Alan R. Saltiel - Publications

Affiliations: 
University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
diabetes, receptors, signal transduction

253 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Gu L, Zhu Y, Watari K, Lee M, Liu J, Perez S, Thai M, Mayfield JE, Zhang B, Cunha E Rocha K, Li F, Kim LC, Jones AC, Wierzbicki IH, Liu X, ... ... Saltiel AR, et al. Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness. Cell Metabolism. PMID 37084733 DOI: 10.1016/j.cmet.2023.03.021  0.468
2021 Martins VF, LaBarge SA, Stanley A, Svensson K, Hung CW, Keinan O, Ciaraldi TP, Banoian D, Park JE, Ha C, Hetrick B, Meyer GA, Philp A, David LL, Henry RR, ... ... Saltiel AR, et al. p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes. Jci Insight. PMID 34813504 DOI: 10.1172/jci.insight.141344  0.435
2021 Keinan O, Valentine JM, Xiao H, Mahata SK, Reilly SM, Abu-Odeh M, Deluca JH, Dadpey B, Cho L, Pan A, Yu RT, Dai Y, Liddle C, Downes M, Evans RM, ... ... Saltiel AR, et al. Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes. Nature. PMID 34707293 DOI: 10.1038/s41586-021-04019-8  0.335
2021 Yong J, Parekh VS, Reilly SM, Nayak J, Chen Z, Lebeaupin C, Jang I, Zhang J, Prakash TP, Sun H, Murray S, Guo S, Ayala JE, Satin LS, Saltiel AR, et al. / depletion in β cells alleviates ER stress and corrects hepatic steatosis in mice. Science Translational Medicine. 13. PMID 34321322 DOI: 10.1126/scitranslmed.aba9796  0.316
2021 Roth J, Ashcroft FM, Wollheim CB, Kieffer TJ, Cherrington AD, Bergman RN, Taylor R, Najjar SM, Pedersen O, Ellingsgaard H, Holst JJ, Nauck MA, Kadowaki T, Czech MP, Corvera S, ... Saltiel AR, et al. Voices: Insulin and beyond. Cell Metabolism. 33: 692-699. PMID 33826910 DOI: 10.1016/j.cmet.2021.03.017  0.343
2021 Reilly SM, Abu-Odeh M, Ameka M, DeLuca JH, Naber MC, Dadpey B, Ebadat N, Gomez AV, Peng X, Poirier B, Walk E, Potthoff MJ, Saltiel AR. FGF21 is required for the metabolic benefits of IKKε/TBK1 inhibition. The Journal of Clinical Investigation. PMID 33822771 DOI: 10.1172/JCI145546  0.334
2021 Saltiel AR. Insulin signaling in health and disease. The Journal of Clinical Investigation. 131. PMID 33393497 DOI: 10.1172/JCI142241  0.506
2020 Zhao P, Saltiel AR. From Overnutrition to Liver Injury: AMP-Activated Protein Kinase in Nonalcoholic Fatty Liver Diseases. The Journal of Biological Chemistry. PMID 32651233 DOI: 10.1074/Jbc.Rev120.011356  0.346
2020 Zhao P, Sun X, Chaggan C, Liao Z, In Wong K, He F, Singh S, Loomba R, Karin M, Witztum JL, Saltiel AR. An AMPK-caspase-6 axis controls liver damage in nonalcoholic steatohepatitis. Science (New York, N.Y.). 367: 652-660. PMID 32029622 DOI: 10.1126/Science.Aay0542  0.302
2020 Wagner M, Skorobogatko Y, Pode-Shakked B, Powell CM, Alhaddad B, Seibt A, Barel O, Heimer G, Hoffmann C, Demmer LA, Perilla-Young Y, Remke M, Wieczorek D, Navaratnarajah T, Lichtner P, ... ... Saltiel AR, et al. Bi-allelic Variants in RALGAPA1 Cause Profound Neurodevelopmental Disability, Muscular Hypotonia, Infantile Spasms, and Feeding Abnormalities. American Journal of Human Genetics. PMID 32004447 DOI: 10.1016/J.Ajhg.2020.01.002  0.324
2019 Wang L, Mazagova M, Pan C, Yang S, Brandl K, Liu J, Reilly SM, Wang Y, Miao Z, Loomba R, Lu N, Guo Q, Liu J, Yu RT, Downes M, ... ... Saltiel AR, et al. YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity. Proceedings of the National Academy of Sciences of the United States of America. PMID 31289229 DOI: 10.1073/Pnas.1904360116  0.341
2019 GOMEZ AV, REILLY S, ODEH MA, WALK E, SALTIEL A. 2043-P: The Biphasic Antiobesogenic Effects of Amlexanox Diabetes. 68: 2043-P. DOI: 10.2337/Db19-2043-P  0.312
2018 Beyett TS, Gan X, Reilly SM, Gomez AV, Chang L, Tesmer JJG, Saltiel AR, Showalter HD. Design, synthesis, and biological activity of substituted 2-amino-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid derivatives as inhibitors of the inflammatory kinases TBK1 and IKKε for the treatment of obesity. Bioorganic & Medicinal Chemistry. PMID 30270002 DOI: 10.1016/J.Bmc.2018.09.020  0.425
2018 Skorobogatko Y, Dragan M, Cordon C, Reilly SM, Hung CW, Xia W, Zhao P, Wallace M, Lackey DE, Chen XW, Osborn O, Bogner-Strauss JG, Theodorescu D, Metallo CM, Olefsky JM, ... Saltiel AR, et al. RalA controls glucose homeostasis by regulating glucose uptake in brown fat. Proceedings of the National Academy of Sciences of the United States of America. PMID 29915037 DOI: 10.1073/Pnas.1801050115  0.679
2018 Ahmadian M, Liu S, Reilly SM, Hah N, Fan W, Yoshihara E, Jha P, De Magalhaes Filho CD, Jacinto S, Gomez AV, Dai Y, Yu RT, Liddle C, Atkins AR, Auwerx J, ... Saltiel AR, et al. ERRγ Preserves Brown Fat Innate Thermogenic Activity. Cell Reports. 22: 2849-2859. PMID 29539415 DOI: 10.1016/J.Celrep.2018.02.061  0.315
2018 Zhao P, Wong KI, Sun X, Reilly SM, Uhm M, Liao Z, Skorobogatko Y, Saltiel AR. TBK1 at the Crossroads of Inflammation and Energy Homeostasis in Adipose Tissue. Cell. 172: 731-743.e12. PMID 29425491 DOI: 10.1016/J.Cell.2018.01.007  0.443
2018 Beyett TS, Gan X, Reilly SM, Chang L, Gomez AV, Saltiel AR, Showalter HD, Tesmer JJG. Carboxylic Acid Derivatives of Amlexanox Display Enhanced Potency toward TBK1 and IKKepsilonand Reveal Mechanisms for Selective Inhibition. Molecular Pharmacology. 94: 1210-1219. DOI: 10.2210/Pdb6Boe/Pdb  0.359
2017 Cho CS, Park HW, Ho A, Semple IA, Kim B, Jang I, Park H, Reilly S, Saltiel AR, Lee JH. Lipotoxicity induces hepatic protein inclusions through TBK1-mediated p62/SQSTM1 phosphorylation. Hepatology (Baltimore, Md.). PMID 29251796 DOI: 10.1002/Hep.29742  0.361
2017 Ichikawa T, Kita M, Matsui TS, Nagasato AI, Araki T, Chiang SH, Sezaki T, Kimura Y, Ueda K, Deguchi S, Saltiel AR, Kioka N. Vinexin family (SORBS) proteins play different roles in stiffness-sensing and contractile force generation. Journal of Cell Science. PMID 28864765 DOI: 10.1242/Jcs.200691  0.563
2017 Reilly SM, Saltiel AR. Adapting to obesity with adipose tissue inflammation. Nature Reviews. Endocrinology. PMID 28799554 DOI: 10.1038/Nrendo.2017.90  0.325
2017 Oral EA, Reilly SM, Gomez AV, Meral R, Butz L, Ajluni N, Chenevert TL, Korytnaya E, Neidert AH, Hench R, Rus D, Horowitz JF, Poirier B, Zhao P, Lehmann K, ... ... Saltiel AR, et al. Inhibition of IKKɛ and TBK1 Improves Glucose Control in a Subset of Patients with Type 2 Diabetes. Cell Metabolism. 26: 157-170.e7. PMID 28683283 DOI: 10.1016/J.Cmet.2017.06.006  0.39
2017 Uhm M, Bazuine M, Zhao P, Chiang SH, Xiong T, Karunanithi S, Chang L, Saltiel AR. Phosphorylation of the exocyst protein Exo84 by TBK1 promotes insulin-stimulated GLUT4 trafficking. Science Signaling. 10. PMID 28325821 DOI: 10.1126/Scisignal.Aah5085  0.799
2017 Saltiel AR, Olefsky JM. Inflammatory mechanisms linking obesity and metabolic disease. The Journal of Clinical Investigation. 127: 1-4. PMID 28045402 DOI: 10.1172/Jci92035  0.302
2016 Ceperuelo-Mallafré V, Ejarque M, Serena C, Duran X, Montori-Grau M, Rodríguez MA, Yanes O, Núñez-Roa C, Roche K, Puthanveetil P, Garrido-Sánchez L, Saez E, Tinahones FJ, Garcia-Roves PM, Gómez-Foix AM, ... Saltiel AR, et al. Adipose tissue glycogen accumulation is associated with obesity-linked inflammation in humans. Molecular Metabolism. 5: 5-18. PMID 26844203 DOI: 10.1016/J.Molmet.2015.10.001  0.369
2016 Saltiel AR. Insulin Signaling in the Control of Glucose and Lipid Homeostasis. Handbook of Experimental Pharmacology. PMID 26721672 DOI: 10.1007/164_2015_14  0.434
2015 Baeza-Raja B, Sachs BD, Li P, Christian F, Vagena E, Davalos D, Le Moan N, Ryu JK, Sikorski SL, Chan JP, Scadeng M, Taylor SS, Houslay MD, Baillie GS, Saltiel AR, et al. p75 Neurotrophin Receptor Regulates Energy Balance in Obesity. Cell Reports. PMID 26748707 DOI: 10.1016/J.Celrep.2015.12.028  0.392
2015 Maillard I, Saltiel AR. Metabolism: Inflammation keeps old mice healthy. Nature. PMID 26580010 DOI: 10.1038/Nature15648  0.397
