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Susan Biggins - Publications

Affiliations: 
Biochemistry Fred Hutchinson Cancer Research Center, Seattle, WA, United States 
Area:
Regulation of chromosome segregation
Website:
http://sharedresources.fhcrc.org/profile/biggins-sue
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48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Koch LB, Opoku KN, Deng Y, Barber A, Littleton AJ, London N, Biggins S, Asbury CL. Autophosphorylation is sufficient to release Mps1 kinase from native kinetochores. Proceedings of the National Academy of Sciences of the United States of America. PMID 31405987 DOI: 10.1073/Pnas.1901653116  0.346
2019 Leontiou I, London N, May KM, Ma Y, Grzesiak L, Medina-Pritchard B, Amin P, Jeyaprakash AA, Biggins S, Hardwick KG. The Bub1-TPR Domain Interacts Directly with Mad3 to Generate Robust Spindle Checkpoint Arrest. Current Biology : Cb. PMID 31257143 DOI: 10.1016/J.Cub.2019.06.011  0.345
2018 Lang J, Barber A, Biggins S. An assay for de novo kinetochore assembly reveals a key role for the CENP-T pathway in budding yeast. Elife. 7. PMID 30117803 DOI: 10.7554/Elife.37819  0.356
2018 Gupta A, Evans RK, Koch LB, Littleton AJ, Biggins S. Purification of kinetochores from the budding yeast Saccharomyces cerevisiae. Methods in Cell Biology. 144: 349-370. PMID 29804677 DOI: 10.1016/Bs.Mcb.2018.03.023  0.399
2017 Tubman ES, Biggins S, Odde DJ. Stochastic Modeling Yields a Mechanistic Framework for Spindle Attachment Error Correction in Budding Yeast Mitosis. Cell Systems. PMID 28601560 DOI: 10.1016/J.Cels.2017.05.003  0.308
2017 Opoku KN, Koch L, Biggins S, Asbury CL. What Silences the Spindle Checkpoint? A Single Particle Study Biophysical Journal. 112: 431a. DOI: 10.1016/J.Bpj.2016.11.2304  0.398
2016 Miller MP, Asbury CL, Biggins S. A TOG Protein Confers Tension Sensitivity to Kinetochore-Microtubule Attachments. Cell. 165: 1428-39. PMID 27156448 DOI: 10.1016/J.Cell.2016.04.030  0.332
2015 Biggins S. Under Tension: Kinetochores and Basic Research. Genetics. 200: 681-2. PMID 26170442 DOI: 10.1534/Genetics.115.178467  0.304
2014 Umbreit NT, Miller MP, Tien JF, Ortolá JC, Gui L, Lee KK, Biggins S, Asbury CL, Davis TN. Kinetochores require oligomerization of Dam1 complex to maintain microtubule attachments against tension and promote biorientation. Nature Communications. 5: 4951. PMID 25236177 DOI: 10.1038/Ncomms5951  0.369
2014 Sarangapani KK, Duro E, Deng Y, Alves Fde L, Ye Q, Opoku KN, Ceto S, Rappsilber J, Corbett KD, Biggins S, Marston AL, Asbury CL. Sister kinetochores are mechanically fused during meiosis I in yeast. Science (New York, N.Y.). 346: 248-51. PMID 25213378 DOI: 10.1126/Science.1256729  0.318
2014 Driver JW, Powers AF, Sarangapani KK, Biggins S, Asbury CL. Measuring kinetochore-microtubule interaction in vitro. Methods in Enzymology. 540: 321-37. PMID 24630115 DOI: 10.1016/B978-0-12-397924-7.00018-2  0.404
2014 London N, Biggins S. Mad1 kinetochore recruitment by Mps1-mediated phosphorylation of Bub1 signals the spindle checkpoint Genes and Development. 28: 140-152. PMID 24402315 DOI: 10.1101/Gad.233700.113  0.407
2014 Biggins S, Sarangapani K, Duro E, Deng Y, Opoku K, de Lima Alves F, Rappsilber J, Marston A, Asbury C. Direct Evidence for Sister Kinetochore Fusion in Meiosis I Biophysical Journal. 106: 637a. DOI: 10.1016/J.Bpj.2013.11.3526  0.371
2013 Ng TM, Lenstra TL, Duggan N, Jiang S, Ceto S, Holstege FC, Dai J, Boeke JD, Biggins S. Kinetochore function and chromosome segregation rely on critical residues in histones H3 and H4 in budding yeast. Genetics. 195: 795-807. PMID 24037263 DOI: 10.1534/Genetics.113.152082  0.316
2013 Biggins S. The composition, functions, and regulation of the budding yeast kinetochore. Genetics. 194: 817-46. PMID 23908374 DOI: 10.1534/Genetics.112.145276  0.354
