Mark Alan Sussman - Publications

Affiliations: 
1995-2003 Molecular Cardiovascular Biology University of Cincinnati College of Medicine, Cincinnati, OH, United States 
 2003- Biology California State University, Los Angeles, CA, United States 
Area:
myocardial research
Website:
http://heart.sdsu.edu/lab/meet-dr-sussman/

114 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Samse K, Hariharan N, Sussman MA. Personalizing cardiac regenerative therapy: at the heart of Pim1 kinase. Pharmacological Research. PMID 26563999 DOI: 10.1016/J.Phrs.2015.11.001  1
2015 Quijada P, Salunga HT, Hariharan N, Cubillo J, El-Sayed F, Moshref M, Bala KM, Emathinger JM, De La Torre A, Ormachea L, Alvarez R, Gude NA, Sussman MA. Cardiac Stem Cell Hybrids Enhance Myocardial Repair. Circulation Research. PMID 26228030 DOI: 10.1161/Circresaha.115.306838  1
2015 Monsanto M, Sussman MA. Myocardial Infarct Scar: Hunting Down the Responsible Cells, But Then What? Journal of the American College of Cardiology. 65: 2067-9. PMID 25975468 DOI: 10.1016/J.Jacc.2015.03.519  1
2015 Gude N, Joyo E, Toko H, Quijada P, Villanueva M, Hariharan N, Sacchi V, Truffa S, Joyo A, Voelkers M, Alvarez R, Sussman MA. Notch activation enhances lineage commitment and protective signaling in cardiac progenitor cells. Basic Research in Cardiology. 110: 29. PMID 25893875 DOI: 10.1007/S00395-015-0488-3  1
2015 Hariharan N, Sussman MA. Cardiac aging - Getting to the stem of the problem. Journal of Molecular and Cellular Cardiology. 83: 32-6. PMID 25886698 DOI: 10.1016/J.Yjmcc.2015.04.008  1
2015 Nguyen N, Sussman MA. Rejuvenating the senescent heart. Current Opinion in Cardiology. 30: 235-9. PMID 25760821 DOI: 10.1097/Hco.0000000000000161  1
2015 Quijada P, Sussman MA. Circulating around the tissue: hematopoietic cell-based fusion versus transdifferentiation. Circulation Research. 116: 563-5. PMID 25677514 DOI: 10.1161/Circresaha.115.305820  1
2015 Hariharan N, Quijada P, Mohsin S, Joyo A, Samse K, Monsanto M, De La Torre A, Avitabile D, Ormachea L, McGregor MJ, Tsai EJ, Sussman MA. Nucleostemin rejuvenates cardiac progenitor cells and antagonizes myocardial aging. Journal of the American College of Cardiology. 65: 133-47. PMID 25593054 DOI: 10.1016/J.Jacc.2014.09.086  1
2015 Awad S, Al-Haffar KM, Marashly Q, Quijada P, Kunhi M, Al-Yacoub N, Wade FS, Mohammed SF, Al-Dayel F, Sutherland G, Assiri A, Sussman M, Bers D, Al-Habeeb W, Poizat C. Control of histone H3 phosphorylation by CaMKIIδ in response to haemodynamic cardiac stress. The Journal of Pathology. 235: 606-18. PMID 25421395 DOI: 10.1002/Path.4489  1
2014 Siddiqi S, Sussman MA. The heart: mostly postmitotic or mostly premitotic? Myocyte cell cycle, senescence, and quiescence. The Canadian Journal of Cardiology. 30: 1270-8. PMID 25442430 DOI: 10.1016/J.Cjca.2014.08.014  1
2014 Sussman MA, Puceat M. Response to letter regarding article, "Embryonic stem cell-derived cardiac myocytes are not ready for human trials". Circulation Research. 115: e30-1. PMID 25342772 DOI: 10.1161/Circresaha.114.305341  1
2014 Quijada P, Sussman MA. Making it stick: chasing the optimal stem cells for cardiac regeneration. Expert Review of Cardiovascular Therapy. 12: 1275-88. PMID 25340282 DOI: 10.1586/14779072.2014.972941  1
2014 Gaetani R, Feyen DA, Doevendans PA, Gremmels H, Forte E, Fledderus JO, Ramjankhan FZ, Messina E, Sussman MA, Giacomello A, Sluijter JP. Different types of cultured human adult cardiac progenitor cells have a high degree of transcriptome similarity. Journal of Cellular and Molecular Medicine. 18: 2147-51. PMID 25311343 DOI: 10.1111/Jcmm.12458  1
2014 Panopoulos A, Pacios-Bras C, Choi J, Yenjerla M, Sussman MA, Fotedar R, Margolis RL. Failure of cell cleavage induces senescence in tetraploid primary cells. Molecular Biology of the Cell. 25: 3105-18. PMID 25143403 DOI: 10.1091/Mbc.E14-03-0844  1
2014 Sin J, Puccini JM, Huang C, Konstandin MH, Gilbert PE, Sussman MA, Gottlieb RA, Feuer R. The impact of juvenile coxsackievirus infection on cardiac progenitor cells and postnatal heart development. Plos Pathogens. 10: e1004249. PMID 25079373 DOI: 10.1371/Journal.Ppat.1004249  1
