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Paul W. Rothlauf - Publications

Affiliations: 
Harvard Medical School 
Area:
Virology, Immunology
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21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Doyle CA, Busey GW, Iobst WH, Kiessling V, Renken C, Doppalapudi H, Stremska ME, Manjegowda MC, Arish M, Wang W, Naphade S, Kennedy J, Bloyet LM, Thompson CE, Rothlauf PW, et al. Endosomal fusion of pH-dependent enveloped viruses requires ion channel TRPM7. Nature Communications. 15: 8479. PMID 39353909 DOI: 10.1038/s41467-024-52773-w  0.468
2023 Chen H, Lye MF, Gorgulla C, Ficarro SB, Cuny GD, Scott DA, Wu F, Rothlauf PW, Wang X, Fernandez R, Pesola JM, Draga S, Marto JA, Hogle JM, Arthanari H, et al. A small molecule exerts selective antiviral activity by targeting the human cytomegalovirus nuclear egress complex. Plos Pathogens. 19: e1011781. PMID 37976321 DOI: 10.1371/journal.ppat.1011781  0.4
2022 Manangeeswaran M, Ireland DDC, Thacker SG, Lee HN, Kelley-Baker L, Lewkowicz AP, Rothlauf PW, Cornejo Pontelli M, Bloyet LM, Eckhaus MA, Mendoza MI, Whelan S, Verthelyi D. BSL2-compliant lethal mouse model of SARS-CoV-2 and variants of concern to evaluate therapeutics targeting the Spike protein. Frontiers in Immunology. 13: 919815. PMID 35967447 DOI: 10.3389/fimmu.2022.919815  0.52
2022 Bamunuarachchi G, Harastani H, Rothlauf PW, Dai YN, Ellebedy A, Fremont D, Whelan SPJ, Wang D, Boon ACM. Detection of Bourbon Virus-Specific Serum Neutralizing Antibodies in Human Serum in Missouri, USA. Msphere. e0016422. PMID 35607948 DOI: 10.1128/msphere.00164-22  0.375
2022 Son J, Huang S, Zeng Q, Bricker TL, Case JB, Zhou J, Zang R, Liu Z, Chang X, Darling TL, Xu J, Harastani HH, Chen L, Gomez Castro MF, Zhao Y, ... ... Rothlauf PW, et al. JIB-04 Has Broad-Spectrum Antiviral Activity and Inhibits SARS-CoV-2 Replication and Coronavirus Pathogenesis. Mbio. e0337721. PMID 35038906 DOI: 10.1128/mbio.03377-21  0.68
2021 Mahoney M, Damalanka VC, Tartell MA, Chung DH, Lourenço AL, Pwee D, Mayer Bridwell AE, Hoffmann M, Voss J, Karmakar P, Azouz NP, Klingler AM, Rothlauf PW, Thompson CE, Lee M, et al. A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34635581 DOI: 10.1073/pnas.2108728118  0.497
2021 Puray-Chavez M, LaPak KM, Schrank TP, Elliott JL, Bhatt DP, Agajanian MJ, Jasuja R, Lawson DQ, Davis K, Rothlauf PW, Liu Z, Jo H, Lee N, Tenneti K, Eschbach JE, et al. Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell. Cell Reports. 109364. PMID 34214467 DOI: 10.1016/j.celrep.2021.109364  0.404
2021 Mahoney M, Damalanka VC, Tartell MA, Chung DH, Lourenco AL, Pwee D, Mayer Bridwell AE, Hoffmann M, Voss J, Karmakar P, Azouz N, Klingler AM, Rothlauf PW, Thompson CE, Lee M, et al. A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells. Biorxiv : the Preprint Server For Biology. PMID 34131661 DOI: 10.1101/2021.05.06.442935  0.506
2021 Puray-Chavez M, LaPak KM, Schrank TP, Elliott JL, Bhatt DP, Agajanian MJ, Jasuja R, Lawson DQ, Davis K, Rothlauf PW, Jo H, Lee N, Tenneti K, Eschbach JE, Mugisha CS, et al. Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell. Biorxiv : the Preprint Server For Biology. PMID 33688646 DOI: 10.1101/2021.03.01.433431  0.429
2020 Zang R, Case JB, Yutuc E, Ma X, Shen S, Gomez Castro MF, Liu Z, Zeng Q, Zhao H, Son J, Rothlauf PW, Kreutzberger AJB, Hou G, Zhang H, Bose S, et al. Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion. Proceedings of the National Academy of Sciences of the United States of America. PMID 33239446 DOI: 10.1073/pnas.2012197117  0.509
