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Year Citation  Score
2024 Souza-Silva TG, Neves EGA, Koh C, Teixeira-Carvalho A, Araújo SS, Nunes MDCP, Gomes JAS, Gollob KJ, Dutra WO. Correlation of blood-based immune molecules with cardiac gene expression profiles reveals insights into Chagas cardiomyopathy pathogenesis. Frontiers in Immunology. 15: 1338582. PMID 38390336 DOI: 10.3389/fimmu.2024.1338582  0.619
2023 Koh CC, Gollob KJ, Dutra WO. Balancing the functions of DNA extracellular traps in intracellular parasite infections: implications for host defense, disease pathology and therapy. Cell Death & Disease. 14: 450. PMID 37474501 DOI: 10.1038/s41419-023-05994-8  0.607
2023 Neves EGA, Koh CC, Lucinda PPD, Souza-Silva TG, Medeiros NI, Pantaleão A, Mutarelli A, de Assis Silva Gomes J, de Araújo Silva S, Gollob KJ, do Carmo Pereira Nunes M, Dutra WO. Blocking activation of CD4CD8 T cells modulates their cytotoxic potential and decreases the expression of inflammatory and chemotactic receptors. Clinical Immunology (Orlando, Fla.). 109331. PMID 37088297 DOI: 10.1016/j.clim.2023.109331  0.664
2023 Koh CC, Neves EGA, de Souza-Silva TG, Carvalho AC, Pinto CHR, Galdino AS, Gollob KJ, Dutra WO. Cytokine Networks as Targets for Preventing and Controlling Chagas Heart Disease. Pathogens (Basel, Switzerland). 12. PMID 36839443 DOI: 10.3390/pathogens12020171  0.64
2023 Pignataro-Oshiro F, Figueiredo AB, Galdino NAL, Morais KLP, Dutra WO, Silva BGM, Feriani D, Abrantes FA, Silva ILAFE, Filho JS, Framil JVS, Cesca MG, Riechelmann RSP, Batista MV, Gollob KJ. Distinct systemic immune networks define severe . mild COVID-19 in hematologic and solid cancer patients. Frontiers in Immunology. 13: 1052104. PMID 36700209 DOI: 10.3389/fimmu.2022.1052104  0.588
2022 de Souza-Silva TG, Gollob KJ, Dutra WO. T-cell receptor variable region usage in Chagas disease: A systematic review of experimental and human studies. Plos Neglected Tropical Diseases. 16: e0010546. PMID 36107855 DOI: 10.1371/journal.pntd.0010546  0.651
2022 Magalhães LMD, Gollob KJ, Zingales B, Dutra WO. Pathogen diversity, immunity, and the fate of infections: lessons learned from Trypanosoma cruzi human-host interactions. The Lancet. Microbe. 3: e711-e722. PMID 36058233 DOI: 10.1016/S2666-5247(21)00265-2  0.607
2022 Barbosa CD, Canto FB, Gomes A, Brandao LM, Lima JR, Melo GA, Granato A, Neves EGA, Dutra WO, Oliveira AC, Nóbrega A, Bellio M. Cytotoxic CD4 T cells driven by T-cell intrinsic IL-18R/MyD88 signaling predominantly infiltrate -infected hearts. Elife. 11. PMID 35670567 DOI: 10.7554/eLife.74636  0.387
2022 Pinto BF, Medeiros NI, Teixeira-Carvalho A, Fiuza JA, Eloi-Santos SM, Nunes MCP, Silva SA, Fontes-Cal TCM, Belchior-Bezerra M, Dutra WO, Correa-Oliveira R, Gomes JAS. Modulation of Regulatory T Cells Activity by Distinct CD80 and CD86 Interactions With CD28/CTLA-4 in Chagas Cardiomyopathy. Frontiers in Cardiovascular Medicine. 9: 750876. PMID 35665256 DOI: 10.3389/fcvm.2022.750876  0.529
2022 Neves EGA, Koh CC, Souza-Silva TG, Passos LSA, Silva ACC, Velikkakam T, Villani F, Coelho JS, Brodskyn CI, Teixeira A, Gollob KJ, Nunes MDCP, Dutra WO. T-Cell Subpopulations Exhibit Distinct Recruitment Potential, Immunoregulatory Profile and Functional Characteristics in Chagas versus Idiopathic Dilated Cardiomyopathies. Frontiers in Cardiovascular Medicine. 9: 787423. PMID 35187122 DOI: 10.3389/fcvm.2022.787423  0.667
2021 Velikkakam T, Gollob KJ, Dutra WO. Double-negative T cells: setting the stage for disease control or progression. Immunology. PMID 34939192 DOI: 10.1111/imm.13441  0.665
2021 Passos LSA, Koh CC, Magalhães LMD, Nunes MDCP, Gollob KJ, Dutra WO. Distinct CD4CD8 (Double-Negative) Memory T-Cell Subpopulations Are Associated With Indeterminate and Cardiac Clinical Forms of Chagas Disease. Frontiers in Immunology. 12: 761795. PMID 34868005 DOI: 10.3389/fimmu.2021.761795  0.625
2021 Neves EGA, Koh CC, Padilha da Silva JL, Passos LSA, Villani FNA, Dos Santos JSC, Menezes CAS, Silva VR, Tormin JPAS, Evangelista GFB, Carvalho AT, Rocha MODC, Nascimento B, Gollob KJ, Nunes MDCP, ... Dutra WO, et al. Systemic cytokines, chemokines and growth factors reveal specific and shared immunological characteristics in infectious cardiomyopathies. Cytokine. 148: 155711. PMID 34592495 DOI: 10.1016/j.cyto.2021.155711  0.664
