| Year |
Citation |
Score |
| 2023 |
Farias Amorim C, Lovins VM, Singh TP, Novais FO, Harris JC, Lago AS, Carvalho LP, Carvalho EM, Beiting DP, Scott P, Grice EA. Multiomic profiling of cutaneous leishmaniasis infections reveals microbiota-driven mechanisms underlying disease severity. Science Translational Medicine. 15: eadh1469. PMID 37851822 DOI: 10.1126/scitranslmed.adh1469 |
0.338 |
|
| 2023 |
Peixoto FC, Zanette DL, Cardoso TM, Nascimento MT, Sanches RCO, Aoki M, Scott P, Oliveira SC, Carvalho EM, Carvalho LP. exosomes activate human macrophages to produce proinflammatory mediators. Frontiers in Immunology. 14: 1256425. PMID 37841240 DOI: 10.3389/fimmu.2023.1256425 |
0.336 |
|
| 2023 |
Singh TP, Farias Amorim C, Lovins VM, Bradley CW, Carvalho LP, Carvalho EM, Grice EA, Scott P. Regulatory T cells control Staphylococcus aureus and disease severity of cutaneous leishmaniasis. The Journal of Experimental Medicine. 220. PMID 37812390 DOI: 10.1084/jem.20230558 |
0.352 |
|
| 2023 |
Sacramento LA, Farias Amorim C, Campos TM, Saldanha M, Arruda S, Carvalho LP, Beiting DP, Carvalho EM, Novais FO, Scott P. NKG2D promotes CD8 T cell-mediated cytotoxicity and is associated with treatment failure in human cutaneous leishmaniasis. Plos Neglected Tropical Diseases. 17: e0011552. PMID 37603573 DOI: 10.1371/journal.pntd.0011552 |
0.359 |
|
| 2023 |
Farias Amorim C, Lovins VM, Singh TP, Novais FO, Harris JC, Lago AS, Carvalho LP, Carvalho EM, Beiting DP, Scott P, Grice EA. The skin microbiome enhances disease through IL-1b and delays healing in cutaneous leishmaniasis patients. Medrxiv : the Preprint Server For Health Sciences. PMID 36798406 DOI: 10.1101/2023.02.02.23285247 |
0.319 |
|
| 2022 |
Weinkopff T, Roys H, Bowlin A, Scott P. Erratum for Weinkopff et al., " Infection Induces Macrophage Vascular Endothelial Growth Factor A Production in an ARNT/HIF-Dependent Manner". Infection and Immunity. 90: e0001922. PMID 35377173 DOI: 10.1128/iai.00019-22 |
0.707 |
|
| 2021 |
Farias Amorim C, O Novais F, Nguyen BT, Nascimento MT, Lago J, Lago AS, Carvalho LP, Beiting DP, Scott P. Localized skin inflammation during cutaneous leishmaniasis drives a chronic, systemic IFN-γ signature. Plos Neglected Tropical Diseases. 15: e0009321. PMID 33793565 DOI: 10.1371/journal.pntd.0009321 |
0.311 |
|
| 2020 |
Scott P. Long-Lived Skin-Resident Memory T Cells Contribute to Concomitant Immunity in Cutaneous Leishmaniasis. Cold Spring Harbor Perspectives in Biology. PMID 32839202 DOI: 10.1101/Cshperspect.A038059 |
0.408 |
|
| 2020 |
Saldanha MG, Pagliari C, Queiroz A, Machado PRL, Carvalho L, Scott P, Carvalho EM, Arruda S. Tissue Damage in Human Cutaneous Leishmaniasis: Correlations Between Inflammatory Cells and Molecule Expression. Frontiers in Cellular and Infection Microbiology. 10: 355. PMID 32766167 DOI: 10.3389/Fcimb.2020.00355 |
0.408 |
|
| 2020 |
Novais FO, Nguyen BT, Scott P. Granzyme B inhibition by tofacitinib blocks pathology induced by CD8 T cells in cutaneous leishmaniasis. The Journal of Investigative Dermatology. PMID 32738245 DOI: 10.1016/J.Jid.2020.07.011 |
0.437 |
|
| 2019 |
Campos TM, Novais FO, Saldanha M, Costa R, Lordelo M, Celestino D, Sampaio C, Tavares N, Arruda S, Machado P, Brodskyn C, Scott P, Carvalho EM, Carvalho LP. Granzyme B Produced by Natural Killer Cells Enhances Inflammatory Response and Contributes to the Immunopathology of Cutaneous Leishmaniasis. The Journal of Infectious Diseases. PMID 31748808 DOI: 10.1093/Infdis/Jiz538 |
0.434 |
|
| 2019 |
Weinkopff T, Roys H, Bowlin A, Scott P. infection induces macrophage VEGF-A production in a ARNT/HIF-dependent manner. Infection and Immunity. PMID 31451620 DOI: 10.1128/Iai.00088-19 |
0.746 |
|
| 2019 |
Carvalho AM, Novais FO, Paixão CS, de Oliveira CI, Lima Machado PR, Carvalho LP, Scott P, Carvalho EM. Glyburide, a NLRP3 inhibitor, decreases inflammatory response and is a candidate to reduce pathology in Leishmania braziliensis infection. The Journal of Investigative Dermatology. PMID 31252034 DOI: 10.1016/J.Jid.2019.05.025 |
0.364 |
|
| 2019 |
Louis L, Clark M, Wise MC, Glennie N, Wong A, Broderick K, Uzonna J, Weiner DB, Scott P. Intradermal synDNA vaccination generates Leishmania specific T cells in the skin and protection against . Infection and Immunity. PMID 31182618 DOI: 10.1128/Iai.00227-19 |
0.367 |
|
| 2019 |
Polari LP, Carneiro PP, Macedo M, Machado PRL, Scott P, Carvalho EM, Bacellar O. Infection Enhances Toll-Like Receptors 2 and 4 Expression and Triggers TNF-α and IL-10 Production in Human Cutaneous Leishmaniasis. Frontiers in Cellular and Infection Microbiology. 9: 120. PMID 31119102 DOI: 10.3389/Fcimb.2019.00120 |