2015 Hochberg I, Harvey I, Tran QT, Stephenson EJ, Barkan AL, Saltiel A, Chandler WF, Bridges D. Gene expression changes in subcutaneous adipose tissue due to Cushing's disease. Journal of Molecular Endocrinology. PMID 26150553 DOI: 10.1530/Jme-15-0119  0.316
2015 Hochberg I, Tran QT, Barkan AL, Saltiel AR, Chandler WF, Bridges D. Gene Expression Signature in Adipose Tissue of Acromegaly Patients. Plos One. 10: e0129359. PMID 26087292 DOI: 10.1186/1471-2105-15-S10-P28  0.388
2015 Buchner DA, Charrier A, Srinivasan E, Wang L, Paulsen MT, Ljungman M, Bridges D, Saltiel AR. Zinc finger protein 407 (ZFP407) regulates insulin-stimulated glucose uptake and glucose transporter 4 (Glut4) mRNA. The Journal of Biological Chemistry. 290: 6376-86. PMID 25596527 DOI: 10.1074/Jbc.M114.623736  0.513
2015 Reilly SM, Ahmadian M, Zamarron BF, Chang L, Uhm M, Poirier B, Peng X, Krause DM, Korytnaya E, Neidert A, Liddle C, Yu RT, Lumeng CN, Oral EA, Downes M, ... ... Saltiel AR, et al. A subcutaneous adipose tissue-liver signalling axis controls hepatic gluconeogenesis. Nature Communications. 6: 6047. PMID 25581158 DOI: 10.1038/Ncomms7047  0.41
2015 Fang S, Suh JM, Reilly SM, Yu E, Osborn O, Lackey D, Yoshihara E, Perino A, Jacinto S, Lukasheva Y, Atkins AR, Khvat A, Schnabl B, Yu RT, Brenner DA, ... ... Saltiel AR, et al. Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance. Nature Medicine. 21: 159-65. PMID 25559344 DOI: 10.1038/Nm.3760  0.366
2015 Bridges D, Saltiel AR. Phosphoinositides: Key modulators of energy metabolism. Biochimica Et Biophysica Acta. 1851: 857-866. PMID 25463477 DOI: 10.1016/J.Bbalip.2014.11.008  0.443
2014 Karunanithi S, Xiong T, Uhm M, Leto D, Sun J, Chen XW, Saltiel AR. A Rab10:RalA G protein cascade regulates insulin-stimulated glucose uptake in adipocytes. Molecular Biology of the Cell. 25: 3059-69. PMID 25103239 DOI: 10.1091/Mbc.E14-06-1060  0.844
2014 Morrow AA, Alipour MA, Bridges D, Yao Z, Saltiel AR, Lee JM. The lipid kinase PI4KIIIβ is highly expressed in breast tumors and activates Akt in cooperation with Rab11a. Molecular Cancer Research : McR. 12: 1492-508. PMID 24962317 DOI: 10.1158/1541-7786.Mcr-13-0604  0.385
2014 Liu S, Xu R, Gerin I, Cawthorn WP, Macdougald OA, Chen XW, Saltiel AR, Koenig RJ, Xu B. SRA regulates adipogenesis by modulating p38/JNK phosphorylation and stimulating insulin receptor gene expression and downstream signaling. Plos One. 9: e95416. PMID 24743795 DOI: 10.1371/Journal.Pone.0095416  0.73
2014 Lu B, Bridges D, Yang Y, Fisher K, Cheng A, Chang L, Meng ZX, Lin JD, Downes M, Yu RT, Liddle C, Evans RM, Saltiel AR. Metabolic crosstalk: molecular links between glycogen and lipid metabolism in obesity. Diabetes. 63: 2935-48. PMID 24722244 DOI: 10.2337/Db13-1531  0.441
2014 Reilly SM, Saltiel AR. Obesity: A complex role for adipose tissue macrophages Nature Reviews Endocrinology. 10: 193-194. PMID 24492182 DOI: 10.1038/Nrendo.2014.12  0.381
2014 Jin N, Mao K, Jin Y, Tevzadze G, Kauffman EJ, Park S, Bridges D, Loewith R, Saltiel AR, Klionsky DJ, Weisman LS. Roles for PI(3,5)P2 in nutrient sensing through TORC1. Molecular Biology of the Cell. 25: 1171-85. PMID 24478451 DOI: 10.1091/Mbc.E14-01-0021  0.434
2014 Martin TD, Chen XW, Kaplan RE, Saltiel AR, Walker CL, Reiner DJ, Der CJ. Ral and Rheb GTPase activating proteins integrate mTOR and GTPase signaling in aging, autophagy, and tumor cell invasion. Molecular Cell. 53: 209-20. PMID 24389102 DOI: 10.1016/J.Molcel.2013.12.004  0.583
2014 Wang GX, Cho KW, Uhm M, Hu CR, Li S, Cozacov Z, Xu AE, Cheng JX, Saltiel AR, Lumeng CN, Lin JD. Otopetrin 1 protects mice from obesity-associated metabolic dysfunction through attenuating adipose tissue inflammation. Diabetes. 63: 1340-52. PMID 24379350 DOI: 10.2337/Db13-1139  0.373
2013 Mowers J, Uhm M, Reilly SM, Simon J, Leto D, Chiang SH, Chang L, Saltiel AR. Inflammation produces catecholamine resistance in obesity via activation of PDE3B by the protein kinases IKKε and TBK1. Elife. 2: e01119. PMID 24368730 DOI: 10.7554/Elife.01119  0.797
2013 Suzuki T, Bridges D, Nakada D, Skiniotis G, Morrison SJ, Lin JD, Saltiel AR, Inoki K. Inhibition of AMPK catabolic action by GSK3. Molecular Cell. 50: 407-19. PMID 23623684 DOI: 10.1016/J.Molcel.2013.03.022  0.438
2013 Reilly SM, Chiang SH, Decker SJ, Chang L, Uhm M, Larsen MJ, Rubin JR, Mowers J, White NM, Hochberg I, Downes M, Yu RT, Liddle C, Evans RM, Oh D, ... ... Saltiel AR, et al. An inhibitor of the protein kinases TBK1 and IKK-É› improves obesity-related metabolic dysfunctions in mice. Nature Medicine. 19: 313-21. PMID 23396211 DOI: 10.1038/Nm.3082  0.652
2013 Leto D, Uhm M, Williams A, Chen XW, Saltiel AR. Negative regulation of the RalGAP complex by 14-3-3. The Journal of Biological Chemistry. 288: 9272-83. PMID 23386617 DOI: 10.1074/Jbc.M112.426106  0.801
2013 Mowers J, Uhm M, Reilly SM, Simon J, Leto D, Chiang S, Chang L, Saltiel AR. Author response: Inflammation produces catecholamine resistance in obesity via activation of PDE3B by the protein kinases IKKε and TBK1 Elife. DOI: 10.7554/Elife.01119.013  0.785
2012 Bridges D, Saltiel AR. Phosphoinositides in insulin action and diabetes. Current Topics in Microbiology and Immunology. 362: 61-85. PMID 23086413 DOI: 10.1007/978-94-007-5025-8_3  0.497
2012 Zolov SN, Bridges D, Zhang Y, Lee WW, Riehle E, Verma R, Lenk GM, Converso-Baran K, Weide T, Albin RL, Saltiel AR, Meisler MH, Russell MW, Weisman LS. In vivo, Pikfyve generates PI(3,5)P2, which serves as both a signaling lipid and the major precursor for PI5P. Proceedings of the National Academy of Sciences of the United States of America. 109: 17472-7. PMID 23047693 DOI: 10.1073/Pnas.1203106109  0.351
2012 Bridges D, Chang L, Lodhi IJ, Clark NA, Saltiel AR. TC10 is regulated by caveolin in 3T3-L1 adipocytes. Plos One. 7: e42451. PMID 22900022 DOI: 10.1371/Journal.Pone.0042451  0.733
2012 Bridges D, Ma JT, Park S, Inoki K, Weisman LS, Saltiel AR. Phosphatidylinositol 3,5-bisphosphate plays a role in the activation and subcellular localization of mechanistic target of rapamycin 1. Molecular Biology of the Cell. 23: 2955-62. PMID 22696681 DOI: 10.1091/Mbc.E11-12-1034  0.408
2012 Saltiel AR. Insulin resistance in the defense against obesity Cell Metabolism. 15: 798-804. PMID 22682220 DOI: 10.1016/J.Cmet.2012.03.001  0.454
2012 Leto D, Saltiel AR. Regulation of glucose transport by insulin: traffic control of GLUT4. Nature Reviews. Molecular Cell Biology. 13: 383-96. PMID 22617471 DOI: 10.1038/Nrm3351  0.839
2012 Bridges D, Fisher K, Zolov SN, Xiong T, Inoki K, Weisman LS, Saltiel AR. Rab5 proteins regulate activation and localization of target of rapamycin complex 1. The Journal of Biological Chemistry. 287: 20913-21. PMID 22547071 DOI: 10.1074/Jbc.M111.334060  0.567
2012 Baeza-Raja B, Li P, Le Moan N, Sachs BD, Schachtrup C, Davalos D, Vagena E, Bridges D, Kim C, Saltiel AR, Olefsky JM, Akassoglou K. p75 neurotrophin receptor regulates glucose homeostasis and insulin sensitivity. Proceedings of the National Academy of Sciences of the United States of America. 109: 5838-43. PMID 22460790 DOI: 10.1073/Pnas.1103638109  0.53
2011 Li S, Chen XW, Yu L, Saltiel AR, Lin JD. Circadian metabolic regulation through crosstalk between casein kinase 1δ and transcriptional coactivator PGC-1α. Molecular Endocrinology (Baltimore, Md.). 25: 2084-93. PMID 22052997 DOI: 10.1210/Me.2011-1227  0.584
2011 Chen XW, Saltiel AR. Ral's engagement with the exocyst: breaking up is hard to do. Cell Cycle (Georgetown, Tex.). 10: 2299-304. PMID 21654196 DOI: 10.4161/Cc.10.14.16524  0.698
2011 Chen XW, Leto D, Xiao J, Goss J, Wang Q, Shavit JA, Xiong T, Yu G, Ginsburg D, Toomre D, Xu Z, Saltiel AR. Exocyst function is regulated by effector phosphorylation. Nature Cell Biology. 13: 580-8. PMID 21516108 DOI: 10.1038/Ncb2226  0.825
2011 Chen XW, Leto D, Xiong T, Yu G, Cheng A, Decker S, Saltiel AR. A Ral GAP complex links PI 3-kinase/Akt signaling to RalA activation in insulin action. Molecular Biology of the Cell. 22: 141-52. PMID 21148297 DOI: 10.1091/Mbc.E10-08-0665  0.844
2010 Saltiel AR. Fishing out a sensor for anti-inflammatory oils. Cell. 142: 672-4. PMID 20813253 DOI: 10.1016/J.Cell.2010.08.022  0.338