2014 Hariharan N, Sussman MA. Pin1: a molecular orchestrator in the heart. Trends in Cardiovascular Medicine. 24: 256-62. PMID 25070718 DOI: 10.1016/J.Tcm.2014.05.010  1
2014 Anderson ME, Goldhaber J, Houser SR, Puceat M, Sussman MA. Embryonic stem cell-derived cardiac myocytes are not ready for human trials. Circulation Research. 115: 335-8. PMID 24935962 DOI: 10.1161/Circresaha.114.304616  1
2014 Din S, Konstandin MH, Johnson B, Emathinger J, Völkers M, Toko H, Collins B, Ormachea L, Samse K, Kubli DA, De La Torre A, Kraft AS, Gustafsson AB, Kelly DP, Sussman MA. Metabolic dysfunction consistent with premature aging results from deletion of Pim kinases. Circulation Research. 115: 376-87. PMID 24916111 DOI: 10.1161/Circresaha.115.304441  1
2014 Hariharan N, Sussman MA. Stressing on the nucleolus in cardiovascular disease. Biochimica Et Biophysica Acta. 1842: 798-801. PMID 24514103 DOI: 10.1016/J.Bbadis.2013.09.016  1
2014 Völkers M, Doroudgar S, Nguyen N, Konstandin MH, Quijada P, Din S, Ornelas L, Thuerauf DJ, Gude N, Friedrich K, Herzig S, Glembotski CC, Sussman MA. PRAS40 prevents development of diabetic cardiomyopathy and improves hepatic insulin sensitivity in obesity. Embo Molecular Medicine. 6: 57-65. PMID 24408966 DOI: 10.1002/Emmm.201303183  1
2014 Toko H, Hariharan N, Konstandin MH, Ormachea L, McGregor M, Gude NA, Sundararaman B, Joyo E, Joyo AY, Collins B, Din S, Mohsin S, Uchida T, Sussman MA. Differential regulation of cellular senescence and differentiation by prolyl isomerase Pin1 in cardiac progenitor cells. The Journal of Biological Chemistry. 289: 5348-56. PMID 24375406 DOI: 10.1074/Jbc.M113.526442  1
2014 McGregor M, Hariharan N, Joyo AY, Margolis RL, Sussman MA. CENP-A is essential for cardiac progenitor cell proliferation. Cell Cycle (Georgetown, Tex.). 13: 739-48. PMID 24362315 DOI: 10.4161/Cc.27549  1
2014 Mohsin S, Wu JC, Sussman MA. Predicting the future with stem cells. Circulation. 129: 136-8. PMID 24249719 DOI: 10.1161/Circulationaha.113.007045  1
2014 Khan M, Mohsin S, Toko H, Alkatib M, Nguyen J, Truffa S, Gude N, Chuprun K, Tilley DG, Koch WJ, Sussman MA. Cardiac progenitor cells engineered with βARKct have enhanced β-adrenergic tolerance. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 178-85. PMID 24002692 DOI: 10.1038/Mt.2013.200  1
2013 Völkers M, Sussman M. mTOR/PRAS40 interaction: hypertrophy or proliferation. Cell Cycle (Georgetown, Tex.). 12: 3579-80. PMID 24131922 DOI: 10.4161/Cc.26822  1
2013 Mohsin S, Khan M, Nguyen J, Alkatib M, Siddiqi S, Hariharan N, Wallach K, Monsanto M, Gude N, Dembitsky W, Sussman MA. Rejuvenation of human cardiac progenitor cells with Pim-1 kinase. Circulation Research. 113: 1169-79. PMID 24044948 DOI: 10.1161/Circresaha.113.302302  1
2013 Völkers M, Konstandin MH, Doroudgar S, Toko H, Quijada P, Din S, Joyo A, Ornelas L, Samse K, Thuerauf DJ, Gude N, Glembotski CC, Sussman MA. Mechanistic target of rapamycin complex 2 protects the heart from ischemic damage. Circulation. 128: 2132-44. PMID 24008870 DOI: 10.1161/Circulationaha.113.003638  1
2013 Siddiqi S, Sussman MA. Cell and gene therapy for severe heart failure patients: the time and place for Pim-1 kinase. Expert Review of Cardiovascular Therapy. 11: 949-57. PMID 23984924 DOI: 10.1586/14779072.2013.814830  1
2013 Konstandin MH, Völkers M, Collins B, Quijada P, Quintana M, De La Torre A, Ormachea L, Din S, Gude N, Toko H, Sussman MA. Fibronectin contributes to pathological cardiac hypertrophy but not physiological growth. Basic Research in Cardiology. 108: 375. PMID 23912225 DOI: 10.1007/S00395-013-0375-8  1
2013 Völkers M, Toko H, Doroudgar S, Din S, Quijada P, Joyo AY, Ornelas L, Joyo E, Thuerauf DJ, Konstandin MH, Gude N, Glembotski CC, Sussman MA. Pathological hypertrophy amelioration by PRAS40-mediated inhibition of mTORC1. Proceedings of the National Academy of Sciences of the United States of America. 110: 12661-6. PMID 23842089 DOI: 10.1073/Pnas.1301455110  1
