| Year |
Citation |
Score |
| 2023 |
Stazi G, Taglieri L, Nicolai A, Romanelli A, Fioravanti R, Morrone S, Sabatino M, Ragno R, Taurone S, Nebbioso M, Carletti R, Artico M, Valente S, Scarpa S, Mai A. Retraction Note: Dissecting the role of novel EZH2 inhibitors in primary glioblastoma cell cultures: effects on proliferation, epithelialmesenchymal transition, migration, and on the pro-inflammatory phenotype. Clinical Epigenetics. 15: 179. PMID 37936214 DOI: 10.1186/s13148-023-01595-6 |
0.538 |
|
| 2023 |
Schiavone V, Romasco T, Di Pietrantonio N, Garzoli S, Palmerini C, Di Tomo P, Pipino C, Mandatori D, Fioravanti R, Butturini E, Sabatino M, Baldassarre MPA, Ragno R, Pandolfi A, Di Pietro N. Essential Oils from Mediterranean Plants Inhibit In Vitro Monocyte Adhesion to Endothelial Cells from Umbilical Cords of Females with Gestational Diabetes Mellitus. International Journal of Molecular Sciences. 24. PMID 37108387 DOI: 10.3390/ijms24087225 |
0.554 |
|
| 2022 |
Proia E, Ragno A, Antonini L, Sabatino M, Mladenovič M, Capobianco R, Ragno R. Ligand-based and structure-based studies to develop predictive models for SARS-CoV-2 main protease inhibitors through the 3d-qsar.com portal. Journal of Computer-Aided Molecular Design. PMID 35716228 DOI: 10.1007/s10822-022-00460-7 |
0.661 |
|
| 2022 |
Artini M, Papa R, Sapienza F, Božović M, Vrenna G, Tuccio Guarna Assanti V, Sabatino M, Garzoli S, Fiscarelli EV, Ragno R, Selan L. Essential Oils Biofilm Modulation Activity and Machine Learning Analysis on Isolates from Cystic Fibrosis Patients. Microorganisms. 10. PMID 35630332 DOI: 10.3390/microorganisms10050887 |
0.543 |
|
| 2022 |
Kurtanović N, Tomašević N, Matić S, Proia E, Sabatino M, Antonini L, Mladenović M, Ragno R. Human Estrogen Receptor Alpha Antagonists, Part 3: 3-D Pharmacophore and 3-D QSAR Guided Brefeldin A Hit-to-Lead Optimization toward New Breast Cancer Suppressants. Molecules (Basel, Switzerland). 27. PMID 35566172 DOI: 10.3390/molecules27092823 |
0.607 |
|
| 2022 |
Taglienti A, Donati L, Ferretti L, Tomassoli L, Sapienza F, Sabatino M, Di Massimo G, Fiorentino S, Vecchiarelli V, Nota P, Ragno R. Antiphytoviral Activity of Essential Oils and Hydrosols From , , and to Control Zucchini Yellow Mosaic Virus and Tomato Leaf Curl New Delhi Virus in L. Frontiers in Microbiology. 13: 840893. PMID 35547120 DOI: 10.3389/fmicb.2022.840893 |
0.544 |
|
| 2022 |
Valentini E, D'Aguanno S, Di Martile M, Montesano C, Ferraresi V, Patsilinakos A, Sabatino M, Antonini L, Chiacchiarini M, Valente S, Mai A, Colotti G, Ragno R, Trisciuoglio D, Del Bufalo D. Targeting the anti-apoptotic Bcl-2 family proteins: machine learning virtual screening and biological evaluation of new small molecules. Theranostics. 12: 2427-2444. PMID 35265218 DOI: 10.7150/thno.64233 |
0.78 |
|
| 2021 |
Nowak RP, Tumber A, Hendrix E, Ansari MSZ, Sabatino M, Antonini L, Andrijes R, Salah E, Mautone N, Pellegrini FR, Simelis K, Kawamura A, Johansson C, Passeri D, Pellicciari R, ... ... Ragno R, et al. First-in-Class Inhibitors of the Ribosomal Oxygenase MINA53. Journal of Medicinal Chemistry. 64: 17031-17050. PMID 34843649 DOI: 10.1021/acs.jmedchem.1c00605 |
0.621 |
|
| 2021 |
Paglia G, Antonini L, Cervoni L, Ragno R, Sabatino M, Minacori M, Rubini E, Altieri F. A Comparative Analysis of Punicalagin Interaction with PDIA1 and PDIA3 by Biochemical and Computational Approaches. Biomedicines. 9. PMID 34829762 DOI: 10.3390/biomedicines9111533 |
0.574 |
|
| 2021 |
Kurtanović N, Tomašević N, Matić S, Mitrović MM, Kostić DA, Sabatino M, Antonini L, Ragno R, Mladenović M. Human estrogen receptor α antagonists, part 2: Synthesis driven by rational design, in vitro antiproliferative, and in vivo anticancer evaluation of innovative coumarin-related antiestrogens as breast cancer suppressants. European Journal of Medicinal Chemistry. 227: 113869. PMID 34710747 DOI: 10.1016/j.ejmech.2021.113869 |
0.562 |
|
| 2021 |
Mihović N, Tomašević N, Matić S, Mitrović MM, Kostić DA, Sabatino M, Antonini L, Ragno R, Mladenović M. Human Estrogen Receptor α Antagonists. Part 1: 3-D QSAR-Driven Rational Design of Innovative Coumarin-Related Antiestrogens as Breast Cancer Suppressants through Structure-Based and Ligand-Based Studies. Journal of Chemical Information and Modeling. 61: 5028-5053. PMID 34648283 DOI: 10.1021/acs.jcim.1c00530 |
0.603 |
|
| 2021 |
Di Martile M, Garzoli S, Sabatino M, Valentini E, D'Aguanno S, Ragno R, Del Bufalo D. Antitumor effect of Melaleuca alternifolia essential oil and its main component terpinen-4-ol in combination with target therapy in melanoma models. Cell Death Discovery. 7: 127. PMID 34059622 DOI: 10.1038/s41420-021-00510-3 |
0.575 |
|
| 2020 |
Ragno R, Esposito V, Di Mario M, Masiello S, Viscovo M, Cramer RD. Teaching and Learning Computational Drug Design: Student Investigations of 3D Quantitative Structure-Activity Relationships through Web Applications. Journal of Chemical Education. 97: 1922-1930. PMID 33814598 DOI: 10.1021/Acs.Jchemed.0C00117 |
0.352 |
|
| 2020 |
Papa R, Garzoli S, Vrenna G, Sabatino M, Sapienza F, Relucenti M, Donfrancesco O, Fiscarelli EV, Artini M, Selan L, Ragno R. Essential Oils Biofilm Modulation Activity, Chemical and Machine Learning Analysis. Application on Isolates from Cystic Fibrosis Patients. International Journal of Molecular Sciences. 21. PMID 33291608 DOI: 10.3390/ijms21239258 |
0.566 |
|
| 2020 |
Di Martile M, Garzoli S, Ragno R, Del Bufalo D. Essential Oils and Their Main Chemical Components: The Past 20 Years of Preclinical Studies in Melanoma. Cancers. 12. PMID 32948083 DOI: 10.3390/Cancers12092650 |