2010 PLOURDE R, D'ALARCAO M, SALTIEL AR. ChemInform Abstract: Synthesis and Characterization of an Insulin-Mimetic Disaccharide (I). Cheminform. 23: no-no. DOI: 10.1002/CHIN.199241239  0.371
2009 Westcott DJ, Delproposto JB, Geletka LM, Wang T, Singer K, Saltiel AR, Lumeng CN. MGL1 promotes adipose tissue inflammation and insulin resistance by regulating 7/4hi monocytes in obesity. The Journal of Experimental Medicine. 206: 3143-56. PMID 19995956 DOI: 10.1084/Jem.20091333  0.399
2009 Chiang SH, Bazuine M, Lumeng CN, Geletka LM, Mowers J, White NM, Ma JT, Zhou J, Qi N, Westcott D, Delproposto JB, Blackwell TS, Yull FE, Saltiel AR. The protein kinase IKKepsilon regulates energy balance in obese mice. Cell. 138: 961-75. PMID 19737522 DOI: 10.1016/J.Cell.2009.06.046  0.676
2009 Xiao J, Chen XW, Davies BA, Saltiel AR, Katzmann DJ, Xu Z. Structural basis of Ist1 function and Ist1-Did2 interaction in the multivesicular body pathway and cytokinesis. Molecular Biology of the Cell. 20: 3514-24. PMID 19477918 DOI: 10.1091/Mbc.E09-05-0403  0.554
2009 Cheng A, Zhang M, Okubo M, Omichi K, Saltiel AR. Distinct mutations in the glycogen debranching enzyme found in glycogen storage disease type III lead to impairment in diverse cellular functions Human Molecular Genetics. 18: 2045-2052. PMID 19299494 DOI: 10.1093/Hmg/Ddp128  0.314
2009 Cheng A, Saltiel AR. Von Gierke's disease adopts an orphan (and its partner) Science Signaling. 2: pe8. PMID 19224896 DOI: 10.1126/Scisignal.258Pe8  0.367
2009 Saltiel AR. Second messengers of insulin action. Trends in Endocrinology and Metabolism: Tem. 1: 158-63. PMID 18411111 DOI: 10.1016/1043-2760(90)90029-3  0.538
2009 Kayali A, Haruta T, Saltiel A, Olefsky J, Webster NJG. O-36: A possible role for phospholipase Cγ in insulin action? Experimental and Clinical Endocrinology & Diabetes. 104: 46-47. DOI: 10.1055/S-0029-1211527  0.427
2008 Lodhi IJ, Bridges D, Chiang SH, Zhang Y, Cheng A, Geletka LM, Weisman LS, Saltiel AR. Insulin stimulates phosphatidylinositol 3-phosphate production via the activation of Rab5. Molecular Biology of the Cell. 19: 2718-28. PMID 18434594 DOI: 10.1091/Mbc.E08-01-0105  0.822
2007 Cheng A, Zhang M, Gentry MS, Worby CA, Dixon JE, Saltiel AR. A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease. Genes & Development. 21: 2399-409. PMID 17908927 DOI: 10.1101/Gad.1553207  0.305
2007 Zhang M, Liu J, Cheng A, DeYoung SM, Saltiel AR. Identification of CAP as a costameric protein that interacts with filamin C Molecular Biology of the Cell. 18: 4731-4740. PMID 17898075 DOI: 10.1091/Mbc.E07-06-0628  0.352
2007 Chen XW, Leto D, Chiang SH, Wang Q, Saltiel AR. Activation of RalA is required for insulin-stimulated Glut4 trafficking to the plasma membrane via the exocyst and the motor protein Myo1c. Developmental Cell. 13: 391-404. PMID 17765682 DOI: 10.1016/J.Devcel.2007.07.007  0.838
2007 Lesniewski LA, Hosch SE, Neels JG, de Luca C, Pashmforoush M, Lumeng CN, Chiang SH, Scadeng M, Saltiel AR, Olefsky JM. Bone marrow-specific Cap gene deletion protects against high-fat diet-induced insulin resistance. Nature Medicine. 13: 455-62. PMID 17351624 DOI: 10.1038/Nm1550  0.694
2007 Lumeng CN, Bodzin JL, Saltiel AR. Obesity induces a phenotypic switch in adipose tissue macrophage polarization. The Journal of Clinical Investigation. 117: 175-84. PMID 17200717 DOI: 10.1172/Jci29881  0.364
2007 Chen XW, Saltiel AR. TIRFing out Studies on Glut4 Trafficking Developmental Cell. 12: 4-5. PMID 17199036 DOI: 10.1016/J.Devcel.2006.12.008  0.666
2007 Lumeng CN, Deyoung SM, Bodzin JL, Saltiel AR. Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity. Diabetes. 56: 16-23. PMID 17192460 DOI: 10.2337/Db06-1076  0.333
2007 Lodhi IJ, Chiang SH, Chang L, Vollenweider D, Watson RT, Inoue M, Pessin JE, Saltiel AR. Gapex-5, a Rab31 guanine nucleotide exchange factor that regulates Glut4 trafficking in adipocytes. Cell Metabolism. 5: 59-72. PMID 17189207 DOI: 10.1016/J.Cmet.2006.12.006  0.824
2007 Chang L, Chiang SH, Saltiel AR. TC10α is required for insulin-stimulated glucose uptake in adipocytes Endocrinology. 148: 27-33. PMID 17008399 DOI: 10.1210/En.2006-1167  0.729
2007 Lumeng CN, Deyoung SM, Saltiel AR. Macrophages block insulin action in adipocytes by altering expression of signaling and glucose transport proteins. American Journal of Physiology. Endocrinology and Metabolism. 292: E166-74. PMID 16926380 DOI: 10.1152/Ajpendo.00284.2006  0.518
2007 Watson RT, Saltiel AR, Pessin JE, Kanzaki M. Subcellular compartmentalization of insulin signaling processes and GLUT4 trafficking events Mechanisms of Insulin Action: Medical Intelligence Unit. 33-51. DOI: 10.1007/978-0-387-72204-7_2  0.368
2006 Zhang M, Liu J, Cheng A, DeYoung SM, Chen X, Dold LH, Saltiel AR. CAP interacts with cytoskeletal proteins and regulates adhesion-mediated ERK activation and motility Embo Journal. 25: 5284-5293. PMID 17082770 DOI: 10.1038/Sj.Emboj.7601406  0.581
2006 Chen XW, Inoue M, Hsu SC, Saltiel AR. RalA-exocyst-dependent recycling endosome trafficking is required for the completion of cytokinesis Journal of Biological Chemistry. 281: 38609-38616. PMID 17028198 DOI: 10.1074/Jbc.M512847200  0.571
2006 Kawase K, Nakamura T, Takaya A, Aoki K, Namikawa K, Kiyama H, Inagaki S, Takemoto H, Saltiel AR, Matsuda M. GTP Hydrolysis by the Rho Family GTPase TC10 Promotes Exocytic Vesicle Fusion Developmental Cell. 11: 411-421. PMID 16950130 DOI: 10.1016/J.Devcel.2006.07.008  0.371
2006 Su X, Lodhi IJ, Saltiel AR, Stahl PD. Insulin-stimulated interaction between insulin receptor substrate 1 and p85α and activation of protein kinase B/Akt require Rab5 Journal of Biological Chemistry. 281: 27982-27990. PMID 16880210 DOI: 10.1074/Jbc.M602873200  0.794
2006 Lumeng CN, Saltiel AR. Insulin htts on autophagy. Autophagy. 2: 250-3. PMID 16874093 DOI: 10.4161/Auto.2788  0.475
2006 Cheng A, Zhang M, Crosson SM, Bao ZQ, Saltiel AR. Regulation of the mouse protein targeting to glycogen (PTG) promoter by the FoxA2 forkhead protein and by 3′,5′-cyclic adenosine 5′-monophosphate in H4IIE hepatoma cells Endocrinology. 147: 3606-3612. PMID 16627590 DOI: 10.1210/En.2005-1513  0.36
2006 Lazar DF, Saltiel AR. Lipid phosphatases as drug discovery targets for type 2 diabetes Nature Reviews Drug Discovery. 5: 333-342. PMID 16582877 DOI: 10.1038/Nrd2007  0.405
2006 Inoue M, Chiang SH, Chang L, Chen XW, Saltiel AR. Compartmentalization of the exocyst complex in lipid rafts controls Glut4 vesicle tethering Molecular Biology of the Cell. 17: 2303-2311. PMID 16525015 DOI: 10.1091/Mbc.E06-01-0030  0.773
2006 Cheng A, Saltiel AR. More TORC for the gluconeogenic engine Bioessays. 28: 231-234. PMID 16479585 DOI: 10.1002/Bies.20375  0.504
2006 Chiang Sh, Chang L, Saltiel AR. TC10 and insulin-stimulated glucose transport Methods in Enzymology. 406: 701-714. PMID 16472699 DOI: 10.1016/S0076-6879(06)06055-1  0.756
2005 Saltiel AR. Holding the line on hepatic fat Cell Metabolism. 2: 1-2. PMID 16054091 DOI: 10.1016/J.Cmet.2005.06.010  0.332
2005 Liu J, DeYoung SM, Zhang M, Dold LH, Saltiel AR. The stomatin/prohibitin/flotillin/HflK/C domain of flotillin-1 contains distinct sequences that direct plasma membrane localization and protein interactions in 3T3-L1 adipocytes Journal of Biological Chemistry. 280: 16125-16134. PMID 15713660 DOI: 10.1074/Jbc.M500940200  0.355
2005 Decker SJ, Saltiel AR. Staying in SHIP shape Nature Medicine. 11: 123-124. PMID 15692594 DOI: 10.1038/Nm0205-123  0.311
2005 Saltiel AR. Signal transduction in insulin action. The Journal of Nutritional Biochemistry. 1: 180-8. PMID 15539202 DOI: 10.1016/0955-2863(90)90103-R  0.353
2004 Chang L, Chiang SH, Saltiel AR. Insulin signaling and the regulation of glucose transport Molecular Medicine. 10: 65-71. PMID 16307172 DOI: 10.2119/2005-00029.Saltiel  0.756
