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Bruce A. Freeman - Publications

Affiliations: 
1982-1985 Medicine Duke University, Durham, NC 
 1985-2005 Anesthesiology, Biochemistry and Molecular Genetics University of Alabama, Birmingham, Birmingham, AL, United States 
 2006- Pharmacology and Chemical Biology University of Pittsburgh, Pittsburgh, PA, United States 
Area:
eukaryotic cell production, reactions and signal transduction properties of oxidizing and free radical inflammatory mediators
Website:
http://pharmacology.medicine.pitt.edu/Faculty/BruceFreeman
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272 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Koudelka A, Buchan GJ, Cechova V, O'Brien JP, Liu H, Woodcock SR, Mullett SJ, Zhang C, Freeman BA, Gelhaus SL. Lipoxin A yields an electrophilic 15-oxo metabolite that mediates FPR2 receptor-independent anti-inflammatory signaling. Biorxiv : the Preprint Server For Biology. PMID 38370667 DOI: 10.1101/2024.02.06.579101  0.358
2021 Fazzari M, Woodcock SR, Rowart P, Ricart K, Lancaster JR, Patel R, Vitturi DA, Freeman BA, Schopfer FJ. Endogenous generation of nitro-fatty acid hybrids having dual nitrate ester (RONO) and nitroalkene (RNO) substituents. Redox Biology. 41: 101913. PMID 33819836 DOI: 10.1016/j.redox.2021.101913  0.414
2020 Grippo V, Mojovic M, Pavicevic A, Kabelac M, Hubatka F, Turanek J, Zatloukalova M, Freeman BA, Vacek J. Electrophilic characteristics and aqueous behavior of fatty acid nitroalkenes. Redox Biology. 38: 101756. PMID 33181478 DOI: 10.1016/j.redox.2020.101756  0.398
2020 Mollenhauer M, Mehrkens D, Klinke A, Lange M, Remane L, Friedrichs K, Braumann S, Geißen S, Simsekyilmaz S, Nettersheim FS, Lee S, Peinkofer G, Geisler AC, Geis B, Schwoerer AP, ... ... Freeman BA, et al. Nitro-fatty acids suppress ischemic ventricular arrhythmias by preserving calcium homeostasis. Scientific Reports. 10: 15319. PMID 32948795 DOI: 10.1038/S41598-020-71870-6  0.387
2020 Wilkinson ML, Abramova E, Guo C, Gow JG, Murray A, Koudelka A, Cechova V, Freeman BA, Gow AJ. Fatty acid nitroalkenes inhibit the inflammatory response to bleomycin-mediated lung injury. Toxicology and Applied Pharmacology. 115236. PMID 32931793 DOI: 10.1016/J.Taap.2020.115236  0.315
2020 Zhao Y, Chang Z, Zhao G, Lu H, Xiong W, Liang W, Wang H, Villacorta L, Garcia-Barrio MT, Zhu T, Guo Y, Fan Y, Chang L, Schopfer FJ, Freeman BA, et al. Suppression of Vascular Macrophage Activation by Nitro-Oleic Acid and its Implication for Abdominal Aortic Aneurysm Therapy. Cardiovascular Drugs and Therapy. PMID 32671602 DOI: 10.1007/S10557-020-07031-8  0.304
2020 Vazquez MM, Gutierrez MV, Salvatore SR, Puiatti M, Dato VA, Chiabrando GA, Freeman BA, Schopfer FJ, Bonacci G. Nitro-oleic acid, a ligand of CD36, reduces cholesterol accumulation by modulating oxidized-LDL uptake and cholesterol efflux in RAW264.7 macrophages. Redox Biology. 36: 101591. PMID 32531545 DOI: 10.1016/J.Redox.2020.101591  0.381
2020 Bervejillo ML, Bonanata J, Franchini GR, Richeri A, Marqués JM, Freeman BA, Schopfer FJ, Coitiño EL, Córsico B, Rubbo H, Ferreira AM. A FABP4-PPARγ signaling axis regulates human monocyte responses to electrophilic fatty acid nitroalkenes Redox Biology. 29: 101376. PMID 31926616 DOI: 10.1016/J.Redox.2019.101376  0.486
2020 Fazzari M, Woodcock SR, Rowart P, Lancaster JJ, Vitturi DA, Freeman BA, Schopfer FJ. Corrigendum to “Endogenous formation of novel nitro-nitrate species as intermediates of fatty acid nitration” [Free Radic. Biol. Med. 145(1) (2019) S22] Free Radical Biology and Medicine. DOI: 10.1016/J.Freeradbiomed.2020.01.180  0.417
2019 Zatloukalova M, Mojovic M, Pavicevic A, Kabelac M, Freeman BA, Pekarova M, Vacek J. Redox properties and human serum albumin binding of nitro-oleic acid. Redox Biology. 24: 101213. PMID 31170679 DOI: 10.1016/J.Redox.2019.101213  0.435
2019 Lu H, Sun J, Liang W, Zhang J, Rom O, Garcia-Barrio MT, Li S, Villacorta L, Schopfer FJ, Freeman BA, Chen YE, Fan Y. Novel gene regulatory networks identified in response to nitro-conjugated linoleic acid in human endothelial cells. Physiological Genomics. PMID 31074702 DOI: 10.1152/Physiolgenomics.00127.2018  0.499
2019 Khoo NKH, Fazzari M, Chartoumpekis DV, Li L, Guimaraes DA, Arteel GE, Shiva S, Freeman BA. Electrophilic nitro-oleic acid reverses obesity-induced hepatic steatosis. Redox Biology. 22: 101132. PMID 30769284 DOI: 10.1016/J.Redox.2019.101132  0.333
2018 Woodcock SR, Wendell SG, Schopfer FJ, Freeman BA. Synthesis of an Electrophilic Keto-Tetraene 15-oxo-Lipoxin A Methyl Ester a MIDA Boronate. Tetrahedron Letters. 59: 3524-3527. PMID 31379396 DOI: 10.1016/J.Tetlet.2018.08.014  0.317
2018 Jobbagy S, Vitturi DA, Salvatore SR, Turell L, Pires MF, Kansanen E, Batthyany C, Lancaster JR, Freeman BA, Schopfer FJ. Electrophiles modulate glutathione reductase activity via alkylation and upregulation of glutathione biosynthesis. Redox Biology. 21: 101050. PMID 30654300 DOI: 10.1016/J.Redox.2018.11.008  0.465
2018 Fazzari M, Vitturi DA, Woodcock SR, Salvatore SR, Freeman BA, Schopfer FJ. Electrophilic fatty acid nitroalkenes are systemically transported and distributed upon esterification to complex lipids. Journal of Lipid Research. PMID 30545956 DOI: 10.1194/Jlr.M088815  0.434
2018 Asan A, Skoko JJ, Woodcock CC, Wingert BM, Woodcock SR, Normolle D, Huang Y, Stark JM, Camacho CJ, Freeman BA, Neumann CA. Electrophilic fatty acids impair RAD51 function and potentiate the effects of DNA- damaging agents on growth of triple-negative breast cells. The Journal of Biological Chemistry. PMID 30478172 DOI: 10.1074/Jbc.Ac118.005899  0.369
2018 Rodriguez-Duarte J, Dapueto R, Galliussi G, Turell L, Kamaid A, Khoo NKH, Schopfer FJ, Freeman BA, Escande C, Batthyány C, Ferrer-Sueta G, López GV. Electrophilic nitroalkene-tocopherol derivatives: synthesis, physicochemical characterization and evaluation of anti-inflammatory signaling responses. Scientific Reports. 8: 12784. PMID 30143727 DOI: 10.1038/S41598-018-31218-7  0.372
2018 Schopfer FJ, Vitturi DA, Jorkasky DK, Freeman BA. Nitro-fatty acids: New drug candidates for chronic inflammatory and fibrotic diseases. Nitric Oxide : Biology and Chemistry. PMID 29944935 DOI: 10.1016/J.Niox.2018.06.006  0.357
2018 Freeman BA, O'Donnell VB, Schopfer FJ. The discovery of nitro-fatty acids as products of metabolic and inflammatory reactions and mediators of adaptive cell signaling. Nitric Oxide : Biology and Chemistry. 77: 106-111. PMID 29742447 DOI: 10.1016/J.Niox.2018.05.002  0.496
2018 Li S, Chang Z, Zhu T, Li Y, Freeman BA, Chen YE, Zhang J. Transcriptomic sequencing reveals diverse adaptive gene expression responses of human vascular smooth muscle cells to nitro-conjugated linoleic acid. Physiological Genomics. PMID 29473818 DOI: 10.1152/Physiolgenomics.00090.2017  0.417
2018 Villacorta L, Minarrieta L, Salvatore SR, Khoo NK, Rom O, Gao Z, Berman RC, Jobbagy S, Li L, Woodcock SR, Chen YE, Freeman BA, Ferreira AM, Schopfer FJ, Vitturi DA. In situ generation, metabolism and immunomodulatory signaling actions of nitro-conjugated linoleic acid in a murine model of inflammation. Redox Biology. 15: 522-531. PMID 29413964 DOI: 10.1016/J.Redox.2018.01.005  0.44
2018 Khoo NKH, Li L, Salvatore SR, Schopfer FJ, Freeman BA. Electrophilic fatty acid nitroalkenes regulate Nrf2 and NF-κB signaling:A medicinal chemistry investigation of structure-function relationships. Scientific Reports. 8: 2295. PMID 29396403 DOI: 10.1038/S41598-018-20460-8  0.419
2018 Woodcock C, Woodcock S, Salvatore S, Davidson N, Huang Y, Freeman B. Electrophilic Nitro‐oleic Acid Inhibits Triple Negative Breast Cancer Cell Migration via Suppression of NF‐kB activity The Faseb Journal. 31. DOI: 10.1096/Fasebj.31.1_Supplement.934.1  0.306
2018 Skoko J, Asan A, Woodcock C, Cao J, Gaboriau D, Paulsen C, Attar M, Wingert B, Woodcock S, Schulte J, Ma H, Camacho C, Liu Y, Morrison C, Carroll K, ... Freeman B, et al. Loss of PRDX1 increases RAD51 Cys319 oxidation and decreases homologous recombination Free Radical Biology and Medicine. 128: S73-S74. DOI: 10.1016/J.Freeradbiomed.2018.10.159  0.368
2018 Kamarytova K, Kudova J, Cechova V, Koreny M, Hoferova Z, Freeman B, Pekarova M. Nitro-oleic acid regulates differentiation of embryonic stem cells Free Radical Biology and Medicine. 128: S53. DOI: 10.1016/J.Freeradbiomed.2018.10.095  0.364
2017 D'Amore A, Fazzari M, Jiang H, Luketich SK, Luketich ME, Hoff RF, Jacobs DL, Gu X, Badylak SF, Freeman BA, Wagner WR. Nitro-oleic acid (NO2OA) release enhances regional angiogenesis in a rat abdominal wall defect model. Tissue Engineering. Part A. PMID 29187125 DOI: 10.1089/Ten.Tea.2017.0349  0.323
2017 Woodcock CC, Huang Y, Woodcock SR, Salvatore SR, Singh B, Golin-Bisello F, Davidson NE, Neumann C, Freeman BA, Wendell SG. Nitro-fatty acid inhibition of triple negative breast cancer cell viability, migration, invasion and tumor growth. The Journal of Biological Chemistry. PMID 29158255 DOI: 10.1074/Jbc.M117.814368  0.356
2017 Mathers AR, Carey CD, Killeen ME, Salvatore SR, Ferris LK, Freeman BA, Schopfer FJ, Falo LD. Topical electrophilic nitro-fatty acids potentiate cutaneous inflammation. Free Radical Biology & Medicine. PMID 29132974 DOI: 10.1016/J.Freeradbiomed.2017.11.009  0.402
2017 Hughan KS, Wendell SG, Delmastro-Greenwood M, Helbling N, Corey C, Bellavia L, Potti G, Grimes G, Goodpaster B, Kim-Shapiro DB, Shiva S, Freeman BA, Gladwin MT. Conjugated Linoleic Acid Modulates Clinical Responses to Oral Nitrite and Nitrate. Hypertension (Dallas, Tex. : 1979). PMID 28739973 DOI: 10.1161/Hypertensionaha.117.09016  0.496
2017 Verescakova H, Ambrozova G, Kubala L, Perecko T, Koudelka A, Vasicek O, Rudolph TK, Klinke A, Woodcock SR, Freeman BA, Pekarova M. Nitro-oleic acid regulates growth factor-induced differentiation of bone marrow-derived macrophages. Free Radical Biology & Medicine. PMID 28063941 DOI: 10.1016/J.Freeradbiomed.2017.01.003  0.384
