Year |
Citation |
Score |
2005 |
Brown AM. HERG block, QT liability and sudden cardiac death. Novartis Foundation Symposium. 266: 118-31; discussion 1. PMID 16050265 DOI: 10.1002/047002142X.Ch10 |
0.318 |
|
2005 |
Ficker E, Dennis A, Kuryshev Y, Wible BA, Brown AM. HERG channel trafficking. Novartis Foundation Symposium. 266: 57-69; discussion 70. PMID 16050262 DOI: 10.1002/047002142X.Ch6 |
0.377 |
|
2004 |
Kirsch GE, Trepakova ES, Brimecombe JC, Sidach SS, Erickson HD, Kochan MC, Shyjka LM, Lacerda AE, Brown AM. Variability in the measurement of hERG potassium channel inhibition: effects of temperature and stimulus pattern. Journal of Pharmacological and Toxicological Methods. 50: 93-101. PMID 15385083 DOI: 10.1016/j.vascn.2004.06.003 |
0.323 |
|
2004 |
Ficker E, Kuryshev YA, Dennis AT, Obejero-Paz C, Wang L, Hawryluk P, Wible BA, Brown AM. Mechanisms of arsenic-induced prolongation of cardiac repolarization. Molecular Pharmacology. 66: 33-44. PMID 15213294 DOI: 10.1124/mol.66.1.33 |
0.339 |
|
2003 |
Ficker E, Dennis AT, Wang L, Brown AM. Role of the cytosolic chaperones Hsp70 and Hsp90 in maturation of the cardiac potassium channel HERG. Circulation Research. 92: e87-100. PMID 12775586 DOI: 10.1161/01.RES.0000079028.31393.15 |
0.325 |
|
2002 |
Wible BA, Wang L, Kuryshev YA, Basu A, Haldar S, Brown AM. Increased K+ efflux and apoptosis induced by the potassium channel modulatory protein KChAP/PIAS3beta in prostate cancer cells. The Journal of Biological Chemistry. 277: 17852-62. PMID 11877452 DOI: 10.1074/jbc.M201689200 |
0.324 |
|
2002 |
Ficker E, Obejero-Paz CA, Zhao S, Brown AM. The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutations. The Journal of Biological Chemistry. 277: 4989-98. PMID 11741928 DOI: 10.1074/jbc.M107345200 |
0.395 |
|
2001 |
Kuryshev YA, Wible BA, Gudz TI, Ramirez AN, Brown AM. KChAP/Kvbeta1.2 interactions and their effects on cardiac Kv channel expression. American Journal of Physiology. Cell Physiology. 281: C290-9. PMID 11401852 DOI: 10.1152/Ajpcell.2001.281.1.C290 |
0.399 |
|
2000 |
Ficker E, Dennis AT, Obejero-Paz CA, Castaldo P, Taglialatela M, Brown AM. Retention in the endoplasmic reticulum as a mechanism of dominant-negative current suppression in human long QT syndrome Journal of Molecular and Cellular Cardiology. 32: 2327-2337. PMID 11113008 DOI: 10.1006/jmcc.2000.1263 |
0.37 |
|
2000 |
Bianchi L, Priori SG, Napolitano C, Surewicz KA, Dennis AT, Memmi M, Schwartz PJ, Brown AM. Mechanisms of I(Ks) suppression in LQT1 mutants. American Journal of Physiology. Heart and Circulatory Physiology. 279: H3003-11. PMID 11087258 DOI: 10.1152/Ajpheart.2000.279.6.H3003 |
0.513 |
|
2000 |
Napolitano C, Schwartz PJ, Brown AM, Ronchetti E, Bianchi L, Pinnavaia A, Acquaro G, Priori SG. Evidence for a cardiac ion channel mutation underlying drug-induced QT prolongation and life-threatening arrhythmias. Journal of Cardiovascular Electrophysiology. 11: 691-6. PMID 10868744 DOI: 10.1111/J.1540-8167.2000.Tb00033.X |
0.419 |
|
1999 |
Kuryshev YA, Brittenham GM, Fujioka H, Kannan P, Shieh CC, Cohen SA, Brown AM. Decreased sodium and increased transient outward potassium currents in iron-loaded cardiac myocytes: Implications for the arrhythmogenesis of human siderotic heart disease Circulation. 100: 675-683. PMID 10441107 DOI: 10.1161/01.Cir.100.6.675 |
0.31 |
|
1999 |
Kiehn J, Lacerda AE, Brown AM. Pathways of HERG inactivation American Journal of Physiology - Heart and Circulatory Physiology. 277: H199-H210. PMID 10409198 DOI: 10.1152/Ajpheart.1999.277.1.H199 |
0.419 |
|
1999 |
Bianchi L, Shen Z, Dennis AT, Priori SG, Napolitano C, Ronchetti E, Bryskin R, Schwartz PJ, Brown AM. Cellular dysfunction of LQT5-minK mutants: abnormalities of IKs, IKr and trafficking in long QT syndrome. Human Molecular Genetics. 8: 1499-507. PMID 10400998 DOI: 10.1093/Hmg/8.8.1499 |
0.517 |
|
1999 |
Bianchi L, Priori SG, Shen Z, Dennis AT, Napolitano C, Ronchetti E, Bryskin R, Schwartz PJ, Brown AM. Corrigendum: Cellular dysfunction of LQT5-minK mutants: Abnormalities of IKs, IKr and trafficking in long QT syndrome (Human Molecular Genetics (1999) 8 (1499-1507)) Human Molecular Genetics. 8: 2335. DOI: 10.1093/Hmg/8.12.2335 |