0.413 |
|
| 2018 |
Jašarević E, Howard CD, Morrison K, Misic A, Weinkopff T, Scott P, Hunter C, Beiting D, Bale TL. The maternal vaginal microbiome partially mediates the effects of prenatal stress on offspring gut and hypothalamus. Nature Neuroscience. PMID 29988069 DOI: 10.1038/S41593-018-0182-5 |
0.678 |
|
| 2018 |
Novais FO, Wong AC, Villareal DO, Beiting DP, Scott P. CD8+ T Cells Lack Local Signals To Produce IFN-γ in the Skin during Leishmania Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 29367210 DOI: 10.4049/Jimmunol.1701597 |
0.472 |
|
| 2017 |
Santos D, Campos TM, Saldanha M, Oliveira SC, Nascimento M, Zamboni DS, Machado PR, Arruda S, Scott P, Carvalho EM, Carvalho LP. IL-1β production by intermediate monocytes is associated with immunopathology in cutaneous leishmaniasis. The Journal of Investigative Dermatology. PMID 29246797 DOI: 10.1016/J.Jid.2017.11.029 |
0.399 |
|
| 2017 |
Costa RS, Carvalho LP, Campos TM, Magalhães AS, Passos ST, Schriefer A, Silva JA, Lago E, Paixão CS, Machado P, Scott P, Carvalho EM. Early Cutaneous Leishmaniasis Patients Infected with Leishmania braziliensis Express Increased Inflammatory Responses Following Antimony Therapy. The Journal of Infectious Diseases. PMID 29216363 DOI: 10.1093/Infdis/Jix627 |
0.308 |
|
| 2017 |
Gimblet C, Meisel JS, Loesche MA, Cole SD, Horwinski J, Novais FO, Misic AM, Bradley CW, Beiting DP, Rankin SC, Carvalho LP, Carvalho EM, Scott P, Grice EA. Cutaneous Leishmaniasis Induces a Transmissible Dysbiotic Skin Microbiota that Promotes Skin Inflammation. Cell Host & Microbe. PMID 28669672 DOI: 10.1016/J.Chom.2017.06.006 |
0.34 |
|
| 2017 |
Glennie ND, Volk SW, Scott P. Skin-resident CD4+ T cells protect against Leishmania major by recruiting and activating inflammatory monocytes. Plos Pathogens. 13: e1006349. PMID 28419151 DOI: 10.1371/Journal.Ppat.1006349 |
0.406 |
|
| 2017 |
Novais FO, Carvalho AM, Clark ML, Carvalho LP, Beiting DP, Brodsky IE, Carvalho EM, Scott P. CD8+ T cell cytotoxicity mediates pathology in the skin by inflammasome activation and IL-1β production. Plos Pathogens. 13: e1006196. PMID 28192528 DOI: 10.1371/Journal.Ppat.1006196 |
0.447 |
|
| 2017 |
Saldanha MG, Queiroz A, Machado PR, de Carvalho LP, Scott P, de Carvalho Filho EM, Arruda S. Characterization of the Histopathologic Features in Patients in the Early and Late Phases of Cutaneous Leishmaniasis. The American Journal of Tropical Medicine and Hygiene. PMID 28115669 DOI: 10.4269/Ajtmh.16-0539 |
0.357 |
|
| 2016 |
Christensen SM, Dillon LA, Carvalho LP, Passos S, Novais FO, Hughitt VK, Beiting DP, Carvalho EM, Scott P, El-Sayed NM, Mosser DM. Meta-transcriptome Profiling of the Human-Leishmania braziliensis Cutaneous Lesion. Plos Neglected Tropical Diseases. 10: e0004992. PMID 27631090 DOI: 10.1371/Journal.Pntd.0004992 |
0.364 |
|
| 2016 |
Glennie ND, Scott P. Memory T cells in cutaneous leishmaniasis. Cellular Immunology. PMID 27493096 DOI: 10.1016/J.Cellimm.2016.07.010 |
0.392 |
|
| 2016 |
Weinkopff T, Konradt C, Christian DA, Discher DE, Hunter CA, Scott P. Leishmania major Infection-Induced VEGF-A/VEGFR-2 Signaling Promotes Lymphangiogenesis That Controls Disease. Journal of Immunology (Baltimore, Md. : 1950). PMID 27474074 DOI: 10.4049/Jimmunol.1600717 |
0.735 |
|
| 2016 |
Scott P, Novais FO. Cutaneous leishmaniasis: immune responses in protection and pathogenesis. Nature Reviews. Immunology. PMID 27424773 DOI: 10.1038/Nri.2016.72 |
0.451 |
|
| 2015 |
Crosby EJ, Clark M, Novais FO, Wherry EJ, Scott P. Lymphocytic Choriomeningitis Virus Expands a Population of NKG2D+CD8+ T Cells That Exacerbate Disease in Mice Coinfected with Leishmania major. Journal of Immunology (Baltimore, Md. : 1950). PMID 26290604 DOI: 10.4049/Jimmunol.1500855 |
0.49 |
|
| 2015 |
Gimblet C, Loesche MA, Carvalho L, Carvalho EM, Grice EA, Artis D, Scott P. IL-22 Protects against Tissue Damage during Cutaneous Leishmaniasis. Plos One. 10: e0134698. PMID 26285207 DOI: 10.1371/Journal.Pone.0134698 |
0.446 |
|
| 2015 |
Glennie ND, Yeramilli VA, Beiting DP, Volk SW, Weaver CT, Scott P. Skin-resident memory CD4+ T cells enhance protection against Leishmania major infection. The Journal of Experimental Medicine. 212: 1405-14. PMID 26216123 DOI: 10.1084/Jem.20142101 |
0.433 |
|
| 2015 |
Novais FO, Scott P. CD8+ T cells in cutaneous leishmaniasis: the good, the bad, and the ugly. Seminars in Immunopathology. 37: 251-9. PMID 25800274 DOI: 10.1007/S00281-015-0475-7 |
0.412 |
|
| 2015 |
Cardoso TM, Machado Ã, Costa DL, Carvalho LP, Queiroz A, Machado P, Scott P, Carvalho EM, Bacellar O. Protective and pathological functions of CD8+ T cells in Leishmania braziliensis infection. Infection and Immunity. 83: 898-906. PMID 25534940 DOI: 10.1128/Iai.02404-14 |
