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Susan Gasser, Ph.D. - Publications

Affiliations: 
1986-2001 Swiss Institute for Experimental Cancer Research, Lausanne, VD, Switzerland 
 2001-2004 Molecular Biology Université de Genève, Genève, Genève, Switzerland 
 2004- Friedrich Miescher Institute for Biomedical Research, Basel, Basel-Stadt, Switzerland 
 2005- Molecular Biology Universität Basel, Basel, Basel-Stadt, Switzerland 
Website:
https://www.fmi.ch/research/groupleader/website/gasserlab/susangasser.php
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162 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Gasser SM, Stutz F. SUMO in the regulation of DNA repair and transcription at nuclear pores. Febs Letters. PMID 37805446 DOI: 10.1002/1873-3468.14751  0.441
2023 Gasser SM. Transient chromatin compaction in fork restart. Nature Cell Biology. PMID 37414848 DOI: 10.1038/s41556-023-01181-1  0.313
2021 Hurst V, Challa K, Jonas F, Forey R, Sack R, Seebacher J, Schmid CD, Barkai N, Shimada K, Gasser SM, Poli J. A regulatory phosphorylation site on Mec1 controls chromatin occupancy of RNA polymerases during replication stress. The Embo Journal. e108439. PMID 34569643 DOI: 10.15252/embj.2021108439  0.328
2021 Challa K, Seebacher J, Gasser SM. Sucrose gradient chromatin enrichment for quantitative proteomics analysis in budding yeast. Star Protocols. 2: 100825. PMID 34568845 DOI: 10.1016/j.xpro.2021.100825  0.323
2021 Hurst V, Challa K, Shimada K, Gasser SM. Cytoskeleton integrity influences XRCC1 and PCNA dynamics at DNA damage. Molecular Biology of the Cell. mbcE20100680. PMID 34379448 DOI: 10.1091/mbc.E20-10-0680  0.351
2021 Shimada K, Tsai-Pflugfelder M, Vijeh Motlagh ND, Delgoshaie N, Fuchs J, Gut H, Gasser SM. The stabilized Pol31-Pol3 interface counteracts Pol32 ablation with differential effects on repair. Life Science Alliance. 4. PMID 34226278 DOI: 10.26508/lsa.202101138  0.418
2021 Fuchs J, Cheblal A, Gasser SM. Underappreciated Roles of DNA Polymerase δ in Replication Stress Survival. Trends in Genetics : Tig. PMID 33608117 DOI: 10.1016/j.tig.2020.12.003  0.403
2021 Challa K, Schmid CD, Kitagawa S, Cheblal A, Iesmantavicius V, Seeber A, Amitai A, Seebacher J, Hauer MH, Shimada K, Gasser SM. Damage-induced chromatome dynamics link Ubiquitin ligase and proteasome recruitment to histone loss and efficient DNA repair. Molecular Cell. PMID 33529595 DOI: 10.1016/j.molcel.2020.12.021  0.799
2020 Padeken J, Methot S, Zeller P, Delaney CE, Kalck V, Gasser SM. Argonaute NRDE-3 and MBT domain protein LIN-61 redundantly recruit an H3K9me3 HMT to prevent embryonic lethality and transposon expression. Genes & Development. PMID 33303642 DOI: 10.1101/gad.344234.120  0.305
2020 Forey R, Barthe A, Tittel-Elmer M, Wery M, Barrault MB, Ducrot C, Seeber A, Krietenstein N, Szachnowski U, Skrzypczak M, Ginalski K, Rowicka M, Cobb JA, Rando OJ, Soutourina J, ... ... Gasser SM, et al. A Role for the Mre11-Rad50-Xrs2 Complex in Gene Expression and Chromosome Organization. Molecular Cell. PMID 33278361 DOI: 10.1016/j.molcel.2020.11.010  0.78
2020 Cheblal A, Challa K, Seeber A, Shimada K, Yoshida H, Ferreira HC, Amitai A, Gasser SM. DNA Damage-Induced Nucleosome Depletion Enhances Homology Search Independently of Local Break Movement. Molecular Cell. PMID 32970994 DOI: 10.1016/j.molcel.2020.09.002  0.765
2020 Falquet B, Ölmezer G, Enkner F, Klein D, Challa K, Appanah R, Gasser SM, Rass U. Disease-associated DNA2 nuclease-helicase protects cells from lethal chromosome under-replication. Nucleic Acids Research. PMID 32544229 DOI: 10.1093/nar/gkaa524  0.472
2019 Sasanuma H, Sakurai HSM, Furihata Y, Challa K, Palmer L, Gasser SM, Shinohara M, Shinohara A. Srs2 helicase prevents the formation of toxic DNA damage during late prophase I of yeast meiosis. Chromosoma. PMID 31168653 DOI: 10.1007/s00412-019-00709-5  0.476
2019 Cabianca DS, Muñoz-Jiménez C, Kalck V, Gaidatzis D, Padeken J, Seeber A, Askjaer P, Gasser SM. Active chromatin marks drive spatial sequestration of heterochromatin in C. elegans nuclei. Nature. 569: 734-739. PMID 31118512 DOI: 10.1038/S41586-019-1243-Y  0.742
2019 Hurst V, Shimada K, Gasser SM. Nuclear Actin and Actin-Binding Proteins in DNA Repair. Trends in Cell Biology. PMID 30954333 DOI: 10.1016/j.tcb.2019.02.010  0.41
2019 Gasser S. Once and Only Once. Cell. 177: 495-498. PMID 30952443 DOI: 10.1016/J.Cell.2019.03.034  0.404
2019 Hurst V, Gasser SM. The study of protein recruitment to laser-induced DNA lesions can be distorted by photoconversion of the DNA binding dye Hoechst. F1000research. 8: 104. PMID 30828443 DOI: 10.12688/f1000research.17865.2  0.353
