16723397 DOI: 10.1073/Pnas.0602537103 |
0.458 |
|
| 2006 |
Lemieux MJ, Mark BL, Cherney MM, Withers SG, Mahuran DJ, James MN. Crystallographic structure of human beta-hexosaminidase A: interpretation of Tay-Sachs mutations and loss of GM2 ganglioside hydrolysis. Journal of Molecular Biology. 359: 913-29. PMID 16698036 DOI: 10.1016/J.Jmb.2006.04.004 |
0.667 |
|
| 2006 |
Biswal BK, Garen G, Cherney MM, Garen C, James MN. Cloning, expression, purification, crystallization and preliminary X-ray studies of epoxide hydrolases A and B from Mycobacterium tuberculosis. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62: 136-8. PMID 16511284 DOI: 10.1107/S1744309106000637 |
0.341 |
|
| 2006 |
Maynes JT, Luu HA, Cherney MM, Andersen RJ, Williams D, Holmes CF, James MN. Crystal structures of protein phosphatase-1 bound to motuporin and dihydromicrocystin-LA: elucidation of the mechanism of enzyme inhibition by cyanobacterial toxins. Journal of Molecular Biology. 356: 111-20. PMID 16343532 DOI: 10.1016/J.Jmb.2005.11.019 |
0.728 |
|
| 2005 |
Lemieux MJ, Ference C, Cherney MM, Wang M, Garen C, James MN. The crystal structure of Rv0793, a hypothetical monooxygenase from M. tuberculosis. Journal of Structural and Functional Genomics. 6: 245-57. PMID 16496224 DOI: 10.1007/S10969-005-9004-6 |
0.324 |
|
| 2005 |
Diaper CM, Sutherland A, Pillai B, James MN, Semchuk P, Blanchard JS, Vederas JC. The stereoselective synthesis of aziridine analogues of diaminopimelic acid (DAP) and their interaction with dap epimerase. Organic & Biomolecular Chemistry. 3: 4402-11. PMID 16327902 DOI: 10.1039/B513409A |
0.353 |
|
| 2005 |
Yin J, Bergmann EM, Cherney MM, Lall MS, Jain RP, Vederas JC, James MN. Dual modes of modification of hepatitis A virus 3C protease by a serine-derived beta-lactone: selective crystallization and formation of a functional catalytic triad in the active site. Journal of Molecular Biology. 354: 854-71. PMID 16288920 DOI: 10.1016/J.Jmb.2005.09.074 |
0.485 |
|
| 2005 |
Biswal BK, Cherney MM, Wang M, Garen C, James MN. Structures of Mycobacterium tuberculosispyridoxine 5'-phosphate oxidase and its complexes with flavin mononucleotide and pyridoxal 5'-phosphate. Acta Crystallographica. Section D, Biological Crystallography. 61: 1492-9. PMID 16239726 DOI: 10.1107/S0907444905026673 |
0.527 |
|
| 2005 |
Lee TW, Cherney MM, Huitema C, Liu J, James KE, Powers JC, Eltis LD, James MN. Crystal structures of the main peptidase from the SARS coronavirus inhibited by a substrate-like aza-peptide epoxide. Journal of Molecular Biology. 353: 1137-51. PMID 16219322 DOI: 10.1016/J.Jmb.2005.09.004 |
0.433 |
|
| 2005 |
Kataoka Y, Takada K, Oyama H, Tsunemi M, James MN, Oda K. Catalytic residues and substrate specificity of scytalidoglutamic peptidase, the first member of the eqolisin in family (G1) of peptidases. Febs Letters. 579: 2991-4. PMID 15907842 DOI: 10.1016/J.Febslet.2005.04.050 |
0.42 |
|
| 2005 |
Maynes JT, Cherney MM, Qasim MA, Laskowski M, James MN. Structure of the subtilisin Carlsberg-OMTKY3 complex reveals two different ovomucoid conformations. Acta Crystallographica. Section D, Biological Crystallography. 61: 580-8. PMID 15858268 DOI: 10.1107/S0907444905004889 |
0.734 |
|
| 2005 |
Biswal BK, Cherney MM, Wang M, Chan L, Yannopoulos CG, Bilimoria D, Nicolas O, Bedard J, James MN. Crystal structures of the RNA-dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors. The Journal of Biological Chemistry. 280: 18202-10. PMID 15746101 DOI: 10.1074/Jbc.M413410200 |
0.467 |
|
| 2004 |
Jain RP, Pettersson HI, Zhang J, Aull KD, Fortin PD, Huitema C, Eltis LD, Parrish JC, James MN, Wishart DS, Vederas JC. Synthesis and evaluation of keto-glutamine analogues as potent inhibitors of severe acute respiratory syndrome 3CLpro. Journal of Medicinal Chemistry. 47: 6113-6. PMID 15566280 DOI: 10.1021/Jm0494873 |
0.357 |
|
| 2004 |
Maynes JT, Perreault KR, Cherney MM, Luu HA, James MN, Holmes CF. Crystal structure and mutagenesis of a protein phosphatase-1:calcineurin hybrid elucidate the role of the beta12-beta13 loop in inhibitor binding. The Journal of Biological Chemistry. 279: 43198-206. PMID 15280359 DOI: 10.1074/Jbc.M407184200 |
0.704 |
|
| 2004 |
Fraser ME, Fujinaga M, Cherney MM, Melton-Celsa AR, Twiddy EM, O'Brien AD, James MN. Structure of shiga toxin type 2 (Stx2) from Escherichia coli O157:H7. The Journal of Biological Chemistry. 279: 27511-7. PMID 15075327 DOI: 10.1074/Jbc.M401939200 |
0.39 |
|
| 2004 |
