| Year |
Citation |
Score |
| 2023 |
Yuan S, Xia L, Wang C, Wu F, Zhang B, Pan C, Fan Z, Lei X, Stevens RC, Sali A, Sun L, Shui W. Conformational Dynamics of the Activated GLP-1 Receptor-G Complex Revealed by Cross-Linking Mass Spectrometry and Integrative Structure Modeling. Acs Central Science. 9: 992-1007. PMID 37252352 DOI: 10.1021/acscentsci.3c00063 |
0.34 |
|
| 2023 |
Li W, Li A, Yu B, Zhang X, Liu X, White K, Stevens R, Baumeister W, Sali A, Jasnin M, Sun L. In situ structure of actin remodeling during glucose-stimulated insulin secretion using cryo-electron tomography. Research Square. PMID 37066286 DOI: 10.21203/rs.3.rs-2694866/v1 |
0.479 |
|
| 2023 |
Yang Y, Kang HJ, Gao R, Wang J, Han GW, DiBerto JF, Wu L, Tong J, Qu L, Wu Y, Pileski R, Li X, Zhang XC, Zhao S, Kenakin T, ... ... Stevens RC, et al. Structural insights into the human niacin receptor HCA2-G signalling complex. Nature Communications. 14: 1692. PMID 36973264 DOI: 10.1038/s41467-023-37177-6 |
0.36 |
|
| 2022 |
Li A, Zhang S, Loconte V, Liu Y, Ekman A, Thompson GJ, Sali A, Stevens RC, White K, Singla J, Sun L. An intensity-based post-processing tool for 3D instance segmentation of organelles in soft X-ray tomograms. Plos One. 17: e0269887. PMID 36048824 DOI: 10.1371/journal.pone.0269887 |
0.781 |
|
| 2022 |
Shiriaeva A, Park D, Kim G, Lee Y, Hou X, Jarhad DB, Kim G, Yu J, Hyun YE, Kim W, Gao ZG, Jacobson KA, Han GW, Stevens RC, Jeong LS, et al. GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches for the A Adenosine Receptor. Journal of Medicinal Chemistry. PMID 35977382 DOI: 10.1021/acs.jmedchem.2c00462 |
0.497 |
|
| 2022 |
Yue Y, Liu L, Wu LJ, Wu Y, Wang L, Li F, Liu J, Han GW, Chen B, Lin X, Brouillette RL, Breault É, Longpré JM, Shi S, Lei H, ... ... Stevens RC, et al. Structural insight into apelin receptor-G protein stoichiometry. Nature Structural & Molecular Biology. 29: 688-697. PMID 35817871 DOI: 10.1038/s41594-022-00797-5 |
0.651 |
|
| 2022 |
Li A, Zhang X, Singla J, White K, Loconte V, Hu C, Zhang C, Li S, Li W, Francis JP, Wang C, Sali A, Sun L, He X, Stevens RC. Auto-segmentation and time-dependent systematic analysis of mesoscale cellular structure in β-cells during insulin secretion. Plos One. 17: e0265567. PMID 35324950 DOI: 10.1371/journal.pone.0265567 |
0.776 |
|
| 2022 |
Singla J, Burdsall K, Cantrell B, Halsey JR, McDowell A, McGregor C, Mittal S, Stevens RC, Su S, Thomopoulos A, Vaillant T, White KL, Zhang B, Berman HM. A new visual design language for biological structures in a cell. Structure (London, England : 1993). PMID 35093200 DOI: 10.1016/j.str.2022.01.002 |
0.774 |
|
| 2021 |
Raveh B, Sun L, White KL, Sanyal T, Tempkin J, Zheng D, Bharath K, Singla J, Wang C, Zhao J, Li A, Graham NA, Kesselman C, Stevens RC, Sali A. Bayesian metamodeling of complex biological systems across varying representations. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34453000 DOI: 10.1073/pnas.2104559118 |
0.773 |
|
| 2021 |
Zhao F, Zhang C, Zhou Q, Hang K, Zou X, Chen Y, Wu F, Rao Q, Dai A, Yin W, Shen DD, Zhang Y, Xia T, Stevens RC, Xu E, et al. Structural insights into hormone recognition by the human glucose-dependent insulinotropic polypeptide receptor. Elife. 10. PMID 34254582 DOI: 10.7554/eLife.68719 |
0.333 |
|
| 2021 |
Wang Z, Gurlo T, Matveyenko AV, Elashoff D, Wang P, Rosenberger M, Junge JA, Stevens RC, White KL, Fraser SE, Butler PC. Live-cell imaging of glucose-induced metabolic coupling of β and α cell metabolism in health and type 2 diabetes. Communications Biology. 4: 594. PMID 34012065 DOI: 10.1038/s42003-021-02113-1 |
0.654 |
|
| 2021 |
Singla J, White KL, Stevens RC, Alber F. Assessment of scoring functions to rank the quality of 3D subtomogram clusters from cryo-electron tomography. Journal of Structural Biology. 107727. PMID 33753204 DOI: 10.1016/j.jsb.2021.107727 |
0.774 |
|
| 2020 |
White KL, Singla J, Loconte V, Chen JH, Ekman A, Sun L, Zhang X, Francis JP, Li A, Lin W, Tseng K, McDermott G, Alber F, Sali A, Larabell C, ... Stevens RC, et al. Visualizing subcellular rearrangements in intact β cells using soft x-ray tomography. Science Advances. 6. PMID 33298443 DOI: 10.1126/sciadv.abc8262 |
0.78 |
|
| 2020 |
Zhang X, Carter SD, Singla J, White KL, Butler PC, Stevens RC, Jensen GJ. Visualizing insulin vesicle neighborhoods in β cells by cryo-electron tomography. Science Advances. 6. PMID 33298442 DOI: 10.1126/sciadv.abc8258 |
0.768 |
|
| 2020 |
Martin C, Gimenez LE, Williams SY, Jing Y, Wu Y, Hollanders C, Van der Poorten O, Gonzalez S, Van Holsbeeck K, Previti S, Lamouroux A, Zhao S, Tourwé D, Stevens RC, Cone RD, et al. Structure-Based Design of Melanocortin 4 Receptor Ligands Based on the SHU-9119-hMC4R Cocrystal Structure†. Journal of Medicinal Chemistry. PMID 33190475 DOI: 10.1021/acs.jmedchem.0c01620 |
0.359 |
|
| 2020 |
Zambaldo C, Koh M, Nasertorabi F, Han GW, Chatterjee A, Stevens RC, Schultz PG. An orthogonal seryl-tRNA synthetase/tRNA pair for noncanonical amino acid mutagenesis in Escherichia coli. Bioorganic & Medicinal Chemistry. 28: 115662. PMID 33069069 DOI: 10.1016/J.Bmc.2020.115662 |
0.478 |
|
| 2020 |
Li JC, Nasertorabi F, Xuan W, Han GW, Stevens RC, Schultz PG. A Single Reactive Noncanonical Amino Acid is Able to Dramatically Stabilize Protein Structure. Acs Chemical Biology. PMID 33006884 DOI: 10.1021/acschembio.0c00196 |
0.409 |
|
| 2020 |
Dai Z, Zhang XN, Nasertorabi F, Cheng Q, Li J, Katz BB, Smbatyan G, Pei H, Louie SG, Lenz HJ, Stevens RC, Zhang Y. Synthesis of site-specific antibody-drug conjugates by ADP-ribosyl cyclases. Science Advances. 6: eaba6752. PMID 32537509 DOI: 10.1126/Sciadv.Aba6752 |
0.316 |
|
| 2020 |
Yu J, Gimenez LE, Hernandez CC, Wu Y, Wein AH, Han GW, McClary K, Mittal SR, Burdsall K, Stauch B, Wu L, Stevens SN, Peisley A, Williams SY, Chen V, ... ... Stevens RC, et al. Determination of the melanocortin-4 receptor structure identifies Ca as a cofactor for ligand binding. Science (New York, N.Y.). 368: 428-433. PMID 32327598 DOI: 10.1126/Science.Aaz8995 |
0.833 |
|
| 2020 |
Wu F, Yang L, Hang K, Laursen M, Wu L, Han GW, Ren Q, Roed NK, Lin G, Hanson MA, Jiang H, Wang MW, Reedtz-Runge S, Song G, Stevens RC. Full-length human GLP-1 receptor structure without orthosteric ligands. Nature Communications. 11: 1272. PMID 32152292 DOI: 10.1038/S41467-020-14934-5 |
0.645 |
|
| 2020 |
Lu Y, Qin S, Zhang B, Dai A, Cai X, Ma M, Gao ZG, Yang D, Stevens RC, Jacobson KA, Wang MW, Shui W. Correction to Accelerating the Throughput of Affinity Mass Spectrometry-Based Ligand Screening toward a G Protein-Coupled Receptor. Analytical Chemistry. PMID 32125824 DOI: 10.1021/Acs.Analchem.0C00754 |
0.504 |
|
| 2020 |
Lamichhane R, Liu JJ, White KL, Katritch V, Stevens RC, Wüthrich K, Millar DP. Biased Signaling of the G-Protein-Coupled Receptor βAR Is Governed by Conformational Exchange Kinetics. Structure (London, England : 1993). PMID 31978323 DOI: 10.1016/J.Str.2020.01.001 |
0.824 |
|
| 2019 |
Zhou Q, Yang D, Wu M, Guo Y, Guo W, Zhong L, Cai X, Dai A, Jang W, Shakhnovich EI, Liu ZJ, Stevens RC, Lambert NA, Babu MM, Wang MW, et al. Common activation mechanism of class A GPCRs. Elife. 8. PMID 31855179 DOI: 10.7554/Elife.50279 |
0.434 |
|
| 2019 |
Claff T, Yu J, Blais V, Patel N, Martin C, Wu L, Han GW, Holleran BJ, Van der Poorten O, White KL, Hanson MA, Sarret P, Gendron L, Cherezov V, Katritch V, ... ... Stevens RC, et al. Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists. Science Advances. 5: eaax9115. PMID 31807708 DOI: 10.1126/Sciadv.Aax9115 |
0.818 |
|
| 2019 |
Chen X, Xu Y, Qu L, Wu L, Han GW, Guo Y, Wu Y, Zhou Q, Sun Q, Chu C, Yang J, Yang L, Wang Q, Yuan S, Wang L, ... ... Stevens RC, et al. Molecular Mechanism for Ligand Recognition and Subtype Selectivity of α Adrenergic Receptor. Cell Reports. 29: 2936-2943.e4. PMID 31801061 DOI: 10.1016/J.Celrep.2019.10.112 |
0.434 |
|
| 2019 |
Qu L, Zhou Q, Xu Y, Guo Y, Chen X, Yao D, Han GW, Liu ZJ, Stevens RC, Zhong G, Wu D, Zhao S. Structural Basis of the Diversity of Adrenergic Receptors. Cell Reports. 29: 2929-2935.e4. PMID 31801060 DOI: 10.1016/J.Celrep.2019.10.088 |
0.482 |
|
| 2019 |
Audet M, Villers K, Velasquez J, Chu M, Hanson C, Stevens RC. Small-scale approach for precrystallization screening in GPCR X-ray crystallography. Nature Protocols. PMID 31784719 DOI: 10.1038/S41596-019-0259-Y |
0.641 |
|
| 2019 |
Laprairie RB, Vemuri K, Stahl EL, Korde A, Ho JH, Grim TW, Hua T, Wu Y, Stevens RC, Liu ZJ, Makriyannis A, Bohn LM. Probing the CB1 cannabinoid receptor binding pocket with AM6538, a high-affinity irreversible antagonist. Molecular Pharmacology. PMID 31515283 DOI: 10.1124/Mol.119.116483 |
0.39 |
|
| 2019 |
Zhou F, Ding K, Zhou Y, Liu Y, Liu X, Zhao F, Wu Y, Zhang X, Tan Q, Stevens RC, Xu F, Tan W, Xiao Y, Zhao S, Tao H. Co-Localization Strategy Unveils an Underside Binding Site in the Transmembrane Domain of Smoothened Receptor. Journal of Medicinal Chemistry. PMID 31408335 DOI: 10.1021/Acs.Jmedchem.9B00283 |
0.719 |
|
| 2019 |
Li JC, Nastertorabi F, Xuan W, Han GW, Stevens RC, Schultz PG. A Single Reactive Noncanonical Amino Acid Is Able to Dramatically Stabilize Protein Structure. Acs Chemical Biology. PMID 31181898 DOI: 10.1021/acschembio.9b00002 |
0.491 |
|
| 2019 |
Xue D, Ye L, Zheng J, Wu Y, Zhang X, Xu Y, Li T, Stevens RC, Xu F, Zhuang M, Zhao S, Zhao F, Tao H. The structure-based traceless specific fluorescence labeling of the smoothened receptor. Organic & Biomolecular Chemistry. PMID 31180094 DOI: 10.1039/C9Ob00654K |
0.718 |
|
| 2019 |
Lu Y, Qin S, Zhang B, Dai A, Cai X, Ma M, Gao ZG, Yang D, Stevens RC, Jacobson KA, Wang MW, Shui W. Accelerating the Throughput of Affinity Mass Spectrometry-Based Ligand Screening towards a G Protein-Coupled Receptor. Analytical Chemistry. PMID 31094506 DOI: 10.1021/Acs.Analchem.9B00477 |
0.517 |
|
| 2019 |
Stauch B, Johansson LC, McCorvy JD, Patel N, Han GW, Huang XP, Gati C, Batyuk A, Slocum ST, Ishchenko A, Brehm W, White TA, Michaelian N, Madsen C, Zhu L, ... ... Stevens RC, et al. Publisher Correction: Structural basis of ligand recognition at the human MT melatonin receptor. Nature. PMID 31048811 DOI: 10.1038/S41586-019-1209-0 |
0.725 |
|
| 2019 |
Gutierrez MG, Deyell J, White KL, Dalle Ore LC, Cherezov V, Stevens RC, Malmstadt N. The lipid phase preference of the adenosine A receptor depends on its ligand binding state. Chemical Communications (Cambridge, England). PMID 31038495 DOI: 10.1039/C8Cc10130B |
0.581 |
|
| 2019 |
Stauch B, Johansson LC, McCorvy JD, Patel N, Han GW, Huang XP, Gati C, Batyuk A, Slocum ST, Ishchenko A, Brehm W, White TA, Michaelian N, Madsen C, Zhu L, ... ... Stevens RC, et al. Structural basis of ligand recognition at the human MT melatonin receptor. Nature. PMID 31019306 DOI: 10.1038/S41586-019-1141-3 |
0.768 |
|
| 2019 |
Johansson LC, Stauch B, McCorvy JD, Han GW, Patel N, Huang XP, Batyuk A, Gati C, Slocum ST, Li C, Grandner JM, Hao S, Olsen RHJ, Tribo AR, Zaare S, ... ... Stevens RC, et al. XFEL structures of the human MT melatonin receptor reveal the basis of subtype selectivity. Nature. PMID 31019305 DOI: 10.1038/s41586-019-1144-0 |
0.784 |
|
| 2019 |
Zhao S, Wu B, Stevens RC. Advancing Chemokine GPCR Structure Based Drug Discovery. Structure (London, England : 1993). 27: 405-408. PMID 30840872 DOI: 10.1016/J.Str.2019.02.004 |
0.572 |
|
| 2019 |
Xu M, Singla J, Tocheva EI, Chang YW, Stevens RC, Jensen GJ, Alber F. De Novo Structural Pattern Mining in Cellular Electron Cryotomograms. Structure (London, England : 1993). PMID 30744995 DOI: 10.1016/J.Str.2019.01.005 |
0.766 |
|
| 2019 |
Chen S, Lu M, Liu D, Yang L, Yi C, Ma L, Zhang H, Liu Q, Frimurer TM, Wang MW, Schwartz TW, Stevens RC, Wu B, Wüthrich K, Zhao Q. Human substance P receptor binding mode of the antagonist drug aprepitant by NMR and crystallography. Nature Communications. 10: 638. PMID 30733446 DOI: 10.1038/S41467-019-08568-5 |
0.718 |
|
| 2019 |
Munk C, Mutt E, Isberg V, Nikolajsen LF, Bibbe JM, Flock T, Hanson MA, Stevens RC, Deupi X, Gloriam DE. An online resource for GPCR structure determination and analysis. Nature Methods. PMID 30664776 DOI: 10.1038/S41592-018-0302-X |
0.644 |
|
| 2019 |
WHITE KL, SINGLA J, STEVENS RC. 335-LB: Towards Generating Spatiotemporal Multiscale Models of Pancreatic ß Cells Diabetes. 68: 335-LB. DOI: 10.2337/Db19-335-Lb |
0.78 |
|
| 2019 |
White KL, Singla J, Francis J, Chen J, Ekman A, Larabell C, Stevens RC. Mesoscale Architecture of Beta Cells Upon Glucose and Ex-4 Stimulation Biophysical Journal. 116: 431a. DOI: 10.1016/J.Bpj.2018.11.2322 |
0.756 |
|
| 2018 |
Li X, Hua T, Vemuri K, Ho JH, Wu Y, Wu L, Popov P, Benchama O, Zvonok N, Locke K, Qu L, Han GW, Iyer MR, Cinar R, Coffey NJ, ... ... Stevens RC, et al. Crystal Structure of the Human Cannabinoid Receptor CB2. Cell. PMID 30639103 DOI: 10.1016/j.cell.2018.12.011 |
0.645 |
|
| 2018 |
Audet M, White KL, Breton B, Zarzycka B, Han GW, Lu Y, Gati C, Batyuk A, Popov P, Velasquez J, Manahan D, Hu H, Weierstall U, Liu W, Shui W, ... ... Stevens RC, et al. Publisher Correction: Crystal structure of misoprostol bound to the labor inducer prostaglandin E receptor. Nature Chemical Biology. PMID 30573766 DOI: 10.1038/S41589-018-0214-1 |
0.785 |
|
| 2018 |
Audet M, White KL, Breton B, Zarzycka B, Han GW, Lu Y, Gati C, Batyuk A, Popov P, Velasquez J, Manahan D, Hu H, Weierstall U, Liu W, Shui W, ... ... Stevens RC, et al. Crystal structure of misoprostol bound to the labor inducer prostaglandin E receptor. Nature Chemical Biology. PMID 30510194 DOI: 10.1038/S41589-018-0160-Y |
0.831 |
|
| 2018 |
Sušac L, Eddy MT, Didenko T, Stevens RC, Wüthrich K. A adenosine receptor functional states characterized by F-NMR. Proceedings of the National Academy of Sciences of the United States of America. PMID 30463958 DOI: 10.1073/Pnas.1813649115 |
0.771 |
|
| 2018 |
Audet M, Stevens RC. Emerging Structural Biology of Lipid G-Protein Coupled Receptors. Protein Science : a Publication of the Protein Society. PMID 30239054 DOI: 10.1002/Pro.3509 |
0.705 |
|
| 2018 |
Yang S, Wu Y, Xu TH, de Waal PW, He Y, Pu M, Chen Y, DeBruine ZJ, Zhang B, Zaidi SA, Popov P, Guo Y, Han GW, Lu Y, Suino-Powell K, ... ... Stevens RC, et al. Crystal structure of the Frizzled 4 receptor in a ligand-free state. Nature. PMID 30135577 DOI: 10.1038/S41586-018-0447-X |
0.731 |
|
| 2018 |
Liu X, Gao ZG, Wu Y, Stevens RC, Jacobson KA, Zhao S. Author Correction: Salvianolic acids from antithrombotic Traditional Chinese Medicine Danshen are antagonists of human P2Y and P2Y receptors. Scientific Reports. 8: 11380. PMID 30038283 DOI: 10.1038/S41598-018-29406-6 |
0.44 |
|
| 2018 |
Popov P, Peng Y, Shen L, Stevens RC, Cherezov V, Liu ZJ, Katritch V. Computational design of thermostabilizing point mutations for G protein-coupled receptors. Elife. 7. PMID 29927385 DOI: 10.7554/Elife.34729 |
0.64 |
|
| 2018 |
Eddy MT, Gao ZG, Mannes P, Patel N, Jacobson KA, Katritch V, Stevens RC, Wüthrich K. Extrinsic Tryptophans as NMR Probes of Allosteric Coupling in Membrane Proteins: Application to the A2A Adenosine Receptor. Journal of the American Chemical Society. PMID 29874058 DOI: 10.1021/Jacs.8B03805 |
0.816 |
|
| 2018 |
Cao C, Tan Q, Xu C, He L, Yang L, Zhou Y, Zhou Y, Qiao A, Lu M, Yi C, Han GW, Wang X, Li X, Yang H, Rao Z, ... ... Stevens RC, et al. Structural basis for signal recognition and transduction by platelet-activating-factor receptor. Nature Structural & Molecular Biology. PMID 29808000 DOI: 10.1038/S41594-018-0068-Y |
0.657 |
|
| 2018 |
Liu X, Gao ZG, Wu Y, Stevens RC, Jacobson KA, Zhao S. Salvianolic acids from antithrombotic Traditional Chinese Medicine Danshen are antagonists of human P2Y and P2Y receptors. Scientific Reports. 8: 8084. PMID 29795391 DOI: 10.1038/S41598-018-26577-0 |
