Ralph Weissleder - Publications

Center for Systems Biology Harvard Medical School, Boston, MA, United States 

91 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Ng TSC, Garlin MA, Weissleder R, Miller MA. Improving nanotherapy delivery and action through image-guided systems pharmacology. Theranostics. 10: 968-997. PMID 31938046 DOI: 10.7150/thno.37215  0.32
2020 Koch PD, Rodell CB, Kohler RH, Pittet MJ, Weissleder R. Myeloid Cell-Targeted Nanocarriers Efficiently Inhibit Cellular Inhibitor of Apoptosis for Cancer Immunotherapy. Cell Chemical Biology. 27: 94-104.e5. PMID 31902676 DOI: 10.1016/j.chembiol.2019.12.007  0.48
2019 Koch PD, Ahmed MS, Kohler RH, Li R, Weissleder R. Imaging of Tie2 with a fluorescently labeled small molecule affinity ligand. Acs Chemical Biology. PMID 31809013 DOI: 10.1021/acschembio.9b00724  0.48
2019 Liao HW, Garris C, Pfirschke C, Rickelt S, Arlauckas S, Siwicki M, Kohler RH, Weissleder R, Sundvold-Gjerstad V, Sveinbjørnsson B, Rekdal Ø, Pittet MJ. LTX-315 sequentially promotes lymphocyte-independent and lymphocyte-dependent antitumor effects. Cell Stress. 3: 348-360. PMID 31799501 DOI: 10.15698/cst2019.11.204  0.48
2019 Vinegoni C, Feruglio PF, Weissleder R. High dynamic range fluorescence imaging. Ieee Journal of Selected Topics in Quantum Electronics : a Publication of the Ieee Lasers and Electro-Optics Society. 25. PMID 31598059 DOI: 10.1109/JSTQE.2018.2881608  0.44
2019 Li R, Attari A, Prytyskach M, Garlin MA, Weissleder R, Miller MA. Single-Cell Intravital Microscopy of Trastuzumab Quantifies Heterogeneous in vivo Kinetics. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. PMID 31423731 DOI: 10.1002/cyto.a.23872  0.32
2019 Ahmed MS, Rodell CB, Hulsmans M, Kohler RH, Aguirre A, Nahrendorf M, Weissleder R. A Supramolecular Nanocarrier for Delivery of Amiodarone Anti-Arrhythmic Therapy to the Heart. Bioconjugate Chemistry. PMID 30615425 DOI: 10.1021/acs.bioconjchem.8b00882  0.48
2018 Rodell CB, Arlauckas SP, Cuccarese MF, Garris CS, Li R, Ahmed MS, Kohler RH, Pittet MJ, Weissleder R. TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy. Nature Biomedical Engineering. 2: 578-588. PMID 31015631 DOI: 10.1038/s41551-018-0236-8  0.48
2018 Arlauckas SP, Garren SB, Garris CS, Kohler RH, Oh J, Pittet MJ, Weissleder R. Arg1 expression defines immunosuppressive subsets of tumor-associated macrophages. Theranostics. 8: 5842-5854. PMID 30613266 DOI: 10.7150/thno.26888  0.48
2018 Fraser K, Jo A, Giedt J, Vinegoni C, Yang KS, Peruzzi P, Chiocca EA, Breakefield XO, Lee H, Weissleder R. Characterization of single microvesicles in plasma from glioblastoma patients. Neuro-Oncology. PMID 30561734 DOI: 10.1093/neuonc/noy187  0.44
2018 Garris CS, Arlauckas SP, Kohler RH, Trefny MP, Garren S, Piot C, Engblom C, Pfirschke C, Siwicki M, Gungabeesoon J, Freeman GJ, Warren SE, Ong S, Browning E, Twitty CG, ... ... Weissleder R, et al. Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-γ and IL-12. Immunity. PMID 30552023 DOI: 10.1016/j.immuni.2018.09.024  0.48
