Cesar de la Fuente-Nunez, Ph.D. - Publications

Bioengineering, Microbiology, Psychiatry University of Pennsylvania, Philadelphia, PA, United States 
Peptide design and engineering, synthetic biology, microbiology, computational biology

28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Palmer N, Maasch JRMA, Torres MDT, de la Fuente-Nunez C. Molecular dynamics for antimicrobial peptide discovery. Infection and Immunity. PMID 33558318 DOI: 10.1128/IAI.00703-20  0.36
2020 Silva ON, Torres MDT, Cao J, Alves ESF, Rodrigues LV, Resende JM, Lião LM, Porto WF, Fensterseifer ICM, Lu TK, Franco OL, de la Fuente-Nunez C. Repurposing a peptide toxin from wasp venom into antiinfectives with dual antimicrobial and immunomodulatory properties. Proceedings of the National Academy of Sciences of the United States of America. PMID 33046640 DOI: 10.1073/pnas.2012379117  1
2020 Torres MDT, Silva AF, Andrade GP, Pedron CN, Cerchiaro G, Ribeiro AO, Oliveira VX, de la Fuente-Nunez C. The wasp venom antimicrobial peptide polybia-CP and its synthetic derivatives display antiplasmodial and anticancer properties. Bioengineering & Translational Medicine. 5: e10167. PMID 33005737 DOI: 10.1002/btm2.10167  0.36
2019 Inda ME, Broset E, Lu TK, de la Fuente-Nunez C. Emerging Frontiers in Microbiome Engineering. Trends in Immunology. PMID 31601521 DOI: 10.1016/j.it.2019.08.007  1
2019 Agbale CM, Sarfo JK, Galyuon IK, Juliano SA, Silva GGO, Buccini DF, Cardoso MH, Torres MDT, Angeles-Boza AM, de la Fuente-Nunez C, Franco OL. Antimicrobial and Antibiofilm Activities of Helical Antimicrobial Peptide Sequences Incorporating Metal-Binding Motifs. Biochemistry. PMID 31448597 DOI: 10.1021/acs.biochem.9b00440  1
2019 Oshiro KGN, Cândido ES, Chan LY, Torres MT, Monges BED, Rodrigues SG, Porto WF, Ribeiro SM, Troeira Henriques S, Lu TK, de la Fuente-Nunez C, Craik DJ, Franco OL, Cardoso MH. Computer-aided design of mastoparan-like peptides enables the generation of non-toxic variants with extended antibacterial properties. Journal of Medicinal Chemistry. PMID 31411881 DOI: 10.1021/acs.jmedchem.9b00915  1
2019 Cândido ES, Cardoso MH, Chan LY, Torres MT, Oshiro K, Porto WF, Ribeiro SM, Haney EF, Hancock REW, Lu TK, de la Fuente-Nunez C, Craik DJ, Franco OL. A short cationic peptide derived from Archaea with dual antibacterial properties and anti-infective potential. Acs Infectious Diseases. PMID 31016969 DOI: 10.1021/acsinfecdis.9b00073  1
2019 Fensterseifer ICM, Felício MR, Alves ESF, Cardoso MH, Torres MDT, Matos CO, Silva ON, Lu TK, Freire MV, Neves NC, Gonçalves S, Lião LM, Santos NC, Porto WF, de la Fuente-Nunez C, et al. Selective antibacterial activity of the cationic peptide PaDBS1R6 against Gram-negative bacteria. Biochimica Et Biophysica Acta. Biomembranes. PMID 30926365 DOI: 10.1016/j.bbamem.2019.03.016  1
2019 Torres MDT, Sothiselvam S, Lu TK, de la Fuente-Nunez C. Peptide Design Principles for Antimicrobial Applications. Journal of Molecular Biology. PMID 30611750 DOI: 10.1016/j.jmb.2018.12.015  1
2018 Fleitas Martínez O, Rigueiras PO, Pires ÁDS, Porto WF, Silva ON, de la Fuente-Nunez C, Franco OL. Interference With Quorum-Sensing Signal Biosynthesis as a Promising Therapeutic Strategy Against Multidrug-Resistant Pathogens. Frontiers in Cellular and Infection Microbiology. 8: 444. PMID 30805311 DOI: 10.3389/fcimb.2018.00444  1
2018 Torres MDT, Pedron CN, Higashikuni Y, Kramer RM, Cardoso MH, Oshiro KGN, Franco OL, Silva Junior PI, Silva FD, Oliveira Junior VX, Lu TK, de la Fuente-Nunez C. Structure-function-guided exploration of the antimicrobial peptide polybia-CP identifies activity determinants and generates synthetic therapeutic candidates. Communications Biology. 1: 221. PMID 30534613 DOI: 10.1038/s42003-018-0224-2  1
2018 Cardoso M, Cândido E, Chan L, Torres MT, Oshiro K, Rezende S, Porto WF, Lu TK, de la Fuente-Nunez C, Craik DJ, Franco OL. A computationally designed peptide derived from Escherichia colias a potential drug template for antibacterial and antibiofilm therapies. Acs Infectious Diseases. PMID 30346140 DOI: 10.1021/acsinfecdis.8b00219  1
2018 Pane K, Cafaro V, Avitabile A, Torres MT, Vollaro A, De Gregorio E, Catania MR, Di Maro A, Bosso A, Gallo G, Zanfardino A, Varcamonti M, Pizzo E, Di Donato A, Lu TK, ... de la Fuente-Nunez C, et al. Identification of Novel Cryptic Multifunctional Antimicrobial Peptides from the Human Stomach Enabled by a Computational-Experimental Platform. Acs Synthetic Biology. PMID 30124040 DOI: 10.1021/acssynbio.8b00084  1
