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Robert A. Blouin - Publications

Affiliations: 
1978-2003 Pharmacy University of Kentucky, Lexington, KY 
 2003- University of North Carolina, Chapel Hill, Chapel Hill, NC 
Website:
https://pharmacy.unc.edu/news/2017/08/22/dean-bob-blouin-succeed-jim-dean-university-north-carolina-chapel-hill-provost/
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42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2002 Van Ess PJ, Poloyac S, Mattson MP, Blouin RA. Blunted induction of hepatic CYP4A in TNF (p55-/-/p75-/-) double receptor knockout mice following clofibrate treatment. Pharmaceutical Research. 19: 708-12. PMID 12069177 DOI: 10.1023/A:1015326717522  0.705
2002 Van Ess PJ, Mattson MP, Blouin RA. Enhanced induction of cytochrome P450 enzymes and CAR binding in TNF (p55(-/-)/p75(-/-)) double receptor knockout mice following phenobarbital treatment. The Journal of Pharmacology and Experimental Therapeutics. 300: 824-30. PMID 11861787 DOI: 10.1124/Jpet.300.3.824  0.716
2002 Van Ess PJ, Pedersen WA, Culmsee C, Mattson MP, Blouin RA. Elevated hepatic and depressed renal cytochrome P450 activity in the Tg2576 transgenic mouse model of Alzheimer's disease. Journal of Neurochemistry. 80: 571-8. PMID 11841564 DOI: 10.1046/J.0022-3042.2001.00724.X  0.352
2001 Warren GW, Van Ess PJ, Watson AM, Mattson MP, Blouin RA. Cytochrome P450 and antioxidant activity in interleukin-6 knockout mice after induction of the acute-phase response Journal of Interferon and Cytokine Research. 21: 821-826. PMID 11710994 DOI: 10.1089/107999001753238060  0.326
2001 Roe AL, Poloyac SM, Howard G, Shedlofsky SI, Blouin RA. The effect of endotoxin on hepatocyte nuclear factor 1 nuclear protein binding: potential implications on CYP2E1 expression in the rat. The Journal of Pharmacy and Pharmacology. 53: 1365-71. PMID 11697544 DOI: 10.1211/0022357011777864  0.322
2001 Oakley GG, Roe AL, Blouin RA, Twaroski TP, Ganguly TC, Vore M, Robertson HJLLW. 2,4,4′-Trichlorobiphenyl increases STAT5 transcriptional activity Molecular Carcinogenesis. 30: 199-208. PMID 11346882 DOI: 10.1002/Mc.1029  0.56
1999 Poloyac SM, Tosheva RT, Gardner BM, Shedlofsky SI, Blouin RA. The effect of endotoxin administration on the pharmacokinetics of chlorzoxazone in humans. Clinical Pharmacology and Therapeutics. 66: 554-62. PMID 10613610 DOI: 10.1053/Cp.1999.V66.103172001  0.344
1999 Lu M, Poloyac SM, Mcnamara PJ, Blouin RA. The Effect of Pregnenolone 16α‐Carbonitrile on the Pharmacokinetics and Metabolism of Dapsone in Rats Journal of Pharmacy and Pharmacology. 51: 803-810. PMID 10467955 DOI: 10.1211/0022357991773177  0.336
1999 Roe AL, Howard G, Blouin R, Snawder JE. Characterization of cytochrome P450 and glutathione S-transferase activity and expression in male and female ob/ob mice. International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association For the Study of Obesity. 23: 48-53. PMID 10094576 DOI: 10.1038/Sj.Ijo.0800756  0.346
1999 Watson AM, Warren G, Howard G, Shedlofsky SI, Blouin RA. Activities of conjugating and antioxidant enzymes following endmost exposure Journal of Biochemical and Molecular Toxicology. 13: 63-69. PMID 9890190 DOI: 10.1002/(Sici)1099-0461(1999)13:2<63::Aid-Jbt1>3.0.Co;2-I  0.31
1998 Roe AL, Howard G, Blouin RA. Characterization of nuclear protein binding (AP-1, GR, and STAT) in the genetically obese (fa/fa) Zucker rat. Life Sciences. 63: 1339-46. PMID 9768871 DOI: 10.1016/S0024-3205(98)00397-X  0.314
1997 Shedlofsky SI, Israel BC, Tosheva R, Blouin R. Endotoxin depresses hepatic cytochrome P450-mediated drug metabolism in women British Journal of Clinical Pharmacology. 43: 627-632. PMID 9205823 DOI: 10.1046/J.1365-2125.1997.00603.X  0.341
