| Year |
Citation |
Score |
| 2020 |
Mori T, Koyama N, Yokoo T, Segawa T, Maeda M, Sawmiller D, Tan J, Town T. Gallic Acid is a Dual α/β-Secretase Modulator that Reverses Cognitive Impairment and Remediates Pathology in Alzheimer Mice. The Journal of Biological Chemistry. PMID 32913125 DOI: 10.1074/Jbc.Ra119.012330 |
0.364 |
|
| 2020 |
Haghani A, Cacciottolo M, Doty KR, D'Agostino C, Thorwald M, Safi N, Levine ME, Sioutas C, Town TC, Forman HJ, Zhang H, Morgan TE, Finch CE. Mouse brain transcriptome responses to inhaled nanoparticulate matter differed by sex and in interactions. Elife. 9. PMID 32579111 DOI: 10.7554/Elife.54822 |
0.349 |
|
| 2019 |
Der B, Town T. P2-114: A HIGH-POWER VIEW OF PERIPHERAL MACROPHAGES IN RAT ALZHEIMER DISEASE MODEL IN VIVO Alzheimer's & Dementia. 15: P616-P616. DOI: 10.1016/J.Jalz.2019.06.2521 |
0.308 |
|
| 2018 |
Mori T, Koyama N, Tan J, Segawa T, Maeda M, Town T. Combined treatment with the phenolics (-)-epigallocatechin-3-gallate and ferulic acid improves cognition and reduces Alzheimer-like pathology in mice. The Journal of Biological Chemistry. PMID 30563837 DOI: 10.1074/Jbc.Ra118.004280 |
0.363 |
|
| 2018 |
Meyer PF, Savard M, Poirier J, Labonté A, Rosa-Neto P, Weitz TM, Town T, Breitner J. Bi-Directional Association of Cerebrospinal Fluid Immune Markers with Stage of Alzheimer's Disease Pathogenesis. Journal of Alzheimer's Disease : Jad. PMID 29660934 DOI: 10.3233/Jad-170887 |
0.378 |
|
| 2017 |
Guillot-Sestier MV, Town T. Let's make microglia great again in neurodegenerative disorders. Journal of Neural Transmission (Vienna, Austria : 1996). 125: 751-770. PMID 29027011 DOI: 10.1007/S00702-017-1792-X |
0.34 |
|
| 2017 |
Mori T, Koyama N, Tan J, Segawa T, Maeda M, Town T. Combination Therapy with Octyl Gallate and Ferulic Acid Improves Cognition and Neurodegeneration in a Transgenic Mouse Model of Alzheimer Disease. The Journal of Biological Chemistry. PMID 28512130 DOI: 10.1074/Jbc.M116.762658 |
0.347 |
|
| 2017 |
Meyer P, Poirier J, Rosa-Neto P, Weitz TM, Town T, Labonte A, Breitner JCS. Increased Pro-Inflammatory Signaling And Evidence Of Alzheimer’S Disease Pathology In Healthy Older Adults At Risk For Ad Alzheimers & Dementia. 13: 608. DOI: 10.1016/J.Jalz.2017.06.659 |
0.317 |
|
| 2016 |
Guillot-Sestier MV, Weitz TM, Town T. Quantitative 3D In Silico Modeling (q3DISM) of Cerebral Amyloid-beta Phagocytosis in Rodent Models of Alzheimer's Disease. Journal of Visualized Experiments : Jove. PMID 28060279 DOI: 10.3791/54868 |
0.391 |
|
| 2016 |
Breunig JJ, Levy R, Antonuk CD, Molina J, Dutra-Clarke M, Park H, Akhtar AA, Kim GB, Town T, Hu X, Bannykh SI, Verhaak RG, Danielpour M. Ets Factors Regulate Neural Stem Cell Depletion and Gliogenesis in Ras Pathway Glioma. Cell Reports. 17: 3407. PMID 28009307 DOI: 10.1016/j.celrep.2016.12.026 |
0.539 |
|
| 2016 |
Paul AM, Acharya D, Le L, Wang P, Stokic DS, Leis AA, Alexopoulou L, Town T, Flavell RA, Fikrig E, Bai F. TLR8 Couples SOCS-1 and Restrains TLR7-Mediated Antiviral Immunity, Exacerbating West Nile Virus Infection in Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 27798161 DOI: 10.4049/Jimmunol.1600902 |
0.44 |
|
| 2016 |
Acharya D, Wang P, Paul AM, Dai J, Gate D, Lowery JE, Stokic DS, Leis AA, Flavell RA, Town T, Fikrig E, Bai F. Interleukin-17A Promotes CD8+ T Cell Cytotoxicity to Facilitate West Nile Virus Clearance. Journal of Virology. PMID 27795421 DOI: 10.1128/Jvi.01529-16 |
0.708 |
|
| 2016 |
Weitz TM, Town T. Amyloid Cascade into Clarity. Immunity. 45: 717-718. PMID 27760336 DOI: 10.1016/J.Immuni.2016.10.006 |
0.324 |
|
| 2016 |
Heneka M, Andreasson KI, Bachstetter AD, Colonna M, Ginhoux F, Holmes C, Lamb B, Landreth G, Lee DC, Low D, Lynch MA, Monsonego A, O'Banion MK, Pekny M, Puschmann T, ... ... Town T, et al. Targeting innate immunity for neurodegenerative disorders of the central nervous system. Journal of Neurochemistry. PMID 27248001 DOI: 10.1111/Jnc.13667 |
0.354 |
|
| 2016 |
Mott KR, Gate D, Matundan HH, Ghiasi YN, Town T, Ghiasi H. CD8+ T cells play a bystander role in HSV-1 latently infected mice. Journal of Virology. PMID 26962220 DOI: 10.1128/Jvi.00255-16 |
0.682 |
|
| 2016 |
Daianu M, Jacobs RE, Town TC, Thompson PM. Axonal diameter and density estimated with 7-Tesla hybrid diffusion imaging in transgenic Alzheimer rats Proceedings of Spie. 9784. DOI: 10.1117/12.2216912 |
0.3 |
|
| 2016 |
Doty KR, Guillot-Sestier M, Town T. P4-304: STAT3 Signaling Referees Microglial Amyloid Clearance in Alzheimer’S Disease Alzheimer's & Dementia. 12: P1150-P1150. DOI: 10.1016/J.Jalz.2016.07.047 |
0.349 |
|
| 2016 |
Breitner JCS, Poirier J, Town T, Rosa-Neto P, Tremblay-Mercier J, Weitz TM. Csf Markers Of Inflammation And Alzheimer'S Disease Pathogenesis In The Cognitively Intact Prevent-Ad Cohort Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.470 |
0.355 |
|
| 2015 |
Tseng CW, Biancotti JC, Berg BL, Gate D, Kolar SL, Müller S, Rodriguez MD, Rezai-Zadeh K, Fan X, Beenhouwer DO, Town T, Liu GY. Increased Susceptibility of Humanized NSG Mice to Panton-Valentine Leukocidin and Staphylococcus aureus Skin Infection. Plos Pathogens. 11: e1005292. PMID 26618545 DOI: 10.1371/Journal.Ppat.1005292 |
0.667 |
|
| 2015 |
Guillot-Sestier MV, Doty KR, Town T. Innate Immunity Fights Alzheimer's Disease. Trends in Neurosciences. 38: 674-81. PMID 26549882 DOI: 10.1016/J.Tins.2015.08.008 |
0.419 |
|
| 2015 |