2013 Thomas RL, Roberts DJ, Kubli DA, Lee Y, Quinsay MN, Owens JB, Fischer KM, Sussman MA, Miyamoto S, Gustafsson ÅB. Loss of MCL-1 leads to impaired autophagy and rapid development of heart failure. Genes & Development. 27: 1365-77. PMID 23788623 DOI: 10.1101/Gad.215871.113  1
2013 Konstandin MH, Toko H, Gastelum GM, Quijada P, De La Torre A, Quintana M, Collins B, Din S, Avitabile D, Völkers M, Gude N, Fässler R, Sussman MA. Fibronectin is essential for reparative cardiac progenitor cell response after myocardial infarction. Circulation Research. 113: 115-25. PMID 23652800 DOI: 10.1161/Circresaha.113.301152  1
2013 Din S, Mason M, Völkers M, Johnson B, Cottage CT, Wang Z, Joyo AY, Quijada P, Erhardt P, Magnuson NS, Konstandin MH, Sussman MA. Pim-1 preserves mitochondrial morphology by inhibiting dynamin-related protein 1 translocation. Proceedings of the National Academy of Sciences of the United States of America. 110: 5969-74. PMID 23530233 DOI: 10.1073/Pnas.1213294110  1
2013 Toko H, Konstandin MH, Doroudgar S, Ormachea L, Joyo E, Joyo AY, Din S, Gude NA, Collins B, Völkers M, Thuerauf DJ, Glembotski CC, Chen CH, Lu KP, Müller OJ, ... ... Sussman MA, et al. Regulation of cardiac hypertrophic signaling by prolyl isomerase Pin1. Circulation Research. 112: 1244-52. PMID 23487407 DOI: 10.1161/Circresaha.113.301084  1
2013 Khan M, Mohsin S, Avitabile D, Siddiqi S, Nguyen J, Wallach K, Quijada P, McGregor M, Gude N, Alvarez R, Tilley DG, Koch WJ, Sussman MA. β-Adrenergic regulation of cardiac progenitor cell death versus survival and proliferation. Circulation Research. 112: 476-86. PMID 23243208 DOI: 10.1161/Circresaha.112.280735  1
2013 Williams AR, Hatzistergos KE, Addicott B, McCall F, Carvalho D, Suncion V, Morales AR, Da Silva J, Sussman MA, Heldman AW, Hare JM. Enhanced effect of combining human cardiac stem cells and bone marrow mesenchymal stem cells to reduce infarct size and to restore cardiac function after myocardial infarction. Circulation. 127: 213-23. PMID 23224061 DOI: 10.1161/Circulationaha.112.131110  1
2012 Tufan H, Zhang XH, Haghshenas N, Sussman MA, Cleemann L, Morad M. Cardiac progenitor cells engineered with Pim-1 (CPCeP) develop cardiac phenotypic electrophysiological properties as they are co-cultured with neonatal myocytes. Journal of Molecular and Cellular Cardiology. 53: 695-706. PMID 23010478 DOI: 10.1016/J.Yjmcc.2012.08.008  1
2012 Cottage CT, Neidig L, Sundararaman B, Din S, Joyo AY, Bailey B, Gude N, Hariharan N, Sussman MA. Increased mitotic rate coincident with transient telomere lengthening resulting from pim-1 overexpression in cardiac progenitor cells. Stem Cells (Dayton, Ohio). 30: 2512-22. PMID 22915504 DOI: 10.1002/Stem.1211  1
2012 Mohsin S, Khan M, Toko H, Bailey B, Cottage CT, Wallach K, Nag D, Lee A, Siddiqi S, Lan F, Fischer KM, Gude N, Quijada P, Avitabile D, Truffa S, ... ... Sussman MA, et al. Human cardiac progenitor cells engineered with Pim-I kinase enhance myocardial repair. Journal of the American College of Cardiology. 60: 1278-87. PMID 22841153 DOI: 10.1016/J.Jacc.2012.04.047  1
2012 Bailey B, Fransioli J, Gude NA, Alvarez R, Zhang X, Zhan X, Gustafsson ÅB, Sussman MA. Sca-1 knockout impairs myocardial and cardiac progenitor cell function. Circulation Research. 111: 750-60. PMID 22800687 DOI: 10.1161/Circresaha.112.274662  1
2012 Quijada P, Toko H, Fischer KM, Bailey B, Reilly P, Hunt KD, Gude NA, Avitabile D, Sussman MA. Preservation of myocardial structure is enhanced by pim-1 engineering of bone marrow cells. Circulation Research. 111: 77-86. PMID 22619278 DOI: 10.1161/Circresaha.112.265207  1
2012 Houser SR, Margulies KB, Murphy AM, Spinale FG, Francis GS, Prabhu SD, Rockman HA, Kass DA, Molkentin JD, Sussman MA, Koch WJ, Koch W. Animal models of heart failure: a scientific statement from the American Heart Association. Circulation Research. 111: 131-50. PMID 22595296 DOI: 10.1161/Res.0B013E3182582523  1
2012 Sussman MA. Myocardial Isl(+)land: a place with lots of rhythm, but no beat. Circulation Research. 110: 1267-9. PMID 22581917 DOI: 10.1161/Circresaha.112.268995  1
2012 Gude N, Sussman M. Notch signaling and cardiac repair. Journal of Molecular and Cellular Cardiology. 52: 1226-32. PMID 22465038 DOI: 10.1016/J.Yjmcc.2012.03.007  1