Fujinaga M, Cherney MM, Oyama H, Oda K, James MN. The molecular structure and catalytic mechanism of a novel carboxyl peptidase from Scytalidium lignicolum. Proceedings of the National Academy of Sciences of the United States of America. 101: 3364-9. PMID 14993599 DOI: 10.1073/Pnas.0400246101 |
0.476 |
|
| 2003 |
Maynes JT, Garen C, Cherney MM, Newton G, Arad D, Av-Gay Y, Fahey RC, James MN. The crystal structure of 1-D-myo-inosityl 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) from Mycobacterium tuberculosis reveals a zinc hydrolase with a lactate dehydrogenase fold. The Journal of Biological Chemistry. 278: 47166-70. PMID 12958317 DOI: 10.1074/Jbc.M308914200 |
0.73 |
|
| 2003 |
Barrette-Ng IH, Ng KK, Cherney MM, Pearce G, Ghani U, Ryan CA, James MN. Unbound form of tomato inhibitor-II reveals interdomain flexibility and conformational variability in the reactive site loops. The Journal of Biological Chemistry. 278: 31391-400. PMID 12788916 DOI: 10.1074/Jbc.M304562200 |
0.808 |
|
| 2003 |
Bernstein NK, Cherney MM, Yowell CA, Dame JB, James MN. Structural insights into the activation of P. vivax plasmepsin. Journal of Molecular Biology. 329: 505-24. PMID 12767832 DOI: 10.1016/S0022-2836(03)00444-3 |
0.788 |
|
| 2003 |
Barrette-Ng IH, Ng KK, Cherney MM, Pearce G, Ryan CA, James MN. Structural basis of inhibition revealed by a 1:2 complex of the two-headed tomato inhibitor-II and subtilisin Carlsberg. The Journal of Biological Chemistry. 278: 24062-71. PMID 12684499 DOI: 10.1074/Jbc.M302020200 |
0.802 |
|
| 2003 |
Mark BL, Mahuran DJ, Cherney MM, Zhao D, Knapp S, James MN. Crystal structure of human beta-hexosaminidase B: understanding the molecular basis of Sandhoff and Tay-Sachs disease. Journal of Molecular Biology. 327: 1093-109. PMID 12662933 DOI: 10.1016/S0022-2836(03)00216-X |
0.617 |
|
| 2003 |
Wang M, Ng KK, Cherney MM, Chan L, Yannopoulos CG, Bedard J, Morin N, Nguyen-Ba N, Alaoui-Ismaili MH, Bethell RC, James MN. Non-nucleoside analogue inhibitors bind to an allosteric site on HCV NS5B polymerase. Crystal structures and mechanism of inhibition. The Journal of Biological Chemistry. 278: 9489-95. PMID 12509436 DOI: 10.1074/Jbc.M209397200 |
0.449 |
|
| 2002 |
Toyota E, Ng KK, Kuninaga S, Sekizaki H, Itoh K, Tanizawa K, James MN. Crystal structure and nucleotide sequence of an anionic trypsin from chum salmon (Oncorhynchus keta) in comparison with Atlantic salmon (Salmo salar) and bovine trypsin. Journal of Molecular Biology. 324: 391-7. PMID 12445776 DOI: 10.1016/S0022-2836(02)01097-5 |
0.482 |
|
| 2002 |
Holmes CF, Maynes JT, Perreault KR, Dawson JF, James MN. Molecular enzymology underlying regulation of protein phosphatase-1 by natural toxins. Current Medicinal Chemistry. 9: 1981-9. PMID 12369866 DOI: 10.2174/0929867023368827 |
0.437 |
|
| 2002 |
Williams SJ, Mark BL, Vocadlo DJ, James MN, Withers SG. Aspartate 313 in the Streptomyces plicatus hexosaminidase plays a critical role in substrate-assisted catalysis by orienting the 2-acetamido group and stabilizing the transition state. The Journal of Biological Chemistry. 277: 40055-65. PMID 12171933 DOI: 10.1074/Jbc.M206481200 |
0.623 |
|
| 2002 |
Barrette-Ng IH, Ng KK, Mark BL, Van Aken D, Cherney MM, Garen C, Kolodenko Y, Gorbalenya AE, Snijder EJ, James MN. Structure of arterivirus nsp4. The smallest chymotrypsin-like proteinase with an alpha/beta C-terminal extension and alternate conformations of the oxyanion hole. The Journal of Biological Chemistry. 277: 39960-6. PMID 12163505 DOI: 10.1074/Jbc.M206978200 |
0.794 |
|
| 2002 |
Ramtohul YK, James MN, Vederas JC. Synthesis and evaluation of keto-glutamine analogues as inhibitors of hepatitis A virus 3C proteinase. The Journal of Organic Chemistry. 67: 3169-78. PMID 12003522 DOI: 10.1021/Jo0157831 |
0.396 |
|
| 2002 |
Lall MS, Ramtohul YK, James MN, Vederas JC. Serine and threonine beta-lactones: a new class of hepatitis A virus 3C cysteine proteinase inhibitors. The Journal of Organic Chemistry. 67: 1536-47. PMID 11871884 DOI: 10.1021/Jo0109016 |
0.362 |
|
| 2002 |
Ng KK, Cherney MM, Vazquez AL, Machin A, Alonso JM, Parra F, James MN. Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase. The Journal of Biological Chemistry. 277: 1381-7. PMID 11677245 DOI: 10.1074/Jbc.M109261200 |
0.398 |
|
| 2002 |
Mark BL, James MN. Anchimeric assistance in hexosaminidases Canadian Journal of Chemistry. 80: 1064-1074. DOI: 10.1139/V02-130 |
0.64 |
|
| 2001 |
Ghani U, Ng KK, Atta-ur-Rahman, Choudhary MI, Ullah N, James MN. Crystal structure of gamma-chymotrypsin in complex with 7-hydroxycoumarin. Journal of Molecular Biology. 314: 519-25. PMID 11846564 DOI: 10.1006/Jmbi.2001.5148 |
0.468 |
|
| 2001 |
