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Alissa C Rothchild, Ph.D. - Publications

Affiliations: 
2020- University of Massachusetts, Amherst, Amherst, MA 
Area:
immunology, tuberculosis
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Mai D, Jahn A, Murray T, Morikubo M, Lim PN, Cervantes MM, Pham LK, Nemeth J, Urdahl K, Diercks AH, Aderem A, Rothchild AC. Exposure to Mycobacterium remodels alveolar macrophages and the early innate response to Mycobacterium tuberculosis infection. Plos Pathogens. 20: e1011871. PMID 38236787 DOI: 10.1371/journal.ppat.1011871  0.724
2021 Lim PN, Cervantes MM, Pham LK, Rothchild AC. Alveolar macrophages: novel therapeutic targets for respiratory diseases. Expert Reviews in Molecular Medicine. 23: e18. PMID 34823627 DOI: 10.1017/erm.2021.21  0.698
2021 Duffy FJ, Olson GS, Gold ES, Jahn A, Aderem A, Aitchison J, Rothchild AC, Diercks AH, Nemeth J. A contained Mycobacterium tuberculosis mouse infection model predicts active disease and containment in humans. The Journal of Infectious Diseases. PMID 33693706 DOI: 10.1093/infdis/jiab130  0.604
2020 Su Y, Chen D, Yuan D, Lausted C, Choi J, Dai CL, Voillet V, Duvvuri VR, Scherler K, Troisch P, Baloni P, Qin G, Smith B, Kornilov SA, Rostomily C, ... ... Rothchild A, et al. Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19. Cell. PMID 33171100 DOI: 10.1016/j.cell.2020.10.037  0.588
2020 Rothchild AC, Mai D, Aderem A, Diercks AH. Flow Cytometry Analysis and Fluorescence-activated Cell Sorting of Myeloid Cells from Lung and Bronchoalveolar Lavage Samples from -infected Mice. Bio-Protocol. 10. PMID 32995363 DOI: 10.21769/bioprotoc.3630  0.68
2020 Su Y, Chen D, Lausted C, Yuan D, Choi J, Dai C, Voillet V, Scherler K, Troisch P, Duvvuri VR, Baloni P, Qin G, Smith B, Kornilov S, Rostomily C, ... ... Rothchild A, et al. Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection Trajectories. Biorxiv : the Preprint Server For Biology. PMID 32766585 DOI: 10.1101/2020.07.27.224063  0.68
2020 Nemeth J, Olson GS, Rothchild AC, Jahn AN, Mai D, Duffy FJ, Delahaye JL, Srivatsan S, Plumlee CR, Urdahl KB, Gold ES, Aderem A, Diercks AH. Contained Mycobacterium tuberculosis infection induces concomitant and heterologous protection. Plos Pathogens. 16: e1008655. PMID 32673357 DOI: 10.1371/Journal.Ppat.1008655  0.753
2020 Nemeth J, Olson GS, Rothchild AC, Jahn AN, Mai D, Duffy FJ, Delahaye JL, Srivatsan S, Plumlee CR, Urdahl KB, Gold ES, Aderem A, Diercks AH. Pathology scores for Mtb-infection of CMTB and control mice. Plos Pathogens. DOI: 10.1371/Journal.Ppat.1008655.S022  0.339
2020 Nemeth J, Olson GS, Rothchild AC, Jahn AN, Mai D, Duffy FJ, Delahaye JL, Srivatsan S, Plumlee CR, Urdahl KB, Gold ES, Aderem A, Diercks AH. Lung myeloid cell gating strategy. Plos Pathogens. DOI: 10.1371/Journal.Ppat.1008655.S019  0.343
2020 Nemeth J, Olson GS, Rothchild AC, Jahn AN, Mai D, Duffy FJ, Delahaye JL, Srivatsan S, Plumlee CR, Urdahl KB, Gold ES, Aderem A, Diercks AH. Splenic myeloid cell gating strategy. Plos Pathogens. DOI: 10.1371/Journal.Ppat.1008655.S018  0.355