0.306 |
|
| 2020 |
Rinaldi F, Oliva A, Sabatino M, Imbriano A, Hanieh PN, Garzoli S, Mastroianni CM, De Angelis M, Miele MC, Arnaut M, Di Timoteo F, Marianecci C, Ragno R, Carafa M. Antimicrobial Essential Oil Formulation: Chitosan Coated Nanoemulsions for Nose to Brain Delivery. Pharmaceutics. 12. PMID 32709076 DOI: 10.3390/Pharmaceutics12070678 |
0.566 |
|
| 2020 |
Sabatino M, Fabiani M, Božović M, Garzoli S, Antonini L, Marcocci ME, Palamara AT, De Chiara G, Ragno R. Experimental Data Based Machine Learning Classification Models with Predictive Ability to Select in Vitro Active Antiviral and Non-Toxic Essential Oils. Molecules (Basel, Switzerland). 25. PMID 32466318 DOI: 10.3390/Molecules25102452 |
0.611 |
|
| 2020 |
Matutino Bastos T, Botelho Pereira Soares M, Haddad Franco C, Alcântara L, Antonini L, Sabatino M, Mautone N, Holanda Freitas-Junior L, Moraes CB, Ragno R, Rotili D, Schenkman S, Mai A, Silvio Moretti N. Identification of Inhibitors to Sirtuins Based on Compounds Developed to Human Enzymes. International Journal of Molecular Sciences. 21. PMID 32455951 DOI: 10.3390/Ijms21103659 |
0.652 |
|
| 2020 |
Di Vito M, Bellardi MG, Sanguinetti M, Mondello F, Girolamo A, Barbanti L, Garzoli S, Sabatino M, Ragno R, Vitali A, Palucci I, Posteraro B, Gasbarrini A, Prati GM, Aragona G, et al. Potent Activity of Essential Oil and Hydrolate Against Gut Yeast Isolates from Irritable Bowel Syndrome Patients-The Right Mix for Potential Therapeutic Use. Nutrients. 12. PMID 32392768 DOI: 10.3390/Nu12051329 |
0.58 |
|
| 2020 |
Caroselli S, Zwergel C, Pirolli A, Sabatino M, Xu Z, Kirsch G, Mai A, Colotti G, Altieri F, Canipari R, Valente S, Ragno R. Discovery of the First Human Arylsulfatase A Reversible Inhibitor Impairing Mouse Oocyte Fertilization. Acs Chemical Biology. PMID 32239919 DOI: 10.1021/Acschembio.9B00999 |
0.801 |
|
| 2020 |
Ragno R, Papa R, Patsilinakos A, Vrenna G, Garzoli S, Tuccio V, Fiscarelli E, Selan L, Artini M. Essential oils against bacterial isolates from cystic fibrosis patients by means of antimicrobial and unsupervised machine learning approaches. Scientific Reports. 10: 2653. PMID 32060344 DOI: 10.1038/S41598-020-59553-8 |
0.698 |
|
| 2020 |
Garzoli S, Antonini L, Troiani A, Salvitti C, Giacomello P, Patsilinakos A, Ragno R, Pepi F. Gas-phase structures and thermochemical properties of protonated 5-HMF isomers International Journal of Mass Spectrometry. 447: 116237. DOI: 10.1016/J.Ijms.2019.116237 |
0.685 |
|
| 2019 |
Stazi G, Taglieri L, Nicolai A, Romanelli A, Fioravanti R, Morrone S, Sabatino M, Ragno R, Taurone S, Nebbioso M, Carletti R, Artico M, Valente S, Scarpa S, Mai A. Dissecting the role of novel EZH2 inhibitors in primary glioblastoma cell cultures: effects on proliferation, epithelial-mesenchymal transition, migration, and on the pro-inflammatory phenotype. Clinical Epigenetics. 11: 173. PMID 31791385 DOI: 10.1186/S13148-019-0763-5 |
0.592 |
|
| 2019 |
Ragno R. www.3d-qsar.com: a web portal that brings 3-D QSAR to all electronic devices-the Py-CoMFA web application as tool to build models from pre-aligned datasets. Journal of Computer-Aided Molecular Design. 33: 855-864. PMID 31595406 DOI: 10.1007/S10822-019-00231-X |
0.324 |
|
| 2019 |
Marrocco I, Altieri F, Rubini E, Paglia G, Chichiarelli S, Giamogante F, Macone A, Perugia G, Magliocca FM, Gurtner A, Maras B, Ragno R, Patsilinakos A, Manganaro R, Eufemi M. Shmt2: A Stat3 Signaling New Player in Prostate Cancer Energy Metabolism. Cells. 8. PMID 31500219 DOI: 10.3390/Cells8091048 |
0.686 |
|
| 2019 |
Patsilinakos A, Artini M, Papa R, Sabatino M, Božović M, Garzoli S, Vrenna G, Buzzi R, Manfredini S, Selan L, Ragno R. Machine Learning Analyses on Data including Essential Oil Chemical Composition and In Vitro Experimental Antibiofilm Activities against Species. Molecules (Basel, Switzerland). 24. PMID 30832446 DOI: 10.3390/Molecules24050890 |
0.769 |
|
| 2019 |
Oliva A, Garzoli S, Sabatino M, Tadić V, Costantini S, Ragno R, Božović M. Chemical composition and antimicrobial activity of essential oil of Helichrysum italicum (Roth) G. Don fil. (Asteraceae) from Montenegro. Natural Product Research. 1-4. PMID 30602287 DOI: 10.1080/14786419.2018.1538218 |
0.569 |
|
| 2019 |
Valentini E, Martile MD, Desideri M, Carcasole S, Patsilinakos A, Sabatino M, Mai A, Colotti G, Ragno R, Trisciuoglio D, Bufalo DD. Abstract 2502: Targeting anti-apoptotic Bcl-2 family for cancer therapy Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-2502 |
0.752 |
|
| 2018 |
Stazi G, Battistelli C, Piano V, Mazzone R, Marrocco B, Marchese S, Louie SM, Zwergel C, Antonini L, Patsilinakos A, Ragno R, Viviano M, Sbardella G, Ciogli A, Fabrizi G, et al. Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells. European Journal of Medicinal Chemistry. 163: 722-735. PMID 30576903 DOI: 10.1016/J.Ejmech.2018.11.050 |
0.714 |
|
| 2018 |
Nawrozkij M, Forgione M, Yablokov AS, Lucidi A, Tomaselli D, Patsilinakos A, Panella C, Hailu GS, Kirillov IA, Badia R, Riveira Muñoz E, Crespan E, Armijos-Rivera JI, Cirilli R, Ragno R, et al. Effect of α-Methoxy Substitution on the anti-HIV Activity of Dihydropyrimidin-4(3H)-ones. Journal of Medicinal Chemistry. PMID 30525601 DOI: 10.1021/Acs.Jmedchem.8B01238 |
0.737 |
|
| 2018 |