0.44 |
|
| 2015 |
Passos S, Carvalho LP, Costa RS, Campos TM, Novais FO, Magalhães A, Machado PR, Beiting D, Mosser D, Carvalho EM, Scott P. Intermediate monocytes contribute to pathologic immune response in Leishmania braziliensis infections. The Journal of Infectious Diseases. 211: 274-82. PMID 25139016 DOI: 10.1093/Infdis/Jiu439 |
0.398 |
|
| 2015 |
Novais FO, Carvalho LP, Passos S, Roos DS, Carvalho EM, Scott P, Beiting DP. Genomic profiling of human Leishmania braziliensis lesions identifies transcriptional modules associated with cutaneous immunopathology. The Journal of Investigative Dermatology. 135: 94-101. PMID 25036052 DOI: 10.1038/Jid.2014.305 |
0.335 |
|
| 2014 |
Crosby EJ, Goldschmidt MH, Wherry EJ, Scott P. Engagement of NKG2D on bystander memory CD8 T cells promotes increased immunopathology following Leishmania major infection. Plos Pathogens. 10: e1003970. PMID 24586170 DOI: 10.1371/Journal.Ppat.1003970 |
0.466 |
|
| 2014 |
Novais FO, Nguyen BT, Beiting DP, Carvalho LP, Glennie ND, Passos S, Carvalho EM, Scott P. Human classical monocytes control the intracellular stage of Leishmania braziliensis by reactive oxygen species. The Journal of Infectious Diseases. 209: 1288-96. PMID 24403561 DOI: 10.1093/Infdis/Jiu013 |
0.354 |
|
| 2013 |
Carvalho AM, Magalhães A, Carvalho LP, Bacellar O, Scott P, Carvalho EM. Immunologic response and memory T cells in subjects cured of tegumentary leishmaniasis. Bmc Infectious Diseases. 13: 529. PMID 24206576 DOI: 10.1186/1471-2334-13-529 |
0.437 |
|
| 2013 |
Novais FO, Carvalho LP, Graff JW, Beiting DP, Ruthel G, Roos DS, Betts MR, Goldschmidt MH, Wilson ME, de Oliveira CI, Scott P. Cytotoxic T cells mediate pathology and metastasis in cutaneous leishmaniasis. Plos Pathogens. 9: e1003504. PMID 23874205 DOI: 10.1371/Journal.Ppat.1003504 |
0.476 |
|
| 2013 |
Gonzalez-Lombana C, Gimblet C, Bacellar O, Oliveira WW, Passos S, Carvalho LP, Goldschmidt M, Carvalho EM, Scott P. IL-17 mediates immunopathology in the absence of IL-10 following Leishmania major infection. Plos Pathogens. 9: e1003243. PMID 23555256 DOI: 10.1371/Journal.Ppat.1003243 |
0.425 |
|
| 2013 |
Schamber-Reis BL, Petritus PM, Caetano BC, Martinez ER, Okuda K, Golenbock D, Scott P, Gazzinelli RT. UNC93B1 and nucleic acid-sensing Toll-like receptors mediate host resistance to infection with Leishmania major. The Journal of Biological Chemistry. 288: 7127-36. PMID 23325805 DOI: 10.1074/Jbc.M112.407684 |
0.385 |
|
| 2013 |
Petritus PM, Manzoni-de-Almeida D, Gimblet C, Lombana CG, Scott P. Fewer CD11b hi Ly6C + cells in the ear following L. mexicana infection compared to L. major . Plos Neglected Tropical Diseases. DOI: 10.1371/Journal.Pntd.0001858.G001 |
0.342 |
|
| 2013 |
Gimblet C, Artis D, Scott P. 94 Cytokine. 63: 265. DOI: 10.1016/J.Cyto.2013.06.097 |
0.468 |
|
| 2012 |
Petritus PM, Manzoni-de-Almeida D, Gimblet C, Gonzalez Lombana C, Scott P. Leishmania mexicana induces limited recruitment and activation of monocytes and monocyte-derived dendritic cells early during infection. Plos Neglected Tropical Diseases. 6: e1858. PMID 23094119 DOI: 10.1371/Journal.Pntd.0001858 |
0.465 |
|
| 2012 |
Passos S, Menezes T, Costa R, Mosser D, Scott P, Carvalho E, Carvalho L. P030 Subsets of circulating monocytes differently contribute to immunopathology in cutaneous leishmaniasis Cytokine. 59: 527-528. DOI: 10.1016/J.Cyto.2012.06.113 |
0.387 |
|
| 2011 |
Scott P. Leishmania - A parasitized parasite New England Journal of Medicine. 364: 1773-1774. PMID 21542750 DOI: 10.1056/Nejmcibr1101694 |
0.39 |
|
| 2010 |
Colpitts S, Scott P. Memory T-cell subsets in parasitic infections. Advances in Experimental Medicine and Biology. 684: 145-54. PMID 20795546 DOI: 10.1007/978-1-4419-6451-9_11 |
0.395 |
|
| 2010 |
Colpitts SL, Scott P. The early generation of a heterogeneous CD4+ T cell response to Leishmania major. Journal of Immunology (Baltimore, Md. : 1950). 185: 2416-23. PMID 20624946 DOI: 10.4049/jimmunol.1000483 |
0.333 |
|
| 2009 |
Liu J, Carvalho LP, Bhattacharya S, Carbone CJ, Kumar KG, Leu NA, Yau PM, Donald RG, Weiss MJ, Baker DP, McLaughlin KJ, Scott P, Fuchs SY. Mammalian casein kinase 1alpha and its leishmanial ortholog regulate stability of IFNAR1 and type I interferon signaling. Molecular and Cellular Biology. 29: 6401-12. PMID 19805514 DOI: 10.1128/Mcb.00478-09 |
0.332 |
|
| 2009 |
Scott P. Finding Leishmania: a deadly game of hide-and-seek. Cell Host & Microbe. 6: 3-4. PMID 19616760 DOI: 10.1016/J.Chom.2009.07.002 |
0.389 |
|
| 2009 |