0.428 |
|
1998 |
Accili EA, Kuryshev YA, Wible BA, Brown AM. Separable effects of human Kvbeta1.2 N- and C-termini on inactivation and expression of human Kv1.4. The Journal of Physiology. 512: 325-36. PMID 9763623 DOI: 10.1111/j.1469-7793.1998.325be.x |
0.347 |
|
1998 |
Kramer JW, Post MA, Brown AM, Kirsch GE. Modulation of potassium channel gating by coexpression of Kv2.1 with regulatory Kv5.1 or Kv6.1 alpha-subunits. The American Journal of Physiology. 274: C1501-10. PMID 9696692 DOI: 10.1152/Ajpcell.1998.274.6.C1501 |
0.371 |
|
1998 |
Priori SG, Schwartz PJ, Napolitano C, Bianchi L, Dennis A, De Fusco M, Brown AM, Casari G. A recessive variant of the Romano-Ward long-QT syndrome? Circulation. 97: 2420-5. PMID 9641694 DOI: 10.1161/01.Cir.97.24.2420 |
0.486 |
|
1998 |
Schwalbe RA, Bianchi L, Accili EA, Brown AM. Functional consequences of ROMK mutants linked to antenatal Bartter's syndrome and implications for treatment. Human Molecular Genetics. 7: 975-80. PMID 9580661 DOI: 10.1093/Hmg/7.6.975 |
0.499 |
|
1998 |
Wible BA, Yang Q, Kuryshev YA, Accili EA, Brown AM. Cloning and expression of a novel K+ channel regulatory protein, KChAP. The Journal of Biological Chemistry. 273: 11745-51. PMID 9565597 DOI: 10.1074/jbc.273.19.11745 |
0.399 |
|
1998 |
Ficker E, Jarolimek W, Johann K, Baumann A, Brown AM. Molecular determinants of dofetilide block of HERG K+ channels Circulation Research. 82: 386-395. PMID 9486667 DOI: 10.1161/01.Res.82.3.386 |
0.38 |
|
1997 |
Pascual JM, Shieh CC, Kirsch GE, Brown AM. Contribution of the NH2 terminus of Kv2.1 to channel activation American Journal of Physiology - Cell Physiology. 273: C1849-C1858. PMID 9435489 DOI: 10.1152/Ajpcell.1997.273.6.C1849 |
0.39 |
|
1997 |
Rampe D, Roy ML, Dennis A, Brown AM. A mechanism for the proarrhythmic effects of cisapride (Propulsid): High affinity blockade of the human cardiac potassium channel HERG Febs Letters. 417: 28-32. PMID 9395068 DOI: 10.1016/S0014-5793(97)01249-0 |
0.389 |
|
1997 |
Accili EA, Kiehn J, Wible BA, Brown AM. Interactions among inactivating and noninactivating Kvbeta subunits, and Kvalpha1.2, produce potassium currents with intermediate inactivation. The Journal of Biological Chemistry. 272: 28232-6. PMID 9353274 DOI: 10.1074/jbc.272.45.28232 |
0.382 |
|
1997 |
Accili EA, Kiehn J, Yang Q, Wang Z, Brown AM, Wible BA. Separable Kvbeta subunit domains alter expression and gating of potassium channels. The Journal of Biological Chemistry. 272: 25824-31. PMID 9325312 DOI: 10.1074/jbc.272.41.25824 |
0.394 |
|
1997 |
Schwalbe RA, Bianchi L, Brown AM. Mapping the kidney potassium channel ROMK1. Glycosylation of the pore signature sequence and the COOH terminus. The Journal of Biological Chemistry. 272: 25217-23. PMID 9312136 DOI: 10.1074/Jbc.272.40.25217 |
0.516 |
|
1996 |
Taglialatela M, Ongini E, Brown AM, Di Renzo G, Annunziato L. Felbamate inhibits cloned voltage-dependent Na+ channels from human and rat brain European Journal of Pharmacology. 316: 373-377. PMID 8982710 DOI: 10.1016/S0014-2999(96)00802-3 |
0.373 |
|
1996 |
Post MA, Kirsch GE, Brown AM. Kv2.1 and electrically silent Kv6.1 potassium channel subunits combine and express a novel current Febs Letters. 399: 177-182. PMID 8980147 DOI: 10.1016/S0014-5793(96)01316-6 |
0.401 |
|
1996 |
Kiehn J, Lacerda AE, Wible B, Brown AM. Molecular physiology and pharmacology of HERG. Single-channel currents and block by dofetilide. Circulation. 94: 2572-9. PMID 8921803 DOI: 10.1161/01.Cir.94.10.2572 |
0.408 |
|
1996 |
Schwalbe RA, Wang Z, Bianchi L, Brown AM. Novel sites of N-glycosylation in ROMK1 reveal the putative pore-forming segment H5 as extracellular. The Journal of Biological Chemistry. 271: 24201-6. PMID 8798662 DOI: 10.1074/Jbc.271.39.24201 |
0.493 |
|
1996 |
Roy ML, Dumaine R, Brown AM. HERG, a primary human ventricular target of the nonsedating antihistamine terfenadine Circulation. 94: 817-823. PMID 8772706 DOI: 10.1161/01.Cir.94.4.817 |
0.308 |
|
1996 |