2021 Lanna MF, Resende LA, Aguiar-Soares RDO, de Miranda MB, de Mendonça LZ, Melo Júnior OAO, Mariano RMDS, Leite JC, Silveira P, Corrêa-Oliveira R, Dutra WO, Reis AB, Martins-Filho OA, de Moura SAL, Silveira-Lemos D, et al. Corrigendum: Kinetics of Phenotypic and Functional Changes in Mouse Models of Sponge Implants: Rational Selection to Optimize Protocols for Specific Biomolecules Screening Purposes. Frontiers in Bioengineering and Biotechnology. 9: 660117. PMID 33748096 DOI: 10.3389/fbioe.2021.660117  0.382
2021 Queiroz EA, Medeiros NI, Mattos RT, Pinto BF, Carvalho APM, Dutra WO, Félix-Lana FC, Correa-Oliveira R, Gomes JAS. CCL2 and IFN-γ serum levels as biomarker for subclinical infection in household contacts of leprosy patients. Microbial Pathogenesis. 104725. PMID 33400985 DOI: 10.1016/j.micpath.2020.104725  0.563
2020 Silva VR, Neves EGA, Passos LSA, Cristina de Melo F, Teixeira-Carvalho A, Nassif MCL, Junqueira LL, Aikawa E, Dutra WO, Nunes MCP. Decreased Cytokine Plasma Levels and Changes in T-Cell Activation Are Associated With Hemodynamic Improvement and Clinical Outcomes After Percutaneous Mitral Commissurotomy in Patients With Rheumatic Mitral Stenosis. Frontiers in Cardiovascular Medicine. 7: 604826. PMID 33614739 DOI: 10.3389/fcvm.2020.604826  0.306
2020 Lanna MF, Resende LA, Aguiar-Soares RDO, de Miranda MB, de Mendonça LZ, Melo Júnior OAO, Mariano RMDS, Leite JC, Silveira P, Corrêa-Oliveira R, Dutra WO, Reis AB, Martins-Filho OA, de Moura SAL, Silveira-Lemos D, et al. Kinetics of Phenotypic and Functional Changes in Mouse Models of Sponge Implants: Rational Selection to Optimize Protocols for Specific Biomolecules Screening Purposes. Frontiers in Bioengineering and Biotechnology. 8: 538203. PMID 33344427 DOI: 10.3389/fbioe.2020.538203  0.53
2020 Costa GC, Rocha MODC, Souza PEA, Melo DFS, Moreira PR, Gollob KJ, Nunes MDCP, Dutra WO. CD14 genotype and functional dichotomy of CD14+ and CD14- cells are associated with activated immune response and development of Chagas dilated cardiomyopathy. Memorias Do Instituto Oswaldo Cruz. 115: e200110. PMID 33146244 DOI: 10.1590/0074-02760200110  0.628
2020 Koh CC, Wardini AB, Vieira M, Passos LSA, Martinelli PM, Neves EGA, Antonelli LRDV, Barbosa DF, Velikkakam T, Gutseit E, Menezes GB, Giunchetti RC, Machado PRL, Carvalho EM, Gollob KJ, ... Dutra WO, et al. Human CD8+ T Cells Release Extracellular Traps Co-Localized With Cytotoxic Vesicles That Are Associated With Lesion Progression and Severity in Human Leishmaniasis. Frontiers in Immunology. 11: 594581. PMID 33117407 DOI: 10.3389/fimmu.2020.594581  0.636
2020 Castellucci LC, Almeida L, Cherlin S, Fakiola M, Francis RW, Carvalho EM, Santos da Hora A, do Lago TS, Figueiredo AB, Cavalcanti CM, Alves NS, Morais KLP, Teixeira-Carvalho A, Dutra WO, Gollob KJ, et al. A Genome-Wide Association Study Identifies SERPINB10, CRLF3, STX7, LAMP3, IFNG-AS1 and KRT80 As Risk Loci Contributing to Cutaneous Leishmaniasis In Brazil. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 32830257 DOI: 10.1093/cid/ciaa1230  0.509
2020 Koh CC, Wardini AB, Vieira M, Passos LSA, Martinelli PM, Neves EGA, Antonelli LRdV, Barbosa DF, Velikkakam T, Gutseit E, Menezes GB, Giunchetti RC, Machado PRL, Carvalho EM, Gollob KJ, ... Dutra WO, et al. Human CD8+ T Cells Release Extracellular Traps Co-Localized With Cytotoxic Vesicles That Are Associated With Lesion Progression and Severity in Human Leishmaniasis Frontiers in Immunology. 11. DOI: 10.3389/fimmu.2020.594581  0.606
2020 Santos JA, Nascimento BR, Nunes MC, Brandão-de-Resende C, Beaton AZ, Ribeiro AL, Oliveira KK, Franco J, Fraga CL, Costa WAA, Macedo FV, Filho DSGF, Sable CA, Dutra WO. GENOTYPIC AND PHENOTYPIC EXPRESSION OF IL2G/T AND IL-8 HELP PREDICT ESTABLISHMENT OF CLINICAL RHEUMATIC HEART DISEASE: DATA FROM THE PROVAR STUDY Journal of the American College of Cardiology. 75: 3629. DOI: 10.1016/s0735-1097(20)34256-x  0.305
2019 Santos MAXO, Castro HHO, Magalhães LMD, Dutra WO, Gollob KJ, Guimarães NR, Magalhães PP, de Macêdo Farias L, Horta MCR, Souza PEA. Resinous adhesive systems differentially affect the expression of cytokines by human monocytes stimulated or not with Streptococcus mutans in vitro. Archives of Oral Biology. 111: 104641. PMID 31927406 DOI: 10.1016/j.archoralbio.2019.104641  0.585
2019 Medeiros NI, Gomes JAS, Fiuza JA, Sousa GR, Almeida EF, Novaes RO, Rocha VLS, Chaves AT, Dutra WO, Rocha MOC, Correa-Oliveira R. MMP-2 and MMP-9 plasma levels are potential biomarkers for indeterminate and cardiac clinical forms progression in chronic Chagas disease. Scientific Reports. 9: 14170. PMID 31578449 DOI: 10.1038/S41598-019-50791-Z  0.439