2004 Kanzaki M, Mora S, Hwang JB, Saltiel AR, Pessin JE. Atypical protein kinase C (PKCζ/λ) is a convergent downstream target of the insulin-stimulated phosphatidylinositol 3-kinase and TC10 signaling pathways Journal of Cell Biology. 164: 279-290. PMID 14734537 DOI: 10.1083/Jcb.200306152  0.547
2003 Saltiel AR. Putting the Brakes on Insulin Signaling New England Journal of Medicine. 349: 2560-2562. PMID 14695419 DOI: 10.1056/Nejmcibr031668  0.455
2003 Hu J, Liu J, Ghirlando R, Saltiel AR, Hubbard SR. Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor. Molecular Cell. 12: 1379-89. PMID 14690593 DOI: 10.1016/S1097-2765(03)00487-8  0.494
2003 Saltiel AR, Pessin JE. Insulin signaling in microdomains of the plasma membrane Traffic. 4: 711-716. PMID 14617354 DOI: 10.1034/J.1600-0854.2003.00119.X  0.566
2003 Saltiel AR. A TUG on glucose transport Nature Medicine. 9: 1352. PMID 14595425 DOI: 10.1038/Nm1103-1352  0.453
2003 Liu J, DeYoung SM, Hwang JB, O'Leary EE, Saltiel AR. The roles of Cbl-b and c-Cbl in insulin-stimulated glucose transport Journal of Biological Chemistry. 278: 36754-36762. PMID 12842890 DOI: 10.1074/Jbc.M300664200  0.573
2003 Chiang SH, Hwang J, Legendre M, Zhang M, Kimura A, Saltiel AR. TCGAP, a multidomain Rho GTpase-activating protein involved in insulin-stimulated glucose transport Embo Journal. 22: 2679-2691. PMID 12773384 DOI: 10.1093/Emboj/Cdg262  0.733
2003 Zhang M, Kimura A, Saltiel AR. Cloning and characterization of Cbl-associated protein splicing isoforms Molecular Medicine. 9: 18-25. PMID 12765336 DOI: 10.1007/Bf03402103  0.334
2003 Crosson SM, Khan A, Printen J, Pessin JE, Saltiel AR. PTG gene deletion causes impaired glycogen synthesis and developmental insulin resistance Journal of Clinical Investigation. 111: 1423-1432. PMID 12727934 DOI: 10.1172/Jci17975  0.5
2003 Inoue M, Chang L, Hwang J, Chiang SH, Saltiel AR. The exocyst complex is required for targeting of Glut4 to the plasma membrane by insulin Nature. 422: 629-633. PMID 12687004 DOI: 10.1038/Nature01533  0.701
2003 Watson RT, Furukawa M, Chiang SH, Boeglin D, Kanzaki M, Saltiel AR, Pessin JE. The exocytotic trafficking of TC10 occurs through both classical and nonclassical secretory transport pathways in 3T3L1 adipocytes. Molecular and Cellular Biology. 23: 961-74. PMID 12529401 DOI: 10.1128/Mcb.23.3.961-974.2003  0.581
2002 Chang L, Adams RD, Saltiel AR. The TC10-interacting protein CIP4/2 is required for insulin-stimulated Glut4 translocation in 3T3L1 adipocytes. Proceedings of the National Academy of Sciences of the United States of America. 99: 12835-40. PMID 12242347 DOI: 10.1073/Pnas.202495599  0.58
2002 Kanzaki M, Watson RT, Hou JC, Stamnes M, Saltiel AR, Pessin JE. Small GTP-binding protein TC10 differentially regulates two distinct populations of filamentous actin in 3T3L1 adipocytes. Molecular Biology of the Cell. 13: 2334-46. PMID 12134073 DOI: 10.1091/Mbc.01-10-0490  0.423
2002 Kimura A, Mora S, Shigematsu S, Pessin JE, Saltiel AR. The insulin receptor catalyzes the tyrosine phosphorylation of caveolin-1. Journal of Biological Chemistry. 277: 30153-30158. PMID 12036959 DOI: 10.1074/Jbc.M203375200  0.556
2002 Liu J, Kimura A, Baumann CA, Saltiel AR. APS facilitates c-Cbl tyrosine phosphorylation and GLUT4 translocation in response to insulin in 3T3-L1 adipocytes. Molecular and Cellular Biology. 22: 3599-609. PMID 11997497 DOI: 10.1128/Mcb.22.11.3599-3609.2002  0.569
2002 Saltiel AR, Pessin JE. Insulin signaling pathways in time and space Trends in Cell Biology. 12: 65-71. PMID 11849969 DOI: 10.1016/S0962-8924(01)02207-3  0.453
2002 Chiang SH, Hou JC, Hwang J, Pessin JE, Saltiel AR. Cloning and functional characterization of related TC10 isoforms, a subfamily of Rho proteins involved in insulin-stimulated glucose transport Journal of Biological Chemistry. 277: 13067-13073. PMID 11821390 DOI: 10.1074/Jbc.M109471200  0.743
2001 Saltiel AR, Kahn CR. Insulin signalling and the regulation of glucose and lipid metabolism Nature. 414: 799-806. PMID 11742412 DOI: 10.1038/414799A  0.521
2001 Watson RT, Shigematsu S, Chiang SH, Mora S, Kanzaki M, Macara IG, Saltiel AR, Pessin JE. Lipid raft microdomain compartmentalization of TC10 is required for insulin signaling and GLUT4 translocation. The Journal of Cell Biology. 154: 829-40. PMID 11502760 DOI: 10.1083/Jcb.200102078  0.726
2001 Kimura A, Baumann CA, Chiang SH, Saltiel AR. The sorbin homology domain: a motif for the targeting of proteins to lipid rafts. Proceedings of the National Academy of Sciences of the United States of America. 98: 9098-103. PMID 11481476 DOI: 10.1073/Pnas.151252898  0.682
2001 Saltiel AR. You are what you secrete Nature Medicine. 7: 887-888. PMID 11479613 DOI: 10.1038/90911  0.374
2001 Skinner JA, Saltiel AR. Cloning and identification of MYPT3: A prenylatable myosin targetting subunit of protein phosphatase 1 Biochemical Journal. 356: 257-267. PMID 11336659 DOI: 10.1042/Bj3560257  0.333
2001 Chiang SH, Baumann CA, Kanzaki M, Thurmond DC, Watson RT, Neudauer CL, Macara IG, Pessin JE, Saltiel AR. Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10. Nature. 410: 944-8. PMID 11309621 DOI: 10.1038/35073608  0.758
2001 Brady MJ, Saltiel AR. The role of protein phosphatase-1 in insulin action Recent Progress in Hormone Research. 56: 157-173. PMID 11237211 DOI: 10.1210/Rp.56.1.157  0.537
2001 Baumann CA, Saltiel AR. Spatial compartmentalization of signal transduction in insulin action. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 23: 215-22. PMID 11223878 DOI: 10.1002/1521-1878(200103)23:3<215::Aid-Bies1031>3.0.Co;2-S  0.537
2001 Baumann CA, Brady MJ, Saltiel AR. Activation of glycogen synthase by insulin in 3T3-L1 adipocytes involves c-Cbl-associating protein (CAP)-dependent and CAP-independent signaling pathways. The Journal of Biological Chemistry. 276: 6065-8. PMID 11222622 DOI: 10.1074/Jbc.C000856200  0.601
2000 Newgard CB, Brady MJ, O'Doherty RM, Saltiel AR. Organizing glucose disposal: emerging roles of the glycogen targeting subunits of protein phosphatase-1. Diabetes. 49: 1967-77. PMID 11117996 DOI: 10.2337/Diabetes.49.12.1967  0.487
2000 Olefsky JM, Saltiel AR. PPAR gamma and the treatment of insulin resistance. Trends in Endocrinology and Metabolism: Tem. 11: 362-8. PMID 11042466 DOI: 10.1016/S1043-2760(00)00306-4  0.487
2000 Baumann CA, Ribon V, Kanzaki M, Thurmond DC, Mora S, Shigematsu S, Bickel PE, Pessin JE, Saltiel AR. CAP defines a second signalling pathway required for insulin-stimulated glucose transport. Nature. 407: 202-7. PMID 11001060 DOI: 10.1038/35025089  0.608
2000 Fong NM, Jensen TC, Shah AS, Parekh NN, Saltiel AR, Brady MJ. Identification of binding sites on protein targeting to glycogen for enzymes of glycogen metabolism. The Journal of Biological Chemistry. 275: 35034-9. PMID 10938087 DOI: 10.1074/Jbc.M005541200  0.424
2000 Pessin JE, Saltiel AR. Signaling pathways in insulin action: molecular targets of insulin resistance. The Journal of Clinical Investigation. 106: 165-9. PMID 10903329 DOI: 10.1172/Jci10582  0.547
2000 Saltiel AR. Series introduction: the molecular and physiological basis of insulin resistance: emerging implications for metabolic and cardiovascular diseases. The Journal of Clinical Investigation. 106: 163-4. PMID 10903328 DOI: 10.1172/Jci10533  0.508
2000 Baumann CA, Chokshi N, Saltiel AR, Ribon V. Cloning and characterization of a functional peroxisome proliferator activator receptor-gamma-responsive element in the promoter of the CAP gene. The Journal of Biological Chemistry. 275: 9131-5. PMID 10734046 DOI: 10.1074/Jbc.275.13.9131  0.437
2000 Saltiel AR. Another hormone-sensitive triglyceride lipase in fat cells? Proceedings of the National Academy of Sciences of the United States of America. 97: 535-7. PMID 10639113 DOI: 10.1073/Pnas.97.2.535  0.344
1999 Brady MJ, Pessin JE, Saltiel AR. Spatial Compartmentalization in the Regulation of Glucose Metabolism by Insulin. Trends in Endocrinology and Metabolism: Tem. 10: 408-413. PMID 10542398 DOI: 10.1016/S1043-2760(99)00201-5  0.482