2018 Miller MA, Mikula H, Luthria G, Li R, Kronister S, Prytyskach M, Kohler RH, Mitchison T, Weissleder R. Modular Nanoparticulate Prodrug Design Enables Efficient Treatment of Solid Tumors Using Bioorthogonal Activation. Acs Nano. PMID 30550257 DOI: 10.1021/acsnano.8b07954  0.48
2018 Kim HY, Li R, Ng TSC, Courties G, Rodell CB, Prytyskach M, Kohler RH, Pittet M, Nahrendorf M, Weissleder R, Miller MA. Quantitative Imaging of Tumor Associated Macrophages and Their Response to Therapy Using 64Cu-Labeled Macrin. Acs Nano. PMID 30508377 DOI: 10.1021/acsnano.8b04338  0.48
2018 Pineda JJ, Miller MA, Song Y, Kuhn H, Mikula H, Tallapragada N, Weissleder R, Mitchison TJ. Site occupancy calibration of taxane pharmacology in live cells and tissues. Proceedings of the National Academy of Sciences of the United States of America. PMID 30429313 DOI: 10.1073/pnas.1800047115  0.48
2018 Giedt RJ, Pathania D, Carlson JCT, McFarland PJ, Del Castillo AF, Juric D, Weissleder R. Single-cell barcode analysis provides a rapid readout of cellular signaling pathways in clinical specimens. Nature Communications. 9: 4550. PMID 30382095 DOI: 10.1038/s41467-018-07002-6  0.48
2018 Rodell CB, Arlauckas SP, Cuccarese MF, Garris CS, Li R, Ahmed MS, Kohler RH, Pittet MJ, Weissleder R. TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy. Nature Biomedical Engineering. 2: 578-588. PMID 30345161  0.48
2018 Herisson F, Frodermann V, Courties G, Rohde D, Sun Y, Vandoorne K, Wojtkiewicz GR, Masson GS, Vinegoni C, Kim J, Kim DE, Weissleder R, Swirski FK, Moskowitz MA, Nahrendorf M. Direct vascular channels connect skull bone marrow and the brain surface enabling myeloid cell migration. Nature Neuroscience. PMID 30150661 DOI: 10.1038/s41593-018-0213-2  0.44
2018 Vandoorne K, Rohde D, Kim HY, Courties G, Wojtkiewicz GR, Honold L, Hoyer FF, Frodermann V, Nayar R, Herisson FE, Jung Y, Désogère P, Vinegoni C, Caravan P, Weissleder R, et al. Imaging the Vascular Bone Marrow Niche During Inflammatory Stress. Circulation Research. PMID 29980569 DOI: 10.1161/CIRCRESAHA.118.313302  0.44
2018 Vinegoni C, Feruglio PF, Gryczynski I, Mazitschek R, Weissleder R. Fluorescence anisotropy imaging in drug discovery. Advanced Drug Delivery Reviews. PMID 29410158 DOI: 10.1016/j.addr.2018.01.019  0.44
2018 Carlson J, Mikula H, Weissleder R. Unraveling tetrazine-triggered bioorthogonal elimination enables chemical tools for ultrafast release and universal cleavage. Journal of the American Chemical Society. PMID 29384666 DOI: 10.1021/jacs.7b11217  0.48
2018 Hulsmans M, Sager HB, Roh JD, Valero-Muñoz M, Houstis NE, Iwamoto Y, Sun Y, Wilson RM, Wojtkiewicz G, Tricot B, Osborne MT, Hung J, Vinegoni C, Naxerova K, Sosnovik DE, ... ... Weissleder R, et al. Cardiac macrophages promote diastolic dysfunction. The Journal of Experimental Medicine. PMID 29339450 DOI: 10.1084/jem.20171274  0.44
2017 Miller MA, Kim E, Cuccarese MF, Plotkin AL, Prytyskach M, Kohler RH, Pittet MJ, Weissleder R. Near infrared imaging of Mer tyrosine kinase (MERTK) using MERi-SiR reveals tumor associated macrophage uptake in metastatic disease. Chemical Communications (Cambridge, England). 54: 42-45. PMID 29185561 DOI: 10.1039/c7cc07581b  0.48