2018 Torres MDT, Andrade GP, Sato RH, Pedron CN, Manieri TM, Cerchiaro G, Ribeiro AO, de la Fuente-Nunez C, Oliveira VX. Natural and redesigned wasp venom peptides with selective antitumoral activity. Beilstein Journal of Organic Chemistry. 14: 1693-1703. PMID 30013694 DOI: 10.3762/bjoc.14.144  0.36
2018 Pizzo E, Pane K, Bosso A, Landi N, Ragucci S, Russo R, Gaglione R, Torres MDT, de la Fuente-Nunez C, Arciello A, Di Donato A, Notomista E, Di Maro A. Novel bioactive peptides from PD-L1/2, a type 1 ribosome inactivating protein from Phytolacca dioica L. Evaluation of their antimicrobial properties and anti-biofilm activities. Biochimica Et Biophysica Acta. PMID 29684330 DOI: 10.1016/j.bbamem.2018.04.010  0.36
2018 Porto WF, Irazazabal L, Alves ESF, Ribeiro SM, Matos CO, Pires ÁS, Fensterseifer ICM, Miranda VJ, Haney EF, Humblot V, Torres MDT, Hancock REW, Liao LM, Ladram A, Lu TK, ... de la Fuente-Nunez C, et al. In silico optimization of a guava antimicrobial peptide enables combinatorial exploration for peptide design. Nature Communications. 9: 1490. PMID 29662055 DOI: 10.1038/s41467-018-03746-3  1
2018 Cao J, de la Fuente-Nunez C, Ou RW, Torres MD, Pande SG, Sinskey AJ, Lu TK. Yeast-based synthetic biology platform for antimicrobial peptide production. Acs Synthetic Biology. PMID 29366323 DOI: 10.1021/acssynbio.7b00396  1
2018 Cao J, Perez-Pinera P, Lowenhaupt K, Wu MR, Purcell O, de la Fuente-Nunez C, Lu TK. Versatile and on-demand biologics co-production in yeast. Nature Communications. 9: 77. PMID 29311542 DOI: 10.1038/s41467-017-02587-w  1
2017 de la Fuente-Nunez C, Meneguetti BT, Franco OL, Lu TK. Neuromicrobiology: How Microbes Influence the Brain. Acs Chemical Neuroscience. PMID 29220570 DOI: 10.1021/acschemneuro.7b00373  0.92
2017 Liu X, Yuk H, Lin S, Parada GA, Tang TC, Tham E, de la Fuente-Nunez C, Lu TK, Zhao X. 3D Printing of Living Responsive Materials and Devices. Advanced Materials (Deerfield Beach, Fla.). PMID 29205532 DOI: 10.1002/adma.201704821  1
2017 Verderosa AD, de la Fuente-Núñez C, Mansour SC, Cao J, Lu TK, Hancock REW, Fairfull-Smith KE. Ciprofloxacin-nitroxide hybrids with potential for biofilm control. European Journal of Medicinal Chemistry. 138: 590-601. PMID 28709125 DOI: 10.1016/j.ejmech.2017.06.058  1
2017 de la Fuente-Nunez C, Torres MD, Mojica FJ, Lu TK. Next-generation precision antimicrobials: towards personalized treatment of infectious diseases. Current Opinion in Microbiology. 37: 95-102. PMID 28623720 DOI: 10.1016/j.mib.2017.05.014  1
2017 Freitas CG, Lima SMF, Freire MS, Cantuária APC, Júnior NGO, Santos TS, Folha JS, Ribeiro SM, Dias SC, Rezende TMB, Albuquerque P, Nicola AM, de la Fuente-Núñez C, Hancock REW, Franco OL, et al. An immunomodulatory peptide that confers protection in an experimental candidemia murine model. Antimicrobial Agents and Chemotherapy. PMID 28559266 DOI: 10.1128/AAC.02518-16  1
2017 de la Fuente-Núñez C, Silva ON, Lu TK, Franco OL. Antimicrobial Peptides: Role in Human Disease and Potential as Immunotherapies. Pharmacology & Therapeutics. PMID 28435091 DOI: 10.1016/j.pharmthera.2017.04.002  1
2017 de la Fuente-Núñez C, Lu TK. CRISPR-Cas9 technology: applications in genome engineering, development of sequence-specific antimicrobials, and future prospects. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 28045163 DOI: 10.1039/c6ib00140h  1
2016 da Cunha NB, Cobacho NB, Viana JF, Lima LA, Sampaio KB, Dohms SS, Ferreira AC, de la Fuente-Núñez C, Costa FF, Franco OL, Dias SC. The next generation of antimicrobial peptides (AMPs) as molecular therapeutic tools for the treatment of diseases with social and economic impacts. Drug Discovery Today. PMID 27890668 DOI: 10.1016/j.drudis.2016.10.017  1
2016 Silva ON, de la Fuente-Núñez C, Haney EF, Fensterseifer IC, Ribeiro SM, Porto WF, Brown P, Faria-Junior C, Rezende TM, Moreno SE, Lu TK, Hancock RE, Franco OL. An anti-infective synthetic peptide with dual antimicrobial and immunomodulatory activities. Scientific Reports. 6: 35465. PMID 27804992 DOI: 10.1038/srep35465  1
2016 Cardoso MH, Ribeiro SM, Nolasco DO, de la Fuente-Núñez C, Felício MR, Gonçalves S, Matos CO, Liao LM, Santos NC, Hancock RE, Franco OL, Migliolo L. A polyalanine peptide derived from polar fish with anti-infectious activities. Scientific Reports. 6: 21385. PMID 26916401 DOI: 10.1038/srep21385  1
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