Gate D, Danielpour M, Bannykh S, Town T. Characterization of cancer stem cells and primary cilia in medulloblastoma. Cns & Neurological Disorders Drug Targets. 14: 600-11. PMID 25921740 DOI: 10.2174/1871527314666150429113851 |
0.667 |
|
| 2015 |
Heneka MT, Carson MJ, El Khoury J, Landreth GE, Brosseron F, Feinstein DL, Jacobs AH, Wyss-Coray T, Vitorica J, Ransohoff RM, Herrup K, Frautschy SA, Finsen B, Brown GC, Verkhratsky A, ... ... Town T, et al. Neuroinflammation in Alzheimer's disease. The Lancet. Neurology. 14: 388-405. PMID 25792098 DOI: 10.1016/S1474-4422(15)70016-5 |
0.578 |
|
| 2015 |
Stratigi K, Kapsetaki M, Aivaliotis M, Town T, Flavell RA, Spilianakis CG. Spatial proximity of homologous alleles and long noncoding RNAs regulate a switch in allelic gene expression. Proceedings of the National Academy of Sciences of the United States of America. 112: E1577-86. PMID 25770217 DOI: 10.1073/Pnas.1502182112 |
0.392 |
|
| 2015 |
Guillot-Sestier MV, Doty KR, Gate D, Rodriguez J, Leung BP, Rezai-Zadeh K, Town T. Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology. Neuron. 85: 534-48. PMID 25619654 DOI: 10.1016/J.Neuron.2014.12.068 |
0.761 |
|
| 2015 |
Doty KR, Guillot-Sestier MV, Town T. The role of the immune system in neurodegenerative disorders: Adaptive or maladaptive? Brain Research. 1617: 155-73. PMID 25218556 DOI: 10.1016/J.Brainres.2014.09.008 |
0.311 |
|
| 2015 |
Gate D, Doty K, Leung B, Rodriguez J, Masliah E, Town T. O2-14-02: Irak-m removal endorses microglia-mediated amyloid phagocytosis and improves cognitive impairment in psapp mice Alzheimer's & Dementia. 11: P208-P208. DOI: 10.1016/J.Jalz.2015.07.209 |
0.749 |
|
| 2015 |
Guillot-Sestier M, Doty K, Gate D, Rodriguez J, Leung B, Rezai-Zadeh K, Town T. O2-05-02: Il10 deficiency licenses innate immunity to fight against cerebral amyloidosis Alzheimer's & Dementia. 11: P183-P184. DOI: 10.1016/J.Jalz.2015.07.155 |
0.734 |
|
| 2015 |
Mori T, Town T. A Naturally Occurring β-Secretase Modulator, Tannic Acid, Improves Behavioral Impairment and Mitigates Alzheimer-Like Pathology Diet and Nutrition in Dementia and Cognitive Decline. 1069-1079. DOI: 10.1016/B978-0-12-407824-6.00100-2 |
0.385 |
|
| 2014 |
Weitz TM, Gate D, Rezai-Zadeh K, Town T. MyD88 is dispensable for cerebral amyloidosis and neuroinflammation in APP/PS1 transgenic mice. The American Journal of Pathology. 184: 2855-61. PMID 25174876 DOI: 10.1016/J.Ajpath.2014.07.004 |
0.734 |
|
| 2014 |
Mori T, Koyama N, Segawa T, Maeda M, Maruyama N, Kinoshita N, Hou H, Tan J, Town T. Methylene blue modulates β-secretase, reverses cerebral amyloidosis, and improves cognition in transgenic mice. The Journal of Biological Chemistry. 289: 30303-17. PMID 25157105 DOI: 10.1074/Jbc.M114.568212 |
0.403 |
|
| 2014 |
Gate D, Danielpour M, Rodriguez J, Kim GB, Levy R, Bannykh S, Breunig JJ, Kaech SM, Flavell RA, Town T. T-cell TGF-β signaling abrogation restricts medulloblastoma progression. Proceedings of the National Academy of Sciences of the United States of America. 111: E3458-66. PMID 25082897 DOI: 10.1073/Pnas.1412489111 |
0.775 |
|
| 2014 |
Mott KR, Allen SJ, Zandian M, Konda B, Sharifi BG, Jones C, Wechsler SL, Town T, Ghiasi H. CD8α dendritic cells drive establishment of HSV-1 latency. Plos One. 9: e93444. PMID 24695322 DOI: 10.1371/Journal.Pone.0093444 |
0.319 |
|
| 2014 |
Town T, Gate D, Doty KR, Guillot-Sestier M, Weitz TM. S4-02-02: HARNESSING INNATE IMMUNITY TO TREAT ALZHEIMER'S DISEASE Alzheimer's & Dementia. 10: P240-P240. DOI: 10.1016/J.Jalz.2014.04.359 |
0.673 |
|
| 2014 |
Gate D, Rodriguez J, Leung B, Masliah E, Town T. O3-12-02: IRAK-M DELETION PROMOTES MICROGLIA-MEDIATED Aβ PHAGOCYTOSIS AND IMPROVES COGNITION IN PSAPP MICE Alzheimer's & Dementia. 10: P233-P233. DOI: 10.1016/J.Jalz.2014.04.336 |
0.751 |
|
| 2013 |
Breunig JJ, Guillot-Sestier MV, Town T. Brain injury, neuroinflammation and Alzheimer's disease. Frontiers in Aging Neuroscience. 5: 26. PMID 23874297 DOI: 10.3389/Fnagi.2013.00026 |
0.642 |
|
| 2013 |
Cohen RM, Rezai-Zadeh K, Weitz TM, Rentsendorj A, Gate D, Spivak I, Bholat Y, Vasilevko V, Glabe CG, Breunig JJ, Rakic P, Davtyan H, Agadjanyan MG, Kepe V, Barrio JR, ... ... Town T, et al. A transgenic Alzheimer rat with plaques, tau pathology, behavioral impairment, oligomeric aβ, and frank neuronal loss. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 6245-56. PMID 23575824 DOI: 10.1523/Jneurosci.3672-12.2013 |
0.8 |
|
| 2013 |
Guillot-Sestier MV, Town T. Innate immunity in Alzheimer's disease: a complex affair. Cns & Neurological Disorders Drug Targets. 12: 593-607. PMID 23574177 DOI: 10.2174/1871527311312050008 |
0.418 |
|
| 2013 |
Biancotti JC, Town T. Increasing hematopoietic stem cell yield to develop mice with human immune systems. Biomed Research International. 2013: 740892. PMID 23509770 DOI: 10.1155/2013/740892 |
0.301 |
|
| 2013 |
Mori T, Koyama N, Guillot-Sestier MV, Tan J, Town T. Ferulic acid is a nutraceutical β-secretase modulator that improves behavioral impairment and alzheimer-like pathology in transgenic mice. Plos One. 8: e55774. PMID 23409038 DOI: 10.1371/Journal.Pone.0055774 |
0.416 |
|
| 2013 |
Gate D, Kim G, Breunig J, Masliah E, Town T. P1-026: IRAK-M deletion promotes microglia-mediated beta-amyloid phagocytosis in PSAPP mice Alzheimer's & Dementia. 9: P161-P162. DOI: 10.1016/J.Jalz.2013.05.246 |
0.77 |
|
| 2012 |