2019 Padeken J, Zeller P, Towbin B, Katic I, Kalck V, Methot SP, Gasser SM. Synergistic lethality between BRCA1 and H3K9me2 loss reflects satellite derepression. Genes & Development. PMID 30804228 DOI: 10.1101/gad.322495.118  0.379
2019 Hurst V, Gasser SM. The study of protein recruitment to UV-induced DNA lesions can be distorted by photoconversion of DNA dyes like Hoechst or DAPI F1000research. 8: 104. DOI: 10.12688/f1000research.17865.1  0.396
2018 Seeber A, Hauer MH, Gasser SM. Chromosome Dynamics in Response to DNA Damage. Annual Review of Genetics. PMID 30208290 DOI: 10.1146/Annurev-Genet-120417-031334  0.787
2018 Marcomini I, Shimada K, Delgoshaie N, Yamamoto I, Seeber A, Cheblal A, Horigome C, Naumann U, Gasser SM. Asymmetric Processing of DNA Ends at a Double-Strand Break Leads to Unconstrained Dynamics and Ectopic Translocation. Cell Reports. 24: 2614-2628.e4. PMID 30184497 DOI: 10.1016/J.Celrep.2018.07.102  0.773
2018 Ahringer J, Gasser SM. Repressive Chromatin in Caenorhabditis elegans: Establishment, Composition, and Function. Genetics. 208: 491-511. PMID 29378810 DOI: 10.1534/genetics.117.300386  0.327
2017 Hauer MH, Gasser SM. Chromatin and nucleosome dynamics in DNA damage and repair. Genes & Development. 31: 2204-2221. PMID 29284710 DOI: 10.1101/gad.307702.117  0.437
2017 Zeller P, Gasser SM. The Importance of Satellite Sequence Repression for Genome Stability. Cold Spring Harbor Symposia On Quantitative Biology. 82: 15-24. PMID 29133300 DOI: 10.1101/sqb.2017.82.033662  0.35
2017 Deshpande I, Seeber A, Shimada K, Keusch JJ, Gut H, Gasser SM. Structural Basis of Mec1-Ddc2-RPA Assembly and Activation on Single-Stranded DNA at Sites of Damage. Molecular Cell. PMID 29033322 DOI: 10.1016/J.Molcel.2017.09.019  0.773
2017 Poli J, Gasser SM, Papamichos-Chronakis M. The INO80 remodeller in transcription, replication and repair. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 372. PMID 28847827 DOI: 10.1098/rstb.2016.0290  0.496
2017 Jeggo PA, Downs JA, Gasser SM. Chromatin modifiers and remodellers in DNA repair and signalling. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 372. PMID 28847816 DOI: 10.1098/Rstb.2016.0279  0.481
2017 Shimada K, Gasser SM. A game of musical chairs: Pro- and anti-resection factors compete for TOPBP1 binding after DNA damage. The Journal of Cell Biology. PMID 28235945 DOI: 10.1083/jcb.201701038  0.364
2017 Amitai A, Seeber A, Gasser SM, Holcman D. Visualization of Chromatin Decompaction and Break Site Extrusion as Predicted by Statistical Polymer Modeling of Single-Locus Trajectories. Cell Reports. 18: 1200-1214. PMID 28147275 DOI: 10.1016/J.Celrep.2017.01.018  0.748
2017 Hauer MH, Seeber A, Singh V, Thierry R, Sack R, Amitai A, Kryzhanovska M, Eglinger J, Holcman D, Owen-Hughes T, Gasser SM. Histone degradation in response to DNA damage enhances chromatin dynamics and recombination rates. Nature Structural & Molecular Biology. PMID 28067915 DOI: 10.1038/Nsmb.3347  0.793
2016 Gasser SM. Selfish DNA and Epigenetic Repression Revisited. Genetics. 204: 837-839. PMID 28114097 DOI: 10.1534/genetics.116.196287  0.422
2016 Seeber A, Hegnauer AM, Hustedt N, Deshpande I, Poli J, Eglinger J, Pasero P, Gut H, Shinohara M, Hopfner KP, Shimada K, Gasser SM. RPA Mediates Recruitment of MRX to Forks and Double-Strand Breaks to Hold Sister Chromatids Together. Molecular Cell. PMID 27889450 DOI: 10.1016/J.Molcel.2016.10.032  0.755
2016 Seeber A, Gasser SM. Chromatin organization and dynamics in double-strand break repair. Current Opinion in Genetics & Development. 43: 9-16. PMID 27810555 DOI: 10.1016/J.Gde.2016.10.005  0.792
2016 Zeller P, Padeken J, van Schendel R, Kalck V, Tijsterman M, Gasser SM. Histone H3K9 methylation is dispensable for Caenorhabditis elegans development but suppresses RNA:DNA hybrid-associated repeat instability. Nature Genetics. 48: 1385-1395. PMID 27668659 DOI: 10.1038/ng.3672  0.385
2016 Gonzalez-Sandoval A, Gasser SM. On TADs and LADs: Spatial Control Over Gene Expression. Trends in Genetics : Tig. PMID 27312344 DOI: 10.1016/j.tig.2016.05.004  0.36
2016 Gasser SM. Nuclear Architecture: Past and Future Tense. Trends in Cell Biology. PMID 27177990 DOI: 10.1016/j.tcb.2016.04.011  0.359
2016 Horigome C, Bustard DE, Marcomini I, Delgoshaie N, Tsai-Pflugfelder M, Cobb JA, Gasser SM. PolySUMOylation by Siz2 and Mms21 triggers relocation of DNA breaks to nuclear pores through the Slx5/Slx8 STUbL. Genes & Development. PMID 27056668 DOI: 10.1101/gad.277665.116  0.437