2017 Fazzari M, Chartoumpekis D, Li L, Guimaraes DA, Shiva S, Freeman BA, Khoo N. Nitro-oleic Acid Protects Mice from Diet-Induced Hepatic Steatosis and Insulin Resistance without the Adverse Side Effects of Thiazolidinediones Free Radical Biology and Medicine. 112: 152. DOI: 10.1016/J.Freeradbiomed.2017.10.232  0.351
2017 Kudova J, Koudelka A, Cechova V, Koreny M, Kubala L, Klinke A, Rudolph V, Freeman BA, Pekarova M. Nitro-oleic Acid Regulates Fibroblast Functions in Different Profibrotic Models Free Radical Biology and Medicine. 112: 146. DOI: 10.1016/J.Freeradbiomed.2017.10.222  0.38
2017 Koudelka A, Ambrozova G, Kudova J, Kubala L, Cechova V, Koreny M, Klinke A, Rudolph V, Freeman BA, Pekarova M. Protective Role of Nitro-oleic Acid in Development of Vascular Dysfunction Free Radical Biology and Medicine. 112: 145. DOI: 10.1016/J.Freeradbiomed.2017.10.221  0.436
2017 Vitturi DA, Straub A, Maynard C, Freeman BA, Kim F, Dezfulian C. Role for Nitro-Conjugated Linoleic Acid and cGMP in Nitrite-Mediated Neuroprotection in Out-of-Hospital Cardiac Arrest Free Radical Biology and Medicine. 112: 136. DOI: 10.1016/J.Freeradbiomed.2017.10.208  0.366
2017 Skoko JJ, Asan A, Woodcock CC, Cao J, Gaboriau D, Paulsen CE, Attar M, Wingert BM, Woodcock SR, Schulte J, Ma H, Camacho CJ, Liu Y, Morrison CG, Carroll K, ... Freeman BA, et al. Redox Regulation of RAD51 and Homologous Recombination by Peroxiredoxin 1 and Electrophilic Nitro-fatty Acids Free Radical Biology and Medicine. 112: 100-101. DOI: 10.1016/J.Freeradbiomed.2017.10.151  0.366
2017 Woodcock CS, Woodcock SR, Salvatore SR, Singh B, Golin-Bisello F, Davidson NE, Huang Y, Wendell SG, Freeman BA. Selective Inhibition of Triple Negative Breast Cancer Cell Mobility and Viability by Nitro-Oleic Acid Free Radical Biology and Medicine. 112: 99. DOI: 10.1016/J.Freeradbiomed.2017.10.148  0.368
2017 Wendell SL, Buchan G, Singh B, Deshpande R, Holguin F, Wenzel S, Freeman BA. Targeting obesity-driven asthma with nitrate, nitrite and conjugated linoleic acid therapy Free Radical Biology and Medicine. 112: 45. DOI: 10.1016/J.Freeradbiomed.2017.10.060  0.301
2017 Rubbo H, Trostchansky A, Mastrogiovanni M, Martinez-Palma L, Cassina P, Freeman BA. Lipidomics and therapeutic potential of nitro-oleic acid acid in a model of familial ALS Free Radical Biology and Medicine. 112: 44. DOI: 10.1016/J.Freeradbiomed.2017.10.058  0.383
2017 Schopfer F, Freeman B, Jorkasky D. Clinical Evaluation of the Safety and Therapeutic Potential of the Electrophilic Fatty Acid Nitroalkene 10-nitro-octadec-9-enoic acid (10-NO 2 -OA) Free Radical Biology and Medicine. 112: 43. DOI: 10.1016/J.Freeradbiomed.2017.10.056  0.474
2017 Buchan GJ, Manni ML, Lakdawala SS, Freeman BA, Wendell SG. Using electrophilic fatty acid derivatives to tame host-induced lung injury during influenza infection Free Radical Biology and Medicine. 112: 41. DOI: 10.1016/J.Freeradbiomed.2017.10.052  0.351
2016 Koch CD, Gladwin MT, Freeman BA, Lundberg JO, Weitzberg E, Morris A. Enterosalivary nitrate metabolism and the microbiome: intersection of microbial metabolism, nitric oxide and diet in cardiac and pulmonary vascular health. Free Radical Biology & Medicine. PMID 27989792 DOI: 10.1016/J.Freeradbiomed.2016.12.015  0.382
2016 Fazzari M, Khoo NK, Woodcock SR, Jorkasky DK, Li L, Schopfer FJ, Freeman BA. Nitro-fatty acid pharmacokinetics in the adipose tissue compartment. Journal of Lipid Research. PMID 27913584 DOI: 10.1016/J.Freeradbiomed.2016.10.172  0.466
2016 Koudelka A, Ambrozova G, Klinke A, Fidlerova T, Martiskova H, Kuchta R, Rudolph TK, Kadlec J, Kuchtova Z, Woodcock SR, Freeman BA, Kubala L, Pekarova M. Nitro-Oleic Acid Prevents Hypoxia- and Asymmetric Dimethylarginine-Induced Pulmonary Endothelial Dysfunction. Cardiovascular Drugs and Therapy. PMID 27858190 DOI: 10.1007/S10557-016-6700-3  0.34
2016 Mathers AR, Carey CD, Killeen ME, Diaz-Perez J, Salvatore SR, Schopfer FJ, Freeman BA, Falo LD. Electrophilic nitro-fatty acids suppress allergic contact dermatitis in mice. Allergy. PMID 27718238 DOI: 10.1111/All.13067  0.485
2016 Winnica D, Que LG, Baffi C, Grasemann H, Fiedler K, Yang Z, Etling E, Wasil K, Wenzel SE, Freeman B, Holguin F. L-citrulline prevents Asymmetric Dimethylarginine-Mediated reductions in Nitric Oxide and Nitrosative Stress In Primary Human Airway Epithelial Cells. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. PMID 27562295 DOI: 10.1111/Cea.12802  0.392
2016 Ambrozova G, Fidlerova T, Martiskova H, Koudelka A, Rudolph TK, Woodcock SR, Freeman BA, Kubala L, Pekarova M. Nitro-Oleic Acid Inhibits Vascular Endothelial Inflammatory Responses and The Endothelial-Mesenchymal Transition. Biochimica Et Biophysica Acta. PMID 27431604 DOI: 10.1016/J.Bbagen.2016.07.010  0.417
2016 Zhou C, Ramaswamy SS, Johnson DE, Vitturi DA, Schopfer FJ, Freeman BA, Hudmon A, Levitan ES. Novel Roles for Peroxynitrite in Angiotensin II and CaMKII Signaling. Scientific Reports. 6: 23416. PMID 27079272 DOI: 10.1038/Srep23416  0.357
2016 Diaz-Amarilla P, Miquel E, Trostchansky A, Trias E, Ferreira AM, Freeman BA, Cassina P, Barbeito L, Vargas MR, Rubbo H. Electrophilic nitro-fatty acids prevent astrocyte-mediated toxicity to motor neurons in a cell model of familial amyotrophic lateral sclerosis via nuclear factor erythroid 2-related factor activation. Free Radical Biology & Medicine. PMID 27012417 DOI: 10.1016/J.Freeradbiomed.2016.03.013  0.365
2016 Villacorta L, Gao Z, Schopfer FJ, Freeman BA, Chen YE. Nitro-fatty acids in cardiovascular regulation and diseases: characteristics and molecular mechanisms. Frontiers in Bioscience (Landmark Edition). 21: 873-89. PMID 26709810 DOI: 10.2741/4425  0.49
2016 Vitturi DA, Minarrieta L, Salvatore SR, Khoo NK, Jobbagy S, Li L, Woodcock SR, Freeman BA, Villacorta L, Schopfer FJ. Inflammatory Generation and Pro-Resolving Signaling Actions of Conjugated Nitro-Linoleic Acid Free Radical Biology and Medicine. 100: S69. DOI: 10.1016/J.Freeradbiomed.2016.10.179  0.488
2015 Ambrozova G, Martiskova H, Koudelka A, Ravekes T, Rudolph TK, Klinke A, Rudolph V, Freeman BA, Woodcock SR, Kubala L, Pekarova M. Nitro-oleic acid modulates classical and regulatory activation of macrophages and their involvement in pro-fibrotic responses. Free Radical Biology & Medicine. PMID 26620549 DOI: 10.1016/J.Freeradbiomed.2015.11.026  0.428
2015 Rudolph TK, Ravekes T, Klinke A, Friedrichs K, Mollenhauer M, Pekarova M, Ambrozova G, Martiskova H, Kaur JJ, Matthes B, Schwoerer A, Woodcock SR, Kubala L, Freeman BA, Baldus S, et al. Nitrated fatty acids suppress angiotensin II mediated fibrotic remodeling and atrial fibrillation. Cardiovascular Research. PMID 26598510 DOI: 10.1093/Cvr/Cvv254  0.386
2015 Delmastro-Greenwood M, Hughan KS, Vitturi DA, Salvatore SR, Grimes G, Potti G, Shiva S, Schopfer FJ, Gladwin MT, Freeman BA, Gelhaus Wendell S. Nitrite and nitrate-dependent generation of anti-inflammatory fatty acid nitroalkenes. Free Radical Biology & Medicine. 89: 333-341. PMID 26385079 DOI: 10.1016/J.Freeradbiomed.2015.07.149  0.483
2015 Fazzari M, Khoo N, Woodcock SR, Li L, Freeman BA, Schopfer FJ. Generation and esterification of electrophilic fatty acid nitroalkenes in triacylglycerides. Free Radical Biology & Medicine. 87: 113-124. PMID 26066303 DOI: 10.1016/J.Freeradbiomed.2015.05.033  0.507
2015 Vitturi DA, Minarrieta L, Salvatore SR, Postlethwait EM, Fazzari M, Ferrer-Sueta G, Lancaster JR, Freeman BA, Schopfer FJ. Convergence of biological nitration and nitrosation via symmetrical nitrous anhydride. Nature Chemical Biology. 11: 504-10. PMID 26006011 DOI: 10.1038/Nchembio.1814  0.46
2015 Wendell SG, Golin-Bisello F, Wenzel S, Sobol RW, Holguin F, Freeman BA. 15-Hydroxyprostaglandin dehydrogenase generation of electrophilic lipid signaling mediators from hydroxy ω-3 fatty acids. The Journal of Biological Chemistry. 290: 5868-80. PMID 25586183 DOI: 10.1074/Jbc.M114.635151  0.509
2015 Snyder NW, Golin-Bisello F, Gao Y, Blair IA, Freeman BA, Wendell SG. 15-Oxoeicosatetraenoic acid is a 15-hydroxyprostaglandin dehydrogenase-derived electrophilic mediator of inflammatory signaling pathways. Chemico-Biological Interactions. 234: 144-53. PMID 25450232 DOI: 10.1016/J.Cbi.2014.10.029  0.487
2015 Wendell SG, Golin-Bisello F, Wenzel S, Sobol RW, Holguin F, Freeman BA. 15-Hydroxyprostaglandin dehydrogenase generation of electrophilic lipid signaling mediators from hydroxy ω-3 fatty acids Journal of Biological Chemistry. 290: 5868-5880. DOI: 10.1074/jbc.M114.635151  0.318
2015 Fazzari M, Vitturi D, Woodcock SR, Kelley EE, Freeman BA, Schopfer FJ. Gastric Generation of Active Nitro-Nitrates: Novel Lipid Intermediates That Form Nitrosating and Electrophilic Species Free Radical Biology and Medicine. 87: S83. DOI: 10.1016/J.Freeradbiomed.2015.10.219  0.312
2015 Charles R, Freeman B, Eaton P. Nitro-Oleic Acid Inhibits Soluble Epoxide Hydrolase Via Adduction at Cys521 to Provide Cardioprotection Against Ischemia and Reperfusion Injury Free Radical Biology and Medicine. 87: S48. DOI: 10.1016/J.Freeradbiomed.2015.10.125  0.344
2015 Vitturi DA, Minarrieta L, Villacorta L, Salvatore SR, Jobbagy S, Groomes P, Woodcock SR, Li L, Khoo NK, Freeman BA, Schopfer FJ. Regulation of Inflammatory Responses by Conjugated Linoleic Acid Nitration Free Radical Biology and Medicine. 87: S44-S45. DOI: 10.1016/J.Freeradbiomed.2015.10.118  0.374
2014 Zhang X, Beckel JM, Daugherty SL, Wang T, Woodcock SR, Freeman BA, de Groat WC. Activation of TRPC channels contributes to OA-NO2-induced responses in guinea-pig dorsal root ganglion neurons. The Journal of Physiology. 592: 4297-312. PMID 25128576 DOI: 10.1113/Jphysiol.2014.271783  0.301