Wang P, Bai F, Zenewicz LA, Dai J, Gate D, Cheng G, Yang L, Qian F, Yuan X, Montgomery RR, Flavell RA, Town T, Fikrig E. IL-22 signaling contributes to West Nile encephalitis pathogenesis. Plos One. 7: e44153. PMID 22952908 DOI: 10.1371/Journal.Pone.0044153 |
0.705 |
|
| 2012 |
Weitz TM, Town T. Microglia in Alzheimer's Disease: It's All About Context. International Journal of Alzheimer's Disease. 2012: 314185. PMID 22779026 DOI: 10.1155/2012/314185 |
0.413 |
|
| 2012 |
Breunig JJ, Gate D, Levy R, Rodriguez J, Kim GB, Danielpour M, Svendsen CN, Town T. Rapid genetic targeting of pial surface neural progenitors and immature neurons by neonatal electroporation. Neural Development. 7: 26. PMID 22776033 DOI: 10.1186/1749-8104-7-26 |
0.738 |
|
| 2012 |
Gate D, Danielpour M, Levy R, Breunig JJ, Town T. Basic biology and mechanisms of neural ciliogenesis and the B9 family. Molecular Neurobiology. 45: 564-70. PMID 22644387 DOI: 10.1007/S12035-012-8276-7 |
0.743 |
|
| 2012 |
Mori T, Rezai-Zadeh K, Koyama N, Arendash GW, Yamaguchi H, Kakuda N, Horikoshi-Sakuraba Y, Tan J, Town T. Tannic acid is a natural β-secretase inhibitor that prevents cognitive impairment and mitigates Alzheimer-like pathology in transgenic mice. The Journal of Biological Chemistry. 287: 6912-27. PMID 22219198 DOI: 10.1074/Jbc.M111.294025 |
0.425 |
|
| 2012 |
Carvalho D, Bjerke L, Bax D, Chen L, Kozarewa I, Baker S, Grundy R, Ashworth A, Lord C, Hargrave D, Reis RM, Jones C, Bender S, Feng W, Jones DT, ... ... Town T, et al. LAB-PEDIATRICS LABORATORY RESEARCH Neuro-Oncology. 14: vi116-vi119. DOI: 10.1093/Neuonc/Nos235 |
0.713 |
|
| 2012 |
Weitz T, Das M, Rezai-Zadeh K, Gate D, Town T. P2-119: MyD88 is dispensable for cerebral amyloid pathology and neuroinflammation in PSAPP transgenic mice Alzheimer's & Dementia. 8: P302-P303. DOI: 10.1016/J.Jalz.2012.05.824 |
0.698 |
|
| 2012 |
Town T, Rezai-Zadeh K, Breunig J, Tan J, Mori T. O1-11-04: Naturally occurring beta-secretase inhibitors mitigate behavioral impairment, cerebral amyloidosis and neuroinflammation in transgenic mice Alzheimer's & Dementia. 8: P105-P105. DOI: 10.1016/J.Jalz.2012.05.266 |
0.635 |
|
| 2012 |
Breunig J, Rezai-Zadeh K, Rentsendorj A, Gate D, Cohen R, Town T. P2-416: Adult neurogenesis is diminished in a novel rat model of Alzheimer's disease Alzheimer's & Dementia. 8: P409-P410. DOI: 10.1016/J.Jalz.2012.05.2041 |
0.753 |
|
| 2012 |
Gate D, Rezai-Zadeh K, Masliah E, Town T. O4-07-01: IRAK-M deletion promotes microglia-mediated cerebral amyloid clearance in PSAPP mice Alzheimer's & Dementia. 8: P627-P627. DOI: 10.1016/J.Jalz.2012.05.1671 |
0.693 |
|
| 2011 |
Allen SJ, Mott KR, Wechsler SL, Flavell RA, Town T, Ghiasi H. Adaptive and innate transforming growth factor beta signaling impact herpes simplex virus 1 latency and reactivation. Journal of Virology. 85: 11448-56. PMID 21880769 DOI: 10.1128/Jvi.00678-11 |
0.458 |
|
| 2011 |
Esplugues E, Huber S, Gagliani N, Hauser AE, Town T, Wan YY, O'Connor W, Rongvaux A, Van Rooijen N, Haberman AM, Iwakura Y, Kuchroo VK, Kolls JK, Bluestone JA, Herold KC, et al. Control of TH17 cells occurs in the small intestine. Nature. 475: 514-8. PMID 21765430 DOI: 10.1038/Nature10228 |
0.411 |
|
| 2011 |
Rezai-Zadeh K, Gate D, Gowing G, Town T. How to get from here to there: macrophage recruitment in Alzheimer's disease. Current Alzheimer Research. 8: 156-63. PMID 21345166 DOI: 10.2174/156720511795256017 |
0.732 |
|
| 2011 |
Allen SJ, Hamrah P, Gate D, Mott KR, Mantopoulos D, Zheng L, Town T, Jones C, von Andrian UH, Freeman GJ, Sharpe AH, BenMohamed L, Ahmed R, Wechsler SL, Ghiasi H. The role of LAT in increased CD8+ T cell exhaustion in trigeminal ganglia of mice latently infected with herpes simplex virus 1. Journal of Virology. 85: 4184-97. PMID 21307196 DOI: 10.1128/Jvi.02290-10 |
0.668 |
|
| 2011 |
Zhu Y, Hou H, Rezai-Zadeh K, Giunta B, Ruscin A, Gemma C, Jin J, Dragicevic N, Bradshaw P, Rasool S, Glabe CG, Ehrhart J, Bickford P, Mori T, Obregon D, ... Town T, et al. CD45 deficiency drives amyloid-β peptide oligomers and neuronal loss in Alzheimer's disease mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 1355-65. PMID 21273420 DOI: 10.1523/Jneurosci.3268-10.2011 |
0.401 |
|
| 2011 |
Mott KR, Gate D, Zandian M, Allen SJ, Rajasagi NK, van Rooijen N, Chen S, Arditi M, Rouse BT, Flavell RA, Town T, Ghiasi H. Macrophage IL-12p70 signaling prevents HSV-1-induced CNS autoimmunity triggered by autoaggressive CD4+ Tregs. Investigative Ophthalmology & Visual Science. 52: 2321-33. PMID 21220560 DOI: 10.1167/Iovs.10-6536 |
0.721 |
|
| 2011 |
Zhu Y, Obregon D, Hou H, Giunta B, Ehrhart J, Fernandez F, Mori T, Nikolic W, Zhao Y, Morgan D, Town T, Tan J. Mutant presenilin-1 deregulated peripheral immunity exacerbates Alzheimer-like pathology. Journal of Cellular and Molecular Medicine. 15: 327-38. PMID 19900216 DOI: 10.1111/J.1582-4934.2009.00962.X |
0.426 |
|
| 2011 |
Gate D, Masliah E, Rezai-Zadeh K, Town T, Rentsendorj A. O1-03-05: IRAK-M deletion activates microglia and restricts cerebral amyloid in PSAPP mice Alzheimer's & Dementia. 7: S99-S99. DOI: 10.1016/J.Jalz.2011.05.243 |
0.69 |
|
| 2011 |
Rezai-Zadeh K, Breunig J, Rentsendorj A, Gate D, Cohen R, Town T. O3-04-03: Disrupted adult neurogenesis in a novel rat model of Alzheimer's disease Alzheimer's & Dementia. 7: S505-S505. DOI: 10.1016/J.Jalz.2011.05.1410 |
0.753 |
|
| 2010 |