1996 Roe AL, Blouin RA, Howard G. In vivo phenobarbital treatment increases protein binding to a putative AP-1 site in the CYP2B2 promoter. Biochemical and Biophysical Research Communications. 228: 110-4. PMID 8912644 DOI: 10.1006/Bbrc.1996.1624  0.308
1994 Bandyopadhyay AM, Chaudhary I, Robertson LW, Gemzik B, Parkinson A, Blouin RA. Expression of a male-specific cytochrome P450 isozyme (CYP2C11) in fa/fa Zucker rats: effect of phenobarbital treatment. Archives of Biochemistry and Biophysics. 307: 386-90. PMID 8274026 DOI: 10.1006/Abbi.1993.1604  0.339
1994 Tuntaterdtum S, Chaudhary IP, Cibull M, Robertson LW, Blouin RA. Acetaminophen hepatotoxicity: influence of phenobarbital and beta-naphthoflavone treatment in obese and lean Zucker rats. Toxicology and Applied Pharmacology. 123: 219-25. PMID 8248929 DOI: 10.1006/Taap.1993.1240  0.36
1994 Shedlofsky SI, Israel BC, McClain CJ, Hill DB, Blouin RA. Endotoxin administration to humans inhibits hepatic cytochrome P450-mediated drug metabolism Journal of Clinical Investigation. 94: 2209-2214. PMID 7989576 DOI: 10.1172/Jci117582  0.353
1993 Israel B, Blouin R, McIntyre W, Shedlofsky S. Effects of interferon-alpha monotherapy on hepatic drug metabolism in cancer patients. British Journal of Clinical Pharmacology. 36: 229-235. PMID 9114909 DOI: 10.1111/J.1365-2125.1993.Tb04222.X  0.301
1993 Blouin RA, Bandyopadhyay AM, Chaudhary I, Robertson LW, Gemzik B, Parkinson A. Cytochrome P450 2B enzyme (CYP2B) induction defect following phenobarbital treatment in the fa/fa Zucker rat: molecular characterization. Archives of Biochemistry and Biophysics. 303: 313-20. PMID 8512318 DOI: 10.1006/Abbi.1993.1289  0.314
1992 Blouin RA, Hamelin BA, Smith DA, Foster TS, John WJ, Welker HA. Fleroxacin pharmacokinetics in patients with liver cirrhosis Antimicrobial Agents and Chemotherapy. 36: 632-638. PMID 1622175 DOI: 10.1128/Aac.36.3.632  0.352
1992 Colangelo PM, Blouin RA, Steinmetz JE, McNamara PJ, DeMaria AN, Wedlund PJ. Age and propranolol stereoselective disposition in humans. Clinical Pharmacology and Therapeutics. 51: 489-94. PMID 1587061 DOI: 10.1038/Clpt.1992.52  0.309
1991 Smith DA, Chandler MHH, Shedlofsky SI, Wedlund PJ, Blouin RA. Age-dependent stereoselective increase in the oral clearance of hexobarbitone isomers caused by rifampicin. British Journal of Clinical Pharmacology. 32: 735-739. DOI: 10.1111/J.1365-2125.1991.Tb03982.X  0.308
1990 Chandler MHH, Clifton GD, Burki NK, Hunt BA, Blouin RA. Pulmonary function in the elderly: Response to theophylline bronchodilation The Journal of Clinical Pharmacology. 30: 330-335. PMID 2341580 DOI: 10.1002/J.1552-4604.1990.Tb03602.X  0.3
1990 McNamara PJ, Blouin RA. Pharmacokinetic profile of two aromatic retinoids (etretinate and acitretin) in the obese Zucker rat. Journal of Pharmaceutical Sciences. 79: 301-304. PMID 2141075 DOI: 10.1002/Jps.2600790406  0.319
1990 Blouin RA, Kneer J, Ambros RJ, Stoeckel K. Influence of antacid and ranitidine on the pharmacokinetics of oral cefetamet pivoxil. Antimicrobial Agents and Chemotherapy. 34: 1744-1748. PMID 1981000 DOI: 10.1128/Aac.34.9.1744  0.332
1989 Blouin RA, Kneer J, Stoeckel K. Pharmacokinetics of intravenous cefetamet (Ro 15-8074) and oral cefetamet pivoxil (Ro 15-8075) in young and elderly subjects. Antimicrobial Agents and Chemotherapy. 33: 291-296. PMID 2729925 DOI: 10.1128/Aac.33.3.291  0.326
1989 Colangelo P, Chandler M, Blouin R, McNamara P. Stereoselective binding of propranolol in the elderly British Journal of Clinical Pharmacology. 27: 519-522. PMID 2719906 DOI: 10.1111/J.1365-2125.1989.Tb05402.X  0.301