2012 Sundararaman B, Avitabile D, Konstandin MH, Cottage CT, Gude N, Sussman MA. Asymmetric chromatid segregation in cardiac progenitor cells is enhanced by Pim-1 kinase. Circulation Research. 110: 1169-73. PMID 22441844 DOI: 10.1161/Circresaha.112.267716  1
2012 Völkers M, Dolatabadi N, Gude N, Most P, Sussman MA, Hassel D. Orai1 deficiency leads to heart failure and skeletal myopathy in zebrafish. Journal of Cell Science. 125: 287-94. PMID 22302996 DOI: 10.1242/Jcs.090464  1
2012 Ruller CM, Tabor-Godwin JM, Van Deren DA, Robinson SM, Maciejewski S, Gluhm S, Gilbert PE, An N, Gude NA, Sussman MA, Whitton JL, Feuer R. Neural stem cell depletion and CNS developmental defects after enteroviral infection. The American Journal of Pathology. 180: 1107-20. PMID 22214838 DOI: 10.1016/J.Ajpath.2011.11.016  1
2011 Mohsin S, Siddiqi S, Collins B, Sussman MA. Empowering adult stem cells for myocardial regeneration. Circulation Research. 109: 1415-28. PMID 22158649 DOI: 10.1161/Circresaha.111.243071  1
2011 Meloche J, Paulin R, Courboulin A, Lambert C, Barrier M, Bonnet P, Bisserier M, Roy M, Sussman MA, Agharazii M, Bonnet S. RAGE-dependent activation of the oncoprotein Pim1 plays a critical role in systemic vascular remodeling processes. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 2114-24. PMID 21680901 DOI: 10.1161/Atvbaha.111.230573  1
2011 Paulin R, Courboulin A, Meloche J, Mainguy V, Dumas de la Roque E, Saksouk N, Côté J, Provencher S, Sussman MA, Bonnet S. Signal transducers and activators of transcription-3/pim1 axis plays a critical role in the pathogenesis of human pulmonary arterial hypertension. Circulation. 123: 1205-15. PMID 21382889 DOI: 10.1161/Circulationaha.110.963314  1
2011 Fischer KM, Din S, Gude N, Konstandin MH, Wu W, Quijada P, Sussman MA. Cardiac progenitor cell commitment is inhibited by nuclear Akt expression. Circulation Research. 108: 960-70. PMID 21350213 DOI: 10.1161/Circresaha.110.237156  1
2011 Fischer KM, Cottage CT, Konstandin MH, Völkers M, Khan M, Sussman MA. Pim-1 kinase inhibits pathological injury by promoting cardioprotective signaling. Journal of Molecular and Cellular Cardiology. 51: 554-8. PMID 21255581 DOI: 10.1016/J.Yjmcc.2011.01.004  1
2011 Cheng Z, Völkers M, Din S, Avitabile D, Khan M, Gude N, Mohsin S, Bo T, Truffa S, Alvarez R, Mason M, Fischer KM, Konstandin MH, Zhang XK, Heller Brown J, ... Sussman MA, et al. Mitochondrial translocation of Nur77 mediates cardiomyocyte apoptosis. European Heart Journal. 32: 2179-88. PMID 21228009 DOI: 10.1093/Eurheartj/Ehq496  1
2011 Green T, Vera C, Sussman MA, Martone M, Sung LA. Mechanobiology of erythrocytes from adult mice homozygous for a targeted disruption of the e-tmod gene at exon 1 Cellular and Molecular Bioengineering. 4: 637-647. DOI: 10.1007/S12195-011-0203-X  1
2010 Tabor-Godwin JM, Ruller CM, Bagalso N, An N, Pagarigan RR, Harkins S, Gilbert PE, Kiosses WB, Gude NA, Cornell CT, Doran KS, Sussman MA, Whitton JL, Feuer R. A novel population of myeloid cells responding to coxsackievirus infection assists in the dissemination of virus within the neonatal CNS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 8676-91. PMID 20573913 DOI: 10.1523/Jneurosci.1860-10.2010  1
2010 Borillo GA, Mason M, Quijada P, Völkers M, Cottage C, McGregor M, Din S, Fischer K, Gude N, Avitabile D, Barlow S, Alvarez R, Truffa S, Whittaker R, Glassy MS, ... ... Sussman MA, et al. Pim-1 kinase protects mitochondrial integrity in cardiomyocytes. Circulation Research. 106: 1265-74. PMID 20203306 DOI: 10.1161/Circresaha.109.212035  1
2010 Voelkers M, Salz M, Herzog N, Frank D, Dolatabadi N, Frey N, Gude N, Friedrich O, Koch WJ, Katus HA, Sussman MA, Most P. Orai1 and Stim1 regulate normal and hypertrophic growth in cardiomyocytes Journal of Molecular and Cellular Cardiology. 48: 1329-1334. PMID 20138887 DOI: 10.1016/J.Yjmcc.2010.01.020  1
2010 Adam O, Lavall D, Theobald K, Hohl M, Grube M, Ameling S, Sussman MA, Rosenkranz S, Kroemer HK, Schäfers HJ, Böhm M, Laufs U. Rac1-induced connective tissue growth factor regulates connexin 43 and N-cadherin expression in atrial fibrillation. Journal of the American College of Cardiology. 55: 469-80. PMID 20117462 DOI: 10.1016/J.Jacc.2009.08.064  1