Liu D, Kebaier C, Pakpour N, Capul AA, Beverley SM, Scott P, Uzonna JE. Leishmania major phosphoglycans influence the host early immune response by modulating dendritic cell functions. Infection and Immunity. 77: 3272-83. PMID 19487470 DOI: 10.1128/Iai.01447-08 |
0.514 |
|
| 2009 |
Bacellar O, Faria D, Nascimento M, Cardoso TM, Gollob KJ, Dutra WO, Scott P, Carvalho EM. Interleukin 17 production among patients with American cutaneous leishmaniasis. The Journal of Infectious Diseases. 200: 75-8. PMID 19476435 DOI: 10.1086/599380 |
0.402 |
|
| 2009 |
Colpitts SL, Dalton NM, Scott P. IL-7 receptor expression provides the potential for long-term survival of both CD62Lhigh central memory T cells and Th1 effector cells during Leishmania major infection. Journal of Immunology (Baltimore, Md. : 1950). 182: 5702-11. PMID 19380817 DOI: 10.4049/jimmunol.0803450 |
0.383 |
|
| 2008 |
Carvalho LP, Pearce EJ, Scott P. Functional dichotomy of dendritic cells following interaction with Leishmania braziliensis: infected cells produce high levels of TNF-alpha, whereas bystander dendritic cells are activated to promote T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 181: 6473-80. PMID 18941238 DOI: 10.4049/Jimmunol.181.9.6473 |
0.437 |
|
| 2008 |
Pakpour N, Zaph C, Scott P. The central memory CD4+ T cell population generated during Leishmania major infection requires IL-12 to produce IFN-gamma. Journal of Immunology (Baltimore, Md. : 1950). 180: 8299-305. PMID 18523296 DOI: 10.4049/Jimmunol.180.12.8299 |
0.463 |
|
| 2007 |
Hsu AC, Scott P. Leishmania mexicana infection induces impaired lymph node expansion and Th1 cell differentiation despite normal T cell proliferation Journal of Immunology. 179: 8200-8207. PMID 18056363 DOI: 10.4049/Jimmunol.179.12.8200 |
0.444 |
|
| 2007 |
Johnson LM, Scott P. STAT1 expression in dendritic cells, but not T cells, is required for immunity to Leishmania major. Journal of Immunology (Baltimore, Md. : 1950). 178: 7259-66. PMID 17513775 DOI: 10.4049/Jimmunol.178.11.7259 |
0.444 |
|
| 2007 |
Perrigoue JG, Li J, Zaph C, Goldschmidt M, Scott P, de Sauvage FJ, Pearce EJ, Ghilardi N, Artis D. IL-31-IL-31R interactions negatively regulate type 2 inflammation in the lung. The Journal of Experimental Medicine. 204: 481-7. PMID 17353366 DOI: 10.1084/Jem.20061791 |
0.428 |
|
| 2006 |
Gray PM, Reiner SL, Smith DF, Kaye PM, Scott P. Antigen-experienced T cells limit the priming of naive T cells during infection with Leishmania major. Journal of Immunology (Baltimore, Md. : 1950). 177: 925-33. PMID 16818747 DOI: 10.4049/Jimmunol.177.2.925 |
0.424 |
|
| 2006 |
Zaph C, Rook KA, Goldschmidt M, Mohrs M, Scott P, Artis D. Persistence and function of central and effector memory CD4+ T cells following infection with a gastrointestinal helminth. Journal of Immunology (Baltimore, Md. : 1950). 177: 511-8. PMID 16785548 DOI: 10.4049/Jimmunol.177.1.511 |
0.412 |
|
| 2006 |
Prickett S, Gray PM, Colpitts SL, Scott P, Kaye PM, Smith DF. In vivo recognition of ovalbumin expressed by transgenic Leishmania is determined by its subcellular localization. Journal of Immunology (Baltimore, Md. : 1950). 176: 4826-33. PMID 16585577 DOI: 10.4049/Jimmunol.176.8.4826 |
0.387 |
|
| 2006 |
Kébaïer C, Uzonna JE, Beverley SM, Scott P. Immunization with persistent attenuated Delta lpg2 Leishmania major parasites requires adjuvant to provide protective immunity in C57BL/6 mice. Infection and Immunity. 74: 777-80. PMID 16369039 DOI: 10.1128/Iai.74.1.777-780.2006 |
0.388 |
|
| 2006 |
Sweeney RW, Uzonna J, Whitlock RH, Habecker PL, Chilton P, Scott P. Tissue predilection sites and effect of dose on Mycobacterium avium subs. paratuberculosis organism recovery in a short-term bovine experimental oral infection model Research in Veterinary Science. 80: 253-259. PMID 16165171 DOI: 10.1016/J.Rvsc.2005.07.007 |
0.319 |
|
| 2005 |
Scott P. Immunologic memory in cutaneous leishmaniasis. Cellular Microbiology. 7: 1707-1713. PMID 16309457 DOI: 10.1111/J.1462-5822.2005.00626.X |
0.423 |
|
| 2005 |
Hutchins AS, Artis D, Hendrich BD, Bird AP, Scott P, Reiner SL. Cutting edge: a critical role for gene silencing in preventing excessive type 1 immunity. Journal of Immunology (Baltimore, Md. : 1950). 175: 5606-10. PMID 16237047 DOI: 10.4049/Jimmunol.175.9.5606 |
0.443 |
|
| 2005 |
Oliveira MR, Tafuri WL, Afonso LC, Oliveira MA, Nicoli JR, Vieira EC, Scott P, Melo MN, Vieira LQ. Germ-free mice produce high levels of interferon-gamma in response to infection with Leishmania major but fail to heal lesions. Parasitology. 131: 477-88. PMID 16174412 DOI: 10.1017/S0031182005008073 |
0.484 |
|
| 2005 |