2014 Charles RL, Rudyk O, Prysyazhna O, Kamynina A, Yang J, Morisseau C, Hammock BD, Freeman BA, Eaton P. Protection from hypertension in mice by the Mediterranean diet is mediated by nitro fatty acid inhibition of soluble epoxide hydrolase. Proceedings of the National Academy of Sciences of the United States of America. 111: 8167-72. PMID 24843165 DOI: 10.1073/Pnas.1402965111  0.426
2014 Cipollina C, Salvatore SR, Muldoon MF, Freeman BA, Schopfer FJ. Generation and dietary modulation of anti-inflammatory electrophilic omega-3 fatty acid derivatives. Plos One. 9: e94836. PMID 24736647 DOI: 10.1371/Journal.Pone.0094836  0.424
2014 Schopfer FJ, Freeman BA, Khoo NKH. Nitro-oleic acid and epoxyoleic acid are not altered in obesity and type 2 diabetes: Reply Cardiovascular Research. 102: 518. PMID 24562767 DOI: 10.1093/Cvr/Cvu042  0.344
2014 Klinke A, Möller A, Pekarova M, Ravekes T, Friedrichs K, Berlin M, Scheu KM, Kubala L, Kolarova H, Ambrozova G, Schermuly RT, Woodcock SR, Freeman BA, Rosenkranz S, Baldus S, et al. Protective effects of 10-nitro-oleic acid in a hypoxia-induced murine model of pulmonary hypertension American Journal of Respiratory Cell and Molecular Biology. 51: 155-162. PMID 24521348 DOI: 10.1165/Rcmb.2013-0063Oc  0.381
2014 Fazzari M, Trostchansky A, Schopfer FJ, Salvatore SR, Sánchez-Calvo B, Vitturi D, Valderrama R, Barroso JB, Radi R, Freeman BA, Rubbo H. Olives and olive oil are sources of electrophilic fatty acid nitroalkenes. Plos One. 9: e84884. PMID 24454759 DOI: 10.1371/Journal.Pone.0084884  0.64
2014 Kelley EE, Baust J, Bonacci G, Golin-Bisello F, Devlin JE, St. Croix CM, Watkins SC, Gor S, Cantu-Medellin N, Weidert ER, Frisbee JC, Gladwin MT, Champion HC, Freeman BA, Khoo NKH. Fatty acid nitroalkenes ameliorate glucose intolerance and pulmonary hypertension in high-fat diet-induced obesity Cardiovascular Research. 101: 352-363. PMID 24385344 DOI: 10.1093/Cvr/Cvt341  0.379
2014 Woodcock SR, Salvatore SR, Bonacci G, Schopfer FJ, Freeman BA. Biomimetic nitration of conjugated linoleic acid: formation and characterization of naturally occurring conjugated nitrodienes. The Journal of Organic Chemistry. 79: 25-33. PMID 24350701 DOI: 10.1021/Jo4021562  0.436
2014 Turell L, Botti H, Bonilla L, Torres MJ, Schopfer F, Freeman BA, Armas L, Ricciardi A, Alvarez B, Radi R. HPLC separation of human serum albumin isoforms based on their isoelectric points. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 944: 144-51. PMID 24316526 DOI: 10.1016/J.Jchromb.2013.11.019  0.57
2014 Zhang X, Koronowski KB, Li L, Freeman BA, Woodcock S, de Groat WC. Nitro-oleic acid desensitizes TRPA1 and TRPV1 agonist responses in adult rat DRG neurons. Experimental Neurology. 251: 12-21. PMID 24212047 DOI: 10.1016/J.Expneurol.2013.10.020  0.362
2014 Awwad K, Steinbrink SD, Frömel T, Lill N, Isaak J, Häfner AK, Roos J, Hofmann B, Heide H, Geisslinger G, Steinhilber D, Freeman BA, Maier TJ, Fleming I. Electrophilic fatty acid species inhibit 5-lipoxygenase and attenuate sepsis-induced pulmonary inflammation. Antioxidants & Redox Signaling. 20: 2667-80. PMID 24206143 DOI: 10.1089/ars.2013.5473  0.404
2014 Delmastro-Greenwood M, Freeman BA, Wendell SG. Redox-dependent anti-inflammatory signaling actions of unsaturated fatty acids Annual Review of Physiology. 76: 79-105. PMID 24161076 DOI: 10.1146/Annurev-Physiol-021113-170341  0.483
2014 Fazzari M, Trostchansky A, Schopfer FJ, Salvatore SR, Sánchez-Calvo B, Vitturi D, Valderrama R, Barroso JB, Radi R, Freeman BA, Rubbo H. Detection of NO 2 -OA-cysteine adducts in fresh olives. Plos One. DOI: 10.1371/Journal.Pone.0084884.G004  0.464
2014 Fazzari M, Trostchansky A, Schopfer FJ, Salvatore SR, Sánchez-Calvo B, Vitturi D, Valderrama R, Barroso JB, Radi R, Freeman BA, Rubbo H. NO 2 -OA generation from EVOO by in vitro digestion modeling. Plos One. DOI: 10.1371/Journal.Pone.0084884.G003  0.456
2014 Fazzari M, Trostchansky A, Schopfer FJ, Salvatore SR, Sánchez-Calvo B, Vitturi D, Valderrama R, Barroso JB, Radi R, Freeman BA, Rubbo H. Identification of specific NO 2 -LA and NO 2 -cLA regio-isomers in EVOO by in vitro digestion modeling. Plos One. DOI: 10.1371/Journal.Pone.0084884.G002  0.455
2014 Wendell S, Delmastro-Greenwood M, Hughan K, Salvatore S, Vitturi D, Schopfer F, Gladwin M, Freeman B. Nitrite and nitrate-dependent generation of fatty acid nitroalkenes Nitric Oxide. 42: 105. DOI: 10.1016/J.Niox.2014.09.023  0.409
2013 Vitturi DA, Chen CS, Woodcock SR, Salvatore SR, Bonacci G, Koenitzer JR, Stewart NA, Wakabayashi N, Kensler TW, Freeman BA, Schopfer FJ. Modulation of nitro-fatty acid signaling: prostaglandin reductase-1 is a nitroalkene reductase. The Journal of Biological Chemistry. 288: 25626-37. PMID 23878198 DOI: 10.1074/Jbc.M113.486282  0.809
2013 Gil M, Graña M, Schopfer FJ, Wagner T, Denicola A, Freeman BA, Alzari PM, Batthyány C, Durán R. Inhibition of Mycobacterium tuberculosis PknG by non-catalytic rubredoxin domain specific modification: reaction of an electrophilic nitro-fatty acid with the Fe-S center. Free Radical Biology & Medicine. 65: 150-61. PMID 23792274 DOI: 10.1016/J.Freeradbiomed.2013.06.021  0.413
2013 Salvatore SR, Vitturi DA, Baker PR, Bonacci G, Koenitzer JR, Woodcock SR, Freeman BA, Schopfer FJ. Characterization and quantification of endogenous fatty acid nitroalkene metabolites in human urine. Journal of Lipid Research. 54: 1998-2009. PMID 23620137 DOI: 10.1194/Jlr.M037804  0.809
2013 Villacorta L, Chang L, Salvatore SR, Ichikawa T, Zhang J, Petrovic-Djergovic D, Jia L, Carlsen H, Schopfer FJ, Freeman BA, Chen YE. Electrophilic nitro-fatty acids inhibit vascular inflammation by disrupting LPS-dependent TLR4 signalling in lipid rafts. Cardiovascular Research. 98: 116-24. PMID 23334216 DOI: 10.1093/Cvr/Cvt002  0.447
2013 Gelhaus Wendell S, Golin-Bisello F, Holguin F, Wenzel S, Freeman Ba. 15-Hydroxyprostaglandin Dehydrogenase Generates Anti-Inflammatory [Omega]-3 Fatty Acid Derivatives Free Radical Biology and Medicine. 65: S148-S149. DOI: 10.1016/J.Freeradbiomed.2013.10.772  0.397
2013 Fazzari M, Khoo N, Woodcock S, Golin- Bisello F, Schopfer FJ, Freeman BA. Metabolic Fate of Endogenous and Exogenously-Administered Electrophilic Fatty Acid Nitroalkenes: the Formation and Actions of Nitro-Fatty Acid-Containing Complex Lipids Free Radical Biology and Medicine. 65: S142. DOI: 10.1016/J.Freeradbiomed.2013.10.752  0.412
2013 Vitturi DA, Salvatore SR, Minarrieta L, Cantu-Medellin N, Ferreira AM, Kelley EE, Freeman BA, Schopfer FJ. Symmetric N2O3 Formation from Nitric Oxide Oxidation: Evidence from Nitration and S-Nitrosation of Biomolecules in the Presence of Isotopically Labeled Sodium Nitrite Free Radical Biology and Medicine. 65: S94. DOI: 10.1016/J.Freeradbiomed.2013.10.623  0.404
2013 Klinke A, Möller A, Ravekes T, Pekarova M, Friedrichs K, Schermuly RT, Kubala L, Kolarova H, Woodcock SR, Freeman BA, Baldus S, Rudolph V, Rudolph T. Protective Effects of Nitro-Fatty Acids in a Hypoxia-Induced Murine Model of Pulmonary Hypertension Free Radical Biology and Medicine. 65: S81. DOI: 10.1016/J.Freeradbiomed.2013.10.588  0.34
2013 Trostchansky A, Fazzari M, Schopfer F, Salvatore S, Barroso J, Radi R, Freeman B, Rubbo H. OLIVES AND OLIVE OIL AS A SOURCE OF ELECTROPHILIC LIPID SIGNALING MEDIATORS Free Radical Biology and Medicine. 65: S3. DOI: 10.1016/J.Freeradbiomed.2013.10.396  0.488
2012 Bonacci G, Baker PR, Salvatore SR, Shores D, Khoo NK, Koenitzer JR, Vitturi DA, Woodcock SR, Golin-Bisello F, Cole MP, Watkins S, St Croix C, Batthyany CI, Freeman BA, Schopfer FJ. Conjugated linoleic acid is a preferential substrate for fatty acid nitration. The Journal of Biological Chemistry. 287: 44071-82. PMID 23144452 DOI: 10.1074/Jbc.M112.401356  0.81
2012 Hammond VJ, Morgan AH, Lauder S, Thomas CP, Brown S, Freeman BA, Lloyd CM, Davies J, Bush A, Levonen AL, Kansanen E, Villacorta L, Chen YE, Porter N, Garcia-Diaz YM, et al. Novel keto-phospholipids are generated by monocytes and macrophages, detected in cystic fibrosis, and activate peroxisome proliferator-activated receptor-γ. The Journal of Biological Chemistry. 287: 41651-66. PMID 23060450 DOI: 10.1074/Jbc.M112.405407  0.441
2012 Nishida M, Sawa T, Kitajima N, Ono K, Inoue H, Ihara H, Motohashi H, Yamamoto M, Suematsu M, Kurose H, Van Der Vliet A, Freeman BA, Shibata T, Uchida K, Kumagai Y, et al. Hydrogen sulfide anion regulates redox signaling via electrophile sulfhydration Nature Chemical Biology. 8: 714-724. PMID 22772154 DOI: 10.1038/Nchembio.1018  0.426
2012 Khoo NK, Cantu-Medellin N, Devlin JE, St Croix CM, Watkins SC, Fleming AM, Champion HC, Mason RP, Freeman BA, Kelley EE. Obesity-induced tissue free radical generation: an in vivo immuno-spin trapping study. Free Radical Biology & Medicine. 52: 2312-9. PMID 22564528 DOI: 10.1016/J.Freeradbiomed.2012.04.011  0.35
2012 Fukuto JM, Carrington SJ, Tantillo DJ, Harrison JG, Ignarro LJ, Freeman BA, Chen A, Wink DA. Small molecule signaling agents: The integrated chemistry and biochemistry of nitrogen oxides, oxides of carbon, dioxygen, hydrogen sulfide, and their derived species Chemical Research in Toxicology. 25: 769-793. PMID 22263838 DOI: 10.1021/Tx2005234  0.341
2012 Freeman BA. Formation and signaling actions of electrophilic fatty acid derivatives Nitric Oxide. 27: S7-S8. DOI: 10.1016/J.Niox.2012.04.029  0.507
2012 Rubbo H, Trostchansky A, Fazzari M, Schopfer F, Barroso JB, Radi R, Freeman BA. Detection of Nitrated Fatty Acids in Olives and Olive Oils Free Radical Biology and Medicine. 53. DOI: 10.1016/J.Freeradbiomed.2012.10.513  0.511
2012 Gil M, Denicola A, Batthyany C, Schopfer F, Freeman B, Alzari P, Durán R. Nitroalkene Oleic Acid Irreversibly Inhibited Mycobacterium Tuberculosis PknG by Electrophilic Attack to Cysteins in the Non-Catalytic Rubredoxin Domain Free Radical Biology and Medicine. 53: S147. DOI: 10.1016/J.Freeradbiomed.2012.10.397  0.325
