| Year |
Citation |
Score |
| 2024 |
Lombardo AT, Mitchell CAR, Zaman R, McDermitt DJ, Bretscher A. ARHGAP18-ezrin functions as an autoregulatory module for RhoA in the assembly of distinct actin-based structures. Elife. 13. PMID 38193818 DOI: 10.7554/eLife.83526 |
0.35 |
|
| 2022 |
Gingras RM, Sulpizio AM, Park J, Bretscher A. High-resolution secretory timeline from vesicle formation at the Golgi to fusion at the plasma membrane in S. cerevisiae. Elife. 11. PMID 36331188 DOI: 10.7554/eLife.78750 |
0.302 |
|
| 2022 |
Sulpizio A, Herpin L, Gingras R, Liu W, Bretscher A. Generation and characterization of conditional yeast mutants affecting each of the two essential functions of the scaffolding proteins Boi1/2 and Bem1. G3 (Bethesda, Md.). PMID 36218417 DOI: 10.1093/g3journal/jkac273 |
0.597 |
|
| 2022 |
Miller MR, McDermitt DJ, Sauvanet C, Lombardo AT, Zaman R, Bretscher A. The RabGAPs EPI64A and EPI64B regulate the apical structure of epithelial cells . Molecular Biology of the Cell. 33: ar8. PMID 34757852 DOI: 10.1091/mbc.E21-05-0268 |
0.369 |
|
| 2021 |
Zaman R, Lombardo A, Sauvanet C, Viswanatha R, Awad V, Bonomo LE, McDermitt D, Bretscher A. Effector-mediated ERM activation locally inhibits RhoA activity to shape the apical cell domain. The Journal of Cell Biology. 220. PMID 33836044 DOI: 10.1083/jcb.202007146 |
0.783 |
|
| 2020 |
Gingras RM, Lwin KM, Miller AM, Bretscher A. Yeast Rgd3 is a phospho-regulated F-BAR-containing RhoGAP involved in the regulation of Rho3 distribution and cell morphology. Molecular Biology of the Cell. mbcE20050288. PMID 32941095 DOI: 10.1091/Mbc.E20-05-0288 |
0.476 |
|
| 2018 |
Pelaseyed T, Bretscher A. Regulation of actin-based apical structures on epithelial cells. Journal of Cell Science. 131. PMID 30333133 DOI: 10.1242/Jcs.221853 |
0.824 |
|
| 2018 |
Shin M, van Leeuwen J, Boone C, Bretscher A. Yeast Aim21/Tda2 both regulates free actin by reducing barbed end assembly and forms a complex with Cap1/Cap2 to balance actin assembly between patches and cables. Molecular Biology of the Cell. PMID 29467252 DOI: 10.1091/Mbc.E17-10-0592 |
0.484 |
|
| 2017 |
Pelaseyed T, Sauvanet C, Viswanatha R, Filter JJ, Goldberg ML, Bretscher A. Ezrin activation by LOK phosphorylation involves a PIP2-dependent wedge mechanism. Elife. 6. PMID 28430576 DOI: 10.7554/Elife.22759 |
0.826 |
|
| 2017 |
Pelaseyed T, Viswanatha R, Sauvanet C, Filter JJ, Goldberg ML, Bretscher A. Author response: Ezrin activation by LOK phosphorylation involves a PIP2-dependent wedge mechanism Elife. DOI: 10.7554/Elife.22759.021 |
0.768 |
|
| 2016 |
Lwin KM, Li D, Bretscher A. Kinesin-related Smy1 enhances the Rab-dependent association of myosin-V with secretory cargo. Molecular Biology of the Cell. PMID 27307583 DOI: 10.1091/Mbc.E16-03-0185 |
0.466 |
|
| 2015 |
Sauvanet C, Wayt J, Pelaseyed T, Bretscher A. Structure, regulation, and functional diversity of microvilli on the apical domain of epithelial cells. Annual Review of Cell and Developmental Biology. 31: 593-621. PMID 26566117 DOI: 10.1146/Annurev-Cellbio-100814-125234 |
0.813 |
|
| 2015 |
Sauvanet C, Garbett D, Bretscher A. The function and dynamics of the apical scaffolding protein E3KARP are regulated by cell-cycle phosphorylation. Molecular Biology of the Cell. 26: 3615-27. PMID 26310448 DOI: 10.1091/Mbc.E15-07-0498 |
0.822 |
|
| 2015 |
Donovan KW, Bretscher A. Tracking individual secretory vesicles during exocytosis reveals an ordered and regulated process. The Journal of Cell Biology. 210: 181-9. PMID 26169352 DOI: 10.1083/Jcb.201501118 |
0.811 |
|
| 2015 |
Donovan KW, Bretscher A. Head-to-tail regulation is critical for the in vivo function of myosin V. The Journal of Cell Biology. 209: 359-65. PMID 25940346 DOI: 10.1083/Jcb.201411010 |
0.8 |
|
| 2015 |
Sauvanet C, Wayt J, Pelaseyed T, Bretscher A. Structure, Regulation, and Functional Diversity of Microvilli on the Apical Domain of Epithelial Cells Annual Review of Cell and Developmental Biology. 31: 593-621. DOI: 10.1146/annurev-cellbio-100814-125234 |
0.798 |
|
| 2015 |
Sauvanet C, Garbett D, Bretscher A. The function and dynamics of the apical scaffolding protein E3KARP are regulated by cell-cycle phosphorylation Molecular Biology of the Cell. 26: 3615-3627. DOI: 10.1091/mbc.E15-07-0498 |
0.794 |
|
| 2015 |
Donovan KW, Bretscher A. Head-to-tail regulation is critical for the in vivo function of myosin V Journal of Cell Biology. 209: 359-365. DOI: 10.1085/Jgp.1456Oia25 |