2016 Iwasaki D, Hayashihara K, Shima H, Higashide M, Terasawa M, Gasser SM, Shinohara M. The MRX Complex Ensures NHEJ Fidelity through Multiple Pathways Including Xrs2-FHA-Dependent Tel1 Activation. Plos Genetics. 12: e1005942. PMID 26990569 DOI: 10.1371/journal.pgen.1005942  0.404
2016 Poli J, Gerhold CB, Tosi A, Hustedt N, Seeber A, Sack R, Herzog F, Pasero P, Shimada K, Hopfner KP, Gasser SM. Mec1, INO80, and the PAF1 complex cooperate to limit transcription replication conflicts through RNAPII removal during replication stress. Genes & Development. 30: 337-54. PMID 26798134 DOI: 10.1101/Gad.273813.115  0.753
2016 Harr JC, Gonzalez-Sandoval A, Gasser SM. Histones and histone modifications in perinuclear chromatin anchoring: from yeast to man. Embo Reports. 17: 139-55. PMID 26792937 DOI: 10.15252/embr.201541809  0.314
2015 Marcomini I, Gasser SM. Nuclear organization in DNA end processing: Telomeres vs double-strand breaks. Dna Repair. 32: 134-40. PMID 26004856 DOI: 10.1016/j.dnarep.2015.04.024  0.442
2015 Su XA, Dion V, Gasser SM, Freudenreich CH. Regulation of recombination at yeast nuclear pores controls repair and triplet repeat stability. Genes & Development. 29: 1006-17. PMID 25940904 DOI: 10.1101/gad.256404.114  0.462
2015 Horigome C, Dion V, Seeber A, Gehlen LR, Gasser SM. Visualizing the spatiotemporal dynamics of DNA damage in budding yeast. Methods in Molecular Biology (Clifton, N.J.). 1292: 77-96. PMID 25804749 DOI: 10.1007/978-1-4939-2522-3_6  0.773
2015 Hustedt N, Seeber A, Sack R, Tsai-Pflugfelder M, Bhullar B, Vlaming H, van Leeuwen F, Guénolé A, van Attikum H, Srivas R, Ideker T, Shimada K, Gasser SM. Yeast PP4 interacts with ATR homolog Ddc2-Mec1 and regulates checkpoint signaling. Molecular Cell. 57: 273-89. PMID 25533186 DOI: 10.1016/J.Molcel.2014.11.016  0.75
2015 Gerhold CB, Hauer MH, Gasser SM. INO80-C and SWR-C: guardians of the genome. Journal of Molecular Biology. 427: 637-51. PMID 25451604 DOI: 10.1016/j.jmb.2014.10.015  0.427
2014 Gerhold CB, Gasser SM. INO80 and SWR complexes: relating structure to function in chromatin remodeling. Trends in Cell Biology. 24: 619-31. PMID 25088669 DOI: 10.1016/j.tcb.2014.06.004  0.369
2014 Horigome C, Oma Y, Konishi T, Schmid R, Marcomini I, Hauer MH, Dion V, Harata M, Gasser SM. SWR1 and INO80 chromatin remodelers contribute to DNA double-strand break perinuclear anchorage site choice. Molecular Cell. 55: 626-39. PMID 25066231 DOI: 10.1016/j.molcel.2014.06.027  0.38
2014 Weisman R, Cohen A, Gasser SM. TORC2-a new player in genome stability. Embo Molecular Medicine. 6: 995-1002. PMID 24992933 DOI: 10.15252/Emmm.201403959  0.31
2014 Seeber A, Dion V, Gasser SM. Remodelers move chromatin in response to DNA damage. Cell Cycle (Georgetown, Tex.). 13: 877-8. PMID 24552812 DOI: 10.4161/Cc.28200  0.806
2013 Hustedt N, Gasser SM, Shimada K. Replication checkpoint: tuning and coordination of replication forks in s phase. Genes. 4: 388-434. PMID 24705211 DOI: 10.3390/genes4030388  0.426
2013 Ferreira HC, Towbin BD, Jegou T, Gasser SM. The shelterin protein POT-1 anchors Caenorhabditis elegans telomeres through SUN-1 at the nuclear periphery. The Journal of Cell Biology. 203: 727-35. PMID 24297748 DOI: 10.1083/jcb.201307181  0.347
2013 Nielsen I, Bentsen IB, Andersen AH, Gasser SM, Bjergbaek L. A Rad53 independent function of Rad9 becomes crucial for genome maintenance in the absence of the Recq helicase Sgs1. Plos One. 8: e81015. PMID 24278365 DOI: 10.1371/journal.pone.0081015  0.404
2013 Shimada K, Filipuzzi I, Stahl M, Helliwell SB, Studer C, Hoepfner D, Seeber A, Loewith R, Movva NR, Gasser SM. TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks. Molecular Cell. 51: 829-39. PMID 24035500 DOI: 10.1016/J.Molcel.2013.08.019  0.752
2013 Seeber A, Dion V, Gasser SM. Checkpoint kinases and the INO80 nucleosome remodeling complex enhance global chromatin mobility in response to DNA damage. Genes & Development. 27: 1999-2008. PMID 24029917 DOI: 10.1101/Gad.222992.113  0.804
2013 Dion V, Kalck V, Seeber A, Schleker T, Gasser SM. Cohesin and the nucleolus constrain the mobility of spontaneous repair foci. Embo Reports. 14: 984-91. PMID 24018421 DOI: 10.1038/Embor.2013.142  0.77
2013 Kueng S, Oppikofer M, Gasser SM. SIR proteins and the assembly of silent chromatin in budding yeast. Annual Review of Genetics. 47: 275-306. PMID 24016189 DOI: 10.1146/annurev-genet-021313-173730  0.33
2013 Oppikofer M, Kueng S, Gasser SM. SIR-nucleosome interactions: structure-function relationships in yeast silent chromatin. Gene. 527: 10-25. PMID 23791651 DOI: 10.1016/j.gene.2013.05.088  0.341
2013 Gonzalez-Sandoval A, Towbin BD, Gasser SM. The formation and sequestration of heterochromatin during development: delivered on 7 September 2012 at the 37th FEBS Congress in Sevilla, Spain. The Febs Journal. 280: 3212-9. PMID 23648132 DOI: 10.1111/febs.12319  0.323