Priori SG, Napolitano C, Cantù F, Brown AM, Schwartz PJ. Differential response to Na+ channel blockade, beta-adrenergic stimulation, and rapid pacing in a cellular model mimicking the SCN5A and HERG defects present in the long-QT syndrome. Circulation Research. 78: 1009-15. PMID 8635231 DOI: 10.1161/01.Res.78.6.1009 |
0.356 |
|
1996 |
Bianchi L, Roy ML, Taglialatela M, Lundgren DW, Brown AM, Ficker E. Regulation by spermine of native inward rectifier K+ channels in RBL-1 cells. The Journal of Biological Chemistry. 271: 6114-21. PMID 8626398 DOI: 10.1074/Jbc.271.11.6114 |
0.565 |
|
1996 |
Dumaine R, Wang Q, Keating MT, Hartmann HA, Schwartz PJ, Brown AM, Kirsch GE. Multiple mechanisms of Na+ channel--linked long-QT syndrome. Circulation Research. 78: 916-24. PMID 8620612 DOI: 10.1161/01.Res.78.5.916 |
0.398 |
|
1996 |
Dumaine R, Hartmann HA, Leishman DJ, Brown AM, Galvan M. Actions of dolasetron and its major metabolite on guinea-pig papillary muscle fibres and the α-subunit of human heart sodium channels expressed in Xenopus oocytes Drug Development Research. 37: 223-230. DOI: 10.1002/(SICI)1098-2299(199604)37:4<223::AID-DDR4>3.0.CO;2-N |
0.381 |
|
1995 |
Taglialatela M, Ficker E, Wible B, Brown AM. Pharmacological implications of inward rectifier K+ channels regulation by cytoplasmic polyamines. Pharmacological Research. 32: 335-44. PMID 8736484 DOI: 10.1016/S1043-6618(05)80038-6 |
0.383 |
|
1995 |
Taglialatela M, Brown AM. Structural motifs underlying voltage-dependent K+ channel function Kidney International. 48: 918-922. PMID 8569100 DOI: 10.1038/Ki.1995.372 |
0.388 |
|
1995 |
Taglialatela M, Ficker E, Wible BA, Brown AM. C-terminus determinants for Mg2+ and polyamine block of the inward rectifier K+ channel IRK1. The Embo Journal. 14: 5532-41. PMID 8521810 DOI: 10.1002/J.1460-2075.1995.Tb00240.X |
0.36 |
|
1995 |
Schwartz PJ, Priori SG, Locati EH, Napolitano C, Cantù F, Towbin JA, Keating MT, Hammoude H, Brown AM, Chen LS. Long QT syndrome patients with mutations of the SCN5A and HERG genes have differential responses to Na+ channel blockade and to increases in heart rate. Implications for gene-specific therapy. Circulation. 92: 3381-6. PMID 8521555 DOI: 10.1161/01.Cir.92.12.3381 |
0.315 |
|
1995 |
Wible BA, De Biasi M, Majumder K, Taglialatela M, Brown AM. Cloning and functional expression of an inwardly rectifying K+ channel from human atrium. Circulation Research. 76: 343-50. PMID 7859381 |
0.593 |
|
1995 |
Schwalbe RA, Wang Z, Wible BA, Brown AM. Potassium channel structure and function as reported by a single glycosylation sequon. The Journal of Biological Chemistry. 270: 15336-40. PMID 7797521 DOI: 10.1074/Jbc.270.25.15336 |
0.384 |
|
1995 |
Pascual JM, Shieh CC, Kirsch GE, Brown AM. K+ pore structure revealed by reporter cysteines at inner and outer surfaces Neuron. 14: 1055-1063. PMID 7748553 DOI: 10.1016/0896-6273(95)90344-5 |
0.315 |
|
1995 |
TAGLIALATELA M, FICKER E, WIBLE B, BROWN A. Cell engineering and expression of ion channels Pharmacological Research. 31: 18-18. DOI: 10.1016/1043-6618(95)86330-3 |
0.313 |
|
1994 |
Wible BA, Taglialatela M, Ficker E, Brown AM. Gating of inwardly rectifying K+ channels localized to a single negatively charged residue. Nature. 371: 246-9. PMID 8078584 DOI: 10.1038/371246a0 |
0.384 |
|
1994 |
Brown AM, Schwindt PC, Crill WE. Different voltage dependence of transient and persistent Na+ currents is compatible with modal-gating hypothesis for sodium channels. Journal of Neurophysiology. 71: 2562-5. PMID 7931536 DOI: 10.1152/Jn.1994.71.6.2562 |
0.302 |
|
1994 |
Wible BA, Brown AM. Function and structure of voltage-dependent potassium channels Drug Development Research. 33: 225-234. DOI: 10.1002/ddr.430330306 |
0.411 |
|
1993 |
Brown AM, Drewe JA, Hartmann HA, Taglialatela M, De Biasi M, Soman K, Kirsch GE. The potassium pore and its regulation. Annals of the New York Academy of Sciences. 707: 74-80. PMID 9137543 |
0.509 |
|
1993 |
De Biasi M, Hartmann HA, Drewe JA, Taglialatela M, Brown AM, Kirsch GE. Inactivation determined by a single site in K+ pores. PflüGers Archiv : European Journal of Physiology. 422: 354-63. PMID 8437886 DOI: 10.1007/BF00374291 |
0.595 |
|
1993 |
