Ilme Schlichting - Publications

Affiliations: 
Biomolecular Mechanisms Max Planck Institute for Medical Research, Heidelberg, Baden-Württemberg, Germany 

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Erk B, Rolles D, Foucar L, Rudek B, Epp SW, Cryle M, Bostedt C, Schorb S, Bozek J, Rouzee A, Hundertmark A, Marchenko T, Simon M, Filsinger F, Christensen L, ... ... Schlichting I, et al. Ultrafast Charge Rearrangement and Nuclear Dynamics upon Inner-Shell Multiple Ionization of Small Polyatomic Molecules Physical Review Letters. 110. DOI: 10.1103/PhysRevLett.110.053003  0.515
2013 Erk B, Rolles D, Foucar L, Rudek B, Epp SW, Cryle M, Bostedt C, Schorb S, Bozek J, Rouzee A, Hundertmark A, Marchenko T, Simon M, Filsinger F, Christensen L, ... ... Schlichting I, et al. Inner-shell multiple ionization of polyatomic molecules with an intense x-ray free-electron laser studied by coincident ion momentum imaging Journal of Physics B: Atomic, Molecular and Optical Physics. 46. DOI: 10.1088/0953-4075/46/16/164031  0.548
2012 Kassemeyer S, Steinbrener J, Lomb L, Hartmann E, Aquila A, Barty A, Martin AV, Hampton CY, Bajt S, Barthelmess M, Barends TR, Bostedt C, Bott M, Bozek JD, Coppola N, ... ... Schlichting I, et al. Femtosecond free-electron laser x-ray diffraction data sets for algorithm development. Optics Express. 20: 4149-58. PMID 22418172 DOI: 10.1364/Oe.20.004149  0.54
2012 Erk B, Rudenko A, Rolles D, Rudek B, Foucar L, Epp S, Cryle M, Schlichting I, Bostedt C, Schorb S, Bozek J, Rouzee A, Hundertmark A, Marchenko T, Simon M, et al. Coulomb explosion imaging of small organic molecules at LCLS Journal of Physics: Conference Series. 388. DOI: 10.1088/1742-6596/388/2/022108  0.501
2011 Cryle MJ, Staaden J, Schlichting I. Structural characterization of CYP165D3, a cytochrome P450 involved in phenolic coupling in teicoplanin biosynthesis. Archives of Biochemistry and Biophysics. 507: 163-73. PMID 20974107 DOI: 10.1016/j.abb.2010.10.017  0.595
2010 Cryle MJ, Bell SG, Schlichting I. Structural and biochemical characterization of the cytochrome P450 CypX (CYP134A1) from Bacillus subtilis: a cyclo-L-leucyl-L-leucyl dipeptide oxidase. Biochemistry. 49: 7282-96. PMID 20690619 DOI: 10.1021/Bi100910Y  0.581
2010 Cryle MJ, Meinhart A, Schlichting I. Structural characterization of OxyD, a cytochrome P450 involved in beta-hydroxytyrosine formation in vancomycin biosynthesis. The Journal of Biological Chemistry. 285: 24562-74. PMID 20519494 DOI: 10.1074/jbc.M110.131904  0.617
2009 Glas AF, Maul MJ, Cryle M, Barends TRM, Schneider S, Kaya E, Schlichting I, Carell T. The archaeal cofactor F0 is a light-harvesting antenna chromophore in eukaryotes Proceedings of the National Academy of Sciences of the United States of America. 106: 11540-11545. PMID 19570997 DOI: 10.1073/Pnas.0812665106  0.541
2009 Novak WR, Moulin AG, Blakeley MP, Schlichting I, Petsko GA, Ringe D. A preliminary neutron diffraction study of gamma-chymotrypsin. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 65: 317-20. PMID 19255494 DOI: 10.1107/S1744309109006630  0.701
