Jean-Michel Heard, PhD - Publications

Affiliations: 
Institut Pasteur, Paris, Paris, France 

64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Tardieu M, Zérah M, Husson B, de Bournonville S, Deiva K, Adamsbaum C, Vincent F, Hocquemiller M, Broissand C, Furlan V, Ballabio A, Fraldi A, Crystal RG, Baugnon T, Roujeau T, ... Heard JM, et al. Intracerebral administration of adeno-associated viral vector serotype rh.10 carrying human SGSH and SUMF1 cDNAs in children with mucopolysaccharidosis type IIIA disease: results of a phase I/II trial. Human Gene Therapy. 25: 506-16. PMID 24524415 DOI: 10.1089/Hum.2013.238  0.485
2011 Héron B, Mikaeloff Y, Froissart R, Caridade G, Maire I, Caillaud C, Levade T, Chabrol B, Feillet F, Ogier H, Valayannopoulos V, Michelakakis H, Zafeiriou D, Lavery L, Wraith E, ... ... Heard JM, et al. Incidence and natural history of mucopolysaccharidosis type III in France and comparison with United Kingdom and Greece. American Journal of Medical Genetics. Part A. 155: 58-68. PMID 21204211 DOI: 10.1002/Ajmg.A.33779  0.508
2011 Ellinwood NM, Ausseil J, Desmaris N, Bigou S, Liu S, Jens JK, Snella EM, Mohammed EE, Thomson CB, Raoul S, Joussemet B, Roux F, Chérel Y, Lajat Y, Piraud M, ... ... Heard JM, et al. Safe, efficient, and reproducible gene therapy of the brain in the dog models of Sanfilippo and Hurler syndromes. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 251-9. PMID 21139569 DOI: 10.1038/Mt.2010.265  0.735
2009 Ciron C, Cressant A, Roux F, Raoul S, Cherel Y, Hantraye P, Déglon N, Schwartz B, Barkats M, Heard JM, Tardieu M, Moullier P, Colle MA. Human alpha-iduronidase gene transfer mediated by adeno-associated virus types 1, 2, and 5 in the brain of nonhuman primates: vector diffusion and biodistribution. Human Gene Therapy. 20: 350-60. PMID 19272011 DOI: 10.1089/Hum.2008.155  0.535
2008 Ausseil J, Desmaris N, Bigou S, Attali R, Corbineau S, Vitry S, Parent M, Cheillan D, Fuller M, Maire I, Vanier MT, Heard JM. Early neurodegeneration progresses independently of microglial activation by heparan sulfate in the brain of mucopolysaccharidosis IIIB mice. Plos One. 3: e2296. PMID 18509511 DOI: 10.1371/Journal.Pone.0002296  0.329
2006 Ciron C, Desmaris N, Colle MA, Raoul S, Joussemet B, Vérot L, Ausseil J, Froissart R, Roux F, Chérel Y, Ferry N, Lajat Y, Schwartz B, Vanier MT, Maire I, ... ... Heard JM, et al. Gene therapy of the brain in the dog model of Hurler's syndrome. Annals of Neurology. 60: 204-13. PMID 16718701 DOI: 10.1002/Ana.20870  0.604
2006 Chen F, Vitry S, Hocquemiller M, Desmaris N, Ausseil J, Heard JM. alpha-L-Iduronidase transport in neurites. Molecular Genetics and Metabolism. 87: 349-58. PMID 16439176 DOI: 10.1016/J.Ymgme.2005.11.017  0.347
2002 Favre D, Blouin V, Provost N, Spisek R, Porrot F, Bohl D, Marmé F, Chérel Y, Salvetti A, Hurtrel B, Heard JM, Rivière Y, Moullier P. Lack of an immune response against the tetracycline-dependent transactivator correlates with long-term doxycycline-regulated transgene expression in nonhuman primates after intramuscular injection of recombinant adeno-associated virus. Journal of Virology. 76: 11605-11. PMID 12388721 DOI: 10.1128/Jvi.76.22.11605-11611.2002  0.577
2002 Sol-Foulon N, Moris A, Nobile C, Boccaccio C, Engering A, Abastado JP, Heard JM, van Kooyk Y, Schwartz O. HIV-1 Nef-induced upregulation of DC-SIGN in dendritic cells promotes lymphocyte clustering and viral spread. Immunity. 16: 145-55. PMID 11825573 DOI: 10.1016/S1074-7613(02)00260-1  0.521