2019 Temponi EF, Souza PEA, Souto GR, Magalhães LMD, Dutra WO, Gollob KJ, Silva TA, Soares RV. Effect of porous tantalum on the biological response of human peripheral mononuclear cells exposed to Porphyromonas gingivalis. Journal of Investigative and Clinical Dentistry. e12472. PMID 31560456 DOI: 10.1111/jicd.12472  0.568
2019 Magalhães LMD, Passos LSA, Chiari E, Galvão LMC, Koh CC, Rodrigues-Alves ML, Giunchetti RC, Gollob K, Dutra WO. Co-infection with distinct Trypanosoma cruzi strains induces an activated immune response in human monocytes. Parasite Immunology. PMID 31494949 DOI: 10.1111/Pim.12668  0.596
2019 Rodrigues de Faria D, Barbieri LC, Koh CC, Lima Machado PR, Barreto CC, Figueiredo de Lima CM, Lessa MM, Carvalho E, Gollob KJ, Dutra WO. In Situ Cellular Response Underlying Successful Treatment of Mucosal Leishmaniasis with a Combination of Pentavalent Antimonial and Pentoxifylline. The American Journal of Tropical Medicine and Hygiene. PMID 31219000 DOI: 10.4269/ajtmh.19-0139  0.612
2019 Viana AG, Magalhães LMD, Giunchetti RC, Dutra WO, Gollob KJ. Leishmania infantum induces expression of the negative regulatory checkpoint, CTLA-4, by human naïve CD8 T cells. Parasite Immunology. 41: e12659. PMID 31173374 DOI: 10.1111/pim.12659  0.65
2019 Neves SO, Magalhães LMD, Corrêa JD, Dutra WO, Gollob KJ, Silva TA, Horta MCR, Souza PEA. Composite-derived monomers affect cell viability and cytokine expression in human leukocytes stimulated with Porphyromonas gingivalis. Journal of Applied Oral Science : Revista Fob. 27: e20180529. PMID 31166413 DOI: 10.1590/1678-7757-2018-0529  0.613
2019 Queiroz EA, Medeiros NI, Mattos RT, Carvalho APM, Rodrigues-Alves ML, Dutra WO, Félix-Lana FC, Gomes JAS, Correa-Oliveira R. Immunological biomarkers of subclinical infection in household contacts of leprosy patients. Immunobiology. 224: 518-525. PMID 31109749 DOI: 10.1016/J.Imbio.2019.05.002  0.559
2019 Diamantino Soares AC, Araújo Passos LS, Sable C, Beaton A, Ribeiro VT, Gollob KJ, Dutra WO, Nunes MCP. Circulating cytokines predict severity of rheumatic heart disease. International Journal of Cardiology. PMID 31079974 DOI: 10.1016/j.ijcard.2019.04.063  0.6
2019 Medeiros NI, Pinto BF, Elói-Santos SM, Teixeira-Carvalho A, Magalhães LMD, Dutra WO, Correa-Oliveira R, Gomes JAS. Evidence of Different IL-1β Activation Pathways in Innate Immune Cells From Indeterminate and Cardiac Patients With Chronic Chagas Disease. Frontiers in Immunology. 10: 800. PMID 31057540 DOI: 10.3389/Fimmu.2019.00800  0.523
2019 Passos LSA, Magalhães LMD, Soares RP, Marques AF, Alves MLR, Giunchetti RC, Nunes MDCP, Gollob KJ, Dutra WO. Corrigendum: Activation of Human CD11b B1 B-Cells by -Derived Proteins Is Associated With Protective Immune Response in Human Chagas Disease. Frontiers in Immunology. 10: 367. PMID 30891038 DOI: 10.3389/fimmu.2019.00367  0.588
2019 Damasio MPS, Rocha MOC, Sousa GR, Ferreira KS, Valente VAA, Araujo FF, Medeiros NI, Chaves AT, Dutra WO, Correa-Oliveira R, Gomes JAS. PD1 and PDL1 molecules control suppressor activity of regulatory T cells in chronic Chagas cardiomyopathy patients. Human Immunology. PMID 30853363 DOI: 10.1016/J.Humimm.2019.03.009  0.58
2018 Passos LSA, Magalhães LMD, Soares RP, Marques AF, Alves MLR, Giunchetti RC, Nunes MDCP, Gollob KJ, Dutra WO. Activation of Human CD11b B1 B-Cells by -Derived Proteins Is Associated With Protective Immune Response in Human Chagas Disease. Frontiers in Immunology. 9: 3015. PMID 30662439 DOI: 10.3389/fimmu.2018.03015  0.623
2018 Martins GC, de Oliveira Melo Júnior OA, Botoni LS, Nogueira MM, da Costa Val AP, Blanco BS, Dutra WO, Giunchetti RC, Melo MM, da Silveira Lemos D. Clinical-pathological and immunological biomarkers in dogs with atopic dermatitis. Veterinary Immunology and Immunopathology. 205: 58-64. PMID 30459002 DOI: 10.1016/j.vetimm.2018.10.009  0.351
2018 Pinto BF, Medeiros NI, Fontes-Cal TCM, Naziazeno IM, Correa-Oliveira R, Dutra WO, Gomes JAS. The Role of Co-Stimulatory Molecules in Chagas Disease. Cells. 7. PMID 30405039 DOI: 10.3390/cells7110200  0.537
2018 Pereira FB, Dutra WO, Gollob KJ, Reis EA, Oliveira ALG, Rocha MODC, Menezes CADS. Vasoactive intestinal peptide degradation might influence Interleukin-17 expression in cardiac chagasic patients. Revista Do Instituto De Medicina Tropical De Sao Paulo. 60: e57. PMID 30365640 DOI: 10.1590/S1678-9946201860057  0.608