0.79 |
|
| 2015 |
Donovan KW, Bretscher A. Tracking individual secretory vesicles during exocytosis reveals an ordered and regulated process Journal of Cell Biology. 210: 181-189. DOI: 10.1083/jcb.201501118 |
0.774 |
|
| 2014 |
Xu L, Bretscher A. Rapid glucose depletion immobilizes active myosin V on stabilized actin cables. Current Biology : Cb. 24: 2471-9. PMID 25308080 DOI: 10.1016/j.cub.2014.09.017 |
0.325 |
|
| 2014 |
Garbett D, Bretscher A. The surprising dynamics of scaffolding proteins Molecular Biology of the Cell. 25: 2315-2319. PMID 25122925 DOI: 10.1091/Mbc.E14-04-0878 |
0.789 |
|
| 2014 |
Wayt J, Bretscher A. Cordon Bleu serves as a platform at the basal region of microvilli, where it regulates microvillar length through its WH2 domains. Molecular Biology of the Cell. 25: 2817-27. PMID 25031432 DOI: 10.1091/Mbc.E14-06-1131 |
0.831 |
|
| 2014 |
Viswanatha R, Bretscher A, Garbett D. Dynamics of ezrin and EBP50 in regulating microvilli on the apical aspect of epithelial cells Biochemical Society Transactions. 42: 189-194. PMID 24450650 DOI: 10.1042/Bst20130263 |
0.812 |
|
| 2014 |
Xu L, Bretscher A. Rapid glucose depletion immobilizes active myosin v on stabilized actin cables Current Biology. 24: 2471-2479. DOI: 10.1016/J.Cub.2014.09.017 |
0.411 |
|
| 2013 |
Bretscher A. Deconstructing formin-dependent actin cable assembly Proceedings of the National Academy of Sciences of the United States of America. 110: 18744-18745. PMID 24179137 DOI: 10.1073/Pnas.1318683110 |
0.486 |
|
| 2013 |
Viswanatha R, Wayt J, Ohouo PY, Smolka MB, Bretscher A. Interactome analysis reveals ezrin can adopt multiple conformational states. The Journal of Biological Chemistry. 288: 35437-51. PMID 24151071 DOI: 10.1074/Jbc.M113.505669 |
0.8 |
|
| 2013 |
Chernyakov I, Santiago-Tirado F, Bretscher A. Active segregation of yeast mitochondria by Myo2 is essential and mediated by Mmr1 and Ypt11 Current Biology. 23: 1818-1824. PMID 24012315 DOI: 10.1016/J.Cub.2013.07.053 |
0.369 |
|
| 2013 |
Garbett D, Sauvanet C, Viswanatha R, Bretscher A. The tails of apical scaffolding proteins EBP50 and E3KARP regulate their localization and dynamics Molecular Biology of the Cell. 24: 3381-3392. PMID 23985317 DOI: 10.1091/Mbc.E13-06-0330 |
0.821 |
|
| 2012 |
Viswanatha R, Ohouo PY, Smolka MB, Bretscher A. Local phosphocycling mediated by LOK/SLK restricts ezrin function to the apical aspect of epithelial cells. The Journal of Cell Biology. 199: 969-84. PMID 23209304 DOI: 10.1083/Jcb.201207047 |
0.78 |
|
| 2012 |
Donovan KW, Bretscher A. Myosin-V Is Activated by Binding Secretory Cargo and Released in Coordination with Rab/Exocyst Function Developmental Cell. 23: 769-781. PMID 23079598 DOI: 10.1016/J.Devcel.2012.09.001 |
0.808 |
|
| 2012 |
Garbett D, Bretscher A. PDZ interactions regulate rapid turnover of the scaffolding protein EBP50 in microvilli Journal of Cell Biology. 198: 195-203. PMID 22801783 DOI: 10.1083/Jcb.201204008 |
0.835 |
|
| 2012 |
Mi-Mi L, Votra S, Kemphues K, Bretscher A, Pruyne D. Z-line formins promote contractile lattice growth and maintenance in striated muscles of C. elegans Journal of Cell Biology. 198: 87-102. PMID 22753896 DOI: 10.1083/Jcb.201202053 |
0.745 |
|
| 2012 |
Sher I, Hanemann OC, Karplus AP, Bretscher A. The Tumor Suppressor Merlin Controls Growth in Its Open State, and Phosphorylation Converts It to a Less-Active More-Closed State Developmental Cell. 22: 703-705. PMID 22516197 DOI: 10.1016/J.Devcel.2012.03.008 |
0.389 |
|
| 2012 |
Hokanson DE, Bretscher AP. EPI64 interacts with Slp1/JFC1 to coordinate Rab8a and Arf6 membrane trafficking. Molecular Biology of the Cell. 23: 701-15. PMID 22219378 DOI: 10.1091/Mbc.E11-06-0521 |
0.509 |
|
| 2012 |
Liu W, Santiago-Tirado FH, Bretscher A. Yeast formin Bni1p has multiple localization regions that function in polarized growth and spindle orientation Molecular Biology of the Cell. 23: 412-422. PMID 22160598 DOI: 10.1091/Mbc.E11-07-0631 |
0.649 |
|
| 2011 |
Santiago-Tirado FH, Bretscher A. Membrane-trafficking sorting hubs: Cooperation between PI4P and small GTPases at the trans-Golgi network Trends in Cell Biology. 21: 515-525. PMID 21764313 DOI: 10.1016/J.Tcb.2011.05.005 |
0.386 |
|
| 2011 |
Santiago-Tirado FH, Legesse-Miller A, Schott D, Bretscher A. PI4P and Rab Inputs Collaborate in Myosin-V-Dependent Transport of Secretory Compartments in Yeast Developmental Cell. 20: 47-59. PMID 21238924 DOI: 10.1016/J.Devcel.2010.11.006 |