2001 Maréchal V, Prevost MC, Petit C, Perret E, Heard JM, Schwartz O. Human immunodeficiency virus type 1 entry into macrophages mediated by macropinocytosis. Journal of Virology. 75: 11166-77. PMID 11602756 DOI: 10.1128/Jvi.75.22.11166-11177.2001  0.503
2001 Desmaris N, Bosch A, Salaün C, Petit C, Prévost MC, Tordo N, Perrin P, Schwartz O, de Rocquigny H, Heard JM. Production and neurotropism of lentivirus vectors pseudotyped with lyssavirus envelope glycoproteins. Molecular Therapy : the Journal of the American Society of Gene Therapy. 4: 149-56. PMID 11482987 DOI: 10.1006/Mthe.2001.0431  0.479
2001 Petit C, Buseyne F, Boccaccio C, Abastado JP, Heard JM, Schwartz O. Nef is required for efficient HIV-1 replication in cocultures of dendritic cells and lymphocytes. Virology. 286: 225-36. PMID 11448175 DOI: 10.1006/Viro.2001.0984  0.543
2001 Buseyne F, Le Gall S, Boccaccio C, Abastado JP, Lifson JD, Arthur LO, Rivière Y, Heard JM, Schwartz O. MHC-I-restricted presentation of HIV-1 virion antigens without viral replication. Nature Medicine. 7: 344-9. PMID 11231634 DOI: 10.1038/85493  0.56
2001 Byun J, Heard JM, Huh JE, Park SJ, Jung EA, Jeong JO, Gwon HC, Kim DK. Efficient expression of the vascular endothelial growth factor gene in vitro and in vivo, using an adeno-associated virus vector. Journal of Molecular and Cellular Cardiology. 33: 295-305. PMID 11162134 DOI: 10.1006/Jmcc.2000.1301  0.34
2000 Le Gall S, Buseyne F, Trocha A, Walker BD, Heard JM, Schwartz O. Distinct trafficking pathways mediate Nef-induced and clathrin-dependent major histocompatibility complex class I down-regulation. Journal of Virology. 74: 9256-66. PMID 10982373 DOI: 10.1128/Jvi.74.19.9256-9266.2000  0.453
2000 Byun J, Kim SH, Kim SZ, Heard JM, Huh JE, Choe YH, Park SJ, Jung EA, Kim DK. Ectopic expression of active processed form of atrial natriuretic peptide in skeletal myoblasts. Biochemical and Biophysical Research Communications. 270: 637-42. PMID 10753676 DOI: 10.1006/Bbrc.2000.2468  0.339
2000 Heard J, Danos O, Peschanski M. Réflexions sur l'avenir de la thérapie génique. MéDecine/Sciences. 16: 1305. DOI: 10.4267/10608/1582  0.408
2000 Heard JM, Danos O, Peschanski M. Where does gene therapy go? | Reflexions sur l'avenir de la therapie genique Medecine/Sciences. 16: 1305-1309.  0.468
1999 Maréchal V, Arenzana-Seisdedos F, Heard JM, Schwartz O. Opposite effects of SDF-1 on human immunodeficiency virus type 1 replication. Journal of Virology. 73: 3608-15. PMID 10196252 DOI: 10.1128/Jvi.73.5.3608-3615.1999  0.502
1998 Le Gall S, Erdtmann L, Benichou S, Berlioz-Torrent C, Liu L, Benarous R, Heard JM, Schwartz O. Nef interacts with the mu subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC I molecules. Immunity. 8: 483-95. PMID 9586638 DOI: 10.1016/S1074-7613(00)80553-1  0.509
1998 Schwartz O, Maréchal V, Friguet B, Arenzana-Seisdedos F, Heard JM. Antiviral activity of the proteasome on incoming human immunodeficiency virus type 1. Journal of Virology. 72: 3845-50. PMID 9557668 DOI: 10.1128/Jvi.72.5.3845-3850.1998  0.512
1998 Maréchal V, Clavel F, Heard JM, Schwartz O. Cytosolic Gag p24 as an index of productive entry of human immunodeficiency virus type 1. Journal of Virology. 72: 2208-12. PMID 9499078 DOI: 10.1128/Jvi.72.3.2208-2212.1998  0.492