2010 Huang C, Zhang X, Ramil JM, Rikka S, Kim L, Lee Y, Gude NA, Thistlethwaite PA, Sussman MA, Gottlieb RA, Gustafsson AB. Juvenile exposure to anthracyclines impairs cardiac progenitor cell function and vascularization resulting in greater susceptibility to stress-induced myocardial injury in adult mice. Circulation. 121: 675-83. PMID 20100968 DOI: 10.1161/Circulationaha.109.902221  1
2010 Cottage CT, Bailey B, Fischer KM, Avitabile D, Avitable D, Collins B, Tuck S, Quijada P, Gude N, Alvarez R, Muraski J, Sussman MA. Cardiac progenitor cell cycling stimulated by pim-1 kinase. Circulation Research. 106: 891-901. PMID 20075333 DOI: 10.1161/Circresaha.109.208629  1
2010 Belmont PJ, Chen WJ, San Pedro MN, Thuerauf DJ, Lowe NG, Gude N, Hilton B, Wolkowicz R, Sussman MA, Glembotski CC. Roles for endoplasmic reticulum-associated degradation and the novel endoplasmic reticulum stress response gene derlin-3 in the ischemic heart Circulation Research. 106: 307-316. PMID 19940266 DOI: 10.1161/Circresaha.109.203901  1
2009 Bailey B, Izarra A, Alvarez R, Fischer KM, Cottage CT, Quijada P, Díez-Juan A, Sussman MA. Cardiac stem cell genetic engineering using the alphaMHC promoter. Regenerative Medicine. 4: 823-33. PMID 19903002 DOI: 10.2217/Rme.09.51  1
2009 Fischer KM, Cottage CT, Wu W, Din S, Gude NA, Avitabile D, Quijada P, Collins BL, Fransioli J, Sussman MA. Enhancement of myocardial regeneration through genetic engineering of cardiac progenitor cells expressing Pim-1 kinase. Circulation. 120: 2077-87. PMID 19901187 DOI: 10.1161/Circulationaha.109.884403  1
2009 Miyamoto S, Rubio M, Sussman MA. Nuclear and mitochondrial signalling Akts in cardiomyocytes. Cardiovascular Research. 82: 272-85. PMID 19279164 DOI: 10.1093/Cvr/Cvp087  1
2009 Rubio M, Avitabile D, Fischer K, Emmanuel G, Gude N, Miyamoto S, Mishra S, Schaefer EM, Brown JH, Sussman MA. Cardioprotective stimuli mediate phosphoinositide 3-kinase and phosphoinositide dependent kinase 1 nuclear accumulation in cardiomyocytes. Journal of Molecular and Cellular Cardiology. 47: 96-103. PMID 19269295 DOI: 10.1016/J.Yjmcc.2009.02.022  1
2009 Whittaker R, Glassy MS, Gude N, Sussman MA, Gottlieb RA, Glembotski CC. Kinetics of the translocation and phosphorylation of alphaB-crystallin in mouse heart mitochondria during ex vivo ischemia. American Journal of Physiology. Heart and Circulatory Physiology. 296: H1633-42. PMID 19252088 DOI: 10.1152/Ajpheart.01227.2008  1
2008 McKeown CR, Nowak RB, Moyer J, Sussman MA, Fowler VM. Tropomodulin1 is required in the heart but not the yolk sac for mouse embryonic development. Circulation Research. 103: 1241-8. PMID 18927466 DOI: 10.1161/Circresaha.108.178749  1
2008 Muraski JA, Fischer KM, Wu W, Cottage CT, Quijada P, Mason M, Din S, Gude N, Alvarez R, Rota M, Kajstura J, Wang Z, Schaefer E, Chen X, MacDonnel S, ... ... Sussman MA, et al. Pim-1 kinase antagonizes aspects of myocardial hypertrophy and compensation to pathological pressure overload. Proceedings of the National Academy of Sciences of the United States of America. 105: 13889-94. PMID 18784362 DOI: 10.1073/Pnas.0709135105  1
2008 Siddiqi S, Gude N, Hosoda T, Muraski J, Rubio M, Emmanuel G, Fransioli J, Vitale S, Parolin C, D'Amario D, Schaefer E, Kajstura J, Leri A, Anversa P, Sussman MA. Myocardial induction of nucleostemin in response to postnatal growth and pathological challenge. Circulation Research. 103: 89-97. PMID 18519946 DOI: 10.1161/Circresaha.107.169334  1
2008 Gude NA, Emmanuel G, Wu W, Cottage CT, Fischer K, Quijada P, Muraski JA, Alvarez R, Rubio M, Schaefer E, Sussman MA. Activation of Notch-mediated protective signaling in the myocardium. Circulation Research. 102: 1025-35. PMID 18369158 DOI: 10.1161/Circresaha.107.164749  1
2008 Fransioli J, Bailey B, Gude NA, Cottage CT, Muraski JA, Emmanuel G, Wu W, Alvarez R, Rubio M, Ottolenghi S, Schaefer E, Sussman MA. Evolution of the c-kit-positive cell response to pathological challenge in the myocardium. Stem Cells (Dayton, Ohio). 26: 1315-24. PMID 18308948 DOI: 10.1634/Stemcells.2007-0751  1
