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Alex J. Walsh - Publications

Affiliations: 
2010-2015 Biomedical Engineering Vanderbilt University, Nashville, TN 
 2019- Biomedical Engineering Texas A & M University, College Station, TX, United States 
Website:
https://qoil.engr.tamu.edu/
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41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Hu L, Wang N, Bryant JD, Liu L, Xie L, West AP, Walsh AJ. Label-free spatially maintained measurements of metabolic phenotypes in cells. Frontiers in Bioengineering and Biotechnology. 11: 1293268. PMID 38090715 DOI: 10.3389/fbioe.2023.1293268  0.774
2023 Sharma D, Sharma A, Hu L, Chen TA, Voon S, Bayless KJ, Goldman J, Walsh AJ, Zhao F. Perfusability and immunogenicity of implantable pre-vascularized tissues recapitulating features of native capillary network. Bioactive Materials. 30: 184-199. PMID 37589031 DOI: 10.1016/j.bioactmat.2023.07.023  0.692
2023 Hu L, Ter Hofstede B, Sharma D, Zhao F, Walsh AJ. Comparison of phasor analysis and biexponential decay curve fitting of autofluorescence lifetime imaging data for machine learning prediction of cellular phenotypes. Frontiers in Bioinformatics. 3: 1210157. PMID 37455808 DOI: 10.3389/fbinf.2023.1210157  0.745
2023 Yu W, Chen Y, Putluri N, Osman A, Coarfa C, Putluri V, Kamal AHM, Asmussen JK, Katsonis P, Myers JN, Lai SY, Lu W, Stephan CC, Powell RT, Johnson FM, ... ... Walsh AJ, et al. Evolution of cisplatin resistance through coordinated metabolic reprogramming of the cellular reductive state. British Journal of Cancer. PMID 37012319 DOI: 10.1038/s41416-023-02253-7  0.709
2023 Wang N, Hu L, Walsh AJ. POSEA: A novel algorithm to evaluate the performance of multi-object instance image segmentation. Plos One. 18: e0283692. PMID 36989326 DOI: 10.1371/journal.pone.0283692  0.722
2023 Benavides OR, Gibbs HC, White BP, Kaunas R, Gregory CA, Walsh AJ, Maitland KC. Volumetric imaging of human mesenchymal stem cells (hMSCs) for non-destructive quantification of 3D cell culture growth. Plos One. 18: e0282298. PMID 36976801 DOI: 10.1371/journal.pone.0282298  0.773
2023 Schmitz RL, Tweed KE, Rehani P, Samimi K, Riendeau J, Jones I, Maly EM, Guzman EC, Forsberg MH, Shahi A, Capitini CM, Walsh AJ, Skala MC. Autofluorescence lifetime imaging classifies human lymphocyte activation and subtype. Biorxiv : the Preprint Server For Biology. PMID 36747690 DOI: 10.1101/2023.01.23.525260  0.587
2022 Hu L, Morganti S, Nguyen U, Benavides OR, Walsh AJ. Label-free optical imaging of cell function and collagen structure for cell-based therapies. Current Opinion in Biomedical Engineering. 25. PMID 36642995 DOI: 10.1016/j.cobme.2022.100433  0.748
2022 Liu L, Zhou Y, Liu Z, Li J, Hu L, He L, Gao G, Kidd B, Walsh A, Jiang R, Wu C, Zhang K, Xie L. Osr1 regulates macrophage-mediated liver inflammation in non-alcoholic fatty liver disease progression. Cellular and Molecular Gastroenterology and Hepatology. PMID 36581078 DOI: 10.1016/j.jcmgh.2022.12.010  0.675
2022 Miskolci V, Tweed KE, Lasarev MR, Britt EC, Walsh AJ, Zimmerman LJ, McDougal CE, Cronan MR, Fan J, Sauer JD, Skala MC, Huttenlocher A. In vivo fluorescence lifetime imaging of macrophage intracellular metabolism during wound responses in zebrafish. Elife. 11. PMID 35200139 DOI: 10.7554/eLife.66080  0.574
2022 Cardona EN, Walsh AJ. Identification of rare cell populations in autofluorescence lifetime image data. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 101: 497-506. PMID 35038211 DOI: 10.1002/cyto.a.24534  0.399
2021 Theodossiou A, Hu L, Wang N, Nguyen U, Walsh AJ. Autofluorescence Imaging to Evaluate Cellular Metabolism. Journal of Visualized Experiments : Jove. PMID 34842243 DOI: 10.3791/63282  0.768