0.809 |
|
| 2011 |
LaLonde DP, Bretscher A. The UBX protein SAKS1 negatively regulates endoplasmic reticulum-associated degradation and p97-dependent degradation Journal of Biological Chemistry. 286: 4892-4901. PMID 21135095 DOI: 10.1074/Jbc.M110.158030 |
0.403 |
|
| 2010 |
Garbett D, LaLonde DP, Bretscher A. The scaffolding protein EBP50 regulates microvillar assembly in a phosphorylation-dependent manner Journal of Cell Biology. 191: 397-413. PMID 20937695 DOI: 10.1085/Jgp1365Oia5 |
0.831 |
|
| 2010 |
Fehon RG, McClatchey AI, Bretscher A. Organizing the cell cortex: the role of ERM proteins. Nature Reviews. Molecular Cell Biology. 11: 276-87. PMID 20308985 DOI: 10.1038/Nrm2866 |
0.464 |
|
| 2010 |
Lalonde DP, Garbett D, Bretscher A. A regulated complex of the scaffolding proteins PDZK1 and EBP50 with ezrin contribute to microvillar organization Molecular Biology of the Cell. 21: 1519-1529. PMID 20237154 DOI: 10.1091/Mbc.E10-01-0008 |
0.823 |
|
| 2010 |
Gao L, Liu W, Bretscher A. The yeast formin Bnr1p has two localization regions that show spatially and temporally distinct association with septin structures. Molecular Biology of the Cell. 21: 1253-62. PMID 20147448 DOI: 10.1091/Mbc.E09-10-0861 |
0.526 |
|
| 2010 |
Fehon RG, McClatchey AI, Bretscher A. Erratum: Organizing the cell cortex: the role of ERM proteins Nature Reviews Molecular Cell Biology. 11: 674-674. DOI: 10.1038/Nrm2955 |
0.348 |
|
| 2009 |
Bretscher A. Epithelial Polarity: Dual Lkb1 Pathways Regulate Apical Microvilli Developmental Cell. 16: 491-492. PMID 19386258 DOI: 10.1016/J.Devcel.2009.03.012 |
0.357 |
|
| 2009 |
Ilani T, Vasiliver-Shamis G, Vardhana S, Bretscher A, Dustin ML. T cell antigen receptor signaling and immunological synapse stability require myosin IIA Nature Immunology. 10: 531-539. PMID 19349987 DOI: 10.1038/Ni.1723 |
0.74 |
|
| 2009 |
Gao L, Bretscher A. Polarized growth in budding yeast in the absence of a localized formin. Molecular Biology of the Cell. 20: 2540-8. PMID 19297522 DOI: 10.1091/Mbc.E09-03-0194 |
0.398 |
|
| 2009 |
LaLonde DP, Bretscher A. The scaffold protein PDZK1 undergoes a head-to-tail intramolecular association that negatively regulates its interaction with EBP50 Biochemistry. 48: 2261-2271. PMID 19173579 DOI: 10.1021/Bi802089K |
0.435 |
|
| 2008 |
Gao L, Bretscher A. Analysis of unregulated formin activity reveals how yeast can balance F-actin assembly between different microfilament-based organizations. Molecular Biology of the Cell. 19: 1474-84. PMID 18234843 DOI: 10.1091/Mbc.E07-05-0520 |
0.49 |
|
| 2007 |
Ilani T, Khanna C, Zhou M, Veenstra TD, Bretscher A. Immune synapse formation requires ZAP-70 recruitment by ezrin and CD43 removal by moesin Journal of Cell Biology. 179: 733-746. PMID 18025306 DOI: 10.1083/Jcb.200707199 |
0.774 |
|
| 2007 |
Amin NM, Hu K, Pruyne D, Terzic D, Bretscher A, Liu J. A Zn-finger/FH2-domain containing protein, FOZI-1, acts redundantly with CeMyoD to specify striated body wall muscle fates in the Caenorhabditis elegans postembryonic mesoderm. Development (Cambridge, England). 134: 19-29. PMID 17138663 DOI: 10.1242/Dev.02709 |
0.75 |
|
| 2007 |
Li Q, Nance MR, Kulikauskas R, Nyberg K, Fehon R, Karplus PA, Bretscher A, Tesmer JJ. Self-masking in an intact ERM-merlin protein: an active role for the central alpha-helical domain. Journal of Molecular Biology. 365: 1446-59. PMID 17134719 DOI: 10.1016/J.Jmb.2006.10.075 |
0.666 |
|
| 2006 |
Hanono A, Garbett D, Reczek D, Chambers DN, Bretscher A. EPI64 regulates microvillar subdomains and structure Journal of Cell Biology. 175: 803-813. PMID 17145964 DOI: 10.1083/Jcb.200604046 |
0.806 |
|
| 2006 |
Legesse-Miller A, Zhang S, Santiago-Tirado FH, Van Pelt CK, Bretscher A. Regulated phosphorylation of budding yeast's essential myosin V heavy chain, Myo2p Molecular Biology of the Cell. 17: 1812-1821. PMID 16467380 DOI: 10.1091/Mbc.E05-09-0872 |
0.435 |
|
| 2005 |
Bretscher A. Microtubule tips redirect actin assembly Developmental Cell. 8: 458-459. PMID 15809028 DOI: 10.1016/J.Devcel.2005.03.008 |
0.43 |
|
| 2005 |
Chambers DN, Bretscher A. Ezrin mutants affecting dimerization and activation Biochemistry. 44: 3926-3932. PMID 15751968 DOI: 10.1021/Bi0480382 |
0.72 |
|
| 2004 |