1998 Battini JL, Danos O, Heard JM. Definition of a 14-amino-acid peptide essential for the interaction between the murine leukemia virus amphotropic envelope glycoprotein and its receptor. Journal of Virology. 72: 428-35. PMID 9420242  0.469
1997 Ferry N, Branchereau S, Heard JM, Danos O. In situ retrovirus-mediated gene transfer into the liver. Methods in Molecular Medicine. 7: 195-204. PMID 24493427 DOI: 10.1385/0-89603-484-4:195  0.549
1997 Le Gall S, Prevost MC, Heard JM, Schwartz O. Human immunodeficiency virus type I Nef independently affects virion incorporation of major histocompatibility complex class I molecules and virus infectivity. Virology. 229: 295-301. PMID 9123874 DOI: 10.1006/Viro.1996.8417  0.541
1997 Le Gall S, Heard JM, Schwartz O. Analysis of Nef-induced MHC-I endocytosis. Research in Virology. 148: 43-7. PMID 9017833 DOI: 10.1016/S0923-2516(97)81912-7  0.405
1996 Moullier P, Salvetti A, Bohl D, Danos O, Heard JM. [Gene therapy in lysosomal diseases]. Comptes Rendus Des SéAnces De La SociéTé De Biologie Et De Ses Filiales. 190: 45-51. PMID 8881268  0.521
1996 Naffakh N, Pinset C, Montarras D, Li Z, Paulin D, Danos O, Heard JM. Long-term secretion of therapeutic proteins from genetically modified skeletal muscles. Human Gene Therapy. 7: 11-21. PMID 8825864 DOI: 10.1089/hum.1996.7.1-11  0.505
1996 Moullier P, Salvetti A, Bohl D, Danos O, Heard JM. [Gene therapy of lysosomal diseases]. Archives De PéDiatrie : Organe Officiel De La SociéTe FrançAise De PéDiatrie. 3: 65s-68s. PMID 8795971 DOI: 10.1016/0929-693X(96)85996-3  0.633
1996 Oberlin E, Amara A, Bachelerie F, Bessia C, Virelizier JL, Arenzana-Seisdedos F, Schwartz O, Heard JM, Clark-Lewis I, Legler DF, Loetscher M, Baggiolini M, Moser B. The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1. Nature. 382: 833-5. PMID 8752281 DOI: 10.1038/382833A0  0.564
1996 Champseix C, Maréchal V, Khazaal I, Schwartz O, Fournier S, Schlegel N, Dranoff G, Danos O, Blot P, Vilmer E, Heard JM, Péault B, Lehn P. A cell surface marker gene transferred with a retroviral vector into CD34+ cord blood cells is expressed by their T-cell progeny in the SCID-hu thymus. Blood. 88: 107-13. PMID 8704164  0.656
1996 Battini JL, Rodrigues P, Müller R, Danos O, Heard JM. Receptor-binding properties of a purified fragment of the 4070A amphotropic murine leukemia virus envelope glycoprotein. Journal of Virology. 70: 4387-93. PMID 8676462  0.497
1996 Schwartz O, Maréchal V, Le Gall S, Lemonnier F, Heard JM. Endocytosis of major histocompatibility complex class I molecules is induced by the HIV-1 Nef protein. Nature Medicine. 2: 338-42. PMID 8612235 DOI: 10.1038/nm0396-338  0.519
1996 Lavau C, Heard JM, Danos O, Dejean A. Retroviral vectors for the transduction of the PML-RARalpha fusion product of acute promyelocytic leukemia. Experimental Hematology. 24: 544-51. PMID 8608805  0.513
1996 Hacein-Bey H, Cavazzana-Calvo M, Le Deist F, Dautry-Varsat A, Hivroz C, Rivière I, Danos O, Heard JM, Sugamura K, Fischer A, De Saint Basile G. gamma-c gene transfer into SCID X1 patients' B-cell lines restores normal high-affinity interleukin-2 receptor expression and function. Blood. 87: 3108-16. PMID 8605324  0.49
1996 Mouiller P, Salvetti A, Bohl D, Danos O, Heard JM. Thérapie génique des maladies lysosomales Archives De Pediatrie. 3: 65s-68s.  0.411