2012 Vitturi DA, Chen C, Woodcock SR, Stewart N, Wakabayashi N, Salvatore SR, Bonacci GR, Koenitzer JR, Kensler TW, Schopfer FJ, Freeman BA. Modulation of Nitroalkene Signaling by a Novel Nitroalkene Reductase Activity Free Radical Biology and Medicine. 53: S121. DOI: 10.1016/J.Freeradbiomed.2012.10.299  0.733
2012 Ravekes T, Klinke A, Hansen A, Freeman B, Rudolph V, Baldus S, Rudolph TK. Nitrated Fatty Acids Alleviate Dilative Cardiomyopathy in MLP-Deficient Mice Free Radical Biology and Medicine. 53: S77-S78. DOI: 10.1016/J.Freeradbiomed.2012.10.232  0.339
2012 Gor S, Kelley EE, Baust J, Bonnaci GR, Golin-Bisello F, Cantú-Medellín N, Devlin J, St Croix CM, Watkins SC, Champion HC, Freeman BA, Khoo NK. Inhibition of Obesity-Induced Pulmonary Arterial Hypertension by Electrophilic Fatty Acids Free Radical Biology and Medicine. 53: S96. DOI: 10.1016/J.Freeradbiomed.2012.10.174  0.31
2011 Bonacci G, Asciutto EK, Woodcock SR, Salvatore SR, Freeman BA, Schopfer FJ. Gas-phase fragmentation analysis of nitro-fatty acids. Journal of the American Society For Mass Spectrometry. 22: 1534-51. PMID 21953257 DOI: 10.1007/S13361-011-0185-X  0.413
2011 Schopfer FJ, Cipollina C, Freeman BA. Formation and signaling actions of electrophilic lipids Chemical Reviews. 111: 5997-6021. PMID 21928855 DOI: 10.1021/Cr200131E  0.391
2011 Shores DR, Binion DG, Freeman BA, Baker PR. New insights into the role of fatty acids in the pathogenesis and resolution of inflammatory bowel disease. Inflammatory Bowel Diseases. 17: 2192-204. PMID 21910181 DOI: 10.1002/Ibd.21560  0.386
2011 Guo CJ, Schopfer FJ, Gonzales L, Wang P, Freeman BA, Gow AJ. Atypical PKCζ transduces electrophilic fatty acid signaling in pulmonary epithelial cells. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 25: 366-72. PMID 21871968 DOI: 10.1016/J.Niox.2011.07.003  0.46
2011 Artim DE, Bazely F, Daugherty SL, Sculptoreanu A, Koronowski KB, Schopfer FJ, Woodcock SR, Freeman BA, de Groat WC. Nitro-oleic acid targets transient receptor potential (TRP) channels in capsaicin sensitive afferent nerves of rat urinary bladder Experimental Neurology. 232: 90-99. PMID 21867704 DOI: 10.1016/J.Expneurol.2011.08.007  0.419
2011 Al Ghouleh I, Khoo NKH, Knaus UG, Griendling KK, Touyz RM, Thannickal VJ, Barchowsky A, Nauseef WM, Kelley EE, Bauer PM, Darley-Usmar V, Shiva S, Cifuentes-Pagano E, Freeman BA, Gladwin MT, et al. Oxidases and peroxidases in cardiovascular and lung disease: New concepts in reactive oxygen species signaling Free Radical Biology and Medicine. 51: 1271-1288. PMID 21722728 DOI: 10.1016/J.Freeradbiomed.2011.06.011  0.407
2011 Malik UZ, Hundley NJ, Romero G, Radi R, Freeman BA, Tarpey MM, Kelley EE. Febuxostat inhibition of endothelial-bound XO: Implications for targeting vascular ROS production Free Radical Biology and Medicine. 51: 179-184. PMID 21554948 DOI: 10.1016/J.Freeradbiomed.2011.04.004  0.564
2011 Bonacci G, Schopfer FJ, Batthyany CI, Rudolph TK, Rudolph V, Khoo NKH, Kelley EE, Freeman BA. Electrophilic fatty acids regulate matrix metalloproteinase activity and expression Journal of Biological Chemistry. 286: 16074-16081. PMID 21454668 DOI: 10.1074/Jbc.M111.225029  0.383
2011 Kansanen E, Bonacci G, Schopfer FJ, Kuosmanen SM, Tong KI, Leinonen H, Woodcock SR, Yamamoto M, Carlberg C, Ylä-Herttuala S, Freeman BA, Levonen AL. Electrophilic nitro-fatty acids activate NRF2 by a KEAP1 cysteine 151-independent mechanism. The Journal of Biological Chemistry. 286: 14019-27. PMID 21357422 DOI: 10.1074/Jbc.M110.190710  0.494
2011 Tsujita T, Li L, Nakajima H, Iwamoto N, Nakajima-Takagi Y, Ohashi K, Kawakami K, Kumagai Y, Freeman BA, Yamamoto M, Kobayashi M. Nitro-fatty acids and cyclopentenone prostaglandins share strategies to activate the Keap1-Nrf2 system: A study using green fluorescent protein transgenic zebrafish Genes to Cells. 16: 46-57. PMID 21143560 DOI: 10.1111/J.1365-2443.2010.01466.X  0.45
2011 Borniquel S, Jädert C, Freeman BA, Lundberg JO. P14. Dietary nitrite and oleic acid attenuate colonic inflammation in experimental colitis Nitric Oxide. 24: S21. DOI: 10.1016/J.Niox.2011.03.245  0.343
2011 Rudolph TK, Ravekes T, Klinke A, Jit-Kaur J, Friedrichs K, Pekarova M, Freeman BA, Rudolph V, Baldus S. Nitrated Fatty Acids Suppress Angiotensin II Mediated Atrial Fibrillation in Mice Free Radical Biology and Medicine. 51: S49. DOI: 10.1016/J.Freeradbiomed.2011.10.125  0.337
2010 Koenitzer JR, Freeman BA. Redox signaling in inflammation: Interactions of endogenous electrophiles and mitochondria in cardiovascular disease Annals of the New York Academy of Sciences. 1203: 45-52. PMID 20716282 DOI: 10.1111/J.1749-6632.2010.05559.X  0.799
2010 Zhang J, Villacorta L, Chang L, Fan Z, Hamblin M, Zhu T, Chen CS, Cole MP, Schopfer FJ, Deng CX, Garcia-Barrio MT, Feng YH, Freeman BA, Chen YE. Nitro-oleic acid inhibits angiotensin II-induced hypertension. Circulation Research. 107: 540-8. PMID 20558825 DOI: 10.1161/Circresaha.110.218404  0.337
2010 Groeger AL, Cipollina C, Cole MP, Woodcock SR, Bonacci G, Rudolph TK, Rudolph V, Freeman BA, Schopfer FJ. Cyclooxygenase-2 generates anti-inflammatory mediators from omega-3 fatty acids. Nature Chemical Biology. 6: 433-41. PMID 20436486 DOI: 10.1038/Nchembio.367  0.829
2010 Sculptoreanu A, Kullmann FA, Artim DE, Bazley FA, Schopfer F, Woodcock S, Freeman BA, De Groat WC. Nitro-oleic acid inhibits firing and activates TRPV1- and TRPA1-mediated inward currents in dorsal root ganglion neurons from adult male rats Journal of Pharmacology and Experimental Therapeutics. 333: 883-895. PMID 20304940 DOI: 10.1124/Jpet.109.163154  0.356
2010 Rudolph TK, Rudolph V, Edreira MM, Cole MP, Bonacci G, Schopfer FJ, Woodcock SR, Franek A, Pekarova M, Khoo NK, Hasty AH, Baldus S, Freeman BA. Nitro-fatty acids reduce atherosclerosis in apolipoprotein E-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 938-45. PMID 20167658 DOI: 10.1161/Atvbaha.109.201582  0.484
2010 Groeger AL, Freeman BA. Signaling actions of electrophiles: Anti-inflammatory therapeutic candidates Molecular Interventions. 10: 39-50. PMID 20124562 DOI: 10.1124/Mi.10.1.7  0.806
2010 Schopfer FJ, Cole MP, Groeger AL, Chen CS, Khoo NK, Woodcock SR, Golin-Bisello F, Motanya UN, Li Y, Zhang J, Garcia-Barrio MT, Rudolph TK, Rudolph V, Bonacci G, Baker PR, ... ... Freeman BA, et al. Covalent peroxisome proliferator-activated receptor gamma adduction by nitro-fatty acids: selective ligand activity and anti-diabetic signaling actions. The Journal of Biological Chemistry. 285: 12321-33. PMID 20097754 DOI: 10.1074/Jbc.M109.091512  0.814
2010 Khoo NKH, Freeman BA. Electrophilic nitro-fatty acids: Anti-inflammatory mediators in the vascular compartment Current Opinion in Pharmacology. 10: 179-184. PMID 20080062 DOI: 10.1016/J.Coph.2009.11.003  0.459
2010 Borniquel S, Jansson EA, Cole MP, Freeman BA, Lundberg JO. Nitrated oleic acid up-regulates PPARgamma and attenuates experimental inflammatory bowel disease. Free Radical Biology & Medicine. 48: 499-505. PMID 19932165 DOI: 10.1016/J.Freeradbiomed.2009.11.014  0.46
2010 Khoo NK, Rudolph V, Cole MP, Golin-Bisello F, Schopfer FJ, Woodcock SR, Batthyany C, Freeman BA. Activation of vascular endothelial nitric oxide synthase and heme oxygenase-1 expression by electrophilic nitro-fatty acids. Free Radical Biology & Medicine. 48: 230-9. PMID 19857569 DOI: 10.1016/J.Freeradbiomed.2009.10.046  0.491
2010 Rudolph V, Rudolph TK, Schopfer FJ, Bonacci G, Woodcock SR, Cole MP, Baker PR, Ramani R, Freeman BA. Endogenous generation and protective effects of nitro-fatty acids in a murine model of focal cardiac ischaemia and reperfusion. Cardiovascular Research. 85: 155-66. PMID 19666678 DOI: 10.1093/Cvr/Cvp275  0.443
2010 Khoo NK, Csanyi G, Bonacci GR, Freeman BA, Kelley EE. Obesity-induced Endothelial Dysfunction and Vascular Oxidative Stress: Contributions of Xanthine Oxidase Free Radical Biology and Medicine. 49: S39. DOI: 10.1016/J.Freeradbiomed.2010.10.078  0.322
2010 Friedrichs K, Schwoerer AP, Rudolph TK, Klinke A, Lau D, Steven D, Freeman BA, Carrier L, Meinertz T, Willems S, Baldus S, Rudolph V. Nitrated Fatty Acids Suppress Ventricular Arrhythmias During Acute Myocardial Ischemia Free Radical Biology and Medicine. 49: S24. DOI: 10.1016/J.Freeradbiomed.2010.10.033  0.327
2010 Cole MP, Freeman BA. Fatty Acid Transduction of Nitric Oxide Signaling. Cyclooxygenases, Lipoxygenases and Nitro-Fatty Acids. Nitric Oxide. 391-414. DOI: 10.1016/B978-0-12-373866-0.00011-3  0.367
2009 Lundberg JO, Gladwin MT, Ahluwalia A, Benjamin N, Bryan NS, Butler A, Cabrales P, Fago A, Feelisch M, Ford PC, Freeman BA, Frenneaux M, Friedman J, Kelm M, Kevil CG, et al. Nitrate and nitrite in biology, nutrition and therapeutics. Nature Chemical Biology. 5: 865-9. PMID 19915529 DOI: 10.1038/Nchembio.260  0.401
2009 Kansanen E, Jyrkkänen HK, Volger OL, Leinonen H, Kivelä AM, Häkkinen SK, Woodcock SR, Schopfer FJ, Horrevoets AJ, Ylä-Herttuala S, Freeman BA, Levonen AL. Nrf2-dependent and -independent responses to nitro-fatty acids in human endothelial cells: Identification of heat shock response as the major pathway activated by nitro-oleic acid Journal of Biological Chemistry. 284: 33233-33241. PMID 19808663 DOI: 10.1074/Jbc.M109.064873  0.432
2009 Rudolph TK, Freeman BA. Transduction of redox signaling by electrophile-protein reactions Science Signaling. 2: re7. PMID 19797270 DOI: 10.1126/Scisignal.290Re7  0.412
2009 Cole MP, Rudolph TK, Khoo NK, Motanya UN, Golin-Bisello F, Wertz JW, Schopfer FJ, Rudolph V, Woodcock SR, Bolisetty S, Ali MS, Zhang J, Chen YE, Agarwal A, Freeman BA, et al. Nitro-fatty acid inhibition of neointima formation after endoluminal vessel injury. Circulation Research. 105: 965-72. PMID 19797175 DOI: 10.1161/Circresaha.109.199075  0.524
2009 Rudolph V, Freeman BA. Cardiovascular consequences when nitric oxide and lipid signaling converge Circulation Research. 105: 511-522. PMID 19745170 DOI: 10.1161/Circresaha.109.202077  0.478