2013 Dion V, Gasser SM. Chromatin movement in the maintenance of genome stability. Cell. 152: 1355-64. PMID 23498942 DOI: 10.1016/j.cell.2013.02.010  0.395
2013 Seeber A, Hauer M, Gasser SM. Nucleosome remodelers in double-strand break repair. Current Opinion in Genetics & Development. 23: 174-84. PMID 23352131 DOI: 10.1016/J.Gde.2012.12.008  0.77
2012 Taddei A, Gasser SM. Structure and function in the budding yeast nucleus. Genetics. 192: 107-29. PMID 22964839 DOI: 10.1534/genetics.112.140608  0.315
2012 Hegnauer AM, Hustedt N, Shimada K, Pike BL, Vogel M, Amsler P, Rubin SM, van Leeuwen F, Guénolé A, van Attikum H, Thomä NH, Gasser SM. An N-terminal acidic region of Sgs1 interacts with Rpa70 and recruits Rad53 kinase to stalled forks. The Embo Journal. 31: 3768-83. PMID 22820947 DOI: 10.1038/emboj.2012.195  0.346
2012 Kueng S, Tsai-Pflugfelder M, Oppikofer M, Ferreira HC, Roberts E, Tsai C, Roloff TC, Sack R, Gasser SM. Regulating repression: roles for the sir4 N-terminus in linker DNA protection and stabilization of epigenetic states. Plos Genetics. 8: e1002727. PMID 22654676 DOI: 10.1371/journal.pgen.1002727  0.356
2012 Shimada K, Gasser SM. DNA replication: Pif1 pulls the plug on stalled replication forks. Current Biology : Cb. 22: R404-5. PMID 22625857 DOI: 10.1016/j.cub.2012.04.015  0.372
2012 Dion V, Kalck V, Horigome C, Towbin BD, Gasser SM. Increased mobility of double-strand breaks requires Mec1, Rad9 and the homologous recombination machinery. Nature Cell Biology. 14: 502-9. PMID 22484486 DOI: 10.1038/ncb2465  0.493
2012 Neumann FR, Dion V, Gehlen LR, Tsai-Pflugfelder M, Schmid R, Taddei A, Gasser SM. Targeted INO80 enhances subnuclear chromatin movement and ectopic homologous recombination. Genes & Development. 26: 369-83. PMID 22345518 DOI: 10.1101/gad.176156.111  0.383
2011 Oppikofer M, Kueng S, Martino F, Soeroes S, Hancock SM, Chin JW, Fischle W, Gasser SM. A dual role of H4K16 acetylation in the establishment of yeast silent chromatin. The Embo Journal. 30: 2610-21. PMID 21666601 DOI: 10.1038/Emboj.2011.170  0.322
2011 Meister P, Mango SE, Gasser SM. Locking the genome: nuclear organization and cell fate. Current Opinion in Genetics & Development. 21: 167-74. PMID 21345665 DOI: 10.1016/j.gde.2011.01.023  0.302
2011 Nagai S, Davoodi N, Gasser SM. Nuclear organization in genome stability: SUMO connections. Cell Research. 21: 474-85. PMID 21321608 DOI: 10.1038/cr.2011.31  0.386
2011 Kitada T, Schleker T, Sperling AS, Xie W, Gasser SM, Grunstein M. γH2A is a component of yeast heterochromatin required for telomere elongation. Cell Cycle (Georgetown, Tex.). 10: 293-300. PMID 21212735 DOI: 10.4161/Cc.10.2.14536  0.322
2011 Gehlen LR, Gasser SM, Dion V. How Broken DNA Finds Its Template for Repair: A Computational Approach Progress of Theoretical Physics Supplement. 191: 20-29. DOI: 10.1143/PTPS.191.20  0.347
2010 Nagai S, Heun P, Gasser SM. Roles for nuclear organization in the maintenance of genome stability. Epigenomics. 2: 289-305. PMID 22121875 DOI: 10.2217/epi.09.49  0.406
2010 Meister P, Gehlen LR, Varela E, Kalck V, Gasser SM. Visualizing yeast chromosomes and nuclear architecture. Methods in Enzymology. 470: 535-67. PMID 20946824 DOI: 10.1016/S0076-6879(10)70021-5  0.363
2010 Taddei A, Schober H, Gasser SM. The budding yeast nucleus. Cold Spring Harbor Perspectives in Biology. 2: a000612. PMID 20554704 DOI: 10.1101/cshperspect.a000612  0.417
2010 Dion V, Shimada K, Gasser SM. Actin-related proteins in the nucleus: life beyond chromatin remodelers. Current Opinion in Cell Biology. 22: 383-91. PMID 20303249 DOI: 10.1016/j.ceb.2010.02.006  0.452
2009 Bühler M, Gasser SM. Silent chromatin at the middle and ends: lessons from yeasts. The Embo Journal. 28: 2149-61. PMID 19629038 DOI: 10.1038/emboj.2009.185  0.41
2009 Schleker T, Nagai S, Gasser SM. Posttranslational modifications of repair factors and histones in the cellular response to stalled replication forks. Dna Repair. 8: 1089-100. PMID 19482523 DOI: 10.1016/j.dnarep.2009.04.010  0.456
2009 Schober H, Ferreira H, Kalck V, Gehlen LR, Gasser SM. Yeast telomerase and the SUN domain protein Mps3 anchor telomeres and repress subtelomeric recombination. Genes & Development. 23: 928-38. PMID 19390087 DOI: 10.1101/gad.1787509  0.375
2009 van Attikum H, Gasser SM. Crosstalk between histone modifications during the DNA damage response. Trends in Cell Biology. 19: 207-17. PMID 19342239 DOI: 10.1016/j.tcb.2009.03.001  0.516