2018 Dutra WO, Barbosa DF, de Souza PEA, Morgan D, Poetker S, Guimarães LH, Bacelar O, Gollob KJ, Carvalho EM. A Th-2-type response is associated with exuberant lesions in pregnant women infected with Leishmania braziliensis. The Journal of Infectious Diseases. PMID 30165577 DOI: 10.1093/infdis/jiy510  0.552
2018 Pinto BF, Medeiros NI, Teixeira-Carvalho A, Eloi-Santos SM, Fontes-Cal TCM, Rocha DA, Dutra WO, Correa-Oliveira R, Gomes JAS. CD86 Expression by Monocytes Influences an Immunomodulatory Profile in Asymptomatic Patients with Chronic Chagas Disease. Frontiers in Immunology. 9: 454. PMID 29599775 DOI: 10.3389/Fimmu.2018.00454  0.585
2018 Araújo LRA, Santos MAXO, Magalhães LMD, Dutra WO, Gollob KJ, Guimarães NR, Farias LM, Horta MCR, Souza PEA. Efeito de Sistemas Adesivos Contemporâneos na Produção de Citocinas por Monócitos Estimulados por Streptococcus Mutans Journal of Health Sciences. 19: 149. DOI: 10.17921/2447-8938.2017v19n5p149  0.579
2017 Viana AG, Magalhães LMD, Giunchetti RC, Dutra WO, Gollob KJ. Infection of Human Monocytes with Strains Induces a Downmodulated Response when Compared with Infection with . Frontiers in Immunology. 8: 1896. PMID 29358935 DOI: 10.3389/fimmu.2017.01896  0.609
2017 Magalhães LMD, Viana A, de Jesus AC, Chiari E, Galvão L, Gomes JA, Gollob KJ, Dutra WO. Distinct Trypanosoma cruzi isolates induce activation and apoptosis of human neutrophils. Plos One. 12: e0188083. PMID 29176759 DOI: 10.1371/journal.pone.0188083  0.631
2017 Medeiros NI, Mattos RT, Menezes CA, Fares RCG, Talvani A, Dutra WO, Rios-Santos F, Correa-Oliveira R, Gomes JAS. IL-10 and TGF-β unbalanced levels in neutrophils contribute to increase inflammatory cytokine expression in childhood obesity. European Journal of Nutrition. PMID 28735358 DOI: 10.1007/S00394-017-1515-Y  0.487
2017 Passos LSA, Magalhães LMD, Soares RP, Marques AF, Nunes MDCP, Gollob KJ, Dutra WO. Specific activation of CD4(-) CD8(-) double-negative T cells by Trypanosoma cruzi-derived glycolipids induces a proinflammatory profile associated with cardiomyopathy in Chagas patients. Clinical and Experimental Immunology. PMID 28543170 DOI: 10.1111/cei.12992  0.685
2017 Santos MB, de Oliveira DT, Cazzaniga RA, Varjão CS, Santos PLD, Santos MLB, Correia CB, Faria DR, Simon MDV, Silva JS, Dutra WO, Reed SG, Duthie MS, de Almeida RP, de Jesus AR. Distinct Roles of Th17 and Th1 Cells in Inflammatory Responses Associated with the Presentation of Paucibacillary Leprosy and Leprosy Reactions Th17 Immune Response in Leprosy. Scandinavian Journal of Immunology. PMID 28426172 DOI: 10.1111/Sji.12558  0.357
2017 Cordeiro CA, Vieira EL, Castro VM, Dutra WO, Costa RA, Orefice JL, Campos WR, Orefice F, Young LH, Teixeira AL. T cell Immunoregulation in Active Ocular Toxoplasmosis. Immunology Letters. PMID 28214536 DOI: 10.1016/j.imlet.2017.02.009  0.418
2017 Medeiros NI, Fares RC, Franco EP, Sousa GR, Mattos RT, Chaves AT, Nunes MD, Dutra WO, Correa-Oliveira R, Rocha MO, Gomes JA. Differential Expression of Matrix Metalloproteinases 2, 9 and Cytokines by Neutrophils and Monocytes in the Clinical Forms of Chagas Disease. Plos Neglected Tropical Diseases. 11: e0005284. PMID 28118356 DOI: 10.1371/Journal.Pntd.0005284  0.53
2017 Horta M, Yamauti M, Sa T, Lima M, Magalhaes L, Dutra W, Gollob K, Moreira A, Magalhaes C, Souza P. Dental resins affect differently the expression of chemokines and chemokine-receptors Dental Materials. 33: e84. DOI: 10.1016/j.dental.2017.08.169  0.538
2016 Mattos RT, Medeiros NI, Menezes CA, Fares RC, Franco EP, Dutra WO, Rios-Santos F, Correa-Oliveira R, Gomes JA. Chronic Low-Grade Inflammation in Childhood Obesity Is Associated with Decreased IL-10 Expression by Monocyte Subsets. Plos One. 11: e0168610. PMID 27977792 DOI: 10.1371/Journal.Pone.0168610  0.536
2016 de Mendonça LZ, Resende LA, Lanna MF, Aguiar-Soares RD, Roatt BM, Castro RA, Batista MA, Silveira-Lemos D, Gomes Jde A, Fujiwara RT, Rezende SA, Martins-Filho OA, Corrêa-Oliveira R, Dutra WO, Reis AB, et al. Multicomponent LBSap vaccine displays immunological and parasitological profiles similar to those of Leish-Tec® and Leishmune® vaccines against visceral leishmaniasis. Parasites & Vectors. 9: 472. PMID 27577735 DOI: 10.1186/S13071-016-1752-6  0.383