Mladenović M, Arsić BB, Stanković N, Mihović N, Ragno R, Regan A, Milićević JS, Trtić-Petrović TM, Micić R. The Targeted Pesticides as Acetylcholinesterase Inhibitors: Comprehensive Cross-Organism Molecular Modelling Studies Performed to Anticipate the Pharmacology of Harmfulness to Humans In Vitro. Molecules (Basel, Switzerland). 23. PMID 30200244 DOI: 10.3390/Molecules23092192 |
0.369 |
|
| 2018 |
Patsilinakos A, Ragno R, Carradori S, Petralito S, Cesa S. Carotenoid content of Goji berries: CIELAB, HPLC-DAD analyses and quantitative correlation. Food Chemistry. 268: 49-56. PMID 30064788 DOI: 10.1016/J.Foodchem.2018.06.013 |
0.69 |
|
| 2018 |
Carafa V, Nebbioso A, Cuomo F, Rotili D, Cobellis G, Bontempo P, Baldi A, Spugnini EP, Citro G, Chambery A, Russo R, Ruvo M, Ciana P, Maravigna L, Shaik J, ... ... Ragno R, et al. RIP1-HAT1-SirT complex identification and targeting in treatment and prevention of cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29535128 DOI: 10.1158/1078-0432.Ccr-17-3081 |
0.76 |
|
| 2018 |
Artini M, Patsilinakos A, Papa R, Božović M, Sabatino M, Garzoli S, Vrenna G, Tilotta M, Pepi F, Ragno R, Selan L. Antimicrobial and Antibiofilm Activity and Machine Learning Classification Analysis of Essential Oils from Different Mediterranean Plants against Pseudomonas aeruginosa. Molecules (Basel, Switzerland). 23. PMID 29473844 DOI: 10.3390/Molecules23020482 |
0.771 |
|
| 2018 |
Antonini L, Garzoli S, Ricci A, Troiani A, Salvitti C, Giacomello P, Ragno R, Patsilinakos A, Di Rienzo B, Pepi F. Ab-initio and experimental study of pentose sugar dehydration mechanism in the gas phase. Carbohydrate Research. 19-28. PMID 29428483 DOI: 10.1016/J.Carres.2018.01.007 |
0.705 |
|
| 2018 |
Sabatino M, Rotili D, Patsilinakos A, Forgione M, Tomaselli D, Alby F, Arimondo PB, Mai A, Ragno R. Disruptor of telomeric silencing 1-like (DOT1L): disclosing a new class of non-nucleoside inhibitors by means of ligand-based and structure-based approaches. Journal of Computer-Aided Molecular Design. PMID 29335872 DOI: 10.1007/S10822-018-0096-Z |
0.814 |
|
| 2018 |
Garzoli S, Božović M, Baldisserotto A, Andreotti E, Pepi F, Tadić V, Manfredini S, Ragno R. Sideritis romana L. subsp. purpurea (Tal. ex Benth.) Heywood, a new chemotype from Montenegro. Natural Product Research. 32: 1056-1061. PMID 28927300 DOI: 10.1080/14786419.2017.1378212 |
0.307 |
|
| 2018 |
Garzoli S, Božović M, Baldisserotto A, Sabatino M, Cesa S, Pepi F, Vicentini CB, Manfredini S, Ragno R. Essential oil extraction, chemical analysis and anti-Candida activity of Foeniculum vulgare Miller - new approaches. Natural Product Research. 32: 1254-1259. PMID 28617136 DOI: 10.1080/14786419.2017.1340291 |
0.581 |
|
| 2017 |
Carradori S, Bizzarri B, D'Ascenzio M, De Monte C, Grande R, Rivanera D, Zicari A, Mari E, Sabatino M, Patsilinakos A, Ragno R, Secci D. Synthesis, biological evaluation and quantitative structure-active relationships of 1,3-thiazolidin-4-one derivatives. A promising chemical scaffold endowed with high antifungal potency and low cytotoxicity. European Journal of Medicinal Chemistry. 140: 274-292. PMID 28963991 DOI: 10.1016/J.Ejmech.2017.09.026 |
0.818 |
|
| 2017 |
Di Sotto A, Di Giacomo S, Abete L, Božović M, Parisi OA, Barile F, Vitalone A, Izzo AA, Ragno R, Mazzanti G. Genotoxicity assessment of piperitenone oxide: An in vitro and in silico evaluation. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 106: 506-513. PMID 28606765 DOI: 10.1016/J.Fct.2017.06.021 |
0.312 |
|
| 2017 |
Zwergel C, Czepukojc B, Evain-Bana E, Xu Z, Stazi G, Mori M, Patsilinakos A, Mai A, Botta B, Ragno R, Bagrel D, Kirsch G, Meiser P, Jacob C, Montenarh M, et al. Novel coumarin- and quinolinone-based polycycles as cell division cycle 25-A and -C phosphatases inhibitors induce proliferation arrest and apoptosis in cancer cells. European Journal of Medicinal Chemistry. 134: 316-333. PMID 28431339 DOI: 10.1016/J.Ejmech.2017.04.012 |
0.74 |
|
| 2017 |
Mladenović M, Patsilinakos A, Pirolli A, Sabatino M, Ragno R. Understanding the Molecular Determinant of Reversible Human Monoamine Oxidase B Inhibitors Containing 2H-Chromen-2-One Core: Structure-Based and Ligand-Based Derived Three-Dimensional Quantitative Structure-Activity Relationships Predictive Models. Journal of Chemical Information and Modeling. 57: 787-814. PMID 28291352 DOI: 10.1021/Acs.Jcim.6B00608 |
0.817 |
|
| 2017 |
Papastavrou N, Chatzopoulou M, Ballekova J, Cappiello M, Moschini R, Balestri F, Patsilinakos A, Ragno R, Stefek M, Nicolaou I. Enhancing activity and selectivity in a series of pyrrol-1-yl-1-hydroxypyrazole-based aldose reductase inhibitors: The case of trifluoroacetylation. European Journal of Medicinal Chemistry. 130: 328-335. PMID 28259841 DOI: 10.1016/J.Ejmech.2017.02.053 |
0.77 |
|
| 2017 |
Božović M, Ragno R. Calamintha nepeta (L.) Savi and its Main Essential Oil Constituent Pulegone: Biological Activities and Chemistry. Molecules (Basel, Switzerland). 22. PMID 28216606 DOI: 10.3390/Molecules22020290 |
0.326 |
|
| 2017 |
Božović M, Garzoli S, Sabatino M, Pepi F, Baldisserotto A, Andreotti E, Romagnoli C, Mai A, Manfredini S, Ragno R. Essential Oil Extraction, Chemical Analysis and Anti-Candida Activity of Calamintha nepeta (L.) Savi subsp. glandulosa (Req.) Ball-New Approaches. Molecules (Basel, Switzerland). 22. PMID 28134788 DOI: 10.3390/Molecules22020203 |
0.577 |
|
| 2017 |
Mollica A, Pelliccia S, Famiglini V, Stefanucci A, Macedonio G, Chiavaroli A, Orlando G, Brunetti L, Ferrante C, Pieretti S, Novellino E, Benyhe S, Zador F, Erdei A, Szucs E, ... ... Ragno R, et al. Exploring the first Rimonabant analog-opioid peptide hybrid compound, as bivalent ligand for CB1 and opioid receptors. Journal of Enzyme Inhibition and Medicinal Chemistry. 32: 444-451. PMID 28097916 DOI: 10.1080/14756366.2016.1260565 |