2009 Wright MM, Kim J, Hock TD, Leitinger N, Freeman BA, Agarwal A. Human haem oxygenase-1 induction by nitro-linoleic acid is mediated by cAMP, AP-1 and E-box response element interactions Biochemical Journal. 422: 353-361. PMID 19534727 DOI: 10.1042/Bj20090339  0.371
2009 Schopfer FJ, Batthyany C, Baker PRS, Bonacci G, Cole MP, Rudolph V, Groeger AL, Rudolph TK, Nadtochiy S, Brookes PS, Freeman BA. Detection and quantification of protein adduction by electrophilic fatty acids: mitochondrial generation of fatty acid nitroalkene derivatives Free Radical Biology and Medicine. 46: 1250-1259. PMID 19353781 DOI: 10.1016/J.Freeradbiomed.2008.12.025  0.821
2009 Baker PRS, Schopfer FJ, O'Donnell VB, Freeman BA. Convergence of nitric oxide and lipid signaling: Anti-inflammatory nitro-fatty acids Free Radical Biology and Medicine. 46: 989-1003. PMID 19200454 DOI: 10.1016/J.Freeradbiomed.2008.11.021  0.488
2009 Iles KE, Wright MM, Cole MP, Welty NE, Ware LB, Matthay MA, Schopfer FJ, Baker PRS, Agarwal A, Freeman BA. Fatty acid transduction of nitric oxide signaling: nitrolinoleic acid mediates protective effects through regulation of the ERK pathway Free Radical Biology and Medicine. 46: 866-875. PMID 19133325 DOI: 10.1016/J.Freeradbiomed.2008.12.001  0.401
2009 Villacorta L, Schopfer FJ, Zhang J, Freeman BA, Chen YE. PPARgamma and its ligands: therapeutic implications in cardiovascular disease. Clinical Science (London, England : 1979). 116: 205-18. PMID 19118492 DOI: 10.1042/Cs20080195  0.354
2009 Nadtochiy SM, Baker PRS, Freeman BA, Brookes PS. Mitochondrial nitroalkene formation and mild uncoupling in ischaemic preconditioning: Implications for cardioprotection Cardiovascular Research. 82: 333-340. PMID 19050010 DOI: 10.1093/Cvr/Cvn323  0.351
2009 Rudolph V, Schopfer FJ, Khoo NKH, Rudolph TK, Cole MP, Woodcock SR, Bonacci G, Groeger AL, Golin-Bisello F, Chen CS, Baker PRS, Freeman BA. Nitro-fatty acid metabolome: saturation, desaturation, β-oxidation, and protein adduction Journal of Biological Chemistry. 284: 1461-1473. PMID 19015269 DOI: 10.1074/Jbc.M802298200  0.822
2009 Ferreira AM, Ferrari MI, Trostchansky A, Batthyany C, Souza JM, Alvarez MN, López GV, Baker PR, Schopfer FJ, O'Donnell V, Freeman BA, Rubbo H. Macrophage activation induces formation of the anti-inflammatory lipid cholesteryl-nitrolinoleate. The Biochemical Journal. 417: 223-34. PMID 18671672 DOI: 10.1042/Bj20080701  0.463
2008 Woodcock SR, Freeman BA. A new hammer in the redox toolbox: High-purity peroxynitrite for cell signaling and toxicology studies Chemical Research in Toxicology. 21: 2227-2228. PMID 19053325 DOI: 10.1021/Tx8004136  0.418
2008 Kelley EE, Batthyany CI, Hundley NJ, Woodcock SR, Bonacci G, Del Rio JM, Schopfer FJ, Lancaster JR, Freeman BA, Tarpey MM. Nitro-oleic acid, a novel and irreversible inhibitor of xanthine oxidoreductase. The Journal of Biological Chemistry. 283: 36176-84. PMID 18974051 DOI: 10.1074/Jbc.M802402200  0.504
2008 Rudolph V, Rudolph TK, Schopfer FJ, Bonacci G, Lau D, Szöcs K, Klinke A, Meinertz T, Freeman BA, Baldus S. Bivalirudin decreases NO bioavailability by vascular immobilization of myeloperoxidase Journal of Pharmacology and Experimental Therapeutics. 327: 324-331. PMID 18701766 DOI: 10.1124/Jpet.108.142414  0.34
2008 Li Y, Zhang J, Schopfer FJ, Martynowski D, Garcia-Barrio MT, Kovach A, Suino-Powell K, Baker PRS, Freeman BA, Chen YE, Xu HE. Molecular recognition of nitrated fatty acids by PPARγ Nature Structural and Molecular Biology. 15: 865-867. PMID 18604218 DOI: 10.1038/Nsmb.1447  0.396
2008 Ichikawa T, Zhang J, Chen K, Liu Y, Schopfer FJ, Baker PRS, Freeman BA, Chen YE, Cui T. Nitroalkenes suppress lipopolysaccharide-induced signal transducer and activator of transcription signaling in macrophages: A critical role of mitogen-activated protein kinase phosphatase 1 Endocrinology. 149: 4086-4094. PMID 18467446 DOI: 10.1210/En.2007-1639  0.423
2008 Freeman BA, Baker PRS, Schopfer FJ, Woodcock SR, Napolitano A, D'Ischia M. Nitro-fatty acid formation and signaling Journal of Biological Chemistry. 283: 15515-15519. PMID 18285326 DOI: 10.1074/Jbc.R800004200  0.55
2008 Turell L, Botti H, Carballal S, Ferrer-Sueta G, Souza JM, Durán R, Freeman BA, Radi R, Alvarez B. Reactivity of sulfenic acid in human serum albumin. Biochemistry. 47: 358-67. PMID 18078330 DOI: 10.1021/Bi701520Y  0.575
2008 Cole MP, Rudoph T, Freeman BA, Bauer PM. O49. Nitro-fatty acid inhibition of neointima formation after endoluminal vessel injury Nitric Oxide. 19: 31. DOI: 10.1016/J.Niox.2008.06.050  0.37
2008 Cardinal J, Jeyabalan G, Tsung A, Dhupar R, Freeman B, Geller D. QS396. Nitrated Oleic Acid Is an Anti-Inflammatory Signaling Mediatior in Rat Hepatocytes Journal of Surgical Research. 144: 424-425. DOI: 10.1016/J.Jss.2007.12.652  0.359
2007 Aslan M, Freeman BA. Redox-dependent impairment of vascular function in sickle cell disease Free Radical Biology and Medicine. 43: 1469-1483. PMID 17964418 DOI: 10.1016/J.Freeradbiomed.2007.08.014  0.569
2007 Baker LM, Baker PR, Golin-Bisello F, Schopfer FJ, Fink M, Woodcock SR, Branchaud BP, Radi R, Freeman BA. Nitro-fatty acid reaction with glutathione and cysteine. Kinetic analysis of thiol alkylation by a Michael addition reaction. The Journal of Biological Chemistry. 282: 31085-93. PMID 17720974 DOI: 10.1074/Jbc.M704085200  0.63
2007 Villacorta L, Zhang J, Garcia-Barrio MT, Chen XL, Freeman BA, Chen YE, Cui T. Nitro-linoleic acid inhibits vascular smooth muscle cell proliferation via the Keap1/Nrf2 signaling pathway. American Journal of Physiology. Heart and Circulatory Physiology. 293: H770-6. PMID 17468336 DOI: 10.1152/Ajpheart.00261.2007  0.437
2007 Tórtora V, Quijano C, Freeman B, Radi R, Castro L. Mitochondrial aconitase reaction with nitric oxide, S-nitrosoglutathione, and peroxynitrite: Mechanisms and relative contributions to aconitase inactivation Free Radical Biology and Medicine. 42: 1075-1088. PMID 17349934 DOI: 10.1016/J.Freeradbiomed.2007.01.007  0.549
2007 Carballal S, Alvarez B, Turell L, Botti H, Freeman BA, Radi R. Sulfenic acid in human serum albumin. Amino Acids. 32: 543-51. PMID 17061035 DOI: 10.1007/S00726-006-0430-Y  0.617
2006 Baldus S, Müllerleile K, Chumley P, Steven D, Rudolph V, Lund GK, Staude HJ, Stork A, Köster R, Kähler J, Weiss C, Münzel T, Meinertz T, Freeman BA, Heitzer T. Inhibition of xanthine oxidase improves myocardial contractility in patients with ischemic cardiomyopathy. Free Radical Biology & Medicine. 41: 1282-8. PMID 17015175 DOI: 10.1016/J.Freeradbiomed.2006.07.010  0.327
2006 Cui T, Schopfer FJ, Zhang J, Chen K, Ichikawa T, Baker PRS, Batthyany C, Chacko BK, Feng X, Patel RP, Agarwal A, Freeman BA, Chen YE. Nitrated fatty acids: Endogenous anti-inflammatory signaling mediators Journal of Biological Chemistry. 281: 35686-35698. PMID 16887803 DOI: 10.1074/Jbc.M603357200  0.508
2006 Batthyany C, Schopfer FJ, Baker PR, Durán R, Baker LM, Huang Y, Cerveñansky C, Branchaud BP, Freeman BA. Reversible post-translational modification of proteins by nitrated fatty acids in vivo. The Journal of Biological Chemistry. 281: 20450-63. PMID 16682416 DOI: 10.1074/Jbc.M602814200  0.485
2006 Wright MM, Schopfer FJ, Baker PR, Vidyasagar V, Powell P, Chumley P, Iles KE, Freeman BA, Agarwal A. Fatty acid transduction of nitric oxide signaling: nitrolinoleic acid potently activates endothelial heme oxygenase 1 expression. Proceedings of the National Academy of Sciences of the United States of America. 103: 4299-304. PMID 16537525 DOI: 10.1073/Pnas.0506541103  0.527
2006 Baker LMS, Freeman BA, Aslan M. Protein Targets and Functional Consequences of Tyrosine Nitration in Vascular Disease Redox Proteomics: From Protein Modifications to Cellular Dysfunction and Diseases. 729-786. DOI: 10.1002/0471973122.ch23  0.428
2005 Gladwin MT, Schechter AN, Kim-Shapiro DB, Patel RP, Hogg N, Shiva S, Cannon RO, Kelm M, Wink DA, Espey MG, Oldfield EH, Pluta RM, Freeman BA, Lancaster JR, Feelisch M, et al. The emerging biology of the nitrite anion. Nature Chemical Biology. 1: 308-14. PMID 16408064 DOI: 10.1038/Nchembio1105-308  0.33
2005 Baker PR, Lin Y, Schopfer FJ, Woodcock SR, Groeger AL, Batthyany C, Sweeney S, Long MH, Iles KE, Baker LM, Branchaud BP, Chen YE, Freeman BA. Fatty acid transduction of nitric oxide signaling: multiple nitrated unsaturated fatty acid derivatives exist in human blood and urine and serve as endogenous peroxisome proliferator-activated receptor ligands. The Journal of Biological Chemistry. 280: 42464-75. PMID 16227625 DOI: 10.1074/Jbc.M504212200  0.821
2005 Baldus S, Köster R, Chumley P, Heitzer T, Rudolph V, Ostad MA, Warnholtz A, Staude HJ, Thuneke F, Koss K, Berger J, Meinertz T, Freeman BA, Münzel T. Oxypurinol improves coronary and peripheral endothelial function in patients with coronary artery disease. Free Radical Biology & Medicine. 39: 1184-90. PMID 16214034 DOI: 10.1016/J.Freeradbiomed.2005.06.004  0.317
2005 Schopfer FJ, Baker PR, Giles G, Chumley P, Batthyany C, Crawford J, Patel RP, Hogg N, Branchaud BP, Lancaster JR, Freeman BA. Fatty acid transduction of nitric oxide signaling. Nitrolinoleic acid is a hydrophobically stabilized nitric oxide donor. The Journal of Biological Chemistry. 280: 19289-97. PMID 15764811 DOI: 10.1074/Jbc.M414689200  0.522
2005 Schopfer FJ, Lin Y, Baker PR, Cui T, Garcia-Barrio M, Zhang J, Chen K, Chen YE, Freeman BA. Nitrolinoleic acid: an endogenous peroxisome proliferator-activated receptor gamma ligand. Proceedings of the National Academy of Sciences of the United States of America. 102: 2340-5. PMID 15701701 DOI: 10.1073/Pnas.0408384102  0.476
2005 Lau D, Mollnau H, Eiserich JP, Freeman BA, Daiber A, Gehling UM, Brümmer J, Rudolph V, Münzel T, Heitzer T, Meinertz T, Baldus S. Myeloperoxidase mediates neutrophil activation by association with CD11b/CD18 integrins. Proceedings of the National Academy of Sciences of the United States of America. 102: 431-6. PMID 15625114 DOI: 10.1073/Pnas.0405193102  0.391