2016 de Assis Gonzaga F, de Miranda TT, Magalhães LM, Dutra WO, Gollob KJ, Souza PE, Horta MC. Effects of Bio-Oss® and Cerasorb(®) dental M on the expression of bone-remodeling mediators in human monocytes. Journal of Biomedical Materials Research. Part B, Applied Biomaterials. PMID 27401453 DOI: 10.1002/jbm.b.33747  0.618
2016 Passos LS, Villani FN, Magalhães LM, Gollob KJ, Antonelli LR, Nunes MC, Dutra WO. Blocking of CD1d Decreases Trypanosoma cruzi-Induced Activation of CD4-CD8- T Cells and Modulates the Inflammatory Response in Patients With Chagas Heart Disease. The Journal of Infectious Diseases. 214: 935-44. PMID 27368347 DOI: 10.1093/infdis/jiw266  0.688
2016 Viana KF, Fiuza JA, Gannavaram S, Dey R, Selvapandiyan A, Bartholomeu DC, Silveira-Lemos Dd, Bueno LL, Dutra WO, Fujiwara RT, Nakhasi HL, Giunchetti RC. Application of rapid in vitro co-culture system of macrophages and T-cell subsets to assess the immunogenicity of dogs vaccinated with live attenuated Leishmania donovani centrin deleted parasites (LdCen(-/-)). Parasites & Vectors. 9: 250. PMID 27136900 DOI: 10.1186/s13071-016-1528-z  0.302
2016 Torres KC, Rocha NP, de Rezende VB, Dutra WO, Gollob KJ, Cardoso F, Teixeira AL. Persistent Sydenham's chorea is not associated with sustained lymphocyte dysfunction. Arquivos De Neuro-Psiquiatria. 74: 5-9. PMID 26486494 DOI: 10.1590/0004-282X20150179  0.6
2016 Torres KCdL, Rocha NP, de Rezende VB, Dutra WO, Gollob KJ, Cardoso F, Teixeira AL. Persistent Sydenham’s chorea is not associated with sustained lymphocyte dysfunction | A coreia de Sydenham persistente não está associada à disfunção sustentada de linfócitos Arquivos De Neuro-Psiquiatria. 74: 5-9. DOI: 10.1590/0004-282X20150179  0.561
2015 Magalhães LM, Viana A, Chiari E, Galvão LM, Gollob KJ, Dutra WO. Differential Activation of Human Monocytes and Lymphocytes by Distinct Strains of Trypanosoma cruzi. Plos Neglected Tropical Diseases. 9: e0003816. PMID 26147698 DOI: 10.1371/journal.pntd.0003816  0.577
2015 Viana KF, Aguiar-Soares RD, Ker HG, Resende LA, Souza-Fagundes EM, Dutra WO, Fujiwara RT, da Silveira-Lemos D, Sant'Ana Rde C, Wardini AB, Araújo MS, Martins-Filho OA, Reis AB, Giunchetti RC. Setting the proportion of CD4+ and CD8+ T-cells co-cultured with canine macrophages infected with Leishmania chagasi. Veterinary Parasitology. 211: 124-32. PMID 26095951 DOI: 10.1016/j.vetpar.2015.05.025  0.357
2014 Andrade DV, Gollob KJ, Dutra WO. Acute chagas disease: new global challenges for an old neglected disease. Plos Neglected Tropical Diseases. 8: e3010. PMID 25077613 DOI: 10.1371/journal.pntd.0003010  0.583
2014 Dutra WO, Menezes CA, Magalhães LM, Gollob KJ. Immunoregulatory networks in human Chagas disease. Parasite Immunology. 36: 377-87. PMID 24611805 DOI: 10.1111/pim.12107  0.666
2014 Gollob KJ, Viana AG, Dutra WO. Immunoregulation in human American leishmaniasis: balancing pathology and protection. Parasite Immunology. 36: 367-76. PMID 24471648 DOI: 10.1111/pim.12100  0.617
2013 Corrêa MV, da Costa Rocha MO, de Sousa GR, do Carmo Pereira Nunes M, Gollob KJ, Dutra WO, da Silva Menezes CA. Low levels of vasoactive intestinal peptide are associated with Chagas disease cardiomyopathy. Human Immunology. 74: 1375-81. PMID 23800435 DOI: 10.1016/j.humimm.2013.06.028  0.621
2013 Saraiva AM, de Fátima Correia Silva J, Alves e Silva MR, da Costa JE, Gollob KJ, Moreira PR, Dutra WO. Transcription factor STAT1 gene polymorphism is associated with the development of severe forms of periodontal disease. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 62: 551-4. PMID 23609054 DOI: 10.1007/s00011-013-0622-3  0.587
2013 Magalhães LM, Villani FN, Nunes Mdo C, Gollob KJ, Rocha MO, Dutra WO. High interleukin 17 expression is correlated with better cardiac function in human Chagas disease. The Journal of Infectious Diseases. 207: 661-5. PMID 23204182 DOI: 10.1093/infdis/jis724  0.634
2013 Saraiva AM, Alves e Silva MR, Correia Silva Jde F, da Costa JE, Gollob KJ, Dutra WO, Moreira PR. Evaluation of IL17A expression and of IL17A, IL17F and IL23R gene polymorphisms in Brazilian individuals with periodontitis. Human Immunology. 74: 207-14. PMID 23137879 DOI: 10.1016/j.humimm.2012.10.026  0.62
2012 e Silva MR, Moreira PR, da Costa GC, Saraiva AM, de Souza PE, Amormino SA, da Costa JE, Gollob KJ, Dutra WO. Association of CD28 and CTLA-4 gene polymorphisms with aggressive periodontitis in Brazilians. Oral Diseases. 19: 568-76. PMID 23163888 DOI: 10.1111/Odi.12036  0.605