0.513 |
|
| 2018 |
Qin S, Meng M, Yang D, Bai W, Lu Y, Peng Y, Song G, Wu Y, Zhou Q, Zhao S, Huang X, McCorvy JD, Cai X, Dai A, Roth BL, ... ... Stevens RC, et al. High-throughput identification of G protein-coupled receptor modulators through affinity mass spectrometry screening. Chemical Science. 9: 3192-3199. PMID 29732102 DOI: 10.1039/C7Sc04698G |
0.604 |
|
| 2018 |
Yang Z, Han S, Keller M, Kaiser A, Bender BJ, Bosse M, Burkert K, Kögler LM, Wifling D, Bernhardt G, Plank N, Littmann T, Schmidt P, Yi C, Li B, ... ... Stevens RC, et al. Structural basis of ligand binding modes at the neuropeptide Y Y receptor. Nature. PMID 29670288 DOI: 10.1038/S41586-018-0046-X |
0.654 |
|
| 2018 |
Peng Y, Zhao S, Wu Y, Cao H, Xu Y, Liu X, Shui W, Cheng J, Zhao S, Shen L, Ma J, Quinn RJ, Stevens RC, Zhong G, Liu ZJ. Identification of natural products as novel ligands for the human 5-HTreceptor. Biophysics Reports. 4: 50-61. PMID 29577069 DOI: 10.1007/S41048-018-0047-1 |
0.454 |
|
| 2018 |
Vass M, Kooistra AJ, Yang D, Stevens RC, Wang MW, de Graaf C. Chemical Diversity in the G Protein-Coupled Receptor Superfamily. Trends in Pharmacological Sciences. PMID 29576399 DOI: 10.1016/J.Tips.2018.02.004 |
0.469 |
|
| 2018 |
Singla J, McClary KM, White KL, Alber F, Sali A, Stevens RC. Opportunities and Challenges in Building a Spatiotemporal Multi-scale Model of the Human Pancreatic β Cell. Cell. 173: 11-19. PMID 29570991 DOI: 10.1016/J.Cell.2018.03.014 |
0.77 |
|
| 2018 |
Peng Y, McCorvy JD, Harpsøe K, Lansu K, Yuan S, Popov P, Qu L, Pu M, Che T, Nikolajsen LF, Huang XP, Wu Y, Shen L, Bjørn-Yoshimoto WE, Ding K, ... ... Stevens RC, et al. 5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology. Cell. PMID 29398112 DOI: 10.1016/J.Cell.2018.01.001 |
0.828 |
|
| 2018 |
White KL, Eddy MT, Gao ZG, Han GW, Lian T, Deary A, Patel N, Jacobson KA, Katritch V, Stevens RC. Structural Connection between Activation Microswitch and Allosteric Sodium Site in GPCR Signaling. Structure (London, England : 1993). PMID 29395784 DOI: 10.1016/J.Str.2017.12.013 |
0.831 |
|
| 2018 |
Che T, Majumdar S, Zaidi SA, Ondachi P, McCorvy JD, Wang S, Mosier PD, Uprety R, Vardy E, Krumm BE, Han GW, Lee MY, Pardon E, Steyaert J, Huang XP, ... ... Stevens RC, et al. Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor. Cell. PMID 29307491 DOI: 10.1016/J.Cell.2017.12.011 |
0.813 |
|
| 2018 |
Zhang H, Qiao A, Yang L, Van Eps N, Frederiksen KS, Yang D, Dai A, Cai X, Zhang H, Yi C, Cao C, He L, Yang H, Lau J, Ernst OP, ... ... Stevens RC, et al. Structure of the glucagon receptor in complex with a glucagon analogue. Nature. 553: 106-110. PMID 29300013 DOI: 10.1038/Nature25153 |
0.721 |
|
| 2018 |
Popov P, Peng Y, Shen L, Stevens RC, Cherezov V, Liu Z, Katritch V. Author response: Computational design of thermostabilizing point mutations for G protein-coupled receptors Elife. DOI: 10.7554/Elife.34729.019 |
0.598 |
|
| 2018 |
WHITE KL, MCCLARY K, SINGLA J, STEVENS RC. Towards Generating Spatiotemporal Multiscale Models of Human Pancreatic Beta Cells Diabetes. 67: 2171-P. DOI: 10.2337/Db18-2171-P |
0.781 |
|
| 2018 |
Audet M, White KL, Breton B, Zarzycka B, Han GW, Lu Y, Gati C, Batyuk A, Popov P, Velasquez J, Manahan D, Hu H, Weierstall U, Liu W, Shui W, ... ... Stevens RC, et al. Crystal structure of EP3 receptor bound to misoprostol-FA Nature Chemical Biology. DOI: 10.2210/Pdb6M9T/Pdb |
0.768 |
|
| 2017 |
Ye L, Ding K, Zhao F, Liu X, Wu Y, Liu Y, Xue D, Zhou F, Zhang X, Stevens RC, Xu F, Zhao S, Tao H. A structurally guided dissection-then-evolution strategy for ligand optimization of smoothened receptor. Medchemcomm. 8: 1332-1336. PMID 30108845 DOI: 10.1039/C7Md00104E |
0.751 |
|
| 2017 |
Roach JJ, Sasano Y, Schmid CL, Zaidi S, Katritch V, Stevens RC, Bohn LM, Shenvi RA. Dynamic Strategic Bond Analysis Yields a Ten-Step Synthesis of 20-nor-Salvinorin A, a Potent κ-OR Agonist. Acs Central Science. 3: 1329-1336. PMID 29296674 DOI: 10.1021/Acscentsci.7B00488 |
0.633 |
|
| 2017 |
Eddy MT, Lee MY, Gao ZG, White KL, Didenko T, Horst R, Audet M, Stanczak P, McClary KM, Han GW, Jacobson KA, Stevens RC, Wüthrich K. Allosteric Coupling of Drug Binding and Intracellular Signaling in the A2A Adenosine Receptor. Cell. PMID 29290469 DOI: 10.1016/J.Cell.2017.12.004 |
0.814 |
|
| 2017 |
de Graaf C, Song G, Cao C, Zhao Q, Wang MW, Wu B, Stevens RC. Extending the Structural View of Class B GPCRs. Trends in Biochemical Sciences. PMID 29132948 DOI: 10.1016/J.Tibs.2017.10.003 |
0.65 |
|
| 2017 |
Zhou XE, He Y, de Waal PW, Gao X, Kang Y, Van Eps N, Yin Y, Pal K, Goswami D, White TA, Barty A, Latorraca NR, Chapman HN, Hubbell WL, Dror RO, ... Stevens RC, et al. Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors. Cell. 170: 457-469.e13. PMID 28753425 DOI: 10.1016/J.Cell.2017.07.002 |
0.417 |
|
| 2017 |
Wacker D, Stevens RC, Roth BL. How Ligands Illuminate GPCR Molecular Pharmacology. Cell. 170: 414-427. PMID 28753422 DOI: 10.1016/J.Cell.2017.07.009 |
0.761 |
|
| 2017 |
Ishchenko A, Wacker D, Kapoor M, Zhang A, Han GW, Basu S, Patel N, Messerschmidt M, Weierstall U, Liu W, Katritch V, Roth BL, Stevens RC, Cherezov V. Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody. Proceedings of the National Academy of Sciences of the United States of America. PMID 28716900 DOI: 10.1073/Pnas.1700891114 |
0.828 |
|
| 2017 |
Wu F, Song G, de Graaf C, Stevens RC. Structure and function of peptide-binding G protein-coupled receptors. Journal of Molecular Biology. PMID 28705763 DOI: 10.1016/J.Jmb.2017.06.022 |
0.417 |
|
| 2017 |
Hua T, Vemuri K, Nikas SP, Laprairie RB, Wu Y, Qu L, Pu M, Korde A, Jiang S, Ho JH, Han GW, Ding K, Li X, Liu H, Hanson MA, ... ... Stevens RC, et al. Crystal structures of agonist-bound human cannabinoid receptor CB1. Nature. PMID 28678776 DOI: 10.1038/Nature23272 |
0.682 |
|
| 2017 |
Zheng Y, Han GW, Abagyan R, Wu B, Stevens RC, Cherezov V, Kufareva I, Handel TM. Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist Reveals Mechanisms of Chemokine Recognition and Molecular Mimicry by HIV. Immunity. 46: 1005-1017.e5. PMID 28636951 DOI: 10.1016/J.Immuni.2017.05.002 |
0.513 |
|
| 2017 |
Ma Y, Yue Y, Ma Y, Zhang Q, Zhou Q, Song Y, Shen Y, Li X, Ma X, Li C, Hanson MA, Han GW, Sickmier EA, Swaminath G, Zhao S, ... Stevens RC, et al. Structural Basis for Apelin Control of the Human Apelin Receptor. Structure (London, England : 1993). PMID 28528775 DOI: 10.1016/J.Str.2017.04.008 |
0.68 |
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| 2017 |
Zhang H, Qiao A, Yang D, Yang L, Dai A, de Graaf C, Reedtz-Runge S, Dharmarajan V, Zhang H, Han GW, Grant TD, Sierra RG, Weierstall U, Nelson G, Liu W, ... ... Stevens RC, et al. Structure of the full-length glucagon class B G-protein-coupled receptor. Nature. PMID 28514451 DOI: 10.1038/Nature22363 |
0.752 |
|
| 2017 |
Song G, Yang D, Wang Y, de Graaf C, Zhou Q, Jiang S, Liu K, Cai X, Dai A, Lin G, Liu D, Wu F, Wu Y, Zhao S, Ye L, ... ... Stevens RC, et al. Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators. Nature. PMID 28514449 DOI: 10.1038/Nature22378 |
0.706 |
|
| 2017 |
Zhang X, Zhao F, Wu Y, Yang J, Han GW, Zhao S, Ishchenko A, Ye L, Lin X, Ding K, Dharmarajan V, Griffin PR, Gati C, Nelson G, Hunter MS, ... ... Stevens RC, et al. Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand. Nature Communications. 8: 15383. PMID 28513578 DOI: 10.1038/Ncomms15383 |
0.799 |
|
| 2017 |
Koh M, Nasertorabi F, Han GW, Stevens RC, Schultz PG. Generation of an Orthogonal Protein-Protein Interface with a Noncanonical Amino Acid. Journal of the American Chemical Society. PMID 28413876 DOI: 10.1021/Jacs.7B02273 |
0.497 |
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| 2017 |
Zhang H, Han GW, Batyuk A, Ishchenko A, White KL, Patel N, Sadybekov A, Zamlynny B, Rudd MT, Hollenstein K, Tolstikova A, White TA, Hunter MS, Weierstall U, Liu W, ... ... Stevens RC, et al. Structural basis for selectivity and diversity in angiotensin II receptors. Nature. PMID 28379944 DOI: 10.1038/Nature22035 |
0.825 |
|
| 2017 |
Zheng Z, Huang XP, Mangano TJ, Zou R, Chen X, Zaidi S, Roth BL, Stevens RC, Katritch V. Structure based discovery of new antagonist and biased agonist chemotypes for the Kappa Opioid Receptor. Journal of Medicinal Chemistry. PMID 28339199 DOI: 10.1021/Acs.Jmedchem.7B00109 |
0.643 |
|
| 2017 |
Zheng Y, Qin L, Han GW, Gustavsson M, Kawamura T, Abagyan R, Stevens RC, Cherezov, Kufareva I, Handel TM. Crystal Structure of CC Chemokine Receptor 5 (CCR5) in complex with high potency HIV entry inhibitor 5P7-CCL5 Immunity. DOI: 10.2210/Pdb5Uiw/Pdb |
0.365 |
|
| 2016 |
Zheng Y, Qin L, Zacarías NV, de Vries H, Han GW, Gustavsson M, Dabros M, Zhao C, Cherney RJ, Carter P, Stamos D, Abagyan R, Cherezov V, Stevens RC, IJzerman AP, et al. Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists. Nature. PMID 27926736 DOI: 10.1038/Nature20605 |
0.465 |
|
| 2016 |
Eddy MT, Didenko T, Stevens RC, Wüthrich K. β2-Adrenergic Receptor Conformational Response to Fusion Protein in the Third Intracellular Loop. Structure (London, England : 1993). 24: 2190-2197. PMID 27839952 DOI: 10.1016/J.Str.2016.09.015 |
0.783 |
|
| 2016 |
Hua T, Vemuri K, Pu M, Qu L, Han GW, Wu Y, Zhao S, Shui W, Li S, Korde A, Laprairie RB, Stahl EL, Ho JH, Zvonok N, Zhou H, ... ... Stevens RC, et al. Crystal Structure of the Human Cannabinoid Receptor CB1. Cell. 167: 750-762.e14. PMID 27768894 DOI: 10.1016/J.Cell.2016.10.004 |
0.746 |
|
| 2016 |
Batyuk A, Galli L, Ishchenko A, Han GW, Gati C, Popov PA, Lee MY, Stauch B, White TA, Barty A, Aquila A, Hunter MS, Liang M, Boutet S, Pu M, ... ... Stevens RC, et al. Native phasing of x-ray free-electron laser data for a G protein-coupled receptor. Science Advances. 2: e1600292. PMID 27679816 DOI: 10.1126/Sciadv.1600292 |
0.654 |
|
| 2016 |
Yuan S, Chan HC, Vogel H, Filipek S, Stevens RC, Palczewski K. The Molecular Mechanism of P2Y1 Receptor Activation. Angewandte Chemie (International Ed. in English). PMID 27460867 DOI: 10.1002/Anie.201605147 |
0.455 |
|
| 2016 |
Lv X, Liu J, Shi Q, Tan Q, Wu D, Skinner JJ, Walker AL, Zhao L, Gu X, Chen N, Xue L, Si P, Zhang L, Wang Z, Katritch V, ... ... Stevens RC, et al. In vitro expression and analysis of the 826 human G protein-coupled receptors. Protein & Cell. PMID 27085723 DOI: 10.1007/S13238-016-0263-8 |
0.643 |
|
| 2016 |
Zhou XE, Gao X, Barty A, Kang Y, He Y, Liu W, Ishchenko A, White TA, Yefanov O, Han GW, Xu Q, de Waal PW, Suino-Powell KM, Boutet S, Williams GJ, ... ... Stevens RC, et al. X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex. Scientific Data. 3: 160021. PMID 27070998 DOI: 10.1038/Sdata.2016.21 |
0.467 |
|
| 2016 |
Yang D, de Graaf C, Yang L, Song G, Dai A, Cai X, Feng Y, Reedtz-Runge S, Hanson MA, Yang H, Jiang H, Stevens RC, Wang MW. Structural Determinants of Binding the Seven-transmembrane Domain of the Glucagon-like Peptide-1 Receptor. The Journal of Biological Chemistry. PMID 27059958 DOI: 10.1074/Jbc.M116.721977 |
0.605 |
|
| 2016 |
Lee M, Patel N, Katritch V, Stevens RC, Cherezov V. Structural Studies of the Human Kappa Opioid Receptor Active State Conformations Biophysical Journal. 110: 38a-39a. DOI: 10.1016/J.Bpj.2015.11.275 |
0.768 |
|
| 2016 |
White KL, Lian T, Stevens RC. Biochemical Characterization and Structure Determination of the Class C TAS1R Subfamily of Chemosensory Receptors Biophysical Journal. 110: 395a. DOI: 10.1016/J.Bpj.2015.11.2135 |
0.652 |
|
| 2015 |
Lamichhane R, Liu JJ, Pljevaljcic G, White KL, van der Schans E, Katritch V, Stevens RC, Wüthrich K, Millar DP. Single-molecule view of basal activity and activation mechanisms of the G protein-coupled receptor β2AR. Proceedings of the National Academy of Sciences of the United States of America. 112: 14254-9. PMID 26578769 DOI: 10.1073/Pnas.1519626112 |
0.829 |
|
| 2015 |
Sušac L, O'Connor C, Stevens RC, Wüthrich K. In-Membrane Chemical Modification (IMCM) for Site-Specific Chromophore Labeling of GPCRs. Angewandte Chemie (International Ed. in English). 54: 15246-9. PMID 26545333 DOI: 10.1002/Anie.201508506 |
0.542 |
|
| 2015 |
Miller RL, Thompson AA, Trapella C, Guerrini R, Malfacini D, Patel N, Han GW, Cherezov V, Caló G, Katritch V, Stevens RC. The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor. Structure (London, England : 1993). PMID 26526853 DOI: 10.1016/J.Str.2015.07.024 |
0.819 |
|
| 2015 |
Zhang H, Unal H, Desnoyer R, Han GW, Patel N, Katritch V, Karnik SS, Cherezov V, Stevens RC. Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor. The Journal of Biological Chemistry. PMID 26420482 DOI: 10.1074/Jbc.M115.689000 |
0.76 |
|
| 2015 |
O'Connor C, White KL, Doncescu N, Didenko T, Roth BL, Czaplicki G, Stevens RC, Wüthrich K, Milon A. NMR structure and dynamics of the agonist dynorphin peptide bound to the human kappa opioid receptor. Proceedings of the National Academy of Sciences of the United States of America. 112: 11852-7. PMID 26372966 DOI: 10.1073/Pnas.1510117112 |
0.686 |
|
| 2015 |
Kiselev E, Balasubramanian R, Uliassi E, Brown KA, Trujillo K, Katritch V, Hammes E, Stevens RC, Harden TK, Jacobson KA. Design, synthesis, pharmacological characterization of a fluorescent agonist of the P2Y14 receptor. Bioorganic & Medicinal Chemistry Letters. 25: 4733-9. PMID 26303895 DOI: 10.1016/J.Bmcl.2015.08.021 |
0.699 |
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| 2015 |
Yang L, Yang D, de Graaf C, Moeller A, West GM, Dharmarajan V, Wang C, Siu FY, Song G, Reedtz-Runge S, Pascal BD, Wu B, Potter CS, Zhou H, Griffin PR, ... ... Stevens RC, et al. Conformational states of the full-length glucagon receptor. Nature Communications. 6: 7859. PMID 26227798 DOI: 10.1038/Ncomms8859 |
0.827 |
|
| 2015 |
Kang Y, Zhou XE, Gao X, He Y, Liu W, Ishchenko A, Barty A, White TA, Yefanov O, Han GW, Xu Q, de Waal PW, Ke J, Tan MH, Zhang C, ... ... Stevens RC, et al. Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser. Nature. PMID 26200343 DOI: 10.1038/Nature14656 |
0.685 |
|
| 2015 |
Paoletta S, Sabbadin D, von Kügelgen I, Hinz S, Katritch V, Hoffmann K, Abdelrahman A, Straßburger J, Baqi Y, Zhao Q, Stevens RC, Moro S, Müller CE, Jacobson KA. Modeling ligand recognition at the P2Y12 receptor in light of X-ray structural information. Journal of Computer-Aided Molecular Design. PMID 26194851 DOI: 10.1007/S10822-015-9858-Z |
0.767 |
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| 2015 |
Vardy E, Sassano MF, Rennekamp AJ, Kroeze WK, Mosier PD, Westkaemper RB, Stevens CW, Katritch V, Stevens RC, Peterson RT, Roth BL. Single Amino Acid Variation Underlies Species-Specific Sensitivity to Amphibian Skin-Derived Opioid-like Peptides. Chemistry & Biology. 22: 764-75. PMID 26091169 DOI: 10.1016/J.Chembiol.2015.05.012 |
0.579 |
|
| 2015 |
Chrencik JE, Roth CB, Terakado M, Kurata H, Omi R, Kihara Y, Warshaviak D, Nakade S, Asmar-Rovira G, Mileni M, Mizuno H, Griffith MT, Rodgers C, Han GW, Velasquez J, ... ... Stevens RC, et al. Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1. Cell. 161: 1633-43. PMID 26091040 DOI: 10.1016/J.Cell.2015.06.002 |
0.847 |
|
| 2015 |
Xiao H, Nasertorabi F, Choi SH, Han GW, Reed SA, Stevens RC, Schultz PG. Exploring the potential impact of an expanded genetic code on protein function. Proceedings of the National Academy of Sciences of the United States of America. 112: 6961-6. PMID 26038548 DOI: 10.1073/Pnas.1507741112 |
0.502 |
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| 2015 |
Zhang H, Unal H, Gati C, Han GW, Liu W, Zatsepin NA, James D, Wang D, Nelson G, Weierstall U, Sawaya MR, Xu Q, Messerschmidt M, Williams GJ, Boutet S, ... ... Stevens RC, et al. Structure of the Angiotensin receptor revealed by serial femtosecond crystallography. Cell. 161: 833-44. PMID 25913193 DOI: 10.1016/J.Cell.2015.04.011 |