2017 King KR, Aguirre AD, Ye YX, Sun Y, Roh JD, Ng RP, Kohler RH, Arlauckas SP, Iwamoto Y, Savol A, Sadreyev RI, Kelly M, Fitzgibbons TP, Fitzgerald KA, Mitchison T, ... ... Weissleder R, et al. IRF3 and type I interferons fuel a fatal response to myocardial infarction. Nature Medicine. PMID 29106401 DOI: 10.1038/nm.4428  0.48
2017 Miller MA, Arlauckas S, Weissleder R. Prediction of Anti-cancer Nanotherapy Efficacy by Imaging. Nanotheranostics. 1: 296-312. PMID 29071194 DOI: 10.7150/ntno.20564  0.32
2017 Mohan JF, Kohler RH, Hill JA, Weissleder R, Mathis D, Benoist C. Imaging the emergence and natural progression of spontaneous autoimmune diabetes. Proceedings of the National Academy of Sciences of the United States of America. PMID 28839093 DOI: 10.1073/pnas.1707381114  0.48
2017 Miller MA, Askevold B, Mikula H, Kohler RH, Pirovich D, Weissleder R. Nano-palladium is a cellular catalyst for in vivo chemistry. Nature Communications. 8: 15906. PMID 28699627 DOI: 10.1038/ncomms15906  0.48
2017 Vinegoni C, Fumene Feruglio P, Brand C, Lee S, Nibbs AE, Stapleton S, Shah S, Gryczynski I, Reiner T, Mazitschek R, Weissleder R. Measurement of drug-target engagement in live cells by two-photon fluorescence anisotropy imaging. Nature Protocols. 12: 1472-1497. PMID 28686582 DOI: 10.1038/nprot.2017.043  0.44
2017 Miller MA, Weissleder R. Imaging of anticancer drug action in single cells. Nature Reviews. Cancer. 17: 399-414. PMID 28642603 DOI: 10.1038/nrc.2017.41  0.32
2017 Miller MA, Chandra R, Cuccarese MF, Pfirschke C, Engblom C, Stapleton S, Adhikary U, Kohler RH, Mohan JF, Pittet MJ, Weissleder R. Radiation therapy primes tumors for nanotherapeutic delivery via macrophage-mediated vascular bursts. Science Translational Medicine. 9. PMID 28566423 DOI: 10.1126/scitranslmed.aal0225  0.48
2017 Arlauckas SP, Garris CS, Kohler RH, Kitaoka M, Cuccarese MF, Yang KS, Miller MA, Carlson JC, Freeman GJ, Anthony RM, Weissleder R, Pittet MJ. In vivo imaging reveals a tumor-associated macrophage-mediated resistance pathway in anti-PD-1 therapy. Science Translational Medicine. 9. PMID 28490665 DOI: 10.1126/scitranslmed.aal3604  0.48
2017 Mikula H, Stapleton S, Kohler RH, Vinegoni C, Weissleder R. Design and Development of Fluorescent Vemurafenib Analogs for In Vivo Imaging. Theranostics. 7: 1257-1265. PMID 28435463 DOI: 10.7150/thno.18238  0.48
2017 Hulsmans M, Clauss S, Xiao L, Aguirre AD, King KR, Hanley A, Hucker WJ, Wülfers EM, Seemann G, Courties G, Iwamoto Y, Sun Y, Savol AJ, Sager HB, Lavine KJ, ... ... Weissleder R, et al. Macrophages Facilitate Electrical Conduction in the Heart. Cell. 169: 510-522.e20. PMID 28431249 DOI: 10.1016/j.cell.2017.03.050  0.44
2017 Seo KJ, Qiang Y, Bilgin I, Kar S, Vinegoni C, Weissleder R, Fang H. Transparent Electrophysiology Microelectrodes and Interconnects from Metal Nanomesh. Acs Nano. PMID 28391679 DOI: 10.1021/acsnano.7b01995  0.44
2017 Lee S, Courties G, Nahrendorf M, Weissleder R, Vinegoni C. Motion characterization scheme to minimize motion artifacts in intravital microscopy. Journal of Biomedical Optics. 22: 36005. PMID 28253383 DOI: 10.1117/1.JBO.22.3.036005  0.44