2008 Muraski JA, Rota M, Misao Y, Fransioli J, Cottage C, Gude N, Esposito G, Delucchi F, Arcarese M, Alvarez R, Siddiqi S, Emmanuel GN, Wu W, Fischer K, Martindale JJ, ... ... Sussman MA, et al. Corrigendum: Pim-1 regulates cardiomyocyte survival downstream of Akt (Nature Medicine (2007) 13, (1467-1475)) Nature Medicine. 14: 350. DOI: 10.1038/Nm0308-350  1
2007 Muraski JA, Rota M, Misao Y, Fransioli J, Cottage C, Gude N, Esposito G, Delucchi F, Arcarese M, Alvarez R, Siddiqi S, Emmanuel GN, Wu W, Fischer K, Martindale JJ, ... ... Sussman MA, et al. Pim-1 regulates cardiomyocyte survival downstream of Akt Nature Medicine. 13: 1467-1475. PMID 18037896 DOI: 10.1038/Nm1671  1
2006 Gude N, Muraski J, Rubio M, Kajstura J, Schaefer E, Anversa P, Sussman MA. Akt promotes increased cardiomyocyte cycling and expansion of the cardiac progenitor cell population. Circulation Research. 99: 381-8. PMID 16840722 DOI: 10.1161/01.Res.0000236754.21499.1C  1
2006 Thuerauf DJ, Marcinko M, Gude N, Rubio M, Sussman MA, Glembotski CC. Activation of the unfolded protein response in infarcted mouse heart and hypoxic cultured cardiac myocytes. Circulation Research. 99: 275-82. PMID 16794188 DOI: 10.1161/01.Res.0000233317.70421.03  1
2005 Rota M, Boni A, Urbanek K, Padin-Iruegas ME, Kajstura TJ, Fiore G, Kubo H, Sonnenblick EH, Musso E, Houser SR, Leri A, Sussman MA, Anversa P. Nuclear targeting of Akt enhances ventricular function and myocyte contractility. Circulation Research. 97: 1332-41. PMID 16293788 DOI: 10.1161/01.Res.0000196568.11624.Ae  1
2005 Kato T, Muraski J, Chen Y, Tsujita Y, Wall J, Glembotski CC, Schaefer E, Beckerle M, Sussman MA. Atrial natriuretic peptide promotes cardiomyocyte survival by cGMP-dependent nuclear accumulation of zyxin and Akt. The Journal of Clinical Investigation. 115: 2716-30. PMID 16200208 DOI: 10.1172/Jci24280  1
2005 Buscemi N, Murray C, Doherty-Kirby A, Lajoie G, Sussman MA, Van Eyk JE. Myocardial subproteomic analysis of a constitutively active Rac1-expressing transgenic mouse with lethal myocardial hypertrophy. American Journal of Physiology. Heart and Circulatory Physiology. 289: H2325-33. PMID 16155095 DOI: 10.1152/Ajpheart.01041.2004  1
2004 Shiraishi I, Melendez J, Ahn Y, Skavdahl M, Murphy E, Welch S, Schaefer E, Walsh K, Rosenzweig A, Torella D, Nurzynska D, Kajstura J, Leri A, Anversa P, Sussman MA. Nuclear targeting of Akt enhances kinase activity and survival of cardiomyocytes. Circulation Research. 94: 884-91. PMID 14988230 DOI: 10.1161/01.Res.0000124394.01180.Be  1
2004 McMullen M, Keller R, Sussman M, Pumiglia K. Vascular endothelial growth factor-mediated activation of p38 is dependent upon Src and RAFTK/Pyk2. Oncogene. 23: 1275-82. PMID 14676843 DOI: 10.1038/Sj.Onc.1207243  1
2003 Buscemi N, Doherty-Kirby A, Sussman MA, Lajoie G, Van Eyk JE. Proteomic analysis of Rac1 transgenic mice displaying dilated cardiomyopathy reveals an increase in creatine kinase M-chain protein abundance. Molecular and Cellular Biochemistry. 251: 145-51. PMID 14575316 DOI: 10.1007/978-1-4419-9238-3_20  1
2003 Avraham HK, Lee TH, Koh Y, Kim TA, Jiang S, Sussman M, Samarel AM, Avraham S. Vascular endothelial growth factor regulates focal adhesion assembly in human brain microvascular endothelial cells through activation of the focal adhesion kinase and related adhesion focal tyrosine kinase Journal of Biological Chemistry. 278: 36661-36668. PMID 12844492 DOI: 10.1074/Jbc.M301253200  1
2003 Plank DM, Yatani A, Ritsu H, Witt S, Glascock B, Lalli MJ, Periasamy M, Fiset C, Benkusky N, Valdivia HH, Sussman MA. Calcium dynamics in the failing heart: restoration by beta-adrenergic receptor blockade. American Journal of Physiology. Heart and Circulatory Physiology. 285: H305-15. PMID 12649072 DOI: 10.1152/Ajpheart.00425.2002  1
2003 Goldsmith EC, Carver W, McFadden A, Goldsmith JG, Price RL, Sussman M, Lorell BH, Cooper G, Borg TK. Integrin shedding as a mechanism of cellular adaptation during cardiac growth American Journal of Physiology - Heart and Circulatory Physiology. 284: H2227-H2234. PMID 12573995 DOI: 10.1152/Ajpheart.00920.2002  1