0.702 |
|
| 2017 |
Venditti A, Frezza C, Salutari G, di Cecco M, Ciaschetti G, Oliva A, De Angelis M, Vullo V, Sabatino M, Garzoli S, Pepi F, Ragno R, Serafini M, Bianco A. Composition of the Essential Oil of Coristospermum cuneifolium and Antimicrobial Activity Evaluation Planta Medica International Open. 4: e74-e81. DOI: 10.1055/S-0043-118131 |
0.547 |
|
| 2016 |
Coluccia A, Passacantilli S, Famiglini V, Sabatino M, Patsilinakos A, Ragno R, Mazzoccoli C, Sisinni L, Okuno A, Takikawa O, Silvestri R, La Regina G. New Inhibitors of Indoleamine 2,3-Dioxygenase 1: Molecular Modeling Studies, Synthesis, and Biological Evaluation. Journal of Medicinal Chemistry. 59: 9760-9773. PMID 27690429 DOI: 10.1021/Acs.Jmedchem.6B00718 |
0.817 |
|
| 2016 |
Consalvi S, Poce G, Ragno R, Sabatino M, La Motta C, Sartini S, Calderone V, Martelli A, Ghelardini C, Di Cesare Mannelli L, Biava M. A Series of COX-2 Inhibitors Endowed with NO-Releasing Properties: Synthesis, Biological Evaluation, and Docking Analysis. Chemmedchem. 11: 1804-11. PMID 27229194 DOI: 10.1002/Cmdc.201600086 |
0.661 |
|
| 2016 |
Vavala E, Passariello C, Pepi F, Colone M, Garzoli S, Ragno R, Pirolli A, Stringaro A, Angiolella L. Antibacterial activity of essential oils mixture against PSA. Natural Product Research. 30: 412-8. PMID 25782920 DOI: 10.1080/14786419.2015.1022543 |
0.778 |
|
| 2015 |
Ragno R, Ballante F, Pirolli A, Wickersham RB, Patsilinakos A, Hesse S, Perspicace E, Kirsch G. Vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitors: development and validation of predictive 3-D QSAR models through extensive ligand- and structure-based approaches. Journal of Computer-Aided Molecular Design. 29: 757-76. PMID 26194852 DOI: 10.1007/S10822-015-9859-Y |
0.796 |
|
| 2015 |
Garzoli S, Pirolli A, Vavala E, Di Sotto A, Sartorelli G, Božović M, Angiolella L, Mazzanti G, Pepi F, Ragno R. Multidisciplinary Approach to Determine the Optimal Time and Period for Extracting the Essential Oil from Mentha suaveolens Ehrh. Molecules (Basel, Switzerland). 20: 9640-55. PMID 26016551 DOI: 10.3390/Molecules20069640 |
0.769 |
|
| 2015 |
Božović M, Pirolli A, Ragno R. Mentha suaveolens Ehrh. (Lamiaceae) Essential Oil and Its Main Constituent Piperitenone Oxide: Biological Activities and Chemistry. Molecules (Basel, Switzerland). 20: 8605-33. PMID 25985361 DOI: 10.3390/Molecules20058605 |
0.782 |
|
| 2015 |
Consalvi S, Alfonso S, Di Capua A, Poce G, Pirolli A, Sabatino M, Ragno R, Anzini M, Sartini S, La Motta C, Di Cesare Mannelli L, Ghelardini C, Biava M. Synthesis, biological evaluation and docking analysis of a new series of methylsulfonyl and sulfamoyl acetamides and ethyl acetates as potent COX-2 inhibitors. Bioorganic & Medicinal Chemistry. 23: 810-20. PMID 25596758 DOI: 10.1016/J.Bmc.2014.12.041 |
0.818 |
|
| 2015 |
De Petris A, Crestoni ME, Pirolli A, Rovira C, Iglesias-Fernández J, Chiavarino B, Ragno R, Fornarini S. Binding of azole drugs to heme: A combined MS/MS and computational approach Polyhedron. 90: 245-251. DOI: 10.1016/J.Poly.2015.02.011 |
0.787 |
|
| 2014 |
Rotili D, Tarantino D, Nawrozkij MB, Babushkin AS, Botta G, Marrocco B, Cirilli R, Menta S, Badia R, Crespan E, Ballante F, Ragno R, Esté JA, Maga G, Mai A. Exploring the role of 2-chloro-6-fluoro substitution in 2-alkylthio-6-benzyl-5-alkylpyrimidin-4(3H)-ones: effects in HIV-1-infected cells and in HIV-1 reverse transcriptase enzymes. Journal of Medicinal Chemistry. 57: 5212-25. PMID 24933420 DOI: 10.1021/Jm500284X |
0.748 |
|
| 2014 |
Chatzopoulou M, Patsilinakos A, Vallianatou T, Prnova MS, Zakelj S, Ragno R, Stefek M, Kristl A, Tsantili-Kakoulidou A, Demopoulos VJ. Decreasing acidity in a series of aldose reductase inhibitors: 2-Fluoro-4-(1H-pyrrol-1-yl)phenol as a scaffold for improved membrane permeation. Bioorganic & Medicinal Chemistry. 22: 2194-207. PMID 24630695 DOI: 10.1016/J.Bmc.2014.02.016 |
0.741 |
|
| 2014 |
Civitelli L, Panella S, Marcocci ME, De Petris A, Garzoli S, Pepi F, Vavala E, Ragno R, Nencioni L, Palamara AT, Angiolella L. In vitro inhibition of herpes simplex virus type 1 replication by Mentha suaveolens essential oil and its main component piperitenone oxide. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 21: 857-65. PMID 24629600 DOI: 10.1016/J.Phymed.2014.01.013 |
0.33 |
|
| 2014 |
Ballante F, Caroli A, Wickersham RB, Ragno R. Hsp90 inhibitors, part 1: definition of 3-D QSAutogrid/R models as a tool for virtual screening. Journal of Chemical Information and Modeling. 54: 956-69. PMID 24564321 DOI: 10.1021/Ci400759T |
0.801 |
|
| 2014 |
Caroli A, Ballante F, Wickersham RB, Corelli F, Ragno R. Hsp90 inhibitors, part 2: combining ligand-based and structure-based approaches for virtual screening application. Journal of Chemical Information and Modeling. 54: 970-7. PMID 24555544 DOI: 10.1021/Ci400760A |
0.814 |
|
| 2014 |
Renzi A, Ragno R, Mancinelli R, Franchitto A, Mai A, Gaudio E. COX and VEGFR-2 inhibitors as potentiating agents of new HDAC inhibitors as epigenetic modulators in cancer Italian Journal of Anatomy and Embryology. 119: 163. DOI: 10.13128/Ijae-16003 |
0.414 |
|
| 2013 |
Friggeri L, Ballante F, Ragno R, Musmuca I, De Vita D, Manetti F, Biava M, Scipione L, Di Santo R, Costi R, Feroci M, Tortorella S. Pharmacophore assessment through 3-D QSAR: evaluation of the predictive ability on new derivatives by the application on a series of antitubercular agents. Journal of Chemical Information and Modeling. 53: 1463-74. PMID 23617317 DOI: 10.1021/Ci400132Q |