2005 Lang JD, Figueroa M, Sanders KD, Aslan M, Liu Y, Chumley P, Freeman BA. Hypercapnia via reduced rate and tidal volume contributes to lipopolysaccharide-induced lung injury. American Journal of Respiratory and Critical Care Medicine. 171: 147-57. PMID 15477499 DOI: 10.1164/Rccm.200302-305Oc  0.53
2004 Baldus S, Heitzer T, Eiserich JP, Lau D, Mollnau H, Ortak M, Petri S, Goldmann B, Duchstein HJ, Berger J, Helmchen U, Freeman BA, Meinertz T, Münzel T. Myeloperoxidase enhances nitric oxide catabolism during myocardial ischemia and reperfusion. Free Radical Biology & Medicine. 37: 902-11. PMID 15304260 DOI: 10.1016/J.Freeradbiomed.2004.06.003  0.321
2004 Alvarez B, Demicheli V, Durán R, Trujillo M, Cerveñansky C, Freeman BA, Radi R. Inactivation of human Cu,Zn superoxide dismutase by peroxynitrite and formation of histidinyl radical. Free Radical Biology & Medicine. 37: 813-22. PMID 15304256 DOI: 10.1016/J.Freeradbiomed.2004.06.006  0.57
2004 Baker PR, Schopfer FJ, Sweeney S, Freeman BA. Red cell membrane and plasma linoleic acid nitration products: synthesis, clinical identification, and quantitation. Proceedings of the National Academy of Sciences of the United States of America. 101: 11577-82. PMID 15273286 DOI: 10.1073/Pnas.0402587101  0.49
2004 Kelley EE, Trostchansky A, Rubbo H, Freeman BA, Radi R, Tarpey MM. Binding of xanthine oxidase to glycosaminoglycans limits inhibition by oxypurinol. The Journal of Biological Chemistry. 279: 37231-4. PMID 15231841 DOI: 10.1074/Jbc.M402077200  0.537
2004 Aslan M, Freeman BA. Oxidant-mediated impairment of nitric oxide signaling in sickle cell disease--mechanisms and consequences. Cellular and Molecular Biology (Noisy-Le-Grand, France). 50: 95-105. PMID 15040433  0.603
2004 White CR, Parks DA, Patel RP, Shelton J, Tarpey MM, Freeman BA, Darley-Usmar VM. L-Arginine inhibits xanthine oxidase-dependent endothelial dysfunction in hypercholesterolemia. Febs Letters. 561: 94-8. PMID 15013757 DOI: 10.1016/S0014-5793(04)00137-1  0.322
2004 Schwartz JH, White CA, Freeman BA. Do we kNOw how HSP90 and eNOS mediate lung injury in sickle cell disease? American Journal of Physiology. Lung Cellular and Molecular Physiology. 286: L701-4. PMID 15003934 DOI: 10.1152/Ajplung.00362.2003  0.305
2004 Botti H, Batthyány C, Trostchansky A, Radi R, Freeman BA, Rubbo H. Peroxynitrite-mediated alpha-tocopherol oxidation in low-density lipoprotein: a mechanistic approach. Free Radical Biology & Medicine. 36: 152-62. PMID 14744627 DOI: 10.1016/J.Freeradbiomed.2003.10.006  0.533
2004 Lang JD, Figueroa M, Chumley P, Aslan M, Hurt J, Tarpey MM, Alvarez B, Radi R, Freeman BA. Albumin and hydroxyethyl starch modulate oxidative inflammatory injury to vascular endothelium. Anesthesiology. 100: 51-8. PMID 14695724 DOI: 10.1097/00000542-200401000-00012  0.679
2004 Castro L, Eiserich JP, Sweeney S, Radi R, Freeman BA. Cytochrome c: a catalyst and target of nitrite-hydrogen peroxide-dependent protein nitration. Archives of Biochemistry and Biophysics. 421: 99-107. PMID 14678790 DOI: 10.1016/J.Abb.2003.08.033  0.558
2004 Schwartz J, Baker PR, Schopfer FJ, Freeman BA. Nitrated Lipids in a Murine Model of Sickle Cell Disease at Baseline. Blood. 104: 3758-3758. DOI: 10.1182/Blood.V104.11.3758.3758  0.39
2003 Schopfer FJ, Baker PR, Freeman BA. NO-dependent protein nitration: a cell signaling event or an oxidative inflammatory response? Trends in Biochemical Sciences. 28: 646-54. PMID 14659696 DOI: 10.1016/J.Tibs.2003.10.006  0.485
2003 Carballal S, Radi R, Kirk MC, Barnes S, Freeman BA, Alvarez B. Sulfenic acid formation in human serum albumin by hydrogen peroxide and peroxynitrite. Biochemistry. 42: 9906-14. PMID 12924939 DOI: 10.1021/Bi027434M  0.616
2003 Gladwin MT, Lancaster JR, Freeman BA, Schechter AN. Nitric oxide's reactions with hemoglobin: a view through the SNO-storm. Nature Medicine. 9: 496-500. PMID 12724752 DOI: 10.1038/Nm0503-496  0.405
2003 Aslan M, Ryan TM, Townes TM, Coward L, Kirk MC, Barnes S, Alexander CB, Rosenfeld SS, Freeman BA. Nitric oxide-dependent generation of reactive species in sickle cell disease. Actin tyrosine induces defective cytoskeletal polymerization. The Journal of Biological Chemistry. 278: 4194-204. PMID 12401783 DOI: 10.1074/Jbc.M208916200  0.601
2002 Lim DG, Sweeney S, Bloodsworth A, White CR, Chumley PH, Krishna NR, Schopfer F, O'Donnell VB, Eiserich JP, Freeman BA. Nitrolinoleate, a nitric oxide-derived mediator of cell function: synthesis, characterization, and vasomotor activity. Proceedings of the National Academy of Sciences of the United States of America. 99: 15941-6. PMID 12444258 DOI: 10.1073/Pnas.232409599  0.826
2002 Aslan M, Freeman BA. Oxidases and oxygenases in regulation of vascular nitric oxide signaling and inflammatory responses. Immunologic Research. 26: 107-18. PMID 12403350 DOI: 10.1385/Ir:26:1-3:107  0.611
2002 Baldus S, Eiserich JP, Brennan ML, Jackson RM, Alexander CB, Freeman BA. Spatial mapping of pulmonary and vascular nitrotyrosine reveals the pivotal role of myeloperoxidase as a catalyst for tyrosine nitration in inflammatory diseases. Free Radical Biology & Medicine. 33: 1010. PMID 12361810 DOI: 10.1016/S0891-5849(02)00993-0  0.339
2002 Coles B, Bloodsworth A, Clark SR, Lewis MJ, Cross AR, Freeman BA, O'Donnell VB. Nitrolinoleate inhibits superoxide generation, degranulation, and integrin expression by human neutrophils: novel antiinflammatory properties of nitric oxide-derived reactive species in vascular cells. Circulation Research. 91: 375-81. PMID 12215485 DOI: 10.1161/01.Res.0000032114.68919.Ef  0.824
2002 Eiserich JP, Baldus S, Brennan ML, Ma W, Zhang C, Tousson A, Castro L, Lusis AJ, Nauseef WM, White CR, Freeman BA. Myeloperoxidase, a leukocyte-derived vascular NO oxidase. Science (New York, N.Y.). 296: 2391-4. PMID 12089442 DOI: 10.1126/Science.1106830  0.372
2002 Coles B, Bloodsworth A, Eiserich JP, Coffey MJ, McLoughlin RM, Giddings JC, Lewis MJ, Haslam RJ, Freeman BA, O'Donnell VB. Nitrolinoleate inhibits platelet activation by attenuating calcium mobilization and inducing phosphorylation of vasodilator-stimulated phosphoprotein through elevation of cAMP. The Journal of Biological Chemistry. 277: 5832-40. PMID 11748216 DOI: 10.1074/Jbc.M105209200  0.795
2002 Denicola A, Batthyány C, Lissi E, Freeman BA, Rubbo H, Radi R. Diffusion of nitric oxide into low density lipoprotein. The Journal of Biological Chemistry. 277: 932-6. PMID 11689557 DOI: 10.1074/Jbc.M106589200  0.552
2002 Lim DG, Chumley PH, Sweeney S, Freeman BA. Nitrolinoleate - An Oxidized Lipid Transducer of Nitric Oxide Signaling: Synthesis, Characterization and Biological Activity Anesthesiology. 96: A633. DOI: 10.1097/00000542-200209002-00633  0.444
2001 Aslan M, Ryan TM, Adler B, Townes TM, Parks DA, Thompson JA, Tousson A, Gladwin MT, Patel RP, Tarpey MM, Batinic-Haberle I, White CR, Freeman BA. Oxygen radical inhibition of nitric oxide-dependent vascular function in sickle cell disease. Proceedings of the National Academy of Sciences of the United States of America. 98: 15215-20. PMID 11752464 DOI: 10.1073/Pnas.221292098  0.574
2001 Baldus S, Eiserich JP, Mani A, Castro L, Figueroa M, Chumley P, Ma W, Tousson A, White CR, Bullard DC, Brennan ML, Lusis AJ, Moore KP, Freeman BA. Endothelial transcytosis of myeloperoxidase confers specificity to vascular ECM proteins as targets of tyrosine nitration. The Journal of Clinical Investigation. 108: 1759-70. PMID 11748259 DOI: 10.1172/Jci12617  0.368
2001 Coffey MJ, Natarajan R, Chumley PH, Coles B, Thimmalapura PR, Nowell M, Kühn H, Lewis MJ, Freeman BA, O'Donnell VB. Catalytic consumption of nitric oxide by 12/15- lipoxygenase: inhibition of monocyte soluble guanylate cyclase activation. Proceedings of the National Academy of Sciences of the United States of America. 98: 8006-11. PMID 11427723 DOI: 10.1073/Pnas.141136098  0.437
2001 Laursen JB, Somers M, Kurz S, McCann L, Warnholtz A, Freeman BA, Tarpey M, Fukai T, Harrison DG. Endothelial regulation of vasomotion in apoE-deficient mice: implications for interactions between peroxynitrite and tetrahydrobiopterin. Circulation. 103: 1282-8. PMID 11238274 DOI: 10.1161/01.Cir.103.9.1282  0.393
2001 Quijano C, Hernandez-Saavedra D, Castro L, McCord JM, Freeman BA, Radi R. Reaction of peroxynitrite with Mn-superoxide dismutase. Role of the metal center in decomposition kinetics and nitration. The Journal of Biological Chemistry. 276: 11631-8. PMID 11152462 DOI: 10.1074/Jbc.M009429200  0.535
2001 O'Donnell VB, Freeman BA. Interactions between nitric oxide and lipid oxidation pathways: Implications for vascular disease Circulation Research. 88: 12-21. PMID 11139468 DOI: 10.1161/01.Res.88.1.12  0.492
2000 Lang JD, Chumley P, Eiserich JP, Estevez A, Bamberg T, Adhami A, Crow J, Freeman BA. Hypercapnia induces injury to alveolar epithelial cells via a nitric oxide-dependent pathway. American Journal of Physiology. Lung Cellular and Molecular Physiology. 279: L994-1002. PMID 11053037 DOI: 10.1152/Ajplung.2000.279.5.L994  0.454
2000 Bloodsworth A, O'Donnell VB, Freeman BA. Nitric oxide regulation of free radical- and enzyme-mediated lipid and lipoprotein oxidation Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 1707-1715. PMID 10894807 DOI: 10.1161/01.Atv.20.7.1707  0.824
2000 Aslan M, Thornley-Brown D, Freeman BA. Reactive species in sickle cell disease Annals of the New York Academy of Sciences. 899: 375-391. PMID 10863554 DOI: 10.1111/J.1749-6632.2000.Tb06201.X  0.61
2000 Bloodsworth A, O'Donnell VB, Batinic-Haberle I, Chumley PH, Hurt JB, Day BJ, Crow JP, Freeman BA. Manganese-porphyrin reactions with lipids and lipoproteins. Free Radical Biology & Medicine. 28: 1017-29. PMID 10832063 DOI: 10.1016/S0891-5849(00)00194-5  0.819