Critz SD, Wible BA, Lopez HS, Brown AM. Stable expression and regulation of a rat brain K+ channel. Journal of Neurochemistry. 60: 1175-8. PMID 8436968 DOI: 10.1111/J.1471-4159.1993.Tb03273.X |
0.407 |
|
1993 |
Rampe D, Wible B, Fedida D, Dage RC, Brown AM. Verapamil blocks a rapidly activating delayed rectifier K+ channel cloned from human heart. Molecular Pharmacology. 44: 642-8. PMID 8371716 |
0.307 |
|
1993 |
Brown AM. Functional bases for interpreting amino acid sequences of voltage-dependent K+ channels Annual Review of Biophysics and Biomolecular Structure. 22: 173-198. PMID 8347988 DOI: 10.1146/Annurev.Bb.22.060193.001133 |
0.379 |
|
1993 |
Kirsch GE, Drewe JA, De Biasi M, Hartmann HA, Brown AM. Functional interactions between K+ pore residues located in different subunits. The Journal of Biological Chemistry. 268: 13799-804. PMID 8314749 |
0.558 |
|
1993 |
De Biasi M, Drewe JA, Kirsch GE, Brown AM. Histidine substitution identifies a surface position and confers Cs+ selectivity on a K+ pore. Biophysical Journal. 65: 1235-42. PMID 8241404 DOI: 10.1016/S0006-3495(93)81154-8 |
0.591 |
|
1993 |
Taglialatela M, Drewe JA, Kirsch GE, De Biasi M, Hartmann HA, Brown AM. Regulation of K+/Rb+ selectivity and internal TEA blockade by mutations at a single site in K+ pores. PflüGers Archiv : European Journal of Physiology. 423: 104-12. PMID 7683786 DOI: 10.1007/BF00374967 |
0.575 |
|
1993 |
Brown AM. Membrane-delimited cell signaling complexes: Direct ion channel regulation by G Proteins The Journal of Membrane Biology. 131: 93-104. PMID 7680074 DOI: 10.1007/BF02791318 |
0.349 |
|
1992 |
Kirsch GE, Drewe JA, Hartmann HA, Taglialatela M, de Biasi M, Brown AM, Joho RH. Differences between the deep pores of K+ channels determined by an interacting pair of nonpolar amino acids. Neuron. 8: 499-505. PMID 1550675 DOI: 10.1016/0896-6273(92)90278-L |
0.608 |
|
1992 |
Possani LD, Martin BM, Yatani A, Mochca-Morales J, Zamudio FZ, Gurrola GB, Brown AM. Isolation and physiological characterization of taicatoxin, a complex toxin with specific effects on calcium channels. Toxicon. 30: 1343-1364. PMID 1485334 DOI: 10.1016/0041-0101(92)90511-3 |
0.364 |
|
1992 |
Brown AM. Ion channels in action potential generation Hospital Practice. 27: 125-130. PMID 1383247 DOI: 10.1080/21548331.1992.11705513 |
0.355 |
|
1992 |
BROWN A. Modulators and blockers of ion channel pores Pharmacological Research. 26: 1. DOI: 10.1016/1043-6618(92)90714-M |
0.336 |
|
1991 |
Hartmann HA, Kirsch GE, Drewe JA, Taglialatela M, Joho RH, Brown AM. Exchange of conduction pathways between two related K+ channels. Science (New York, N.Y.). 251: 942-4. PMID 2000495 DOI: 10.1126/science.2000495 |
0.387 |
|
1991 |
Kirsch GE, Drewe JA, Verma S, Brown AM, Joho RH. Electrophysiological characterization of a new member of the RCK family of rat brain K+ channels. Febs Letters. 278: 55-60. PMID 1993474 DOI: 10.1016/0014-5793(91)80082-E |
0.383 |
|
1991 |
Kirsch GE, Taglialatela M, Brown AM. Internal and external TEA block in single cloned K+ channels. The American Journal of Physiology. 261: C583-90. PMID 1928322 DOI: 10.1152/AJPCELL.1991.261.4.C583 |
0.306 |
|
1991 |
Brown AM, Yatani A, Kirsch G, Okabe K, VanDongen AM, Birnbaumer L. Control of K+ channels by G proteins. Journal of Bioenergetics and Biomembranes. 23: 499-507. PMID 1917906 DOI: 10.1007/BF00785808 |
0.372 |
|
1991 |
Lopez HS, Brown AM. Correlation between G protein activation and reblocking kinetics of Ca2+ channel currents in rat sensory neurons. Neuron. 7: 1061-8. PMID 1662518 DOI: 10.1016/0896-6273(91)90350-9 |
0.349 |
|
1991 |
Okabe K, Yatani A, Brown AM. The nature and origin of spontaneous noise in G protein-gated ion channels. The Journal of General Physiology. 97: 1279-93. PMID 1651979 DOI: 10.1085/JGP.97.6.1279 |
0.401 |
|
1991 |
Lacerda AE, Kim HS, Ruth P, Perez-Reyes E, Flockerzi V, Hofmann F, Birnbaumer L, Brown AM. Normalization of current kinetics by interaction between the alpha 1 and beta subunits of the skeletal muscle dihydropyridine-sensitive Ca2+ channel. Nature. 352: 527-30. PMID 1650913 DOI: 10.1038/352527a0 |
0.314 |
|
1990 |