0.806 |
|
| 2013 |
Perspicace E, Jouan-Hureaux V, Ragno R, Ballante F, Sartini S, La Motta C, Da Settimo F, Chen B, Kirsch G, Schneider S, Faivre B, Hesse S. Design, synthesis and biological evaluation of new classes of thieno[3,2-d]pyrimidinone and thieno[1,2,3]triazine as inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2). European Journal of Medicinal Chemistry. 63: 765-81. PMID 23583911 DOI: 10.1016/J.Ejmech.2013.03.022 |
0.775 |
|
| 2013 |
Ortar G, Morera E, De Petrocellis L, Ligresti A, Schiano Moriello A, Morera L, Nalli M, Ragno R, Pirolli A, Di Marzo V. Biaryl tetrazolyl ureas as inhibitors of endocannabinoid metabolism: modulation at the N-portion and distal phenyl ring. European Journal of Medicinal Chemistry. 63: 118-32. PMID 23474898 DOI: 10.1016/J.Ejmech.2013.02.005 |
0.82 |
|
| 2012 |
Ricci A, Piccolella S, Pepi F, Patsilinakos A, Ragno R, Garzoli S, Giacomello P. Gas-phase basicity of 2-furaldehyde. Journal of Mass Spectrometry : Jms. 47: 1488-94. PMID 23147827 DOI: 10.1002/Jms.3058 |
0.686 |
|
| 2012 |
Ballante F, Musmuca I, Marshall GR, Ragno R. Comprehensive model of wild-type and mutant HIV-1 reverse transciptases. Journal of Computer-Aided Molecular Design. 26: 907-19. PMID 22833004 DOI: 10.1007/S10822-012-9586-6 |
0.799 |
|
| 2012 |
Silvestri L, Ballante F, Mai A, Marshall GR, Ragno R. Histone deacetylase inhibitors: structure-based modeling and isoform-selectivity prediction. Journal of Chemical Information and Modeling. 52: 2215-35. PMID 22762501 DOI: 10.1021/Ci300160Y |
0.802 |
|
| 2012 |
Ballante F, Ragno R. 3-D QSAutogrid/R: an alternative procedure to build 3-D QSAR models. Methodologies and applications. Journal of Chemical Information and Modeling. 52: 1674-85. PMID 22643034 DOI: 10.1021/Ci300123X |
0.751 |
|
| 2012 |
Rotili D, Samuele A, Tarantino D, Ragno R, Musmuca I, Ballante F, Botta G, Morera L, Pierini M, Cirilli R, Nawrozkij MB, Gonzalez E, Clotet B, Artico M, Esté JA, et al. 2-(Alkyl/aryl)amino-6-benzylpyrimidin-4(3H)-ones as inhibitors of wild-type and mutant HIV-1: enantioselectivity studies. Journal of Medicinal Chemistry. 55: 3558-62. PMID 22428851 DOI: 10.1021/Jm201308V |
0.783 |
|
| 2012 |
Nichols DB, Fournet G, Gurukumar KR, Basu A, Lee JC, Sakamoto N, Kozielski F, Musmuca I, Joseph B, Ragno R, Kaushik-Basu N. Inhibition of hepatitis C virus NS5B polymerase by S-trityl-L-cysteine derivatives. European Journal of Medicinal Chemistry. 49: 191-9. PMID 22280819 DOI: 10.1016/J.Ejmech.2012.01.010 |
0.783 |
|
| 2011 |
Ragno R, Gioia U, Laneve P, Bozzoni I, Mai A, Caffarelli E. Identification of small-molecule inhibitors of the XendoU endoribonucleases family. Chemmedchem. 6: 1797-805. PMID 21805647 DOI: 10.1002/Cmdc.201100281 |
0.381 |
|
| 2011 |
Valente S, Tardugno M, Conte M, Cirilli R, Perrone A, Ragno R, Simeoni S, Tramontano A, Massa S, Nebbioso A, Miceli M, Franci G, Brosch G, Altucci L, Mai A. Novel cinnamyl hydroxyamides and 2-aminoanilides as histone deacetylase inhibitors: apoptotic induction and cytodifferentiation activity. Chemmedchem. 6: 698-712. PMID 21374822 DOI: 10.1002/Cmdc.201000535 |
0.785 |
|
| 2011 |
Pepi F, Tata A, Garzoli S, Giacomello P, Ragno R, Patsilinakos A, Fusco MD, D’Annibale A, Cannistraro S, Baldacchini C, Favero G, Frasconi M, Mazzei F. Chemically Modified Multiwalled Carbon Nanotubes Electrodes with Ferrocene Derivatives through Reactive Landing The Journal of Physical Chemistry C. 115: 4863-4871. DOI: 10.1021/Jp1100472 |
0.687 |
|
| 2010 |
Musmuca I, Caroli A, Mai A, Kaushik-Basu N, Arora P, Ragno R. Combining 3-D quantitative structure-activity relationship with ligand based and structure based alignment procedures for in silico screening of new hepatitis C virus NS5B polymerase inhibitors. Journal of Chemical Information and Modeling. 50: 662-76. PMID 20225870 DOI: 10.1021/Ci9004749 |
0.811 |
|
| 2010 |
Castellano S, Milite C, Ragno R, Simeoni S, Mai A, Limongelli V, Novellino E, Bauer I, Brosch G, Spannhoff A, Cheng D, Bedford MT, Sbardella G. Design, synthesis and biological evaluation of carboxy analogues of arginine methyltransferase inhibitor 1 (AMI-1). Chemmedchem. 5: 398-414. PMID 20091730 DOI: 10.1002/Cmdc.200900459 |
0.762 |
|
| 2010 |
MASSA S, MAI A, RAGNO R, PORRETTA GC, RETICO A, SIMONETTI G, ARTICO M. ChemInform Abstract: Antifungal Agents. Part 7. Dichlorophenylpyrrylimidazolylmethane Derivatives: Synthesis and Antifungal Activities. Cheminform. 25: no-no. DOI: 10.1002/CHIN.199429169 |
0.64 |
|
| 2010 |
MASSA S, RAGNO R, PORETTA CG, MAI A, RETICO A, ARTICO M, SIMONETTI N. ChemInform Abstract: Antifungal Agents. Part 2. Synthesis and Antifungal Activities of Aryl- 1H-pyrrol-2-yl-1H-imidazol-1-yl-methane Derivatives with Unsaturated Chains. Cheminform. 24: no-no. DOI: 10.1002/CHIN.199351155 |
0.633 |
|
| 2009 |
Musmuca I, Simeoni S, Caroli A, Ragno R. Small-molecule interferon inducers. Toward the comprehension of the molecular determinants through ligand-based approaches. Journal of Chemical Information and Modeling. 49: 1777-86. PMID 19499914 DOI: 10.1021/Ci900065A |
0.802 |
|
| 2009 |
Mai A, Valente S, Nebbioso A, Simeoni S, Ragno R, Massa S, Brosch G, De Bellis F, Manzo F, Altucci L. New pyrrole-based histone deacetylase inhibitors: binding mode, enzyme- and cell-based investigations. The International Journal of Biochemistry & Cell Biology. 41: 235-47. PMID 18834955 DOI: 10.1016/J.Biocel.2008.09.002 |