Pruyne D, Legesse-Miller A, Gao L, Dong Y, Bretscher A. Mechanisms of polarized growth and organelle segregation in yeast. Annual Review of Cell and Developmental Biology. 20: 559-91. PMID 15473852 DOI: 10.1146/Annurev.Cellbio.20.010403.103108 |
0.776 |
|
| 2004 |
Pruyne D, Gao L, Bi E, Bretscher A. Stable and dynamic axes of polarity use distinct formin isoforms in budding yeast. Molecular Biology of the Cell. 15: 4971-89. PMID 15371545 DOI: 10.1091/Mbc.E04-04-0296 |
0.78 |
|
| 2004 |
Hayashi H, Szászi K, Coady-Osberg N, Furuya W, Bretscher AP, Orlowski J, Grinstein S. Inhibition and redistribution of NHE3, the apical Na+/H+ exchanger, by Clostridium difficile toxin B. The Journal of General Physiology. 123: 491-504. PMID 15078917 DOI: 10.1085/Jgp.200308979 |
0.361 |
|
| 2004 |
Finnerty CM, Chambers D, Ingraffea J, Faber HR, Karplus PA, Bretscher A. The EBP50-moesin interaction involves a binding site regulated by direct masking on the FERM domain Journal of Cell Science. 117: 1547-1552. PMID 15020681 DOI: 10.1242/Jcs.01038 |
0.814 |
|
| 2004 |
Nawrot M, West K, Huang J, Possin DE, Bretscher A, Crabb JW, Saari JC. Cellular retinaldehyde-binding protein interacts with ERM-binding phosphoprotein 50 in retinal pigment epithelium. Investigative Ophthalmology & Visual Science. 45: 393-401. PMID 14744877 DOI: 10.1167/Iovs.03-0989 |
0.476 |
|
| 2003 |
Gundersen GG, Bretscher A. Cell biology. Microtubule asymmetry. Science (New York, N.Y.). 300: 2040-1. PMID 12829769 DOI: 10.1126/Science.1084938 |
0.36 |
|
| 2003 |
Dong Y, Pruyne D, Bretscher A. Formin-dependent actin assembly is regulated by distinct modes of Rho signaling in yeast Journal of Cell Biology. 161: 1081-1092. PMID 12810699 DOI: 10.1083/Jcb.200212040 |
0.784 |
|
| 2003 |
Bretscher A. Polarized growth and organelle segregation in yeast: The tracks, motors, and receptors Journal of Cell Biology. 160: 811-816. PMID 12642608 DOI: 10.1083/Jcb.200301035 |
0.405 |
|
| 2003 |
Smith WJ, Nassar N, Bretscher A, Cerione RA, Karplus PA. Structure of the active N-terminal domain of Ezrin. Conformational and mobility changes identify keystone interactions. The Journal of Biological Chemistry. 278: 4949-56. PMID 12429733 DOI: 10.1074/Jbc.M210601200 |
0.646 |
|
| 2002 |
Schott D, Huffaker T, Bretscher A. Microfilaments and microtubules: The news from yeast Current Opinion in Microbiology. 5: 564-574. PMID 12457699 DOI: 10.1016/S1369-5274(02)00369-7 |
0.823 |
|
| 2002 |
Bretscher A, Edwards K, Fehon RG. ERM proteins and merlin: integrators at the cell cortex. Nature Reviews. Molecular Cell Biology. 3: 586-99. PMID 12154370 DOI: 10.1038/Nrm882 |
0.441 |
|
| 2002 |
Pruyne D, Evangelista M, Yang C, Bi E, Zigmond S, Bretscher A, Boone C. Role of formins in actin assembly: Nucleation and barbed-end association Science. 297: 612-615. PMID 12052901 DOI: 10.1126/Science.1072309 |
0.788 |
|
| 2002 |
Hoe NP, Ireland RM, DeLeo FR, Gowen BB, Dorward DW, Voyich JM, Liu M, Burns EH, Culnan DM, Bretscher A, Musser JM. Insight into the molecular basis of pathogen abundance: group A Streptococcus inhibitor of complement inhibits bacterial adherence and internalization into human cells. Proceedings of the National Academy of Sciences of the United States of America. 99: 7646-51. PMID 12032337 DOI: 10.1073/Pnas.112039899 |
0.367 |
|
| 2002 |
Ingraffea J, Reczek D, Bretscher A. Distinct cell type-specific expression of scaffolding proteins EBP50 and E3KARP: EBP50 is generally expressed with ezrin in specific epithelia, whereas E3KARP is not European Journal of Cell Biology. 81: 61-68. PMID 11893083 DOI: 10.1078/0171-9335-00218 |
0.425 |
|
| 2002 |
Evangelista M, Pruyne D, Amberg DC, Boone C, Bretscher A. Formins direct Arp2/3-independent actin filament assembly to polarize cell growth in yeast Nature Cell Biology. 4: 260-269. PMID 11875440 DOI: 10.1038/ncb770 |
0.766 |
|
| 2002 |
Schott DH, Collins RN, Bretscher A. Secretory vesicle transport velocity in living cells depends on the myosin-V lever arm length Journal of Cell Biology. 156: 35-39. PMID 11781333 DOI: 10.1083/Jcb.200110086 |
0.809 |
|
| 2001 |
Ho J, Bretscher A. Ras regulates the polarity of the yeast actin cytoskeleton through the stress response pathway Molecular Biology of the Cell. 12: 1541-1555. PMID 11408567 DOI: 10.1091/Mbc.12.6.1541 |
0.796 |
|
| 2001 |
Reczek D, Bretscher A. Identification of EPI64, a TBC/rabGAP domain-containing microvillar protein that binds to the first PDZ domain of EBP50 and E3KARP Journal of Cell Biology. 153: 191-205. PMID 11285285 DOI: 10.1083/Jcb.153.1.191 |