1999 Brady MJ, Saltiel AR. Closing in on the cause of insulin resistance and type 2 diabetes. The Journal of Clinical Investigation. 104: 675-6. PMID 10491401 DOI: 10.1172/Jci8216  0.612
1999 Brady MJ, Kartha PM, Aysola AA, Saltiel AR. The role of glucose metabolites in the activation and translocation of glycogen synthase by insulin in 3T3-L1 adipocytes. The Journal of Biological Chemistry. 274: 27497-504. PMID 10488084 DOI: 10.1074/Jbc.274.39.27497  0.562
1999 Syu LJ, Saltiel AR. Lipotransin: a novel docking protein for hormone-sensitive lipase. Molecular Cell. 4: 109-15. PMID 10445032 DOI: 10.1016/S1097-2765(00)80192-6  0.466
1999 Sebolt-Leopold JS, Dudley DT, Herrera R, Van Becelaere K, Wiland A, Gowan RC, Tecle H, Barrett SD, Bridges A, Przybranowski S, Leopold WR, Saltiel AR. Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo. Nature Medicine. 5: 810-6. PMID 10395327 DOI: 10.1038/10533  0.361
1999 Min J, Okada S, Kanzaki M, Elmendorf JS, Coker KJ, Ceresa BP, Syu LJ, Noda Y, Saltiel AR, Pessin JE. Synip: a novel insulin-regulated syntaxin 4-binding protein mediating GLUT4 translocation in adipocytes. Molecular Cell. 3: 751-60. PMID 10394363 DOI: 10.1016/S1097-2765(01)80007-1  0.552
1999 Kao AW, Noda Y, Johnson JH, Pessin JE, Saltiel AR. Aldolase mediates the association of F-actin with the insulin-responsive glucose transporter GLUT4. The Journal of Biological Chemistry. 274: 17742-7. PMID 10364216 DOI: 10.1074/Jbc.274.25.17742  0.555
1999 Hansen L, Fjordvang H, Rasmussen SK, Vestergaard H, Echwald SM, Hansen T, Alessi D, Shenolikar S, Saltiel AR, Barbetti F, Pedersen O. Mutational analysis of the coding regions of the genes encoding protein kinase B-alpha and -beta, phosphoinositide-dependent protein kinase-1, phosphatase targeting to glycogen, protein phosphatase inhibitor-1, and glycogenin: lessons from a search for genetic variability of the insulin-stimulated glycogen synthesis pathway of skeletal muscle in NIDDM patients. Diabetes. 48: 403-7. PMID 10334321 DOI: 10.2337/Diabetes.48.2.403  0.482
1999 Nakashima N, Rose DW, Xiao S, Egawa K, Martin SS, Haruta T, Saltiel AR, Olefsky JM. The functional role of CrkII in actin cytoskeleton organization and mitogenesis. The Journal of Biological Chemistry. 274: 3001-8. PMID 9915838 DOI: 10.1074/Jbc.274.5.3001  0.444
1998 Ribon V, Johnson JH, Camp HS, Saltiel AR. Thiazolidinediones and insulin resistance: peroxisome proliferatoractivated receptor gamma activation stimulates expression of the CAP gene. Proceedings of the National Academy of Sciences of the United States of America. 95: 14751-6. PMID 9843961 DOI: 10.1073/Pnas.95.25.14751  0.563
1998 Mastick CC, Brady MJ, Printen JA, Ribon V, Saltiel AR. Spatial determinants of specificity in insulin action. Molecular and Cellular Biochemistry. 182: 65-71. PMID 9609115 DOI: 10.1023/A:1006835430797  0.542
1998 Brady MJ, Bourbonais FJ, Saltiel AR. The activation of glycogen synthase by insulin switches from kinase inhibition to phosphatase activation during adipogenesis in 3T3-L1 cells. The Journal of Biological Chemistry. 273: 14063-6. PMID 9603900 DOI: 10.1074/Jbc.273.23.14063  0.558
1998 Su TZ, Wang M, Oxender DL, Saltiel AR. Troglitazone increases system A amino acid transport in 3T3-L1 cells. Endocrinology. 139: 832-7. PMID 9492010 DOI: 10.1210/Endo.139.3.5795  0.525
1998 Ribon V, Herrera R, Kay BK, Saltiel AR. A role for CAP, a novel, multifunctional Src homology 3 domain-containing protein in formation of actin stress fibers and focal adhesions. The Journal of Biological Chemistry. 273: 4073-80. PMID 9461600 DOI: 10.1074/Jbc.273.7.4073  0.36
1998 Desdouits-Magnen J, Desdouits F, Takeda S, Syu LJ, Saltiel AR, Buxbaum JD, Czernik AJ, Nairn AC, Greengard P. Regulation of secretion of Alzheimer amyloid precursor protein by the mitogen-activated protein kinase cascade. Journal of Neurochemistry. 70: 524-30. PMID 9453546 DOI: 10.1046/J.1471-4159.1998.70020524.X  0.416
1998 Su TZ, Wang M, Syu LJ, Saltiel AR, Oxender DL. Regulation of system A amino acid transport in 3T3-L1 adipocytes by insulin. The Journal of Biological Chemistry. 273: 3173-9. PMID 9452428 DOI: 10.1074/Jbc.273.6.3173  0.56
1998 Ribon V, Printen JA, Hoffman NG, Kay BK, Saltiel AR. A novel, multifuntional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytes. Molecular and Cellular Biology. 18: 872-9. PMID 9447983 DOI: 10.1128/Mcb.18.2.872  0.49
1997 Pircher TJ, Flores-Morales A, Mui AL, Saltiel AR, Norstedt G, Gustafsson JA, Haldosén LA. Mitogen-activated protein kinase kinase inhibition decreases growth hormone stimulated transcription mediated by STAT5. Molecular and Cellular Endocrinology. 133: 169-76. PMID 9406863 DOI: 10.1016/S0303-7207(97)00164-0  0.373
1997 Brady MJ, Nairn AC, Saltiel AR. The regulation of glycogen synthase by protein phosphatase 1 in 3T3-L1 adipocytes. Evidence for a potential role for DARPP-32 in insulin action. The Journal of Biological Chemistry. 272: 29698-703. PMID 9368038 DOI: 10.1074/Jbc.272.47.29698  0.526
1997 Syu LJ, Guan KL, Saltiel AR. Inducible expression of a mutant form of MEK1 in Swiss 3T3 cells. Journal of Cellular Biochemistry. 67: 367-77. PMID 9361191 DOI: 10.1002/(Sici)1097-4644(19971201)67:3<367::Aid-Jcb8>3.0.Co;2-U  0.379
1997 Kim B, Leventhal PS, Saltiel AR, Feldman EL. Insulin-like growth factor-I-mediated neurite outgrowth in vitro requires mitogen-activated protein kinase activation. The Journal of Biological Chemistry. 272: 21268-73. PMID 9261137 DOI: 10.1074/Jbc.272.34.21268  0.476
1997 Mastick CC, Saltiel AR. Insulin-stimulated tyrosine phosphorylation of caveolin is specific for the differentiated adipocyte phenotype in 3T3-L1 cells. The Journal of Biological Chemistry. 272: 20706-14. PMID 9252391 DOI: 10.1074/Jbc.272.33.20706  0.581
1997 Brady MJ, Printen JA, Mastick CC, Saltiel AR. Role of protein targeting to glycogen (PTG) in the regulation of protein phosphatase-1 activity. The Journal of Biological Chemistry. 272: 20198-204. PMID 9242697 DOI: 10.1074/Jbc.272.32.20198  0.48
1997 Ribon V, Saltiel AR. Insulin stimulates tyrosine phosphorylation of the proto-oncogene product of c-Cbl in 3T3-L1 adipocytes Biochemical Journal. 324: 839-845. PMID 9210408 DOI: 10.1042/Bj3240839  0.529
1997 Groskopf JC, Syu LJ, Saltiel AR, Linzer DIH. Proliferin induces endothelial cell chemotaxis through a G protein- coupled, mitogen-activated protein kinase-dependent pathway Endocrinology. 138: 2835-2840. PMID 9202225 DOI: 10.1210/Endo.138.7.5276  0.45
1997 Printen JA, Brady MJ, Saltiel AR. PTG, a protein phosphate 1-binding protein with a role in glycogen metabolism Science. 275: 1475-1478. PMID 9045612 DOI: 10.1126/Science.275.5305.1475  0.557
1997 O'Rourke CM, Davis JA, Saltiel AR, Cornicelli JA. Metabolic effects of troglitazone in the Goto-Kakizaki rat, a non-obese and normolipidemic rodent model of non-insulin-dependent diabetes mellitus Metabolism: Clinical and Experimental. 46: 192-198. PMID 9030828 DOI: 10.1016/S0026-0495(97)90301-2  0.456
1997 Wartmann M, Hofer P, Turowskit P, Saltiel AR, Hynes NE. Negative modulation of membrane localization of the Raf-1 protein kinase by hyperphosphorylation Journal of Biological Chemistry. 272: 3915-3923. PMID 9020094 DOI: 10.1074/Jbc.272.7.3915  0.436
1997 Párrizas M, Saltiel AR, LeRoith D. Insulin-like growth factor 1 inhibits apoptosis using the phosphatidylinositol 3'-kinase and mitogen-activated protein kinase pathways Journal of Biological Chemistry. 272: 154-161. PMID 8995241 DOI: 10.1074/Jbc.272.1.154  0.451
1996 Saltiel AR, Sawyer TK. Targeting signal transduction in the discovery of antiproliferative drugs Chemistry and Biology. 3: 887-893. PMID 8939707 DOI: 10.1016/S1074-5521(96)90177-5  0.324
1996 Saltiel AR, Olefsky JM. Thiazolidinediones in the treatment of insulin resistance and type II diabetes Diabetes. 45: 1661-1669. PMID 8922349 DOI: 10.2337/Diab.45.12.1661  0.496
1996 Martin SS, Rose DW, Saltiel AR, Klippel A, Williams LT, Olefsky JM. Phosphatidylinositol 3-kinase is necessary and sufficient for insulin- stimulated stress fiber breakdown Endocrinology. 137: 5045-5054. PMID 8895379 DOI: 10.1210/Endo.137.11.8895379  0.525