2009 Towbin BD, Meister P, Gasser SM. The nuclear envelope--a scaffold for silencing? Current Opinion in Genetics & Development. 19: 180-6. PMID 19303765 DOI: 10.1016/j.gde.2009.01.006  0.313
2009 Friedel AM, Pike BL, Gasser SM. ATR/Mec1: coordinating fork stability and repair. Current Opinion in Cell Biology. 21: 237-44. PMID 19230642 DOI: 10.1016/j.ceb.2009.01.017  0.44
2009 Martino F, Kueng S, Robinson P, Tsai-Pflugfelder M, van Leeuwen F, Ziegler M, Cubizolles F, Cockell MM, Rhodes D, Gasser SM. Reconstitution of yeast silent chromatin: multiple contact sites and O-AADPR binding load SIR complexes onto nucleosomes in vitro. Molecular Cell. 33: 323-34. PMID 19217406 DOI: 10.1016/J.Molcel.2009.01.009  0.344
2009 Taddei A, Van Houwe G, Nagai S, Erb I, van Nimwegen E, Gasser SM. The functional importance of telomere clustering: global changes in gene expression result from SIR factor dispersion. Genome Research. 19: 611-25. PMID 19179643 DOI: 10.1101/gr.083881.108  0.311
2008 Nagai S, Dubrana K, Tsai-Pflugfelder M, Davidson MB, Roberts TM, Brown GW, Varela E, Hediger F, Gasser SM, Krogan NJ. Functional targeting of DNA damage to a nuclear pore-associated SUMO-dependent ubiquitin ligase. Science (New York, N.Y.). 322: 597-602. PMID 18948542 DOI: 10.1126/Science.1162790  0.464
2008 Shimada K, Oma Y, Schleker T, Kugou K, Ohta K, Harata M, Gasser SM. Ino80 chromatin remodeling complex promotes recovery of stalled replication forks. Current Biology : Cb. 18: 566-75. PMID 18406137 DOI: 10.1016/j.cub.2008.03.049  0.491
2007 Dubrana K, van Attikum H, Hediger F, Gasser SM. The processing of double-strand breaks and binding of single-strand-binding proteins RPA and Rad51 modulate the formation of ATR-kinase foci in yeast. Journal of Cell Science. 120: 4209-20. PMID 18003698 DOI: 10.1242/jcs.018366  0.387
2007 van Attikum H, Fritsch O, Gasser SM. Distinct roles for SWR1 and INO80 chromatin remodeling complexes at chromosomal double-strand breaks. The Embo Journal. 26: 4113-25. PMID 17762868 DOI: 10.1038/sj.emboj.7601835  0.416
2007 Meister P, Taddei A, Ponti A, Baldacci G, Gasser SM. Replication foci dynamics: replication patterns are modulated by S-phase checkpoint kinases in fission yeast. The Embo Journal. 26: 1315-26. PMID 17304223 DOI: 10.1038/sj.emboj.7601538  0.331
2007 Shimada K, Gasser SM. The origin recognition complex functions in sister-chromatid cohesion in Saccharomyces cerevisiae. Cell. 128: 85-99. PMID 17218257 DOI: 10.1016/j.cell.2006.11.045  0.368
2006 Meister P, Taddei A, Gasser SM. In and out of the replication factory. Cell. 125: 1233-5. PMID 16814710 DOI: 10.1016/j.cell.2006.06.014  0.328
2006 Taddei A, Gasser SM. Repairing subtelomeric DSBs at the nuclear periphery. Trends in Cell Biology. 16: 225-8. PMID 16621562 DOI: 10.1016/j.tcb.2006.03.005  0.404
2006 Cubizolles F, Martino F, Perrod S, Gasser SM. A homotrimer-heterotrimer switch in Sir2 structure differentiates rDNA and telomeric silencing. Molecular Cell. 21: 825-36. PMID 16543151 DOI: 10.1016/j.molcel.2006.02.006  0.301
2006 Rosa A, Maddocks JH, Neumann FR, Gasser SM, Stasiak A. Measuring limits of telomere movement on nuclear envelope. Biophysical Journal. 90: L24-6. PMID 16339888 DOI: 10.1529/biophysj.105.077974  0.314
2005 Cobb JA, Schleker T, Rojas V, Bjergbaek L, Tercero JA, Gasser SM. Replisome instability, fork collapse, and gross chromosomal rearrangements arise synergistically from Mec1 kinase and RecQ helicase mutations. Genes & Development. 19: 3055-69. PMID 16357221 DOI: 10.1101/gad.361805  0.38
2005 van Attikum H, Gasser SM. The histone code at DNA breaks: a guide to repair? Nature Reviews. Molecular Cell Biology. 6: 757-65. PMID 16167054 DOI: 10.1038/nrm1737  0.483
2005 van Attikum H, Gasser SM. ATP-dependent chromatin remodeling and DNA double-strand break repair. Cell Cycle (Georgetown, Tex.). 4: 1011-4. PMID 16082209 DOI: 10.4161/cc.4.8.1887  0.513
2005 Taddei A, Gartenberg MR, Neumann FR, Hediger F, Gasser SM. Multiple pathways tether telomeres and silent chromatin at the nuclear periphery: functional implications for sir-mediated repression. Novartis Foundation Symposium. 264: 140-56; discussion 1. PMID 15773752 DOI: 10.1002/0470093765.Ch10  0.368
2005 Meister P, Taddei A, Vernis L, Poidevin M, Gasser SM, Baldacci G. Temporal separation of replication and recombination requires the intra-S checkpoint. The Journal of Cell Biology. 168: 537-44. PMID 15716375 DOI: 10.1083/jcb.200410006  0.396
2005 Bjergbaek L, Cobb JA, Tsai-Pflugfelder M, Gasser SM. Mechanistically distinct roles for Sgs1p in checkpoint activation and replication fork maintenance. The Embo Journal. 24: 405-17. PMID 15616582 DOI: 10.1038/sj.emboj.7600511  0.357