2009 Barends T, Domratcheva T, Maul M, Cryle M, Glas A, Schneider S, Carell T, Schlichting I. Light-driven repair of DNA damage by Drosophila (6-4)-photolyase Acta Crystallographica Section A. 65: 17-17. DOI: 10.1107/S0108767309099711  0.498
2008 Maul MJ, Barends TRM, Glas AF, Cryle MJ, Domratcheva T, Schneider S, Schlichting I, Carell T. Crystal structure and mechanism of a DNA (6-4) photolyase Angewandte Chemie - International Edition. 47: 10076-10080. PMID 18956392 DOI: 10.1002/Anie.200804268  0.577
2008 Cryle MJ, Schlichting I. Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450(BioI) ACP complex. Proceedings of the National Academy of Sciences of the United States of America. 105: 15696-701. PMID 18838690 DOI: 10.1073/pnas.0805983105  0.603
2008 Kühnel K, Ke N, Cryle MJ, Sligar SG, Schuler MA, Schlichting I. Crystal structures of substrate-free and retinoic acid-bound cyanobacterial cytochrome P450 CYP120A1. Biochemistry. 47: 6552-9. PMID 18512957 DOI: 10.1021/Bi800328S  0.606
2006 Blankenfeldt W, Thomä NH, Wray JS, Gautel M, Schlichting I. Crystal structures of human cardiac beta-myosin II S2-Delta provide insight into the functional role of the S2 subfragment. Proceedings of the National Academy of Sciences of the United States of America. 103: 17713-7. PMID 17095604 DOI: 10.1073/pnas.0606741103  0.667
2005 Scheffzek K, Kabsch W, Schlichting I, Pai EF, Lautwein A, Frech M, Wittinghoffer A, Goody RS. Crystallization and preliminary X-ray structure analysis of thermally unstable p21(H-ras) guanosine complexes. Acta Crystallographica. Section D, Biological Crystallography. 50: 521-6. PMID 15299413 DOI: 10.1107/S0907444994001253  0.334
2003 Pylypenko O, Rak A, Reents R, Niculae A, Sidorovitch V, Cioaca MD, Bessolitsyna E, Thomä NH, Waldmann H, Schlichting I, Goody RS, Alexandrov K. Structure of Rab escort protein-1 in complex with Rab geranylgeranyltransferase. Molecular Cell. 11: 483-94. PMID 12620235 DOI: 10.1016/S1097-2765(03)00044-3  0.586
2000 Ostermann N, Lavie A, Padiyar S, Brundiers R, Veit T, Reinstein J, Goody RS, Konrad M, Schlichting I. Potentiating AZT activation: Structures of wild-type and mutant human thymidylate kinase suggest reasons for the mutants' improved kinetics with the HIV prodrug metabolite AZTMP Journal of Molecular Biology. 304: 43-53. PMID 11071809 DOI: 10.1006/Jmbi.2000.4175  0.552
2000 Ostermann N, Schlichting I, Brundiers R, Konrad M, Reinstein J, Veit T, Goody RS, Lavie A. Insights into the phosphoryltransfer mechanism of human thymidylate kinase gained from crystal structures of enzyme complexes along the reaction coordinate Structure. 8: 629-642. PMID 10873853 DOI: 10.1016/S0969-2126(00)00149-0  0.579
2000 Schlichting I, Berendzen J, Chu K, Stock AM, Maves SA, Benson DE, Sweet RM, Ringe D, Petsko GA, Sligar SG. The catalytic pathway of cytochrome p450cam at atomic resolution. Science (New York, N.Y.). 287: 1615-22. PMID 10698731 DOI: 10.1126/Science.287.5458.1615  0.655
1999 Brundiers R, Lavie A, Veit T, Reinstein J, Schlichting I, Ostermann N, Goody RS, Konrad M. Modifying human thymidylate kinase to potentiate azidothymidine activation Journal of Biological Chemistry. 274: 35289-35292. PMID 10585390 DOI: 10.1074/Jbc.274.50.35289  0.509