2012 Machado FS, Dutra WO, Esper L, Gollob KJ, Teixeira MM, Factor SM, Weiss LM, Nagajyothi F, Tanowitz HB, Garg NJ. Current understanding of immunity to Trypanosoma cruzi infection and pathogenesis of Chagas disease. Seminars in Immunopathology. 34: 753-70. PMID 23076807 DOI: 10.1007/S00281-012-0351-7  0.651
2012 Menezes CA, Sullivan AK, Falta MT, Mack DG, Freed BM, Rocha MO, Gollob KJ, Fontenot AP, Dutra WO. Highly conserved CDR3 region in circulating CD4(+)Vβ5(+) T cells may be associated with cytotoxic activity in Chagas disease. Clinical and Experimental Immunology. 169: 109-18. PMID 22774985 DOI: 10.1111/j.1365-2249.2012.04608.x  0.664
2011 Dutra WO, de Faria DR, Lima Machado PR, Guimarães LH, Schriefer A, Carvalho E, Gollob KJ. Immunoregulatory and Effector Activities in Human Cutaneous and Mucosal Leishmaniasis: Understanding Mechanisms of Pathology. Drug Development Research. 72: 430-436. PMID 23504276 DOI: 10.1002/ddr.20449  0.634
2011 Menezes C, Costa GC, Gollob KJ, Dutra WO. Clinical aspects of Chagas disease and implications for novel therapies. Drug Development Research. 72: 471-479. PMID 22267887 DOI: 10.1002/ddr.20454  0.592
2011 Keesen TS, Antonelli LR, Faria DR, Guimarães LH, Bacellar O, Carvalho EM, Dutra WO, Gollob KJ. CD4(+) T cells defined by their Vβ T cell receptor expression are associated with immunoregulatory profiles and lesion size in human leishmaniasis. Clinical and Experimental Immunology. 165: 338-51. PMID 21726211 DOI: 10.1111/j.1365-2249.2011.04430.x  0.668
2011 Lima PM, Souza PE, Costa JE, Gomez RS, Gollob KJ, Dutra WO. Aggressive and chronic periodontitis correlate with distinct cellular sources of key immunoregulatory cytokines. Journal of Periodontology. 82: 86-95. PMID 20809862 DOI: 10.1902/jop.2010.100248  0.599
2011 Dutra WO, Gollob KJ. Neglected diseases: in need of bare necessities and breakthroughs Drug Development Research. 72: 427-429. DOI: 10.1002/ddr.20448  0.569
2010 Villani FN, Rocha MO, Nunes Mdo C, Antonelli LR, Magalhães LM, dos Santos JS, Gollob KJ, Dutra WO. Trypanosoma cruzi-induced activation of functionally distinct αβ and γδ CD4- CD8- T cells in individuals with polar forms of Chagas' disease. Infection and Immunity. 78: 4421-30. PMID 20696836 DOI: 10.1128/IAI.00179-10  0.694
2010 Torres KC, Dutra WO, de Rezende VB, Cardoso F, Gollob KJ, Teixeira AL. Monocyte dysfunction in Sydenham's chorea patients. Human Immunology. 71: 351-4. PMID 20080141 DOI: 10.1016/j.humimm.2010.01.007  0.612
2009 Moreira PR, Costa JE, Gomez RS, Gollob KJ, Dutra WO. TNFA and IL10 gene polymorphisms are not associated with periodontitis in Brazilians. The Open Dentistry Journal. 3: 184-90. PMID 19771178 DOI: 10.2174/1874210600903010184  0.611
2009 Dutra WO, Menezes CA, Villani FN, da Costa GC, da Silveira AB, Reis Dd, Gollob KJ. Cellular and genetic mechanisms involved in the generation of protective and pathogenic immune responses in human Chagas disease. Memorias Do Instituto Oswaldo Cruz. 104: 208-18. PMID 19753476 DOI: 10.1590/s0074-02762009000900027  0.61
2009 Faria DR, Souza PE, Durães FV, Carvalho EM, Gollob KJ, Machado PR, Dutra WO. Recruitment of CD8(+) T cells expressing granzyme A is associated with lesion progression in human cutaneous leishmaniasis. Parasite Immunology. 31: 432-9. PMID 19646207 DOI: 10.1111/j.1365-3024.2009.01125.x  0.609
2009 Dutra WO, Moreira PR, Souza PE, Gollob KJ, Gomez RS. Implications of cytokine gene polymorphisms on the orchestration of the immune response: lessons learned from oral diseases. Cytokine & Growth Factor Reviews. 20: 223-32. PMID 19502097 DOI: 10.1016/j.cytogfr.2009.05.005  0.601
2009 Bacellar O, Faria D, Nascimento M, Cardoso TM, Gollob KJ, Dutra WO, Scott P, Carvalho EM. Interleukin 17 production among patients with American cutaneous leishmaniasis. The Journal of Infectious Diseases. 200: 75-8. PMID 19476435 DOI: 10.1086/599380  0.627
2009 Costa GC, da Costa Rocha MO, Moreira PR, Menezes CA, Silva MR, Gollob KJ, Dutra WO. Functional IL-10 gene polymorphism is associated with Chagas disease cardiomyopathy. The Journal of Infectious Diseases. 199: 451-4. PMID 19099482 DOI: 10.1086/596061  0.619
2008 Gollob KJ, Antonelli LR, Faria DR, Keesen TS, Dutra WO. Immunoregulatory mechanisms and CD4-CD8- (double negative) T cell subpopulations in human cutaneous leishmaniasis: a balancing act between protection and pathology. International Immunopharmacology. 8: 1338-43. PMID 18687296 DOI: 10.1016/j.intimp.2008.03.016  0.659