2017 Cuccarese MF, Dubach JM, Pfirschke C, Engblom C, Garris C, Miller MA, Pittet MJ, Weissleder R. Heterogeneity of macrophage infiltration and therapeutic response in lung carcinoma revealed by 3D organ imaging. Nature Communications. 8: 14293. PMID 28176769 DOI: 10.1038/ncomms14293  0.32
2016 Dubach JM, Kim E, Yang K, Cuccarese M, Giedt RJ, Meimetis LG, Vinegoni C, Weissleder R. Quantitating drug-target engagement in single cells in vitro and in vivo. Nature Chemical Biology. PMID 27918558 DOI: 10.1038/nchembio.2248  0.48
2016 Giedt RJ, Fumene Feruglio P, Pathania D, Yang KS, Kilcoyne A, Vinegoni C, Mitchison TJ, Weissleder R. Computational imaging reveals mitochondrial morphology as a biomarker of cancer phenotype and drug response. Scientific Reports. 6: 32985. PMID 27609668 DOI: 10.1038/srep32985  0.48
2016 Vinegoni C, Dubach JM, Feruglio PF, Weissleder R. Two-photon Fluorescence Anisotropy Microscopy for Imaging and Direct Measurement of Intracellular Drug Target Engagement. Ieee Journal of Selected Topics in Quantum Electronics : a Publication of the Ieee Lasers and Electro-Optics Society. 22. PMID 27440991 DOI: 10.1109/JSTQE.2015.2501384  0.44
2016 Meimetis LG, Giedt RJ, Mikula H, Carlson JC, Kohler RH, Pirovich DB, Weissleder R. Fluorescent vinblastine probes for live cell imaging. Chemical Communications (Cambridge, England). PMID 27439765 DOI: 10.1039/c6cc04129a  0.48
2016 Sager HB, Dutta P, Dahlman JE, Hulsmans M, Courties G, Sun Y, Heidt T, Vinegoni C, Borodovsky A, Fitzgerald K, Wojtkiewicz GR, Iwamoto Y, Tricot B, Khan OF, Kauffman KJ, ... ... Weissleder R, et al. RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarction. Science Translational Medicine. 8: 342ra80. PMID 27280687 DOI: 10.1126/scitranslmed.aaf1435  0.44
2016 Miller MA, Weissleder R. Imaging the pharmacology of nanomaterials by intravital microscopy: Towards understanding their biological behavior. Advanced Drug Delivery Reviews. PMID 27266447 DOI: 10.1016/j.addr.2016.05.023  0.32
2016 Miller MA, Oudin MJ, Sullivan RJ, Wang SJ, Meyer AS, Im H, Frederick DT, Tadros J, Griffith LG, Lee H, Weissleder R, Flaherty KT, Gertler FB, Lauffenburger DA. Reduced Proteolytic Shedding of Receptor Tyrosine Kinases Is a Post-Translational Mechanism of Kinase Inhibitor Resistance. Cancer Discovery. PMID 26984351 DOI: 10.1158/2159-8290.CD-15-0933  0.32
2016 Im H, Park YI, Pathania D, Castro CM, Weissleder R, Lee H. Digital diffraction detection of protein markers for avian influenza. Lab On a Chip. PMID 26980325 DOI: 10.1039/c5lc01558h  0.48
2016 Roy J, Kim B, Hill E, Visconti P, Krapf D, Vinegoni C, Weissleder R, Brown D, Breton S. Tyrosine kinase-mediated axial motility of basal cells revealed by intravital imaging. Nature Communications. 7: 10666. PMID 26868824 DOI: 10.1038/ncomms10666  0.44
2015 Hong S, Carlson J, Lee H, Weissleder R. Bioorthogonal Radiopaque Hydrogel for Endoscopic Delivery and Universal Tissue Marking. Advanced Healthcare Materials. PMID 26688173 DOI: 10.1002/adhm.201500780  0.48
2015 Meimetis LG, Boros E, Carlson JC, Ran C, Caravan P, Weissleder R. Bioorthogonal fluorophore linked DFO - Technology enabling facile chelator quantification and multimodal imaging of antibodies. Bioconjugate Chemistry. PMID 26684717 DOI: 10.1021/acs.bioconjchem.5b00630  0.48