Mori T, Asano T, Town T. Targeting S100B in Cerebral Ischemia and in Alzheimer's Disease. Cardiovascular Psychiatry and Neurology. 2010. PMID 20862385 DOI: 10.1155/2010/687067 |
0.363 |
|
| 2010 |
Gate D, Rezai-Zadeh K, Jodry D, Rentsendorj A, Town T. Macrophages in Alzheimer's disease: the blood-borne identity. Journal of Neural Transmission (Vienna, Austria : 1996). 117: 961-70. PMID 20517700 DOI: 10.1007/S00702-010-0422-7 |
0.723 |
|
| 2010 |
Town T. Alzheimer's Disease Beyond Abeta. Expert Review of Neurotherapeutics. 10: 671-5. PMID 20429127 DOI: 10.1586/Ern.10.50 |
0.379 |
|
| 2010 |
Town T. Inflammation, immunity, and Alzheimer's disease. Cns & Neurological Disorders Drug Targets. 9: 129-31. PMID 20205648 DOI: 10.2174/187152710791012008 |
0.362 |
|
| 2010 |
Mori T, Koyama N, Arendash GW, Horikoshi-Sakuraba Y, Tan J, Town T. Overexpression of human S100B exacerbates cerebral amyloidosis and gliosis in the Tg2576 mouse model of Alzheimer's disease. Glia. 58: 300-14. PMID 19705461 DOI: 10.1002/Glia.20924 |
0.448 |
|
| 2010 |
Town T, Rezai-Zadeh K, Ye D, Rentsendorj A, Johnson S, Spivak I, Bholat Y, Bannykh S, Breunig JJ, Rakic P, Pechnick RN, Cohen RM. S4-03-05: Elucidation of the Amyloid Cascade Hypothesis in the TgF344-AD Rat Alzheimer's & Dementia. 6: e14-e14. DOI: 10.1016/J.Jalz.2010.08.044 |
0.707 |
|
| 2010 |
Rezai-Zadeh K, Gate D, Rentsendorj A, Jodry D, Mori T, Szekely CA, Tan J, Town T. P1-324: TGF-β and IL-10: An Alzheimer immunoregulatory duet? Alzheimer's & Dementia. 6: S267-S267. DOI: 10.1016/J.Jalz.2010.05.877 |
0.666 |
|
| 2010 |
Tan J, Zhu Y, Hou H, Jin J, Mori T, Gemma C, Obregon D, Dragicevic N, Bradshaw P, Bickford P, Town T, Giunta B. CD45 deficency promotes neurodegeneration in PSAPP mice Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.423 |
0.314 |
|
| 2010 |
Gate D, Rezai-Zadeh K, Goodridge H, Rodriguez J, Jodry D, Underhill D, Town T. P3-416: Differential TGF-β-Smad 2/3 and BMP-Smad 1/5/8 pathway activation promotes macrophage Aβ phagocytosis Alzheimer's & Dementia. 6: S574-S575. DOI: 10.1016/J.Jalz.2010.05.1959 |
0.667 |
|
| 2009 |
Rezai-Zadeh K, Gate D, Szekely CA, Town T. Can peripheral leukocytes be used as Alzheimer's disease biomarkers? Expert Review of Neurotherapeutics. 9: 1623-33. PMID 19903022 DOI: 10.1586/Ern.09.118 |
0.682 |
|
| 2009 |
Bai F, Town T, Qian F, Wang P, Kamanaka M, Connolly TM, Gate D, Montgomery RR, Flavell RA, Fikrig E. IL-10 signaling blockade controls murine West Nile virus infection. Plos Pathogens. 5: e1000610. PMID 19816558 DOI: 10.1371/Journal.Ppat.1000610 |
0.692 |
|
| 2009 |
Giunta B, Figueroa KP, Town T, Tan J. SOLUBLE CD40 LIGAND IN DEMENTIA. Drugs of the Future. 34: 333-340. PMID 19777117 DOI: 10.1358/Dof.2009.034.04.1358595 |
0.342 |
|
| 2009 |
Rezai-Zadeh K, Gate D, Town T. CNS infiltration of peripheral immune cells: D-Day for neurodegenerative disease? Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 4: 462-75. PMID 19669892 DOI: 10.1007/S11481-009-9166-2 |
0.686 |
|
| 2009 |
O'Connor W, Kamanaka M, Booth CJ, Town T, Nakae S, Iwakura Y, Kolls JK, Flavell RA. A protective function for interleukin 17A in T cell-mediated intestinal inflammation. Nature Immunology. 10: 603-9. PMID 19448631 DOI: 10.1038/Ni.1736 |
0.431 |
|
| 2009 |
Town T. Alternative Abeta immunotherapy approaches for Alzheimer's disease. Cns & Neurological Disorders Drug Targets. 8: 114-27. PMID 19355932 DOI: 10.2174/187152709787847306 |
0.381 |
|
| 2009 |
Town T, Bai F, Wang T, Kaplan AT, Qian F, Montgomery RR, Anderson JF, Flavell RA, Fikrig E. Toll-like receptor 7 mitigates lethal West Nile encephalitis via interleukin 23-dependent immune cell infiltration and homing. Immunity. 30: 242-53. PMID 19200759 DOI: 10.1016/J.Immuni.2008.11.012 |
0.466 |
|
| 2009 |
Rezai-Zadeh K, Douglas Shytle R, Bai Y, Tian J, Hou H, Mori T, Zeng J, Obregon D, Town T, Tan J. Flavonoid-mediated presenilin-1 phosphorylation reduces Alzheimer's disease beta-amyloid production. Journal of Cellular and Molecular Medicine. 13: 574-88. PMID 18410522 DOI: 10.1111/J.1582-4934.2008.00344.X |
0.416 |
|
| 2009 |
Tan J, Zhu Y, Oregon D, Hou H, Luo D, Mori T, Giunta B, Zhao Y, Town T. O2-05-04: Immune system reconstitution reduces Aβ/β-amyloid pathology in PSAPP mice Alzheimer's & Dementia. 5: P113-P113. DOI: 10.1016/J.Jalz.2009.05.355 |
0.371 |
|
| 2008 |
Giunta B, Fernandez F, Nikolic WV, Obregon D, Rrapo E, Town T, Tan J. Inflammaging as a prodrome to Alzheimer's disease. Journal of Neuroinflammation. 5: 51. PMID 19014446 DOI: 10.1186/1742-2094-5-51 |
0.378 |
|
| 2008 |
Breunig JJ, Sarkisian MR, Arellano JI, Morozov YM, Ayoub AE, Sojitra S, Wang B, Flavell RA, Rakic P, Town T. Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling. Proceedings of the National Academy of Sciences of the United States of America. 105: 13127-32. PMID 18728187 DOI: 10.1073/Pnas.0804558105 |
0.762 |
|
| 2008 |
Laouar Y, Town T, Jeng D, Tran E, Wan Y, Kuchroo VK, Flavell RA. TGF-beta signaling in dendritic cells is a prerequisite for the control of autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. 105: 10865-70. PMID 18669656 DOI: 10.1073/Pnas.0805058105 |
0.476 |
|
| 2008 |
Wang S, Welte T, McGargill M, Town T, Thompson J, Anderson JF, Flavell RA, Fikrig E, Hedrick SM, Wang T. Drak2 contributes to West Nile virus entry into the brain and lethal encephalitis. Journal of Immunology (Baltimore, Md. : 1950). 181: 2084-91. PMID 18641347 DOI: 10.4049/Jimmunol.181.3.2084 |
0.464 |
|
| 2008 |