Artis D, Kane CM, Fiore J, Zaph C, Shapira S, Joyce K, Macdonald A, Hunter C, Scott P, Pearce EJ. Dendritic cell-intrinsic expression of NF-kappa B1 is required to promote optimal Th2 cell differentiation. Journal of Immunology (Baltimore, Md. : 1950). 174: 7154-9. PMID 15905559 DOI: 10.4049/Jimmunol.174.11.7154 |
0.43 |
|
| 2005 |
Buxbaum LU, Scott P. Interleukin 10- and Fcγ Receptor-Deficient Mice Resolve Leishmania mexicana Lesions Infection and Immunity. 73: 2101-2108. PMID 15784551 DOI: 10.1128/Iai.73.4.2101-2108.2005 |
0.454 |
|
| 2005 |
Hunter CA, Villarino A, Artis D, Scott P. The role of IL-27 in the development of T-cell responses during parasitic infections. Immunological Reviews. 202: 106-14. PMID 15546389 DOI: 10.1111/J.0105-2896.2004.00213.X |
0.459 |
|
| 2005 |
Scott P, Artis D, Uzonna J, Zaph C. The development of effector and memory T cells in cutaneous leishmaniasis: the implications for vaccine development. Immunological Reviews. 201: 318-38. PMID 15361250 DOI: 10.1111/J.0105-2896.2004.00198.X |
0.447 |
|
| 2004 |
Artis D, Villarino A, Silverman M, He W, Thornton EM, Mu S, Summer S, Covey TM, Huang E, Yoshida H, Koretzky G, Goldschmidt M, Wu GD, de Sauvage F, Miller HR, ... ... Scott P, et al. The IL-27 receptor (WSX-1) is an inhibitor of innate and adaptive elements of type 2 immunity. Journal of Immunology (Baltimore, Md. : 1950). 173: 5626-34. PMID 15494513 DOI: 10.4049/Jimmunol.173.9.5626 |
0.459 |
|
| 2004 |
Zaph C, Uzonna J, Beverley SM, Scott P. Central memory T cells mediate long-term immunity to Leishmania major in the absence of persistent parasites. Nature Medicine. 10: 1104-10. PMID 15448686 DOI: 10.1038/Nm1108 |
0.306 |
|
| 2004 |
Robinson TM, Nelson R, Artis D, Scott P, Boyer JD. Experimental Leishmania major infection suppresses HIV-1 DNA vaccine induced cellular immune response. Cells, Tissues, Organs. 177: 185-8. PMID 15388992 DOI: 10.1159/000079992 |
0.401 |
|
| 2004 |
Dalton JE, Howell G, Pearson J, Scott P, Carding SR. Fas-Fas ligand interactions are essential for the binding to and killing of activated macrophages by gamma delta T cells. Journal of Immunology (Baltimore, Md. : 1950). 173: 3660-7. PMID 15356111 DOI: 10.4049/Jimmunol.173.6.3660 |
0.409 |
|
| 2004 |
Artis D, Wang ML, Keilbaugh SA, He W, Brenes M, Swain GP, Knight PA, Donaldson DD, Lazar MA, Miller HR, Schad GA, Scott P, Wu GD. RELMbeta/FIZZ2 is a goblet cell-specific immune-effector molecule in the gastrointestinal tract. Proceedings of the National Academy of Sciences of the United States of America. 101: 13596-600. PMID 15340149 DOI: 10.1073/Pnas.0404034101 |
0.518 |
|
| 2004 |
Uzonna JE, Joyce KL, Scott P. Low dose Leishmania major promotes a transient T helper cell type 2 response that is down-regulated by interferon γ-producing CD8+ T cells Journal of Experimental Medicine. 199: 1559-1566. PMID 15184505 DOI: 10.1084/Jem.20040172 |
0.452 |
|
| 2004 |
Artis D, Johnson LM, Joyce K, Saris C, Villarino A, Hunter CA, Scott P. Cutting edge: early IL-4 production governs the requirement for IL-27-WSX-1 signaling in the development of protective Th1 cytokine responses following Leishmania major infection. Journal of Immunology (Baltimore, Md. : 1950). 172: 4672-5. PMID 15067040 DOI: 10.4049/Jimmunol.172.8.4672 |
0.444 |
|
| 2004 |
Uzonna JE, Späth GF, Beverley SM, Scott P. Vaccination with phosphoglycan-deficient Leishmania major protects highly susceptible mice from virulent challenge without inducing a strong Th1 response. Journal of Immunology (Baltimore, Md. : 1950). 172: 3793-7. PMID 15004184 DOI: 10.4049/Jimmunol.172.6.3793 |
0.486 |
|
| 2004 |
Lemos MP, Esquivel F, Scott P, Laufer TM. MHC class II expression restricted to CD8alpha+ and CD11b+ dendritic cells is sufficient for control of Leishmania major. The Journal of Experimental Medicine. 199: 725-30. PMID 14993255 DOI: 10.1084/Jem.20030795 |
0.451 |
|
| 2004 |
Speirs K, Lieberman L, Caamano J, Hunter CA, Scott P. Cutting Edge: NF-κB2 Is a Negative Regulator of Dendritic Cell Function Journal of Immunology. 172: 752-756. PMID 14707043 DOI: 10.4049/Jimmunol.172.2.752 |
0.337 |
|
| 2003 |
Dalton JE, Pearson J, Scott P, Carding SR. The interaction of gamma delta T cells with activated macrophages is a property of the V gamma 1 subset. Journal of Immunology (Baltimore, Md. : 1950). 171: 6488-94. PMID 14662848 DOI: 10.4049/Jimmunol.171.12.6488 |
0.399 |
|
| 2003 |
Zaph C, Scott P. Th1 Cell-Mediated Resistance to Cutaneous Infection with Leishmania major Is Independent of P- and E-Selectins Journal of Immunology. 171: 4726-4732. PMID 14568948 DOI: 10.4049/Jimmunol.171.9.4726 |
0.472 |
|
| 2003 |