2015 Miller MA, Gadde S, Pfirschke C, Engblom C, Sprachman MM, Kohler RH, Yang KS, Laughney AM, Wojtkiewicz G, Kamaly N, Bhonagiri S, Pittet MJ, Farokhzad OC, Weissleder R. Predicting therapeutic nanomedicine efficacy using a companion magnetic resonance imaging nanoparticle. Science Translational Medicine. 7: 314ra183. PMID 26582898 DOI: 10.1126/scitranslmed.aac6522  0.48
2015 Miller MA, Zheng YR, Gadde S, Pfirschke C, Zope H, Engblom C, Kohler RH, Iwamoto Y, Yang KS, Askevold B, Kolishetti N, Pittet M, Lippard SJ, Farokhzad OC, Weissleder R. Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug. Nature Communications. 6: 8692. PMID 26503691 DOI: 10.1038/ncomms9692  0.48
2015 Vinegoni C, Aguirre AD, Lee S, Weissleder R. Imaging the beating heart in the mouse using intravital microscopy techniques. Nature Protocols. 10: 1802-1819. PMID 26492138 DOI: 10.1038/nprot.2015.119  0.44
2015 Park KS, Charles RC, Ryan ET, Weissleder R, Lee H. Fluorescence Polarization Based Nucleic Acid Testing for Rapid and Cost-Effective Diagnosis of Infectious Disease. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 26420633 DOI: 10.1002/chem.201502934  0.48
2015 Clardy SM, Mohan JF, Vinegoni C, Keliher EJ, Iwamoto Y, Benoist C, Mathis D, Weissleder R. Rapid, high efficiency isolation of pancreatic ß-cells. Scientific Reports. 5: 13681. PMID 26330153 DOI: 10.1038/srep13681  0.44
2015 Chung HJ, Pellegrini KL, Chung J, Wanigasuriya K, Jayawardene I, Lee K, Lee H, Vaidya VS, Weissleder R. Nanoparticle Detection of Urinary Markers for Point-of-Care Diagnosis of Kidney Injury. Plos One. 10: e0133417. PMID 26186708 DOI: 10.1371/journal.pone.0133417  0.48
2015 Abazari A, Meimetis LG, Budin G, Bale SS, Weissleder R, Toner M. Engineered Trehalose Permeable to Mammalian Cells. Plos One. 10: e0130323. PMID 26115179 DOI: 10.1371/journal.pone.0130323  0.48
2015 Park YI, Im H, Weissleder R, Lee H. Nanostar clustering improves the sensitivity of plasmonic assays. Bioconjugate Chemistry. PMID 26102604 DOI: 10.1021/acs.bioconjchem.5b00343  0.48
2015 Glenn DR, Lee K, Park H, Weissleder R, Yacoby A, Lukin MD, Lee H, Walsworth RL, Connolly CB. Single-cell magnetic imaging using a quantum diamond microscope. Nature Methods. PMID 26098019 DOI: 10.1038/nmeth.3449  0.48
2015 Tawakol A, Hara T, Truelove J, Wojtkiewicz GR, Hucker WJ, MacNabb MH, Brownell AL, Jokivarsi K, Kessinger CW, Jaff MR, Henke PK, Weissleder R, Jaffer FA. Response to Letter Regarding Article, "18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Enables the Detection of Recurrent Same-Site Deep Vein Thrombosis by Illuminating Recently Formed, Neutrophil-Rich Thrombus". Circulation. 131: e531-2. PMID 26078375 DOI: 10.1161/CIRCULATIONAHA.115.014802  0.48
2015 Vinegoni C, Lee S, Aguirre AD, Weissleder R. New techniques for motion-artifact-free in vivo cardiac microscopy. Frontiers in Physiology. 6: 147. PMID 26029116 DOI: 10.3389/fphys.2015.00147  0.44
2015 Vinegoni C, Dubach JM, Thurber GM, Miller MA, Mazitschek R, Weissleder R. Advances in measuring single-cell pharmacology in vivo. Drug Discovery Today. 20: 1087-92. PMID 26024776 DOI: 10.1016/j.drudis.2015.05.011  0.44