Town T, Laouar Y, Pittenger C, Mori T, Szekely CA, Tan J, Duman RS, Flavell RA. Blocking TGF-beta-Smad2/3 innate immune signaling mitigates Alzheimer-like pathology. Nature Medicine. 14: 681-7. PMID 18516051 DOI: 10.1038/Nm1781 |
0.507 |
|
| 2008 |
Mori T, Tan J, Arendash GW, Koyama N, Nojima Y, Town T. Overexpression of human S100B exacerbates brain damage and periinfarct gliosis after permanent focal ischemia. Stroke; a Journal of Cerebral Circulation. 39: 2114-21. PMID 18451356 DOI: 10.1161/Strokeaha.107.503821 |
0.342 |
|
| 2008 |
Mohanty S, Town T, Yagi T, Scheidig C, Kwan KY, Allore HG, Flavell RA, Shaw AC. Defective p53 engagement after the induction of DNA damage in cells deficient in topoisomerase 3beta. Proceedings of the National Academy of Sciences of the United States of America. 105: 5063-8. PMID 18367668 DOI: 10.1073/Pnas.0801235105 |
0.388 |
|
| 2008 |
Nikolic WV, Hou H, Town T, Zhu Y, Giunta B, Sanberg CD, Zeng J, Luo D, Ehrhart J, Mori T, Sanberg PR, Tan J. Peripherally administered human umbilical cord blood cells reduce parenchymal and vascular beta-amyloid deposits in Alzheimer mice. Stem Cells and Development. 17: 423-39. PMID 18366296 DOI: 10.1089/Scd.2008.0018 |
0.454 |
|
| 2008 |
Town T, Breunig JJ, Sarkisian MR, Spilianakis C, Ayoub AE, Liu X, Ferrandino AF, Gallagher AR, Li MO, Rakic P, Flavell RA. The stumpy gene is required for mammalian ciliogenesis. Proceedings of the National Academy of Sciences of the United States of America. 105: 2853-8. PMID 18287022 DOI: 10.1073/Pnas.0712385105 |
0.757 |
|
| 2008 |
Obregon D, Hou H, Bai Y, Nikolic WV, Mori T, Luo D, Zeng J, Ehrhart J, Fernandez F, Morgan D, Giunta B, Town T, Tan J. CD40L disruption enhances Abeta vaccine-mediated reduction of cerebral amyloidosis while minimizing cerebral amyloid angiopathy and inflammation. Neurobiology of Disease. 29: 336-53. PMID 18055209 DOI: 10.1016/J.Nbd.2007.09.009 |
0.413 |
|
| 2008 |
Town T, Laouar Y, Pittenger C, Mori T, Szekely CA, Tan J, Duman RS, Flavell RA. O4-02-06: Blocking Tgf-β-smad 2/3 innate immune signaling mitigates Alzheimer-like pathology in transgenic mice Alzheimer's & Dementia. 4: T187-T188. DOI: 10.1016/J.Jalz.2008.05.514 |
0.481 |
|
| 2007 |
Griffith JW, O'Connor C, Bernard K, Town T, Goldstein DR, Bucala R. Toll-like receptor modulation of murine cerebral malaria is dependent on the genetic background of the host. The Journal of Infectious Diseases. 196: 1553-64. PMID 18008236 DOI: 10.1086/522865 |
0.331 |
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| 2007 |
Deane JA, Pisitkun P, Barrett RS, Feigenbaum L, Town T, Ward JM, Flavell RA, Bolland S. Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation. Immunity. 27: 801-10. PMID 17997333 DOI: 10.1016/J.Immuni.2007.09.009 |
0.425 |
|
| 2007 |
Arjona A, Foellmer HG, Town T, Leng L, McDonald C, Wang T, Wong SJ, Montgomery RR, Fikrig E, Bucala R. Abrogation of macrophage migration inhibitory factor decreases West Nile virus lethality by limiting viral neuroinvasion. The Journal of Clinical Investigation. 117: 3059-66. PMID 17909632 DOI: 10.1172/Jci32218 |
0.333 |
|
| 2007 |
Watanabe A, Hashmi A, Gomes DA, Town T, Badou A, Flavell RA, Mehal WZ. Apoptotic hepatocyte DNA inhibits hepatic stellate cell chemotaxis via toll-like receptor 9. Hepatology (Baltimore, Md.). 46: 1509-18. PMID 17705260 DOI: 10.1002/Hep.21867 |
0.419 |
|
| 2007 |
Szekely CA, Town T, Zandi PP. NSAIDs for the chemoprevention of Alzheimer's disease. Sub-Cellular Biochemistry. 42: 229-48. PMID 17612054 DOI: 10.1007/1-4020-5688-5_11 |
0.372 |
|
| 2007 |
Nikolic WV, Bai Y, Obregon D, Hou H, Mori T, Zeng J, Ehrhart J, Shytle RD, Giunta B, Morgan D, Town T, Tan J. Transcutaneous beta-amyloid immunization reduces cerebral beta-amyloid deposits without T cell infiltration and microhemorrhage. Proceedings of the National Academy of Sciences of the United States of America. 104: 2507-12. PMID 17264212 DOI: 10.1073/Pnas.0609377104 |
0.387 |
|
| 2007 |
Bai F, Town T, Pradhan D, Cox J, Ashish, Ledizet M, Anderson JF, Flavell RA, Krueger JK, Koski RA, Fikrig E. Antiviral peptides targeting the west nile virus envelope protein. Journal of Virology. 81: 2047-55. PMID 17151121 DOI: 10.1128/Jvi.01840-06 |
0.4 |
|
| 2006 |
Wang R, Town T, Gokarn V, Flavell RA, Chandawarkar RY. HSP70 enhances macrophage phagocytosis by interaction with lipid raft-associated TLR-7 and upregulating p38 MAPK and PI3K pathways. The Journal of Surgical Research. 136: 58-69. PMID 16979664 DOI: 10.1016/J.Jss.2006.06.003 |
0.426 |
|
| 2006 |
Mori T, Town T, Tan J, Yada N, Horikoshi Y, Yamamoto J, Shimoda T, Kamanaka Y, Tateishi N, Asano T. Arundic Acid ameliorates cerebral amyloidosis and gliosis in Alzheimer transgenic mice. The Journal of Pharmacology and Experimental Therapeutics. 318: 571-8. PMID 16709678 DOI: 10.1124/Jpet.106.105171 |
0.416 |
|
| 2006 |
Obregon DF, Rezai-Zadeh K, Bai Y, Sun N, Hou H, Ehrhart J, Zeng J, Mori T, Arendash GW, Shytle D, Town T, Tan J. ADAM10 activation is required for green tea (-)-epigallocatechin-3-gallate-induced alpha-secretase cleavage of amyloid precursor protein. The Journal of Biological Chemistry. 281: 16419-27. PMID 16624814 DOI: 10.1074/Jbc.M600617200 |
0.311 |
|
| 2006 |
Town T, Jeng D, Alexopoulou L, Tan J, Flavell RA. Microglia recognize double-stranded RNA via TLR3. Journal of Immunology (Baltimore, Md. : 1950). 176: 3804-12. PMID 16517751 DOI: 10.4049/Jimmunol.176.6.3804 |