0.704 |
|
| 2015 |
Jacobson KA, Paoletta S, Katritch V, Wu B, Gao ZG, Zhao Q, Stevens RC, Kiselev E. Nucleotides Acting at P2Y Receptors: Connecting Structure and Function. Molecular Pharmacology. 88: 220-30. PMID 25837834 DOI: 10.1124/Mol.114.095711 |
0.798 |
|
| 2015 |
Zhang D, Gao ZG, Zhang K, Kiselev E, Crane S, Wang J, Paoletta S, Yi C, Ma L, Zhang W, Han GW, Liu H, Cherezov V, Katritch V, Jiang H, ... Stevens RC, et al. Two disparate ligand-binding sites in the human P2Y1 receptor. Nature. 520: 317-21. PMID 25822790 DOI: 10.1038/Nature14287 |
0.791 |
|
| 2015 |
Pearson AD, Mills JH, Song Y, Nasertorabi F, Han GW, Baker D, Stevens RC, Schultz PG. Transition states. Trapping a transition state in a computationally designed protein bottle. Science (New York, N.Y.). 347: 863-7. PMID 25700516 DOI: 10.1126/Science.Aaa2424 |
0.483 |
|
| 2015 |
Fenalti G, Zatsepin NA, Betti C, Giguere P, Han GW, Ishchenko A, Liu W, Guillemyn K, Zhang H, James D, Wang D, Weierstall U, Spence JC, Boutet S, Messerschmidt M, ... ... Stevens RC, et al. Structural basis for bifunctional peptide recognition at human δ-opioid receptor. Nature Structural & Molecular Biology. 22: 265-8. PMID 25686086 DOI: 10.1038/Nsmb.2965 |
0.632 |
|
| 2015 |
Qin L, Kufareva I, Holden LG, Wang C, Zheng Y, Zhao C, Fenalti G, Wu H, Han GW, Cherezov V, Abagyan R, Stevens RC, Handel TM. Structural biology. Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine. Science (New York, N.Y.). 347: 1117-22. PMID 25612609 DOI: 10.1126/Science.1261064 |
0.778 |
|
| 2015 |
Zhang X, Stevens RC, Xu F. The importance of ligands for G protein-coupled receptor stability. Trends in Biochemical Sciences. 40: 79-87. PMID 25601764 DOI: 10.1016/J.Tibs.2014.12.005 |
0.756 |
|
| 2015 |
Isberg V, de Graaf C, Bortolato A, Cherezov V, Katritch V, Marshall FH, Mordalski S, Pin JP, Stevens RC, Vriend G, Gloriam DE. Generic GPCR residue numbers - aligning topology maps while minding the gaps. Trends in Pharmacological Sciences. 36: 22-31. PMID 25541108 DOI: 10.1016/J.Tips.2014.11.001 |
0.655 |
|
| 2015 |
Massink A, Gutiérrez-de-Terán H, Lenselink EB, Ortiz ZacarÃas NV, Xia L, Heitman LH, Katritch V, Stevens RC, IJzerman AP. Sodium ion binding pocket mutations and adenosine A2A receptor function. Molecular Pharmacology. 87: 305-13. PMID 25473121 DOI: 10.1124/Mol.114.095737 |
0.641 |
|
| 2015 |
Lamichhane R, Liu JJ, Stevens RC, Millar DP. Conformational Dynamics of a G Protein-Coupled Receptor at the Single-Molecule Level Biophysical Journal. 108: 350a. DOI: 10.1016/J.Bpj.2014.11.1917 |
0.708 |
|
| 2014 |
Kiselev E, Barrett MO, Katritch V, Paoletta S, Weitzer CD, Brown KA, Hammes E, Yin AL, Zhao Q, Stevens RC, Harden TK, Jacobson KA. Exploring a 2-naphthoic acid template for the structure-based design of P2Y14 receptor antagonist molecular probes. Acs Chemical Biology. 9: 2833-42. PMID 25299434 DOI: 10.1021/Cb500614P |
0.744 |
|
| 2014 |
Goren MA, Morizumi T, Menon I, Joseph JS, Dittman JS, Cherezov V, Stevens RC, Ernst OP, Menon AK. Constitutive phospholipid scramblase activity of a G protein-coupled receptor. Nature Communications. 5: 5115. PMID 25296113 DOI: 10.1038/Ncomms6115 |
0.386 |
|
| 2014 |
Kufareva I, Katritch V, Stevens RC, Abagyan R. Advances in GPCR modeling evaluated by the GPCR Dock 2013 assessment: meeting new challenges. Structure (London, England : 1993). 22: 1120-39. PMID 25066135 DOI: 10.1016/J.Str.2014.06.012 |
0.649 |
|
| 2014 |
Wang C, Wu H, Evron T, Vardy E, Han GW, Huang XP, Hufeisen SJ, Mangano TJ, Urban DJ, Katritch V, Cherezov V, Caron MG, Roth BL, Stevens RC. Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs. Nature Communications. 5: 4355. PMID 25008467 DOI: 10.1038/Ncomms5355 |
0.824 |
|
| 2014 |
Zhang J, Zhang K, Gao ZG, Paoletta S, Zhang D, Han GW, Li T, Ma L, Zhang W, Müller CE, Yang H, Jiang H, Cherezov V, Katritch V, Jacobson KA, ... Stevens RC, et al. Agonist-bound structure of the human P2Y12 receptor. Nature. 509: 119-22. PMID 24784220 DOI: 10.1038/Nature13288 |
0.796 |
|
| 2014 |
Katritch V, Fenalti G, Abola EE, Roth BL, Cherezov V, Stevens RC. Allosteric sodium in class A GPCR signaling. Trends in Biochemical Sciences. 39: 233-44. PMID 24767681 DOI: 10.1016/J.Tibs.2014.03.002 |
0.67 |
|
| 2014 |
Zhang K, Zhang J, Gao ZG, Zhang D, Zhu L, Han GW, Moss SM, Paoletta S, Kiselev E, Lu W, Fenalti G, Zhang W, Müller CE, Yang H, Jiang H, ... ... Stevens RC, et al. Structure of the human P2Y12 receptor in complex with an antithrombotic drug. Nature. 509: 115-8. PMID 24670650 DOI: 10.1038/Nature13083 |
0.796 |
|
| 2014 |
Wu H, Wang C, Gregory KJ, Han GW, Cho HP, Xia Y, Niswender CM, Katritch V, Meiler J, Cherezov V, Conn PJ, Stevens RC. Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator. Science (New York, N.Y.). 344: 58-64. PMID 24603153 DOI: 10.1126/Science.1249489 |
0.808 |
|
| 2014 |
Weierstall U, James D, Wang C, White TA, Wang D, Liu W, Spence JC, Bruce Doak R, Nelson G, Fromme P, Fromme R, Grotjohann I, Kupitz C, Zatsepin NA, Liu H, ... ... Stevens RC, et al. Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography. Nature Communications. 5: 3309. PMID 24525480 DOI: 10.1038/Ncomms4309 |
0.811 |
|
| 2014 |
Fenalti G, Giguere PM, Katritch V, Huang XP, Thompson AA, Cherezov V, Roth BL, Stevens RC. Molecular control of δ-opioid receptor signalling. Nature. 506: 191-6. PMID 24413399 DOI: 10.1038/Nature12944 |
0.636 |
|
| 2014 |
Hollenstein K, de Graaf C, Bortolato A, Wang MW, Marshall FH, Stevens RC. Insights into the structure of class B GPCRs. Trends in Pharmacological Sciences. 35: 12-22. PMID 24359917 DOI: 10.1016/J.Tips.2013.11.001 |
0.426 |
|
| 2014 |
Skjevik AA, Mileni M, Baumann A, Halskau O, Teigen K, Stevens RC, Martinez A. The N-terminal sequence of tyrosine hydroxylase is a conformationally versatile motif that binds 14-3-3 proteins and membranes. Journal of Molecular Biology. 426: 150-68. PMID 24055376 DOI: 10.1016/J.Jmb.2013.09.012 |
0.782 |
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| 2013 |
Liu W, Wacker D, Gati C, Han GW, James D, Wang D, Nelson G, Weierstall U, Katritch V, Barty A, Zatsepin NA, Li D, Messerschmidt M, Boutet S, Williams GJ, ... ... Stevens RC, et al. Serial femtosecond crystallography of G protein-coupled receptors. Science (New York, N.Y.). 342: 1521-4. PMID 24357322 DOI: 10.1126/Science.1244142 |
0.825 |
|
| 2013 |
Coin I, Katritch V, Sun T, Xiang Z, Siu FY, Beyermann M, Stevens RC, Wang L. Genetically encoded chemical probes in cells reveal the binding path of urocortin-I to CRF class B GPCR. Cell. 155: 1258-69. PMID 24290358 DOI: 10.1016/J.Cell.2013.11.008 |
0.838 |
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| 2013 |
Gutiérrez-de-Terán H, Massink A, RodrÃguez D, Liu W, Han GW, Joseph JS, Katritch I, Heitman LH, Xia L, Ijzerman AP, Cherezov V, Katritch V, Stevens RC. The role of a sodium ion binding site in the allosteric modulation of the A(2A) adenosine G protein-coupled receptor. Structure (London, England : 1993). 21: 2175-85. PMID 24210756 DOI: 10.1016/J.Str.2013.09.020 |
0.66 |
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| 2013 |
Vardy E, Mosier PD, Frankowski KJ, Wu H, Katritch V, Westkaemper RB, Aubé J, Stevens RC, Roth BL. Chemotype-selective modes of action of κ-opioid receptor agonists. The Journal of Biological Chemistry. 288: 34470-83. PMID 24121503 DOI: 10.1074/Jbc.M113.515668 |
0.806 |
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| 2013 |
Tan Q, Zhu Y, Li J, Chen Z, Han GW, Kufareva I, Li T, Ma L, Fenalti G, Li J, Zhang W, Xie X, Yang H, Jiang H, Cherezov V, ... ... Stevens RC, et al. Structure of the CCR5 chemokine receptor-HIV entry inhibitor maraviroc complex. Science (New York, N.Y.). 341: 1387-90. PMID 24030490 DOI: 10.1126/Science.1241475 |
0.612 |
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| 2013 |
Lane JR, Chubukov P, Liu W, Canals M, Cherezov V, Abagyan R, Stevens RC, Katritch V. Structure-based ligand discovery targeting orthosteric and allosteric pockets of dopamine receptors. Molecular Pharmacology. 84: 794-807. PMID 24021214 DOI: 10.1124/Mol.113.088054 |
0.676 |
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| 2013 |
Horst R, Liu JJ, Stevens RC, Wüthrich K. β₂-adrenergic receptor activation by agonists studied with ¹⁹F NMR spectroscopy. Angewandte Chemie (International Ed. in English). 52: 10762-5. PMID 23956158 DOI: 10.1002/Anie.201305286 |
0.699 |
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| 2013 |
Didenko T, Liu JJ, Horst R, Stevens RC, Wüthrich K. Fluorine-19 NMR of integral membrane proteins illustrated with studies of GPCRs. Current Opinion in Structural Biology. 23: 740-747. PMID 23932201 DOI: 10.1016/J.Sbi.2013.07.011 |
0.692 |
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| 2013 |
Shi Y, Stevens RC. Asia growth in membrane protein structure. Current Opinion in Structural Biology. 23: 481-2. PMID 23890727 DOI: 10.1016/J.Sbi.2013.07.002 |
0.311 |
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| 2013 |
Siu FY, He M, de Graaf C, Han GW, Yang D, Zhang Z, Zhou C, Xu Q, Wacker D, Joseph JS, Liu W, Lau J, Cherezov V, Katritch V, Wang MW, ... Stevens RC, et al. Structure of the human glucagon class B G-protein-coupled receptor. Nature. 499: 444-9. PMID 23863937 DOI: 10.1038/Nature12393 |
0.829 |
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| 2013 |
Tao H, Lee SC, Moeller A, Roy RS, Siu FY, Zimmermann J, Stevens RC, Potter CS, Carragher B, Zhang Q. Engineered nanostructured β-sheet peptides protect membrane proteins. Nature Methods. 10: 759-61. PMID 23817067 DOI: 10.1038/Nmeth.2533 |
0.777 |
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| 2013 |
Jacky BP, Garay PE, Dupuy J, Nelson JB, Cai B, Molina Y, Wang J, Steward LE, Broide RS, Francis J, Aoki KR, Stevens RC, Fernández-Salas E. Identification of fibroblast growth factor receptor 3 (FGFR3) as a protein receptor for botulinum neurotoxin serotype A (BoNT/A). Plos Pathogens. 9: e1003369. PMID 23696738 DOI: 10.1371/Journal.Ppat.1003369 |
0.406 |
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| 2013 |
Wang C, Wu H, Katritch V, Han GW, Huang XP, Liu W, Siu FY, Roth BL, Cherezov V, Stevens RC. Structure of the human smoothened receptor bound to an antitumour agent. Nature. 497: 338-43. PMID 23636324 DOI: 10.1038/Nature12167 |
0.833 |
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| 2013 |
Kufareva I, Stephens B, Gilliland CT, Wu B, Fenalti G, Hamel D, Stevens RC, Abagyan R, Handel TM. A novel approach to quantify G-protein-coupled receptor dimerization equilibrium using bioluminescence resonance energy transfer. Methods in Molecular Biology (Clifton, N.J.). 1013: 93-127. PMID 23625495 DOI: 10.1007/978-1-62703-426-5_7 |
0.541 |
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| 2013 |
Rosen H, Stevens RC, Hanson M, Roberts E, Oldstone MB. Sphingosine-1-phosphate and its receptors: structure, signaling, and influence. Annual Review of Biochemistry. 82: 637-62. PMID 23527695 DOI: 10.1146/Annurev-Biochem-062411-130916 |
0.635 |
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| 2013 |
Wacker D, Wang C, Katritch V, Han GW, Huang XP, Vardy E, McCorvy JD, Jiang Y, Chu M, Siu FY, Liu W, Xu HE, Cherezov V, Roth BL, Stevens RC. Structural features for functional selectivity at serotonin receptors. Science (New York, N.Y.). 340: 615-9. PMID 23519215 DOI: 10.1126/Science.1232808 |
0.824 |
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| 2013 |
Wang C, Jiang Y, Ma J, Wu H, Wacker D, Katritch V, Han GW, Liu W, Huang XP, Vardy E, McCorvy JD, Gao X, Zhou XE, Melcher K, Zhang C, ... ... Stevens RC, et al. Structural basis for molecular recognition at serotonin receptors. Science (New York, N.Y.). 340: 610-4. PMID 23519210 DOI: 10.1126/Science.1232807 |
0.826 |
|
| 2013 |
Lee SC, Bennett BC, Hong WX, Fu Y, Baker KA, Marcoux J, Robinson CV, Ward AB, Halpert JR, Stevens RC, Stout CD, Yeager MJ, Zhang Q. Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins. Proceedings of the National Academy of Sciences of the United States of America. 110: E1203-11. PMID 23479627 DOI: 10.1073/Pnas.1221442110 |
0.417 |
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| 2013 |
Pieper U, Schlessinger A, Kloppmann E, Chang GA, Chou JJ, Dumont ME, Fox BG, Fromme P, Hendrickson WA, Malkowski MG, Rees DC, Stokes DL, Stowell MH, Wiener MC, Rost B, ... ... Stevens RC, et al. Coordinating the impact of structural genomics on the human α-helical transmembrane proteome. Nature Structural & Molecular Biology. 20: 135-8. PMID 23381628 DOI: 10.1038/Nsmb.2508 |
0.552 |
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| 2013 |
Stevens RC, Cherezov V, Katritch V, Abagyan R, Kuhn P, Rosen H, Wüthrich K. The GPCR Network: a large-scale collaboration to determine human GPCR structure and function. Nature Reviews. Drug Discovery. 12: 25-34. PMID 23237917 DOI: 10.1038/Nrd3859 |
0.723 |
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| 2013 |
Katritch V, Cherezov V, Stevens RC. Structure-function of the G protein-coupled receptor superfamily. Annual Review of Pharmacology and Toxicology. 53: 531-56. PMID 23140243 DOI: 10.1146/Annurev-Pharmtox-032112-135923 |
0.696 |
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| 2013 |
Horst R, Stanczak P, Stevens RC, Wüthrich K. β2-Adrenergic receptor solutions for structural biology analyzed with microscale NMR diffusion measurements. Angewandte Chemie (International Ed. in English). 52: 331-5. PMID 23097212 DOI: 10.1002/Anie.201205474 |
0.506 |
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| 2013 |
Webb DR, Handel TM, Kretz-Rommel A, Stevens RC. Opportunities for functional selectivity in GPCR antibodies. Biochemical Pharmacology. 85: 147-52. PMID 22975405 DOI: 10.1016/J.Bcp.2012.08.021 |
0.437 |
|
| 2013 |
Jacky B, Garay P, Dupuy J, Nelson J, Cai B, Molina Y, Steward L, Broide R, Francis J, Aoki K, Stevens R, Fernández-Salas E. Identification of fibroblast growth factor receptor 3 as a protein receptor for botulinum neurotoxin serotype A Toxicon. 68: 88. DOI: 10.1016/J.Toxicon.2012.07.085 |
0.356 |
|
| 2013 |
Bennett B, Purdy M, Baker K, McIntire W, Stevens R, Zhang Q, Yeager M. X-Ray Structure of the Cx26 Gap Junction Channel and Comparison with the Cryo-EM Structure of Cx43 Biophysical Journal. 104: 42a-43a. DOI: 10.1016/J.Bpj.2012.11.272 |
0.332 |
|
| 2012 |
Santos JS, Asmar-Rovira GA, Han GW, Liu W, Syeda R, Cherezov V, Baker KA, Stevens RC, Montal M. Crystal structure of a voltage-gated K+ channel pore module in a closed state in lipid membranes. The Journal of Biological Chemistry. 287: 43063-70. PMID 23095758 DOI: 10.1074/jbc.M112.415091 |
0.341 |
|
| 2012 |
Liu W, Chun E, Thompson AA, Chubukov P, Xu F, Katritch V, Han GW, Roth CB, Heitman LH, IJzerman AP, Cherezov V, Stevens RC. Structural basis for allosteric regulation of GPCRs by sodium ions. Science (New York, N.Y.). 337: 232-6. PMID 22798613 DOI: 10.1126/Science.1219218 |
0.828 |
|
| 2012 |
Tao H, Fu Y, Thompson A, Lee SC, Mahoney N, Stevens RC, Zhang Q. Synthesis and properties of dodecyl trehaloside detergents for membrane protein studies. Langmuir : the Acs Journal of Surfaces and Colloids. 28: 11173-81. PMID 22780816 DOI: 10.1021/La3020404 |
0.399 |
|
| 2012 |
Chun E, Thompson AA, Liu W, Roth CB, Griffith MT, Katritch V, Kunken J, Xu F, Cherezov V, Hanson MA, Stevens RC. Fusion partner toolchest for the stabilization and crystallization of G protein-coupled receptors. Structure (London, England : 1993). 20: 967-76. PMID 22681902 DOI: 10.1016/J.Str.2012.04.010 |
0.824 |
|
| 2012 |
Thompson AA, Liu W, Chun E, Katritch V, Wu H, Vardy E, Huang XP, Trapella C, Guerrini R, Calo G, Roth BL, Cherezov V, Stevens RC. Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic. Nature. 485: 395-9. PMID 22596163 DOI: 10.1038/Nature11085 |