2004 Gartenberg MR, Neumann FR, Laroche T, Blaszczyk M, Gasser SM. Sir-mediated repression can occur independently of chromosomal and subnuclear contexts. Cell. 119: 955-67. PMID 15620354 DOI: 10.1016/J.Cell.2004.11.008  0.402
2004 van Attikum H, Fritsch O, Hohn B, Gasser SM. Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair. Cell. 119: 777-88. PMID 15607975 DOI: 10.1016/J.Cell.2004.11.033  0.494
2004 Taddei A, Hediger F, Neumann FR, Gasser SM. The function of nuclear architecture: a genetic approach. Annual Review of Genetics. 38: 305-45. PMID 15568979 DOI: 10.1146/annurev.genet.37.110801.142705  0.342
2004 Bystricky K, Heun P, Gehlen L, Langowski J, Gasser SM. Long-range compaction and flexibility of interphase chromatin in budding yeast analyzed by high-resolution imaging techniques Proceedings of the National Academy of Sciences of the United States of America. 101: 16495-16500. PMID 15545610 DOI: 10.1073/pnas.0402766101  0.306
2004 Cobb JA, Shimada K, Gasser SM. Redundancy, insult-specific sensors and thresholds: unlocking the S-phase checkpoint response. Current Opinion in Genetics & Development. 14: 292-300. PMID 15172673 DOI: 10.1016/j.gde.2004.04.001  0.396
2004 Taddei A, Hediger F, Neumann FR, Bauer C, Gasser SM. Separation of silencing from perinuclear anchoring functions in yeast Ku80, Sir4 and Esc1 proteins. The Embo Journal. 23: 1301-12. PMID 15014445 DOI: 10.1038/sj.emboj.7600144  0.322
2004 Gilson E, Laroche T, Gasser SM. Telomeres and the functional architecture of the nucleus. Trends in Cell Biology. 3: 128-34. PMID 14731767 DOI: 10.1016/0962-8924(93)90175-Z  0.432
2003 Perrod S, Gasser SM. Long-range silencing and position effects at telomeres and centromeres: parallels and differences. Cellular and Molecular Life Sciences : Cmls. 60: 2303-18. PMID 14625677 DOI: 10.1007/s00018-003-3246-x  0.479
2003 Khakhar RR, Cobb JA, Bjergbaek L, Hickson ID, Gasser SM. RecQ helicases: multiple roles in genome maintenance. Trends in Cell Biology. 13: 493-501. PMID 12946629 DOI: 10.1016/S0962-8924(03)00171-5  0.328
2003 Cobb JA, Bjergbaek L, Shimada K, Frei C, Gasser SM. DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1. The Embo Journal. 22: 4325-36. PMID 12912929 DOI: 10.1093/emboj/cdg391  0.465
2002 Shimada K, Pasero P, Gasser SM. ORC and the intra-S-phase checkpoint: a threshold regulates Rad53p activation in S phase. Genes & Development. 16: 3236-52. PMID 12502744 DOI: 10.1101/gad.239802  0.383
2002 Hediger F, Dubrana K, Gasser SM. Myosin-like proteins 1 and 2 are not required for silencing or telomere anchoring, but act in the Tel1 pathway of telomere length control. Journal of Structural Biology. 140: 79-91. PMID 12490156  0.315
2002 Bjergbaek L, Cobb JA, Gasser SM. RecQ helicases and genome stability: lessons from model organisms and human disease. Swiss Medical Weekly. 132: 433-42. PMID 12457301  0.435
2002 Duncker BP, Shimada K, Tsai-Pflugfelder M, Pasero P, Gasser SM. An N-terminal domain of Dbf4p mediates interaction with both origin recognition complex (ORC) and Rad53p and can deregulate late origin firing. Proceedings of the National Academy of Sciences of the United States of America. 99: 16087-92. PMID 12441400 DOI: 10.1073/pnas.252093999  0.321
2002 Cobb JA, Bjergbaek L, Gasser SM. RecQ helicases: at the heart of genetic stability. Febs Letters. 529: 43-8. PMID 12354611 DOI: 10.1016/S0014-5793(02)03269-6  0.325
2002 Pasero P, Gasser SM. In vitro DNA replication assays in yeast extracts. Methods in Enzymology. 351: 184-99. PMID 12073345 DOI: 10.1016/S0076-6879(02)51848-6  0.346
2001 Heun P, Laroche T, Shimada K, Furrer P, Gasser SM. Chromosome dynamics in the yeast interphase nucleus. Science (New York, N.Y.). 294: 2181-6. PMID 11739961 DOI: 10.1126/science.1065366  0.337
2001 Gasser SM, Cockell MM. The molecular biology of the SIR proteins. Gene. 279: 1-16. PMID 11722841 DOI: 10.1016/s0378-1119(01)00741-7  0.388
2001 Heun P, Taddei A, Gasser SM. From snapshots to moving pictures: new perspectives on nuclear organization. Trends in Cell Biology. 11: 519-25. PMID 11719059  0.32
2001 Dubrana K, Perrod S, Gasser SM. Turning telomeres off and on. Current Opinion in Cell Biology. 13: 281-9. PMID 11343898  0.36
2001 Heun P, Laroche T, Raghuraman MK, Gasser SM. The positioning and dynamics of origins of replication in the budding yeast nucleus. The Journal of Cell Biology. 152: 385-400. PMID 11266454 DOI: 10.1083/jcb.152.2.385  0.322
2001 Perrod S, Cockell MM, Laroche T, Renauld H, Ducrest AL, Bonnard C, Gasser SM. A cytosolic NAD-dependent deacetylase, Hst2p, can modulate nucleolar and telomeric silencing in yeast. The Embo Journal. 20: 197-209. PMID 11226170 DOI: 10.1093/emboj/20.1.197  0.307
