| Year |
Citation |
Score |
| 2023 |
Sinclair F, Begum AA, Dai CC, Toth I, Moyle PM. Recent advances in the delivery and applications of nonviral CRISPR/Cas9 gene editing. Drug Delivery and Translational Research. 13: 1500-1519. PMID 36988873 DOI: 10.1007/s13346-023-01320-z |
0.727 |
|
| 2023 |
Yang J, Boer JC, Khongkow M, Phunpee S, Khalil ZG, Bashiri S, Deceneux C, Goodchild G, Hussein WM, Capon RJ, Ruktanonchai U, Plebanski M, Toth I, Skwarczynski M. The Development of Surface-Modified Liposomes as an Intranasal Delivery System for Group A Streptococcus Vaccines. Vaccines. 11. PMID 36851183 DOI: 10.3390/vaccines11020305 |
0.525 |
|
| 2023 |
Firdaus FZ, Bartlett S, Hussein WM, Lu L, Wright Q, Huang W, Nahar UJ, Yang J, Khongkow M, Veitch M, Koirala P, Ruktanonchai UR, Monteiro MJ, Gonzalez Cruz JL, Stephenson RJ, ... ... Toth I, et al. Liposomal Formulations of a Polyleucine-Antigen Conjugate as Therapeutic Vaccines against Cervical Cancer. Pharmaceutics. 15. PMID 36839923 DOI: 10.3390/pharmaceutics15020602 |
0.532 |
|
| 2022 |
Kiong J, Nahar UJ, Jin S, Shalash AO, Zhang J, Koirala P, Khalil ZG, Capon RJ, Skwarczynski M, Toth I, Hussein WM. Development of Multilayer Nanoparticles for the Delivery of Peptide-Based Subunit Vaccine against Group A . Pharmaceutics. 14. PMID 36297584 DOI: 10.3390/pharmaceutics14102151 |
0.508 |
|
| 2022 |
Azuar A, Madge HYR, Boer JC, Gonzalez Cruz JL, Wang J, Khalil ZG, Deceneux C, Goodchild G, Yang J, Koirala P, Hussein WM, Capon RJ, Plebanski M, Toth I, Skwarczynski M. Poly(hydrophobic Amino Acids) and Liposomes for Delivery of Vaccine against Group A Streptococcus. Vaccines. 10. PMID 36016100 DOI: 10.3390/vaccines10081212 |
0.525 |
|
| 2022 |
Shalash AO, Azuar A, Madge HYR, Modhiran N, Amarilla AA, Liang B, Khromykh AA, Hussein WM, Chappell KJ, Watterson D, Young PR, Skwarczynski M, Toth I. Peptide-Based Vaccine against SARS-CoV-2: Peptide Antigen Discovery and Screening of Adjuvant Systems. Pharmaceutics. 14. PMID 35456690 DOI: 10.3390/pharmaceutics14040856 |
0.546 |
|
| 2022 |
Shalash AO, Becker L, Yang J, Giacomin P, Pearson M, Hussein WM, Loukas A, Toth I, Skwarczynski M. Development of a Peptide Vaccine against Hookworm Infection: Immunogenicity, Efficacy, and Immune Correlates of Protection. The Journal of Allergy and Clinical Immunology. PMID 35278494 DOI: 10.1016/j.jaci.2022.02.020 |
0.522 |
|
| 2022 |
Islam MT, Ho MF, Nahar UJ, Shalash AO, Koirala P, Hussein WM, Stanisic DI, Good MF, Skwarczynski M, Toth I. Investigation of liposomal self-adjuvanting peptide epitopes derived from conserved blood-stage Plasmodium antigens. Plos One. 17: e0264961. PMID 35275957 DOI: 10.1371/journal.pone.0264961 |
0.455 |
|
| 2022 |
Huang W, Madge HYR, Zhang J, Gilmartin L, Hussein WM, Khalil ZG, Koirala P, Capon RJ, Toth I, Stephenson RJ. Structure-activity relationship of lipid, cyclic peptide and antigen rearrangement of physically mixed vaccines. International Journal of Pharmaceutics. 617: 121614. PMID 35245637 DOI: 10.1016/j.ijpharm.2022.121614 |