0.494 |
|
| 2001 |
Bretscher A. The cytoskeleton: from regulation to function. Conference: the 15th Meeting of the European Cytoskeleton Forum. Embo Reports. 1: 473-6. PMID 11263488 DOI: 10.1093/Embo-Reports/Kvd123 |
0.373 |
|
| 2001 |
Melendez-Vasquez CV, Rios JC, Zanazzi G, Lambert S, Bretscher A, Salzer JL. Nodes of Ranvier form in association with ezrin-radixin-moesin (ERM)-positive Schwann cell processes. Proceedings of the National Academy of Sciences of the United States of America. 98: 1235-40. PMID 11158623 DOI: 10.1073/Pnas.98.3.1235 |
0.358 |
|
| 2001 |
Nguyen R, Reczek D, Bretscher A. Hierarchy of Merlin and Ezrin N- and C-terminal Domain Interactions in Homo- and Heterotypic Associations and their Relationship to Binding of Scaffolding Proteins EBP50 and E3KARP Journal of Biological Chemistry. 276: 7621-7629. PMID 11106646 DOI: 10.1074/Jbc.M006708200 |
0.805 |
|
| 2000 |
Bretscher A, Chambers D, Nguyen R, Reczek D. ERM-Merlin and EBP50 protein families in plasma membrane organization and function Annual Review of Cell and Developmental Biology. 16: 113-143. PMID 11031232 DOI: 10.1146/Annurev.Cellbio.16.1.113 |
0.834 |
|
| 2000 |
Yin H, Pruyne D, Huffaker TC, Bretscher A. Myosin V orientates the mitotic spindle in yeast Nature. 406: 1013-1015. PMID 10984058 DOI: 10.1038/35023024 |
0.795 |
|
| 2000 |
Pearson MA, Reczek D, Bretscher A, Karplus PA. Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domain Cell. 101: 259-270. PMID 10847681 DOI: 10.1016/S0092-8674(00)80836-3 |
0.684 |
|
| 2000 |
Berryman M, Bretscher A. Identification of a novel member of the chloride intracellular channel gene family (CLIC5) that associates with the actin cytoskeleton of placental microvilli Molecular Biology of the Cell. 11: 1509-1521. PMID 10793131 DOI: 10.1091/Mbc.11.5.1509 |
0.76 |
|
| 2000 |
Pruyne D, Bretscher A. Polarization of cell growth in yeast. II. The role of the cortical actin cytoskeleton Journal of Cell Science. 113: 571-585. PMID 10652251 |
0.344 |
|
| 1999 |
Schott D, Ho J, Pruyne D, Bretscher A. The COOH-terminal domain of Myo2p, a yeast myosin V, has a direct role in secretory vesicle targeting Journal of Cell Biology. 147: 791-807. PMID 10562281 DOI: 10.1083/Jcb.147.4.791 |
0.81 |
|
| 1999 |
Cao TT, Deacon HW, Reczek D, Bretscher A, von Zastrow M. A kinase-regulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptor. Nature. 401: 286-90. PMID 10499588 DOI: 10.1038/45816 |
0.416 |
|
| 1999 |
Bretscher A. Regulation of cortical structure by the ezrin-radixin-moesin protein family Current Opinion in Cell Biology. 11: 109-116. PMID 10047517 DOI: 10.1016/S0955-0674(99)80013-1 |
0.503 |
|
| 1999 |
Shcherbina A, Bretscher A, Kenney DM, Remold-O'Donnell E. Moesin, the major ERM protein of lymphocytes and platelets, differs from ezrin in its insensitivity to calpain Febs Letters. 443: 31-36. PMID 9928947 DOI: 10.1016/S0014-5793(98)01674-3 |
0.388 |
|
| 1999 |
Shcherbina A, Kenney DM, Bretscher A, Remold-O’Donnell E. Dynamic Association of Moesin With the Membrane Skeleton of Thrombin-Activated Platelets Blood. 93: 2128-2129. DOI: 10.1182/Blood.V93.6.2128.406A41A_2128_2129 |
0.362 |
|
| 1998 |
Simons PC, Pietromonaco SF, Reczek D, Bretscher A, Elias L. C-terminal threonine phosphorylation activates ERM proteins to link the cell's cortical lipid bilayer to the cytoskeleton. Biochemical and Biophysical Research Communications. 253: 561-5. PMID 9918767 DOI: 10.1006/Bbrc.1998.9823 |
0.523 |
|
| 1998 |
Pruyne DW, Schott DH, Bretscher A. Tropomyosin-containing actin cables direct the Myo2p-dependent polarized delivery of secretory vesicles in budding yeast Journal of Cell Biology. 143: 1931-1945. PMID 9864365 DOI: 10.1083/Jcb.143.7.1931 |
0.815 |
|
| 1998 |
Gorham DA, Bretscher A, Carey HV. Hibernation Induces Expression of Moesin in Intestinal Epithelial Cells Cryobiology. 37: 146-154. PMID 9769165 DOI: 10.1006/Cryo.1998.2118 |
0.389 |
|
| 1998 |
Chishti AH, Kim AC, Marfatia SM, Lutchman M, Hanspal M, Jindal H, Liu SC, Low PS, Rouleau GA, Mohandas N, Chasis JA, Conboy JG, Gascard P, Takakuwa Y, Huang SC, ... ... Bretscher A, et al. The FERM domain: a unique module involved in the linkage of cytoplasmic proteins to the membrane. Trends in Biochemical Sciences. 23: 281-2. PMID 9757824 DOI: 10.1016/S0968-0004(98)01237-7 |
0.439 |
|
| 1998 |