0.825 |
|
| 2012 |
Ferrero DM, Wacker D, Roque MA, Baldwin MW, Stevens RC, Liberles SD. Agonists for 13 trace amine-associated receptors provide insight into the molecular basis of odor selectivity. Acs Chemical Biology. 7: 1184-9. PMID 22545963 DOI: 10.1021/Cb300111E |
0.761 |
|
| 2012 |
Tosh DK, Phan K, Gao ZG, Gakh AA, Xu F, Deflorian F, Abagyan R, Stevens RC, Jacobson KA, Katritch V. Optimization of adenosine 5'-carboxamide derivatives as adenosine receptor agonists using structure-based ligand design and fragment screening. Journal of Medicinal Chemistry. 55: 4297-308. PMID 22486652 DOI: 10.1021/Jm300095S |
0.737 |
|
| 2012 |
Wu H, Wacker D, Mileni M, Katritch V, Han GW, Vardy E, Liu W, Thompson AA, Huang XP, Carroll FI, Mascarella SW, Westkaemper RB, Mosier PD, Roth BL, Cherezov V, ... Stevens RC, et al. Structure of the human κ-opioid receptor in complex with JDTic. Nature. 485: 327-32. PMID 22437504 DOI: 10.1038/Nature10939 |
0.827 |
|
| 2012 |
Hanson MA, Roth CB, Jo E, Griffith MT, Scott FL, Reinhart G, Desale H, Clemons B, Cahalan SM, Schuerer SC, Sanna MG, Han GW, Kuhn P, Rosen H, Stevens RC. Crystal structure of a lipid G protein-coupled receptor. Science (New York, N.Y.). 335: 851-5. PMID 22344443 DOI: 10.1126/Science.1215904 |
0.782 |
|
| 2012 |
Liu JJ, Horst R, Katritch V, Stevens RC, Wüthrich K. Biased signaling pathways in β2-adrenergic receptor characterized by 19F-NMR. Science (New York, N.Y.). 335: 1106-10. PMID 22267580 DOI: 10.1126/Science.1215802 |
0.795 |
|
| 2012 |
Deflorian F, Kumar TS, Phan K, Gao ZG, Xu F, Wu H, Katritch V, Stevens RC, Jacobson KA. Evaluation of molecular modeling of agonist binding in light of the crystallographic structure of an agonist-bound Aâ‚‚A adenosine receptor. Journal of Medicinal Chemistry. 55: 538-52. PMID 22104008 DOI: 10.1021/Jm201461Q |
0.825 |
|
| 2012 |
Katritch V, Cherezov V, Stevens RC. Diversity and modularity of G protein-coupled receptor structures. Trends in Pharmacological Sciences. 33: 17-27. PMID 22032986 DOI: 10.1016/J.Tips.2011.09.003 |
0.709 |
|
| 2012 |
Fromme P, Chapman H, Kupitz C, Hunter MS, Kirian RA, Barty A, White TA, Aquilla A, Stellato F, Beyerlein K, DePonte DP, Frank M, Schlichting I, Shoeman R, Lomb L, ... ... Stevens R, et al. Femtosecond nanocrystallography of membrane proteins opens a new era for structural biology Acta Crystallographica Section a Foundations of Crystallography. 68: s28-s28. DOI: 10.1107/S0108767312099461 |
0.334 |
|
| 2012 |
Weyand S, Shimamura T, Shiroshi M, Tsujimoto H, Winter G, Katritch V, Abagyan R, Cherezov V, Liu W, Han GW, Kobayashi T, Stevens RC, Iwata S. The structure of the human histamine H1 receptor Acta Crystallographica Section a Foundations of Crystallography. 68: s29-s29. DOI: 10.1107/S0108767312099448 |
0.649 |
|
| 2012 |
Santos JS, Asmar-Rovira G, Han G, Liu W, Syeda R, Stevens RC, Montal M. Structure of the Pore Module of a Voltage-Gated Channel in a Lipid Environment at 3.1 Å Resolution Biophysical Journal. 102: 265a. DOI: 10.1016/J.Bpj.2011.11.1459 |
0.353 |
|
| 2011 |
Stevens RC. A roadmap to membrane protein structures. Methods (San Diego, Calif.). 55: 271-2. PMID 22245712 DOI: 10.1016/J.Ymeth.2011.12.011 |
0.331 |
|
| 2011 |
Thompson AA, Liu JJ, Chun E, Wacker D, Wu H, Cherezov V, Stevens RC. GPCR stabilization using the bicelle-like architecture of mixed sterol-detergent micelles. Methods (San Diego, Calif.). 55: 310-7. PMID 22041719 DOI: 10.1016/J.Ymeth.2011.10.011 |
0.816 |
|
| 2011 |
de Graaf C, Kooistra AJ, Vischer HF, Katritch V, Kuijer M, Shiroishi M, Iwata S, Shimamura T, Stevens RC, de Esch IJ, Leurs R. Crystal structure-based virtual screening for fragment-like ligands of the human histamine H(1) receptor. Journal of Medicinal Chemistry. 54: 8195-206. PMID 22007643 DOI: 10.1021/Jm2011589 |
0.676 |
|
| 2011 |
Xu F, Stevens RC. Trapping small caffeine in a large GPCR pocket. Structure (London, England : 1993). 19: 1204-7. PMID 21893281 DOI: 10.1016/J.Str.2011.08.007 |
0.475 |
|
| 2011 |
West GM, Chien EY, Katritch V, Gatchalian J, Chalmers MJ, Stevens RC, Griffin PR. Ligand-dependent perturbation of the conformational ensemble for the GPCR β2 adrenergic receptor revealed by HDX. Structure (London, England : 1993). 19: 1424-32. PMID 21889352 DOI: 10.1016/J.Str.2011.08.001 |
0.673 |
|
| 2011 |
Kufareva I, Rueda M, Katritch V, Stevens RC, Abagyan R. Status of GPCR modeling and docking as reflected by community-wide GPCR Dock 2010 assessment. Structure (London, England : 1993). 19: 1108-26. PMID 21827947 DOI: 10.1016/J.Str.2011.05.012 |
0.664 |
|
| 2011 |
Sarkissian CN, Kang TS, Gámez A, Scriver CR, Stevens RC. Evaluation of orally administered PEGylated phenylalanine ammonia lyase in mice for the treatment of Phenylketonuria. Molecular Genetics and Metabolism. 104: 249-54. PMID 21803624 DOI: 10.1016/J.Ymgme.2011.06.016 |
0.462 |
|
| 2011 |
Shimamura T, Shiroishi M, Weyand S, Tsujimoto H, Winter G, Katritch V, Abagyan R, Cherezov V, Liu W, Han GW, Kobayashi T, Stevens RC, Iwata S. Structure of the human histamine H1 receptor complex with doxepin. Nature. 475: 65-70. PMID 21697825 DOI: 10.1038/Nature10236 |
0.656 |
|
| 2011 |
Xu F, Liu W, Hanson MA, Stevens RC, Cherezov V. Development of an Automated High Throughput LCP-FRAP Assay to Guide Membrane Protein Crystallization in Lipid Mesophases. Crystal Growth & Design. 11: 1193-1201. PMID 21660116 DOI: 10.1021/Cg101385E |
0.663 |
|
| 2011 |
Miller MT, Mileni M, Comoletti D, Stevens RC, Harel M, Taylor P. The crystal structure of the α-neurexin-1 extracellular region reveals a hinge point for mediating synaptic adhesion and function. Structure (London, England : 1993). 19: 767-78. PMID 21620717 DOI: 10.1016/J.Str.2011.03.011 |
0.786 |
|
| 2011 |
Jacobson MJ, Lin G, Tepp W, Dupuy J, Stenmark P, Stevens RC, Johnson EA. Purification, modeling, and analysis of botulinum neurotoxin subtype A5 (BoNT/A5) from Clostridium botulinum strain A661222. Applied and Environmental Microbiology. 77: 4217-22. PMID 21515732 DOI: 10.1128/Aem.00201-11 |
0.555 |
|
| 2011 |
Thompson AA, Jiao GS, Kim S, Thai A, Cregar-Hernandez L, Margosiak SA, Johnson AT, Han GW, O'Malley S, Stevens RC. Structural characterization of three novel hydroxamate-based zinc chelating inhibitors of the Clostridium botulinum serotype A neurotoxin light chain metalloprotease reveals a compact binding site resulting from 60/70 loop flexibility. Biochemistry. 50: 4019-28. PMID 21434688 DOI: 10.1021/Bi2001483 |
0.395 |
|
| 2011 |
Ezzili C, Mileni M, McGlinchey N, Long JZ, Kinsey SG, Hochstatter DG, Stevens RC, Lichtman AH, Cravatt BF, Bilsky EJ, Boger DL. Reversible competitive α-ketoheterocycle inhibitors of fatty acid amide hydrolase containing additional conformational constraints in the acyl side chain: orally active, long-acting analgesics. Journal of Medicinal Chemistry. 54: 2805-22. PMID 21428410 DOI: 10.1021/Jm101597X |
0.758 |
|
| 2011 |
Xu F, Wu H, Katritch V, Han GW, Jacobson KA, Gao ZG, Cherezov V, Stevens RC. Structure of an agonist-bound human A2A adenosine receptor. Science (New York, N.Y.). 332: 322-7. PMID 21393508 DOI: 10.1126/Science.1202793 |
0.825 |
|
| 2011 |
Mileni M, Garfunkle J, Ezzili C, Cravatt BF, Stevens RC, Boger DL. Fluoride-mediated capture of a noncovalent bound state of a reversible covalent enzyme inhibitor: X-ray crystallographic analysis of an exceptionally potent α-ketoheterocycle inhibitor of fatty acid amide hydrolase. Journal of the American Chemical Society. 133: 4092-100. PMID 21355555 DOI: 10.1021/Ja110877Y |
0.781 |
|
| 2011 |
Ezzili C, Mileni M, McGlinchey N, Long JZ, Kinsey SG, Hochstatter DG, Stevens RC, Lichtman AH, Cravatt BF, Bilsky EJ, Boger DL. alpha-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase Containing Additional Conformational Contraints in the Acyl Side Chain Journal of Medicinal Chemistry. 54: 2805-2822. DOI: 10.2210/Pdb3Oj8/Pdb |
0.734 |
|
| 2011 |
Iwata S, Shimamura T, Shiroishi M, Weyand S, Tsujimoto H, Winter G, Katritch V, Abagyan R, Cherezov V, Liu W, Han GW, Kobayashi T, Stevens RC. Molecular basis of antihistamine specificity against human histamine H1 receptor Acta Crystallographica Section a Foundations of Crystallography. 67: C17-C17. DOI: 10.1107/S0108767311099648 |
0.622 |
|
| 2011 |
Cherezov V, Wu B, Chien E, Liu W, Xu F, Stevens RC. Structural biology of G protein-coupled receptors Acta Crystallographica Section a Foundations of Crystallography. 67: C132-C132. DOI: 10.1107/S0108767311096760 |
0.539 |
|
| 2011 |
Shimamura T, Shiroishi M, Weyand S, Tsujimoto H, Winter G, Katritch V, Abagyan R, Cherezov V, Liu W, Han GW, Kobayashi T, Stevens RC, Iwata S. Structure of the human histamine H1 receptor with doxepin Acta Crystallographica Section a Foundations of Crystallography. 67: C185-C186. DOI: 10.1107/S0108767311095377 |
0.649 |
|
| 2011 |
Padilla-Morales LF, Morales-Pérez CL, De La Cruz-Rivera PC, Lopez-Cruz LM, Asmar-Rovira GA, Stevens RC, Quesada O, Lasalde-Dominicci JA. Characterization of Nicotinic Acetylcholine Receptor from Torpedo Californica Uding Lipid Analog Detergents Biophysical Journal. 100: 276a. DOI: 10.1016/J.Bpj.2010.12.1715 |
0.339 |
|
| 2010 |
Chien EY, Liu W, Zhao Q, Katritch V, Han GW, Hanson MA, Shi L, Newman AH, Javitch JA, Cherezov V, Stevens RC. Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist. Science (New York, N.Y.). 330: 1091-5. PMID 21097933 DOI: 10.1126/Science.1197410 |
0.766 |
|
| 2010 |
Wu B, Chien EY, Mol CD, Fenalti G, Liu W, Katritch V, Abagyan R, Brooun A, Wells P, Bi FC, Hamel DJ, Kuhn P, Handel TM, Cherezov V, Stevens RC. Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists. Science (New York, N.Y.). 330: 1066-71. PMID 20929726 DOI: 10.1126/Science.1194396 |
0.744 |
|
| 2010 |
Siu FY, Stevens RC. RAMP-ing up class-B GPCR ECD structural coverage. Structure (London, England : 1993). 18: 1067-8. PMID 20826331 DOI: 10.1016/J.Str.2010.08.004 |
0.813 |
|
| 2010 |
Tate CG, Stevens RC. Growth and excitement in membrane protein structural biology. Current Opinion in Structural Biology. 20: 399-400. PMID 20702086 DOI: 10.1016/J.Sbi.2010.07.002 |
0.304 |
|
| 2010 |
Stevens RC, Sancho J, Martinez A. Rescue of misfolded proteins and stabilization by small molecules. Methods in Molecular Biology (Clifton, N.J.). 648: 313-24. PMID 20700723 DOI: 10.1007/978-1-60761-756-3_22 |
0.327 |
|
| 2010 |
Wacker D, Fenalti G, Brown MA, Katritch V, Abagyan R, Cherezov V, Stevens RC. Conserved binding mode of human beta2 adrenergic receptor inverse agonists and antagonist revealed by X-ray crystallography. Journal of the American Chemical Society. 132: 11443-5. PMID 20669948 DOI: 10.1021/Ja105108Q |
0.818 |
|
| 2010 |
Cherezov V, Abola E, Stevens RC. Recent progress in the structure determination of GPCRs, a membrane protein family with high potential as pharmaceutical targets. Methods in Molecular Biology (Clifton, N.J.). 654: 141-68. PMID 20665265 DOI: 10.1007/978-1-60761-762-4_8 |
0.411 |
|
| 2010 |
Michino M, Chen J, Stevens RC, Brooks CL. FoldGPCR: structure prediction protocol for the transmembrane domain of G protein-coupled receptors from class A. Proteins. 78: 2189-201. PMID 20544957 DOI: 10.1002/Prot.22731 |
0.461 |
|
| 2010 |
Mileni M, Kamtekar S, Wood DC, Benson TE, Cravatt BF, Stevens RC. Crystal structure of fatty acid amide hydrolase bound to the carbamate inhibitor URB597: discovery of a deacylating water molecule and insight into enzyme inactivation. Journal of Molecular Biology. 400: 743-54. PMID 20493882 DOI: 10.1016/J.Jmb.2010.05.034 |
0.769 |
|
| 2010 |
Liu W, Hanson MA, Stevens RC, Cherezov V. LCP-Tm: an assay to measure and understand stability of membrane proteins in a membrane environment. Biophysical Journal. 98: 1539-48. PMID 20409473 DOI: 10.1016/J.Bpj.2009.12.4296 |
0.601 |
|
| 2010 |
Hong WX, Baker KA, Ma X, Stevens RC, Yeager M, Zhang Q. Design, synthesis, and properties of branch-chained maltoside detergents for stabilization and crystallization of integral membrane proteins: human connexin 26. Langmuir : the Acs Journal of Surfaces and Colloids. 26: 8690-6. PMID 20232919 DOI: 10.1021/La904893D |
0.308 |
|
| 2010 |
Stenmark P, Dong M, Dupuy J, Chapman ER, Stevens RC. Crystal structure of the botulinum neurotoxin type G binding domain: insight into cell surface binding. Journal of Molecular Biology. 397: 1287-97. PMID 20219474 DOI: 10.1016/J.Jmb.2010.02.041 |
0.654 |
|
| 2010 |
Jaakola VP, Lane JR, Lin JY, Katritch V, Ijzerman AP, Stevens RC. Ligand binding and subtype selectivity of the human A(2A) adenosine receptor: identification and characterization of essential amino acid residues. The Journal of Biological Chemistry. 285: 13032-44. PMID 20147292 DOI: 10.1074/Jbc.M109.096974 |
0.808 |
|
| 2010 |
Dong J, Thompson AA, Fan Y, Lou J, Conrad F, Ho M, Pires-Alves M, Wilson BA, Stevens RC, Marks JD. A single-domain llama antibody potently inhibits the enzymatic activity of botulinum neurotoxin by binding to the non-catalytic alpha-exosite binding region. Journal of Molecular Biology. 397: 1106-18. PMID 20138889 DOI: 10.1016/J.Jmb.2010.01.070 |
0.343 |
|
| 2010 |
Katritch V, Jaakola VP, Lane JR, Lin J, Ijzerman AP, Yeager M, Kufareva I, Stevens RC, Abagyan R. Structure-based discovery of novel chemotypes for adenosine A(2A) receptor antagonists. Journal of Medicinal Chemistry. 53: 1799-809. PMID 20095623 DOI: 10.1021/Jm901647P |
0.802 |
|
| 2010 |
Zhang X, Chien EY, Chalmers MJ, Pascal BD, Gatchalian J, Stevens RC, Griffin PR. Dynamics of the beta2-adrenergic G-protein coupled receptor revealed by hydrogen-deuterium exchange. Analytical Chemistry. 82: 1100-8. PMID 20058880 DOI: 10.1021/Ac902484P |
0.443 |
|
| 2010 |
Mileni M, Garfunkle J, Ezzili C, Kimball FS, Cravatt BF, Stevens RC, Boger DL. X-ray crystallographic analysis of alpha-ketoheterocycle inhibitors bound to a humanized variant of fatty acid amide hydrolase. Journal of Medicinal Chemistry. 53: 230-40. PMID 19924997 DOI: 10.1021/Jm9012196 |
0.776 |
|
| 2010 |
Kang TS, Wang L, Sarkissian CN, Gámez A, Scriver CR, Stevens RC. Converting an injectable protein therapeutic into an oral form: phenylalanine ammonia lyase for phenylketonuria. Molecular Genetics and Metabolism. 99: 4-9. PMID 19793667 DOI: 10.1016/J.Ymgme.2009.09.002 |
0.489 |
|
| 2010 |
Padilla-Morales LF, Morales-Perez CL, De La Cruz-Rivera P, Lopez-Cruz LM, Asmar-Rovira G, Stevens R, Quesada O, Lasalde-Dominicci JA. Efficient Isolation and Characterization of Nicotinic Acetylcholine Receptor from Torpedo Californica using Lipid Analog Detergents Biophysical Journal. 98: 132a-133a. DOI: 10.1016/J.Bpj.2009.12.716 |
0.323 |
|
| 2010 |
Jaakola VP, Stevens RC. G protein-coupled receptor structures Handbook of Cell Signaling, 2/E. 1: 129-138. DOI: 10.1016/B978-0-12-374145-5.00020-6 |
0.729 |
|
| 2009 |
Kang TS, Stevens RC. Structural aspects of therapeutic enzymes to treat metabolic disorders. Human Mutation. 30: 1591-610. PMID 19790257 DOI: 10.1002/Humu.21111 |
0.53 |
|
| 2009 |
Mileni M, Garfunkle J, DeMartino JK, Cravatt BF, Boger DL, Stevens RC. Binding and inactivation mechanism of a humanized fatty acid amide hydrolase by alpha-ketoheterocycle inhibitors revealed from cocrystal structures. Journal of the American Chemical Society. 131: 10497-506. PMID 19722626 DOI: 10.1021/Ja902694N |
0.782 |
|
| 2009 |
Hanson MA, Stevens RC. Retraction: Cocrystal structure of synaptobrevin-II bound to botulinum neurotoxin type B at 2.0 A resolution. Nature Structural & Molecular Biology. 16: 795. PMID 19578378 DOI: 10.1038/Nsmb0709-795 |
0.554 |
|
| 2009 |