2020 Nemeth J, Olson GS, Rothchild AC, Jahn AN, Mai D, Duffy FJ, Delahaye JL, Srivatsan S, Plumlee CR, Urdahl KB, Gold ES, Aderem A, Diercks AH. Peripheral blood monocyte gating strategy. Plos Pathogens. DOI: 10.1371/Journal.Ppat.1008655.S017  0.326
2020 Nemeth J, Olson GS, Rothchild AC, Jahn AN, Mai D, Duffy FJ, Delahaye JL, Srivatsan S, Plumlee CR, Urdahl KB, Gold ES, Aderem A, Diercks AH. Lung and peripheral blood T cell gating strategy. Plos Pathogens. DOI: 10.1371/Journal.Ppat.1008655.S016  0.402
2020 Nemeth J, Olson GS, Rothchild AC, Jahn AN, Mai D, Duffy FJ, Delahaye JL, Srivatsan S, Plumlee CR, Urdahl KB, Gold ES, Aderem A, Diercks AH. ATAC-seq on AM from naïve/infected mice at baseline. Plos Pathogens. DOI: 10.1371/Journal.Ppat.1008655.S015  0.312
2020 Nemeth J, Olson GS, Rothchild AC, Jahn AN, Mai D, Duffy FJ, Delahaye JL, Srivatsan S, Plumlee CR, Urdahl KB, Gold ES, Aderem A, Diercks AH. Distribution of Mtb infection across pulmonary immune cells. Plos Pathogens. DOI: 10.1371/Journal.Ppat.1008655.S013  0.431
2020 Nemeth J, Olson GS, Rothchild AC, Jahn AN, Mai D, Duffy FJ, Delahaye JL, Srivatsan S, Plumlee CR, Urdahl KB, Gold ES, Aderem A, Diercks AH. T cells from treated CMTB mice fail to expand upon infection. Plos Pathogens. DOI: 10.1371/Journal.Ppat.1008655.S011  0.423
2020 Nemeth J, Olson GS, Rothchild AC, Jahn AN, Mai D, Duffy FJ, Delahaye JL, Srivatsan S, Plumlee CR, Urdahl KB, Gold ES, Aderem A, Diercks AH. Protective efficacy of BCG Pasteur. Plos Pathogens. DOI: 10.1371/Journal.Ppat.1008655.S004  0.387
2020 Nemeth J, Olson GS, Rothchild AC, Jahn AN, Mai D, Duffy FJ, Delahaye JL, Srivatsan S, Plumlee CR, Urdahl KB, Gold ES, Aderem A, Diercks AH. Dissemination of Mtb to the spleen in the CMTB model. Plos Pathogens. DOI: 10.1371/Journal.Ppat.1008655.S001  0.329
2019 Rothchild AC, Olson GS, Nemeth J, Amon LM, Mai D, Gold ES, Diercks AH, Aderem A. Alveolar macrophages generate a noncanonical NRF2-driven transcriptional response in vivo. Science Immunology. 4. PMID 31350281 DOI: 10.1126/Sciimmunol.Aaw6693  0.712
2019 Peterson EJ, Bailo R, Rothchild AC, Arrieta-Ortiz ML, Kaur A, Pan M, Mai D, Abidi AA, Cooper C, Aderem A, Bhatt A, Baliga NS. Path-seq identifies an essential mycolate remodeling program for mycobacterial host adaptation. Molecular Systems Biology. 15: e8584. PMID 30833303 DOI: 10.15252/Msb.20188584  0.675
2017 Rothchild AC, Stowell B, Goyal G, Nunes-Alves C, Yang Q, Papavinasasundaram K, Sassetti CM, Dranoff G, Chen X, Lee J, Behar SM. Role of Granulocyte-Macrophage Colony-Stimulating Factor Production by T Cells during Mycobacterium tuberculosis Infection. Mbio. 8. PMID 29066547 DOI: 10.1128/Mbio.01514-17  0.816
2016 Rothchild AC, Sissons JR, Shafiani S, Plaisier C, Min D, Mai D, Gilchrist M, Peschon J, Larson RP, Bergthaler A, Baliga NS, Urdahl KB, Aderem A. MiR-155-regulated molecular network orchestrates cell fate in the innate and adaptive immune response to Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 27681624 DOI: 10.1073/Pnas.1608255113  0.634
2015 Nunes-Alves C, Booty MG, Carpenter SM, Rothchild AC, Martin CJ, Desjardins D, Steblenko K, Kløverpris HN, Madansein R, Ramsuran D, Leslie A, Correia-Neves M, Behar SM. Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR Selection. Plos Pathogens. 11: e1004849. PMID 25945999 DOI: 10.1371/Journal.Ppat.1004849  0.764