0.455 |
|
| 2006 |
Vesling AW, Gate D, Doty KR, Leung BPY, Rodriguez J, Uchoa MF, van't Veer C, Town T. P2-200: IRAK-M PROMOTES MICROGLIAL Aβ TOLERANCE BY ACTIVATING ALTERNATIVE NF-KB SIGNALING Alzheimer's & Dementia. 14: P745-P745. DOI: 10.1016/J.Jalz.2018.06.887 |
0.668 |
|
| 2006 |
Uchoa MF, Doty KR, Vesling AW, Oseas R, Yan Leung BP, Quihuis AM, Guillot-Sestier M, Town T. P2-190: STAT3 INDUCIBLE DELETION IN MONONUCLEAR PHAGOCYTES IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P741-P741. DOI: 10.1016/J.Jalz.2018.06.877 |
0.35 |
|
| 2006 |
Im KW, Guillot-Sestier M, Vesling AW, Rodriguez J, Rezai-Zadeh K, Town T. O4-02-06: T CELL TGF-BETA SIGNALING CONTROL OF THE IMMUNE RESPONSE TO CEREBRAL AB Alzheimer's & Dementia. 14: P1404-P1404. DOI: 10.1016/J.Jalz.2018.06.2920 |
0.31 |
|
| 2006 |
Yan Leung BP, Doty KR, Miller CJ, Vesling AW, Uchoa MF, Im KW, Gate D, Quihuis AM, Guillot-Sestier M, Rodriguez J, Chang KT, Fahmy T, Tenner A, Colonna M, Town T. O4-02-03: PHYSICAL INTERACTION OF TREM2 AND C1Q IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P1403-P1403. DOI: 10.1016/J.Jalz.2018.06.2917 |
0.668 |
|
| 2006 |
Quihuis AM, Weitz TM, Yan Leung BP, Kim D, Rodriguez J, Fahmy T, Town T. P1-015: NANOPARTICLE TGF-β SIGNALING BLOCKADE IN TREM2+
PERIPHERAL MACROPHAGES ATTENUATES ALZHEIMER PATHOLOGY IN TGF344-AD RATS Alzheimer's & Dementia. 14: P270-P270. DOI: 10.1016/J.Jalz.2018.06.016 |
0.337 |
|
| 2005 |
Town T, Nikolic V, Tan J. The microglial "activation" continuum: from innate to adaptive responses. Journal of Neuroinflammation. 2: 24. PMID 16259628 DOI: 10.1186/1742-2094-2-24 |
0.37 |
|
| 2005 |
Town T, Tan J, Flavell RA, Mullan M. T-cells in Alzheimer's disease. Neuromolecular Medicine. 7: 255-64. PMID 16247185 DOI: 10.1385/Nmm:7:3:255 |
0.642 |
|
| 2005 |
Rezai-Zadeh K, Shytle D, Sun N, Mori T, Hou H, Jeanniton D, Ehrhart J, Townsend K, Zeng J, Morgan D, Hardy J, Town T, Tan J. Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 8807-14. PMID 16177050 DOI: 10.1523/Jneurosci.1521-05.2005 |
0.509 |
|
| 2005 |
Kimberly WT, Zheng JB, Town T, Flavell RA, Selkoe DJ. Physiological regulation of the beta-amyloid precursor protein signaling domain by c-Jun N-terminal kinase JNK3 during neuronal differentiation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5533-43. PMID 15944381 DOI: 10.1523/Jneurosci.4883-04.2005 |
0.442 |
|
| 2005 |
Spilianakis CG, Lalioti MD, Town T, Lee GR, Flavell RA. Interchromosomal associations between alternatively expressed loci. Nature. 435: 637-45. PMID 15880101 DOI: 10.1038/Nature03574 |
0.417 |
|
| 2005 |
Mori T, Town T, Tan J, Tateishi N, Asano T. Modulation of astrocytic activation by arundic acid (ONO-2506) mitigates detrimental effects of the apolipoprotein E4 isoform after permanent focal ischemia in apolipoprotein E knock-in mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 25: 748-62. PMID 15689951 DOI: 10.1038/Sj.Jcbfm.9600063 |
0.333 |
|
| 2005 |
Townsend KP, Town T, Mori T, Lue LF, Shytle D, Sanberg PR, Morgan D, Fernandez F, Flavell RA, Tan J. CD40 signaling regulates innate and adaptive activation of microglia in response to amyloid beta-peptide. European Journal of Immunology. 35: 901-10. PMID 15688347 DOI: 10.1002/Eji.200425585 |
0.535 |
|
| 2004 |
Wang T, Town T, Alexopoulou L, Anderson JF, Fikrig E, Flavell RA. Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis. Nature Medicine. 10: 1366-73. PMID 15558055 DOI: 10.1038/Nm1140 |
0.444 |
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| 2004 |
Todd Roach J, Volmar CH, Dwivedi S, Town T, Crescentini R, Crawford F, Tan J, Mullan M. Behavioral effects of CD40-CD40L pathway disruption in aged PSAPP mice. Brain Research. 1015: 161-8. PMID 15223380 DOI: 10.1016/J.Brainres.2004.05.004 |
0.743 |
|
| 2004 |
Mori T, Town T, Kobayashi M, Tan J, Fujita SC, Asano T. Augmented delayed infarct expansion and reactive astrocytosis after permanent focal ischemia in apolipoprotein E4 knock-in mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 24: 646-56. PMID 15181372 DOI: 10.1097/01.Wcb.0000120787.53851.A4 |
0.305 |
|
| 2004 |
Townsend KP, Vendrame M, Ehrhart J, Faza B, Zeng J, Town T, Tan J. CD45 isoform RB as a molecular target to oppose lipopolysaccharide-induced microglial activation in mice. Neuroscience Letters. 362: 26-30. PMID 15147773 DOI: 10.1016/J.Neulet.2004.01.082 |
0.332 |
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| 2004 |
Mott RT, Ait-Ghezala G, Town T, Mori T, Vendrame M, Zeng J, Ehrhart J, Mullan M, Tan J. Neuronal expression of CD22: novel mechanism for inhibiting microglial proinflammatory cytokine production. Glia. 46: 369-79. PMID 15095367 DOI: 10.1002/Glia.20009 |
0.522 |
|
| 2004 |
Tan J, Townsend K, Lue L, Sun N, Zeng J, Mori T, Shytle D, Morgan D, Town T. P3-410 Regulation of the innate and adaptive activation of microglia in responses to Aβ by CD40 signaling Neurobiology of Aging. 25: S471. DOI: 10.1016/S0197-4580(04)81557-4 |
0.34 |
|
| 2003 |
Mori T, Kobayashi M, Town T, Fujita SC, Asano T. Increased vulnerability to focal ischemic brain injury in human apolipoprotein E4 knock-in mice. Journal of Neuropathology and Experimental Neurology. 62: 280-91. PMID 12638732 DOI: 10.1093/Jnen/62.3.280 |
0.338 |
|
| 2002 |
Tan J, Town T, Abdullah L, Wu Y, Placzek A, Small B, Kroeger J, Crawford F, Richards D, Mullan M. CD45 isoform alteration in CD4+ T cells as a potential diagnostic marker of Alzheimer's disease. Journal of Neuroimmunology. 132: 164-72. PMID 12417447 DOI: 10.1016/S0165-5728(02)00309-0 |