2013 Akiyoshi B, Nelson CR, Biggins S. The aurora B kinase promotes inner and outer kinetochore interactions in budding yeast Genetics. 194: 785-789. PMID 23636741 DOI: 10.1534/Genetics.113.150839  0.321
2013 Akiyoshi B, Nelson CR, Duggan N, Ceto S, Ranish JA, Biggins S. The Mub1/Ubr2 Ubiquitin Ligase Complex Regulates the Conserved Dsn1 Kinetochore Protein Plos Genetics. 9. PMID 23408894 DOI: 10.1371/Journal.Pgen.1003216  0.404
2013 Driver J, Powers A, Sarangapani K, Akiyoshi B, Duggan N, Biggins S, Asbury C. A Single-Molecule Study to Resolve How Kinases Prevent Chromosomal Mis-Segregation Biophysical Journal. 104: 149a. DOI: 10.1016/J.Bpj.2012.11.844  0.334
2012 London N, Ceto S, Ranish JA, Biggins S. Phosphoregulation of Spc105 by Mps1 and PP1 regulates Bub1 localization to kinetochores Current Biology. 22: 900-906. PMID 22521787 DOI: 10.1016/J.Cub.2012.03.052  0.444
2012 Sarangapani K, Akiyoshi B, Arellano-Santoyo H, Driver J, Duggan N, Powers A, Biggins S, Asbury C. Biophysical Study of Native Yeast Kinetochores Indicates Distinct Roles for Phospho-Regulation of Core Microtubule-Binding Subcomplexes Biophysical Journal. 102: 700a-701a. DOI: 10.1016/J.Bpj.2011.11.3803  0.341
2012 Asbury CL, Sarangapani KK, Akiyoshi B, Duggan N, Driver JW, Arellano-Santoyo H, Powers AF, Biggins S. How Kinetochores Promote Accuracy in Mitosis: Tension, Phosphoregulation, and the Chinese ‘Finger Trap’ Effect Biophysical Journal. 102: 222a. DOI: 10.1016/J.Bpj.2011.11.1219  0.343
2010 Akiyoshi B, Sarangapani KK, Powers AF, Nelson CR, Reichow SL, Arellano-Santoyo H, Gonen T, Ranish JA, Asbury CL, Biggins S. Tension directly stabilizes reconstituted kinetochore-microtubule attachments. Nature. 468: 576-9. PMID 21107429 DOI: 10.1038/Nature09594  0.326
2010 Akiyoshi B, Biggins S. Cdc14-dependent dephosphorylation of a kinetochore protein prior to anaphase in Saccharomyces cerevisiae Genetics. 186: 1487-1491. PMID 20923974 DOI: 10.1534/Genetics.110.123653  0.392
2009 Akiyoshi B, Nelson CR, Ranish JA, Biggins S. Quantitative proteomic analysis of purified yeast kinetochores identifies a PP1 regulatory subunit Genes and Development. 23: 2887-2899. PMID 19948764 DOI: 10.1101/Gad.1865909  0.403
2009 Akiyoshi B, Nelson CR, Ranish JA, Biggins S. Analysis of Ipl1-mediated phosphorylation of the Ndc80 kinetochore protein in Saccharomyces cerevisiae Genetics. 183: 1591-1595. PMID 19822728 DOI: 10.1534/Genetics.109.109041  0.32
2009 Ng TM, Waples WG, Lavoie BD, Biggins S. Pericentromeric sister chromatid cohesion promotes kinetochore biorientation. Molecular Biology of the Cell. 20: 3818-27. PMID 19605555 DOI: 10.1091/Mbc.E09-04-0330  0.432
2009 Pinsky BA, Nelson CR, Biggins S. Protein Phosphatase 1 Regulates Exit from the Spindle Checkpoint in Budding Yeast Current Biology. 19: 1182-1187. PMID 19592248 DOI: 10.1016/J.Cub.2009.06.043  0.41
2007 Kotwaliwale CV, Frei SB, Stern BM, Biggins S. A Pathway Containing the Ipl1/Aurora Protein Kinase and the Spindle Midzone Protein Ase1 Regulates Yeast Spindle Assembly Developmental Cell. 13: 433-445. PMID 17765685 DOI: 10.1016/J.Devcel.2007.07.003  0.449
2007 Collins KA, Camahort R, Seidel C, Gerton JL, Biggins S. The overexpression of a Saccharomyces cerevisiae centromeric histone H3 variant mutant protein leads to a defect in kinetochore biorientation Genetics. 175: 513-525. PMID 17151247 DOI: 10.1534/Genetics.106.064410  0.376
2007 Biggins S, Kotwaliwale C, Pinsky B, Buvelot S. The Ipl1/Aurora Protein Kinase and Glc7 Protein Phosphatase Regulate The Metaphase to Anaphase Transition The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A93-A  0.304
2006 Norden C, Mendoza M, Dobbelaere J, Kotwaliwale CV, Biggins S, Barral Y. The NoCut Pathway Links Completion of Cytokinesis to Spindle Midzone Function to Prevent Chromosome Breakage Cell. 125: 85-98. PMID 16615892 DOI: 10.1016/J.Cell.2006.01.045  0.314