Maynes JT, Bateman KS, Cherney MM, Das AK, Luu HA, Holmes CF, James MN. Crystal structure of the tumor-promoter okadaic acid bound to protein phosphatase-1. The Journal of Biological Chemistry. 276: 44078-82. PMID 11535607 DOI: 10.1074/Jbc.M107656200 |
0.469 |
|
| 2001 |
Mark BL, Vocadlo DJ, Zhao D, Knapp S, Withers SG, James MN. Biochemical and structural assessment of the 1-N-azasugar GalNAc-isofagomine as a potent family 20 beta-N-acetylhexosaminidase inhibitor. The Journal of Biological Chemistry. 276: 42131-7. PMID 11522797 DOI: 10.1074/Jbc.M107154200 |
0.624 |
|
| 2001 |
Mark BL, Parrish JC, Wang ZX, Wiebe LI, Knaus EE, James MN. (E)-1-(2'-deoxy-beta-D-ribofuranosyl)-2,4-difluoro-5-(2-iodovinyl)benzene. Acta Crystallographica. Section C, Crystal Structure Communications. 57: 758-60. PMID 11408697 DOI: 10.1107/S0108270101005029 |
0.549 |
|
| 2001 |
Lu SM, Lu W, Qasim MA, Anderson S, Apostol I, Ardelt W, Bigler T, Chiang YW, Cook J, James MN, Kato I, Kelly C, Kohr W, Komiyama T, Lin TY, et al. Predicting the reactivity of proteins from their sequence alone: Kazal family of protein inhibitors of serine proteinases. Proceedings of the National Academy of Sciences of the United States of America. 98: 1410-5. PMID 11171964 DOI: 10.1073/Pnas.98.4.1410 |
0.319 |
|
| 2001 |
Bateman KS, Huang K, Anderson S, Lu W, Qasim MA, Laskowski M, James MN. Contribution of peptide bonds to inhibitor-protease binding: crystal structures of the turkey ovomucoid third domain backbone variants OMTKY3-Pro18I and OMTKY3-psi[COO]-Leu18I in complex with Streptomyces griseus proteinase B (SGPB) and the structure of the free inhibitor, OMTKY-3-psi[CH2NH2+]-Asp19I. Journal of Molecular Biology. 305: 839-49. PMID 11162096 DOI: 10.1006/Jmbi.2000.4343 |
0.439 |
|
| 2001 |
Toyota E, Ng KK, Sekizaki H, Itoh K, Tanizawa K, James MN. X-ray crystallographic analyses of complexes between bovine beta-trypsin and Schiff base copper(II) or iron(III) chelates. Journal of Molecular Biology. 305: 471-9. PMID 11152605 DOI: 10.1006/Jmbi.2000.4303 |
0.362 |
|
| 2001 |
Mark BL, Vocadlo DJ, Knapp S, Triggs-Raine BL, Withers SG, James MN. Crystallographic evidence for substrate-assisted catalysis in a bacterial beta-hexosaminidase. The Journal of Biological Chemistry. 276: 10330-7. PMID 11124970 DOI: 10.1074/Jbc.M011067200 |
0.611 |
|
| 2000 |
Rochet JC, Brownie ER, Oikawa K, Hicks LD, Fraser ME, James MN, Kay CM, Bridger WA, Wolodko WT. Pig heart CoA transferase exists as two oligomeric forms separated by a large kinetic barrier. Biochemistry. 39: 11291-302. PMID 10985774 DOI: 10.1021/Bi0003184 |
0.381 |
|
| 2000 |
Ng KK, Petersen JF, Cherney MM, Garen C, Zalatoris JJ, Rao-Naik C, Dunn BM, Martzen MR, Peanasky RJ, James MN. Structural basis for the inhibition of porcine pepsin by Ascaris pepsin inhibitor-3. Nature Structural Biology. 7: 653-7. PMID 10932249 DOI: 10.1038/77950 |
0.499 |
|
| 2000 |
Fraser ME, James MN, Bridger WA, Wolodko WT. Phosphorylated and dephosphorylated structures of pig heart, GTP-specific succinyl-CoA synthetase. Journal of Molecular Biology. 299: 1325-39. PMID 10873456 DOI: 10.1006/Jmbi.2000.3807 |
0.469 |
|
| 2000 |
Bateman KS, Anderson S, Lu W, Qasim MA, Laskowski M, James MN. Deleterious effects of beta-branched residues in the S1 specificity pocket of Streptomyces griseus proteinase B (SGPB): crystal structures of the turkey ovomucoid third domain variants Ile18I, Val18I, Thr18I, and Ser18I in complex with SGPB. Protein Science : a Publication of the Protein Society. 9: 83-94. PMID 10739250 DOI: 10.1110/Ps.9.1.83 |
0.474 |
|
| 2000 |
Fujinaga M, Cherney MM, Tarasova NI, Bartlett PA, Hanson JE, James MN. Structural study of the complex between human pepsin and a phosphorus-containing peptidic -transition-state analog. Acta Crystallographica. Section D, Biological Crystallography. 56: 272-9. PMID 10713513 DOI: 10.1107/S0907444999016376 |
0.41 |
|
| 1999 |
Bernstein NK, James MN. Novel ways to prevent proteolysis - prophytepsin and proplasmepsin II. Current Opinion in Structural Biology. 9: 684-9. PMID 10607668 DOI: 10.1016/S0959-440X(99)00030-5 |
0.744 |
|
| 1999 |
Bergmann EM, Cherney MM, Mckendrick J, Frormann S, Luo C, Malcolm BA, Vederas JC, James MN. Crystal structure of an inhibitor complex of the 3C proteinase from hepatitis A virus (HAV) and implications for the polyprotein processing in HAV. Virology. 265: 153-63. PMID 10603326 DOI: 10.1006/Viro.1999.9968 |
0.456 |
|
| 1999 |
Petersen JF, Cherney MM, Liebig HD, Skern T, Kuechler E, James MN. The structure of the 2A proteinase from a common cold virus: a proteinase responsible for the shut-off of host-cell protein synthesis. The Embo Journal. 18: 5463-75. PMID 10523291 DOI: 10.1093/Emboj/18.20.5463 |