2002 Sussman MA, McCulloch A, Borg TK. Dance band on the Titanic: Biomechanical signaling in cardiac hypertrophy Circulation Research. 91: 888-898. PMID 12433833 DOI: 10.1161/01.Res.0000041680.43270.F8  1
2002 Melendez J, Welch S, Schaefer E, Moravec CS, Avraham S, Avraham H, Sussman MA. Activation of pyk2/related focal adhesion tyrosine kinase and focal adhesion kinase in cardiac remodeling. The Journal of Biological Chemistry. 277: 45203-10. PMID 12228222 DOI: 10.1074/Jbc.M204886200  1
2002 Welch S, Plank D, Witt S, Glascock B, Schaefer E, Chimenti S, Andreoli AM, Limana F, Leri A, Kajstura J, Anversa P, Sussman MA. Cardiac-specific IGF-1 expression attenuates dilated cardiomyopathy in tropomodulin-overexpressing transgenic mice. Circulation Research. 90: 641-8. PMID 11934830 DOI: 10.1161/01.Res.0000013780.77774.75  1
2001 Lalli MJ, Yong J, Prasad V, Hashimoto K, Plank D, Babu GJ, Kirkpatrick D, Walsh RA, Sussman M, Yatani A, Marbán E, Periasamy M. Sarcoplasmic reticulum Ca(2+) atpase (SERCA) 1a structurally substitutes for SERCA2a in the cardiac sarcoplasmic reticulum and increases cardiac Ca(2+) handling capacity. Circulation Research. 89: 160-7. PMID 11463723  1
2001 Camper-Kirby D, Welch S, Walker A, Shiraishi I, Setchell KD, Schaefer E, Kajstura J, Anversa P, Sussman MA. Myocardial Akt activation and gender: increased nuclear activity in females versus males. Circulation Research. 88: 1020-7. PMID 11375271 DOI: 10.1161/Hh1001.090858  1
2001 Ehler E, Horowits R, Zuppinger C, Price RL, Perriard E, Leu M, Caroni P, Sussman M, Eppenberger HM, Perriard JC. Alterations at the intercalated disk associated with the absence of muscle LIM protein. The Journal of Cell Biology. 153: 763-72. PMID 11352937 DOI: 10.1083/Jcb.153.4.763  1
2000 Yang J, Moravec CS, Sussman MA, DiPaola NR, Fu D, Hawthorn L, Mitchell CA, Young JB, Francis GS, McCarthy PM, Bond M. Decreased SLIM1 expression and increased gelsolin expression in failing human hearts measured by high-density oligonucleotide arrays Circulation. 102: 3046-3052. PMID 11120693 DOI: 10.1161/01.Cir.102.25.3046  1
2000 Babu GJ, Lalli JM, Sussman MA, Sadoshima Ji, Periasamy M. Phosphorylation of Elk-1 by MEK/ERK pathway is necessary for c-fos gene activation during cardiac myocyte hypertrophy Journal of Molecular and Cellular Cardiology. 32: 1447-1457. PMID 10900171 DOI: 10.1006/Jmcc.2000.1185  1
2000 Greene AL, Lalli MJ, Ji Y, Babu GJ, Grupp I, Sussman M, Periasamy M. Overexpression of SERCA2b in the heart leads to an increase in sarcoplasmic reticulum calcium transport function and increased cardiac contractility Journal of Biological Chemistry. 275: 24722-24727. PMID 10816568 DOI: 10.1074/jbc.M001783200  1
2000 Sussman MA, Welch S, Walker A, Klevitsky R, Hewett TE, Price RL, Schaefer E, Yager K. Altered focal adhesion regulation correlates with cardiomyopathy in mice expressing constitutively active rac1. The Journal of Clinical Investigation. 105: 875-86. PMID 10749567 DOI: 10.1172/Jci8497  1
2000 Sussman MA, Welch S, Walker A, Klevitsky R, Hewett TE, Witt SA, Kimball TR, Price R, Lim HW, Molkentin JD. Hypertrophic defect unmasked by calcineurin expression in asymptomatic tropomodulin overexpressing transgenic mice. Cardiovascular Research. 46: 90-101. PMID 10727657 DOI: 10.1016/S0008-6363(99)00422-8  1
1999 Sussman MA, Welch S, Gude N, Khoury PR, Daniels SR, Kirkpatrick D, Walsh RA, Price RL, Lim HW, Molkentin JD. Pathogenesis of dilated cardiomyopathy: molecular, structural, and population analyses in tropomodulin-overexpressing transgenic mice. The American Journal of Pathology. 155: 2101-13. PMID 10595939 DOI: 10.1016/S0002-9440(10)65528-9  1
1998 Sussman MA, Lim HW, Gude N, Taigen T, Olson EN, Robbins J, Colbert MC, Gualberto A, Wieczorek DF, Molkentin JD. Prevention of cardiac hypertrophy in mice by calcineurin inhibition. Science (New York, N.Y.). 281: 1690-3. PMID 9733519 DOI: 10.1126/Science.281.5383.1690  1