2015 Kim E, Yang KS, Kohler RH, Dubach JM, Mikula H, Weissleder R. Optimized Near-IR Fluorescent Agents for in Vivo Imaging of Btk Expression. Bioconjugate Chemistry. PMID 26017814 DOI: 10.1021/acs.bioconjchem.5b00152  0.48
2015 Turetsky A, Lee K, Song J, Giedt RJ, Kim E, Kovach AE, Hochberg EP, Castro CM, Lee H, Weissleder R. On chip analysis of CNS lymphoma in cerebrospinal fluid. Theranostics. 5: 796-804. PMID 26000053 DOI: 10.7150/thno.11220  0.48
2015 Yang KS, Kohler RH, Landon M, Giedt R, Weissleder R. Single cell resolution in vivo imaging of DNA damage following PARP inhibition. Scientific Reports. 5: 10129. PMID 25984718 DOI: 10.1038/srep10129  0.48
2015 Lai CP, Kim EY, Badr CE, Weissleder R, Mempel TR, Tannous BA, Breakefield XO. Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters. Nature Communications. 6: 7029. PMID 25967391 DOI: 10.1038/ncomms8029  0.48
2015 Shao H, Chung J, Lee K, Balaj L, Min C, Carter BS, Hochberg FH, Breakefield XO, Lee H, Weissleder R. Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma. Nature Communications. 6: 6999. PMID 25959588 DOI: 10.1038/ncomms7999  0.48
2015 Dutta P, Sager HB, Stengel KR, Naxerova K, Courties G, Saez B, Silberstein L, Heidt T, Sebas M, Sun Y, Wojtkiewicz G, Feruglio PF, King K, Baker JN, van der Laan AM, ... ... Weissleder R, et al. Myocardial Infarction Activates CCR2(+) Hematopoietic Stem and Progenitor Cells. Cell Stem Cell. 16: 477-87. PMID 25957903 DOI: 10.1016/j.stem.2015.04.008  0.48
2015 Rashidian M, Keliher EJ, Bilate AM, Duarte JN, Wojtkiewicz GR, Jacobsen JT, Cragnolini J, Swee LK, Victora GD, Weissleder R, Ploegh HL. Noninvasive imaging of immune responses. Proceedings of the National Academy of Sciences of the United States of America. 112: 6146-51. PMID 25902531 DOI: 10.1073/pnas.1502609112  0.48
2015 Im H, Castro CM, Shao H, Liong M, Song J, Pathania D, Fexon L, Min C, Avila-Wallace M, Zurkiya O, Rho J, Magaoay B, Tambouret RH, Pivovarov M, Weissleder R, et al. Digital diffraction analysis enables low-cost molecular diagnostics on a smartphone. Proceedings of the National Academy of Sciences of the United States of America. 112: 5613-8. PMID 25870273 DOI: 10.1073/pnas.1501815112  0.48
2015 Chittajallu DR, Florian S, Kohler RH, Iwamoto Y, Orth JD, Weissleder R, Danuser G, Mitchison TJ. In vivo cell-cycle profiling in xenograft tumors by quantitative intravital microscopy. Nature Methods. 12: 577-85. PMID 25867850 DOI: 10.1038/nmeth.3363  0.48
2015 Dutta P, Hoyer FF, Grigoryeva LS, Sager HB, Leuschner F, Courties G, Borodovsky A, Novobrantseva T, Ruda VM, Fitzgerald K, Iwamoto Y, Wojtkiewicz G, Sun Y, Da Silva N, Libby P, ... ... Weissleder R, et al. Macrophages retain hematopoietic stem cells in the spleen via VCAM-1. The Journal of Experimental Medicine. 212: 497-512. PMID 25800955 DOI: 10.1084/jem.20141642  0.48
2015 Nair AV, Keliher EJ, Core AB, Brown D, Weissleder R. Characterizing the interactions of organic nanoparticles with renal epithelial cells in vivo. Acs Nano. 9: 3641-53. PMID 25790730 DOI: 10.1021/acsnano.5b00428  0.48