0.413 |
|
| 1999 |
Seipelt J, Guarné A, Bergmann E, James M, Sommergruber W, Fita I, Skern T. The structures of picornaviral proteinases. Virus Research. 62: 159-68. PMID 10507325 DOI: 10.1016/S0168-1702(99)00043-X |
0.32 |
|
| 1999 |
Khan AR, Khazanovich-Bernstein N, Bergmann EM, James MN. Structural aspects of activation pathways of aspartic protease zymogens and viral 3C protease precursors. Proceedings of the National Academy of Sciences of the United States of America. 96: 10968-75. PMID 10500110 DOI: 10.1073/Pnas.96.20.10968 |
0.487 |
|
| 1999 |
Caputo A, Parrish JC, James MN, Powers JC, Bleackley RC. Electrostatic reversal of serine proteinase substrate specificity. Proteins. 35: 415-24. PMID 10382669 DOI: 10.1002/(Sici)1097-0134(19990601)35:4<415::Aid-Prot5>3.0.Co;2-7 |
0.4 |
|
| 1999 |
Qasim MA, Lu SM, Ding J, Bateman KS, James MN, Anderson S, Song J, Markley JL, Ganz PJ, Saunders CW, Laskowski M. Thermodynamic criterion for the conformation of P1 residues of substrates and of inhibitors in complexes with serine proteinases. Biochemistry. 38: 7142-50. PMID 10353824 DOI: 10.1021/Bi990265U |
0.441 |
|
| 1999 |
Bernstein NK, Cherney MM, Loetscher H, Ridley RG, James MN. Crystal structure of the novel aspartic proteinase zymogen proplasmepsin II from plasmodium falciparum. Nature Structural Biology. 6: 32-7. PMID 9886289 DOI: 10.1038/4905 |
0.78 |
|
| 1999 |
Fujinaga M, Huang K, Bateman KS, James MN. Computational analysis of the binding of P1 variants of domain 3 of turkey ovomucoid inhibitor to Streptomyces griseus protease B. Journal of Molecular Biology. 284: 1683-94. PMID 9878379 DOI: 10.1006/Jmbi.1998.2277 |
0.34 |
|
| 1998 |
Khan AR, Parrish JC, Fraser ME, Smith WW, Bartlett PA, James MN. Lowering the entropic barrier for binding conformationally flexible inhibitors to enzymes. Biochemistry. 37: 16839-45. PMID 9836576 DOI: 10.1021/Bi9821364 |
0.447 |
|
| 1998 |
Mark BL, Wasney GA, Salo TJ, Khan AR, Cao Z, Robbins PW, James MN, Triggs-Raine BL. Structural and functional characterization of Streptomyces plicatus beta-N-acetylhexosaminidase by comparative molecular modeling and site-directed mutagenesis. The Journal of Biological Chemistry. 273: 19618-24. PMID 9677388 DOI: 10.1074/Jbc.273.31.19618 |
0.638 |
|
| 1998 |
Petersen JF, Chernaia MM, Rao-Naik C, Zalatoris JL, Dunn BM, James MN. X-ray crystallographic studies of the complex between porcine pepsin and the aspartic proteinase inhibitor PI-3 from the nematode Ascaris suum. Advances in Experimental Medicine and Biology. 436: 391-5. PMID 9561247 DOI: 10.1007/978-1-4615-5373-1_55 |
0.417 |
|
| 1998 |
Fraser ME, Meyer JH, Bartlett PA, James MN. Overcoming the unfavourable entropic contribution of ligand binding with a macrocyclic inhibitor bound to penicillopepsin. Advances in Experimental Medicine and Biology. 436: 355-9. PMID 9561242 DOI: 10.1007/978-1-4615-5373-1_50 |
0.303 |
|
| 1998 |
Khan AR, Chernaia MM, Tarasova NI, James MN. Crystallographic studies of an activation intermediate of human gastricsin. Advances in Experimental Medicine and Biology. 436: 265-70. PMID 9561229 DOI: 10.1007/978-1-4615-5373-1_37 |
0.448 |
|
| 1998 |
Bateman KS, Chernaia MM, Tarasova NI, James MN. Crystal structure of human pepsinogen A. Advances in Experimental Medicine and Biology. 436: 259-63. PMID 9561228 DOI: 10.1107/S0108767396094937 |
0.337 |
|
| 1997 |
Khan AR, Cherney MM, Tarasova NI, James MN. Structural characterization of activation 'intermediate 2' on the pathway to human gastricsin. Nature Structural Biology. 4: 1010-5. PMID 9406551 DOI: 10.1038/Nsb1297-1010 |
0.426 |
|
| 1997 |
Mosimann SC, Cherney MM, Sia S, Plotch S, James MN. Refined X-ray crystallographic structure of the poliovirus 3C gene product. Journal of Molecular Biology. 273: 1032-47. PMID 9367789 DOI: 10.1006/Jmbi.1997.1306 |
0.484 |
|
| 1997 |
Strynadka NC, Cherney M, Sielecki AR, Li MX, Smillie LB, James MN. Structural details of a calcium-induced molecular switch: X-ray crystallographic analysis of the calcium-saturated N-terminal domain of troponin C at 1.75 A resolution. Journal of Molecular Biology. 273: 238-55. PMID 9367759 DOI: 10.1006/Jmbi.1997.1257 |
0.559 |
|
| 1997 |
Qasim MA, Ganz PJ, Saunders CW, Bateman KS, James MN, Laskowski M. Interscaffolding additivity. Association of P1 variants of eglin c and of turkey ovomucoid third domain with serine proteinases. Biochemistry. 36: 1598-607. PMID 9048543 DOI: 10.1021/Bi9620870 |
0.407 |
|
| 1997 |