1998 Lavie A, Ostermann N, Brundiers R, Goody RS, Reinstein J, Konrad M, Schlichting I. Structural basis for efficient phosphorylation of 3'-azidothymidine monophosphate by Escherichia coli thymidylate kinase Proceedings of the National Academy of Sciences of the United States of America. 95: 14045-14050. PMID 9826650 DOI: 10.1073/Pnas.95.24.14045  0.567
1998 Hasson MS, Schlichting I, Moulai J, Taylor K, Barrett W, Kenyon GL, Babbitt PC, Gerlt JA, Petsko GA, Ringe D. Evolution of an enzyme active site: the structure of a new crystal form of muconate lactonizing enzyme compared with mandelate racemase and enolase. Proceedings of the National Academy of Sciences of the United States of America. 95: 10396-401. PMID 9724714 DOI: 10.1073/Pnas.95.18.10396  0.492
1998 Lavie A, Konrad M, Brundiers R, Goody RS, Schlichting I, Reinstein J. Crystal structure of yeast thymidylate kinase complexed with the bisubstrate inhibitor P1-(5'-adenosyl) P5-(5'-thymidyl) pentaphosphate (TP5A) at 2.0 Å resolution: Implications for catalysis and AZT activation Biochemistry. 37: 3677-3686. PMID 9521686 DOI: 10.1021/Bi9720787  0.587
1998 Balzarini J, Degreve B, De Clercq E, Lavie A, Reinstein J, Goody RS, Schlichting I. Improving AZT efficacy Nature Medicine. 4: 132. PMID 9461164 DOI: 10.1038/Nm0298-132A  0.417
1998 Lavie A, Reinstein J, Goody RS, Schlichting I, Konrad M. Reply to “Improving AZT efficacy” Nature Medicine. 4: 132-132. DOI: 10.1038/Nm0298-132B  0.41
1997 Hasson MS, Schlichting I, McGowen MM, Woolridge EM, Kozarich JW, Petsko GA, Ringe D. Characterization of two crystal forms of 3-carboxy-cis,cis-muconate lactonizing enzyme from Pseudomonas putida. Acta Crystallographica. Section D, Biological Crystallography. 53: 352-3. PMID 15299946 DOI: 10.1107/S0907444996015648  0.414
1997 Lavie A, Schlichting I, Vetter IR, Konrad M, Reinstein J, Goody RS. The bottleneck in AZT activation Nature Medicine. 3: 922-924. PMID 9256287 DOI: 10.1038/Nm0897-922  0.496
1997 Lavie A, Vetter IR, Konrad M, Goody RS, Reinstein J, Schlichting I. Structure of thymidylate kinase reveals the cause behind the limiting step in AZT activation Nature Structural Biology. 4: 601-604. PMID 9253404 DOI: 10.1038/Nsb0897-601  0.526
1996 Schlichting I, Berendzen J, Chu K, Stock AM, Davies M, Mueller EJ, Sligar S, Sweet RM, Ringe D, Petsko GA. Intermediates in the reaction pathway of cytochrome P450cam Acta Crystallographica Section a Foundations of Crystallography. 52: C49-C49. DOI: 10.1107/S0108767396097085  0.581
1996 Lavie A, Vetter I, Konrad M, Goody R, Reinstein J, Schlichting I. Crystal structure of thymidylate kinase fromSaccharomyces cerevisiaewith substrate bound Acta Crystallographica Section a Foundations of Crystallography. 52: C169-C169. DOI: 10.1107/S0108767396092525  0.551
1994 Xie X, Harrison DH, Schlichting I, Sweet RM, Kalabokis VN, Szent-Györgyi AG, Cohen C. Structure of the regulatory domain of scallop myosin at 2.8 A resolution. Nature. 368: 306-12. PMID 8127365 DOI: 10.1107/S0108767378096865  0.615
1993 Xie X, Harrison D, Schlichting I, Sweet R, Kalabokis VN, Szent-Gyorgyi AG, Cohen C. Structure of the regulatory domain of scallop myosin at 2.8 Å resolution Acta Crystallographica Section a Foundations of Crystallography. 49: c109-c109. DOI: 10.1107/S0108767378096865  0.522