1989 Kneer J, Tam YK, Blouin RA, Frey FJ, Keller E, Stathakis C, Luginbuehl B, Stoeckel K. Pharmacokinetics of intravenous cefetamet and oral cefetamet pivoxil in patients with renal insufficiency. Antimicrobial Agents and Chemotherapy. 33: 1952-1957. PMID 2610506 DOI: 10.1128/Aac.33.11.1952  0.333
1989 Hatton J, Parr MD, Blouin RA. Estimation of creatinine clearance in patients with Cushing's syndrome. Dicp-the Annals of Pharmacotherapy. 23: 974-977. PMID 2603451 DOI: 10.1177/106002808902301203  0.309
1988 Chandler MHH, Scott SR, Blouin RA. Age‐associated stereoselective alterations in hexobarbital metabolism Clinical Pharmacology & Therapeutics. 43: 436-441. PMID 3356087 DOI: 10.1038/Clpt.1988.55  0.356
1988 McNamara PJ, Blouin RA, Brazzell RK. The protein binding of phenytoin, propranolol, diazepam, and AL01576 (an aldose reductase inhibitor) in human and rat diabetic serum. Pharmaceutical Research. 5: 261-265. PMID 3149736 DOI: 10.1023/A:1015966402084  0.308
1988 Chandler MHH, Schran HF, Cutler RE, Smith AJ, Gonasun LM, Blouin RA. The effects of renal function on the disposition of isradipine. The Journal of Clinical Pharmacology. 28: 1076-1080. PMID 2977394 DOI: 10.1002/J.1552-4604.1988.Tb05717.X  0.312
1985 Wermeling D, Record K, Bell R, Porter W, Blouin R. Hemodialysis clearance of pentobarbital during continuous infusion. Therapeutic Drug Monitoring. 7: 485-487. PMID 4082247 DOI: 10.1097/00007691-198512000-00023  0.307
1985 Benedek IH, Blouin R, McNamara PJ. Altered Drug–Serum Protein Binding in the Genetically Obese Zucker Rat Journal of Pharmaceutical Sciences. 74: 837-840. PMID 4032266 DOI: 10.1002/Jps.2600740807  0.305
1985 Hamann SR, Tan TG, Kaltenborn KE, Brouwer KL, Blouin RA, Chang SL, Vore M, McAllister RG. Effects of phenobarbital and SKF-525A on in vitro hepatic metabolism of verapamil and nifedipine. Pharmacology. 30: 121-8. PMID 3975261 DOI: 10.1159/000138060  0.584
1984 Benedek I, Blouin R, McNamara P. Serum protein binding and the role of increased alpha 1‐acid glycoprotein in moderately obese male subjects British Journal of Clinical Pharmacology. 18: 941-946. PMID 6529534 DOI: 10.1111/J.1365-2125.1984.Tb02567.X  0.307
1984 Brouwer KL, Kostenbauder HB, McNamara PJ, Blouin RA. Phenobarbital in the genetically obese Zucker rat. II. In vivo and in vitro assessments of microsomal enzyme induction Journal of Pharmacology and Experimental Therapeutics. 231: 654-659. PMID 6502519  0.612
1984 Brouwer KL, Kostenbauder HB, McNamara PJ, Blouin RA. Phenobarbital in the genetically obese Zucker rat. I. Pharmacokinetics after acute and chronic administration. The Journal of Pharmacology and Experimental Therapeutics. 231: 649-53. PMID 6502518  0.59
1983 Benedek I, Griffen W, Bell R, Blouin R, McNamara P. Serum alpha 1-acid glycoprotein and the binding of drugs in obesity. British Journal of Clinical Pharmacology. 16: 751-754. PMID 6661365 DOI: 10.1111/J.1365-2125.1983.Tb02258.X  0.311
1982 Blouin RA, Bauer LA, Miller DD, Record KE, Griffen WO. Vancomycin pharmacokinetics in normal and morbidly obese subjects. Antimicrobial Agents and Chemotherapy. 21: 575-80. PMID 7081978 DOI: 10.1128/Aac.21.4.575  0.301
1982 Bauer LA, Blouin RA. Age and phenytoin kinetics in adult epileptics. Clinical Pharmacology and Therapeutics. 31: 301-4. PMID 7060313 DOI: 10.1038/Clpt.1982.37  0.33
1981 Lawson LA, Blouin RA, Smith RB, Rapp RP, Young AB. Phenytoin-dexamethasone interaction: a previously unreported observation. Surgical Neurology. 16: 23-4. PMID 7280966 DOI: 10.1016/S0090-3019(81)80054-7  0.321
1980 Blouin RA, Erwin GW, Dutro MP, Bustrack JA, Rowse KL. Chloramphenicol hemodialysis clearance. Therapeutic Drug Monitoring. 2: 351-354. DOI: 10.1097/00007691-198002040-00007  0.301
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