2000 Ballinger SW, Patterson C, Yan CN, Doan R, Burow DL, Young CG, Yakes FM, Van Houten B, Ballinger CA, Freeman BA, Runge MS. Hydrogen peroxide- and peroxynitrite-induced mitochondrial DNA damage and dysfunction in vascular endothelial and smooth muscle cells. Circulation Research. 86: 960-6. PMID 10807868 DOI: 10.1161/01.Res.86.9.960  0.3
2000 Brookes PS, Salinas EP, Darley-Usmar K, Eiserich JP, Freeman BA, Darley-Usmar VM, Anderson PG. Concentration-dependent effects of nitric oxide on mitochondrial permeability transition and cytochrome c release. The Journal of Biological Chemistry. 275: 20474-9. PMID 10791954 DOI: 10.1074/Jbc.M001077200  0.328
2000 Corbacho AM, Nava G, Eiserich JP, Noris G, Macotela Y, Struman I, Martinez De La Escalera G, Freeman BA, Clapp C. Proteolytic cleavage confers nitric oxide synthase inducing activity upon prolactin. The Journal of Biological Chemistry. 275: 13183-6. PMID 10788422 DOI: 10.1074/Jbc.275.18.13183  0.384
2000 Cassina AM, Hodara R, Souza JM, Thomson L, Castro L, Ischiropoulos H, Freeman BA, Radi R. Cytochrome c nitration by peroxynitrite. The Journal of Biological Chemistry. 275: 21409-15. PMID 10770952 DOI: 10.1074/Jbc.M909978199  0.498
2000 Rubbo H, Radi R, Anselmi D, Kirk M, Barnes S, Butler J, Eiserich JP, Freeman BA. Nitric oxide reaction with lipid peroxyl radicals spares α-tocopherol during lipid peroxidation. Greater oxidant protection from the pair nitric oxide/α-tocopherol than α-tocopherol/ascorbate Journal of Biological Chemistry. 275: 10812-10818. PMID 10753874 DOI: 10.1074/Jbc.275.15.10812  0.563
1999 Luo X, Christie NA, McLaughlin MA, Belcastro R, Sedlackova L, Cabacungan J, Freeman BA, Tanswell AK. H2O2 mediates O2 toxicity in cultured fetal rat distal lung epithelial cells Free Radical Biology and Medicine. 26: 1357-1368. PMID 10401598 DOI: 10.1016/S0891-5849(98)00334-7  0.339
1999 O'Donnell VB, Taylor KB, Parthasarathy S, Kühn H, Koesling D, Friebe A, Bloodsworth A, Darley-Usmar VM, Freeman BA. 15-Lipoxygenase catalytically consumes nitric oxide and impairs activation of guanylate cyclase Journal of Biological Chemistry. 274: 20083-20091. PMID 10400618 DOI: 10.1074/Jbc.274.29.20083  0.822
1999 Tarpey MM, White CR, Suarez E, Richardson G, Radi R, Freeman BA. Chemiluminescent detection of oxidants in vascular tissue: Lucigenin but not coelenterazine enhances superoxide formation Circulation Research. 84: 1203-1211. PMID 10347095 DOI: 10.1161/01.Res.84.10.1203  0.58
1999 Eiserich JP, Estevez AG, Bamberg TV, Yao Zu Ye, Chumley PH, Beckman JS, Freeman BA. Microtubule dysfunction by posttranslational nitrotyrosination of α- tubulin: A nitric oxide-dependent mechanism of cellular injury Proceedings of the National Academy of Sciences of the United States of America. 96: 6365-6370. PMID 10339593 DOI: 10.1073/Pnas.96.11.6365  0.347
1999 Patel RP, McAndrew J, Sellak H, White CR, Jo H, Freeman BA, Darley-Usmar VM. Biological aspects of reactive nitrogen species Biochimica Et Biophysica Acta - Bioenergetics. 1411: 385-400. PMID 10320671 DOI: 10.1016/S0005-2728(99)00028-6  0.388
1999 Houston M, Estevez A, Chumley P, Aslan M, Marklund S, Parks DA, Freeman BA. Binding of xanthine oxidase to vascular endothelium: Kinetic characterization and oxidative impairment of nitric oxide-dependent signaling Journal of Biological Chemistry. 274: 4985-4994. PMID 9988743 DOI: 10.1074/Jbc.274.8.4985  0.582
1999 Radi R, Denicola A, Freeman BA. Peroxynitrite reactions with carbon dioxide-bicarbonate. Methods in Enzymology. 301: 353-67. PMID 9919584 DOI: 10.1016/S0076-6879(99)01099-X  0.588
1999 O'Donnell VB, Eiserich JP, Chumley PH, Jablonsky MJ, Krishna NR, Kirk M, Barnes S, Darley-Usmar VM, Freeman BA. Nitration of unsaturated fatty acids by nitric oxide-derived reactive nitrogen species peroxynitrite, nitrous acid, nitrogen dioxide, and nitronium ion Chemical Research in Toxicology. 12: 83-92. PMID 9894022 DOI: 10.1021/Tx980207U  0.462
1999 Alvarez B, Ferrer-Sueta G, Freeman BA, Radi R. Kinetics of peroxynitrite reaction with amino acids and human serum albumin. The Journal of Biological Chemistry. 274: 842-8. PMID 9873023 DOI: 10.1016/S0891-5849(98)90204-0  0.587
1999 Sakawi Y, Parks D, Tarpey M, Chen YF, Connor M, Freeman B, Chestnut D. Role of nitric oxide in an endotoxin-mediated rodent model of preeclampsia Anesthesiology. 90: 3A. DOI: 10.1097/00000542-199904001-00003  0.396
1998 O'Donnell VB, Eiserich JP, Bloodsworth A, Chumley PH, Kirk M, Barnes S, Darley-Usmar VM, Freeman BA. Nitration of unsaturated fatty acids by nitric oxide-derived reactive species Methods in Enzymology. 301: 454-470. PMID 9919594 DOI: 10.1016/S0076-6879(99)01109-X  0.825
1998 Houston M, Chumley P, Radi R, Rubbo H, Freeman BA. Xanthine oxidase reaction with nitric oxide and peroxynitrite Archives of Biochemistry and Biophysics. 355: 1-8. PMID 9647660 DOI: 10.1006/Abbi.1998.0675  0.644
1998 Nielsen VG, Baird MS, McAdams ML, Freeman BA. Desflurane increases pulmonary alveolar-capillary membrane permeability after aortic occlusion-reperfusion in rabbits: evidence of oxidant-mediated lung injury. Anesthesiology. 88: 1524-34. PMID 9637647 DOI: 10.1097/00000542-199806000-00017  0.342
1998 Trujillo M, Alvarez MN, Peluffo G, Freeman BA, Radi R. Xanthine oxidase-mediated decomposition of S-nitrosothiols Journal of Biological Chemistry. 273: 7828-7834. PMID 9525875 DOI: 10.1074/Jbc.273.14.7828  0.579
1998 Eiserich JP, Hristova M, Cross CE, Jones AD, Freeman BA, Halliwell B, Van Der Vliet A. Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils Nature. 391: 393-397. PMID 9450756 DOI: 10.1038/34923  0.51
1998 Tan S, McAdams M, Royall J, Freeman BA, Parks DA. Endothelial injury from a circulating mediator following rat liver ischemia. Free Radical Biology & Medicine. 24: 427-34. PMID 9438555 DOI: 10.1016/S0891-5849(97)00274-8  0.304
1998 Rubbo H, Freeman BA. Nitric Oxide Regulation of Superoxide and Peroxynitrite-Dependent Reactions Advances in Molecular and Cell Biology. 25: 135-155. DOI: 10.1016/S1569-2558(08)60035-1  0.463
1998 Rubbo H, Batthyány C, Anselmi D, Freeman BA, Radi R. Nitric oxide inhibition of spontaneous chemiluminescence during LDL oxidation Free Radical Biology and Medicine. 25: S66. DOI: 10.1016/S0891-5849(98)90207-6  0.58
1998 O'Donnell V, Bloodsworth A, Eiserich J, Chumley P, Jablonsky M, Krishna N, Kirk M, Barnes S, Darley-Usmar V, Freeman B. Nitration of unsaturated fatty acids by nitric oxide-derived reactive nitrogen species Free Radical Biology and Medicine. 25: S64. DOI: 10.1016/S0891-5849(98)90198-8  0.824
1998 O'Donnell V, Taylor K, Parthasarathy S, Kühn H, Darley-Usmar V, Freeman B. Turnover-dependent consumption of nitric oxide by 15-lipoxygenase: Modulation of nitric oxide signalling and 15-lipoxygenase activity Free Radical Biology and Medicine. 25: S64. DOI: 10.1016/S0891-5849(98)90197-6  0.49
1997 O'Donnell VB, Chumley PH, Hogg N, Bloodsworth A, Darley-Usmar VM, Freeman BA. Nitric oxide inhibition of lipid peroxidation: Kinetics of reaction with lipid peroxyl radicals and comparison with α-tocopherol Biochemistry. 36: 15216-15223. PMID 9398249 DOI: 10.1021/Bi971891Z  0.811
1997 Radi R, Rubbo H, Bush K, Freeman BA. Xanthine oxidase binding to glycosaminoglycans: Kinetics and superoxide dismutase interactions of immobilized xanthine oxidase-heparin complexes Archives of Biochemistry and Biophysics. 339: 125-135. PMID 9056242 DOI: 10.1006/Abbi.1996.9844  0.516
1997 Gutierrez HH, Nieves B, Chumley P, Rivera A, Freeman BA. Nitric oxide regulation of superoxide-dependent lung injury: oxidant-protective actions of endogenously produced and exogenously administered nitric oxide. Free Radical Biology & Medicine. 21: 43-52. PMID 8791092 DOI: 10.1016/0891-5849(95)02226-0  0.42
1996 Alvarez B, Rubbo H, Kirk M, Barnes S, Freeman BA, Radi R. Peroxynitrite-dependent tryptophan nitration. Chemical Research in Toxicology. 9: 390-6. PMID 8839040 DOI: 10.1021/Tx950133B  0.616
1996 Rubbo H, Darley-Usmar V, Freeman BA. Nitric oxide regulation of tissue free radical injury Chemical Research in Toxicology. 9: 809-820. PMID 8828915 DOI: 10.1021/Tx960037Q  0.432
1996 Münzel T, Kurz S, Rajagopalan S, Thoenes M, Berrington WR, Thompson JA, Freeman BA, Harrison DG. Hydralazine prevents nitroglycerin tolerance by inhibiting activation of a membrane-bound NADH oxidase: A new action for an old drug Journal of Clinical Investigation. 98: 1465-1470. PMID 8823313 DOI: 10.1172/Jci118935  0.326
1996 Denicola A, Freeman BA, Trujillo M, Radi R. Peroxynitrite reaction with carbon dioxide/bicarbonate: kinetics and influence on peroxynitrite-mediated oxidations. Archives of Biochemistry and Biophysics. 333: 49-58. PMID 8806753 DOI: 10.1006/Abbi.1996.0363  0.572
1996 Rubbo H, Freeman BA. Nitric oxide regulation of lipid oxidation reactions: Formation and analysis of nitrogen-containing oxidized lipid derivatives Methods in Enzymology. 269: 385-395. PMID 8791667 DOI: 10.1016/S0076-6879(96)69039-9  0.48
1996 White CR, Darley-Usmar V, Berrington WR, McAdams M, Gore JZ, Thompson JA, Parks DA, Tarpey MM, Freeman BA. Circulating plasma xanthine oxidase contributes to vascular dysfunction in hypercholesterolemic rabbits. Proceedings of the National Academy of Sciences of the United States of America. 93: 8745-9. PMID 8710942 DOI: 10.1073/Pnas.93.16.8745  0.364
1996 Rubbo H, Tarpey M, Freeman BA. Nitric oxide and reactive oxygen species in vascular injury. Biochemical Society Symposium. 61: 33-45. PMID 8660401 DOI: 10.1042/Bss0610033  0.467
1996 Freeman BA, White CR, Gutierrez H, Paler-Martínez A, Tarpey MM, Rubbo H. Oxygen radical-nitric oxide reactions in vascular diseases. Advances in Pharmacology (San Diego, Calif.). 34: 45-69. PMID 8562451 DOI: 10.1016/S1054-3589(08)61080-7  0.446