VanDongen AM, Frech GC, Drewe JA, Joho RH, Brown AM. Alteration and restoration of K+ channel function by deletions at the N- and C-termini. Neuron. 5: 433-43. PMID 2206531 DOI: 10.1016/0896-6273(90)90082-Q |
0.392 |
|
1990 |
Birnbaumer L, Abramowitz J, Yatani A, Okabe K, Mattera R, Graf R, Sanford J, Codina J, Brown AM. Roles of G proteins in coupling of receptors to ionic channels and other effector systems. Critical Reviews in Biochemistry and Molecular Biology. 25: 225-44. PMID 2171876 DOI: 10.3109/10409239009090610 |
0.378 |
|
1990 |
Yatani A, Brown AM. Regulation of cardiac pacemaker current I(f) in excised membranes from sinoatrial node cells American Journal of Physiology - Heart and Circulatory Physiology. 258. PMID 2163222 DOI: 10.1152/AJPHEART.1990.258.6.H1947 |
0.355 |
|
1990 |
Joho RH, Moorman JR, VanDongen AM, Kirsch GE, Silberberg H, Schuster G, Brown AM. Toxin and kinetic profile of rat brain type III sodium channels expressed in Xenopus oocytes. Brain Research. Molecular Brain Research. 7: 105-13. PMID 2160038 DOI: 10.1016/0169-328X(90)90087-T |
0.387 |
|
1990 |
Marchetti C, Childs GV, Brown AM. Voltage-dependent calcium currents in rat gonadotropes separated by centrifugal elutriation. The American Journal of Physiology. 258: E589-96. PMID 2159217 DOI: 10.1152/Ajpendo.1990.258.4.E589 |
0.364 |
|
1990 |
Schubert B, Vandongen AM, Kirsch GE, Brown AM. Inhibition of cardiac Na+ currents by isoproterenol. The American Journal of Physiology. 258: H977-82. PMID 2158748 DOI: 10.1152/AJPHEART.1990.258.4.H977 |
0.399 |
|
1990 |
Moorman JR, Kirsch GE, VanDongen AM, Joho RH, Brown AM. Fast and slow gating of sodium channels encoded by a single mRNA. Neuron. 4: 243-52. PMID 2155011 DOI: 10.1016/0896-6273(90)90099-2 |
0.384 |
|
1990 |
Yatani A, Okabe K, Birnbaumer L, Brown AM. Detergents, dimeric G beta gamma, and eicosanoid pathways to muscarinic atrial K+ channels. The American Journal of Physiology. 258: H1507-14. PMID 2110781 DOI: 10.1152/Ajpheart.1990.258.5.H1507 |
0.355 |
|
1990 |
Birnbaumer L, Yatani A, VanDongen AM, Graf R, Codina J, Okabe K, Mattera R, Brown AM. G protein coupling of receptors to ionic channels and other effector systems. British Journal of Clinical Pharmacology. 30: 13S-22S. PMID 1702677 DOI: 10.1111/J.1365-2125.1990.TB05463.X |
0.308 |
|
1990 |
Brown AM, Birnbaumer L. Ionic channels and their regulation by G protein subunits. Annual Review of Physiology. 52: 197-213. PMID 1691904 DOI: 10.1146/annurev.ph.52.030190.001213 |
0.342 |
|
1989 |
Frech GC, VanDongen AM, Schuster G, Brown AM, Joho RH. A novel potassium channel with delayed rectifier properties isolated from rat brain by expression cloning. Nature. 340: 642-5. PMID 2770868 DOI: 10.1038/340642a0 |
0.391 |
|
1989 |
Moorman JR, Kirsch GE, Lacerda AE, Brown AM. Angiotensin II modulates cardiac Na+ channels in neonatal rat. Circulation Research. 65: 1804-9. PMID 2555083 DOI: 10.1161/01.RES.65.6.1804 |
0.365 |
|
1989 |
Mattera R, Graziano MP, Yatani A, Zhou Z, Graf R, Codina J, Birnbaumer L, Gilman AG, Brown AM. Splice variants of the alpha subunit of the G protein Gs activate both adenylyl cyclase and calcium channels. Science (New York, N.Y.). 243: 804-7. PMID 2536957 DOI: 10.1126/Science.2536957 |
0.308 |
|
1989 |
Kirsch GE, Skattebøl A, Possani LD, Brown AM. Modification of Na channel gating by an alpha scorpion toxin from Tityus serrulatus. The Journal of General Physiology. 93: 67-83. PMID 2536799 DOI: 10.1085/JGP.93.1.67 |
0.314 |
|
1989 |
Lacerda AE, Brown AM. Nonmodal gating of cardiac calcium channels as revealed by dihydropyridines Journal of General Physiology. 93: 1243-1273. PMID 2475580 DOI: 10.1085/JGP.93.6.1243 |
0.383 |
|
1989 |
Brown AM, Birnbaumer L. Ion channels and G proteins. Hospital Practice (Office Ed.). 24: 189-93, 198, 202-4. PMID 2473087 DOI: 10.1080/21548331.1989.11703753 |
0.332 |
|
1989 |
Skattebøl A, Brown AM, Triggle DJ. Homologous regulation of voltage-dependent calcium channels by 1,4-dihydropyridines. Biochemical and Biophysical Research Communications. 160: 929-36. PMID 2470374 DOI: 10.1016/0006-291X(89)92524-2 |
0.388 |
|
1989 |