Khan AR, Johnson KA, Braam J, James MN. Comparative modeling of the three-dimensional structure of the calmodulin-related TCH2 protein from Arabidopsis. Proteins. 27: 144-53. PMID 9037719 DOI: 10.1002/(Sici)1097-0134(199701)27:1<144::Aid-Prot14>3.0.Co;2-N |
0.418 |
|
| 1997 |
Bergmann EM, Mosimann SC, Chernaia MM, Malcolm BA, James MN. The refined crystal structure of the 3C gene product from hepatitis A virus: specific proteinase activity and RNA recognition. Journal of Virology. 71: 2436-48. PMID 9032381 DOI: 10.1128/JVI.71.3.2436-2448.1997 |
0.378 |
|
| 1997 |
Khazanovich N, Bateman K, Chernaia M, Michalak M, James M. Crystal structure of the yeast cell-cycle control protein, p13suc1, in a strand-exchanged dimer. Structure (London, England : 1993). 4: 299-309. PMID 8805536 DOI: 10.1016/S0969-2126(96)00034-2 |
0.359 |
|
| 1996 |
Strynadka NC, James MN. Lysozyme: a model enzyme in protein crystallography. Exs. 75: 185-222. PMID 8765301 |
0.658 |
|
| 1996 |
Mosimann SC, Newton DL, Youle RJ, James MN. X-ray crystallographic structure of recombinant eosinophil-derived neurotoxin at 1.83 A resolution. Journal of Molecular Biology. 260: 540-52. PMID 8759319 DOI: 10.1006/Jmbi.1996.0420 |
0.44 |
|
| 1996 |
Fujinaga M, Chernaia MM, Halenbeck R, Koths K, James MN. The crystal structure of PR3, a neutrophil serine proteinase antigen of Wegener's granulomatosis antibodies. Journal of Molecular Biology. 261: 267-78. PMID 8757293 DOI: 10.1006/Jmbi.1996.0458 |
0.503 |
|
| 1996 |
Mosimann S, Meleshko R, James MN. A critical assessment of comparative molecular modeling of tertiary structures of proteins. Proteins. 23: 301-17. PMID 8710824 DOI: 10.1002/Prot.340230305 |
0.352 |
|
| 1996 |
Strynadka NC, Jensen SE, Alzari PM, James MN. A potent new mode of beta-lactamase inhibition revealed by the 1.7 A X-ray crystallographic structure of the TEM-1-BLIP complex. Nature Structural Biology. 3: 290-7. PMID 8605632 DOI: 10.1038/Nsb0396-290 |
0.626 |
|
| 1996 |
Strynadka NC, Eisenstein M, Katchalski-Katzir E, Shoichet BK, Kuntz ID, Abagyan R, Totrov M, Janin J, Cherfils J, Zimmerman F, Olson A, Duncan B, Rao M, Jackson R, Sternberg M, ... James MN, et al. Molecular docking programs successfully predict the binding of a beta-lactamase inhibitory protein to TEM-1 beta-lactamase. Nature Structural Biology. 3: 233-9. PMID 8605624 DOI: 10.1038/Nsb0396-233 |
0.615 |
|
| 1995 |
Tarasova N, James M, Moore S, Sielecki A, Chernaia M. The Molecular Structure of Human Progastricsin and its Comparison with that of Porcine Pepsinogen Advances in Experimental Medicine and Biology. 362: 11-18. PMID 8540308 DOI: 10.1007/978-1-4615-1871-6_2 |
0.387 |
|
| 1995 |
Paetzel M, Chernaia M, Strynadka N, Tschantz W, Cao G, Dalbey RE, James MN. Crystallization of a soluble, catalytically active form of Escherichia coli leader peptidase. Proteins. 23: 122-5. PMID 8539246 DOI: 10.1002/Prot.340230115 |
0.603 |
|
| 1995 |
Moore SA, James MN. Structural refinement of the non-fluorescent flavoprotein from Photobacterium leiognathi at 1.60 A resolution. Journal of Molecular Biology. 249: 195-214. PMID 7776372 DOI: 10.1006/Jmbi.1995.0289 |
0.457 |
|
| 1995 |
Moore SA, Sielecki AR, Chernaia MM, Tarasova NI, James MN. Crystal and molecular structures of human progastricsin at 1.62 A resolution. Journal of Molecular Biology. 247: 466-85. PMID 7714902 DOI: 10.1006/Jmbi.1994.0154 |
0.497 |
|
| 1995 |
Fraser ME, Chernaia MM, Kozlov YV, James MN. Crystal structure of the holotoxin from Shigella dysenteriae at 2.5 A resolution. Nature Structural Biology. 1: 59-64. PMID 7656009 DOI: 10.1038/Nsb0194-59 |
0.453 |
|
| 1994 |
McPhalen CA, Sielecki AR, Santarsiero BD, James MN. Refined crystal structure of rat parvalbumin, a mammalian alpha-lineage parvalbumin, at 2.0 A resolution. Journal of Molecular Biology. 235: 718-32. PMID 8289291 DOI: 10.1006/Jmbi.1994.1023 |
0.626 |
|
| 1994 |
Allaire M, Chernaia MM, Malcolm BA, James MN. Picornaviral 3C cysteine proteinases have a fold similar to chymotrypsin-like serine proteinases. Nature. 369: 72-6. PMID 8164744 DOI: 10.1038/369072A0 |
0.391 |
|
| 1994 |
Strynadka NC, Jensen SE, Johns K, Blanchard H, Page M, Matagne A, Frère JM, James MN. Structural and kinetic characterization of a beta-lactamase-inhibitor protein. Nature. 368: 657-60. PMID 8145854 DOI: 10.1038/368657A0 |
0.614 |
|
| 1994 |
Mosimann SC, Ardelt W, James MN. Refined 1.7 A X-ray crystallographic structure of P-30 protein, an amphibian ribonuclease with anti-tumor activity. Journal of Molecular Biology. 236: 1141-53. PMID 8120892 DOI: 10.1016/0022-2836(94)90017-5 |
0.474 |
|
| 1994 |