1996 Seely BL, Staubs PA, Reichart DR, Berhanu P, Milarski KL, Saltiel AR, Kusari J, Olefsky JM. Protein tyrosine phosphatase 1B interacts with the activated insulin receptor Diabetes. 45: 1379-1385. PMID 8826975 DOI: 10.2337/Diab.45.10.1379  0.537
1996 Saltiel AR. Structural and functional roles of glycosylphosphoinositides Sub-Cellular Biochemistry. 26: 165-185. PMID 8744265 DOI: 10.1007/978-1-4613-0343-5_6  0.378
1996 Morrison P, Saltiel AR, Rosner MR. Role of mitogen-activated protein kinase kinase in regulation of the epidermal growth factor receptor by protein kinase C Journal of Biological Chemistry. 271: 12891-12896. PMID 8662819 DOI: 10.1074/Jbc.271.22.12891  0.412
1996 Saltiel AR. Diverse signaling pathways in the cellular actions of insulin American Journal of Physiology - Endocrinology and Metabolism. 270: E375-E385. PMID 8638681 DOI: 10.1152/Ajpendo.1996.270.3.E375  0.583
1996 Ribon V, Saltiel AR. Nerve growth factor stimulates the tyrosine phosphorylation of endogenous Crk-II and augments its association with p130Cas in PC-12 cells Journal of Biological Chemistry. 271: 7375-7380. PMID 8631760 DOI: 10.1074/Jbc.271.13.7375  0.377
1996 Sasaoka T, Langlois WJ, Bai F, Rose DW, Leitner JW, Decker SJ, Saltiel AR, Gill GN, Kobayashi M, Draznin B, Olefsky JM. Involvement of ErbB2 in the signaling pathway leading to cell cycle progression from a truncated epidermal growth factor receptor lacking the C-terminal autophosphorylation sites Journal of Biological Chemistry. 271: 8338-8344. PMID 8626530 DOI: 10.1074/Jbc.271.14.8338  0.368
1996 Holt KH, Waters SB, Okada S, Yamauchi K, Decker SJ, Saltiel AR, Motto DG, Koretzky GA, Pessin JE. Epidermal growth factor receptor targeting prevents uncoupling of the Grb2-SOS complex Journal of Biological Chemistry. 271: 8300-8306. PMID 8626525 DOI: 10.1074/Jbc.271.14.8300  0.495
1996 Azpiazu I, Saltiel AR, DePaoli-Roach AA, Lawrence JC. Regulation of both glycogen synthase and PHAS-I by insulin in rat skeletal muscle involves mitogen-activated protein kinase-independent and rapamycin-sensitive pathways Journal of Biological Chemistry. 271: 5033-5039. PMID 8617780 DOI: 10.1074/Jbc.271.9.5033  0.566
1995 Wiese RJ, Mastick CC, Lazar DF, Saltiel AR. Activation of mitogen-activated protein kinase and phosphatidylinositol 3′-kinase is not sufficient for the hormonal stimulation of glucose uptake, lipogenesis, or glycogen synthesis in 3T3-L1 adipocytes Journal of Biological Chemistry. 270: 3442-3446. PMID 7852430 DOI: 10.1074/Jbc.270.7.3442  0.593
1995 Rani CSS, Abe A, Chang Y, Rosenzweig N, Saltiel AR, Radin NS, Shayman JA. Cell cycle arrest induced by an inhibitor of glucosylceramide synthase: Correlation with cyclin-dependent kinases Journal of Biological Chemistry. 270: 2859-2867. PMID 7852361 DOI: 10.1074/Jbc.270.6.2859  0.412
1995 Pang L, Sawada T, Decker SJ, Saltiel AR. Inhibition of MAP kinase kinase blocks the differentiation of PC-12 cells induced by nerve growth factor Journal of Biological Chemistry. 270: 13585-13588. PMID 7775407 DOI: 10.1074/Jbc.270.23.13585  0.374
1995 Maclean D, Sefler AM, Zhu G, Decker SJ, Saltiel AR, Singh J, McNamara D, Dobrusin EM, Sawyer TK. Differentiation of peptide molecular recognition by phospholipase Cγ-1 Src homology-2 domain and a mutant Tyr phosphatase PTP1b(C215S) Protein Science. 4: 13-20. PMID 7773170 DOI: 10.1002/Pro.5560040103  0.3
1995 Pang L, Zheng CF, Guan KL, Saltiel AR. Nerve growth factor stimulates a novel protein kinase in PC-12 cells that phosphorylates and activates mitogen-activated protein kinase kinase (MEK) Biochemical Journal. 307: 513-519. PMID 7733891 DOI: 10.1042/Bj3070513  0.411
1995 Sawada T, Milarski KL, Saltiel AR. Expression of a Catalytically Inert SYP Blocks Activation of Map Kinase Pathway Downstream of P21ras Biochemical and Biophysical Research Communications. 214: 737-743. PMID 7677789 DOI: 10.1006/Bbrc.1995.2347  0.554
1995 Waters SB, Holt KH, Ross SE, Syu LJ, Guan KL, Saltiel AR, Koretzky GA, Pessin JE. Desensitization of Ras activation by a feedback disassociation of the SOS-Grb2 complex Journal of Biological Chemistry. 270: 20883-20886. PMID 7673108 DOI: 10.1074/Jbc.270.36.20883  0.412
1995 Lazar DF, Wiese RJ, Brady MJ, Mastick CC, Waters SB, Yamauchi K, Pessin JE, Cuatrecasas P, Saltiel AR. Mitogen-activated protein kinase kinase inhibition does not block the stimulation of glucose utilization by insulin. The Journal of Biological Chemistry. 270: 20801-7. PMID 7657664 DOI: 10.1074/Jbc.270.35.20801  0.701
1995 Dudley DT, Pang L, Decker SJ, Bridges AJ, Saltiel AR. A synthetic inhibitor of the mitogen-activated protein kinase cascade Proceedings of the National Academy of Sciences of the United States of America. 92: 7686-7689. PMID 7644477 DOI: 10.1073/Pnas.92.17.7686  0.385
1995 Seely BL, Reichart DR, Staubs PA, Jhun BH, Hsu D, Maegawa H, Milarski KL, Saltiel AR, Olefsky JM. Localization of the insulin-like growth factor I receptor binding sites for the SH2 domain proteins p85, Syp, and GTPase activating protein Journal of Biological Chemistry. 270: 19151-19157. PMID 7642582 DOI: 10.1074/Jbc.270.32.19151  0.407
1995 Lin TA, Kong X, Saltiel AR, Blackshear PJ, Lawrence JC. Control of PHAS-I by insulin in 3T3-L1 adipocytes: Synthesis, degradation, and phosphorylation by a rapamycin-sensitive and mitogen-activated protein kinase-independent pathway Journal of Biological Chemistry. 270: 18531-18538. PMID 7629182 DOI: 10.1074/Jbc.270.31.18531  0.532
1995 Yamauchi K, Ribon V, Saltiel AR, Pessin JE. Identification of the major SHPTP2-binding protein that is tyrosine-phosphorylated in response to insulin Journal of Biological Chemistry. 270: 17716-17722. PMID 7629070 DOI: 10.1074/Jbc.270.30.17716  0.55
1995 Langlois WJ, Sasaoka T, Saltiel AR, Olefsky JM. Negative feedback regulation and desensitization of insulin-and epidermal growth factor-stimulated p21ras activation Journal of Biological Chemistry. 270: 25320-25323. PMID 7592690  0.407
1995 Jhun BH, Haruta T, Meinkoth JL, Leitner JW, Draznin B, Saltiel AR, Pang L, Sasaoka T, Olefsky JM. Signal transduction pathways leading to insulin-induced early gene induction Biochemistry. 34: 7996-8004. PMID 7540866 DOI: 10.1021/Bi00025A005  0.509
1995 Mastick CC, Brady MJ, Saltiel AR. Insulin stimulates the tyrosine phosphorylation of caveolin Journal of Cell Biology. 129: 1523-1531. PMID 7540611 DOI: 10.1083/Jcb.129.6.1523  0.578
1995 Milarski KL, Lazar DF, Wiese RJ, Saltiel AR. Detection of a 60 kDa tyrosine-phosphorylated protein in insulin-stimulated hepatoma cells that associates with the SH2 domain of phosphatidylinositol 3-kinase Biochemical Journal. 308: 579-583. PMID 7539611 DOI: 10.1042/Bj3080579  0.579
1995 Yamauchi K, Milarski KL, Saltiel AR, Pessin JE. Protein-tyrosine-phosphatase SHPTP2 is a required positive effector for insulin downstream signaling Proceedings of the National Academy of Sciences of the United States of America. 92: 664-668. PMID 7531337 DOI: 10.1073/Pnas.92.3.664  0.58
1995 Alessi DR, Cuenda A, Cohen P, Dudley DT, Saltiel AR. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo Journal of Biological Chemistry. 270: 27489-27494. PMID 7499206 DOI: 10.1074/Jbc.270.46.27489  0.416
1995 Whitcomb RW, Saltiel AR. Section review: Oncologic, endocrine & metabolic: Thiazolidinediones Expert Opinion On Investigational Drugs. 4: 1299-1309. DOI: 10.1517/13543784.4.12.1299  0.498
1995 Saltiel AR, Horilcoshi H. Thiazolidinediones are novel insulin-sensitizing agents Current Opinion in Endocrinology and Diabetes. 2: 341-347. DOI: 10.1097/00060793-199508000-00009  0.34
1994 Rose DW, Saltiel AR, Majumdar M, Decker SJ, Olefsky JM. Insulin receptor substrate 1 is required for insulin-mediated mitogenic signal transduction Proceedings of the National Academy of Sciences of the United States of America. 91: 797-801. PMID 8290602 DOI: 10.1073/Pnas.91.2.797  0.532