1992 Singer PT, Carty RP, Berman LE, Schlichting I, Stock A, Smalas A, Cai Z, Mangel WF, Jones KW, Sweet RM. Laue diffraction as a tool in dynamic studies: hydrolysis of a transiently stable intermediate in catalysis by trypsin Philosophical Transactions - Royal Society. Mathematical, Physical and Engineering Sciences. 340: 285-300. DOI: 10.1098/Rsta.1992.0067  0.571
1992 Scheidig AJ, Pai EF, Schlichting I, Corrie JET, Reid GP, Wittinghofer A, Goody RS, Liljas A, Moffat K. Time-resolved crystallography on H-ras p21 Philosophical Transactions - Royal Society. Mathematical, Physical and Engineering Sciences. 340: 263-272. DOI: 10.1098/Rsta.1992.0065  0.32
1990 Schlichting I, John J, Frech M, Chardin P, Wittinghofer A, Zimmermann H, Rösch P. Proton NMR studies of transforming and nontransforming H-ras p21 mutants. Biochemistry. 29: 504-11. PMID 2405906 DOI: 10.1021/bi00454a026  0.683
1990 Reinstein J, Vetter IR, Schlichting I, Rösch P, Wittinghofer A, Goody RS. Fluorescence and NMR investigations on the ligand binding properties of adenylate kinases. Biochemistry. 29: 7440-50. PMID 2223775 DOI: 10.1021/bi00484a013  0.681
1990 Krengel U, Schlichting I, Scherer A, Schumann R, Frech M, John J, Kabsch W, Pai EF, Wittinghofer A. Three-dimensional structures of H-ras p21 mutants: Molecular basis for their inability to function as signal switch molecules Cell. 62: 539-548. PMID 2199064 DOI: 10.1016/0092-8674(90)90018-A  0.302
1990 Schlichting I, Almo SC, Rapp G, Wilson K, Petratos K, Lentfer A, Wittinghofer A, Kabsch W, Pai EF, Petsko GA, Goody RS. Time-resolved X-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis Nature. 345: 309-315. PMID 2111463 DOI: 10.1038/345309A0  0.62
1989 Schlichting I, Rapp G, John J, Wittinghofer A, Pai EF, Goody RS. Biochemical and crystallographic characterization of a complex of c-Ha-ras p21 and caged GTP with flash photolysis Proceedings of the National Academy of Sciences of the United States of America. 86: 7687-7690. PMID 2682619  0.326
1989 John J, Schlichting I, Schiltz E, Rösch P, Wittinghofer A. C-terminal truncation of p21H preserves crucial kinetic and structural properties. The Journal of Biological Chemistry. 264: 13086-92. PMID 2502546  0.693
1988 Schlichting I, Wittinghofer A, Rösch P. Proton NMR studies of the GDP.Mg2+ complex of the Ha-ras oncogene product p21. Biochemical and Biophysical Research Communications. 150: 444-8. PMID 3276311 DOI: 10.1016/0006-291X(88)90540-2  0.682
1986 Rösch P, Wittinghofer A, Tucker J, Sczakiel G, Leberman R, Schlichting I. 31P-NMR spectra of the Ha-ras p21.nucleotide complexes. Biochemical and Biophysical Research Communications. 135: 549-55. PMID 3485974 DOI: 10.1016/0006-291X(86)90029-X  0.665
1986 Klaus W, Schlichting I, Goody RS, Wittinghofer A, Rösch P, Holmes KC. 31P-NMR studies on ATP X Mg2+, p21 X nucleotide, and adenylate kinase X nucleotide complexes. Chemical shifts, rate and equilibrium constants. Biological Chemistry Hoppe-Seyler. 367: 781-6. PMID 3021182 DOI: 10.1515/Bchm3.1986.367.2.781  0.725
Show low-probability matches.