Cherezov V, Hanson MA, Griffith MT, Hilgart MC, Sanishvili R, Nagarajan V, Stepanov S, Fischetti RF, Kuhn P, Stevens RC. Rastering strategy for screening and centring of microcrystal samples of human membrane proteins with a sub-10 microm size X-ray synchrotron beam. Journal of the Royal Society, Interface / the Royal Society. 6: S587-97. PMID 19535414 DOI: 10.1098/Rsif.2009.0142.Focus |
0.594 |
|
| 2009 |
Michino M, Abola E, Brooks CL, Dixon JS, Moult J, Stevens RC. Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008. Nature Reviews. Drug Discovery. 8: 455-63. PMID 19461661 DOI: 10.1038/Nrd2877 |
0.486 |
|
| 2009 |
Ahn K, Johnson DS, Mileni M, Beidler D, Long JZ, McKinney MK, Weerapana E, Sadagopan N, Liimatta M, Smith SE, Lazerwith S, Stiff C, Kamtekar S, Bhattacharya K, Zhang Y, ... ... Stevens RC, et al. Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain. Chemistry & Biology. 16: 411-20. PMID 19389627 DOI: 10.1016/J.Chembiol.2009.02.013 |
0.756 |
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| 2009 |
Hanson MA, Stevens RC. Discovery of new GPCR biology: one receptor structure at a time. Structure (London, England : 1993). 17: 8-14. PMID 19141277 DOI: 10.1016/J.Str.2008.12.003 |
0.648 |
|
| 2008 |
Cherezov V, Liu J, Griffith M, Hanson MA, Stevens RC. LCP-FRAP Assay for Pre-Screening Membrane Proteins for in Meso Crystallization. Crystal Growth & Design. 8: 4307-4315. PMID 19234616 DOI: 10.1021/Cg800778J |
0.724 |
|
| 2008 |
Barglow KT, Saikatendu KS, Bracey MH, Huey R, Morris GM, Olson AJ, Stevens RC, Cravatt BF. Functional proteomic and structural insights into molecular recognition in the nitrilase family enzymes. Biochemistry. 47: 13514-23. PMID 19053248 DOI: 10.1021/Bi801786Y |
0.342 |
|
| 2008 |
Holden LG, Prochnow C, Chang YP, Bransteitter R, Chelico L, Sen U, Stevens RC, Goodman MF, Chen XS. Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications. Nature. 456: 121-4. PMID 18849968 DOI: 10.1038/Nature07357 |
0.403 |
|
| 2008 |
Jaakola VP, Griffith MT, Hanson MA, Cherezov V, Chien EY, Lane JR, Ijzerman AP, Stevens RC. The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist. Science (New York, N.Y.). 322: 1211-7. PMID 18832607 DOI: 10.1126/Science.1164772 |
0.828 |
|
| 2008 |
Mileni M, Johnson DS, Wang Z, Everdeen DS, Liimatta M, Pabst B, Bhattacharya K, Nugent RA, Kamtekar S, Cravatt BF, Ahn K, Stevens RC. Structure-guided inhibitor design for human FAAH by interspecies active site conversion. Proceedings of the National Academy of Sciences of the United States of America. 105: 12820-4. PMID 18753625 DOI: 10.1073/Pnas.0806121105 |
0.78 |
|
| 2008 |
Stenmark P, Dupuy J, Imamura A, Kiso M, Stevens RC. Crystal structure of botulinum neurotoxin type A in complex with the cell surface co-receptor GT1b-insight into the toxin-neuron interaction. Plos Pathogens. 4: e1000129. PMID 18704164 DOI: 10.1371/Journal.Ppat.1000129 |
0.689 |
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| 2008 |
Slaymaker IM, Bracey M, Mileni M, Garfunkle J, Cravatt BF, Boger DL, Stevens RC. Correlation of inhibitor effects on enzyme activity and thermal stability for the integral membrane protein fatty acid amide hydrolase. Bioorganic & Medicinal Chemistry Letters. 18: 5847-50. PMID 18644727 DOI: 10.1016/J.Bmcl.2008.06.086 |
0.742 |
|
| 2008 |
Asmar-Rovira GA, Asseo-GarcÃa AM, Quesada O, Hanson MA, Cheng A, Nogueras C, Lasalde-Dominicci JA, Stevens RC. Biophysical and ion channel functional characterization of the Torpedo californica nicotinic acetylcholine receptor in varying detergent-lipid environments. The Journal of Membrane Biology. 223: 13-26. PMID 18581036 DOI: 10.1007/S00232-008-9107-7 |
0.54 |
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| 2008 |
Wang L, Gamez A, Archer H, Abola EE, Sarkissian CN, Fitzpatrick P, Wendt D, Zhang Y, Vellard M, Bliesath J, Bell SM, Lemontt JF, Scriver CR, Stevens RC. Structural and biochemical characterization of the therapeutic Anabaena variabilis phenylalanine ammonia lyase. Journal of Molecular Biology. 380: 623-35. PMID 18556022 DOI: 10.1016/J.Jmb.2008.05.025 |
0.365 |
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| 2008 |
Hanson MA, Cherezov V, Griffith MT, Roth CB, Jaakola VP, Chien EY, Velasquez J, Kuhn P, Stevens RC. A specific cholesterol binding site is established by the 2.8 A structure of the human beta2-adrenergic receptor. Structure (London, England : 1993). 16: 897-905. PMID 18547522 DOI: 10.1016/J.Str.2008.05.001 |
0.831 |
|
| 2008 |
Ng JD, Stevens RC, Kuhn P. Protein crystallization in restricted geometry: advancing old ideas for modern times in structural proteomics. Methods in Molecular Biology (Clifton, N.J.). 426: 363-76. PMID 18542876 DOI: 10.1007/978-1-60327-058-8_23 |
0.358 |
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| 2008 |
Zhang Q, Horst R, Geralt M, Ma X, Hong WX, Finn MG, Stevens RC, Wüthrich K. Microscale NMR screening of new detergents for membrane protein structural biology. Journal of the American Chemical Society. 130: 7357-63. PMID 18479092 DOI: 10.1021/Ja077863D |
0.482 |
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| 2008 |
Neuman BW, Joseph JS, Saikatendu KS, Serrano P, Chatterjee A, Johnson MA, Liao L, Klaus JP, Yates JR, Wüthrich K, Stevens RC, Buchmeier MJ, Kuhn P. Proteomics analysis unravels the functional repertoire of coronavirus nonstructural protein 3. Journal of Virology. 82: 5279-94. PMID 18367524 DOI: 10.1128/Jvi.02631-07 |
0.467 |
|
| 2008 |
Alexandrov AI, Mileni M, Chien EY, Hanson MA, Stevens RC. Microscale fluorescent thermal stability assay for membrane proteins. Structure (London, England : 1993). 16: 351-9. PMID 18334210 DOI: 10.1016/J.Str.2008.02.004 |
0.799 |
|
| 2008 |
Gräslund S, Nordlund P, Weigelt J, Hallberg BM, Bray J, Gileadi O, Knapp S, Oppermann U, Arrowsmith C, Hui R, Ming J, dhe-Paganon S, ... ... Stevens RC, et al. Protein production and purification. Nature Methods. 5: 135-46. PMID 18235434 DOI: 10.1038/Nmeth.F.202 |
0.482 |
|
| 2008 |
Roth CB, Hanson MA, Stevens RC. Stabilization of the human beta2-adrenergic receptor TM4-TM3-TM5 helix interface by mutagenesis of Glu122(3.41), a critical residue in GPCR structure. Journal of Molecular Biology. 376: 1305-19. PMID 18222471 DOI: 10.1016/J.Jmb.2007.12.028 |
0.748 |
|
| 2008 |
Ng JD, Clark PJ, Stevens RC, Kuhn P. In situ X-ray analysis of protein crystals in low-birefringent and X-ray transmissive plastic microchannels. Acta Crystallographica. Section D, Biological Crystallography. 64: 189-97. PMID 18219119 DOI: 10.1107/S0907444907060064 |
0.318 |
|
| 2008 |
Jauch R, Ng CK, Saikatendu KS, Stevens RC, Kolatkar PR. Crystal structure and DNA binding of the homeodomain of the stem cell transcription factor Nanog. Journal of Molecular Biology. 376: 758-70. PMID 18177668 DOI: 10.1016/J.Jmb.2007.11.091 |
0.341 |
|
| 2008 |
Mathews II, McMullan D, Miller MD, Canaves JM, Elsliger MA, Floyd R, Grzechnik SK, Jaroszewski L, Klock HE, Koesema E, Kovarik JS, Kreusch A, Kuhn P, McPhillips TM, Morse AT, ... ... Stevens RC, et al. Crystal structure of 2-keto-3-deoxygluconate kinase (TM0067) from Thermotoga maritima at 2.05 A resolution. Proteins. 70: 603-8. PMID 18004772 DOI: 10.1002/Prot.21842 |
0.344 |
|
| 2008 |
Ester F, Patton G, Birgitte J, Jerome D, Joanne W, Jeremy N, Stevens RC, Roger AK. Identification of the fibroblast growth factor receptor FGFR3 as a component of the receptor complex for Botulinum Neurotoxin Type A Toxicon. 51: 3. DOI: 10.1016/J.Toxicon.2008.04.008 |
0.415 |
|
| 2007 |
Stevens RC. Generation of protein structures for the 21(st) century. Structure (London, England : 1993). 15: 1517-9. PMID 18073098 DOI: 10.1016/J.Str.2007.11.003 |
0.384 |
|
| 2007 |
Cherezov V, Rosenbaum DM, Hanson MA, Rasmussen SG, Thian FS, Kobilka TS, Choi HJ, Kuhn P, Weis WI, Kobilka BK, Stevens RC. High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor. Science (New York, N.Y.). 318: 1258-65. PMID 17962520 DOI: 10.1126/Science.1150577 |
0.67 |
|
| 2007 |
Rosenbaum DM, Cherezov V, Hanson MA, Rasmussen SG, Thian FS, Kobilka TS, Choi HJ, Yao XJ, Weis WI, Stevens RC, Kobilka BK. GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function. Science (New York, N.Y.). 318: 1266-73. PMID 17962519 DOI: 10.1126/Science.1150609 |
0.665 |
|
| 2007 |
Serrano P, Johnson MA, Almeida MS, Horst R, Herrmann T, Joseph JS, Neuman BW, Subramanian V, Saikatendu KS, Buchmeier MJ, Stevens RC, Kuhn P, Wüthrich K. Nuclear magnetic resonance structure of the N-terminal domain of nonstructural protein 3 from the severe acute respiratory syndrome coronavirus. Journal of Virology. 81: 12049-60. PMID 17728234 DOI: 10.1128/Jvi.00969-07 |
0.495 |
|
| 2007 |
Hanson MA, Brooun A, Baker KA, Jaakola VP, Roth C, Chien EY, Alexandrov A, Velasquez J, Davis L, Griffith M, Moy K, Ganser-Pornillos BK, Hua Y, Kuhn P, Ellis S, ... ... Stevens RC, et al. Profiling of membrane protein variants in a baculovirus system by coupling cell-surface detection with small-scale parallel expression. Protein Expression and Purification. 56: 85-92. PMID 17723307 DOI: 10.1016/J.Pep.2007.06.003 |
0.786 |
|
| 2007 |
Zhang Q, Ma X, Ward A, Hong WX, Jaakola VP, Stevens RC, Finn MG, Chang G. Designing facial amphiphiles for the stabilization of integral membrane proteins. Angewandte Chemie (International Ed. in English). 46: 7023-5. PMID 17691085 DOI: 10.1002/Anie.200701556 |
0.678 |
|
| 2007 |
Gámez A, Wang L, Sarkissian CN, Wendt D, Fitzpatrick P, Lemontt JF, Scriver CR, Stevens RC. Structure-based epitope and PEGylation sites mapping of phenylalanine ammonia-lyase for enzyme substitution treatment of phenylketonuria. Molecular Genetics and Metabolism. 91: 325-34. PMID 17560821 DOI: 10.1016/J.Ymgme.2007.04.015 |
0.312 |
|
| 2007 |
Joseph JS, Saikatendu KS, Subramanian V, Neuman BW, Buchmeier MJ, Stevens RC, Kuhn P. Crystal structure of a monomeric form of severe acute respiratory syndrome coronavirus endonuclease nsp15 suggests a role for hexamerization as an allosteric switch. Journal of Virology. 81: 6700-8. PMID 17409150 DOI: 10.1128/Jvi.02817-06 |
0.369 |
|
| 2007 |
Saikatendu KS, Joseph JS, Subramanian V, Neuman BW, Buchmeier MJ, Stevens RC, Kuhn P. Ribonucleocapsid formation of severe acute respiratory syndrome coronavirus through molecular action of the N-terminal domain of N protein. Journal of Virology. 81: 3913-21. PMID 17229691 DOI: 10.1128/Jvi.02236-06 |
0.326 |
|
| 2007 |
Garcia-Rodriguez C, Levy R, Arndt JW, Forsyth CM, Razai A, Lou J, Geren I, Stevens RC, Marks JD. Molecular evolution of antibody cross-reactivity for two subtypes of type A botulinum neurotoxin. Nature Biotechnology. 25: 107-16. PMID 17173035 DOI: 10.1038/Nbt1269 |
0.309 |
|
| 2007 |
Stevens RC, Yates JR. Proteomics: You say functional, I say structural Journal of Proteome Research. 6: 927. DOI: 10.1021/Pr070726V |
0.334 |
|
| 2006 |
Chai Q, Arndt JW, Dong M, Tepp WH, Johnson EA, Chapman ER, Stevens RC. Structural basis of cell surface receptor recognition by botulinum neurotoxin B. Nature. 444: 1096-100. PMID 17167418 DOI: 10.1038/Nature05411 |
0.442 |
|
| 2006 |
Kosloff M, Han GW, Krishna SS, Schwarzenbacher R, Fasnacht M, Elsliger MA, Abdubek P, Agarwalla S, Ambing E, Astakhova T, Axelrod HL, Canaves JM, Carlton D, Chiu HJ, Clayton T, ... ... Stevens RC, et al. Comparative structural analysis of a novel glutathioneS-transferase (ATU5508) from Agrobacterium tumefaciens at 2.0 A resolution. Proteins. 65: 527-37. PMID 16988933 DOI: 10.1002/Prot.21130 |
0.583 |
|
| 2006 |
Xu Q, Krishna SS, McMullan D, Schwarzenbacher R, Miller MD, Abdubek P, Agarwalla S, Ambing E, Astakhova T, Axelrod HL, Canaves JM, Carlton D, Chiu HJ, Clayton T, DiDonato M, ... ... Stevens RC, et al. Crystal structure of an ORFan protein (TM1622) from Thermotoga maritima at 1.75 A resolution reveals a fold similar to the Ran-binding protein Mog1p. Proteins. 65: 777-82. PMID 16948158 DOI: 10.1002/Prot.21015 |
0.407 |
|
| 2006 |
Joseph JS, Saikatendu KS, Subramanian V, Neuman BW, Brooun A, Griffith M, Moy K, Yadav MK, Velasquez J, Buchmeier MJ, Stevens RC, Kuhn P. Crystal structure of nonstructural protein 10 from the severe acute respiratory syndrome coronavirus reveals a novel fold with two zinc-binding motifs. Journal of Virology. 80: 7894-901. PMID 16873246 DOI: 10.1128/Jvi.00467-06 |
0.366 |
|
| 2006 |
Mathews II, Krishna SS, Schwarzenbacher R, McMullan D, Jaroszewski L, Miller MD, Abdubek P, Agarwalla S, Ambing E, Axelrod HL, Canaves JM, Carlton D, Chiu HJ, Clayton T, DiDonato M, ... ... Stevens RC, et al. Crystal structure of phosphoribosylformyl-glycinamidine synthase II, PurS subunit (TM1244) from Thermotoga maritima at 1.90 A resolution. Proteins. 65: 249-54. PMID 16865708 DOI: 10.1002/Prot.21024 |
0.355 |
|
| 2006 |
Schwarzenbacher R, McMullan D, Krishna SS, Xu Q, Miller MD, Canaves JM, Elsliger MA, Floyd R, Grzechnik SK, Jaroszewski L, Klock HE, Koesema E, Kovarik JS, Kreusch A, Kuhn P, ... ... Stevens RC, et al. Crystal structure of a glycerate kinase (TM1585) from Thermotoga maritima at 2.70 A resolution reveals a new fold. Proteins. 65: 243-8. PMID 16865707 DOI: 10.1002/Prot.21058 |
0.358 |
|
| 2006 |
Xu Q, Schwarzenbacher R, Krishna SS, McMullan D, Agarwalla S, Quijano K, Abdubek P, Ambing E, Axelrod H, Biorac T, Canaves JM, Chiu HJ, Elsliger MA, Grittini C, Grzechnik SK, ... ... Stevens RC, et al. Crystal structure of acireductone dioxygenase (ARD) from Mus musculus at 2.06 angstrom resolution. Proteins. 64: 808-13. PMID 16783794 DOI: 10.1002/Prot.20947 |
0.373 |
|
| 2006 |
Han GW, Sri Krishna S, Schwarzenbacher R, McMullan D, Ginalski K, Elsliger MA, Brittain SM, Abdubek P, Agarwalla S, Ambing E, Astakhova T, Axelrod H, Canaves JM, Chiu HJ, DiDonato M, ... ... Stevens RC, et al. Crystal structure of the ApbE protein (TM1553) from Thermotoga maritima at 1.58 A resolution. Proteins. 64: 1083-90. PMID 16779835 DOI: 10.1002/Prot.20950 |
0.389 |
|
| 2006 |
Ratia K, Saikatendu KS, Santarsiero BD, Barretto N, Baker SC, Stevens RC, Mesecar AD. Severe acute respiratory syndrome coronavirus papain-like protease: structure of a viral deubiquitinating enzyme. Proceedings of the National Academy of Sciences of the United States of America. 103: 5717-22. PMID 16581910 DOI: 10.1073/Pnas.0510851103 |
0.687 |
|
| 2006 |
Mathews II, Krishna SS, Schwarzenbacher R, McMullan D, Abdubek P, Ambing E, Canaves JM, Chiu HJ, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, Grzechnik SK, Hale J, ... ... Stevens RC, et al. Crystal structure of phosphoribosylformylglycinamidine synthase II (smPurL) from Thermotoga maritima at 2.15 A resolution. Proteins. 63: 1106-11. PMID 16544324 DOI: 10.1002/Prot.20650 |
0.348 |
|
| 2006 |
Jin KK, Krishna SS, Schwarzenbacher R, McMullan D, Abdubek P, Agarwalla S, Ambing E, Axelrod H, Canaves JM, Chiu HJ, Deacon AM, DiDonato M, Elsliger MA, Feuerhelm J, Godzik A, ... ... Stevens RC, et al. Crystal structure of TM1367 from Thermotoga maritima at 1.90 A resolution reveals an atypical member of the cyclophilin (peptidylprolyl isomerase) fold. Proteins. 63: 1112-8. PMID 16544291 DOI: 10.1002/Prot.20894 |
0.389 |
|
| 2006 |
Arndt JW, Chai Q, Christian T, Stevens RC. Structure of botulinum neurotoxin type D light chain at 1.65 A resolution: repercussions for VAMP-2 substrate specificity. Biochemistry. 45: 3255-62. PMID 16519520 DOI: 10.1021/Bi052518R |
0.38 |
|
| 2006 |
DiDonato M, Krishna SS, Schwarzenbacher R, McMullan D, Jaroszewski L, Miller MD, Abdubek P, Agarwalla S, Ambing E, Axelrod H, Biorac T, Chiu HJ, Deacon AM, Elsliger MA, Feuerhelm J, ... ... Stevens RC, et al. Crystal structure of a single-stranded DNA-binding protein (TM0604) from Thermotoga maritima at 2.60 A resolution. Proteins. 63: 256-60. PMID 16435371 DOI: 10.1002/Prot.20841 |
0.367 |
|
| 2006 |
Xu Q, Schwarzenbacher R, McMullan D, Abdubek P, Agarwalla S, Ambing E, Axelrod H, Biorac T, Canaves JM, Chiu HJ, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, ... ... Stevens RC, et al. Crystal structure of virulence factor CJ0248 from Campylobacter jejuni at 2.25 A resolution reveals a new fold. Proteins. 62: 292-6. PMID 16287129 DOI: 10.1002/Prot.20611 |