0.55 |
|
| 2002 |
Town T, Vendrame M, Patel A, Poetter D, DelleDonne A, Mori T, Smeed R, Crawford F, Klein T, Tan J, Mullan M. Reduced Th1 and enhanced Th2 immunity after immunization with Alzheimer's beta-amyloid(1-42). Journal of Neuroimmunology. 132: 49-59. PMID 12417433 DOI: 10.1016/S0165-5728(02)00307-7 |
0.568 |
|
| 2002 |
Tan J, Town T, Crawford F, Mori T, DelleDonne A, Crescentini R, Obregon D, Flavell RA, Mullan MJ. Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice. Nature Neuroscience. 5: 1288-93. PMID 12402041 DOI: 10.1038/Nn968 |
0.655 |
|
| 2002 |
Tan J, Town T, Mullan M. CD40-CD40L interaction in Alzheimer's disease. Current Opinion in Pharmacology. 2: 445-51. PMID 12127879 DOI: 10.1016/S1471-4892(02)00180-7 |
0.589 |
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| 2002 |
Town T, Zolton J, Shaffner R, Schnell B, Crescentini R, Wu Y, Zeng J, DelleDonne A, Obregon D, Tan J, Mullan M. p35/Cdk5 pathway mediates soluble amyloid-beta peptide-induced tau phosphorylation in vitro. Journal of Neuroscience Research. 69: 362-72. PMID 12125077 DOI: 10.1002/Jnr.10299 |
0.562 |
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| 2002 |
Ait-Ghezala G, Abdullah L, Crescentini R, Crawford F, Town T, Singh S, Richards D, Duara R, Mullan M. Confirmation of association between D10S583 and Alzheimer's disease in a case--control sample. Neuroscience Letters. 325: 87-90. PMID 12044628 DOI: 10.1016/S0304-3940(02)00243-4 |
0.53 |
|
| 2002 |
Tan J, Town T, Mori T, Obregon D, Wu Y, DelleDonne A, Rojiani A, Crawford F, Flavell RA, Mullan M. CD40 is expressed and functional on neuronal cells. The Embo Journal. 21: 643-52. PMID 11847112 DOI: 10.1093/Emboj/21.4.643 |
0.583 |
|
| 2002 |
Schinka JA, Town T, Abdullah L, Crawford FC, Ordorica PI, Francis E, Hughes P, Graves AB, Mortimer JA, Mullan M. A functional polymorphism within the mu-opioid receptor gene and risk for abuse of alcohol and other substances. Molecular Psychiatry. 7: 224-8. PMID 11840318 DOI: 10.1038/Sj.Mp.4000951 |
0.453 |
|
| 2001 |
Town T, Tan J, Mullan M. CD40 signaling and Alzheimer's disease pathogenesis. Neurochemistry International. 39: 371-80. PMID 11578772 DOI: 10.1016/S0197-0186(01)00044-4 |
0.566 |
|
| 2001 |
Mori T, Paris D, Town T, Rojiani AM, Sparks DL, Delledonne A, Crawford F, Abdullah LI, Humphrey JA, Dickson DW, Mullan MJ. Cholesterol accumulates in senile plaques of Alzheimer disease patients and in transgenic APP(SW) mice. Journal of Neuropathology and Experimental Neurology. 60: 778-85. PMID 11487052 DOI: 10.1093/Jnen/60.8.778 |
0.567 |
|
| 2001 |
Town T, Tan J, Sansone N, Obregon D, Klein T, Mullan M. Characterization of murine immunoglobulin G antibodies against human amyloid-beta1-42. Neuroscience Letters. 307: 101-4. PMID 11427310 DOI: 10.1016/S0304-3940(01)01951-6 |
0.54 |
|
| 2000 |
Town T, Schinka J, Tan J, Mullan M. The opioid receptor system and alcoholism: a genetic perspective. European Journal of Pharmacology. 410: 243-248. PMID 11134673 DOI: 10.1016/S0014-2999(00)00818-9 |
0.379 |
|
| 2000 |
Tan J, Town T, Mori T, Wu Y, Saxe M, Crawford F, Mullan M. CD45 opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42 mitogen-activated protein kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 7587-94. PMID 11027218 DOI: 10.1523/Jneurosci.20-20-07587.2000 |
0.585 |
|
| 2000 |
Tan J, Town T, Mullan M. CD45 inhibits CD40L-induced microglial activation via negative regulation of the Src/p44/42 MAPK pathway. The Journal of Biological Chemistry. 275: 37224-31. PMID 10978311 DOI: 10.1074/Jbc.M002006200 |
0.518 |
|
| 2000 |
Paris D, Town T, Humphrey J, Yokota K, Mullan M. Cholesterol modulates vascular reactivity to endothelin-1 by stimulating a pro-inflammatory pathway. Biochemical and Biophysical Research Communications. 274: 553-8. PMID 10913376 DOI: 10.1006/Bbrc.2000.3174 |
0.473 |
|
| 2000 |
Paris D, Town T, Mori T, Parker TA, Humphrey J, Mullan M. Soluble beta-amyloid peptides mediate vasoactivity via activation of a pro-inflammatory pathway. Neurobiology of Aging. 21: 183-97. PMID 10867203 DOI: 10.1016/S0197-4580(99)00111-6 |
0.539 |
|
| 2000 |
Paris D, Town T, Parker T, Humphrey J, Mullan M. beta-Amyloid vasoactivity and proinflammation in microglia can be blocked by cGMP-elevating agents. Annals of the New York Academy of Sciences. 903: 446-50. PMID 10818536 DOI: 10.1111/J.1749-6632.2000.Tb06397.X |
0.506 |
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| 2000 |
Paris D, Town T, Parker T, Humphrey J, Mullan M. A beta vasoactivity: an inflammatory reaction. Annals of the New York Academy of Sciences. 903: 97-109. PMID 10818494 DOI: 10.1111/J.1749-6632.2000.Tb06355.X |
0.518 |
|
| 2000 |
Paris D, Town T, Mullan M. Novel strategies for opposing murine microglial activation. Neuroscience Letters. 278: 5-8. PMID 10643787 DOI: 10.1016/S0304-3940(99)00901-5 |
0.496 |
|
| 2000 |
Tan J, Town T, Paris D, Mori T, Crawford F, Mullan M. The CD40-CD40L interaction leads to microglial activation following β-amyloid stimulation Neurobiology of Aging. 21: 188. DOI: 10.1016/S0197-4580(00)82186-7 |
0.517 |
|
| 2000 |
Townsend K, Paris D, Town T, Humphrey J, Yokota K, Mullan M. Cholesterol as well as Aβ induces vasoconstruction by stimulating a similar pro-inflammatory pathway Neurobiology of Aging. 21: 180. DOI: 10.1016/S0197-4580(00)82149-1 |