2020 Son J, Huang S, Zeng Q, Bricker TL, Case JB, Zhou J, Zang R, Liu Z, Chang X, Harastani HH, Chen L, Gomez Castro MF, Zhao Y, Kohio HP, Hou G, ... ... Rothlauf PW, et al. Nitazoxanide and JIB-04 have broad-spectrum antiviral activity and inhibit SARS-CoV-2 replication in cell culture and coronavirus pathogenesis in a pig model. Biorxiv : the Preprint Server For Biology. PMID 32995798 DOI: 10.1101/2020.09.24.312165  0.673
2020 Case JB, Rothlauf PW, Chen RE, Kafai NM, Fox JM, Smith BK, Shrihari S, McCune BT, Harvey IB, Keeler SP, Bloyet LM, Zhao H, Ma M, Adams LJ, Winkler ES, et al. Replication-Competent Vesicular Stomatitis Virus Vaccine Vector Protects against SARS-CoV-2-Mediated Pathogenesis in Mice. Cell Host & Microbe. PMID 32798445 DOI: 10.1016/J.Chom.2020.07.018  0.402
2020 Kang YL, Chou YY, Rothlauf PW, Liu Z, Soh TK, Cureton D, Case JB, Chen RE, Diamond MS, Whelan SPJ, Kirchhausen T. Inhibition of PIKfyve kinase prevents infection by Zaire ebolavirus and SARS-CoV-2. Proceedings of the National Academy of Sciences of the United States of America. PMID 32764148 DOI: 10.1073/Pnas.2007837117  0.515
2020 Case JB, Rothlauf PW, Chen RE, Liu Z, Zhao H, Kim AS, Bloyet LM, Zeng Q, Tahan S, Droit L, Ilagan MXG, Tartell MA, Amarasinghe G, Henderson JP, Miersch S, et al. Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2. Cell Host & Microbe. PMID 32735849 DOI: 10.1016/J.Chom.2020.06.021  0.424
2020 Case JB, Rothlauf PW, Chen RE, Liu Z, Zhao H, Kim AS, Bloyet LM, Zeng Q, Tahan S, Droit L, Ilagan MXG, Tartell MA, Amarasinghe GK, Henderson JP, Miersch S, et al. Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2. Ssrn. 3606354. PMID 32714117 DOI: 10.2139/ssrn.3606354  0.328
2020 Case JB, Rothlauf PW, Chen RE, Kafai NM, Fox JM, Shrihari S, McCune BT, Harvey IB, Smith B, Keeler SP, Bloyet LM, Winkler ES, Holtzman MJ, Fremont DH, Whelan SPJ, et al. Replication-competent vesicular stomatitis virus vaccine vector protects against SARS-CoV-2-mediated pathogenesis. Biorxiv : the Preprint Server For Biology. PMID 32676597 DOI: 10.1101/2020.07.09.196386  0.456
2020 Zost SJ, Gilchuk P, Chen RE, Case JB, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Chen EC, Binshtein E, Shrihari S, Ostrowski M, Chu HY, Didier JE, ... ... Rothlauf PW, et al. Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein. Nature Medicine. PMID 32651581 DOI: 10.1038/S41591-020-0998-X  0.404
2020 Case JB, Rothlauf PW, Chen RE, Liu Z, Zhao H, Kim AS, Bloyet LM, Zeng Q, Tahan S, Droit L, Ilagan MXG, Tartell MA, Amarasinghe G, Henderson JP, Miersch S, et al. Neutralizing antibody and soluble ACE2 inhibition of a replication-competent VSV-SARS-CoV-2 and a clinical isolate of SARS-CoV-2. Biorxiv : the Preprint Server For Biology. PMID 32511401 DOI: 10.1101/2020.05.18.102038  0.369
2020 Kang YL, Chou YY, Rothlauf PW, Liu Z, Soh TK, Cureton D, Case JB, Chen RE, Diamond MS, Whelan SPJ, Kirchhausen T. Inhibition of PIKfyve kinase prevents infection by EBOV and SARS-CoV-2. Biorxiv : the Preprint Server For Biology. PMID 32511398 DOI: 10.1101/2020.04.21.053058  0.515
2020 Zang R, Gomez Castro MF, McCune BT, Zeng Q, Rothlauf PW, Sonnek NM, Liu Z, Brulois KF, Wang X, Greenberg HB, Diamond MS, Ciorba MA, Whelan SPJ, Ding S. TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes. Science Immunology. 5. PMID 32404436 DOI: 10.1126/Sciimmunol.Abc3582  0.474
2019 Zuo Y, Whitbeck JC, Haila GJ, Hakim AA, Rothlauf PW, Eisenberg RJ, Cohen GH, Krummenacher C. Saliva enhances infection of gingival fibroblasts by herpes simplex virus 1. Plos One. 14: e0223299. PMID 31581238 DOI: 10.1371/Journal.Pone.0223299  0.525
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