Brown AM, Yatani A, Codina J, Birnbaumer L. G protein-gated channels. A third major category of ionic channels. American Journal of Hypertension. 2: 124-7. PMID 2465009 DOI: 10.1093/Ajh/2.2.124 |
0.353 |
|
1988 |
Yatani A, Mattera R, Codina J, Graf R, Okabe K, Padrell E, Iyengar R, Brown AM, Birnbaumer L. The G protein-gated atrial K+ channel is stimulated by three distinct Gi alpha-subunits. Nature. 336: 680-2. PMID 3143915 DOI: 10.1038/336680a0 |
0.317 |
|
1988 |
Martin BM, Carbone E, Yatani A, Brown AM, Ramírez AN, Gurrola GB, Possani LD. Amino acid sequence and physiological characterization of toxins from the venom of the scorpion Centruroides limpidus tecomanus Hoffmann. Toxicon : Official Journal of the International Society On Toxinology. 26: 785-94. PMID 2849217 DOI: 10.1016/0041-0101(88)90319-4 |
0.321 |
|
1988 |
Imoto Y, Yatani A, Reeves JP, Codina J, Birnbaumer L, Brown AM. Alpha-subunit of Gs directly activates cardiac calcium channels in lipid bilayers. The American Journal of Physiology. 255: H722-8. PMID 2845814 DOI: 10.1152/ajpheart.1988.255.4.H722 |
0.346 |
|
1988 |
Lacerda AE, Rampe D, Brown AM. Effects of protein kinase C activators on cardiac Ca2+ channels. Nature. 335: 249-51. PMID 2457814 DOI: 10.1038/335249a0 |
0.358 |
|
1988 |
Marchetti C, Premont RT, Brown AM. A whole-cell and single-channel study of the voltage-dependent outward potassium current in avian hepatocytes. The Journal of General Physiology. 91: 255-74. PMID 2453605 DOI: 10.1085/Jgp.91.2.255 |
0.411 |
|
1988 |
Yatani A, Kirsch GE, Possani LD, Brown AM. Effects of New World scorpion toxins on single-channel and whole cell cardiac sodium currents. The American Journal of Physiology. 254: H443-51. PMID 2450477 DOI: 10.1152/AJPHEART.1988.254.3.H443 |
0.41 |
|
1988 |
Yatani A, Kunze DL, Brown AM. Effects of dihydropyridine calcium channel modulators on cardiac sodium channels. The American Journal of Physiology. 254: H140-7. PMID 2447804 DOI: 10.1152/Ajpheart.1988.254.1.H140 |
0.313 |
|
1988 |
Marchetti C, Brown AM. Protein kinase activator 1-oleoyl-2-acetyl-sn-glycerol inhibits two types of calcium currents in GH3 cells. The American Journal of Physiology. 254: C206-10. PMID 2447796 DOI: 10.1152/AJPCELL.1988.254.1.C206 |
0.316 |
|
1987 |
Marchetti C, Childs GV, Brown AM. Membrane currents of identified isolated rat corticotropes and gonadotropes. The American Journal of Physiology. 252: E340-6. PMID 3548430 DOI: 10.1152/Ajpendo.1987.252.3.E340 |
0.319 |
|
1987 |
Moorman JR, Zhou Z, Kirsch GE, Lacerda AE, Caffrey JM, Lam DM, Joho RH, Brown AM. Expression of single calcium channels in Xenopus oocytes after injection of mRNA from rat heart. The American Journal of Physiology. 253: H985-91. PMID 2444117 DOI: 10.1152/AJPHEART.1987.253.4.H985 |
0.403 |
|
1987 |
Huang LY, Yatani A, Brown AM. The properties of batrachotoxin-modified cardiac Na channels, including state-dependent block by tetrodotoxin. The Journal of General Physiology. 90: 341-60. PMID 2443605 DOI: 10.1085/JGP.90.3.341 |
0.422 |
|
1987 |
Codina J, Grenet D, Yatani A, Birnbaumer L, Brown AM. Hormonal regulation of pituitary GH3 cell K+ channels by Gk is mediated by its alpha-subunit. Febs Letters. 216: 104-6. PMID 2438161 DOI: 10.1016/0014-5793(87)80765-2 |
0.345 |
|
1987 |
Birnbaumer L, Brown AM. G protein opening of K+ channels. Nature. 327: 21-2. PMID 2437458 DOI: 10.1038/327021a0 |
0.345 |
|
1987 |
Childs GV, Marchetti C, Brown AM. Involvement of sodium channels and two types of calcium channels in the regulation of adrenocorticotropin release. Endocrinology. 120: 2059-69. PMID 2436894 DOI: 10.1210/Endo-120-5-2059 |
0.352 |
|
1987 |
Josephson IR, Brown AM. Inwardly rectifying single-channel and whole cell K+ currents in rat ventricular myocytes. The Journal of Membrane Biology. 94: 19-35. PMID 2433453 DOI: 10.1007/BF01901010 |
0.418 |
|
1986 |
Brown AM, Kunze DL, Yatani A. Dual effects of dihydropyridines on whole cell and unitary calcium currents in single ventricular cells of guinea-pig. The Journal of Physiology. 379: 495-514. PMID 2435896 DOI: 10.1113/jphysiol.1986.sp016266 |
0.367 |
|
1986 |