Buxbaum LU, Denise H, Coombs GH, Alexander J, Mottram JC, Scott P. Cysteine protease B of Leishmania mexicana inhibits host Th1 responses and protective immunity. Journal of Immunology (Baltimore, Md. : 1950). 171: 3711-7. PMID 14500670 DOI: 10.4049/Jimmunol.171.7.3711 |
0.456 |
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| 2003 |
Kobayashi T, Walsh PT, Walsh MC, Speirs KM, Chiffoleau E, King CG, Hancock WW, Caamano JH, Hunter CA, Scott P, Turka LA, Choi Y. TRAF6 is a critical factor for dendritic cell maturation and development. Immunity. 19: 353-63. PMID 14499111 DOI: 10.1016/S1074-7613(03)00230-9 |
0.399 |
|
| 2003 |
Scott P. Development and regulation of cell-mediated immunity in experimental leishmaniasis. Immunologic Research. 27: 489-498. PMID 12857992 DOI: 10.1385/Ir:27:2-3:489 |
0.491 |
|
| 2003 |
Zaph C, Scott P. Interleukin-12 regulates chemokine gene expression during the early immune response to Leishmania major. Infection and Immunity. 71: 1587-1589. PMID 12595483 DOI: 10.1128/Iai.71.3.1587-1589.2003 |
0.42 |
|
| 2003 |
Artis D, Speirs K, Joyce K, Goldschmidt M, Caamaño J, Hunter CA, Scott P. NF-kappa B1 is required for optimal CD4+ Th1 cell development and resistance to Leishmania major. Journal of Immunology (Baltimore, Md. : 1950). 170: 1995-2003. PMID 12574369 DOI: 10.4049/Jimmunol.170.4.1995 |
0.517 |
|
| 2003 |
Pollock KG, McNeil KS, Mottram JC, Lyons RE, Brewer JM, Scott P, Coombs GH, Alexander J. The Leishmania mexicana cysteine protease, CPB2.8, induces potent Th2 responses. Journal of Immunology (Baltimore, Md. : 1950). 170: 1746-53. PMID 12574338 DOI: 10.4049/Jimmunol.170.4.1746 |
0.467 |
|
| 2002 |
Buxbaum LU, Uzonna JE, Goldschmidt MH, Scott P. Control of New World cutaneous leishmaniasis is IL-12 independent but STAT4 dependent European Journal of Immunology. 32: 3206-3215. PMID 12555666 DOI: 10.1002/1521-4141(200211)32:11<3206::Aid-Immu3206>3.0.Co;2-J |
0.47 |
|
| 2002 |
Krolewiecki A, Leon S, Scott P, Abraham D. Activity of azithromycin against Leishmania major in vitro and in vivo. American Journal of Tropical Medicine and Hygiene. 67: 273-277. PMID 12408666 DOI: 10.4269/Ajtmh.2002.67.273 |
0.441 |
|
| 2002 |
Artis D, Shapira S, Mason N, Speirs KM, Goldschmidt M, Caamaño J, Liou HC, Hunter CA, Scott P. Differential requirement for NF-kappa B family members in control of helminth infection and intestinal inflammation. Journal of Immunology (Baltimore, Md. : 1950). 169: 4481-7. PMID 12370384 DOI: 10.4049/Jimmunol.169.8.4481 |
0.444 |
|
| 2002 |
Li J, Padigel UM, Scott P, Farrell JP. Combined treatment with interleukin-12 and indomethacin promotes increased resistance in BALB/c mice with established Leishmania major infections. Infection and Immunity. 70: 5715-20. PMID 12228301 DOI: 10.1128/Iai.70.10.5715-5720.2002 |
0.469 |
|
| 2002 |
La Flamme AC, Scott P, Pearce EJ. Schistosomiasis delays lesion resolution during Leishmania major infection by impairing parasite killing by macrophages. Parasite Immunology. 24: 339-45. PMID 12164819 DOI: 10.1046/J.1365-3024.2002.00473.X |
0.508 |
|
| 2002 |
Scott P, Hunter CA. Dendritic cells and immunity to leishmaniasis and toxoplasmosis Current Opinion in Immunology. 14: 466-470. PMID 12088681 DOI: 10.1016/S0952-7915(02)00353-9 |
0.393 |
|
| 2002 |
Park AY, Hondowicz B, Kopf M, Scott P. The role of IL-12 in maintaining resistance to Leishmania major. Journal of Immunology (Baltimore, Md. : 1950). 168: 5771-7. PMID 12023378 DOI: 10.4049/Jimmunol.168.11.5771 |
0.455 |
|
| 2002 |
Speirs K, Caamano J, Goldschmidt MH, Hunter CA, Scott P. NF-κB2 Is Required for Optimal CD40-Induced IL-12 Production but Dispensable for Th1 Cell Differentiation Journal of Immunology. 168: 4406-4413. PMID 11970983 DOI: 10.4049/Jimmunol.168.9.4406 |
0.424 |
|
| 2002 |
Jones DE, Ackermann MR, Wille U, Hunter CA, Scott P. Early enhanced Th1 response after Leishmania amazonensis infection of C57BL/6 interleukin-10-deficient mice does not lead to resolution of infection. Infection and Immunity. 70: 2151-8. PMID 11895981 DOI: 10.1128/Iai.70.4.2151-2158.2002 |
0.502 |
|
| 2002 |
Hondowicz B, Scott P. Influence of parasite load on the ability of type 1 T cells to control Leishmania major infection. Infection and Immunity. 70: 498-503. PMID 11796575 DOI: 10.1128/Iai.70.2.498-503.2002 |
0.471 |
|
| 2001 |
Riley MP, Shih FF, Jordan MS, Petrone AL, Cerasoli DM, Scott P, Caton AJ. CD4+ T cells that evade deletion by a self peptide display Th1-biased differentiation. European Journal of Immunology. 31: 311-9. PMID 11265648 DOI: 10.1002/1521-4141(200101)31:1<311::Aid-Immu311>3.0.Co;2-G |
0.377 |
|
| 2001 |