0.503 |
|
| 2000 |
Town T, Tan J, Paris D, Wu Y, Mullan M. Ligation of microglial CD40 results in SRC kinase-induced P44/42 mapk-dependent TNFα-production Neurobiology of Aging. 21: 180. DOI: 10.1016/S0197-4580(00)82146-6 |
0.482 |
|
| 1999 |
Tan J, Town T, Paris D, Mori T, Suo Z, Crawford F, Mattson MP, Flavell RA, Mullan M. Microglial activation resulting from CD40-CD40L interaction after beta-amyloid stimulation. Science (New York, N.Y.). 286: 2352-5. PMID 10600748 DOI: 10.1126/Science.286.5448.2352 |
0.648 |
|
| 1999 |
Tan J, Town T, Saxe M, Paris D, Wu Y, Mullan M. Ligation of microglial CD40 results in p44/42 mitogen-activated protein kinase-dependent TNF-alpha production that is opposed by TGF-beta 1 and IL-10. Journal of Immunology (Baltimore, Md. : 1950). 163: 6614-21. PMID 10586056 |
0.463 |
|
| 1999 |
Tan J, Town T, Suo Z, Wu Y, Song S, Kundtz A, Kroeger J, Humphrey J, Crawford F, Mullan M. Induction of CD40 on human endothelial cells by Alzheimer's beta-amyloid peptides. Brain Research Bulletin. 50: 143-8. PMID 10535333 DOI: 10.1016/S0361-9230(99)00122-7 |
0.548 |
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| 1999 |
Tan J, Town T, Placzek A, Kundtz A, Yu H, Mullan M. Bcl-X(L) inhibits apoptosis and necrosis produced by Alzheimer's beta-amyloid1-40 peptide in PC12 cells. Neuroscience Letters. 272: 5-8. PMID 10507529 DOI: 10.1016/S0304-3940(99)00525-X |
0.441 |
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| 1999 |
Town T, Paris D, Parker TA, Kundtz A, Tan J, Duara R, Gold M, Crawford F, Mullan M. Alzheimers disease is not associated with the hypertension genetic risk factors PLA(2) or G protein beta3, either independently or interactively with apolipoprotein E. American Journal of Medical Genetics. 88: 465-8. PMID 10490699 DOI: 10.1002/(Sici)1096-8628(19991015)88:5<465::Aid-Ajmg5>3.0.Co;2-M |
0.539 |
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| 1999 |
Town T, Abdullah L, Crawford F, Schinka J, Ordorica PI, Francis E, Hughes P, Duara R, Mullan M. Association of a functional mu-opioid receptor allele (+118A) with alcohol dependency. American Journal of Medical Genetics. 88: 458-61. PMID 10490697 DOI: 10.1002/(Sici)1096-8628(19991015)88:5<458::Aid-Ajmg3>3.0.Co;2-S |
0.452 |
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| 1999 |
Crawford F, Freeman M, Town T, Fallin D, Gold M, Duara R, Mullan M. No genetic association between polymorphisms in the Tau gene and Alzheimer's disease in clinic or population based samples. Neuroscience Letters. 266: 193-6. PMID 10465706 DOI: 10.1016/S0304-3940(99)00303-1 |
0.54 |
|
| 1999 |
Crawford F, Town T, Freeman M, Schinka J, Gold M, Duara R, Mullan M. The alpha-2 macroglobulin gene is not associated with Alzheimer's disease in a case-control sample. Neuroscience Letters. 270: 133-6. PMID 10462112 DOI: 10.1016/S0304-3940(99)00470-X |
0.521 |
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| 1999 |
Tan J, Town T, Paris D, Placzek A, Parker T, Crawford F, Yu H, Humphrey J, Mullan M. Activation of microglial cells by the CD40 pathway: relevance to multiple sclerosis. Journal of Neuroimmunology. 97: 77-85. PMID 10408982 DOI: 10.1016/S0165-5728(99)00053-3 |
0.52 |
|
| 1999 |
Paris D, Town T, Parker TA, Tan J, Humphrey J, Crawford F, Mullan M. Inhibition of Alzheimer's beta-amyloid induced vasoactivity and proinflammatory response in microglia by a cGMP-dependent mechanism. Experimental Neurology. 157: 211-21. PMID 10222124 DOI: 10.1006/Exnr.1999.7055 |
0.575 |
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| 1998 |
Paris D, Town T, Parker TA, Humphrey J, Mullan M. Isoform-specific vasoconstriction induced by apolipoprotein E and modulation of this effect by Alzheimer's beta-amyloid peptide. Neuroscience Letters. 256: 73-6. PMID 9853706 DOI: 10.1016/S0304-3940(98)00764-2 |
0.565 |
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| 1998 |
Town T, Paris D, Fallin D, Duara R, Barker W, Gold M, Crawford F, Mullan M. The -491A/T apolipoprotein E promoter polymorphism association with Alzheimer's disease: independent risk and linkage disequilibrium with the known APOE polymorphism. Neuroscience Letters. 252: 95-8. PMID 9756330 DOI: 10.1016/S0304-3940(98)00567-9 |
0.503 |
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| 1998 |
Paris D, Parker TA, Town T, Suo Z, Fang C, Humphrey J, Crawford F, Mullan M. Role of peroxynitrite in the vasoactive and cytotoxic effects of Alzheimer's beta-amyloid1-40 peptide. Experimental Neurology. 152: 116-22. PMID 9682018 DOI: 10.1006/Exnr.1998.6828 |
0.57 |
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| 1997 |
Fallin D, Kundtz A, Town T, Gauntlett AC, Duara R, Barker W, Crawford F, Mullan M. No association between the low density lipoprotein receptor-related protein (LRP) gene and late-onset Alzheimer's disease in a community-based sample. Neuroscience Letters. 233: 145-7. PMID 9350853 DOI: 10.1016/S0304-3940(97)00634-4 |
0.537 |
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| 1997 |
Town T, Fallin D, Crawford F, Walsh S, Solomon R, Mullan M. Lack of association between the apolipoprotein E epsilon4 allele (APOE epsilon4) and chronic schizophrenia. American Journal of Medical Genetics. 74: 451-2. PMID 9259385 DOI: 10.1002/(Sici)1096-8628(19970725)74:4<451::Aid-Ajmg20>3.0.Co;2-G |
0.445 |
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