Brown AM, Kunze DL, Lux HD. Single calcium channels and their inactivation. Membrane Biochemistry. 6: 73-81. PMID 2427920 DOI: 10.3109/09687688609065444 |
0.365 |
|
1986 |
Caffrey JM, Josephson IR, Brown AM. Calcium channels of amphibian stomach and mammalian aorta smooth muscle cells. Biophysical Journal. 49: 1237-42. PMID 2424518 DOI: 10.1016/S0006-3495(86)83753-5 |
0.35 |
|
1986 |
BROWN A, KUNZE D, LACERDA A. Sodium and calcium single channel currents in neonatal cardiac myocytes* Journal of Molecular and Cellular Cardiology. 18: 15-15. DOI: 10.1016/S0022-2828(86)80076-1 |
0.358 |
|
1985 |
Hamilton SL, Yatani A, Hawkes MJ, Redding K, Brown AM. Atrotoxin: A specific agonist for calcium currents in heart Science. 229: 182-184. PMID 3160111 DOI: 10.1126/SCIENCE.3160111 |
0.398 |
|
1985 |
Kunze DL, Lacerda AE, Wilson DL, Brown AM. Cardiac Na currents and the inactivating, reopening, and waiting properties of single cardiac Na channels. The Journal of General Physiology. 86: 691-719. PMID 2415670 DOI: 10.1085/JGP.86.5.691 |
0.427 |
|
1985 |
Wilson DL, Brown AM. Effect of Limited Interval Resolution on Single Channel Measurements with Application to Ca Channels Ieee Transactions On Biomedical Engineering. 32: 786-797. PMID 2414209 DOI: 10.1109/Tbme.1985.325494 |
0.378 |
|
1985 |
Williams JS, Grupp IL, Grupp G, Vaghy PL, Dumont L, Schwartz A, Yatani A, Hamilton S, Brown AM. Profile of the oppositely acting enantiomers of the dihydropyridine 202-791 in cardiac preparations: receptor binding, electrophysiological, and pharmacological studies. Biochemical and Biophysical Research Communications. 131: 13-21. PMID 2412552 DOI: 10.1016/0006-291X(85)91763-2 |
0.331 |
|
1984 |
Brown AM, Wilson DL, Lux HD. Activation of calcium channels. Biophysical Journal. 45: 125-7. PMID 19431535 DOI: 10.1016/S0006-3495(84)84134-X |
0.354 |
|
1984 |
Brown AM, Lux HD, Wilson DL. Activation and inactivation of single calcium channels in snail neurons. The Journal of General Physiology. 83: 751-69. PMID 6330277 DOI: 10.1085/Jgp.83.5.751 |
0.384 |
|
1984 |
Yatani A, Brown AM, Akaike N. Effect of extracellular pH on sodium current in isolated, single rat ventricular cells The Journal of Membrane Biology. 78: 163-168. PMID 6325701 DOI: 10.1007/Bf01869203 |
0.342 |
|
1984 |
Brown AM, Tsuda Y, Wilson DL. A description of activation and conduction in calcium channels based on tail and turn-on current measurements in the snail. The Journal of Physiology. 344: 549-83. PMID 6317852 DOI: 10.1113/jphysiol.1983.sp014956 |
0.355 |
|
1984 |
Brown AM, Kunze DL, Yatani A. The agonist effect of dihydropyridines on Ca channels. Nature. 311: 570-2. PMID 6207438 DOI: 10.1038/311570A0 |
0.397 |
|
1983 |
Thoren P, Andresen MC, Brown AM. Resetting of aortic baroreceptors with non-myelinated afferent fibers in spontaneously hypertensive rats. Acta Physiologica Scandinavica. 117: 91-7. PMID 6858708 DOI: 10.1111/J.1748-1716.1983.Tb07182.X |
0.697 |
|
1983 |
Munch PA, Andresen MC, Brown AM. Rapid resetting of aortic baroreceptors in vitro. The American Journal of Physiology. 244: H672-80. PMID 6846555 DOI: 10.1152/Ajpheart.1983.244.5.H672 |
0.692 |
|
1983 |
Akaike N, Brown AM, Dahl G, Higashi H, Isenberg G, Tsuda Y, Yatani A. Voltage-dependent activation of potassium current in Helix neurones by endogenous cellular calcium. The Journal of Physiology. 334: 309-24. PMID 6408248 DOI: 10.1113/jphysiol.1983.sp014496 |
0.366 |
|
1983 |
Yatani A, Wilson DL, Brown AM. Recovery of Ca currents from inactivation: the roles of Ca influx, membrane potential, and cellular metabolism. Cellular and Molecular Neurobiology. 3: 381-395. PMID 6325014 DOI: 10.1007/Bf00734718 |
0.318 |
|
1983 |
Wilson DL, Morimoto K, Tsuda Y, Brown AM. Interaction between calcium ions and surface charge as it relates to calcium currents. The Journal of Membrane Biology. 72: 117-130. PMID 6304316 DOI: 10.1007/Bf01870319 |
0.341 |
|
1982 |
Thoren P, Andresen MC, Brown AM. Effects of changes in extracellular ionic concentrations on aortic baroreceptors with nonmyelinated afferent fibers. Circulation Research. 50: 413-8. PMID 7060235 DOI: 10.1161/01.Res.50.3.413 |
0.704 |
|
1982 |