0.791 |
|
| 2008 |
Castellano S, Stefancich G, Ragno R, Schewe K, Santoriello M, Caroli A, Hartmann RW, Sbardella G. CYP19 (aromatase): exploring the scaffold flexibility for novel selective inhibitors. Bioorganic & Medicinal Chemistry. 16: 8349-58. PMID 18782670 DOI: 10.1016/J.Bmc.2008.08.046 |
0.82 |
|
| 2008 |
Nawrozkij MB, Rotili D, Tarantino D, Botta G, Eremiychuk AS, Musmuca I, Ragno R, Samuele A, Zanoli S, Armand-Ugón M, Clotet-Codina I, Novakov IA, Orlinson BS, Maga G, Esté JA, et al. 5-Alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a series of anti-HIV-1 agents of the dihydro-alkoxy-benzyl-oxopyrimidine family with peculiar structure-activity relationship profile. Journal of Medicinal Chemistry. 51: 4641-52. PMID 18630898 DOI: 10.1021/Jm800340W |
0.807 |
|
| 2008 |
Ragno R, Simeoni S, Rotili D, Caroli A, Botta G, Brosch G, Massa S, Mai A. Class II-selective histone deacetylase inhibitors. Part 2: alignment-independent GRIND 3-D QSAR, homology and docking studies. European Journal of Medicinal Chemistry. 43: 621-32. PMID 17698257 DOI: 10.1016/J.Ejmech.2007.05.004 |
0.787 |
|
| 2007 |
Ragno R, Coluccia A, La Regina G, Silvestri R. Indolyl aryl sulphones as HIV-1 reverse transcriptase inhibitors: docking and 3D QSAR studies. Expert Opinion On Drug Discovery. 2: 87-114. PMID 23496039 DOI: 10.1517/17460441.2.1.87 |
0.458 |
|
| 2007 |
Mai A, Artico M, Rotili D, Tarantino D, Clotet-Codina I, Armand-Ugón M, Ragno R, Simeoni S, Sbardella G, Nawrozkij MB, Samuele A, Maga G, Esté JA. Synthesis and biological properties of novel 2-aminopyrimidin-4(3H)-ones highly potent against HIV-1 mutant strains. Journal of Medicinal Chemistry. 50: 5412-24. PMID 17910429 DOI: 10.1021/Jm070811E |
0.783 |
|
| 2007 |
Mai A, Valente S, Cheng D, Perrone A, Ragno R, Simeoni S, Sbardella G, Brosch G, Nebbioso A, Conte M, Altucci L, Bedford MT. Synthesis and biological validation of novel synthetic histone/protein methyltransferase inhibitors. Chemmedchem. 2: 987-91. PMID 17458842 DOI: 10.1002/Cmdc.200700023 |
0.721 |
|
| 2007 |
Ragno R, Simeoni S, Castellano S, Vicidomini C, Mai A, Caroli A, Tramontano A, Bonaccini C, Trojer P, Bauer I, Brosch G, Sbardella G. Small molecule inhibitors of histone arginine methyltransferases: homology modeling, molecular docking, binding mode analysis, and biological evaluations. Journal of Medicinal Chemistry. 50: 1241-53. PMID 17323938 DOI: 10.1021/Jm061213N |
0.739 |
|
| 2006 |
De Martino G, La Regina G, Ragno R, Coluccia A, Bergamini A, Ciaprini C, Sinistro A, Maga G, Crespan E, Artico M, Silvestri R. Indolyl aryl sulphones as HIV-1 non-nucleoside reverse transcriptase inhibitors: synthesis, biological evaluation and binding mode studies of new derivatives at indole-2-carboxamide. Antiviral Chemistry & Chemotherapy. 17: 59-77. PMID 17042328 DOI: 10.1177/095632020601700202 |
0.614 |
|
| 2006 |
Mai A, Massa S, Rotili D, Simeoni S, Ragno R, Botta G, Nebbioso A, Miceli M, Altucci L, Brosch G. Synthesis and biological properties of novel, uracil-containing histone deacetylase inhibitors. Journal of Medicinal Chemistry. 49: 6046-56. PMID 17004718 DOI: 10.1021/Jm0605536 |
0.784 |
|
| 2006 |
Mai A, Massa S, Valente S, Simeoni S, Ragno R, Bottoni P, Scatena R, Brosch G. Aroyl-pyrrolyl hydroxyamides: influence of pyrrole C4-phenylacetyl substitution on histone deacetylase inhibition. Chemmedchem. 1: 225-37. PMID 16892355 DOI: 10.1002/Cmdc.200500015 |
0.785 |
|
| 2006 |
Di Santo R, Costi R, Artico M, Ragno R, Lavecchia A, Novellino E, Gavuzzo E, La Torre F, Cirilli R, Cancio R, Maga G. Design, synthesis, biological evaluation, and molecular modeling studies of TIBO-like cyclic sulfones as non-nucleoside HIV-1 reverse transcriptase inhibitors. Chemmedchem. 1: 82-95. PMID 16892340 DOI: 10.1002/Cmdc.200500020 |
0.639 |
|
| 2006 |
Ragno R, Coluccia A, La Regina G, De Martino G, Piscitelli F, Lavecchia A, Novellino E, Bergamini A, Ciaprini C, Sinistro A, Maga G, Crespan E, Artico M, Silvestri R. Design, molecular modeling, synthesis, and anti-HIV-1 activity of new indolyl aryl sulfones. Novel derivatives of the indole-2-carboxamide. Journal of Medicinal Chemistry. 49: 3172-84. PMID 16722636 DOI: 10.1021/Jm0512490 |
0.611 |
|
| 2006 |
Ragno R, Simeoni S, Valente S, Massa S, Mai A. 3-D QSAR studies on histone deacetylase inhibitors. A GOLPE/GRID approach on different series of compounds. Journal of Chemical Information and Modeling. 46: 1420-30. PMID 16711762 DOI: 10.1021/Ci050556B |
0.797 |
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| 2006 |
Manetti F, Tintori C, Armand-Ugón M, Clotet-Codina I, Massa S, Ragno R, Esté JA, Botta M. A combination of molecular dynamics and docking calculations to explore the binding mode of ADS-J1, a polyanionic compound endowed with anti-HIV-1 activity. Journal of Chemical Information and Modeling. 46: 1344-51. PMID 16711753 DOI: 10.1021/Ci050414H |
0.573 |
|
| 2006 |
Manetti F, Tintori C, Armand-Ugon M, Clotet-Codina I, Massa S, Ragno R, Este JA, Botta M. A Combination of Molecular Dynamics and Docking Calculation to Explore the Binding Mode of ADS-J1, a Polyanionic Compound Endowed with anti-HIV-1 Activity. Cheminform. 37. DOI: 10.1002/CHIN.200631203 |
0.527 |
|
| 2005 |
Mai A, Massa S, Lavu S, Pezzi R, Simeoni S, Ragno R, Mariotti FR, Chiani F, Camilloni G, Sinclair DA. Design, synthesis, and biological evaluation of sirtinol analogues as class III histone/protein deacetylase (Sirtuin) inhibitors. Journal of Medicinal Chemistry. 48: 7789-95. PMID 16302818 DOI: 10.1021/Jm050100L |