2014 Nunes-Alves C, Booty MG, Carpenter SM, Jayaraman P, Rothchild AC, Behar SM. In search of a new paradigm for protective immunity to TB. Nature Reviews. Microbiology. 12: 289-99. PMID 24590243 DOI: 10.1038/Nrmicro3230  0.741
2014 Rothchild AC, Jayaraman P, Nunes-Alves C, Behar SM. iNKT cell production of GM-CSF controls Mycobacterium tuberculosis. Plos Pathogens. 10: e1003805. PMID 24391492 DOI: 10.1371/Journal.Ppat.1003805  0.801
2013 Zhang YJ, Reddy MC, Ioerger TR, Rothchild AC, Dartois V, Schuster BM, Trauner A, Wallis D, Galaviz S, Huttenhower C, Sacchettini JC, Behar SM, Rubin EJ. Tryptophan biosynthesis protects mycobacteria from CD4 T-cell-mediated killing. Cell. 155: 1296-308. PMID 24315099 DOI: 10.1016/J.Cell.2013.10.045  0.764
2013 Tatituri RV, Watts GF, Bhowruth V, Barton N, Rothchild A, Hsu FF, Almeida CF, Cox LR, Eggeling L, Cardell S, Rossjohn J, Godfrey DI, Behar SM, Besra GS, Brenner MB, et al. Recognition of microbial and mammalian phospholipid antigens by NKT cells with diverse TCRs. Proceedings of the National Academy of Sciences of the United States of America. 110: 1827-32. PMID 23307809 DOI: 10.1073/Pnas.1220601110  0.775
2011 Sillé FC, Martin C, Jayaraman P, Rothchild A, Fortune S, Besra GS, Behar SM, Boes M. Requirement for invariant chain in macrophages for Mycobacterium tuberculosis replication and CD1d antigen presentation. Infection and Immunity. 79: 3053-63. PMID 21576321 DOI: 10.1128/Iai.01108-10  0.793
2011 Sillé FC, Martin C, Jayaraman P, Rothchild A, Besra GS, Behar SM, Boes M. Critical role for invariant chain in CD1d-mediated selection and maturation of Vα14-invariant NKT cells. Immunology Letters. 139: 33-41. PMID 21565221 DOI: 10.1016/J.Imlet.2011.04.012  0.767
2010 Garces A, Atmakuri K, Chase MR, Woodworth JS, Krastins B, Rothchild AC, Ramsdell TL, Lopez MF, Behar SM, Sarracino DA, Fortune SM. EspA acts as a critical mediator of ESX1-dependent virulence in Mycobacterium tuberculosis by affecting bacterial cell wall integrity. Plos Pathogens. 6: e1000957. PMID 20585630 DOI: 10.1371/Journal.Ppat.1000957  0.788
2009 Chen H, Piechocka-Trocha A, Miura T, Brockman MA, Julg BD, Baker BM, Rothchild AC, Block BL, Schneidewind A, Koibuchi T, Pereyra F, Allen TM, Walker BD. Differential neutralization of human immunodeficiency virus (HIV) replication in autologous CD4 T cells by HIV-specific cytotoxic T lymphocytes. Journal of Virology. 83: 3138-49. PMID 19158248 DOI: 10.1128/Jvi.02073-08  0.414
2009 Miura T, Brockman MA, Schneidewind A, Lobritz M, Pereyra F, Rathod A, Block BL, Brumme ZL, Brumme CJ, Baker B, Rothchild AC, Li B, Trocha A, Cutrell E, Frahm N, et al. HLA-B57/B*5801 human immunodeficiency virus type 1 elite controllers select for rare gag variants associated with reduced viral replication capacity and strong cytotoxic T-lymphocyte [corrected] recognition. Journal of Virology. 83: 2743-55. PMID 19116253 DOI: 10.1128/Jvi.02265-08  0.317
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