Short DB, Trotter KW, Reczek D, Kreda SM, Bretscher A, Boucher RC, Stutts MJ, Milgram SL. An apical PDZ protein anchors the cystic fibrosis transmembrane conductance regulator to the cytoskeleton. The Journal of Biological Chemistry. 273: 19797-801. PMID 9677412 DOI: 10.1074/Jbc.273.31.19797 |
0.459 |
|
| 1998 |
Reczek D, Bretscher A. The carboxyl-terminal region of EBP50 binds to a site in the amino- terminal domain of ezrin that is masked in the dormant molecule Journal of Biological Chemistry. 273: 18452-18458. PMID 9660814 DOI: 10.1074/Jbc.273.29.18452 |
0.437 |
|
| 1997 |
Bretscher A, Reczek D, Berryman M. Ezrin: A protein requiring conformational activation to link microfilaments to the plasma membrane in the assembly of cell surface structures Journal of Cell Science. 110: 3011-3018. PMID 9365271 |
0.42 |
|
| 1997 |
Reczek D, Berryman M, Bretscher A. Identification of EPB50: A PDZ-containing phosphoprotein that associates with members of the ezrin-radixin-moesin family Journal of Cell Biology. 139: 169-179. PMID 9314537 DOI: 10.1083/Jcb.139.1.169 |
0.803 |
|
| 1995 |
Bretscher A, Gary R, Berryman M. Soluble ezrin purified from placenta exists as stable monomers and elongated dimers with masked C-terminal ezrin-radixin-moesin association domains Biochemistry. 34: 16830-16837. PMID 8527459 DOI: 10.1021/Bi00051A034 |
0.802 |
|
| 1995 |
Berryman M, Gary R, Bretscher A. Ezrin oligomers are major cytoskeletal components of placental microvilli: A proposal for their involvement in cortical morphogenesis Journal of Cell Biology. 131: 1231-1242. PMID 8522586 DOI: 10.1083/Jcb.131.5.1231 |
0.825 |
|
| 1995 |
Drees B, Brown C, Barrell BG, Bretscher A. Tropomyosin is essential in yeast, yet the TPM1 and TPM2 products perform distinct functions Journal of Cell Biology. 128: 383-392. PMID 7844152 DOI: 10.1083/Jcb.128.3.383 |
0.422 |
|
| 1995 |
Harsay E, Bretscher A. Parallel secretory pathways to the cell surface in yeast Journal of Cell Biology. 131: 297-310. PMID 7593160 DOI: 10.1083/Jcb.131.2.297 |
0.346 |
|
| 1995 |
Gary R, Bretscher A. Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding site Molecular Biology of the Cell. 6: 1061-1075. PMID 7579708 DOI: 10.1091/Mbc.6.8.1061 |
0.771 |
|
| 1995 |
Wang T, Bretscher A. The rho-GAP encoded by BEM2 regulates cytoskeletal structure in budding yeast Molecular Biology of the Cell. 6: 1011-1024. PMID 7579704 DOI: 10.1091/Mbc.6.8.1011 |
0.405 |
|
| 1994 |
Bretscher A. Microfilaments and membranes. Current Opinion in Cell Biology. 5: 653-60. PMID 8257607 DOI: 10.1016/0955-0674(93)90136-E |
0.505 |
|
| 1994 |
Bretscher A, Drees B, Harsay E, Schott D, Wang T. What are the basic functions of microfilaments? Insights from studies in budding yeast Journal of Cell Biology. 126: 821-825. PMID 8051208 DOI: 10.1083/Jcb.126.4.821 |
0.784 |
|
| 1994 |
Footer M, Bretscher A. Brush border myosin-I microinjected Into cultured cells is targeted to actin-containing surface structures Journal of Cell Science. 107: 1623-1631. PMID 7962202 |
0.373 |
|
| 1993 |
Franck Z, Gary R, Bretscher A. Moesin, like ezrin, colocalizes with actin in the cortical cytoskeleton in cultured cells, but its expression is more variable Journal of Cell Science. 105: 219-231. PMID 8360275 |
0.388 |
|
| 1993 |
Gary R, Bretscher A. Heterotypic and homotypic associations between ezrin and moesin, two putative membrane-cytoskeletal linking proteins Proceedings of the National Academy of Sciences of the United States of America. 90: 10846-10850. PMID 8248180 DOI: 10.1073/Pnas.90.22.10846 |
0.787 |
|
| 1993 |
Berryman M, Franck Z, Bretscher A. Ezrin is concentrated in the apical microvilli of a wide variety of epithelial cells whereas moesin is found primarily in endothelial cells Journal of Cell Science. 105: 1025-1043. PMID 8227193 |
0.36 |
|
| 1992 |
Bretscher A. Microfilament structure and function in the cortical cytoskeleton. Annual Review of Cell Biology. 7: 337-74. PMID 1839710 DOI: 10.1146/Annurev.Cb.07.110191.002005 |
0.409 |
|
| 1992 |
Liu H, Bretscher A. Characterization of TPM1 disrupted yeast cells indicates an involvement of tropomyosin in directed vesicular transport. The Journal of Cell Biology. 118: 285-99. PMID 1629236 DOI: 10.1083/Jcb.118.2.285 |
0.584 |
|
| 1992 |
Nefsky B, Bretscher A. Yeast actin is relatively well behaved. European Journal of Biochemistry. 206: 949-55. PMID 1606973 DOI: 10.1111/J.1432-1033.1992.Tb17005.X |
0.438 |
|
| 1992 |