0.358 |
|
| 2005 |
Yadav MK, Gerdts CJ, Sanishvili R, Smith WW, Roach LS, Ismagilov RF, Kuhn P, Stevens RC. In situ data collection and structure refinement from microcapillary protein crystallization. Journal of Applied Crystallography. 38: 900-905. PMID 17468785 DOI: 10.1107/S002188980502649X |
0.351 |
|
| 2005 |
Collins B, Stevens RC, Page R. Crystallization Optimum Solubility Screening: using crystallization results to identify the optimal buffer for protein crystal formation. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 61: 1035-8. PMID 16511228 DOI: 10.1107/S1744309105035244 |
0.536 |
|
| 2005 |
Peti W, Page R, Moy K, O'Neil-Johnson M, Wilson IA, Stevens RC, Wüthrich K. Towards miniaturization of a structural genomics pipeline using micro-expression and microcoil NMR. Journal of Structural and Functional Genomics. 6: 259-67. PMID 16283429 DOI: 10.1007/S10969-005-9000-X |
0.618 |
|
| 2005 |
Saikatendu KS, Joseph JS, Subramanian V, Clayton T, Griffith M, Moy K, Velasquez J, Neuman BW, Buchmeier MJ, Stevens RC, Kuhn P. Structural basis of severe acute respiratory syndrome coronavirus ADP-ribose-1''-phosphate dephosphorylation by a conserved domain of nsP3. Structure (London, England : 1993). 13: 1665-75. PMID 16271890 DOI: 10.1016/J.Str.2005.07.022 |
0.353 |
|
| 2005 |
Klock HE, Schwarzenbacher R, Xu Q, McMullan D, Abdubek P, Ambing E, Axelrod H, Biorac T, Canaves JM, Chiu HJ, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, ... ... Stevens RC, et al. Crystal structure of a conserved hypothetical protein (gi: 13879369) from Mouse at 1.90 A resolution reveals a new fold. Proteins. 61: 1132-6. PMID 16224779 DOI: 10.1002/Prot.20610 |
0.396 |
|
| 2005 |
Page R, Deacon AM, Lesley SA, Stevens RC. Shotgun crystallization strategy for structural genomics II: crystallization conditions that produce high resolution structures for T. maritima proteins. Journal of Structural and Functional Genomics. 6: 209-17. PMID 16211521 DOI: 10.1007/S10969-005-1916-7 |
0.559 |
|
| 2005 |
Peti W, Johnson MA, Herrmann T, Neuman BW, Buchmeier MJ, Nelson M, Joseph J, Page R, Stevens RC, Kuhn P, Wüthrich K. Structural genomics of the severe acute respiratory syndrome coronavirus: nuclear magnetic resonance structure of the protein nsP7. Journal of Virology. 79: 12905-13. PMID 16188992 DOI: 10.1128/Jvi.79.20.12905-12913.2005 |
0.581 |
|
| 2005 |
Jaroszewski L, Schwarzenbacher R, McMullan D, Abdubek P, Agarwalla S, Ambing E, Axelrod H, Biorac T, Canaves JM, Chiu HJ, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, ... ... Stevens RC, et al. Crystal structure of Hsp33 chaperone (TM1394) from Thermotoga maritima at 2.20 A resolution. Proteins. 61: 669-73. PMID 16167343 DOI: 10.1002/Prot.20542 |
0.356 |
|
| 2005 |
Chappie JS, Cànaves JM, Han GW, Rife CL, Xu Q, Stevens RC. The structure of a eukaryotic nicotinic acid phosphoribosyltransferase reveals structural heterogeneity among type II PRTases. Structure (London, England : 1993). 13: 1385-96. PMID 16154095 DOI: 10.1016/J.Str.2005.05.016 |
0.366 |
|
| 2005 |
Rife C, Schwarzenbacher R, McMullan D, Abdubek P, Ambing E, Axelrod H, Biorac T, Canaves JM, Chiu HJ, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, Grzechnik SK, ... ... Stevens RC, et al. Crystal structure of a putative modulator of DNA gyrase (pmbA) from Thermotoga maritima at 1.95 A resolution reveals a new fold. Proteins. 61: 444-8. PMID 16104019 DOI: 10.1002/Prot.20468 |
0.347 |
|
| 2005 |
Rife C, Schwarzenbacher R, McMullan D, Abdubek P, Ambing E, Axelrod H, Biorac T, Canaves JM, Chiu HJ, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, Grzechnik SK, ... ... Stevens RC, et al. Crystal structure of the global regulatory protein CsrA from Pseudomonas putida at 2.05 A resolution reveals a new fold. Proteins. 61: 449-53. PMID 16104018 DOI: 10.1002/Prot.20502 |
0.389 |
|
| 2005 |
Ricci JS, Stevens RC, McMullan RK, Klooster WT. Structure of strontium hydroxide octahydrate, Sr(OH)2.8H2O, at 20, 100 and 200 K from neutron diffraction. Acta Crystallographica. Section B, Structural Science. 61: 381-6. PMID 16041087 DOI: 10.1107/S0108768105013480 |
0.697 |
|
| 2005 |
Arndt JW, Yu W, Bi F, Stevens RC. Crystal structure of botulinum neurotoxin type G light chain: serotype divergence in substrate recognition. Biochemistry. 44: 9574-80. PMID 16008342 DOI: 10.1021/Bi0505924 |
0.413 |
|
| 2005 |
Wang L, Gamez A, Sarkissian CN, Straub M, Patch MG, Han GW, Striepeke S, Fitzpatrick P, Scriver CR, Stevens RC. Structure-based chemical modification strategy for enzyme replacement treatment of phenylketonuria. Molecular Genetics and Metabolism. 86: 134-40. PMID 16006165 DOI: 10.1016/J.Ymgme.2005.05.012 |
0.317 |
|
| 2005 |
Han GW, Schwarzenbacher R, McMullan D, Abdubek P, Ambing E, Axelrod H, Biorac T, Canaves JM, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, ... ... Stevens RC, et al. Crystal structure of an Apo mRNA decapping enzyme (DcpS) from Mouse at 1.83 A resolution. Proteins. 60: 797-802. PMID 16001405 DOI: 10.1002/Prot.20467 |
0.336 |
|
| 2005 |
Mathews I, Schwarzenbacher R, McMullan D, Abdubek P, Ambing E, Axelrod H, Biorac T, Canaves JM, Chiu HJ, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, Grzechnik SK, ... ... Stevens RC, et al. Crystal structure of S-adenosylmethionine:tRNA ribosyltransferase-isomerase (QueA) from Thermotoga maritima at 2.0 A resolution reveals a new fold. Proteins. 59: 869-74. PMID 15822125 DOI: 10.1002/Prot.20419 |
0.367 |
|
| 2005 |
Levin I, Miller MD, Schwarzenbacher R, McMullan D, Abdubek P, Ambing E, Biorac T, Cambell J, Canaves JM, Chiu HJ, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, ... ... Stevens RC, et al. Crystal structure of an indigoidine synthase A (IndA)-like protein (TM1464) from Thermotoga maritima at 1.90 A resolution reveals a new fold. Proteins. 59: 864-8. PMID 15822122 DOI: 10.1002/Prot.20420 |
0.583 |
|
| 2005 |
Arndt JW, Gu J, Jaroszewski L, Schwarzenbacher R, Hanson MA, Lebeda FJ, Stevens RC. The structure of the neurotoxin-associated protein HA33/A from Clostridium botulinum suggests a reoccurring beta-trefoil fold in the progenitor toxin complex. Journal of Molecular Biology. 346: 1083-93. PMID 15701519 DOI: 10.1016/J.Jmb.2004.12.039 |
0.577 |
|
| 2005 |
Page R, Peti W, Wilson IA, Stevens RC, Wüthrich K. NMR screening and crystal quality of bacterially expressed prokaryotic and eukaryotic proteins in a structural genomics pipeline. Proceedings of the National Academy of Sciences of the United States of America. 102: 1901-5. PMID 15677718 DOI: 10.1073/Pnas.0408490102 |
0.633 |
|
| 2005 |
Han GW, Schwarzenbacher R, Page R, Jaroszewski L, Abdubek P, Ambing E, Biorac T, Canaves JM, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, ... ... Stevens RC, et al. Crystal structure of an alanine-glyoxylate aminotransferase from Anabaena sp. at 1.70 A resolution reveals a noncovalently linked PLP cofactor. Proteins. 58: 971-5. PMID 15657930 DOI: 10.1002/Prot.20360 |
0.558 |
|
| 2005 |
Xu Q, Schwarzenbacher R, McMullan D, Abdubek P, Ambing E, Biorac T, Canaves JM, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, Grzechnik SK, ... ... Stevens RC, et al. Crystal structure of a formiminotetrahydrofolate cyclodeaminase (TM1560) from Thermotoga maritima at 2.80 A resolution reveals a new fold. Proteins. 58: 976-81. PMID 15651027 DOI: 10.1002/Prot.20364 |
0.57 |
|
| 2005 |
Arndt JW, Schwarzenbacher R, Page R, Abdubek P, Ambing E, Biorac T, Canaves JM, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, Grzechnik SK, ... ... Stevens RC, et al. Crystal structure of an alpha/beta serine hydrolase (YDR428C) from Saccharomyces cerevisiae at 1.85 A resolution. Proteins. 58: 755-8. PMID 15624212 DOI: 10.1002/Prot.20336 |
0.521 |
|
| 2005 |
Abola EE, Kuhn P, Stevens R. Miniaturization in structural biology pipelines Acta Crystallographica Section a Foundations of Crystallography. 61: c150-c150. DOI: 10.1107/S0108767305093621 |
0.357 |
|
| 2005 |
Arndt JW, Yu W, Bi F, Stevens RC. Crystal structure of botulinum neurotoxin type G light chain Acta Crystallographica Section a Foundations of Crystallography. 61: c254-c254. DOI: 10.1107/S0108767305089142 |
0.327 |
|
| 2005 |
Carter DC, Rhodes P, McRee DE, Tari LW, Dougan DR, Snell G, Abola E, Stevens RC. Reduction in diffuso-convective disturbances in nanovolume protein crystallization experiments Journal of Applied Crystallography. 38: 87-90. DOI: 10.1107/S0021889804028055 |
0.304 |
|
| 2004 |
Erlandsen H, Pey AL, Gámez A, Pérez B, Desviat LR, Aguado C, Koch R, Surendran S, Tyring S, Matalon R, Scriver CR, Ugarte M, Martínez A, Stevens RC. Correction of kinetic and stability defects by tetrahydrobiopterin in phenylketonuria patients with certain phenylalanine hydroxylase mutations. Proceedings of the National Academy of Sciences of the United States of America. 101: 16903-8. PMID 15557004 DOI: 10.1073/Pnas.0407256101 |
0.328 |
|
| 2004 |
Canaves JM, Page R, Wilson IA, Stevens RC. Protein biophysical properties that correlate with crystallization success in Thermotoga maritima: maximum clustering strategy for structural genomics. Journal of Molecular Biology. 344: 977-91. PMID 15544807 DOI: 10.1016/J.Jmb.2004.09.076 |
0.561 |
|
| 2004 |
Page R, Moy K, Sims EC, Velasquez J, McManus B, Grittini C, Clayton TL, Stevens RC. Scalable high-throughput micro-expression device for recombinant proteins. Biotechniques. 37: 364, 366, 368 passim. PMID 15470889 DOI: 10.2144/04373Bm05 |
0.484 |
|
| 2004 |
Miller MD, Schwarzenbacher R, von Delft F, Abdubek P, Ambing E, Biorac T, Brinen LS, Canaves JM, Cambell J, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, Eshagi S, ... ... Stevens RC, et al. Crystal structure of a tandem cystathionine-beta-synthase (CBS) domain protein (TM0935) from Thermotoga maritima at 1.87 A resolution. Proteins. 57: 213-7. PMID 15326606 DOI: 10.1002/Prot.20024 |
0.55 |
|
| 2004 |
Page R, Stevens RC. Crystallization data mining in structural genomics: using positive and negative results to optimize protein crystallization screens. Methods (San Diego, Calif.). 34: 373-89. PMID 15325655 DOI: 10.1016/J.Ymeth.2004.03.026 |
0.529 |
|
| 2004 |
Levin I, Schwarzenbacher R, McMullan D, Abdubek P, Ambing E, Biorac T, Cambell J, Canaves JM, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, ... ... Stevens RC, et al. Crystal structure of a putative NADPH-dependent oxidoreductase (GI: 18204011) from mouse at 2.10 A resolution. Proteins. 56: 629-33. PMID 15229897 DOI: 10.1002/Prot.20163 |
0.567 |
|
| 2004 |
Xu Q, Schwarzenbacher R, Page R, Sims E, Abdubek P, Ambing E, Biorac T, Brinen LS, Cambell J, Canaves JM, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, ... ... Stevens RC, et al. Crystal structure of an allantoicase (YIR029W) from Saccharomyces cerevisiae at 2.4 A resolution. Proteins. 56: 619-24. PMID 15229895 DOI: 10.1002/Prot.20164 |
0.563 |
|
| 2004 |
McMullan D, Schwarzenbacher R, Jaroszewski L, von Delft F, Klock HE, Vincent J, Quijano K, Abdubek P, Ambing E, Biorac T, Brinen LS, Canaves JM, Dai X, Deacon AM, DiDonato M, ... ... Stevens RC, et al. Crystal structure of a novel Thermotoga maritima enzyme (TM1112) from the cupin family at 1.83 A resolution. Proteins. 56: 615-8. PMID 15229894 DOI: 10.1002/Prot.20139 |
0.545 |
|
| 2004 |
Jaroszewski L, Schwarzenbacher R, von Delft F, McMullan D, Brinen LS, Canaves JM, Dai X, Deacon AM, DiDonato M, Elsliger MA, Eshagi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, ... ... Stevens RC, et al. Crystal structure of a novel manganese-containing cupin (TM1459) from Thermotoga maritima at 1.65 A resolution. Proteins. 56: 611-4. PMID 15229893 DOI: 10.1002/Prot.20130 |
0.572 |
|
| 2004 |
Bakolitsa C, Schwarzenbacher R, McMullan D, Brinen LS, Canaves JM, Dai X, Deacon AM, Elsliger MA, Eshagi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, Jaroszewski L, Karlak C, ... ... Stevens RC, et al. Crystal structure of an orphan protein (TM0875) from Thermotoga maritima at 2.00-A resolution reveals a new fold. Proteins. 56: 607-10. PMID 15229892 DOI: 10.1002/Prot.20138 |
0.581 |
|
| 2004 |
Levin I, Schwarzenbacher R, Page R, Abdubek P, Ambing E, Biorac T, Brinen LS, Campbell J, Canaves JM, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, Floyd R, ... ... Stevens RC, et al. Crystal structure of a PIN (PilT N-terminus) domain (AF0591) from Archaeoglobus fulgidus at 1.90 A resolution. Proteins. 56: 404-8. PMID 15211526 DOI: 10.1002/Prot.20090 |
0.538 |
|
| 2004 |
Spraggon G, Schwarzenbacher R, Kreusch A, McMullan D, Brinen LS, Canaves JM, Dai X, Deacon AM, Elsliger MA, Eshagi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, Jaroszewski L, ... ... Stevens RC, et al. Crystal structure of a methionine aminopeptidase (TM1478) from Thermotoga maritima at 1.9 A resolution. Proteins. 56: 396-400. PMID 15211524 DOI: 10.1002/Prot.20084 |
0.565 |
|
| 2004 |
Schwarzenbacher R, von Delft F, Jaroszewski L, Abdubek P, Ambing E, Biorac T, Brinen LS, Canaves JM, Cambell J, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, Eshagi S, ... ... Stevens RC, et al. Crystal structure of a putative oxalate decarboxylase (TM1287) from Thermotoga maritima at 1.95 A resolution. Proteins. 56: 392-5. PMID 15211523 DOI: 10.1002/Prot.20016 |
0.565 |
|
| 2004 |
Heine A, Canaves JM, von Delft F, Brinen LS, Dai X, Deacon AM, Elsliger MA, Eshaghi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, Guda C, Jaroszewski L, Karlak C, ... ... Stevens RC, et al. Crystal structure of O-acetylserine sulfhydrylase (TM0665) from Thermotoga maritima at 1.8 A resolution. Proteins. 56: 387-91. PMID 15211522 DOI: 10.1002/Prot.20003 |
0.708 |
|
| 2004 |
Bracey MH, Cravatt BF, Stevens RC. Structural commonalities among integral membrane enzymes. Febs Letters. 567: 159-65. PMID 15178315 DOI: 10.1016/J.Febslet.2004.04.084 |
0.355 |
|
| 2004 |
Xu Q, Schwarzenbacher R, McMullan D, von Delft F, Brinen LS, Canaves JM, Dai X, Deacon AM, Elsliger MA, Eshagi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, Jaroszewski L, ... ... Stevens RC, et al. Crystal structure of a ribose-5-phosphate isomerase RpiB (TM1080) from Thermotoga maritima at 1.90 A resolution. Proteins. 56: 171-5. PMID 15162497 DOI: 10.1002/Prot.20129 |
0.565 |
|
| 2004 |
Santelli E, Schwarzenbacher R, McMullan D, Biorac T, Brinen LS, Canaves JM, Cambell J, Dai X, Deacon AM, Elsliger MA, Eshagi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, ... ... Stevens RC, et al. Crystal structure of a glycerophosphodiester phosphodiesterase (GDPD) from Thermotoga maritima (TM1621) at 1.60 A resolution. Proteins. 56: 167-70. PMID 15162496 DOI: 10.1002/Prot.20120 |
0.564 |
|
| 2004 |
Spraggon G, Schwarzenbacher R, Kreusch A, Lee CC, Abdubek P, Ambing E, Biorac T, Brinen LS, Canaves JM, Cambell J, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, ... ... Stevens RC, et al. Crystal structure of an Udp-n-acetylmuramate-alanine ligase MurC (TM0231) from Thermotoga maritima at 2.3 A resolution. Proteins. 55: 1078-81. PMID 15146505 DOI: 10.1002/Prot.20034 |
0.551 |
|
| 2004 |
Schwarzenbacher R, Jaroszewski L, von Delft F, Abdubek P, Ambing E, Biorac T, Brinen LS, Canaves JM, Cambell J, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, Eshagi S, ... ... Stevens RC, et al. Crystal structure of a type II quinolic acid phosphoribosyltransferase (TM1645) from Thermotoga maritima at 2.50 A resolution. Proteins. 55: 768-71. PMID 15103640 DOI: 10.1002/Prot.20029 |
0.537 |
|
| 2004 |