0.789 |
|
| 2005 |
Cancio R, Silvestri R, Ragno R, Artico M, De Martino G, La Regina G, Crespan E, Zanoli S, Hübscher U, Spadari S, Maga G. High potency of indolyl aryl sulfone nonnucleoside inhibitors towards drug-resistant human immunodeficiency virus type 1 reverse transcriptase mutants is due to selective targeting of different mechanistic forms of the enzyme. Antimicrobial Agents and Chemotherapy. 49: 4546-54. PMID 16251294 DOI: 10.1128/Aac.49.11.4546-4554.2005 |
0.604 |
|
| 2005 |
De Martino G, La Regina G, Di Pasquali A, Ragno R, Bergamini A, Ciaprini C, Sinistro A, Maga G, Crespan E, Artico M, Silvestri R. Novel 1-[2-(diarylmethoxy)ethyl]-2-methyl-5-nitroimidazoles as HIV-1 non-nucleoside reverse transcriptase inhibitors. A structure-activity relationship investigation. Journal of Medicinal Chemistry. 48: 4378-88. PMID 15974590 DOI: 10.1021/Jm050273A |
0.633 |
|
| 2005 |
Di Santo R, Costi R, Artico M, Ragno R, Greco G, Novellino E, Marchand C, Pommier Y. Design, synthesis and biological evaluation of heteroaryl diketohexenoic and diketobutanoic acids as HIV-1 integrase inhibitors endowed with antiretroviral activity. Farmaco (Società Chimica Italiana : 1989). 60: 409-17. PMID 15910813 DOI: 10.1016/J.Farmac.2005.03.008 |
0.625 |
|
| 2005 |
Mai A, Artico M, Ragno R, Sbardella G, Massa S, Musiu C, Mura M, Marturana F, Cadeddu A, Maga G, La Colla P. 5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3H) -ones, a new series of potent, broad-spectrum non-nucleoside reverse transcriptase inhibitors belonging to the DABO family Bioorganic and Medicinal Chemistry. 13: 2065-2077. PMID 15727860 DOI: 10.1016/J.Bmc.2005.01.005 |
0.706 |
|
| 2005 |
Agamennone M, Campestre C, Preziuso S, Consalvi V, Crucianelli M, Mazza F, Politi V, Ragno R, Tortorella P, Gallina C. Synthesis and evaluation of new tripeptide phosphonate inhibitors of MMP-8 and MMP-2. European Journal of Medicinal Chemistry. 40: 271-9. PMID 15725496 DOI: 10.1016/J.Ejmech.2004.10.013 |
0.316 |
|
| 2005 |
Ragno R, Artico M, De Martino G, La Regina G, Coluccia A, Di Pasquali A, Silvestri R. Docking and 3-D QSAR studies on indolyl aryl sulfones. Binding mode exploration at the HIV-1 reverse transcriptase non-nucleoside binding site and design of highly active N-(2-hydroxyethyl)carboxamide and N-(2-hydroxyethyl)carbohydrazide derivatives. Journal of Medicinal Chemistry. 48: 213-23. PMID 15634015 DOI: 10.1021/Jm040854K |
0.63 |
|
| 2005 |
Ragno R, Frasca S, Manetti F, Brizzi A, Massa S. HIV-reverse transcriptase inhibition: Inclusion of ligand-induced fit by cross-docking studies Journal of Medicinal Chemistry. 48: 200-212. PMID 15634014 DOI: 10.1021/Jm0493921 |
0.6 |
|
| 2005 |
Mai A, Massa S, Rotili D, Cerbara I, Valente S, Pezzi R, Simeoni S, Ragno R. Histone Deacetylation in Epigenetics: An Attractive Target for Anticancer Therapy Cheminform. 36. DOI: 10.1002/CHIN.200528271 |
0.716 |
|
| 2004 |
Costi R, Di Santo R, Artico M, Roux A, Ragno R, Massa S, Tramontano E, La Colla M, Loddo R, Marongiu ME, Pani A, La Colla P. 6-aryl-2,4-dioxo-5-hexenoic acids, novel integrase inhibitors active against HIV-1 multiplication in cell-based assays. Bioorganic & Medicinal Chemistry Letters. 14: 1745-9. PMID 15026063 DOI: 10.1016/J.Bmcl.2004.01.037 |
0.7 |
|
| 2004 |
Ragno R, Mai A, Massa S, Cerbara I, Valente S, Bottoni P, Scatena R, Jesacher F, Loidl P, Brosch G. 3-(4-Aroyl-1-methyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides as a New Class of Synthetic Histone Deacetylase Inhibitors. 3. Discovery of Novel Lead Compounds through Structure-Based Drug Design and Docking Studies Journal of Medicinal Chemistry. 47: 1351-1359. PMID 14998325 DOI: 10.1021/Jm031036F |
0.665 |
|
| 2004 |
Mai A, Massa S, Cerbara I, Valente S, Ragno R, Bottoni P, Scatena R, Loidl P, Brosch G. 3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamides as a new class of synthetic histone deacetylase inhibitors. 2. Effect of pyrrole-C2 and/or -C4 substitutions on biological activity. Journal of Medicinal Chemistry. 47: 1098-109. PMID 14971890 DOI: 10.1021/Jm030990+ |
0.608 |
|
| 2004 |
Ragno R, Mai A, Sbardella G, Artico M, Massa S, Musiu C, Mura M, Marturana F, Cadeddu A, La Colla P. Computer-aided design, synthesis, and anti-HIV-1 activity in vitro of 2-alkylamino-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as novel potent non-nucleoside reverse transcriptase inhibitors, also active against the Y181C variant. Journal of Medicinal Chemistry. 47: 928-34. PMID 14761194 DOI: 10.1021/Jm0309856 |
0.719 |
|
| 2004 |
Costi R, Di Santo R, Artico M, Massa S, Ragno R, Loddo R, La Colla M, Tramontano E, La Colla P, Pani A. 2,6-Bis(3,4,5-trihydroxybenzylydene) derivatives of cyclohexanone: Novel potent HIV-1 integrase inhibitors that prevent HIV-1 multiplication in cell-based assays Bioorganic and Medicinal Chemistry. 12: 199-215. PMID 14697785 DOI: 10.1016/J.Bmc.2003.10.005 |
0.735 |
|
| 2003 |
Mai A, Artico M, Esposito M, Ragno R, Sbardella G, Massa S. Synthesis and biological evaluation of enantiomerically pure pyrrolyl-oxazolidinones as a new class of potent and selective monoamine oxidase type A inhibitors. Farmaco (Societa Chimica Italiana : 1989). 58: 231-41. PMID 12620419 DOI: 10.1016/S0014-827X(03)00016-8 |
0.72 |
|
| 2003 |
Mai A, Massa S, Ragno R, Cerbara I, Jesacher F, Loidl P, Brosch G. 3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-alkylamides as a new class of synthetic histone deacetylase inhibitors. 1. Design, synthesis, biological evaluation, and binding mode studies performed through three different docking procedures. Journal of Medicinal Chemistry. 46: 512-24. PMID 12570373 DOI: 10.1021/Jm021070E |