Ye RR, Bretscher A. Identification and molecular characterization of the calmodulin-binding subunit gene (CMP1) of protein phosphatase 2B from Saccharomyces cerevisiae - An α-factor inducible gene European Journal of Biochemistry. 204: 713-723. PMID 1311678 DOI: 10.1111/J.1432-1033.1992.Tb16686.X |
0.382 |
|
| 1992 |
Liu H, Bretscher A. Characterization of TPM1 disrupted yeast cells indicates an involvement of tropomyosin in directed vesicular transport Trends in Cell Biology. 2: 291. DOI: 10.1016/0962-8924(92)90112-Z |
0.544 |
|
| 1991 |
Huffaker TC, Bretscher AP. Cloning and analyzing genes encoding cytoskeletal proteins in yeast Saccharomyces cerevisiae. Methods in Enzymology. 196: 355-68. PMID 2034130 DOI: 10.1016/0076-6879(91)96032-M |
0.371 |
|
| 1991 |
Hanzel D, Reggio H, Bretscher A, Forte JG, Mangeat P. The secretion-stimulated 80K phosphoprotein of parietal cells is ezrin, and has properties of a membrane cytoskeletal linker in the induced apical microvilli. The Embo Journal. 10: 2363-73. PMID 1831124 DOI: 10.1002/J.1460-2075.1991.Tb07775.X |
0.357 |
|
| 1991 |
Bretscher A. Molecular aspects of microfilament structure and assembly Current Opinion in Structural Biology. 1: 281-287. DOI: 10.1016/0959-440X(91)90074-4 |
0.462 |
|
| 1990 |
Franck Z, Footer M, Bretscher A. Microinjection of villin into cultured cells induces rapid and long-lasting changes in cell morphology but does not inhibit cytokinesis, cell motility, or membrane ruffling. Journal of Cell Biology. 111: 2475-2485. PMID 2277069 DOI: 10.1083/Jcb.111.6.2475 |
0.421 |
|
| 1990 |
Coluccio LM, Bretscher A. Mapping of the microvillar 110K-calmodulin complex (brush border myosin I). Identification of fragments containing the catalytic and F-actin-binding sites and demonstration of a calcium ion dependent conformational change. Biochemistry. 29: 11089-94. PMID 2271696 DOI: 10.1021/Bi00502A011 |
0.735 |
|
| 1989 |
Coluccio LM, Bretscher A. Reassociation of microvillar core proteins: making a microvillar core in vitro. The Journal of Cell Biology. 108: 495-502. PMID 2918023 DOI: 10.1083/Jcb.108.2.495 |
0.726 |
|
| 1989 |
Tilney MS, Tilney LG, Stephens RE, Merte C, Drenckhahn D, Cotanche DA, Bretscher A. Preliminary biochemical characterization of the stereocilia and cuticular plate of hair cells of the chick cochlea. The Journal of Cell Biology. 109: 1711-23. PMID 2677026 DOI: 10.1083/jcb.109.4.1711 |
0.622 |
|
| 1989 |
Liu HP, Bretscher A. Disruption of the single tropomyosin gene in yeast results in the disappearance of actin cables from the cytoskeleton. Cell. 57: 233-42. PMID 2649250 DOI: 10.1016/0092-8674(89)90961-6 |
0.613 |
|
| 1989 |
Bretscher A. Rapid phosphorylation and reorganization of ezrin and spectrin accompany morphological changes induced in A-431 cells by epidermal growth factor. Journal of Cell Biology. 108: 921-930. PMID 2646308 DOI: 10.1083/Jcb.108.3.921 |
0.442 |
|
| 1989 |
Nefsky B, Bretscher A. Preparation of immobilized monomeric actin and its use in the isolation of protease-free and ribonuclease-free pancreatic deoxyribonuclease I. European Journal of Biochemistry. 179: 215-9. PMID 2645136 DOI: 10.1111/J.1432-1033.1989.Tb14543.X |
0.433 |
|
| 1989 |
Liu HP, Bretscher A. Purification of tropomyosin from Saccharomyces cerevisiae and identification of related proteins in Schizosaccharomyces and Physarum. Proceedings of the National Academy of Sciences of the United States of America. 86: 90-3. PMID 2643110 DOI: 10.1073/Pnas.86.1.90 |
0.59 |
|
| 1988 |
Coluccio LM, Bretscher A. Mapping of the microvillar 110K-calmodulin complex: calmodulin-associated or -free fragments of the 110-kD polypeptide bind F-actin and retain ATPase activity. The Journal of Cell Biology. 106: 367-73. PMID 2963011 DOI: 10.1083/Jcb.106.2.367 |
0.725 |
|
| 1987 |
Bretscher A. Purification of the intestinal microvillus cytoskeletal proteins villin, fimbrin, and ezrin. Methods in Enzymology. 134: 24-37. PMID 3821564 DOI: 10.1016/0076-6879(86)34072-2 |
0.339 |
|
| 1987 |
Krizek J, Coluccio LM, Bretscher A. ATPase activity of the microvillar 110 kDa polypeptide-calmodulin complex is activated in Mg2+ and inhibited in K+-EDTA by F-actin. Febs Letters. 225: 269-72. PMID 2961614 DOI: 10.1016/0014-5793(87)81172-9 |
0.692 |
|
| 1987 |
Coluccio LM, Bretscher A. Calcium-regulated cooperative binding of the microvillar 110K-calmodulin complex to F-actin: formation of decorated filaments. The Journal of Cell Biology. 105: 325-33. PMID 2956267 DOI: 10.1083/Jcb.105.1.325 |