2006 Pinsky BA, Kotwaliwale CV, Tatsutani SY, Breed CA, Biggins S. Glc7/protein phosphatase 1 regulatory subunits can oppose the Ipl1/Aurora protein kinase by redistributing Glc7 Molecular and Cellular Biology. 26: 2648-2660. PMID 16537909 DOI: 10.1128/Mcb.26.7.2648-2660.2006  0.402
2006 Pinsky BA, Kung C, Shokat KM, Biggins S. The Ipl1-Aurora protein kinase activates the spindle checkpoint by creating unattached kinetochores. Nature Cell Biology. 8: 78-83. PMID 16327780 DOI: 10.1038/Ncb1341  0.401
2005 Collins KA, Castillo AR, Tatsutani SY, Biggins S. De novo kinetochore assembly requires the centromeric histone H3 variant. Molecular Biology of the Cell. 16: 5649-60. PMID 16207811 DOI: 10.1091/Mbc.E05-08-0771  0.347
2004 Collins KA, Furuyama S, Biggins S. Proteolysis contributes to the exclusive centromere localization of the yeast Cse4/CENP-A histone H3 variant. Current Biology : Cb. 14: 1968-72. PMID 15530401 DOI: 10.1016/J.Cub.2004.10.024  0.41
2004 Biggins S. Correcting SYNful attachments. Nature Cell Biology. 6: 181-3. PMID 15039786 DOI: 10.1038/Ncb0304-181  0.309
2003 Pinsky BA, Tatsutani SY, Collins KA, Biggins S. An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Developmental Cell. 5: 735-45. PMID 14602074 DOI: 10.1016/S1534-5807(03)00322-8  0.455
2003 Buvelot S, Tatsutani SY, Vermaak D, Biggins S. The budding yeast Ipl1/Aurora protein kinase regulates mitotic spindle disassembly. The Journal of Cell Biology. 160: 329-39. PMID 12566427 DOI: 10.1083/Jcb.200209018  0.421
2002 Bhalla N, Biggins S, Murray AW. Mutation of YCS4, a budding yeast condensin subunit, affects mitotic and nonmitotic chromosome behavior. Molecular Biology of the Cell. 13: 632-45. PMID 11854418 DOI: 10.1091/Mbc.01-05-0264  0.376
2001 Biggins S, Murray AW. The budding yeast protein kinase Ipl1/Aurora allows the absence of tension to activate the spindle checkpoint. Genes & Development. 15: 3118-29. PMID 11731476 DOI: 10.1101/Gad.934801  0.41
2001 Biggins S, Bhalla N, Chang A, Smith DL, Murray AW. Genes involved in sister chromatid separation and segregation in the budding yeast Saccharomyces cerevisiae. Genetics. 159: 453-70. PMID 11606525  0.341
1999 Biggins S, Murray AW. Sister chromatid cohesion in mitosis. Current Opinion in Genetics & Development. 9: 230-6. PMID 10322145 DOI: 10.1016/S0959-437X(99)80034-3  0.357
1999 Biggins S, Severin FF, Bhalla N, Sassoon I, Hyman AA, Murray AW. The conserved protein kinase Ipl1 regulates microtubule binding to kinetochores in budding yeast. Genes & Development. 13: 532-44. PMID 10072382 DOI: 10.1101/Gad.13.5.532  0.445
1998 Biggins S, Murray AW. Sister chromatid cohesion in mitosis. Current Opinion in Cell Biology. 10: 769-75. PMID 9914173 DOI: 10.1016/S0955-0674(98)80120-8  0.383
1998 Sullivan DS, Biggins S, Rose MD. The yeast centrin, cdc31p, and the interacting protein kinase, Kic1p, are required for cell integrity. The Journal of Cell Biology. 143: 751-65. PMID 9813095 DOI: 10.1083/Jcb.143.3.751  0.572
1996 Biggins S, Ivanovska I, Rose MD. Yeast ubiquitin-like genes are involved in duplication of the microtubule organizing center. The Journal of Cell Biology. 133: 1331-46. PMID 8682868 DOI: 10.1083/Jcb.133.6.1331  0.52
1994 Biggins S, Rose MD. Direct interaction between yeast spindle pole body components: Kar1p is required for Cdc31p localization to the spindle pole body. The Journal of Cell Biology. 125: 843-52. PMID 8188750 DOI: 10.1083/Jcb.125.4.843  0.587
1993 Rose MD, Biggins S, Satterwhite LL. Unravelling the tangled web at the microtubule-organizing center. Current Opinion in Cell Biology. 5: 105-15. PMID 8448021 DOI: 10.1016/S0955-0674(05)80015-8  0.505
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