2015 Weber GF, Chousterman BG, He S, Fenn AM, Nairz M, Anzai A, Brenner T, Uhle F, Iwamoto Y, Robbins CS, Noiret L, Maier SL, Zönnchen T, Rahbari NN, Schölch S, ... ... Weissleder R, et al. Interleukin-3 amplifies acute inflammation and is a potential therapeutic target in sepsis. Science (New York, N.Y.). 347: 1260-5. PMID 25766237 DOI: 10.1126/science.aaa4268  0.48
2015 Chen S, Sanjana NE, Zheng K, Shalem O, Lee K, Shi X, Scott DA, Song J, Pan JQ, Weissleder R, Lee H, Zhang F, Sharp PA. Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis. Cell. 160: 1246-60. PMID 25748654 DOI: 10.1016/j.cell.2015.02.038  0.48
2015 Kessinger CW, Kim JW, Henke PK, Thompson B, McCarthy JR, Hara T, Sillesen M, Margey RJ, Libby P, Weissleder R, Lin CP, Jaffer FA. Statins improve the resolution of established murine venous thrombosis: reductions in thrombus burden and vein wall scarring. Plos One. 10: e0116621. PMID 25680183 DOI: 10.1371/journal.pone.0116621  0.48
2015 Gaglia JL, Harisinghani M, Aganj I, Wojtkiewicz GR, Hedgire S, Benoist C, Mathis D, Weissleder R. Noninvasive mapping of pancreatic inflammation in recent-onset type-1 diabetes patients. Proceedings of the National Academy of Sciences of the United States of America. 112: 2139-44. PMID 25650428 DOI: 10.1073/pnas.1424993112  0.48
2015 Magnuson AM, Thurber GM, Kohler RH, Weissleder R, Mathis D, Benoist C. Population dynamics of islet-infiltrating cells in autoimmune diabetes. Proceedings of the National Academy of Sciences of the United States of America. 112: 1511-6. PMID 25605891 DOI: 10.1073/pnas.1423769112  0.48
2015 Langer R, Weissleder R. Nanotechnology Jama - Journal of the American Medical Association. 313: 135-136. PMID 25585320 DOI: 10.1001/jama.2014.16315  0.48
2015 Courties G, Herisson F, Sager HB, Heidt T, Ye Y, Wei Y, Sun Y, Severe N, Dutta P, Scharff J, Scadden DT, Weissleder R, Swirski FK, Moskowitz MA, Nahrendorf M. Ischemic stroke activates hematopoietic bone marrow stem cells. Circulation Research. 116: 407-17. PMID 25362208 DOI: 10.1161/CIRCRESAHA.116.305207  0.48
2015 Alagesan B, Contino G, Guimaraes AR, Corcoran RB, Deshpande V, Wojtkiewicz GR, Hezel AF, Wong KK, Loda M, Weissleder R, Benes C, Engelman JA, Bardeesy N. Combined MEK and PI3K inhibition in a mouse model of pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 396-404. PMID 25348516 DOI: 10.1158/1078-0432.CCR-14-1591  0.48
2014 Alieva M, Ritsma L, Giedt RJ, Weissleder R, van Rheenen J. Imaging windows for long-term intravital imaging: General overview and technical insights. Intravital. 3: e29917. PMID 28243510 DOI: 10.4161/intv.29917  0.48
2014 Shen K, Luk S, Hicks DF, Elman JS, Bohr S, Iwamoto Y, Murray R, Pena K, Wang F, Seker E, Weissleder R, Yarmush ML, Toner M, Sgroi D, Parekkadan B. Resolving cancer-stroma interfacial signalling and interventions with micropatterned tumour-stromal assays. Nature Communications. 5: 5662. PMID 25489927 DOI: 10.1038/ncomms6662  0.48
2014 Fu W, Farache J, Clardy SM, Hattori K, Mander P, Lee K, Rioja I, Weissleder R, Prinjha RK, Benoist C, Mathis D. Epigenetic modulation of type-1 diabetes via a dual effect on pancreatic macrophages and β cells. Elife. 3: e04631. PMID 25407682 DOI: 10.7554/eLife.04631  0.48