0.518 |
|
| 2022 |
Zhao L, Bashiri S, Toth I, Skwarczynski M. Preparation of Trimethyl Chitosan-Based Polyelectrolyte Complexes for Peptide Subunit Vaccine Delivery. Methods in Molecular Biology (Clifton, N.J.). 2414: 141-149. PMID 34784036 DOI: 10.1007/978-1-0716-1900-1_9 |
0.529 |
|
| 2021 |
Madge HYR, Huang W, Gilmartin L, Rigau-Planella B, Hussein WM, Khalil ZG, Koirala P, Santiago VS, Capon RJ, Toth I, Stephenson RJ. Physical mixture of a cyclic lipopeptide vaccine induced high titres of opsonic IgG antibodies against group A streptococcus. Biomaterials Science. PMID 34853841 DOI: 10.1039/d1bm01333e |
0.473 |
|
| 2021 |
Stanisic DI, Ho MF, Nevagi R, Cooper E, Walton M, Islam MT, Hussein WM, Skwarczynski M, Toth I, Good MF. Development and Evaluation of a Cryopreserved Whole-Parasite Vaccine in a Rodent Model of Blood-Stage Malaria. Mbio. 12: e0265721. PMID 34663097 DOI: 10.1128/mBio.02657-21 |
0.368 |
|
| 2021 |
Shalash AO, Becker L, Yang J, Giacomin P, Pearson M, Hussein WM, Loukas A, Skwarczynski M, Toth I. Oral Peptide Vaccine against Hookworm Infection: Correlation of Antibody Titers with Protective Efficacy. Vaccines. 9. PMID 34579271 DOI: 10.3390/vaccines9091034 |
0.53 |
|
| 2021 |
Azuar A, Shibu MA, Adilbish N, Marasini N, Hung H, Yang J, Luo Y, Khalil ZG, Capon RJ, Hussein WM, Toth I, Skwarczynski M. Poly(hydrophobic amino acid) Conjugates for the Delivery of Multiepitope Vaccine against Group A Streptococcus. Bioconjugate Chemistry. PMID 34379392 DOI: 10.1021/acs.bioconjchem.1c00333 |
0.534 |
|
| 2021 |
Yang J, Firdaus F, Azuar A, Khalil ZG, Marasini N, Capon RJ, Hussein WM, Toth I, Skwarczynski M. Cell-Penetrating Peptides-Based Liposomal Delivery System Enhanced Immunogenicity of Peptide-Based Vaccine against Group A Streptococcus. Vaccines. 9. PMID 34066099 DOI: 10.3390/vaccines9050499 |
0.579 |
|
| 2021 |
Al-Nazal HA, Cooper E, Ho MF, Eskandari S, Majam V, Giddam AK, Hussein WM, Islam MT, Skwarczynski M, Toth I, Kumar S, Zaid A, Batzloff M, Stanisic DI, Good MF. Pre-clinical evaluation of a whole-parasite vaccine to control human babesiosis. Cell Host & Microbe. PMID 33989514 DOI: 10.1016/j.chom.2021.04.008 |
0.424 |
|
| 2021 |
Pandey M, Ozberk V, Eskandari S, Shalash AO, Joyce MA, Saffran HA, Day CJ, Lepletier A, Spillings BL, Mills JL, Calcutt A, Fan F, Williams JT, Stanisic DI, Hattingh L, ... ... Toth I, et al. Antibodies to neutralising epitopes synergistically block the interaction of the receptor-binding domain of SARS-CoV-2 to ACE 2. Clinical & Translational Immunology. 10: e1260. PMID 33732459 DOI: 10.1002/cti2.1260 |
0.384 |
|
| 2021 |
Dai CC, Huang W, Yang J, Hussein WM, Wang J, Khalil ZG, Capon RJ, Toth I, Stephenson RJ. Polyethylenimine quantity and molecular weight influence its adjuvanting properties in liposomal peptide vaccines. Bioorganic & Medicinal Chemistry Letters. 127920. PMID 33705898 DOI: 10.1016/j.bmcl.2021.127920 |
0.772 |
|
| 2021 |