1995 Naffakh N, Moullier P, Salvetti A, Bohl D, Danos O, Heard JM. Delivery of therapeutic proteins from genetically-modified cells. Restorative Neurology and Neuroscience. 8: 67-9. PMID 21551810 DOI: 10.3233/Rnn-1995-81216  0.641
1995 Danos O, Heard JM. Mucopolysaccharidosis. Molecular and Cell Biology of Human Diseases Series. 5: 350-67. PMID 9532574  0.437
1995 Carreau M, Quilliet X, Eveno E, Salvetti A, Danos O, Heard JM, Mezzina M, Sarasin A. Functional retroviral vector for gene therapy of xeroderma pigmentosum group D patients. Human Gene Therapy. 6: 1307-15. PMID 8590735 DOI: 10.1089/hum.1995.6.10-1307  0.482
1995 Salvetti A, Moullier P, Cornet V, Brooks D, Hopwood JJ, Danos O, Heard JM. In vivo delivery of human alpha-L-iduronidase in mice implanted with neo-organs. Human Gene Therapy. 6: 1153-9. PMID 8527473 DOI: 10.1089/Hum.1995.6.9-1153  0.678
1995 Schwartz O, Dautry-Varsat A, Goud B, Maréchal V, Subtil A, Heard JM, Danos O. Human immunodeficiency virus type 1 Nef induces accumulation of CD4 in early endosomes. Journal of Virology. 69: 528-33. PMID 7983750 DOI: 10.1128/Jvi.69.1.528-533.1995  0.618
1995 Battini JL, Danos O, Heard JM. Receptor-binding domain of murine leukemia virus envelope glycoproteins. Journal of Virology. 69: 713-9. PMID 7815534  0.506
1995 Salvetti A, Heard JM, Danos O. Gene therapy of lysosomal storage disorders. British Medical Bulletin. 51: 106-22. PMID 7767637  0.516
1995 Naffakh N, Henri A, Villeval JL, Rouyer-Fessard P, Moullier P, Blumenfeld N, Danos O, Vainchenker W, Heard JM, Beuzard Y. Sustained delivery of erythropoietin in mice by genetically modified skin fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 92: 3194-8. PMID 7724539  0.516
1995 Valere T, Bohl D, Klatzmann D, Danos O, Sonigo P, Heard JM. Continuous secretion of human soluble CD4 in mice transplanted with genetically modified cells. Gene Therapy. 2: 197-202. PMID 7614250  0.547
1995 Moullier P, Bohl D, Cardoso J, Heard JM, Danos O. Long-term delivery of a lysosomal enzyme by genetically modified fibroblasts in dogs. Nature Medicine. 1: 353-7. PMID 7585066 DOI: 10.1038/Nm0495-353  0.655
1995 Schwartz O, Maréchal V, Danos O, Heard JM. Human immunodeficiency virus type 1 Nef increases the efficiency of reverse transcription in the infected cell. Journal of Virology. 69: 4053-9. PMID 7539505 DOI: 10.1128/Jvi.69.7.4053-4059.1995  0.64
1995 Naffakh N, Moullier P, Salvetti A, Bohl D, Danos O, Heard JM. Delivery of therapeutic proteins from genetically-modified cells Restorative Neurology and Neuroscience. 8: 67-69.  0.495
1994 Valsesia-Wittmann S, Drynda A, Deléage G, Aumailley M, Heard JM, Danos O, Verdier G, Cosset FL. Modifications in the binding domain of avian retrovirus envelope protein to redirect the host range of retroviral vectors. Journal of Virology. 68: 4609-19. PMID 8207835 DOI: 10.1128/Jvi.68.7.4609-4619.1994  0.51
1994 Naffakh N, Bohl D, Salvetti A, Moullier P, Danos O, Heard JM. Gene therapy for lysosomal disorders. Nouvelle Revue FrançAise D'HéMatologie. 36: S11-6. PMID 8177709  0.556
1994 Battini JL, Kayman SC, Pinter A, Heard JM, Danos O. Role of N-linked glycosylation in the activity of the Friend murine leukemia virus SU protein receptor-binding domain. Virology. 202: 496-9. PMID 8009864 DOI: 10.1006/Viro.1994.1369  0.467