2021 Schmitz R, Tweed K, Walsh C, Walsh AJ, Skala MC. Extracellular pH affects the fluorescence lifetimes of metabolic co-factors. Journal of Biomedical Optics. 26. PMID 34032035 DOI: 10.1117/1.JBO.26.5.056502  0.551
2021 Lee W, Kingstad-Bakke B, Paulson B, Larsen A, Overmyer K, Marinaik CB, Dulli K, Toy R, Vogel G, Mueller KP, Tweed K, Walsh AJ, Russell J, Saha K, Reyes L, et al. Carbomer-based adjuvant elicits CD8 T-cell immunity by inducing a distinct metabolic state in cross-presenting dendritic cells. Plos Pathogens. 17: e1009168. PMID 33444400 DOI: 10.1371/journal.ppat.1009168  0.515
2020 Hu L, Wang N, Cardona E, Walsh AJ. Fluorescence intensity and lifetime redox ratios detect metabolic perturbations in T cells. Biomedical Optics Express. 11: 5674-5688. PMID 33149978 DOI: 10.1364/BOE.401935  0.755
2020 Walsh AJ, Mueller KP, Tweed K, Jones I, Walsh CM, Piscopo NJ, Niemi NM, Pagliarini DJ, Saha K, Skala MC. Classification of T-cell activation via autofluorescence lifetime imaging. Nature Biomedical Engineering. PMID 32719514 DOI: 10.1038/S41551-020-0592-Z  0.534
2019 Wang ZJ, Walsh AJ, Skala MC, Gitter A. Classifying T cell activity in autofluorescence intensity images with convolutional neural networks. Journal of Biophotonics. PMID 31661592 DOI: 10.1002/Jbio.201960050  0.586
2019 Walsh AJ, Sharick JT, Skala MC. Imaging intratumoral metabolic heterogeneity. Nature Biomedical Engineering. 3: 333-334. PMID 31073174 DOI: 10.1038/S41551-019-0398-Z  0.753
2019 Walsh AJ, Cook RS, Sanders ME, Arteaga CL, Skala MC. Author Correction: Drug response in organoids generated from frozen primary tumor tissues. Scientific Reports. 9: 6517. PMID 31019196 DOI: 10.1038/S41598-019-42133-W  0.479
2018 Zhang Q, Jeppesen DK, Higginbotham JN, Demory Beckler M, Poulin EJ, Walsh AJ, Skala MC, McKinley ET, Manning HC, Hight MR, Schulte ML, Watt KR, Ayers GD, Wolf MM, Andrejeva G, et al. Mutant KRAS Exosomes Alter the Metabolic State of Recipient Colonic Epithelial Cells. Cellular and Molecular Gastroenterology and Hepatology. 5: 627-629.e6. PMID 29930982 DOI: 10.1016/J.Jcmgh.2018.01.013  0.53
2017 Walsh AJ, Cook RS, Skala MC. Functional Optical Imaging of Primary Human Tumor Organoids for Personalized Drug Screens. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 28588148 DOI: 10.2967/Jnumed.117.192534  0.556
2017 Heaster TM, Walsh AJ, Zhao Y, Hiebert SW, Skala MC. Autofluorescence imaging identifies tumor cell-cycle status on a single-cell level. Journal of Biophotonics. PMID 28485124 DOI: 10.1002/Jbio.201600276  0.8
2016 Walsh AJ, Sharick JT, Skala MC, Beier HT. Temporal binning of time-correlated single photon counting data improves exponential decay fits and imaging speed. Biomedical Optics Express. 7: 1385-99. PMID 27446663 DOI: 10.1364/Boe.7.001385  0.754
2016 Walsh AJ, Cook RS, Sanders ME, Arteaga CL, Skala MC. Drug response in organoids generated from frozen primary tumor tissues. Scientific Reports. 6: 18889. PMID 26738962 DOI: 10.1038/Srep18889  0.537
2015 Shah AT, Diggins KE, Walsh AJ, Irish JM, Skala MC. In Vivo Autofluorescence Imaging of Tumor Heterogeneity in Response to Treatment. Neoplasia (New York, N.Y.). 17: 862-70. PMID 26696368 DOI: 10.1016/J.Neo.2015.11.006  0.761
2015 Walsh AJ, Castellanos JA, Nagathihalli NS, Merchant NB, Skala MC. Optical Imaging of Drug-Induced Metabolism Changes in Murine and Human Pancreatic Cancer Organoids Reveals Heterogeneous Drug Response. Pancreas. PMID 26495796 DOI: 10.1097/Mpa.0000000000000543  0.568
2015 Campos-Delgado DU, Navarro OG, Arce-Santana ER, Walsh AJ, Skala MC, Jo JA. Deconvolution of fluorescence lifetime imaging microscopy by a library of exponentials. Optics Express. 23: 23748-67. PMID 26368470 DOI: 10.1364/Oe.23.023748  0.562