Schwarzenbacher R, Jaroszewski L, von Delft F, Abdubek P, Ambing E, Biorac T, Brinen LS, Canaves JM, Cambell J, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, Eshagi S, ... ... Stevens RC, et al. Crystal structure of an aspartate aminotransferase (TM1255) from Thermotoga maritima at 1.90 A resolution. Proteins. 55: 759-63. PMID 15103638 DOI: 10.1002/Prot.10646 |
0.565 |
|
| 2004 |
Schwarzenbacher R, Jaroszewski L, von Delft F, Abdubek P, Ambing E, Biorac T, Brinen LS, Canaves JM, Cambell J, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, Eshagi S, ... ... Stevens RC, et al. Crystal structure of a phosphoribosylaminoimidazole mutase PurE (TM0446) from Thermotoga maritima at 1.77-A resolution. Proteins. 55: 474-8. PMID 15048837 DOI: 10.1002/Prot.20023 |
0.564 |
|
| 2004 |
Stevens RC. Long live structural biology. Nature Structural & Molecular Biology. 11: 293-5. PMID 15048098 DOI: 10.1038/Nsmb0404-293 |
0.356 |
|
| 2004 |
Schwarzenbacher R, von Delft F, Abdubek P, Ambing E, Biorac T, Brinen LS, Canaves JM, Cambell J, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, Eshagi S, Floyd R, ... ... Stevens RC, et al. Crystal structure of a putative PII-like signaling protein (TM0021) from Thermotoga maritima at 2.5 A resolution. Proteins. 54: 810-3. PMID 14997579 DOI: 10.1002/Prot.10647 |
0.577 |
|
| 2004 |
Erlandsen H, Canaves JM, Elsliger MA, von Delft F, Brinen LS, Dai X, Deacon AM, Floyd R, Godzik A, Grittini C, Grzechnik SK, Jaroszewski L, Klock HE, Koesema E, Kovarik JS, ... ... Stevens RC, et al. Crystal structure of an HEPN domain protein (TM0613) from Thermotoga maritima at 1.75 A resolution. Proteins. 54: 806-9. PMID 14997578 DOI: 10.1002/Prot.10631 |
0.566 |
|
| 2004 |
Schwarzenbacher R, Deacon AM, Jaroszewski L, Brinen LS, Canaves JM, Dai X, Elsliger MA, Floyd R, Godzik A, Grittini C, Grzechnik SK, Klock HE, Koesema E, Kovarik JS, Kreusch A, ... ... Stevens RC, et al. Crystal structure of a putative glutamine amido transferase (TM1158) from Thermotoga maritima at 1.7 A resolution. Proteins. 54: 801-5. PMID 14997577 DOI: 10.1002/Prot.10614 |
0.568 |
|
| 2004 |
Pantazatos D, Kim JS, Klock HE, Stevens RC, Wilson IA, Lesley SA, Woods VL. Rapid refinement of crystallographic protein construct definition employing enhanced hydrogen/deuterium exchange MS. Proceedings of the National Academy of Sciences of the United States of America. 101: 751-6. PMID 14715906 DOI: 10.1073/Pnas.0307204101 |
0.368 |
|
| 2004 |
Schwarzenbacher R, von Delft F, Canaves JM, Brinen LS, Dai X, Deacon AM, Elsliger MA, Eshaghi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, Guda C, Jaroszewski L, Karlak C, ... ... Stevens RC, et al. Crystal structure of an iron-containing 1,3-propanediol dehydrogenase (TM0920) from Thermotoga maritima at 1.3 A resolution. Proteins. 54: 174-7. PMID 14705036 DOI: 10.1002/Prot.10594 |
0.707 |
|
| 2004 |
Page R, Nelson MS, von Delft F, Elsliger MA, Canaves JM, Brinen LS, Dai X, Deacon AM, Floyd R, Godzik A, Grittini C, Grzechnik SK, Jaroszewski L, Klock HE, Koesema E, ... ... Stevens RC, et al. Crystal structure of gamma-glutamyl phosphate reductase (TM0293) from Thermotoga maritima at 2.0 A resolution. Proteins. 54: 157-61. PMID 14705032 DOI: 10.1002/Prot.10562 |
0.555 |
|
| 2004 |
Hosfield D, Palan J, Hilgers M, Scheibe D, McRee DE, Stevens RC. A fully integrated protein crystallization platform for small-molecule drug discovery. Journal of Structural Biology. 142: 207-17. PMID 12718932 DOI: 10.1016/S1047-8477(03)00051-0 |
0.352 |
|
| 2004 |
Asmar GA, Hanson MA, Ward AB, Lasalde JA, Stevens RC, Potter C, Kuhn P. Low-Voltage Electron Microscopy (LVEM) as a probe for solubilized membrane protein aggregation states Microscopy and Microanalysis. 10: 1492-1493. DOI: 10.1017/S1431927604886069 |
0.503 |
|
| 2003 |
Weselak M, Patch MG, Selby TL, Knebel G, Stevens RC. Robotics for automated crystal formation and analysis. Methods in Enzymology. 368: 45-76. PMID 14674268 DOI: 10.1016/S0076-6879(03)68004-3 |
0.629 |
|
| 2003 |
Schwarzenbacher R, Canaves JM, Brinen LS, Dai X, Deacon AM, Elsliger MA, Eshaghi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, Guda C, Jaroszewski L, Karlak C, Klock HE, ... ... Stevens RC, et al. Crystal structure of uronate isomerase (TM0064) from Thermotoga maritima at 2.85 A resolution. Proteins. 53: 142-5. PMID 12945057 DOI: 10.1002/Prot.10462 |
0.664 |
|
| 2003 |
Yin J, Beuscher AE, Andryski SE, Stevens RC, Schultz PG. Structural plasticity and the evolution of antibody affinity and specificity. Journal of Molecular Biology. 330: 651-6. PMID 12850137 DOI: 10.1016/S0022-2836(03)00631-4 |
0.814 |
|
| 2003 |
Page R, Grzechnik SK, Canaves JM, Spraggon G, Kreusch A, Kuhn P, Stevens RC, Lesley SA. Shotgun crystallization strategy for structural genomics: an optimized two-tiered crystallization screen against the Thermotoga maritima proteome. Acta Crystallographica. Section D, Biological Crystallography. 59: 1028-37. PMID 12777766 DOI: 10.1107/S0907444903007790 |
0.548 |
|
| 2003 |
Yin J, Andryski SE, Beuscher AE, Stevens RC, Schultz PG. Structural evidence for substrate strain in antibody catalysis. Proceedings of the National Academy of Sciences of the United States of America. 100: 856-61. PMID 12552112 DOI: 10.1073/Pnas.0235873100 |
0.795 |
|
| 2003 |
Brinen LS, Canaves JM, Dai X, Deacon AM, Elsliger MA, Eshaghi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, Guda C, Jaroszewski L, Karlak C, Klock HE, Koesema E, ... ... Stevens RC, et al. Crystal structure of a zinc-containing glycerol dehydrogenase (TM0423) from Thermotoga maritima at 1.5 A resolution. Proteins. 50: 371-4. PMID 12486729 DOI: 10.1002/Prot.10302 |
0.664 |
|
| 2003 |
Kuhn P, Wilson K, Patch MG, Stevens RC. The genesis of high-throughput structure-based drug discovery using protein crystallography. Current Opinion in Chemical Biology. 6: 704-10. PMID 12413557 DOI: 10.1016/S1367-5931(02)00361-7 |
0.36 |
|
| 2002 |
Bracey MH, Hanson MA, Masuda KR, Stevens RC, Cravatt BF. Structural adaptations in a membrane enzyme that terminates endocannabinoid signaling. Science (New York, N.Y.). 298: 1793-6. PMID 12459591 DOI: 10.1126/Science.1076535 |
0.576 |
|
| 2002 |
Wang L, Erlandsen H, Haavik J, Knappskog PM, Stevens RC. Three-dimensional structure of human tryptophan hydroxylase and its implications for the biosynthesis of the neurotransmitters serotonin and melatonin. Biochemistry. 41: 12569-74. PMID 12379098 DOI: 10.1021/Bi026561F |
0.36 |
|
| 2002 |
Kuhn P, Lesley SA, Mathews II, Canaves JM, Brinen LS, Dai X, Deacon AM, Elsliger MA, Eshaghi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, Guda C, Hodgson KO, ... ... Stevens RC, et al. Crystal structure of thy1, a thymidylate synthase complementing protein from Thermotoga maritima at 2.25 A resolution. Proteins. 49: 142-5. PMID 12211025 DOI: 10.1002/Prot.10202 |
0.673 |
|
| 2002 |
Lesley SA, Kuhn P, Godzik A, Deacon AM, Mathews I, Kreusch A, Spraggon G, Klock HE, McMullan D, Shin T, Vincent J, Robb A, Brinen LS, Miller MD, McPhillips TM, ... ... Stevens RC, et al. Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline. Proceedings of the National Academy of Sciences of the United States of America. 99: 11664-9. PMID 12193646 DOI: 10.1073/Pnas.142413399 |
0.704 |
|
| 2002 |
Erlandsen H, Kim JY, Patch MG, Han A, Volner A, Abu-Omar MM, Stevens RC. Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates. Journal of Molecular Biology. 320: 645-61. PMID 12096915 DOI: 10.1016/S0022-2836(02)00496-5 |
0.372 |
|
| 2002 |
Song J, Cheng Q, Stevens RC. Morphological manipulation of bolaamphiphilic polydiacetylene assemblies by controlled lipid doping. Chemistry and Physics of Lipids. 114: 203-14. PMID 11934401 DOI: 10.1016/S0009-3084(02)00007-5 |
0.589 |
|
| 2002 |
Santarsiero BD, Yegian DT, Lee CC, Spraggon G, Gu J, Scheibe D, Uber DC, Cornell EW, Nordmeyer RA, Kolbe WF, Jin J, Jones AL, Jaklevic JM, Schultz PG, Stevens RC. An approach to rapid protein crystallization using nanodroplets Journal of Applied Crystallography. 35: 278-281. DOI: 10.1107/S0021889802001474 |
0.737 |
|
| 2002 |
Song J, Cheng Q, Zhu S, Stevens RC. Biomedical Microdevices. 4: 213-221. DOI: 10.1023/A:1016000530783 |
0.588 |
|
| 2001 |
Yin J, Mundorff EC, Yang PL, Wendt KU, Hanway D, Stevens RC, Schultz PG. A comparative analysis of the immunological evolution of antibody 28B4. Biochemistry. 40: 10764-73. PMID 11535051 DOI: 10.1021/Bi010536C |
0.794 |
|
| 2001 |
Stevens RC, Wilson IA. Tech.Sight. Industrializing structural biology. Science (New York, N.Y.). 293: 519-20. PMID 11463918 DOI: 10.1126/Science.293.5529.519 |
0.38 |
|
| 2001 |
Song J, Cheng Q, Kopta S, Stevens RC. Modulating artificial membrane morphology: pH-induced chromatic transition and nanostructural transformation of a bolaamphiphilic conjugated polymer from blue helical ribbons to red nanofibers. Journal of the American Chemical Society. 123: 3205-13. PMID 11457054 DOI: 10.1021/Ja0035046 |
0.564 |
|
| 2001 |
Rossetto O, Caccin P, Rigoni M, Tonello F, Bortoletto N, Stevens RC, Montecucco C. Active-site mutagenesis of tetanus neurotoxin implicates TYR-375 and GLU-271 in metalloproteolytic activity. Toxicon : Official Journal of the International Society On Toxinology. 39: 1151-9. PMID 11306125 DOI: 10.1016/S0041-0101(00)00252-X |
0.33 |
|
| 2001 |
Chen DW, Beuscher AE, Stevens RC, Wirsching P, Lerner RA, Janda KD. Preparation of stilbene-tethered nonnatural nucleosides for use with blue-fluorescent antibodies. The Journal of Organic Chemistry. 66: 1725-32. PMID 11262119 DOI: 10.1021/Jo001676F |
0.787 |
|
| 2001 |
Orencia MC, Yoon JS, Ness JE, Stemmer WP, Stevens RC. Predicting the emergence of antibiotic resistance by directed evolution and structural analysis. Nature Structural Biology. 8: 238-42. PMID 11224569 DOI: 10.1038/84981 |
0.781 |
|
| 2001 |
Baek MG, Stevens RC, Charych DH. Design and synthesis of novel glycopolythiophene assemblies for colorimetric detection of influenza virus and E. coli. Bioconjugate Chemistry. 11: 777-88. PMID 11087325 DOI: 10.1021/Bc000026F |
0.349 |
|
| 2001 |
Stevens R, Hanson M. Nature Structural Biology. 8: 664-664. DOI: 10.1038/90364 |
0.52 |
|
| 2000 |
Rogers JP, Luginbühl P, Pemberton K, Harty P, Wemmer DE, Stevens RC. Structure-activity relationships in a peptidic alpha7 nicotinic acetylcholine receptor antagonist. Journal of Molecular Biology. 304: 911-26. PMID 11124036 DOI: 10.1006/Jmbi.2000.4247 |
0.718 |
|
| 2000 |
Erlandsen H, Abola EE, Stevens RC. Combining structural genomics and enzymology: completing the picture in metabolic pathways and enzyme active sites. Current Opinion in Structural Biology. 10: 719-30. PMID 11114510 DOI: 10.1016/S0959-440X(00)00154-8 |
0.363 |
|
| 2000 |
Abola E, Kuhn P, Earnest T, Stevens RC. Automation of X-ray crystallography. Nature Structural Biology. 973-7. PMID 11104004 DOI: 10.1038/80754 |
0.347 |
|
| 2000 |
Orencia MC, Hanson MA, Stevens RC. Structural analysis of affinity matured antibodies and laboratory-evolved enzymes. Advances in Protein Chemistry. 55: 227-59. PMID 11050935 DOI: 10.1016/S0065-3233(01)55005-6 |
0.805 |
|
| 2000 |
Stevens RC. High-throughput protein crystallization. Current Opinion in Structural Biology. 10: 558-63. PMID 11042454 DOI: 10.1016/S0959-440X(00)00131-7 |
0.302 |
|
| 2000 |
Simeonov A, Matsushita M, Juban EA, Thompson EH, Hoffman TZ, Beuscher AE, Taylor MJ, Wirsching P, Rettig W, McCusker JK, Stevens RC, Millar DP, Schultz PG, Lerner RA, Janda KD. Blue-fluorescent antibodies. Science (New York, N.Y.). 290: 307-13. PMID 11030644 DOI: 10.1126/Science.290.5490.307 |
0.778 |
|
| 2000 |
Hanson MA, Stevens RC. Cocrystal structure of synaptobrevin-II bound to botulinum neurotoxin type B at 2.0 A resolution. Nature Structural Biology. 7: 687-92. PMID 10932255 DOI: 10.1038/77997 |
0.568 |
|
| 2000 |
Peng T, Cheng Q, Stevens RC. Amperometric detection of Escherichia coli heat-labile enterotoxin by redox diacetylenic vesicles on a sol-gel thin-film electrode. Analytical Chemistry. 72: 1611-1617. PMID 10763260 DOI: 10.1021/Ac990406Y |
0.469 |
|
| 2000 |
Erlandsen H, Bjørgo E, Flatmark T, Stevens RC. Crystal structure and site-specific mutagenesis of pterin-bound human phenylalanine hydroxylase. Biochemistry. 39: 2208-17. PMID 10694386 DOI: 10.1021/Bi992531+ |
0.362 |
|
| 2000 |
Mundorff EC, Hanson MA, Varvak A, Ulrich H, Schultz PG, Stevens RC. Conformational effects in biological catalysis: an antibody-catalyzed oxy-cope rearrangement. Biochemistry. 39: 627-32. PMID 10651626 DOI: 10.1021/Bi9924314 |
0.808 |
|
| 2000 |
Cheng Q, Yamamoto M, Stevens RC. Amino Acid Terminated Polydiacetylene Lipid Microstructures: Morphology and Chromatic Transition Langmuir. 16: 5333-5342. DOI: 10.1021/La9916169 |
0.5 |
|
| 2000 |
Hanson MA, Oost TK, Sukonpan C, Rich DH, Stevens RC. Structural basis for BABIM inhibition of botulinum neurotoxin type B protease [22] Journal of the American Chemical Society. 122: 11268-11269. DOI: 10.1021/Ja005533M |
0.532 |
|
| 1999 |
Spiller B, Gershenson A, Arnold FH, Stevens RC. A structural view of evolutionary divergence. Proceedings of the National Academy of Sciences of the United States of America. 96: 12305-10. PMID 10535917 DOI: 10.1073/Pnas.96.22.12305 |
0.687 |
|
| 1999 |
Lacy DB, Stevens RC. Sequence homology and structural analysis of the clostridial neurotoxins. Journal of Molecular Biology. 291: 1091-104. PMID 10518945 DOI: 10.1006/Jmbi.1999.2945 |
0.593 |
|
| 1999 |
Kobe B, Jennings IG, House CM, Michell BJ, Goodwill KE, Santarsiero BD, Stevens RC, Cotton RG, Kemp BE. Structural basis of autoregulation of phenylalanine hydroxylase. Nature Structural Biology. 6: 442-8. PMID 10331871 DOI: 10.1038/8247 |
0.703 |
|
| 1999 |
Rogers JP, Luginbühl P, Shen GS, McCabe RT, Stevens RC, Wemmer DE. NMR solution structure of alpha-conotoxin ImI and comparison to other conotoxins specific for neuronal nicotinic acetylcholine receptors. Biochemistry. 38: 3874-82. PMID 10194298 DOI: 10.1021/bi9826254 |
0.684 |
|
| 1999 |
Cheng Q, Peng T, Stevens RC. Signaling ofEscherichia ColiEnterotoxin on Supramolecular Redox Bilayer Vesicles Journal of the American Chemical Society. 121: 6767-6768. DOI: 10.1021/Ja991234P |
0.52 |
|
| 1999 |
Cheng Q, Fu JA, Burkard R, Wang W, Yamamoto M, Yang J, Stevens RC. Monolayer and epi-fluorescence microscopy studies of amino acid derivatized diacetylene lipids Thin Solid Films. 345: 292-299. DOI: 10.1016/S0040-6090(98)01608-3 |
0.479 |
|
| 1998 |
Lacy DB, Stevens RC. Unraveling the structures and modes of action of bacterial toxins. Current Opinion in Structural Biology. 8: 778-84. PMID 9914258 DOI: 10.1016/S0959-440X(98)80098-5 |
0.584 |
|
| 1998 |
Erlandsen H, Flatmark T, Stevens RC, Hough E. Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 A resolution. Biochemistry. 37: 15638-46. PMID 9843368 DOI: 10.1021/Bi9815290 |
0.41 |
|
| 1998 |
Bjørgo E, Knappskog PM, Martinez A, Stevens RC, Flatmark T. Partial characterization and three-dimensional-structural localization of eight mutations in exon 7 of the human phenylalanine hydroxylase gene associated with phenylketonuria Febs Journal. 257: 1-10. PMID 9799096 DOI: 10.1046/J.1432-1327.1998.2570001.X |
0.332 |
|
| 1998 |
Lacy DB, Tepp W, Cohen AC, DasGupta BR, Stevens RC. Crystal structure of botulinum neurotoxin type A and implications for toxicity. Nature Structural Biology. 5: 898-902. PMID 9783750 DOI: 10.1038/2338 |
0.588 |
|
| 1998 |
Romesberg FE, Santarsiero BD, Spiller B, Yin J, Barnes D, Schultz PG, Stevens RC. Structural and kinetic evidence for strain in biological catalysis. Biochemistry. 37: 14404-9. PMID 9772166 DOI: 10.1021/Bi981578C |
0.775 |
|
| 1998 |
Goodwill KE, Sabatier C, Stevens RC. Crystal structure of tyrosine hydroxylase with bound cofactor analogue and iron at 2.3 A resolution: self-hydroxylation of Phe300 and the pterin-binding site. Biochemistry. 37: 13437-45. PMID 9753429 DOI: 10.1021/Bi981462G |