0.63 |
|
| 2002 |
Di Santo R, Costi R, Artico M, Massa S, Ragno R, Marshall GR, La Colla P. Design, synthesis and QSAR studies on N-aryl heteroarylisopropanolamines, a new class of non-peptidic HIV-1 protease inhibitors. Bioorganic & Medicinal Chemistry. 10: 2511-26. PMID 12057640 DOI: 10.1016/S0968-0896(02)00119-0 |
0.763 |
|
| 2002 |
Mai A, Massa S, Ragno R, Esposito M, Sbardella G, Nocca G, Scatena R, Jesacher F, Loidl P, Brosch G. Binding mode analysis of 3-(4-benzoyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamide: a new synthetic histone deacetylase inhibitor inducing histone hyperacetylation, growth inhibition, and terminal cell differentiation. Journal of Medicinal Chemistry. 45: 1778-84. PMID 11960489 DOI: 10.1021/Jm011088+ |
0.594 |
|
| 2002 |
Silvestri R, Artico M, De Martino G, Ragno R, Massa S, Loddo R, Murgioni C, Loi AG, La Colla P, Pani A. Synthesis, biological evaluation, and binding mode of novel 1-[2-(diarylmethoxy)ethyl]-2-methyl-5-nitroimidazoles targeted at the HIV-1 reverse transcriptase. Journal of Medicinal Chemistry. 45: 1567-76. PMID 11931611 DOI: 10.1021/Jm010904A |
0.721 |
|
| 2001 |
Mai A, Sbardella G, Artico M, Ragno R, Massa S, Novellino E, Greco G, Lavecchia A, Musiu C, La Colla M, Murgioni C, La Colla P, Loddo R. Structure-based design, synthesis, and biological evaluation of conformationally restricted novel 2-alkylthio-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as non-nucleoside inhibitors of HIV-1 reverse transcriptase. Journal of Medicinal Chemistry. 44: 2544-54. PMID 11472208 DOI: 10.1021/Jm010853H |
0.723 |
|
| 2001 |
Massa S, Mai A, Sbardella G, Esposito M, Ragno R, Loidl P, Brosch G. 3-(4-aroyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides, a new class of synthetic histone deacetylase inhibitors. Journal of Medicinal Chemistry. 44: 2069-72. PMID 11405644 DOI: 10.1021/Jm015515V |
0.617 |
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| 2001 |
Quaglia M, Mai A, Sbardella G, Artico M, Ragno R, Massa S, del Piano D, Setzu G, Doratiotto S, Cotichini V. Chiral resolution and molecular modeling investigation of rac-2-cyclopentylthio-6-[1-(2,6-difluorophenyl)ethyl]-3,4-dihydro-5-methylpyrimidin-4(3H)-one (MC-1047), a potent anti-HIV-1 reverse transcriptase agent of the DABO class. Chirality. 13: 75-80. PMID 11170249 DOI: 10.1002/1520-636X(2001)13:2<75::Aid-Chir1001>3.0.Co;2-W |
0.698 |
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| 2000 |
Ragno R, Marshall GR, Di Santo R, Costi R, Massa S, Rompei R, Artico M. Antimycobacterial pyrroles: synthesis, anti-Mycobacterium tuberculosis activity and QSAR studies. Bioorganic & Medicinal Chemistry. 8: 1423-32. PMID 10896119 DOI: 10.1016/S0968-0896(00)00061-4 |
0.776 |
|
| 1999 |
Marshall GR, Ragno R, Makara GM, Arimoto R, Kisselev O. Bound conformations for ligands for G-protein coupled receptors Letters in Peptide Science. 6: 283-288. DOI: 10.1007/Bf02443423 |
0.672 |
|
| 1998 |
Ettorre A, Artico M, Mai A, Ragno R, Porretta GC, Massa S. Crystal structure of 2-[5-(4-carbethoxyphenoxy)pentanoyl]-5-chlorothiophene, C18H19O4CIS Zeitschrift FüR Kristallographie - New Crystal Structures. 213: 129-130. DOI: 10.1524/Ncrs.1998.213.14.129 |
0.581 |
|
| 1997 |
Artico M, Botta M, Corelli F, Mai A, Massa S, Ragno R. Investigation on QSAR and binding mode of a new class of human rhinovirus-14 inhibitors by CoMFA and docking experiments. Bioorganic & Medicinal Chemistry. 4: 1715-24. PMID 8931942 DOI: 10.1016/0968-0896(96)00184-8 |
0.721 |
|
| 1996 |
Tafi A, Anastassopoulou J, Theophanides T, Botta M, Corelli F, Massa S, Artico M, Costi R, Di Santo R, Ragno R. Molecular modeling of azole antifungal agents active against Candida albicans. 1. A comparative molecular field analysis study Journal of Medicinal Chemistry. 39: 1227-1235. PMID 8632429 DOI: 10.1021/Jm950385+ |
0.726 |
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| 1996 |
Mai A, Artico M, Massa S, Ragno R, De Montis A, Comas S, Spiga M, La Colla P. Methyl-2-Thienylketopolymethyleneoxyphenyl Derivatives of Alkyl-Substituted 4,5-Dihydro-Oxazoles with Anti-Human Picornavirus Activity Antiviral Chemistry and Chemotherapy. 7: 213-220. DOI: 10.1177/095632029600700407 |
0.693 |
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| 1995 |
Massa S, Corelli F, Artico M, Mai A, Ragno R, De Montis A, Loi AG, Corrias S, Marongiu ME, La Colla P. [[[(Thienylcarbonyl)alkyl]oxy]phenyl]- and [[[(pyrrylcarbonyl)alkyl]oxy]phenyl]oxazoline derivatives with potent and selective antihuman rhinovirus activity. Journal of Medicinal Chemistry. 38: 803-9. PMID 7877145 DOI: 10.1021/Jm00005A007 |
0.719 |
|
| 1993 |
Massa S, Ragno R, Porretta GC, Mai A, Retico A, Artico M, Simonetti N. Antifungal agents, II: Synthesis and antifungal activities of aryl-1H-pyrrol-2-yl-1H-imidazol-1-yl-methane derivatives with unsaturated chains. Archiv Der Pharmazie. 326: 539-46. PMID 8239946 DOI: 10.1002/Ardp.19933260909 |
0.673 |
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| 1991 |
Massa S, Artico M, Mai A, Ragno R, Corelli F, Pani A, Marongiu M, Tramontano E, La Colla P. Synthesis of new disoxaril analogues with potent and selective anti-human rhinovirus 14 activity Bioorganic & Medicinal Chemistry Letters. 1: 575-578. DOI: 10.1016/S0960-894X(01)81153-7 |
0.685 |
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