1996 Rubbo H, Parthasarathy S, Barnes S, Kirk M, Kalyanaraman B, Freeman BA. Nitric oxide inhibition of lipoxygenase-dependent liposome and low-density lipoprotein oxidation: termination of radical chain propagation reactions and formation of nitrogen-containing oxidized lipid derivatives. Archives of Biochemistry and Biophysics. 324: 15-25. PMID 7503550 DOI: 10.1006/Abbi.1995.9935  0.498
1995 Briscoe P, Caniggia I, Graves A, Benson B, Huang L, Tanswell AK, Freeman BA. Delivery of superoxide dismutase to pulmonary epithelium via pH-sensitive liposomes. The American Journal of Physiology. 268: L374-80. PMID 7900818 DOI: 10.1152/Ajplung.1995.268.3.L374  0.322
1995 Münzel T, Sayegh H, Freeman BA, Tarpey MM, Harrison DG. Evidence for enhanced vascular superoxide anion production in nitrate tolerance. A novel mechanism underlying tolerance and cross-tolerance. The Journal of Clinical Investigation. 95: 187-94. PMID 7814613 DOI: 10.1172/Jci117637  0.355
1995 Freeman BA, Gutierrez H, Rubbo H. Nitric oxide: a central regulatory species in pulmonary oxidant reactions. The American Journal of Physiology. 268: L697-8. PMID 7762672 DOI: 10.1152/Ajplung.1995.268.5.L697  0.409
1995 Gutierrez HH, Pitt BR, Schwarz M, Watkins SC, Lowenstein C, Caniggia I, Chumley P, Freeman BA. Pulmonary alveolar epithelial inducible NO synthase gene expression: regulation by inflammatory mediators. The American Journal of Physiology. 268: L501-8. PMID 7534997 DOI: 10.1152/Ajplung.1995.268.3.L501  0.412
1994 White CR, Brock TA, Chang LY, Crapo J, Briscoe P, Ku D, Bradley WA, Gianturco SH, Gore J, Freeman BA. Superoxide and peroxynitrite in atherosclerosis. Proceedings of the National Academy of Sciences of the United States of America. 91: 1044-8. PMID 8302829 DOI: 10.1073/Pnas.91.3.1044  0.445
1994 Paler-Martínez A, Panus PC, Chumley PH, Ryan U, Hardy MM, Freeman BA. Endogenous xanthine oxidase does not significantly contribute to vascular endothelial production of reactive oxygen species. Archives of Biochemistry and Biophysics. 311: 79-85. PMID 8185323 DOI: 10.1006/Abbi.1994.1211  0.389
1994 Freeman B. Free radical chemistry of nitric oxide: Looking at the dark side Chest. 105. PMID 8131620 DOI: 10.1378/Chest.105.3_Supplement.79S  0.401
1994 Christie NA, Slutsky AS, Freeman BA, Tanswell AK. A critical role for thiol, but not ATP, depletion in 95% O2-mediated injury of preterm pneumocytes in vitro. Archives of Biochemistry and Biophysics. 313: 131-8. PMID 8053673 DOI: 10.1006/Abbi.1994.1369  0.325
1994 Tarpey MM, Freeman BA. Nitric oxide and myocardial ischemia Current Opinion in Anaesthesiology. 7: 91-97. DOI: 10.1097/00001503-199402000-00016  0.363
1993 Panus PC, Radi R, Chumley PH, Lillard RH, Freeman BA. Detection of H2O2 release from vascular endothelial cells. Free Radical Biology & Medicine. 14: 217-23. PMID 8425723 DOI: 10.1016/0891-5849(93)90013-K  0.531
1993 Radi R, Cosgrove TP, Beckman JS, Freeman BA. Peroxynitrite-induced luminol chemiluminescence Biochemical Journal. 290: 51-57. PMID 8382481 DOI: 10.1042/Bj2900051  0.575
1993 Radi R, Bush KM, Freeman BA. The role of cytochrome c and mitochondrial catalase in hydroperoxide-induced heart mitochondrial lipid peroxidation. Archives of Biochemistry and Biophysics. 300: 409-15. PMID 8380970 DOI: 10.1006/Abbi.1993.1055  0.529
1993 Tan S, Yokoyama Y, Dickens E, Cash TG, Freeman BA, Parks DA. Xanthine oxidase activity in the circulation of rats following hemorrhagic shock Free Radical Biology and Medicine. 15: 407-414. PMID 8225022 DOI: 10.1016/0891-5849(93)90040-2  0.35
1993 Radi R, Rubbo H, Bush K, Freeman B. Xanthine oxidase interactions with glycosaminoglycans Free Radical Biology and Medicine. 15: 521. DOI: 10.1016/0891-5849(93)90376-6  0.442
1993 Freeman B, Trujillo M, Rubbo H, Radi R. Inhibition of superoxide-dependent toxicity by nitric oxide Free Radical Biology and Medicine. 15: 496. DOI: 10.1016/0891-5849(93)90281-X  0.586
1992 Panus PC, Wright SA, Chumley PH, Radi R, Freeman BA. The contribution of vascular endothelial xanthine dehydrogenase/oxidase to oxygen-mediated cell injury Archives of Biochemistry and Biophysics. 294: 695-702. PMID 1567225 DOI: 10.1016/0003-9861(92)90743-G  0.541
1992 Royall JA, Gwin PD, Parks DA, Freeman BA. Responses of vascular endothelial oxidant metabolism to lipopolysaccharide and tumor necrosis factor-alpha. Archives of Biochemistry and Biophysics. 294: 686-94. PMID 1567224 DOI: 10.1016/0003-9861(92)90742-F  0.437
1991 Radi R, Bush KM, Cosgrove TP, Freeman BA. Reaction of xanthine oxidase-derived oxidants with lipid and protein of human plasma Archives of Biochemistry and Biophysics. 286: 117-125. PMID 1897941 DOI: 10.1016/0003-9861(91)90016-C  0.625
1991 Radi R, Beckman JS, Bush KM, Freeman BA. Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide. Archives of Biochemistry and Biophysics. 288: 481-7. PMID 1654835 DOI: 10.1016/0003-9861(91)90224-7  0.612
1991 Radi R, Turrens JF, Freeman BA. Cytochrome c-catalyzed membrane lipid peroxidation by hydrogen peroxide. Archives of Biochemistry and Biophysics. 288: 118-25. PMID 1654818 DOI: 10.1016/0003-9861(91)90172-F  0.586
1990 Matalon S, Holm BA, Baker RR, Whitfield MK, Freeman BA. Characterization of antioxidant activities of pulmonary surfactant mixtures. Biochimica Et Biophysica Acta. 1035: 121-7. PMID 2393661 DOI: 10.1016/0304-4165(90)90105-6  0.373
1990 Tanswell AK, Olson DM, Freeman BA. Response of fetal rat lung fibroblasts to elevated oxygen concentrations after liposome-mediated augmentation of antioxidant enzymes Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 1044: 269-274. PMID 2344446 DOI: 10.1016/0005-2760(90)90313-M  0.317
1990 Yokoyama Y, Beckman JS, Beckman TK, Wheat JK, Cash TG, Freeman BA, Parks DA. Circulating xanthine oxidase: Potential mediator of ischemic injury American Journal of Physiology - Gastrointestinal and Liver Physiology. 258: G564-G570. PMID 2333969 DOI: 10.1152/Ajpgi.1990.258.4.G564  0.315
1990 Baker RR, Panus PC, Holm BA, Engstrom PC, Freeman BA, Matalon S. Endogenous xanthine oxidase-derived O2 metabolites inhibit surfactant metabolism. The American Journal of Physiology. 259: L328-34. PMID 2221090 DOI: 10.1152/Ajplung.1990.259.4.L328  0.362
1990 Beckman JS, Beckman TW, Chen J, Marshall PA, Freeman BA. Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide Proceedings of the National Academy of Sciences of the United States of America. 87: 1620-1624. PMID 2154753 DOI: 10.1073/Pnas.87.4.1620  0.466
1990 Paler-Martinez A, Panus P, Freeman B. Role of xanthine oxidase in the formation and release of reactive oxygen species from cultured vascular endothelium Free Radical Biology and Medicine. 9: 98. DOI: 10.1016/0891-5849(90)90522-K  0.31
1990 Radi R, Beckman JS, Bush KM, Freeman BA. Sulfhydryl oxidation by peroxynitrite Free Radical Biology and Medicine. 9: 33. DOI: 10.1016/0891-5849(90)90284-P  0.564
1990 TANSWELL K, OLSON D, FREEMAN B. Augmentation of fetal lung cell superoxide dismutase (SOD) and catalase (CAT) activities protects against the lethal effects of elevated O but does not attenuate O-mediated inhibition of growth or increase of prostaglandin synthesis Cell Biology International Reports. 14: 76. DOI: 10.1016/0309-1651(90)90412-R  0.304
1989 Panus PC, Shearer J, Freeman BA. Pulmonary metabolism of reactive oxygen species. Experimental Lung Research. 959-76. PMID 3061793 DOI: 10.3109/01902148809064186  0.357
1989 Hsu CY, Liu TH, Xu J, Hogan EL, Chao J, Sun G, Tai HH, Beckman JS, Freeman BA. Arachidonic acid and its metabolites in cerebral ischemia. Annals of the New York Academy of Sciences. 559: 282-95. PMID 2774402 DOI: 10.1111/J.1749-6632.1989.Tb22616.X  0.333
1989 Beckman JS, Parks DA, Pearson JD, Marshall PA, Freeman BA. A sensitive fluorometric assay for measuring xanthine dehydrogenase and oxidase in tissues Free Radical Biology and Medicine. 6: 607-615. PMID 2753392 DOI: 10.1016/0891-5849(89)90068-3  0.321
1989 White CW, Jackson JH, Abuchowski A, Kazo GM, Mimmack RF, Berger EM, Freeman BA, McCord JM, Repine JE. Polyethylene glycol-attached antioxidant enzymes decrease pulmonary oxygen toxicity in rats. Journal of Applied Physiology (Bethesda, Md. : 1985). 66: 584-90. PMID 2540139 DOI: 10.1152/Jappl.1989.66.2.584  0.315
1989 Matalon S, Beckman JS, Duffey ME, Freeman BA. Oxidant inhibition of epithelial active sodium transport Free Radical Biology and Medicine. 6: 557-564. PMID 2502482 DOI: 10.1016/0891-5849(89)90061-0  0.319
1987 Buckley BJ, Tanswell AK, Freeman BA. Liposome-mediated augmentation of catalase in alveolar type II cells protects against H2O2 injury. Journal of Applied Physiology (Bethesda, Md. : 1985). 63: 359-67. PMID 3040661 DOI: 10.1152/Jappl.1987.63.1.359  0.396
1986 Beckman JS, Minor RL, Freeman BA. Augmentation of antioxidant enzymes in vascular endothelium. Journal of Free Radicals in Biology & Medicine. 2: 359-65. PMID 3598065 DOI: 10.1016/S0748-5514(86)80036-8  0.391
1985 Rosen GM, Freeman BA. Detection of superoxide generated by endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 81: 7269-73. PMID 6095281 DOI: 10.1073/Pnas.81.23.7269  0.396
1981 Freeman BA, Mudd JB. Reaction of ozone with sulfhydryls of human erythrocytes Archives of Biochemistry and Biophysics. 208: 212-220. PMID 7259179 DOI: 10.1016/0003-9861(81)90142-9  0.555
1980 Freeman BA, Lynn WS. Fatty acid secretion and metabolism in 'activated' rabbit alveolar macrophages Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 620: 528-537. PMID 7236656 DOI: 10.1016/0005-2760(80)90145-9  0.32
1979 Freeman BA, Sharman MC, Mudd JB. Reaction of ozone with phospholipid vesicles and human erythrocyte ghosts Archives of Biochemistry and Biophysics. 197: 264-272. PMID 575611 DOI: 10.1016/0003-9861(79)90244-3  0.564
1976 Freeman BA, Sissenstein R, McManus TT, Woodward JE, Lee IM, Mudd JB. Lipid composition and lipid metabolism of Spiroplasma citri Journal of Bacteriology. 125: 946-954. PMID 1254560  0.618
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