Khatun F, Dai CC, Rivera-Hernandez T, Hussein WM, Khalil ZG, Capon RJ, Toth I, Stephenson RJ. Immunogenicity Assessment of Cell Wall Carbohydrates of Group A via Self-Adjuvanted Glyco-lipopeptides. Acs Infectious Diseases. PMID 33533246 DOI: 10.1021/acsinfecdis.0c00722 |
0.776 |
|
| 2021 |
Azuar A, Li Z, Shibu MA, Zhao L, Luo Y, Shalash AO, Khalil ZG, Capon RJ, Hussein WM, Toth I, Skwarczynski M. Poly(hydrophobic amino acid)-Based Self-Adjuvanting Nanoparticles for Group A Vaccine Delivery. Journal of Medicinal Chemistry. PMID 33529034 DOI: 10.1021/acs.jmedchem.0c01660 |
0.535 |
|
| 2020 |
Rivera-Hernandez T, Carnathan DG, Jones S, Cork AJ, Davies MR, Moyle PM, Toth I, Batzloff MR, McCarthy J, Nizet V, Goldblatt D, Silvestri G, Walker MJ. Erratum for Rivera-Hernandez et al., "An Experimental Group A Vaccine That Reduces Pharyngitis and Tonsillitis in a Nonhuman Primate Model". Mbio. 11. PMID 33262263 DOI: 10.1128/mBio.02995-20 |
0.556 |
|
| 2020 |
Zhao L, Yang J, Nahar UJ, Khalil ZG, Capon RJ, Hussein WM, Skwarczynski M, Toth I. A dual-adjuvanting strategy for peptide-based subunit vaccines against group A Streptococcus: Lipidation and polyelectrolyte complexes. Bioorganic & Medicinal Chemistry. 28: 115823. PMID 33120079 DOI: 10.1016/j.bmc.2020.115823 |
0.437 |
|
| 2020 |
Dai CC, Yang J, Hussein WM, Zhao L, Wang X, Khalil ZG, Capon RJ, Toth I, Stephenson RJ. Polyethylenimine: An Intranasal Adjuvant for Liposomal Peptide-Based Subunit Vaccine against Group A . Acs Infectious Diseases. PMID 32786276 DOI: 10.1021/Acsinfecdis.0C00452 |
0.783 |
|
| 2020 |
Skwarczynski M, Chandrudu S, Rigau-Planella B, Islam MT, Cheong YS, Liu G, Wang X, Toth I, Hussein WM. Progress in the Development of Subunit Vaccines against Malaria. Vaccines. 8. PMID 32664421 DOI: 10.3390/vaccines8030373 |
0.497 |
|
| 2020 |
Dai C, Khalil ZG, Hussein WM, Yang J, Wang X, Zhao L, Capon RJ, Toth I, Stephenson RJ. Opsonic Activity of Conservative Versus Variable Regions of the Group A M Protein. Vaccines. 8. PMID 32392777 DOI: 10.3390/Vaccines8020210 |
0.422 |
|
| 2020 |
Zhao L, Jin W, Cruz JG, Marasini N, Khalil ZG, Capon RJ, Hussein WM, Skwarczynski M, Toth I. Development of Polyelectrolyte Complexes for the Delivery of Peptide-Based Subunit Vaccines against Group A . Nanomaterials (Basel, Switzerland). 10. PMID 32357402 DOI: 10.3390/Nano10050823 |
0.542 |
|
| 2020 |
Madge HYR, Sharma H, Hussein WM, Khalil ZG, Capon RJ, Toth I, Stephenson R. Structure-Activity Analysis of Cyclic Multicomponent Lipopeptide Self-Adjuvanting Vaccine Candidates Presenting Group A Streptococcus Antigens. Journal of Medicinal Chemistry. PMID 32347723 DOI: 10.1021/Acs.Jmedchem.0C00203 |
0.507 |
|
| 2020 |
Skwarczynski M, Zhao G, Boer JC, Ozberk V, Azuar A, Cruz JG, Giddam AK, Khalil ZG, Pandey M, Shibu MA, Hussein WM, Nevagi RJ, Batzloff MR, Wells JW, Capon RJ, ... ... Toth I, et al. Poly(amino acids) as a potent self-adjuvanting delivery system for peptide-based nanovaccines. Science Advances. 6: eaax2285. PMID 32064333 DOI: 10.1126/Sciadv.Aax2285 |
0.485 |
|
| 2020 |