1994 Ohmichi M, Matuoka K, Takenawa T, Saltiel AR. Growth factors differentially stimulate the phosphorylation of Shc proteins and their association with Grb2 in PC-12 pheochromocytoma cells Journal of Biological Chemistry. 269: 1143-1148. PMID 8288573  0.415
1994 Zheng CF, Ohmichi M, Saltiel AR, Guan KL. Growth factor induced MEK activation is primarily mediated by an activator different from c-raf Biochemistry. 33: 5595-5599. PMID 8180183 DOI: 10.1021/Bi00184A031  0.404
1994 Pang L, Milarski KL, Ohmichi M, Takata Y, Olefsky JM, Saltiel AR. Mutation of the two carboxyl-terminal tyrosines in the insulin receptor results in enhanced activation of mitogen-activated protein kinase Journal of Biological Chemistry. 269: 10604-10608. PMID 8144649  0.471
1994 Ribon V, Leff T, Saltiel AR. c-Myc does not require Max for transcriptional activity in PC-12 cells Molecular and Cellular Neurosciences. 5: 277-282. PMID 8087425 DOI: 10.1006/Mcne.1994.1032  0.313
1994 Saltiel AR, Decker SJ. Cellular mechanisms of signal transduction for neurotrophins Bioessays. 16: 405-411. PMID 8080430 DOI: 10.1002/Bies.950160608  0.385
1994 Milarski KL, Saltiel AR. Expression of catalytically inactive Syp phosphatase in 3T3 cells blocks stimulation of mitogen-activated protein kinase by insulin Journal of Biological Chemistry. 269: 21239-21243. PMID 8063746  0.511
1994 Lingwood CA, Sakac D, Saltiel A. Developmentally regulated testicular galactolipid sulfotransferase inhibitor is a phosphoinositol glycerolipid and insulin-mimetic Molecular Reproduction and Development. 37: 462-466. PMID 8011331 DOI: 10.1002/Mrd.1080370414  0.562
1994 Pandey A, Lazar DF, Saltiel AR, Dixit VM. Activation of the Eck receptor protein tyrosine kinase stimulates phosphatidylinositol 3-kinase activity. The Journal of Biological Chemistry. 269: 30154-7. PMID 7982920  0.315
1994 Misek DE, Saltiel AR. An inositol phosphate glycan derived from a Trypanosoma brucei glycosyl phosphatidylinositol promotes protein dephosphorylation in rat epididymal adipocytes Endocrinology. 135: 1869-1876. PMID 7956908 DOI: 10.1210/Endo.135.5.7956908  0.562
1994 Jhun BH, Rose DW, Seely BL, Rameh L, Cantley L, Saltiel AR, Olefsky JM. Microinjection of the SH2 domain of the 85-kilodalton subunit of phosphatidylinositol 3-kinase inhibits insulin-induced DNA synthesis and c-fos expression Molecular and Cellular Biology. 14: 7466-7475. PMID 7935461 DOI: 10.1128/Mcb.14.11.7466  0.534
1994 Saltiel AR. The paradoxical regulation of protein phosphorylation in insulin action Faseb Journal. 8: 1034-1040. PMID 7926368 DOI: 10.1096/Fasebj.8.13.7926368  0.571
1994 Staubs PA, Reichart DR, Saltiel AR, Milarski KL, Maegawa H, Berhanu P, Olefsky JM, Seely BL. Localization of the insulin receptor binding sites for the SH2 domain proteins p85, Syp, and GAP Journal of Biological Chemistry. 269: 27186-27192. PMID 7525547  0.408
1994 Lazar DF, Knez JJ, Medof ME, Cuatrecasas P, Saltiel AR. Stimulation of glycogen synthesis by insulin in human erythroleukemia cells requires the synthesis of glycosyl-phosphatidylinositol. Proceedings of the National Academy of Sciences of the United States of America. 91: 9665-9. PMID 7524086 DOI: 10.1073/Pnas.91.21.9665  0.687
1994 Mastick CC, Kato H, Roberts CT, LeRoith D, Saltiel AR. Insulin and insulin-like growth factor-I receptors similarly stimulate deoxyribonucleic acid synthesis despite differences in cellular protein tyrosine phosphorylation Endocrinology. 135: 214-222. PMID 7516864 DOI: 10.1210/Endo.135.1.7516864  0.509
1994 Sasaoka T, Rose DW, Jhun BH, Saltiel AR, Draznin B, Olefsky JM. Evidence for a functional role of Shc proteins in mitogenic signaling induced by insulin, insulin-like growth factor-1, and epidermal growth factor Journal of Biological Chemistry. 269: 13689-13694. PMID 7513704  0.443
1994 Ohmichi M, Sawada T, Kanda Y, Koike K, Hirota K, Miyake A, Saltiel AR. Thyrotropin-releasing hormone stimulates MAP kinase activity in GH3 cells by divergent pathways: Evidence of a role for early tyrosine phosphorylation Journal of Biological Chemistry. 269: 3783-3788. PMID 7508919  0.33
1993 Pang L, Decker SJ, Saltiel AR. Bombesin and epidermal growth factor stimulate the mitogen-activated protein kinase through different pathways in Swiss 3T3 cells Biochemical Journal. 289: 283-287. PMID 8380987 DOI: 10.1042/Bj2890283  0.434
1993 Saltiel AR, Ohmichi M. Pleiotropic signaling from receptor tyrosine kinases. Current Opinion in Neurobiology. 3: 352-9. PMID 8369628 DOI: 10.1016/0959-4388(93)90128-L  0.311
1993 Ohmichi M, Zhu G, Saltiel AR. Nerve growth factor activates calcium-insensitive protein kinase C-epsilon in PC-12 rat pheochromocytoma cells. The Biochemical Journal. 767-72. PMID 8240290 DOI: 10.1042/Bj2950767  0.385
1993 Pang L, Lazar DF, Moller DE, Flier JS, Saltiel AR. The stimulation of pp42mapkinase by insulin does not correlate with its metabolic actions in cells overexpressing mutant insulin receptors. Biochemical and Biophysical Research Communications. 196: 301-10. PMID 8216304 DOI: 10.1006/Bbrc.1993.2249  0.546
1993 Ohmichi M, Pang L, Ribon V, Saltiel AR. Divergence of signaling pathways for insulin in PC-12 pheochromocytoma cells. Endocrinology. 133: 46-56. PMID 7686484 DOI: 10.1210/Endo.133.1.7686484  0.57
1993 Ohmichi M, Pang L, Ribon V, Gazit A, Levitzki A, Saltiel AR. The tyrosine kinase inhibitor tyrphostin blocks the cellular actions of nerve growth factor. Biochemistry. 32: 4650-8. PMID 7683492 DOI: 10.1021/Bi00068A024  0.396
1993 Pearl C, Saltiel AR. Regulation of Glycosyl-phosphoinositides in Mammalian Cells Neuroprotocols. 3: 119-124. DOI: 10.1006/Ncmn.1993.1045  0.317
1992 Saltiel AR, Decker SJ. Diversity in cellular signaling for nerve growth factor and insulin: variations on a common theme. Molecular and Cellular Endocrinology. 81: C197-202. PMID 1665824 DOI: 10.1016/0303-7207(91)90198-2  0.402
1992 Saltiel AR, Decker SJ. Diversity in cellular signaling for nerve growth factor and insulin: Variations on a common theme Journal of Investigative Dermatology. 98. PMID 1588123 DOI: 10.1111/1523-1747.Ep12462110  0.479
1992 Zhu G, Decker SJ, Saltiel AR. Direct analysis of the binding of Src-homology 2 domains of phospholipase C to the activated epidermal growth factor receptor Proceedings of the National Academy of Sciences of the United States of America. 89: 9559-9563. PMID 1384057 DOI: 10.1073/Pnas.89.20.9559  0.37
1992 Ohmichi M, Decker SJ, Saltiel AR. Activation of phosphatidylinositol-3 kinase by nerve growth factor involves indirect coupling of the trk proto-oncogene with src homology 2 domains Neuron. 9: 769-777. PMID 1382475 DOI: 10.1016/0896-6273(92)90039-G  0.407
1992 Ohmichi M, Decker SJ, Pang L, Saltiel AR. Inhibition of the cellular actions of nerve growth factor by staurosporine and K252A results from the attenuation of the activity of the trk tyrosine kinase Biochemistry. 31: 4034-4039. PMID 1314657 DOI: 10.1021/Bi00131A019  0.417
1992 Plourde R, D'Alarcao M, Saltiel AR. Synthesis and characterization of an insulin-mimetic disaccharide The Journal of Organic Chemistry. 57: 2606-2610. DOI: 10.1021/Jo00035A015  0.447
1991 Darnell JC, Osterman DG, Saltiel AR. Synthesis of phosphatidylinositol in rat liver microsomes is accompanied by the rapid formation of lysophosphatidylinositol. Biochimica Et Biophysica Acta. 1084: 269-78. PMID 1888775 DOI: 10.1016/0005-2760(91)90069-T  0.302
1991 Miyasaka T, Sternberg DW, Miyasaka J, Sherline P, Saltiel AR. Nerve growth factor stimulates protein tyrosine phosphorylation in PC-12 pheochromocytoma cells. Proceedings of the National Academy of Sciences of the United States of America. 88: 2653-7. PMID 1849270 DOI: 10.1073/Pnas.88.7.2653  0.404
1991 Saltiel AR. The role of glycosyl-phosphoinositides in hormone action. Journal of Bioenergetics and Biomembranes. 23: 29-41. PMID 1849135 DOI: 10.1007/Bf00768837  0.556
1991 Saltiel AR, Ravetch J, Aderem AA. Functional consequences of lipid-mediated protein-membrane interactions. Biochemical Pharmacology. 42: 1-11. PMID 1829888 DOI: 10.1016/0006-2952(91)90673-S  0.315