Elloso MM, Scott P. Differential requirement of CD28 for IL‐12 receptor expression and function in CD4+ and CD8+ T cells European Journal of Immunology. 31: 384-395. PMID 11180102 DOI: 10.1002/1521-4141(200102)31:2<384::Aid-Immu384>3.0.Co;2-9 |
0.381 |
|
| 2001 |
Constantinescu CS, Hilliard B, Ventura E, Wysocka M, Showe L, Lavi E, Fujioka T, Scott P, Trinchieri G, Rostami A. Modulation of susceptibility and resistance to an autoimmune model of multiple sclerosis in prototypically susceptible and resistant strains by neutralization of interleukin-12 and interleukin-4, respectively. Clinical Immunology (Orlando, Fla.). 98: 23-30. PMID 11141323 DOI: 10.1006/Clim.2000.4944 |
0.4 |
|
| 2001 |
Gicheru MM, Olobo JO, Anjili CO, Orago AS, Modabber F, Scott P. Vervet Monkeys Vaccinated with Killed Leishmania major Parasites and Interleukin-12 Develop a Type 1 Immune Response but Are Not Protected against Challenge Infection Infection and Immunity. 69: 245-251. PMID 11119512 DOI: 10.1128/Iai.69.1.245-251.2001 |
0.475 |
|
| 2000 |
Hondowicz BD, Park AY, Elloso MM, Scott P. Maintenance of IL-12-responsive CD4+ T cells during a Th2 response in Leishmania major-infected mice. European Journal of Immunology. 30: 2007-14. PMID 10940890 DOI: 10.1002/1521-4141(200007)30:7<2007::Aid-Immu2007>3.0.Co;2-W |
0.446 |
|
| 2000 |
Park AY, Hondowicz BD, Scott P. IL-12 is required to maintain a Th1 response during Leishmania major infection. Journal of Immunology (Baltimore, Md. : 1950). 165: 896-902. PMID 10878364 DOI: 10.4049/Jimmunol.165.2.896 |
0.476 |
|
| 2000 |
Jones DE, Buxbaum LU, Scott P. IL-4-Independent Inhibition of IL-12 Responsiveness During Leishmania amazonensis Infection Journal of Immunology. 165: 364-372. PMID 10861073 DOI: 10.4049/Jimmunol.165.1.364 |
0.453 |
|
| 2000 |
Lee JY, Atochina O, King B, Taylor L, Elloso M, Scott P, Rossman MD. Beryllium, an adjuvant that promotes gamma interferon production. Infection and Immunity. 68: 4032-9. PMID 10858219 DOI: 10.1128/Iai.68.7.4032-4039.2000 |
0.445 |
|
| 2000 |
Nashleanas M, Scott P. Activated T Cells Induce Macrophages To Produce NO and Control Leishmania major in the Absence of Tumor Necrosis Factor Receptor p55 Infection and Immunity. 68: 1428-1434. PMID 10678956 DOI: 10.1128/Iai.68.3.1428-1434.2000 |
0.421 |
|
| 1999 |
Hondowicz B, Scott P. Influence of host and parasite factors on the innate immune response and Th2 stability following infection with Leishmania major. Microbes and Infection. 1: 65-71. PMID 10847768 DOI: 10.1016/S1286-4579(99)80016-1 |
0.407 |
|
| 1999 |
Fernandez-Botran R, Chilton PM, Hondowicz BD, Vetvickova J, Yan J, Jones W, Scott P. Regulation of the production of soluble IL-4 receptors in murine cutaneous leishmaniasis. The roles of IL-12 and IL-4. Journal of Leukocyte Biology. 66: 481-488. PMID 10496319 DOI: 10.1002/Jlb.66.3.481 |
0.422 |
|
| 1998 |
Constantinescu CS, Hondowicz BD, Elloso MM, Wysocka M, Trinchieri G, Scott P. The role of IL-12 in the maintenance of an established Th1 immune response in experimental leishmaniasis. European Journal of Immunology. 28: 2227-2233. PMID 9692892 DOI: 10.1002/(Sici)1521-4141(199807)28:07<2227::Aid-Immu2227>3.0.Co;2-N |
0.504 |
|
| 1998 |
Jones D, Elloso MM, Showe L, Williams D, Trinchieri G, Scott P. Differential Regulation of the Interleukin-12 Receptor during the Innate Immune Response to Leishmania major Infection and Immunity. 66: 3818-3824. PMID 9673267 DOI: 10.1128/Iai.66.8.3818-3824.1998 |
0.447 |
|
| 1998 |
Scott P, Farrell JP. Experimental cutaneous leishmaniasis: induction and regulation of T cells following infection of mice with Leishmania major. Chemical Immunology. 70: 60-80. PMID 9509670 DOI: 10.1159/000058698 |
0.448 |
|
| 1998 |
Scott P. Differentiation, regulation, and death of T helper cell subsets during infection with Leishmania major Immunologic Research. 17: 229-238. PMID 9479584 DOI: 10.1007/Bf02786447 |
0.522 |
|
| 1997 |
Scott P, Trinchieri G. IL-12 as an adjuvant for cell-mediated immunity. Seminars in Immunology. 9: 285-291. PMID 9327523 DOI: 10.1006/Smim.1997.0084 |
0.397 |
|
| 1997 |
Rotman HL, Schnyder-Candrian S, Scott P, Nolan TJ, Schad GA, Abraham D. IL-12 eliminates the Th-2 dependent protective immune response of mice to larval Strongyloides stercoralis. Parasite Immunology. 19: 29-39. PMID 9121838 DOI: 10.1046/J.1365-3024.1997.D01-142.X |
0.466 |
|
| 1996 |
Scott P, Hondowicz B, Eaton A, Scharton-Kersten T. The role of IL-12 in regulation of T helper cell subsets in vivo. Lessons from experimental cutaneous leishmaniasis. Annals of the New York Academy of Sciences. 795: 250-6. PMID 8958936 DOI: 10.1111/J.1749-6632.1996.Tb52674.X |
0.406 |
|
| 1996 |