Faruck MO, Zhao L, Hussein WM, Khalil ZG, Capon RJ, Skwarczynski M, Toth I. Polyacrylate-Peptide Antigen Conjugate as a Single-Dose Oral Vaccine against Group A . Vaccines. 8. PMID 31941060 DOI: 10.3390/Vaccines8010023 |
0.468 |
|
| 2019 |
Zhao L, Skwarczynski M, Toth I. Polyelectrolyte-Based Platforms for the Delivery of Peptides and Proteins. Acs Biomaterials Science & Engineering. 5: 4937-4950. PMID 33455241 DOI: 10.1021/acsbiomaterials.9b01135 |
0.413 |
|
| 2019 |
Ssemaganda A, Giddam AK, Low LM, Liu XQ, Ho MF, Zaman M, Hussein WM, Skwarczynski M, Toth I, Stanisic DI, Good MF. Mannosylated liposomes formulated with whole parasite P. falciparum blood-stage antigens are highly immunogenic in mice. Vaccine. PMID 31866187 DOI: 10.1016/j.vaccine.2019.11.063 |
0.415 |
|
| 2019 |
Bartlett S, Eichenberger RM, Nevagi RJ, Ghaffar KA, Marasini N, Dai Y, Loukas A, Toth I, Skwarczynski M. Lipopeptide-based oral vaccine against hookworm infection. The Journal of Infectious Diseases. PMID 31621864 DOI: 10.1093/infdis/jiz528 |
0.466 |
|
| 2019 |
Azuar A, Zhao L, Hei TT, Nevagi RJ, Bartlett S, Hussein WM, Khalil ZG, Capon RJ, Toth I, Skwarczynski M. Cholic Acid-based Delivery System for Vaccine Candidates against Group A Streptococcus. Acs Medicinal Chemistry Letters. 10: 1253-1259. PMID 31531193 DOI: 10.1021/Acsmedchemlett.9B00239 |
0.544 |
|
| 2019 |
Hussein W, Cheong Y, Liu C, Liu G, Begum A, Attallah MA, Moyle PM, Torchilin V, Smith R, Toth I. Peptide-based targeted polymeric nanoparticles for siRNA delivery. Nanotechnology. PMID 31295734 DOI: 10.1088/1361-6528/Ab313D |
0.555 |
|
| 2019 |
Nevagi RJ, Dai W, Khalil ZG, Hussein WM, Capon RJ, Skwarczynski M, Toth I. Structure-activity relationship of group A streptococcus lipopeptide vaccine candidates in trimethyl chitosan-based self-adjuvanting delivery system. European Journal of Medicinal Chemistry. 179: 100-108. PMID 31247372 DOI: 10.1016/J.Ejmech.2019.06.047 |
0.496 |
|
| 2019 |
Nevagi RJ, Dai W, Khalil ZG, Hussein WM, Capon RJ, Skwarczynski M, Toth I. Self-assembly of trimethyl chitosan and poly(anionic amino acid)-peptide antigen conjugate to produce a potent self-adjuvanting nanovaccine delivery system. Bioorganic & Medicinal Chemistry. PMID 31176567 DOI: 10.1016/J.Bmc.2019.05.033 |
0.454 |
|
| 2019 |
Ara Beguma A, Toth I, Hussein WM, Moyle PM. Advances in targeted gene delivery. Current Drug Delivery. PMID 31142250 DOI: 10.2174/1567201816666190529072914 |
0.517 |
|
| 2019 |
Begum AA, Toth I, Moyle PM. Gastrin-releasing peptide receptor-targeted hybrid peptide/phospholipid pDNA/siRNA delivery systems. Nanomedicine (London, England). PMID 31050581 DOI: 10.2217/nnm-2018-0380 |
0.582 |
|
| 2019 |
Rivera-Hernandez T, Carnathan DG, Jones S, Cork AJ, Davies MR, Moyle PM, Toth I, Batzloff MR, McCarthy J, Nizet V, Goldblatt D, Silvestri G, Walker MJ. An Experimental Group A Vaccine That Reduces Pharyngitis and Tonsillitis in a Nonhuman Primate Model. Mbio. 10. PMID 31040243 DOI: 10.1128/Mbio.00693-19 |
0.641 |
|
| 2019 |