2014 Laughney AM, Kim E, Sprachman MM, Miller MA, Kohler RH, Yang KS, Orth JD, Mitchison TJ, Weissleder R. Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin. Science Translational Medicine. 6: 261ra152. PMID 25378644 DOI: 10.1126/scitranslmed.3009318  0.48
2014 Giedt RJ, Sprachman MM, Yang KS, Weissleder R. Imaging cellular distribution of Bcl inhibitors using small molecule drug conjugates. Bioconjugate Chemistry. 25: 2081-5. PMID 25333750 DOI: 10.1021/bc500433k  0.48
2014 Taqueti VR, Di Carli MF, Jerosch-Herold M, Sukhova GK, Murthy VL, Folco EJ, Kwong RY, Ozaki CK, Belkin M, Nahrendorf M, Weissleder R, Libby P. Increased microvascularization and vessel permeability associate with active inflammation in human atheromata. Circulation. Cardiovascular Imaging. 7: 920-9. PMID 25170063 DOI: 10.1161/CIRCIMAGING.114.002113  0.48
2014 Dubach JM, Vinegoni C, Weissleder R. Steady state anisotropy two-photon microscopy resolves multiple, spectrally similar fluorophores, enabling in vivo multilabel imaging. Optics Letters. 39: 4482-5. PMID 25078208  0.44
2014 Hara T, Truelove J, Tawakol A, Wojtkiewicz GR, Hucker WJ, MacNabb MH, Brownell AL, Jokivarsi K, Kessinger CW, Jaff MR, Henke PK, Weissleder R, Jaffer FA. 18F-fluorodeoxyglucose positron emission tomography/computed tomography enables the detection of recurrent same-site deep vein thrombosis by illuminating recently formed, neutrophil-rich thrombus. Circulation. 130: 1044-52. PMID 25070665 DOI: 10.1161/CIRCULATIONAHA.114.008902  0.48
2014 Aguirre AD, Vinegoni C, Sebas M, Weissleder R. Intravital imaging of cardiac function at the single-cell level. Proceedings of the National Academy of Sciences of the United States of America. 111: 11257-62. PMID 25053815 DOI: 10.1073/pnas.1401316111  0.44
2014 Stangenberg L, Burzyn D, Binstadt BA, Weissleder R, Mahmood U, Benoist C, Mathis D. Denervation protects limbs from inflammatory arthritis via an impact on the microvasculature. Proceedings of the National Academy of Sciences of the United States of America. 111: 11419-24. PMID 25049388 DOI: 10.1073/pnas.1410854111  0.48
2014 Heidt T, Sager HB, Courties G, Dutta P, Iwamoto Y, Zaltsman A, von Zur Muhlen C, Bode C, Fricchione GL, Denninger J, Lin CP, Vinegoni C, Libby P, Swirski FK, Weissleder R, et al. Chronic variable stress activates hematopoietic stem cells. Nature Medicine. 20: 754-8. PMID 24952646 DOI: 10.1038/nm.3589  0.48
2014 Meimetis LG, Carlson JC, Giedt RJ, Kohler RH, Weissleder R. Ultrafluorogenic coumarin-tetrazine probes for real-time biological imaging. Angewandte Chemie (International Ed. in English). 53: 7531-4. PMID 24915832 DOI: 10.1002/anie.201403890  0.48
2014 Weber GF, Chousterman BG, Hilgendorf I, Robbins CS, Theurl I, Gerhardt LM, Iwamoto Y, Quach TD, Ali M, Chen JW, Rothstein TL, Nahrendorf M, Weissleder R, Swirski FK. Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis. The Journal of Experimental Medicine. 211: 1243-56. PMID 24821911 DOI: 10.1084/jem.20131471  0.48
2014 Sprachman MM, Laughney AM, Kohler RH, Weissleder R. In vivo imaging of multidrug resistance using a third generation MDR1 inhibitor. Bioconjugate Chemistry. 25: 1137-42. PMID 24806886 DOI: 10.1021/bc500154c  0.48
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