1994 Schwartz O, Alizon M, Heard JM, Danos O. Impairment of T cell receptor-dependent stimulation in CD4+ lymphocytes after contact with membrane-bound HIV-1 envelope glycoprotein. Virology. 198: 360-5. PMID 7903129 DOI: 10.1006/Viro.1994.1042  0.664
1993 Schwartz O, Rivière Y, Heard JM, Danos O. Reduced cell surface expression of processed human immunodeficiency virus type 1 envelope glycoprotein in the presence of Nef. Journal of Virology. 67: 3274-80. PMID 8497051 DOI: 10.1128/Jvi.67.6.3274-3280.1993  0.657
1993 Naffakh N, Le Gall S, Danos O, Heard JM, Cournot G, Motoyoshi K, Vilmer E. Macrophage colony-stimulating factor: serum levels and cDNA structure in malignant osteopetrosis. Blood. 81: 2817-8. PMID 8490189 DOI: 10.1182/Blood.V81.10.2817.2817  0.415
1993 Cardoso JE, Branchereau S, Jeyaraj PR, Houssin D, Danos O, Heard JM. In situ retrovirus-mediated gene transfer into dog liver. Human Gene Therapy. 4: 411-8. PMID 8399488 DOI: 10.1089/hum.1993.4.4-411  0.495
1993 Moullier P, Maréchal V, Danos O, Heard JM. Continuous systemic secretion of a lysosomal enzyme by genetically modified mouse skin fibroblasts. Transplantation. 56: 427-32. PMID 8356601 DOI: 10.1097/00007890-199308000-00034  0.674
1993 Maréchal V, Naffakh N, Danos O, Heard JM. Disappearance of lysosomal storage in spleen and liver of mucopolysaccharidosis VII mice after transplantation of genetically modified bone marrow cells. Blood. 82: 1358-65. PMID 8353294 DOI: 10.1182/Blood.V82.4.1358.Bloodjournal8241358  0.529
1993 Moullier P, Bohl D, Heard JM, Danos O. Correction of lysosomal storage in the liver and spleen of MPS VII mice by implantation of genetically modified skin fibroblasts. Nature Genetics. 4: 154-9. PMID 8348154 DOI: 10.1038/Ng0693-154  0.68
1993 Naffakh N, Pinset C, Montarras D, Pastoret C, Danos O, Heard JM. Transplantation of adult-derived myoblasts in mice following gene transfer. Neuromuscular Disorders : Nmd. 3: 413-7. PMID 8186684 DOI: 10.1016/0960-8966(93)90087-Z  0.506
1993 Houssin D, Danos O, Heard JM. [The liver and gene therapy. Experimental or revolutionary procedure?]. La Revue Du Praticien. 43: 2380-2. PMID 8128159  0.476
1993 Branchereau S, Ferry N, Myara A, Sato H, Kowai O, Trivin F, Houssin D, Danos O, Heard J. Correction of bilirubin glucuronyl transferase in Gunn rats by gene transfer in the liver using retroviral vectors | Correction du déficit en bilirubine glucuronyl-transférase chez le rat Gunn par transfert de gène dans le foie au moyen de vecteurs rétroviraux Chirurgie Paris. 119: 642-648. PMID 7729182  0.495
1993 Branchereau S, Ferry N, Myara A, Sato H, Kowai O, Trivin F, Houssin D, Danos O, Heard J. Correction of bilirubin glucuronyl transferase deficiency in the Guinn rat with gene transfer into the liver via retrovirus vectors | CORRECTION DU DEFICIT EN BILIRUBINE GLUCURONYL-TRANSFERASE CHEZ LE RAT GUNN PAR TRANSFERT DE GENE DANS LE FOIE AU MOYEN DE VECTEURS RETROVIRAUX Chirurgie - Memoires De L'Academie De Chirurgie. 119: 642-648.  0.475
1993 Danos O, Heard JM. Strategies and models for gene therapy | STRATEGIES ET MODELES POUR LA THERAPIE GENIQUE Annales De L'Institut Pasteur/Actualites. 4: 89-99.  0.464
1992 Schwartz O, Arenzana-Seisdedos F, Heard JM, Danos O. Activation pathways and human immunodeficiency virus type 1 replication are not altered in CD4+ T cells expressing the nef protein. Aids Research and Human Retroviruses. 8: 545-51. PMID 1355346 DOI: 10.1089/Aid.1992.8.545  0.641
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