0.318 |
|
| 1998 |
Kim CU, Lew W, Williams MA, Wu H, Zhang L, Chen X, Escarpe PA, Mendel DB, Laver WG, Stevens RC. Structure-activity relationship studies of novel carbocyclic influenza neuraminidase inhibitors. Journal of Medicinal Chemistry. 41: 2451-60. PMID 9651151 DOI: 10.1021/Jm980162U |
0.301 |
|
| 1998 |
Fusetti F, Erlandsen H, Flatmark T, Stevens RC. Structure of tetrameric human phenylalanine hydroxylase and its implications for phenylketonuria. The Journal of Biological Chemistry. 273: 16962-7. PMID 9642259 DOI: 10.1074/Jbc.273.27.16962 |
0.37 |
|
| 1998 |
Andersen B, Stevens RC. The human D1A dopamine receptor: heterologous expression in Saccharomyces cerevisiae and purification of the functional receptor. Protein Expression and Purification. 13: 111-9. PMID 9631523 DOI: 10.1006/Prep.1998.0862 |
0.392 |
|
| 1998 |
Romesberg FE, Spiller B, Schultz PG, Stevens RC. Immunological origins of binding and catalysis in a Diels-Alderase antibody. Science (New York, N.Y.). 279: 1929-33. PMID 9506942 DOI: 10.1126/Science.279.5358.1929 |
0.738 |
|
| 1998 |
Lagow RJ, Kampa JJ, Wei H, Battle SL, Genge JW, Laude DA, Harper CJ, Mitchell DR, Bau R, Stevens RC, Haw JF, Munson E. Synthesis of Linear Acetylenic Carbon Tanso. 1998: 27-33. DOI: 10.7209/Tanso.1998.27 |
0.572 |
|
| 1998 |
Lagow RJ, Kampa JJ, Wei H, Battle SL, Genge JW, Laude DA, Harper CJ, Mitchell DR, Bau R, Stevens RC, Haw JF, Munson E. Synthesis of linear acetylenic carbon; The fourth carbon allotrope Carbon. 36: 1248. DOI: 10.1016/S0008-6223(98)80015-8 |
0.551 |
|
| 1997 |
Kim CU, Lew W, Williams MA, Liu H, Zhang L, Swaminathan S, Bischofberger N, Chen MS, Mendel DB, Tai CY, Laver WG, Stevens RC. Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: design, synthesis, and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity. Journal of the American Chemical Society. 119: 681-90. PMID 16526129 DOI: 10.1021/Ja963036T |
0.304 |
|
| 1997 |
Erlandsen H, Fusetti F, Martinez A, Hough E, Flatmark T, Stevens RC. Crystal structure of the catalytic domain of human phenylalanine hydroxylase reveals the structural basis for phenylketonuria. Nature Structural Biology. 4: 995-1000. PMID 9406548 DOI: 10.1038/Nsb1297-995 |
0.392 |
|
| 1997 |
Lacy DB, Stevens RC. Recombinant expression and purification of the botulinum neurotoxin type A translocation domain. Protein Expression and Purification. 11: 195-200. PMID 9367816 DOI: 10.1006/Prep.1997.0772 |
0.549 |
|
| 1997 |
Burkard F, Chen F, Kuziemko GM, Stevens RC. Electron density projection map of the botulinum neurotoxin 900-kilodalton complex by electron crystallography. Journal of Structural Biology. 120: 78-84. PMID 9356295 DOI: 10.1006/Jsbi.1997.3910 |
0.329 |
|
| 1997 |
Ulrich HD, Mundorff E, Santarsiero BD, Driggers EM, Stevens RC, Schultz PG. The interplay between binding energy and catalysis in the evolution of a catalytic antibody. Nature. 389: 271-5. PMID 9305839 DOI: 10.1038/38470 |
0.729 |
|
| 1997 |
Goodwill KE, Sabatier C, Marks C, Raag R, Fitzpatrick PF, Stevens RC. Crystal structure of tyrosine hydroxylase at 2.3 A and its implications for inherited neurodegenerative diseases. Nature Structural Biology. 4: 578-85. PMID 9228951 DOI: 10.1038/Nsb0797-578 |
0.368 |
|
| 1997 |
David NE, Gee M, Andersen B, Naider F, Thorner J, Stevens RC. Expression and purification of the Saccharomyces cerevisiae alpha-factor receptor (Ste2p), a 7-transmembrane-segment G protein-coupled receptor. The Journal of Biological Chemistry. 272: 15553-61. PMID 9182592 DOI: 10.1074/Jbc.272.24.15553 |
0.81 |
|
| 1997 |
Wedemayer GJ, Patten PA, Wang LH, Schultz PG, Stevens RC. Structural insights into the evolution of an antibody combining site. Science (New York, N.Y.). 276: 1665-9. PMID 9180069 DOI: 10.1126/Science.276.5319.1665 |
0.513 |
|
| 1997 |
Wedemayer GJ, Wang LH, Patten PA, Schultz PG, Stevens RC. Crystal structures of the free and liganded form of an esterolytic catalytic antibody. Journal of Molecular Biology. 268: 390-400. PMID 9159478 DOI: 10.1006/Jmbi.1997.0974 |
0.554 |
|
| 1997 |
Charych D, Cheng Q, Reichert A, Kuziemko G, Stroh M, Nagy JO, Spevak W, Stevens RC. A 'litmus test' for molecular recognition using artificial membranes. Chemistry & Biology. 3: 113-20. PMID 8807836 DOI: 10.1016/S1074-5521(96)90287-2 |
0.501 |
|
| 1997 |
Cheng Q, Stevens RC. Monolayer properties of monosialioganglioside in the mixed diacetylene lipid films on the air/water interface Chemistry and Physics of Lipids. 87: 41-53. DOI: 10.1016/S0009-3084(97)00022-4 |
0.469 |
|
| 1997 |
Cheng Q, Stevens RC. Coupling of an induced fit enzyme to polydiacetylene thin films: Colorimetric detection of glucose Advanced Materials. 9: 481-483. DOI: 10.1002/Adma.19970090605 |
0.447 |
|
| 1996 |
Hsieh-Wilson LC, Schultz PG, Stevens RC. Insights into antibody catalysis: structure of an oxygenation catalyst at 1.9-angstrom resolution. Proceedings of the National Academy of Sciences of the United States of America. 93: 5363-7. PMID 8643580 DOI: 10.1073/Pnas.93.11.5363 |
0.51 |
|
| 1996 |
Kuziemko GM, Stroh M, Stevens RC. Cholera toxin binding affinity and specificity for gangliosides determined by surface plasmon resonance. Biochemistry. 35: 6375-84. PMID 8639583 DOI: 10.1021/Bi952314I |
0.301 |
|
| 1996 |
Patten PA, Gray NS, Yang PL, Marks CB, Wedemayer GJ, Boniface JJ, Stevens RC, Schultz PG. The immunological evolution of catalysis. Science (New York, N.Y.). 271: 1086-91. PMID 8599084 DOI: 10.1126/Science.271.5252.1086 |
0.513 |
|
| 1996 |
Santarsiero BD, Hsieh-Wilson LC, Schultz PG, Stevens RC. A sulfide oxidation catalytic antibody Acta Crystallographica Section a Foundations of Crystallography. 52: C223-C224. DOI: 10.1107/S0108767396090435 |
0.678 |
|
| 1996 |
Spiller B, Santarsiero BD, Hsieh L, Stevens R. Crystal structure of an amino-acylation catalytic antibody Acta Crystallographica Section a Foundations of Crystallography. 52: C224-C224. DOI: 10.1107/S010876739609040X |
0.704 |
|
| 1996 |
Goodwill KE, Granlund E, Santarsiero BD, Stevens RC. Design of an inverted spindle axis for frozen crystal screening and storage Journal of Applied Crystallography. 29: 738-740. DOI: 10.1107/S0021889896006188 |
0.678 |
|
| 1996 |
Stevens RC, Hsieh-Wilson LC, Santarsiero BD, Wedemayer GJ, Spiller B, Wang LH, Barnes D, Ulrich HD, Patten PA, Romesberg FE, Schultz PG. Structural Studies of Catalytic Antibodies Israel Journal of Chemistry. 36: 121-132. DOI: 10.1002/Ijch.199600018 |
0.725 |
|
| 1995 |
Lagow RJ, Kampa JJ, Wei HC, Battle SL, Genge JW, Laude DA, Harper CJ, Bau R, Stevens RC, Haw JF, Munson E. Synthesis of Linear Acetylenic Carbon: The "sp" Carbon Allotrope. Science (New York, N.Y.). 267: 362-7. PMID 17837484 DOI: 10.1126/Science.267.5196.362 |
0.571 |
|
| 1994 |
Yuan HS, Stevens RC, Bau R, Mosher HS, Koetzle TF. Determination of the absolute configuration of (+)-neopentyl-1-d alcohol by neutron and x-ray diffraction analysis. Proceedings of the National Academy of Sciences of the United States of America. 91: 12872-6. PMID 7809138 DOI: 10.1073/Pnas.91.26.12872 |
0.765 |
|
| 1992 |
Stevens RC, Lipscomb WN. A molecular mechanism for pyrimidine and purine nucleotide control of aspartate transcarbamoylase. Proceedings of the National Academy of Sciences of the United States of America. 89: 5281-5. PMID 1608935 DOI: 10.1073/Pnas.89.12.5281 |
0.565 |
|
| 1992 |
Newton CJ, Stevens RC, Kantrowitz ER. Importance of a conserved residue, aspartate-162, for the function of Escherichia coli aspartate transcarbamoylase Biochemistry®. 31: 3026-3032. PMID 1550826 DOI: 10.1021/Bi00126A026 |
0.57 |
|
| 1992 |
Stebbins JW, Robertson DE, Roberts MF, Stevens RC, Lipscomb WN, Kantrowitz ER. Arginine 54 in the active site of Escherichia coli aspartate transcarbamoylase is critical for catalysis: a site-specific mutagenesis, NMR, and X-ray crystallographic study. Protein Science : a Publication of the Protein Society. 1: 1435-46. PMID 1303763 DOI: 10.1002/Pro.5560011105 |
0.715 |
|
| 1991 |
Stevens RC, Reinisch KM, Lipscomb WN. Molecular structure of Bacillus subtilis aspartate transcarbamoylase at 3.0 A resolution. Proceedings of the National Academy of Sciences of the United States of America. 88: 6087-91. PMID 1906175 DOI: 10.1073/Pnas.88.14.6087 |
0.597 |
|
| 1991 |
Stevens RC, Chook YM, Cho CY, Lipscomb WN, Kantrowitz ER. Escherichia coli aspartate carbamoyltransferase: the probing of crystal structure analysis via site-specific mutagenesis. Protein Engineering. 4: 391-408. PMID 1881865 DOI: 10.1093/Protein/4.4.391 |
0.814 |
|
| 1991 |
Stevens RC, Evenson ML, Tepp W, DasGupta BR. Crystallization and preliminary X-ray analysis of botulinum neurotoxin type A. Journal of Molecular Biology. 222: 877-80. PMID 1762156 DOI: 10.1016/0022-2836(91)90581-P |
0.306 |
|
| 1991 |
Stevens RC, Ricci JS, Koetzle TF, Herrmann WA. Transition metal methylene complexes. LXVII. Neutron diffraction study of μ-propylidene(2)-bis[carbonyl(η5-pentamethylcyclopentadienyl)rhodium-(RhRh)], [μ-C(CH3)2][{η5-C5(CH3)5}Rh(CO)]2, at 20 K Journal of Organometallic Chemistry. 412: 425-434. DOI: 10.1016/0022-328X(91)86087-7 |
0.625 |
|
| 1990 |
Gouaux JE, Stevens RC, Lipscomb WN. Crystal structures of aspartate carbamoyltransferase ligated with phosphonoacetamide, malonate, and CTP or ATP at 2.8-A resolution and neutral pH. Biochemistry. 29: 7702-15. PMID 2271529 DOI: 10.1021/Bi00485A020 |
0.797 |
|
| 1990 |
Stevens RC, Gouaux JE, Lipscomb WN. Structural consequences of effector binding to the T state of aspartate carbamoyltransferase: crystal structures of the unligated and ATP- and CTP-complexed enzymes at 2.6-A resolution. Biochemistry. 29: 7691-701. PMID 2271528 DOI: 10.1021/Bi00485A019 |
0.821 |
|
| 1990 |
Stevens RC, Lipscomb WN. Allosteric control of quaternary states in E. coli aspartate transcarbamylase. Biochemical and Biophysical Research Communications. 171: 1312-8. PMID 2222446 DOI: 10.1016/0006-291X(90)90829-C |
0.568 |
|
| 1990 |
Stevens RC, Bau R, Milstein D, Blum O, Koetzle TF. Concept of the H(δ+) ⋯ H(δ-) interaction. A low-temperature neutron diffraction study of cis-[IrH(OH)(PMe3)4]PF6 Journal of the Chemical Society, Dalton Transactions. 1429-1432. DOI: 10.1039/Dt9900001429 |
0.711 |
|
| 1990 |
Stevens RC, Bau R, Cramer RE, Afzal D, Gilje JW, Koetzle TF. Multiple-bond character in Cp3U:CHPMe3: first low-temperature neutron diffraction analysis of a uranium organometallic complex Organometallics. 9: 694-697. DOI: 10.1021/Om00117A026 |
0.675 |
|
| 1990 |
Stevens RC, Gouaux JE, Lipscomb WN. Structural consequences of effector binding to the T state of aspartate carbamoyltransferase: crystal structures of the unligated and ATP- and CTP-complexed enzymes at 2.6-.ANG. resolution [Erratum to document cited in CA113(11):93943z] Biochemistry. 29: 11146-11146. DOI: 10.1021/Bi00502A021 |
0.626 |
|
| 1990 |
Doxsee KM, Stevens RC. Complexation-mediated crystallization. Crystallization of sodium acetate trihydrate needles from cyclohexane solution Journal of Inclusion Phenomena and Molecular Recognition in Chemistry. 9: 327-336. DOI: 10.1007/Bf01033312 |
0.3 |
|
| 1990 |
MCLEAN MR, STEVENS RC, BAU R, KOETZLE TF. ChemInform Abstract: Location of the Elusive Hydride Ligand in HRh(P(C6H5)3)4 via a Neutron Diffraction Analysis. Cheminform. 21. DOI: 10.1002/chin.199018058 |
0.664 |
|
| 1989 |
Gouaux JE, Stevens RC, Ke HM, Lipscomb WN. Crystal structure of the Glu-239----Gln mutant of aspartate carbamoyltransferase at 3.1-A resolution: an intermediate quaternary structure. Proceedings of the National Academy of Sciences of the United States of America. 86: 8212-6. PMID 2573062 DOI: 10.1073/Pnas.86.21.8212 |
0.798 |
|
| 1989 |
Stevens RC, McLean MR, Bau R, Koetzle TF. Neutron diffraction structure analysis of a hexanuclear copper hydrido complex, H6Cu6[P(p-tolyl)3]6: an unexpected finding Journal of the American Chemical Society. 111: 3472-3473. DOI: 10.1021/Ja00191A077 |
0.678 |
|
| 1989 |
Stevens RC, Mclean MR, Wen T, Carpenter JD, Bau R, Koetzle TF. An X-ray and neutron diffraction structure analysis of a triply-bridged binuclear iridium complex, [[(C5(CH3)5Ir)2(μ-H)3]+ [ClO4]-• 2C6H6] Inorganica Chimica Acta. 161: 223-231. DOI: 10.1016/S0020-1693(00)83097-2 |
0.702 |
|
| 1989 |
McLean MR, Stevens RC, Bau R, Koetzle TF. Location of the elusive hydride ligand in HRh [P(C6H5)3]4 via a neutron diffraction analysis Inorganica Chimica Acta. 166: 173-175. DOI: 10.1016/S0020-1693(00)80807-5 |
0.688 |
|
| 1989 |
STEVENS RC, MCLEAN MR, BAU R, KOETZLE TF. ChemInform Abstract: Neutron Diffraction Structure Analysis of a Hexanuclear Copper Hydrido Complex, H6Cu6(P(p-tolyl)3)6: An Unexpected Finding. Cheminform. 20. DOI: 10.1002/chin.198932054 |
0.668 |
|
| 1988 |
Yuan HS, Stevens RC, Fujita S, Watkins MI, Koetzle TF, Bau R. Determination of the absolute configuration of (-)-(2R)-succinic-2-d acid by neutron diffraction study: unambiguous proof of the absolute stereochemistry of the NAD+/NADH interconversion. Proceedings of the National Academy of Sciences of the United States of America. 85: 2889-93. PMID 3362854 DOI: 10.1073/Pnas.85.9.2889 |
0.774 |
|
| 1988 |
Choi HK, Terzis A, Stevens RC, Bau R, Haugwitz R, Narayanan VL, Wolpert-DeFilippes M. Reaction products of a new anti-cancer agent, Pt(IV)(cyclohexyldiamine)Cl4, with guanosine and 9-methylguanine: first crystal structures of Pt(cyclohexyldiamine) complexes with a nucleobase and a nucleoside. Biochemical and Biophysical Research Communications. 156: 1120-4. PMID 3190689 DOI: 10.1016/S0006-291X(88)80748-4 |
0.596 |
|
| 1988 |
Bau R, Stevens RC, McLean M, Koetzle TF. Neutron Diffraction Analysis of HRh[P(C6H5)3]4 Materials Science Forum. 77-80. DOI: 10.4028/Www.Scientific.Net/Msf.27-28.77 |
0.571 |
|
| 1988 |
Olah GA, Farooq O, Farnia SMF, Bruce MR, Clouet FL, Morton PR, Prakash GKS, Stevens RC, Bau R, et al. .. Aluminum dichloride and dibromide. Preparation, spectroscopic (including matrix isolation) study, reactions, and role (together with alkyl(aryl)aluminum monohalides) in the preparation of organoaluminum compounds Journal of the American Chemical Society. 110: 3231-3238. DOI: 10.1021/Ja00218A037 |
0.611 |
|
| 1988 |
OLAH GA, FAROOQ O, FARNIA SMF, BRUCE MR, CLOUET FL, MORTON PR, PRAKASH GKS, STEVENS RC, BAU R, LAMMERTSMA K, SUZER S, ANDREWS L. ChemInform Abstract: Aluminum Dichloride and Dibromide. Preparation, Spectroscopic (Including Matrix Isolation) Study, Reactions, and Role (Together with Alkyl(aryl)aluminum Monohalides) in the Preparation of Organoaluminum Compounds. Cheminform. 19. DOI: 10.1002/chin.198836280 |
0.525 |
|
| 1987 |
Bau R, Stevens RC, McLean M, Koetzle TF. The neutron diffraction analysis of [(C5Me5)Ir(μ-H)3Ir(C5Me5)]+[ClO4]−·C6H6 Acta Crystallographica Section a Foundations of Crystallography. 43: C176-C176. DOI: 10.1107/S0108767387080735 |
0.675 |
|
| 1987 |
Prakash GKS, Keyaniyan S, Aniszfeld R, Heiliger L, Olah GA, Stevens RC, Choi HK, Bau R. Organometallic chemistry. 22. Triphenylsilyl perchlorate revisited: silicon-29 and chlorine-35 NMR spectroscopy and x-ray crystallography showing covalent nature in both solution and the solid state. Difficulties in observing long-lived silyl cations in the condensed state Journal of the American Chemical Society. 109: 5123-5126. DOI: 10.1021/Ja00251A013 |
0.638 |
|
| 1987 |
PRAKASH GKS, KEYANIYAN S, ANISZFELD R, HEILIGER L, OLAH GA, STEVENS RC, CHOI H, BAU R. ChemInform Abstract: Organometallic Chemistry. Part 22. Triphenylsilyl Perchlorate Revisited: 29Si and 35Cl NMR Spectroscopy and X-Ray Crystallography Showing Covalent Nature in Both Solution and the Solid State. Difficulties in Observing Long-Lived Silyl Cheminform. 18. DOI: 10.1002/chin.198749064 |
0.602 |
|
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