1998 Sussman MA, Baqué S, Uhm CS, Daniels MP, Price RL, Simpson D, Terracio L, Kedes L. Altered expression of tropomodulin in cardiomyocytes disrupts the sarcomeric structure of myofibrils. Circulation Research. 82: 94-105. PMID 9440708 DOI: 10.1161/01.Res.82.1.94  1
1998 Sussman MA, Welch S, Cambon N, Klevitsky R, Hewett TE, Price R, Witt SA, Kimball TR. Myofibril degeneration caused by tropomodulin overexpression leads to dilated cardiomyopathy in juvenile mice. The Journal of Clinical Investigation. 101: 51-61. PMID 9421465 DOI: 10.1172/Jci1167  1
1997 Sussman MA, Hamm-Alvarez SF, Vilalta PM, Welch S, Kedes L. Involvement of phosphorylation in doxorubicin-mediated myofibril degeneration: An immunofluorescence microscopy analysis Circulation Research. 80: 52-61. PMID 8978322 DOI: 10.1161/01.Res.80.1.52  1
1996 Sussman MA, McAvoy JW, Rudisill M, Swanson B, Lyons GE, Kedes L, Blanks J. Lens tropomodulin: Developmental expression during differentiation Experimental Eye Research. 63: 223-232. PMID 8983980 DOI: 10.1006/Exer.1996.0111  1
1996 Sussman MA, Ito M, Daniels MP, Flucher B, Buranen S, Kedes L. Chicken skeletal muscle tropomodulin: novel localization and characterization. Cell and Tissue Research. 285: 287-96. PMID 8766165 DOI: 10.1007/S004410050646  1
1995 Ito M, Swanson B, Sussman MA, Kedes L, Lyons G. Cloning of tropomodulin cDNA and localization of gene transcripts during mouse embryogenesis Developmental Biology. 167: 317-328. PMID 7851652 DOI: 10.1006/Dbio.1995.1026  1
1994 Sussman MA, Sakhi S, Barrientos P, Ito M, Kedes L. Tropomodulin in rat cardiac muscle: Localization of protein is independent of messenger RNA distribution during myofibrillar development Circulation Research. 75: 221-232. PMID 8033336 DOI: 10.1161/01.Res.75.2.221  1
1994 Sussman MA, Sakhi S, Tocco G, Najm I, Baudry M, Kedes L, Schreiber SS. Neural tropomodulin: developmental expression and effect of seizure activity. Brain Research. Developmental Brain Research. 80: 45-53. PMID 7955359 DOI: 10.1016/0165-3806(94)90088-4  1
1993 Sussman MA, Bilak M, Kedes L, Engel WK, Askanas V. Tropomodulin is highly concentrated at the postsynaptic domain of human and rat neuromuscular junctions. Experimental Cell Research. 209: 388-91. PMID 8262158 DOI: 10.1006/Excr.1993.1325  1
1992 Sussman MA, Fowler VM. Tropomodulin binding to tropomyosins. Isoform-specific differences in affinity and stoichiometry European Journal of Biochemistry. 205: 355-362. PMID 1555594 DOI: 10.1111/J.1432-1033.1992.Tb16787.X  1
1992 Sung LA, Fowler VM, Lambert K, Sussman MA, Karr D, Chien S. Molecular cloning and characterization of human fetal liver tropomodulin. A tropomyosin-binding protein. The Journal of Biological Chemistry. 267: 2616-21. PMID 1370827  1
1990 Sussman MA, Battenberg E, Bloom FE, Fowler VM. Identification of two nerve growth factor-induced polypeptides in PC12 cells. Journal of Molecular Neuroscience : Mn. 2: 163-74. PMID 2275847 DOI: 10.1007/Bf02896841  1
1990 Shubin RA, Sussman MA, Fleming JO, Stohlman SA. Relapsing encephalomyelitis following transfer of partial immunity to JHM virus. Microbial Pathogenesis. 8: 305-14. PMID 1977071 DOI: 10.1016/0882-4010(90)90089-9  1
1989 Sussman MA, Shubin RA, Kyuwa S, Stohlman SA. T-cell-mediated clearance of mouse hepatitis virus strain JHM from the central nervous system. Journal of Virology. 63: 3051-6. PMID 2542613 DOI: 10.1128/Jvi.63.7.3051-3056.1989  1
1989 Fleming JO, Shubin RA, Sussman MA, Casteel N, Stohlman SA. Monoclonal antibodies to the matrix (E1) glycoprotein of mouse hepatitis virus protect mice from encephalitis. Virology. 168: 162-7. PMID 2535900 DOI: 10.1016/0042-6822(89)90415-7  1
1988 Stohlman SA, Sussman MA, Matsushima GK, Shubin RA, Erlich SS. Delayed-type hypersensitivity response in the central nervous system during JHM virus infection requires viral specificity for protection. Journal of Neuroimmunology. 19: 255-68. PMID 2842378 DOI: 10.1016/0165-5728(88)90007-0  1
1987 Sussman MA, Fleming JO, Allen H, Stohlman SA. Immune mediated clearance of JHM virus from the central nervous system. Advances in Experimental Medicine and Biology. 218: 399-410. PMID 2829552 DOI: 10.1007/978-1-4684-1280-2_49  1
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