2008 Dutra WO, Gollob KJ. Current concepts in immunoregulation and pathology of human Chagas disease. Current Opinion in Infectious Diseases. 21: 287-92. PMID 18448974 DOI: 10.1097/QCO.0b013e3282f88b80  0.598
2007 Nagib PR, Dutra WO, Chiari E, Machado CR. Trypanosoma cruzi: populations bearing opposite virulence induce differential expansion of circulating CD3+CD4-CD8- T cells and cytokine serum levels in young and adult rats. Experimental Parasitology. 116: 366-74. PMID 17399706 DOI: 10.1016/j.exppara.2007.02.003  0.322
2007 Souza PE, Rocha MO, Menezes CA, Coelho JS, Chaves AC, Gollob KJ, Dutra WO. Trypanosoma cruzi infection induces differential modulation of costimulatory molecules and cytokines by monocytes and T cells from patients with indeterminate and cardiac Chagas' disease. Infection and Immunity. 75: 1886-94. PMID 17283096 DOI: 10.1128/IAI.01931-06  0.688
2007 Moreira PR, Costa JE, Gomez RS, Gollob KJ, Dutra WO. The IL1A (-889) gene polymorphism is associated with chronic periodontal disease in a sample of Brazilian individuals. Journal of Periodontal Research. 42: 23-30. PMID 17214636 DOI: 10.1111/J.1600-0765.2006.00910.X  0.605
2006 Antonelli LR, Dutra WO, Oliveira RR, Torres KC, Guimarães LH, Bacellar O, Gollob KJ. Disparate immunoregulatory potentials for double-negative (CD4- CD8-) alpha beta and gamma delta T cells from human patients with cutaneous leishmaniasis. Infection and Immunity. 74: 6317-23. PMID 16923794 DOI: 10.1128/IAI.00890-06  0.653
2005 Faria DR, Gollob KJ, Barbosa J, Schriefer A, Machado PR, Lessa H, Carvalho LP, Romano-Silva MA, de Jesus AR, Carvalho EM, Dutra WO. Decreased in situ expression of interleukin-10 receptor is correlated with the exacerbated inflammatory and cytotoxic responses observed in mucosal leishmaniasis. Infection and Immunity. 73: 7853-9. PMID 16299275 DOI: 10.1128/Iai.73.12.7853-7859.2005  0.66
2005 Antonelli LR, Dutra WO, Almeida RP, Bacellar O, Carvalho EM, Gollob KJ. Activated inflammatory T cells correlate with lesion size in human cutaneous leishmaniasis. Immunology Letters. 101: 226-30. PMID 16083969 DOI: 10.1016/j.imlet.2005.06.004  0.647
2005 Torres KC, Antonelli LR, Souza AL, Teixeira MM, Dutra WO, Gollob KJ. Norepinephrine, dopamine and dexamethasone modulate discrete leukocyte subpopulations and cytokine profiles from human PBMC. Journal of Neuroimmunology. 166: 144-57. PMID 16026859 DOI: 10.1016/j.jneuroim.2005.06.006  0.589
2005 Gollob KJ, Antonelli LR, Dutra WO. Insights into CD4+ memory T cells following Leishmania infection. Trends in Parasitology. 21: 347-50. PMID 15967724 DOI: 10.1016/j.pt.2005.06.007  0.609
2005 Moreira PR, de Sá AR, Xavier GM, Costa JE, Gomez RS, Gollob KJ, Dutra WO. A functional interleukin-1 beta gene polymorphism is associated with chronic periodontitis in a sample of Brazilian individuals. Journal of Periodontal Research. 40: 306-11. PMID 15966908 DOI: 10.1111/j.1600-0765.2005.00801.x  0.616
2005 Carvalho LP, Passos S, Dutra WO, Soto M, Alonso C, Gollob KJ, Carvalho EM, Ribeiro de Jesus A. Effect of LACK and KMP11 on IFN-gamma production by peripheral blood mononuclear cells from cutaneous and mucosal leishmaniasis patients. Scandinavian Journal of Immunology. 61: 337-42. PMID 15853916 DOI: 10.1111/j.1365-3083.2005.01581.x  0.612
2005 de Souza PE, Gomez RS, Xavier GM, dos Santos JS, Gollob KJ, Dutra WO. Systemic leukocyte activation in patients with central giant cell lesions. Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. 34: 312-7. PMID 15817076 DOI: 10.1111/j.1600-0714.2004.00276.x  0.563
2005 Porto AF, Santos SB, Muniz AL, Basílio V, Rodrigues W, Neva FA, Dutra WO, Gollob KJ, Jacobson S, Carvalho EM. Helminthic infection down-regulates type 1 immune responses in human T cell lymphotropic virus type 1 (HTLV-1) carriers and is more prevalent in HTLV-1 carriers than in patients with HTLV-1-associated myelopathy/tropical spastic paraparesis Journal of Infectious Diseases. 191: 612-618. PMID 15655786 DOI: 10.1086/427560  0.663
2004 Torres KC, Dutra WO, Gollob KJ. Endogenous IL-4 and IFN-gamma are essential for expression of Th2, but not Th1 cytokine message during the early differentiation of human CD4+ T helper cells. Human Immunology. 65: 1328-35. PMID 15556683 DOI: 10.1016/j.humimm.2004.06.007  0.653