Blanchard H, James MN. A crystallographic re-investigation into the structure of Streptomyces griseus proteinase A reveals an acyl-enzyme intermediate. Journal of Molecular Biology. 241: 574-87. PMID 8057380 DOI: 10.1006/Jmbi.1994.1532 |
0.403 |
|
| 1994 |
Huang K, Strynadka NC, Bernard VD, Peanasky RJ, James MN. The molecular structure of the complex of Ascaris chymotrypsin/elastase inhibitor with porcine elastase. Structure (London, England : 1993). 2: 679-89. PMID 7922044 |
0.599 |
|
| 1994 |
Moore SA, James MN. Common structural features of the luxF protein and the subunits of bacterial luciferase: evidence for a (beta alpha)8 fold in luciferase. Protein Science : a Publication of the Protein Society. 3: 1914-26. PMID 7703838 DOI: 10.1002/Pro.5560031103 |
0.407 |
|
| 1994 |
Caputo A, James MN, Powers JC, Hudig D, Bleackley RC. Conversion of the substrate specificity of mouse proteinase granzyme B. Nature Structural Biology. 1: 364-7. PMID 7664048 DOI: 10.1038/Nsb0694-364 |
0.384 |
|
| 1993 |
Chernaia MM, Malcolm BA, Allaire M, James MN. Hepatitis A virus 3C proteinase: some properties, crystallization and preliminary crystallographic characterization. Journal of Molecular Biology. 234: 890-3. PMID 8254682 DOI: 10.1006/Jmbi.1993.1636 |
0.38 |
|
| 1993 |
Moore S, James M, O'Kane D, Lee J. Crystal structure of a flavoprotein related to the subunits of bacterial luciferase. The Embo Journal. 12: 1767-1774. DOI: 10.1002/J.1460-2075.1993.Tb05824.X |
0.446 |
|
| 1992 |
Andreeva NS, James MN. Why does pepsin have a negative charge at very low pH? An analysis of conserved charged residues in aspartic proteinases. Advances in Experimental Medicine and Biology. 306: 39-45. PMID 1812734 DOI: 10.1007/978-1-4684-6012-4_4 |
0.336 |
|
| 1992 |
Bank RA, Russell RB, Pals G, James MN. Consequences of intramolecular ionic interactions for the activation rate of human pepsinogens A and C as revealed by molecular modelling. Advances in Experimental Medicine and Biology. 306: 101-5. PMID 1812695 DOI: 10.1007/978-1-4684-6012-4_11 |
0.325 |
|
| 1992 |
Huang K, Kodandapani R, Kallwass H, Hogan JK, Parris W, Friesen JD, Gold M, Jones JB, James MN. Crystallization and preliminary X-ray diffraction studies of two mutants of lactate dehydrogenase from Bacillus stearothermophilus. Proteins. 13: 158-61. PMID 1620698 DOI: 10.1002/Prot.340130209 |
0.391 |
|
| 1992 |
Fraser ME, Strynadka NC, Bartlett PA, Hanson JE, James MN. Crystallographic analysis of transition-state mimics bound to penicillopepsin: phosphorus-containing peptide analogues. Biochemistry. 31: 5201-14. PMID 1606144 DOI: 10.2210/Pdb1Ppm/Pdb |
0.58 |
|
| 1992 |
Moore SA, James MN, O'Kane DJ, Lee J. Crystallization of Photobacterium leiognathi non-fluorescent flavoprotein, an unusual flavoprotein with limited sequence identity to bacterial luciferase. Journal of Molecular Biology. 224: 523-6. PMID 1560468 DOI: 10.1016/0022-2836(92)91015-H |
0.313 |
|
| 1992 |
Mosimann SC, Johns KL, Ardelt W, Mikulski SM, Shogen K, James MN. Comparative molecular modeling and crystallization of P-30 protein: a novel antitumor protein of Rana pipiens oocytes and early embryos. Proteins. 14: 392-400. PMID 1438177 DOI: 10.1002/Prot.340140308 |
0.399 |
|
| 1992 |
Strynadka NC, Adachi H, Jensen SE, Johns K, Sielecki A, Betzel C, Sutoh K, James MN. Molecular structure of the acyl-enzyme intermediate in beta-lactam hydrolysis at 1.7 A resolution. Nature. 359: 700-5. PMID 1436034 DOI: 10.1038/359700A0 |
0.636 |
|
| 1991 |
Brito RM, Putkey JA, Strynadka NC, James MN, Rosevear PR. Comparative NMR studies on cardiac troponin C and a mutant incapable of binding calcium at site II. Biochemistry. 30: 10236-45. PMID 1931952 DOI: 10.1021/Bi00106A023 |
0.625 |
|
| 1991 |
Strynadka NC, James MN. Lysozyme revisited: crystallographic evidence for distortion of an N-acetylmuramic acid residue bound in site D. Journal of Molecular Biology. 220: 401-24. PMID 1856865 DOI: 10.1016/0022-2836(91)90021-W |
0.622 |
|
| 1991 |
McPhalen CA, Strynadka NC, James MN. Calcium-binding sites in proteins: a structural perspective. Advances in Protein Chemistry. 42: 77-144. PMID 1793008 DOI: 10.1016/S0065-3233(08)60535-5 |
0.545 |
|
| 1990 |
Strynadka NC, James MN. Model for the interaction of amphiphilic helices with troponin C and calmodulin. Proteins. 7: 234-48. PMID 2362945 DOI: 10.1002/Prot.340070305 |
0.601 |
|
| 1990 |
Sielecki AR, Fedorov AA, Boodhoo A, Andreeva NS, James MN. Molecular and crystal structures of monoclinic porcine pepsin refined at 1.8 A resolution. Journal of Molecular Biology. 214: 143-70. PMID 2115087 DOI: 10.1016/0022-2836(90)90153-D |