0.692 |
|
| 1986 |
Bretscher A. Thin filament regulatory proteins of smooth- and non-muscle cells. Nature. 321: 726-7. PMID 3713859 DOI: 10.1038/321726B0 |
0.348 |
|
| 1986 |
Gould KL, Cooper JA, Bretscher A, Hunter T. The protein-tyrosine kinase substrate, p81, is homologous to a chicken microvillar core protein Journal of Cell Biology. 102: 660-669. PMID 2418035 DOI: 10.1083/Jcb.102.2.660 |
0.325 |
|
| 1985 |
Verner K, Bretscher A. Microvillus 110K-calmodulin: effects of nucleotides on isolated cytoskeletons and the interaction of the purified complex with F-actin Journal of Cell Biology. 100: 1455-1465. PMID 3157690 DOI: 10.1083/Jcb.100.5.1455 |
0.317 |
|
| 1985 |
Bretscher A, Lynch W. Identification and localization of immunoreactive forms of caldesmon in smooth and nonmuscle cells: a comparison with the distributions of tropomyosin and alpha-actinin. The Journal of Cell Biology. 100: 1656-63. PMID 2985624 DOI: 10.1083/Jcb.100.5.1656 |
0.392 |
|
| 1982 |
Bretscher A. Fimbrin is a cytoskeletal protein that crosslinks F-actin in vitro. Proceedings of the National Academy of Sciences of the United States of America. 78: 6849-53. PMID 6947259 DOI: 10.1073/Pnas.78.11.6849 |
0.446 |
|
| 1982 |
Flock A, Bretscher A, Weber K. Immunohistochemical localization of several cytoskeletal proteins in inner ear sensory and supporting cells. Hearing Research. 7: 75-89. PMID 6178719 DOI: 10.1016/0378-5955(82)90082-X |
0.581 |
|
| 1981 |
Bretscher A, Osborn M, Wehland J, Weber K. Villin associates with specific microfilamentous structures as seen by immunofluorescence microscopy on tissue sections and cells microinjected with villin. Experimental Cell Research. 135: 213-9. PMID 7026267 DOI: 10.1016/0014-4827(81)90313-X |
0.542 |
|
| 1981 |
Glenney JR, Bretscher A, Weber K. Calcium control of the intestinal microvillus cytoskeleton: its implications for the regulation of microfilament organizations. Proceedings of the National Academy of Sciences of the United States of America. 77: 6458-62. PMID 6935660 DOI: 10.1073/Pnas.77.11.6458 |
0.499 |
|
| 1980 |
Bruder G, Bretscher A, Franke WW, Jarasch ED. Plasma membranes from intestinal microvilli and erythrocytes contain cytochromes b5 and P-420 Biochimica Et Biophysica Acta. 600: 739-755. PMID 7407143 DOI: 10.1016/0005-2736(80)90477-0 |
0.316 |
|
| 1980 |
Bretscher A, Weber K. Fimbrin, a new microfilament-associated protein present in microvilli and other cell surface structures. The Journal of Cell Biology. 86: 335-40. PMID 6998986 DOI: 10.1083/Jcb.86.1.335 |
0.55 |
|
| 1980 |
Bretscher A, Weber K. Villin is a major protein of the microvillus cytoskeleton which binds both G and F actin in a calcium-dependent manner. Cell. 20: 839-47. PMID 6893424 DOI: 10.1016/0092-8674(80)90330-X |
0.551 |
|
| 1979 |
Bretscher A, Weber K. Purification of microvilli and an analysis of the protein components of the microfilament core bundle. Experimental Cell Research. 116: 397-407. PMID 568557 DOI: 10.1016/0014-4827(78)90463-9 |
0.577 |
|
| 1979 |
Bretscher A, Weber K. Localization of actin and microfilament-associated proteins in the microvilli and terminal web of the intestinal brush border by immunofluorescence microscopy. The Journal of Cell Biology. 79: 839-45. PMID 365871 DOI: 10.1083/Jcb.79.3.839 |
0.531 |
|
| 1979 |
Bretscher A, Weber K. Villin: the major microfilament-associated protein of the intestinal microvillus. Proceedings of the National Academy of Sciences of the United States of America. 76: 2321-5. PMID 287075 DOI: 10.1073/Pnas.76.5.2321 |
0.553 |
|
| 1979 |
Bretscher A, Vandekerckhove J, Weber K. alpha-Actinins from chicken skeletal muscle and smooth muscle show considerable chemical and immunological differences. European Journal of Biochemistry. 100: 237-43. PMID 90613 DOI: 10.1111/J.1432-1033.1979.Tb02054.X |
0.42 |
|
| 1978 |
Bretscher A, Weber K. Tropomyosin from bovine brain contains two polypeptide chains of slightly different molecular weights. Febs Letters. 85: 145-8. PMID 620785 DOI: 10.1016/0014-5793(78)81267-8 |
0.403 |
|
| 1976 |
Bretscher AP, Baumberg S. Divergent transcription of the argECBH cluster of escherichia coli k12. Mutations which alter the control of enzyme synthesis. Journal of Molecular Biology. 102: 205-20. PMID 775103 DOI: 10.1016/S0022-2836(76)80049-6 |
0.584 |
|
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