1991 Ohmichi M, Decker SJ, Pang L, Saltiel AR. Nerve growth factor binds to the 140 kd trk proto-oncogene product and stimulates its association with the src homology domain of phospholipase C γ1 Biochemical and Biophysical Research Communications. 179: 217-223. PMID 1715690 DOI: 10.1016/0006-291X(91)91357-I  0.36
1991 Shapiro E, Brown SD, Saltiel AR, Schwartz JH. Short-term action of insulin on Aplysia neurons: generation of a possible novel modulator of ion channels. Journal of Neurobiology. 22: 55-62. PMID 1707088 DOI: 10.1002/Neu.480220106  0.473
1991 Ohmichi M, Decker SJ, Saltiel AR. Nerve growth factor induces the association of a 130-Kd phosphoprotein with its receptor in PC-12 pheochromocytoma cells Cell Regulation. 2: 691-697. PMID 1660308 DOI: 10.1091/Mbc.2.9.691  0.364
1991 Hess SL, Suchin CR, Saltiel AR. The specific protein phosphatase inhibitor okadaic acid differentially modulates insulin action Journal of Cellular Biochemistry. 45: 374-380. PMID 1646209 DOI: 10.1002/Jcb.240450411  0.522
1990 Pfeffer LM, Strulovici B, Saltiel AR. Interferon-alpha selectively activates the beta isoform of protein kinase C through phosphatidylcholine hydrolysis. Proceedings of the National Academy of Sciences of the United States of America. 87: 6537-41. PMID 2168551 DOI: 10.1073/Pnas.87.17.6537  0.374
1990 Miyasaka T, Miyasaka J, Saltiel AR. Okadaic acid stimulates the activity of microtubule associated protein kinase in PC-12 pheochromocytoma cells. Biochemical and Biophysical Research Communications. 168: 1237-43. PMID 2161219 DOI: 10.1016/0006-291X(90)91161-K  0.406
1990 Listani MP, Rodriguez-Boulan E, Saltiel AR. Emerging functional roles for the glycosyl-phosphatidylinositol membrane protein anchor Journal of Membrane Biology. 117: 1-10. PMID 2144878 DOI: 10.1007/Bf01871561  0.338
1990 Saltiel AR. Second messengers of insulin action. Diabetes Care. 13: 244-56. PMID 2137771 DOI: 10.2337/Diacare.13.3.244  0.559
1990 Schwartz JH, Shapiro E, Brown SD, Saltiel AR. Short-term electrophysiological actions of insulin on Aplysia neurons: identification of a possible novel modulatory second-messenger mechanism. Cold Spring Harbor Symposia On Quantitative Biology. 55: 95-100. PMID 1983449 DOI: 10.1101/Sqb.1990.055.01.012  0.386
1989 Saltiel AR, Osterman DG, Darnell JC, Chan BL, Sorbara-Cazan LR. The role of glycosylphosphoinositides in signal transduction. Recent Progress in Hormone Research. 45: 353-79; discussion 3. PMID 2682844 DOI: 10.1016/B978-0-12-571145-6.50011-X  0.53
1989 Chan BL, Chao MV, Saltiel AR. Nerve growth factor stimulates the hydrolysis of glycosylphosphatidylinositol in PC-12 cells: a mechanism of protein kinase C regulation. Proceedings of the National Academy of Sciences of the United States of America. 86: 1756-60. PMID 2538812 DOI: 10.1073/Pnas.86.6.1756  0.396
1989 Lisanti MP, Darnell JC, Chan BL, Rodriguez-Boulan E, Saltiel AR. The distribution of glycosyl-phosphatidylinositol anchored proteins is differentially regulated by serum and insulin Biochemical and Biophysical Research Communications. 164: 824-832. PMID 2530980 DOI: 10.1016/0006-291X(89)91533-7  0.449
1988 Saltiel AR, Sorbara-Cazan LR. Inositol glycan mimics the action of insulin on glucose utilization in rat adipocytes. Biochemical and Biophysical Research Communications. 149: 1084-92. PMID 3322285 DOI: 10.1016/0006-291X(87)90519-5  0.529
1988 Low MG, Saltiel AR. Structural and functional roles of glycosyl-phosphatidylinositol in membranes. Science (New York, N.Y.). 239: 268-75. PMID 3276003 DOI: 10.1126/Science.3276003  0.394
1988 Lisanti MP, Sargiacomo M, Graeve L, Saltiel AR, Rodriguez-Boulan E. Polarized apical distribution of glycosyl-phosphatidylinositol-anchored proteins in a renal epithelial cell line Proceedings of the National Academy of Sciences of the United States of America. 85: 9557-9561. PMID 2974157 DOI: 10.1073/Pnas.85.24.9557  0.31
1988 Saltiel AR, Osterman DG, Darnell JC, Sorbara-Cazan LR, Chan BL, Low MG, Cuatrecasas P. The function of glycosyl phosphoinositides in hormone action. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 320: 345-58. PMID 2906143 DOI: 10.1098/Rstb.1988.0081  0.643
1988 Saltiel AR, Osterman DG, Darnell JC. Role of glycosyl phosphoinositides in insulin action. Cold Spring Harbor Symposia On Quantitative Biology. 53: 955-63. PMID 2855505 DOI: 10.1101/Sqb.1988.053.01.110  0.503
1988 Chan BL, Lisanti MP, Rodriguez-Boulan E, Saltiel AR. Insulin-stimulated release of lipoprotein lipase by metabolism of its phosphatidylinositol anchor Science. 241: 1670-1672. PMID 2843987 DOI: 10.1126/Science.2843987  0.535
1988 Saltiel AR, Cuatrecasas P. In search of a second messenger for insulin. The American Journal of Physiology. 255: C1-11. PMID 2839033 DOI: 10.1152/Ajpcell.1988.255.1.C1  0.69
1987 Saltiel AR, Fox JA, Sherline P, Sahyoun N, Cuatrecasas P. Purification of phosphatidylinositol kinase from bovine brain myelin. The Biochemical Journal. 241: 759-63. PMID 3036072 DOI: 10.1042/Bj2410759  0.533
1987 Fox JA, Soliz NM, Saltiel AR. Purification of a phosphatidylinositol-glycan-specific phospholipase C from liver plasma membranes: a possible target of insulin action. Proceedings of the National Academy of Sciences of the United States of America. 84: 2663-7. PMID 3033658 DOI: 10.1073/Pnas.84.9.2663  0.433
1987 Saltiel AR. Insulin generates an enzyme modulator from hepatic plasma membranes: regulation of adenosine 3',5'-monophosphate phosphodiesterase, pyruvate dehydrogenase, and adenylate cyclase. Endocrinology. 120: 967-72. PMID 3026792 DOI: 10.1210/Endo-120-3-967  0.448
1986 Saltiel AR, Fox JA, Sherline P, Cuatrecasas P. Insulin-stimulated hydrolysis of a novel glycolipid generates modulators of cAMP phosphodiesterase. Science (New York, N.Y.). 233: 967-72. PMID 3016898 DOI: 10.1126/Science.3016898  0.64
1986 Saltiel AR, Cuatrecasas P. Insulin stimulates the generation from hepatic plasma membranes of modulators derived from an inositol glycolipid. Proceedings of the National Academy of Sciences of the United States of America. 83: 5793-7. PMID 3016721 DOI: 10.1073/Pnas.83.16.5793  0.641
1986 Saltiel AR, Steigerwalt RW. Purification of putative insulin-sensitive cAMP phosphodiesterase or its catalytic domain from rat adipocytes. Diabetes. 35: 698-704. PMID 3011573 DOI: 10.2337/Diab.35.6.698  0.471
1983 Jacobs S, Sahyoun NE, Saltiel AR, Cuatrecasas P. Phorbol esters stimulate the phosphorylation of receptors for insulin and somatomedin C. Proceedings of the National Academy of Sciences of the United States of America. 80: 6211-3. PMID 6312447 DOI: 10.1073/Pnas.80.20.6211  0.662
1983 Saltiel AR, Doble A, Jacobs S, Cuatrecasas P. Putative mediators of insulin action regulate hepatic acetyl CoA carboxylase activity. Biochemical and Biophysical Research Communications. 110: 789-95. PMID 6132601 DOI: 10.1016/0006-291X(83)91031-8  0.663
1982 Saltiel AR, Siegel MI, Jacobs S, Cuatrecasas P. Putative mediators of insulin action: regulation of pyruvate dehydrogenase and adenylate cyclase activities. Proceedings of the National Academy of Sciences of the United States of America. 79: 3513-7. PMID 7048309 DOI: 10.1073/Pnas.79.11.3513  0.672
1981 Saltiel A, Jacobs S, Siegel M, Cuatrecasas P. Insulin stimulates the release from liver plasma membranes of a chemical modulator of pyruvate dehydrogenase. Biochemical and Biophysical Research Communications. 102: 1041-7. PMID 7030345 DOI: 10.1016/0006-291X(81)91643-0  0.645
1981 Powell-Jones CH, Saltiel AR, Thomas CG, Nayfeh SN. Dissociation kinetics of the thyrotropin-receptor complex. Characterization of a slowly dissociable component. Molecular and Cellular Endocrinology. 24: 219-31. PMID 6271612 DOI: 10.1016/0303-7207(81)90061-7  0.346
1981 Saltiel AR, Powell-Jones CH, Thomas CG, Nayfeh SN. Regulation of thyroid adenylate cyclase: guanyl nucleotide modulation of thyrotropin receptor-adenylate cyclase function. Endocrinology. 109: 1578-89. PMID 6271536 DOI: 10.1210/Endo-109-5-1578  0.345
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