2000 Frei C, Gasser SM. RecQ-like helicases: the DNA replication checkpoint connection. Journal of Cell Science. 113: 2641-6. PMID 10893179  0.381
2000 Laroche T, Martin SG, Tsai-Pflugfelder M, Gasser SM. The dynamics of yeast telomeres and silencing proteins through the cell cycle. Journal of Structural Biology. 129: 159-74. PMID 10806066 DOI: 10.1006/Jsbi.2000.4240  0.318
2000 Frei C, Gasser SM. The yeast Sgs1p helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase-specific foci. Genes & Development. 14: 81-96. PMID 10640278  0.418
1999 Pasero P, Duncker BP, Gasser SM. In vitro DNA replication in yeast nuclear extracts. Methods (San Diego, Calif.). 18: 368-76, 323. PMID 10454998 DOI: 10.1006/METH.1999.0794  0.414
1999 Martin SG, Laroche T, Suka N, Grunstein M, Gasser SM. Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast. Cell. 97: 621-33. PMID 10367891 DOI: 10.1016/S0092-8674(00)80773-4  0.481
1998 Akhmedov AT, Frei C, Tsai-Pflugfelder M, Kemper B, Gasser SM, Jessberger R. Structural maintenance of chromosomes protein C-terminal domains bind preferentially to DNA with secondary structure. The Journal of Biological Chemistry. 273: 24088-94. PMID 9727028 DOI: 10.1074/jbc.273.37.24088  0.438
1998 Cockell M, Renauld H, Watt P, Gasser SM. Sif2p interacts with Sir4p amino-terminal domain and antagonizes telomeric silencing in yeast. Current Biology : Cb. 8: 787-90. PMID 9651685 DOI: 10.1016/S0960-9822(98)70304-5  0.333
1998 Pasero P, Gasser SM. New systems for replicating DNA in vitro. Current Opinion in Cell Biology. 10: 304-10. PMID 9640529 DOI: 10.1016/S0955-0674(98)80004-5  0.418
1998 Laroche T, Martin SG, Gotta M, Gorham HC, Pryde FE, Louis EJ, Gasser SM. Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres. Current Biology : Cb. 8: 653-6. PMID 9635192 DOI: 10.1016/S0960-9822(98)70252-0  0.408
1998 Jessberger R, Frei C, Gasser SM. Chromosome dynamics: the SMC protein family. Current Opinion in Genetics & Development. 8: 254-9. PMID 9610418 DOI: 10.1016/S0959-437X(98)80149-4  0.344
1998 Gasser SM, Gotta M, Renauld H, Laroche T, Cockell M. Nuclear organization and silencing: trafficking of Sir proteins. Novartis Foundation Symposium. 214: 114-26; discussion 1. PMID 9601014 DOI: 10.1002/9780470515501.CH7  0.327
1998 Gasser SM, Paro R, Stewart F, Aasland R. The genetics of epigenetics. Cellular and Molecular Life Sciences : Cmls. 54: 1-5. PMID 9487382  0.35
1998 Pasero P, Heu P, Duncker B, Braguglia D, Gasser S. In vitro DNA synthesis: Subnuclear targeting of cell-cycle regulated kinases regulate ORC-dependent replication in isolated yeast nuclei Biology of the Cell. 90: 88-107. DOI: 10.1016/S0248-4900(98)80235-9  0.346
1998 Braguglia D, Heun P, Pasero P, Duncker B, Gasser S. Semi-conservative replication in yeast nuclear extracts requires Dna2 helicase and supercoiled template 1 1Edited by M. Yaniv Journal of Molecular Biology. 281: 631-649. DOI: 10.1006/JMBI.1998.1973  0.359
1997 Pasero P, Braguglia D, Gasser SM. ORC-dependent and origin-specific initiation of DNA replication at defined foci in isolated yeast nuclei. Genes & Development. 11: 1504-18. PMID 9203578 DOI: 10.1101/GAD.11.12.1504  0.398
1997 Gotta M, Gasser SM. Nuclear organization and transcriptional silencing in yeast. Experientia. 52: 1136-47. PMID 8988257 DOI: 10.1007/BF01952113  0.355
1996 Gotta M, Laroche T, Formenton A, Maillet L, Scherthan H, Gasser SM. The clustering of telomeres and colocalization with Rap1, Sir3, and Sir4 proteins in wild-type Saccharomyces cerevisiae. The Journal of Cell Biology. 134: 1349-63. PMID 8830766 DOI: 10.1083/Jcb.134.6.1349  0.382
1995 Grunstein M, Hecht A, Fisher-Adams G, Wan J, Mann RK, Strahl-Bolsinger S, Laroche T, Gasser S. The regulation of euchromatin and heterochromatin by histones in yeast. Journal of Cell Science. Supplement. 19: 29-36. PMID 8655644 DOI: 10.1242/Jcs.1995.Supplement_19.4  0.363
1995 Müller T, Gilson E, Schmidt R, Giraldo R, Sogo J, Gross H, Gasser SM. Imaging the asymmetrical DNA bend induced by repressor activator protein 1 with scanning tunneling microscopy. Journal of Structural Biology. 113: 1-12. PMID 7880649 DOI: 10.1006/JSBI.1994.1027  0.392
1995 Gilson E, Müller T, Sogo J, Laroche T, Gasser SM. RAP1 stimulates single- to double-strand association of yeast telomeric DNA: implications for telomere-telomere interactions. Nucleic Acids Research. 22: 5310-20. PMID 7816621 DOI: 10.1093/NAR/22.24.5310  0.426
1994 Dang Q, Alghisi GC, Gasser SM. Phosphorylation of the C-terminal domain of yeast topoisomerase II by casein kinase II affects DNA-protein interaction Journal of Molecular Biology. 243: 10-24. PMID 7932731 DOI: 10.1006/jmbi.1994.1626  0.327