Andresen MC, Brown AM. Cellular basis of the photoresponse of an extraretinal photoreceptor. Experientia. 38: 1001-6. PMID 6290258 DOI: 10.1007/Bf01955343 |
0.661 |
|
1982 |
Brown AM, Camerer H, Kunze DL, Lux HD. Similarity of unitary Ca2+ currents in three different species. Nature. 299: 156-8. PMID 6287284 DOI: 10.1038/299156a0 |
0.362 |
|
1982 |
Yatani A, Tsuda Y, Akaike N, Brown AM. Nanomolar concentrations of extracellular ATP activate membrane Ca channels in snail neurones Nature. 296: 169-171. PMID 6278318 DOI: 10.1038/296169A0 |
0.362 |
|
1982 |
Brown AM, Morimoto K, Tsuda Y, wilson DL. Calcium current-dependent and voltage-dependent inactivation of calcium channels in Helix aspersa. The Journal of Physiology. 320: 193-218. PMID 6275075 DOI: 10.1113/jphysiol.1981.sp013944 |
0.376 |
|
1981 |
Lee KS, Hume JR, Giles W, Brown AM. Sodium current depression by lidocaine and quinidine in isolated ventricular cells Nature. 291: 325-327. PMID 7231552 DOI: 10.1038/291325A0 |
0.304 |
|
1980 |
Andresen MC, Brown AM. Baroreceptor function in spontaneously hypertensive rats. Effect of preventing hypertension. Circulation Research. 47: 829-34. PMID 7438333 DOI: 10.1161/01.Res.47.6.829 |
0.694 |
|
1980 |
Andresen MC, Kuraoka S, Brown AM. Baroreceptor function and changes in strain sensitivity in normotensive and spontaneously hypertensive rats. Circulation Research. 47: 821-8. PMID 7438332 DOI: 10.1161/01.Res.47.6.821 |
0.699 |
|
1979 |
Andresen MC, Kuraoka S, Brown AM. Individual and combined actions of calcium, sodium, and potassium ions on baroreceptors in the rat. Circulation Research. 45: 757-63. PMID 498439 DOI: 10.1161/01.Res.45.6.757 |
0.68 |
|
1979 |
Krauhs JM, Andresen MC, Baur PS, Brown AM. Ultrastructure of Aplysia neurons having different degrees of light sensitivity. Journal of Neurobiology. 10: 455-64. PMID 490156 DOI: 10.1002/Neu.480100504 |
0.675 |
|
1979 |
Andresen MC, Brown AM, Yasui S. The role of diffusion in the photoresponse of an extraretinal photoreceptor of Aplysia. The Journal of Physiology. 287: 283-301. PMID 430409 DOI: 10.1113/Jphysiol.1979.Sp012659 |
0.69 |
|
1979 |
Andresen MC, Brown AM. Photoresponses of a sensitive extraretinal photoreceptor in Aplysia. The Journal of Physiology. 287: 267-82. PMID 430406 DOI: 10.1113/Jphysiol.1979.Sp012658 |
0.709 |
|
1979 |
Lee KS, Weeks TA, Kao RL, Akaike N, Brown AM. Sodium current in single heart muscle cells. Nature. 278: 269-71. PMID 423978 DOI: 10.1038/278269a0 |
0.302 |
|
1978 |
Andresen MC, Krauhs JM, Brown AM. Relationship of aortic wall and baroreceptor properties during development in normotensive and spontaneously hypertensive rats. Circulation Research. 43: 728-38. PMID 709739 DOI: 10.1161/01.Res.43.5.728 |
0.696 |
|
1978 |
Akaike N, Fishman HM, Lee KS, Moore LE, Brown AM. The units of calcium conduction in Helix neurones [24] Nature. 274: 379-382. PMID 672962 DOI: 10.1038/274379a0 |
0.349 |
|
1977 |
Lee KS, Akaike N, Brown AM. Trypsin inhibits the action of tetrodotoxin on neurones Nature. 265: 751-753. PMID 859585 DOI: 10.1038/265751A0 |
0.391 |
|
1977 |
Thorén P, Saum WR, Brown AM. Characteristics of rat aortic baroreceptors with nonmedullated afferent nerve fibers. Circulation Research. 40: 231-7. PMID 837469 DOI: 10.1161/01.RES.40.3.231 |
0.314 |
|
1973 |
Brown AM, Brown HM. Light response of a giant Aplysia neuron Journal of General Physiology. 62: 239-254. PMID 4730667 DOI: 10.1085/JGP.62.3.239 |
0.362 |
|
1972 |
Mack Brown H, Brown AM. Ionic basis of the photoresponse of aplysia giant neuron: K+ permeability increase Science. 178: 755-756. PMID 5082839 DOI: 10.1126/science.178.4062.755 |
0.318 |
|
1971 |
Kunze DL, Brown AM. Internal potassium and chloride activities and the effects of acetylcholine on identifiable Aplysia neurones. Nature: New Biology. 229: 229-31. PMID 5279794 DOI: 10.1038/NEWBIO229229A0 |
0.316 |
|
1970 |
Brown AM, Sutton RB, Walker JL. Increased chloride conductance as the proximate cause of hydrogen ion concentration effects in Aplysia neurons. The Journal of General Physiology. 56: 559-82. PMID 5475996 DOI: 10.1085/Jgp.56.5.559 |
0.332 |
|
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