2004 Souza PE, Rocha MO, Rocha-Vieira E, Menezes CA, Chaves AC, Gollob KJ, Dutra WO. Monocytes from patients with indeterminate and cardiac forms of Chagas' disease display distinct phenotypic and functional characteristics associated with morbidity. Infection and Immunity. 72: 5283-91. PMID 15322024 DOI: 10.1128/IAI.72.9.5283-5291.2004  0.69
2004 Menezes CA, Rocha MO, Souza PE, Chaves AC, Gollob KJ, Dutra WO. Phenotypic and functional characteristics of CD28+ and CD28- cells from chagasic patients: distinct repertoire and cytokine expression. Clinical and Experimental Immunology. 137: 129-38. PMID 15196253 DOI: 10.1111/j.1365-2249.2004.02479.x  0.645
2004 Antonelli LR, Dutra WO, Almeida RP, Bacellar O, Gollob KJ. Antigen specific correlations of cellular immune responses in human leishmaniasis suggests mechanisms for immunoregulation. Clinical and Experimental Immunology. 136: 341-8. PMID 15086400 DOI: 10.1111/j.1365-2249.2004.02426.x  0.683
2004 Santos SB, Porto AF, Muniz AL, de Jesus AR, Magalhães E, Melo A, Dutra WO, Gollob KJ, Carvalho EM. Exacerbated inflammatory cellular immune response characteristics of HAM/TSP is observed in a large proportion of HTLV-I asymptomatic carriers. Bmc Infectious Diseases. 4: 7. PMID 15070424 DOI: 10.1186/1471-2334-4-7  0.641
2003 Costa RP, Gollob KJ, Machado PR, Bacellar OA, Almeida RP, Barral A, Barral-Netto M, Carvalho EM, Dutra WO. Adhesion molecule expression patterns indicate activation and recruitment of CD4+ T cells from the lymph node to the peripheral blood of early cutaneous leishmaniasis patients. Immunology Letters. 90: 155-9. PMID 14687718 DOI: 10.1016/J.Imlet.2003.09.001  0.619
2003 Rocha-Vieira E, Ferreira E, Vianna P, De Faria DR, Gaze ST, Dutra WO, Gollob KJ. Histopathological outcome of Leishmania major-infected BALB/c mice is improved by oral treatment with N-acetyl-l-cysteine. Immunology. 108: 401-8. PMID 12603607 DOI: 10.1046/j.1365-2567.2003.01582.x  0.575
2002 Bacellar O, Lessa H, Schriefer A, Machado P, Ribeiro de Jesus A, Dutra WO, Gollob KJ, Carvalho EM. Up-regulation of Th1-type responses in mucosal leishmaniasis patients. Infection and Immunity. 70: 6734-40. PMID 12438348 DOI: 10.1128/iai.70.12.6734-6740.2002  0.642
2002 Dutra WO, Correa-Oliveira R, Dunne D, Cecchini LF, Fraga L, Roberts M, Soares-Silveira AM, Webster M, Yssel H, Gollob KJ. Polarized Th2 like cells, in the absence of Th0 cells, are responsible for lymphocyte produced IL-4 in high IgE-producer schistosomiasis patients. Bmc Immunology. 3: 8. PMID 12100735 DOI: 10.1186/1471-2172-3-8  0.709
2001 Bottrel RL, Dutra WO, Martins FA, Gontijo B, Carvalho E, Barral-Netto M, Barral A, Almeida RP, Mayrink W, Locksley R, Gollob KJ. Flow cytometric determination of cellular sources and frequencies of key cytokine-producing lymphocytes directed against recombinant LACK and soluble Leishmania antigen in human cutaneous leishmaniasis. Infection and Immunity. 69: 3232-9. PMID 11292745 DOI: 10.1128/Iai.69.5.3232-3239.2001  0.678
1997 Martins-Filho OA, Dutra WO, Freeman GL, Silveira AM, Rabello A, Colley DG, Prata A, Gazzinelli G, Correa-Oliveira R, Carvalho-Parra J. Flow cytometric study of blood leucocytes in clinical forms of human schistosomiasis. Scandinavian Journal of Immunology. 46: 304-11. PMID 9315121 DOI: 10.1046/J.1365-3083.1997.D01-119.X  0.573
1997 Dutra WO, Gollob KJ, Pinto-Dias JC, Gazzinelli G, Correa-Oliveira R, Coffman RL, Carvalho-Parra JF. Cytokine mRNA profile of peripheral blood mononuclear cells isolated from individuals with Trypanosoma cruzi chronic infection. Scandinavian Journal of Immunology. 45: 74-80. PMID 9010503 DOI: 10.1046/J.1365-3083.1997.D01-362.X  0.769
1996 Gollob KJ, Dutra WO, Coffman RL. Early message expression of interleukin-4 and interferon-gamma, but not of interleukin-2 and interleukin-10, reflects later polarization of primary CD4+ T cell cultures. European Journal of Immunology. 26: 1565-70. PMID 8766562 DOI: 10.1002/Eji.1830260724  0.712
1996 Dutra WO, Martins-Filho OA, Cançado JR, Pinto-Dias JC, Brener Z, Gazzinelli G, Carvalho JF, Colley DG. Chagasic patients lack CD28 expression on many of their circulating T lymphocytes. Scandinavian Journal of Immunology. 43: 88-93. PMID 8560201  0.348
1994 Dutra WO, Martins-Filho OA, Cancado JR, Pinto-Dias JC, Brener Z, Freeman GL, Colley DG, Gazzinelli G, Parra JC. Activated T and B lymphocytes in peripheral blood of patients with Chagas' disease International Immunology. 6: 499-506. PMID 8018591  0.353
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