2015 Nagathihalli NS, Castellanos JA, Shi C, Beesetty Y, Reyzer ML, Caprioli R, Chen X, Walsh AJ, Skala MC, Moses HL, Merchant NB. Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer. Gastroenterology. PMID 26255562 DOI: 10.1053/J.Gastro.2015.07.058  0.472
2015 Campos-Delgado DU, Gutierrez-Navarro O, Arce-Santana ER, Skala MC, Walsh AJ, Jo JA. Blind deconvolution estimation of fluorescence measurements through quadratic programming. Journal of Biomedical Optics. 20: 075010. PMID 26222960 DOI: 10.1117/1.Jbo.20.7.075010  0.519
2015 Walsh AJ, Skala MC. Optical metabolic imaging quantifies heterogeneous cell populations. Biomedical Optics Express. 6: 559-73. PMID 25780745 DOI: 10.1364/Boe.6.000559  0.649
2015 Walsh AJ, Cook RS, Lee JH, Arteaga CL, Skala MC. Collagen density and alignment in responsive and resistant trastuzumab-treated breast cancer xenografts. Journal of Biomedical Optics. 20: 26004. PMID 25700233 DOI: 10.1117/1.Jbo.20.2.026004  0.532
2015 Cannon TM, Shah AT, Walsh AJ, Skala MC. High-throughput measurements of the optical redox ratio using a commercial microplate reader. Journal of Biomedical Optics. 20: 010503. PMID 25634108 DOI: 10.1117/1.Jbo.20.1.010503  0.727
2014 Walsh AJ, Cook RS, Sanders ME, Aurisicchio L, Ciliberto G, Arteaga CL, Skala MC. Quantitative optical imaging of primary tumor organoid metabolism predicts drug response in breast cancer. Cancer Research. 74: 5184-94. PMID 25100563 DOI: 10.1158/0008-5472.Can-14-0663  0.611
2014 McCormack DR, Walsh AJ, Sit W, Arteaga CL, Chen J, Cook RS, Skala MC. In vivo hyperspectral imaging of microvessel response to trastuzumab treatment in breast cancer xenografts. Biomedical Optics Express. 5: 2247-61. PMID 25071962 DOI: 10.1364/Boe.5.002247  0.53
2014 Shah AT, Demory Beckler M, Walsh AJ, Jones WP, Pohlmann PR, Skala MC. Optical metabolic imaging of treatment response in human head and neck squamous cell carcinoma. Plos One. 9: e90746. PMID 24595244 DOI: 10.1371/Journal.Pone.0090746  0.728
2014 Venkateswaran A, Sekhar KR, Levic DS, Melville DB, Clark TA, Rybski WM, Walsh AJ, Skala MC, Crooks PA, Knapik EW, Freeman ML. The NADH oxidase ENOX1, a critical mediator of endothelial cell radiosensitization, is crucial for vascular development. Cancer Research. 74: 38-43. PMID 24247717 DOI: 10.1158/0008-5472.Can-13-1981  0.509
2013 Walsh AJ, Cook RS, Manning HC, Hicks DJ, Lafontant A, Arteaga CL, Skala MC. Optical metabolic imaging identifies glycolytic levels, subtypes, and early-treatment response in breast cancer. Cancer Research. 73: 6164-74. PMID 24130112 DOI: 10.1158/0008-5472.Can-13-0527  0.632
2013 Poole KM, Tucker-Schwartz JM, Sit WW, Walsh AJ, Duvall CL, Skala MC. Quantitative optical imaging of vascular response in vivo in a model of peripheral arterial disease. American Journal of Physiology. Heart and Circulatory Physiology. 305: H1168-80. PMID 23955718 DOI: 10.1152/Ajpheart.00362.2013  0.769
2013 Venkateswaran A, Friedman DB, Walsh AJ, Skala MC, Sasi S, Rachakonda G, Crooks PA, Freeman ML, Sekhar KR. The novel antiangiogenic VJ115 inhibits the NADH oxidase ENOX1 and cytoskeleton-remodeling proteins. Investigational New Drugs. 31: 535-44. PMID 23054211 DOI: 10.1007/S10637-012-9884-9  0.488
2012 Walsh AJ, Poole KM, Duvall CL, Skala MC. Ex vivo optical metabolic measurements from cultured tissue reflect in vivo tissue status. Journal of Biomedical Optics. 17: 116015. PMID 23117810 DOI: 10.1117/1.Jbo.17.11.116015  0.577
2012 Walsh A, Cook RS, Rexer B, Arteaga CL, Skala MC. Optical imaging of metabolism in HER2 overexpressing breast cancer cells. Biomedical Optics Express. 3: 75-85. PMID 22254170 DOI: 10.1364/Boe.3.000075  0.59
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