0.495 |
|
| 1989 |
Strynadka NC, James MN. Crystal structures of the helix-loop-helix calcium-binding proteins. Annual Review of Biochemistry. 58: 951-98. PMID 2673026 DOI: 10.1146/annurev.bi.58.070189.004511 |
0.545 |
|
| 1989 |
Greenblatt HM, Ryan CA, James MN. Structure of the complex of Streptomyces griseus proteinase B and polypeptide chymotrypsin inhibitor-1 from Russet Burbank potato tubers at 2.1 A resolution. Journal of Molecular Biology. 205: 201-28. PMID 2494344 DOI: 10.1016/0022-2836(89)90376-8 |
0.502 |
|
| 1989 |
Sielecki AR, Hayakawa K, Fujinaga M, Murphy ME, Fraser M, Muir AK, Carilli CT, Lewicki JA, Baxter JD, James MN. Structure of recombinant human renin, a target for cardiovascular-active drugs, at 2.5 A resolution. Science (New York, N.Y.). 243: 1346-51. PMID 2493678 DOI: 10.1126/Science.2493678 |
0.421 |
|
| 1988 |
Strynadka NC, James MN. Two trifluoperazine-binding sites on calmodulin predicted from comparative molecular modeling with troponin-C. Proteins. 3: 1-17. PMID 3375233 DOI: 10.1002/Prot.340030102 |
0.639 |
|
| 1987 |
McPhalen CA, James MN. Crystal and molecular structure of the serine proteinase inhibitor CI-2 from barley seeds. Biochemistry. 26: 261-9. PMID 3828302 DOI: 10.1021/BI00375A036 |
0.32 |
|
| 1987 |
Fujinaga M, James MN. Rat submaxillary gland serine protease, tonin. Structure solution and refinement at 1.8 A resolution. Journal of Molecular Biology. 195: 373-96. PMID 2821276 DOI: 10.1016/0022-2836(87)90658-9 |
0.485 |
|
| 1986 |
Moult J, James MN. An algorithm for determining the conformation of polypeptide segments in proteins by systematic search Proteins. 1: 146-163. PMID 3130622 DOI: 10.1002/Prot.340010207 |
0.372 |
|
| 1985 |
McPhalen CA, Schnebli HP, James MN. Crystal and molecular structure of the inhibitor eglin from leeches in complex with subtilisin Carlsberg. Febs Letters. 188: 55-8. PMID 3926539 DOI: 10.1016/0014-5793(85)80873-5 |
0.442 |
|
| 1985 |
Fujinaga M, Delbaere LT, Brayer GD, James MN. Refined structure of alpha-lytic protease at 1.7 A resolution. Analysis of hydrogen bonding and solvent structure. Journal of Molecular Biology. 184: 479-502. PMID 3900416 DOI: 10.1016/0022-2836(85)90296-7 |
0.678 |
|
| 1985 |
James MN, Sielecki AR. Stereochemical analysis of peptide bond hydrolysis catalyzed by the aspartic proteinase penicillopepsin. Biochemistry. 24: 3701-13. PMID 3899173 DOI: 10.1021/Bi00335A045 |
0.425 |
|
| 1984 |
Hofmann T, Hodges RS, James MN. Effect of pH on the activities of penicillopepsin and Rhizopus pepsin and a proposal for the productive substrate binding mode in penicillopepsin. Biochemistry. 23: 635-43. PMID 6424704 DOI: 10.1021/Bi00299A008 |
0.372 |
|
| 1984 |
Osterlund BR, Hayakawa K, Madsen NB, James MN. Crystallization of glycogen debranching enzyme. Journal of Molecular Biology. 174: 557-9. PMID 6232392 DOI: 10.1016/0022-2836(84)90336-X |
0.351 |
|
| 1984 |
Read R, Fujinaga M, Sielecki A, Ardelt W, Laskowski Jr M, James M. Conformational flexibility in the third domain of the turkey ovomucoid inhibitor bound to SGPB and α-chymotrypsin Acta Crystallographica Section a Foundations of Crystallography. 40: C50-C51. DOI: 10.1107/S0108767384098226 |
0.343 |
|
| 1983 |
McPhalen CA, Evans C, Hayakawa K, Jonassen I, Svendsen I, James MN. Preliminary crystallographic data for the serine protease inhibitor CI-2 from barley seeds. Journal of Molecular Biology. 168: 445-7. PMID 6604167 DOI: 10.1016/S0022-2836(83)80028-X |
0.343 |
|
| 1983 |
James MN, Sielecki AR. Structure and refinement of penicillopepsin at 1.8 A resolution. Journal of Molecular Biology. 163: 299-361. PMID 6341600 DOI: 10.1016/0022-2836(83)90008-6 |
0.431 |
|
| 1982 |
James MN, Sielecki A, Salituro F, Rich DH, Hofmann T. Conformational flexibility in the active sites of aspartyl proteinases revealed by a pepstatin fragment binding to penicillopepsin. Proceedings of the National Academy of Sciences of the United States of America. 79: 6137-41. PMID 6755464 DOI: 10.1073/Pnas.79.20.6137 |
0.485 |
|
| 1982 |
Fujinaga M, Read RJ, Sielecki A, Ardelt W, Laskowski M, James MN. Refined crystal structure of the molecular complex of Streptomyces griseus protease B, a serine protease, with the third domain of the ovomucoid inhibitor from turkey Proceedings of the National Academy of Sciences of the United States of America. 79: 4868-4872. PMID 6750612 DOI: 10.1073/Pnas.79.16.4868 |
0.448 |
|
| 1981 |
Bauer CA, Brayer GD, Sielecki AR, James MN. Active site of alpha-lytic protease: enzyme-substrate interactions. European Journal of Biochemistry / Febs. 120: 289-94. PMID 7032913 DOI: 10.1111/J.1432-1033.1981.Tb05702.X |