1993 Gilson E, Roberge M, Giraldo R, Rhodes D, Gasser SM. Distortion of the DNA double helix by RAP1 at silencers and multiple telomeric binding sites. Journal of Molecular Biology. 231: 293-310. PMID 8510148 DOI: 10.1006/Jmbi.1993.1283  0.436
1992 Roberge M, Gasser SM. DNA loops: structural and functional properties of scaffold-attached regions. Molecular Microbiology. 6: 419-23. PMID 1560771 DOI: 10.1111/j.1365-2958.1992.tb01485.x  0.478
1991 Gasser SM. Replication origins, factors and attachment sites. Current Opinion in Cell Biology. 3: 407-13. PMID 1892651  0.379
1991 Raska I, Michel LS, Jarnik M, Dundr M, Fakan S, Gasser S, Gassmann M, Hubscher U, Izaurralde E, Martinez E, Richter A, Dubochet J. Ultrastructural cryoimmunocytochemistry is a convenient tool for the study of DNA replication in cultured cells Journal of Electron Microscopy Technique. 18: 91-105. PMID 1886006 DOI: 10.1002/Jemt.1060180202  0.469
1990 Amati B, Pick L, Laroche T, Gasser SM. Nuclear scaffold attachment stimulates, but is not essential for ARS activity in Saccharomyces cerevisiae: analysis of the Drosophila ftz SAR. The Embo Journal. 9: 4007-16. PMID 2123454 DOI: 10.1002/J.1460-2075.1990.Tb07622.X  0.399
1990 Amati B, Gasser SM. Drosophila scaffold-attached regions bind nuclear scaffolds and can function as ARS elements in both budding and fission yeasts. Molecular and Cellular Biology. 10: 5442-54. PMID 2118998 DOI: 10.1128/mcb.10.10.5442-5454.1990  0.345
1989 Hofmann JF, Laroche T, Brand AH, Gasser SM. RAP-1 factor is necessary for DNA loop formation in vitro at the silent mating type locus HML. Cell. 57: 725-37. PMID 2655930 DOI: 10.1016/0092-8674(89)90788-5  0.351
1988 Mirkovitch J, Gasser SM, Laemmli UK. Scaffold attachment of DNA loops in metaphase chromosomes. Journal of Molecular Biology. 200: 101-9. PMID 3132557 DOI: 10.1016/0022-2836(88)90336-1  0.687
1988 Amati BB, Gasser SM. Chromosomal ARS and CEN elements bind specifically to the yeast nuclear scaffold. Cell. 54: 967-78. PMID 2843296 DOI: 10.1016/0092-8674(88)90111-0  0.332
1987 Gasser SM, Laemmli UK. Improved methods for the isolation of individual and clustered mitotic chromosomes. Experimental Cell Research. 173: 85-98. PMID 3678386 DOI: 10.1016/0014-4827(87)90334-X  0.614
1987 Mirkovitch J, Gasser SM, Laemmli UK. Relation of chromosome structure and gene expression. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 317: 563-74. PMID 2894689 DOI: 10.1098/Rstb.1987.0081  0.634
1987 Gasser S, Laemmli U. A glimpse at chromosomal order Trends in Genetics. 3: 16-22. DOI: 10.1016/0168-9525(87)90156-9  0.666
1986 Gasser SM, Laemmli UK. The organisation of chromatin loops: characterization of a scaffold attachment site. The Embo Journal. 5: 511-8. PMID 16453673 DOI: 10.1002/J.1460-2075.1986.Tb04240.X  0.648
1986 Gasser SM, Laroche T, Falquet J, Boy de la Tour E, Laemmli UK. Metaphase chromosome structure. Involvement of topoisomerase II. Journal of Molecular Biology. 188: 613-29. PMID 3016287 DOI: 10.1016/S0022-2836(86)80010-9  0.663
1986 Gasser SM, Laemmli UK. Cohabitation of scaffold binding regions with upstream/enhancer elements of three developmentally regulated genes of D. melanogaster. Cell. 46: 521-30. PMID 3015418 DOI: 10.1016/0092-8674(86)90877-9  0.624
1983 Riezman H, Hay R, Gasser S, Daum G, Schneider G, Witte C, Schatz G. The outer membrane of yeast mitochondria: isolation of outside-out sealed vesicles. The Embo Journal. 2: 1105-11. PMID 16453466 DOI: 10.1002/J.1460-2075.1983.Tb01553.X  0.579
1983 Gasser SM, Schatz G. Import of proteins into mitochondria. In vitro studies on the biogenesis of the outer membrane. The Journal of Biological Chemistry. 258: 3427-30. PMID 6339485  0.431
1982 Gasser SM, Ohashi A, Daum G, Böhni PC, Gibson J, Reid GA, Yonetani T, Schatz G. Imported mitochondrial proteins cytochrome b2 and cytochrome c1 are processed in two steps Proceedings of the National Academy of Sciences of the United States of America. 79: 267-271. PMID 7043457 DOI: 10.1073/Pnas.79.2.267  0.401
1982 Daum G, Gasser SM, Schatz G. Import of proteins into mitochondria. Energy-dependent, two-step processing of the intermembrane space enzyme cytochrome b2 by isolated yeast mitochondria. The Journal of Biological Chemistry. 257: 13075-80. PMID 6752147  0.394
1982 Gasser SM, Daum G, Schatz G. Import of proteins into mitochondria. Energy-dependent uptake of precursors by isolated mitochondria. The Journal of Biological Chemistry. 257: 13034-41. PMID 6215405  0.385
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