Li J, Scott P, Farrell JP. In vivo alterations in cytokine production following interleukin-12 (IL-12) and anti-IL-4 antibody treatment of CB6F1 mice with chronic cutaneous leishmaniasis. Infection and Immunity. 64: 5248-54. PMID 8945573 DOI: 10.1128/Iai.64.12.5248-5254.1996 |
0.465 |
|
| 1996 |
Scott P, Eaton A, Gause WC, di Zhou X, Hondowicz B. Early IL-4 production does not predict susceptibility to Leishmania major. Experimental Parasitology. 84: 178-87. PMID 8932767 DOI: 10.1006/Expr.1996.0103 |
0.43 |
|
| 1996 |
Scott P. Th cell development and regulation in experimental cutaneous leishmaniasis. Chemical Immunology. 63: 98-114. DOI: 10.1159/000319481 |
0.334 |
|
| 1995 |
Scott P, Trinchieri G. The role of natural killer cells in host—parasite interactions Current Opinion in Immunology. 7: 34-40. PMID 7772279 DOI: 10.1016/0952-7915(95)80026-3 |
0.369 |
|
| 1995 |
Nabors GS, Afonso LC, Farrell JP, Scott P. Switch from a type 2 to a type 1 T helper cell response and cure of established Leishmania major infection in mice is induced by combined therapy with interleukin 12 and Pentostam. Proceedings of the National Academy of Sciences of the United States of America. 92: 3142-6. PMID 7724530 DOI: 10.1073/Pnas.92.8.3142 |
0.476 |
|
| 1995 |
Scharton-Kersten T, Scott P. The role of the innate immune response in Th1 cell development following Leishmania major infection. Journal of Leukocyte Biology. 57: 515-522. PMID 7722408 DOI: 10.1002/Jlb.57.4.515 |
0.498 |
|
| 1995 |
Wysocka M, Kubin M, Vieira LQ, Ozmen L, Garotta G, Scott P, Trinchieri G. Interleukin-12 Is Required For Interferon-Gamma Production And Lethality In Lipopolysaccharide-Induced Shock In Mice European Journal of Immunology. 25: 672-676. PMID 7705395 DOI: 10.1002/Eji.1830250307 |
0.378 |
|
| 1994 |
Scott P, Scharton T. Interaction between the Innate and the Acquired Immune System following Infection of Different Mouse Strains with Leishmania majora Annals of the New York Academy of Sciences. 730: 84-92. PMID 8080217 DOI: 10.1111/J.1749-6632.1994.Tb44241.X |
0.362 |
|
| 1994 |
Trinchieri G, Scott P. The role of interleukin 12 in the immune response, disease and therapy Immunology Today. 15: 460-463. PMID 7945769 DOI: 10.1016/0167-5699(94)90189-9 |
0.444 |
|
| 1994 |
Vieira LQ, Hondowicz BD, Afonso LCC, Wysocka M, Trinchieri G, Scott P. Infection with Leishmania major induces interleukin-12 production in vivo. Immunology Letters. 40: 157-161. PMID 7916331 DOI: 10.1016/0165-2478(94)90187-2 |
0.486 |
|
| 1994 |
Afonso LCC, Scharton TM, Vieira LQ, Wysocka M, Trinchieri G, Scott P. The adjuvant effect of interleukin-12 in a vaccine against Leishmania major Science. 263: 235-237. PMID 7904381 DOI: 10.1126/Science.7904381 |
0.415 |
|
| 1993 |
Afonso LCC, Scott P. Immune responses associated with susceptibility of C57BL/10 mice to Leishmania amazonensis. Infection and Immunity. 61: 2952-2959. PMID 8514400 DOI: 10.1128/Iai.61.7.2952-2959.1993 |
0.509 |
|
| 1993 |
Reiner SL, Wang ZE, Hatam F, Scott P, Locksley RM. TH1 and TH2 cell antigen receptors in experimental leishmaniasis Science. 259: 1457-1463. PMID 8451641 DOI: 10.1126/Science.8451641 |
0.454 |
|
| 1993 |
Scott P. Selective differentiation of CD4+ T helper cell subsets Current Opinion in Immunology. 5: 391-397. PMID 8102235 DOI: 10.1016/0952-7915(93)90058-Z |
0.38 |
|
| 1993 |
Scharton TM, Scott P. Natural killer cells are a source of interferon gamma that drives differentiation of CD4+ T cell subsets and induces early resistance to Leishmania major in mice. Journal of Experimental Medicine. 178: 567-577. PMID 8101861 DOI: 10.1084/Jem.178.2.567 |
0.478 |
|
| 1993 |
Scott P. IL-12: Initiation cytokine for cell-mediated immunity Science. 260: 496-497. PMID 8097337 DOI: 10.1126/Science.8097337 |
0.408 |
|
| 1991 |
Coffman RL, Varkila K, Scott P, Chatelain R. Role of cytokines in the differentiation of CD4+ T-cell subsets in vivo. Immunological Reviews. 123: 189-207. PMID 1684779 DOI: 10.1111/J.1600-065X.1991.Tb00611.X |
0.367 |
|
| 1991 |
Scott P, Kaufmann SHE. The role of T-cell subsets and cytokines in the regulation of infection Immunology Today. 12: 346-348. PMID 1683536 DOI: 10.1016/0167-5699(91)90063-Y |
0.425 |
|
| 1990 |
Scott P, Pearce E, Cheever AW, Coffman RL, Sher A. Role of cytokines and CD4+ T-cell subsets in the regulation of parasite immunity and disease. Immunological Reviews. 112: 161-82. PMID 2575073 DOI: 10.1111/J.1600-065X.1989.Tb00557.X |
0.508 |
|
| 1989 |
Scott P, Natovitz P, Coffman RL, Pearce E, Sher A. CD4+ T cell subsets in experimental cutaneous leishmaniasis. Memorias Do Instituto Oswaldo Cruz. 256-9. PMID 3267029 DOI: 10.1590/S0074-02761988000500006 |
0.334 |
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