0.412 |
|
| 1980 |
James MN, Sielecki AR, Brayer GD, Delbaere LT, Bauer CA. Structures of product and inhibitor complexes of Streptomyces griseus protease A at 1.8 A resolution. A model for serine protease catalysis. Journal of Molecular Biology. 144: 43-88. PMID 6783761 DOI: 10.1016/0022-2836(80)90214-4 |
0.693 |
|
| 1980 |
James MN, Brayer GD, Delbaere LT, Sielecki AR, Gertler A. Crystal structure studies and inhibition kinetics of tripeptide chloromethyl ketone inhibitors with Streptomyces griseus protease B. Journal of Molecular Biology. 139: 423-38. PMID 6777499 DOI: 10.1016/0022-2836(80)90139-4 |
0.677 |
|
| 1979 |
Kelly JA, Sielecki AR, Sykes BD, James MN, Phillips DC. X-ray crystallography of the binding of the bacterial cell wall trisaccharide NAM-NAG-NAM to lysozyme. Nature. 282: 875-8. PMID 514367 DOI: 10.1038/282875A0 |
0.43 |
|
| 1979 |
Delbaere LT, Brayer GD, James MN. Comparison of the predicted model of alpha-lytic protease with the x-ray structure. Nature. 279: 165-8. PMID 440424 DOI: 10.1038/279165A0 |
0.678 |
|
| 1979 |
Sielecki AR, Hendrickson WA, Broughton CG, Delbaere LT, Brayer GD, James MN. Protein structure refinement: Streptomyces griseus serine protease A at 1.8 A resolution. Journal of Molecular Biology. 134: 781-804. PMID 119870 DOI: 10.1016/0022-2836(79)90486-8 |
0.657 |
|
| 1979 |
Brayer GD, Delbaere LT, James MN. Molecular structure of the alpha-lytic protease from Myxobacter 495 at 2.8 Angstroms resolution. Journal of Molecular Biology. 131: 743-75. PMID 117110 DOI: 10.1016/0022-2836(79)90200-6 |
0.701 |
|
| 1979 |
Delbaere LT, Brayer GD, James MN. The 2.8 A resolution structure of Streptomyces griseus protease B and its homology with alpha-chymotrypsin and Streptomyces griseus protease A. Canadian Journal of Biochemistry. 57: 135-44. PMID 110426 DOI: 10.1139/O79-017 |
0.69 |
|
| 1979 |
Brayer GD, Delbaere LT, James MN, Bauer CA, Thompson RC. Crystallographic and kinetic investigations of the covalent complex formed by a specific tetrapeptide aldehyde and the serine protease from Streptomyces griseus. Proceedings of the National Academy of Sciences of the United States of America. 76: 96-100. PMID 106392 DOI: 10.1073/Pnas.76.1.96 |
0.661 |
|
| 1978 |
Brayer GD, Delbaere LT, James MN. Molecular structure of crystalline Streptomyces griseus protease A at 2.8 A resolution. II. Molecular conformation, comparison with alpha-chymotrypsin and active-site geometry. Journal of Molecular Biology. 124: 261-83. PMID 101674 DOI: 10.1016/0022-2836(78)90159-6 |
0.703 |
|
| 1978 |
Brayer GD, Delbaere LT, James MN. Molecular structure of crystalline Streptomyces griseus protease A at 2.8 A resolution. I. Crystallization, data collection and structural analysis. Journal of Molecular Biology. 124: 243-59. PMID 101673 DOI: 10.1016/0022-2836(78)90158-4 |
0.656 |
|
| 1978 |
James MN, Delbaere LT, Brayer GD. Amino acid sequence alignment of bacterial and mammalian pancreatic serine proteases based on topological equivalences. Canadian Journal of Biochemistry. 56: 396-402. PMID 96920 DOI: 10.1139/O78-062 |
0.666 |
|
| 1978 |
Tang J, James MN, Hsu IN, Jenkins JA, Blundell TL. Structural evidence for gene duplication in the evolution of the acid proteases. Nature. 271: 618-21. PMID 24179 DOI: 10.1038/271618A0 |
0.535 |
|
| 1977 |
James MN, Hsu IN, Delbaere LT. Mechanism of acid protease catalysis based on the crystal structure of penicillopepsin. Nature. 267: 808-13. PMID 895839 DOI: 10.1038/267808A0 |
0.659 |
|
| 1977 |
Hsu IN, Delbaere LT, James MN, Hofmann T. Penicillopepsin: 2.8 A structure, active site conformation and mechanistic implications. Advances in Experimental Medicine and Biology. 95: 61-81. PMID 339694 DOI: 10.1007/978-1-4757-0719-9_5 |
0.703 |
|
| 1977 |
Hsu IN, Delbaere LT, James MN, Hofmann T. Penicillopepsin from Penicillium janthinellum crystal structure at 2.8 A and sequence homology with porcine pepsin. Nature. 266: 140-5. PMID 323722 DOI: 10.1038/266140A0 |
0.682 |
|
| 1975 |
Delbaere LT, Hutcheon WL, James MN, Thiessen WE. Tertiary structural differences between microbial serine proteases and pancreatic serine enzymes. Nature. 257: 758-63. PMID 1186854 DOI: 10.1038/257758A0 |
0.665 |
|
| 1974 |
Codding PW, Delbaere LT, Hayakawa K, Hutcheon WL, James MN, Jurásek L. The 4.5 Angstrom resolution structure of a bacterial serine protease from Streptomyces griseus. Canadian Journal of Biochemistry. 52: 208-20. PMID 4208242 DOI: 10.1139/O74-034 |
0.64 |
|
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