Ssemaganda A, Giddam AK, Zaman M, Skwarczynski M, Toth I, Stanisic DI, Good MF. Induction of Plasmodium-Specific Immune Responses Using Liposome-Based Vaccines. Frontiers in Immunology. 10: 135. PMID 30774635 DOI: 10.3389/fimmu.2019.00135 |
0.479 |
|
| 2018 |
Bartlett S, Skwarczynski M, Toth I. Lipids as activators of innate immunity in peptide vaccine delivery. Current Medicinal Chemistry. PMID 30362416 DOI: 10.2174/0929867325666181026100849 |
0.482 |
|
| 2018 |
Nevagi RJ, Khalil ZG, Hussein WM, Powell J, Batzloff MR, Capon RJ, Good MF, Skwarczynski M, Toth I. Polyglutamic acid-trimethyl chitosan-based intranasal peptide nano-vaccine induces potent immune responses against group A streptococcus. Acta Biomaterialia. PMID 30266637 DOI: 10.1016/J.Actbio.2018.09.037 |
0.513 |
|
| 2018 |
Eskandari S, Pattinson D, Stephenson R, Groves P, Apte S, Sedaghat B, Chandurudu S, Doolan D, Toth I. The Influence of Physicochemical Properties of Lipopeptide Adjuvants on Immune Response: A Rationale for Engineering a Potent Vaccine. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29707835 DOI: 10.1002/chem.201801378 |
0.422 |
|
| 2017 |
Begum AA, Wan Y, Toth I, Moyle PM. Bombesin/oligoarginine fusion peptides for gastrin releasing peptide receptor (GRPR) targeted gene delivery. Bioorganic & Medicinal Chemistry. PMID 29269254 DOI: 10.1016/j.bmc.2017.12.013 |
0.588 |
|
| 2017 |
Jaberolansar N, Chappell KJ, Watterson D, Bermingham IM, Toth I, Young PR, Skwarczynski M. Induction of high titred, non-neutralising antibodies by self-adjuvanting peptide epitopes derived from the respiratory syncytial virus fusion protein. Scientific Reports. 7: 11130. PMID 28894111 DOI: 10.1038/S41598-017-10415-W |
0.424 |
|
| 2017 |
Wan Y, Dai W, J Nevagi R, Toth I, Moyle PM. Multifunctional peptide-lipid nanocomplexes for efficient targeted delivery of DNA and siRNA into breast cancer cells. Acta Biomaterialia. PMID 28655658 DOI: 10.1016/j.actbio.2017.06.032 |
0.568 |
|
| 2017 |
Khatun F, Stephenson RJ, Toth I. Corrigendum: An Overview of Structural Features of Antibacterial Glycoconjugate Vaccines That Influence Their Immunogenicity. Chemistry (Weinheim An Der Bergstrasse, Germany). 23: 6458. PMID 28480633 DOI: 10.1002/chem.201701478 |
0.407 |
|
| 2017 |
Hussein WM, Mukaida S, Azmi F, Bartlett S, Olivier C, Batzloff MR, Good MF, Skwarczynski M, Toth I. Comparison of Fluorinated and Nonfluorinated Lipids in Self-Adjuvanting Delivery Systems for Peptide-Based Vaccines. Acs Medicinal Chemistry Letters. 8: 227-232. PMID 28197317 DOI: 10.1021/acsmedchemlett.6b00453 |
0.556 |
|
| 2017 |
Wan Y, Moyle PM, Gn PZ, Toth I. Design and evaluation of a stearylated multicomponent peptide-siRNA nanocomplex for efficient cellular siRNA delivery. Nanomedicine (London, England). PMID 28093948 DOI: 10.2217/nnm-2016-0354 |
0.575 |
|
| 2017 |
Fagan V, Hussein WM, Su M, Gidda AK, Batzloff MR, Good MF, Toth I, Simerska P. Synthesis, Characterization and Immunological Evaluation of Self-Adjuvanting Group A Streptococcal Vaccine Candidates Bearing Various Lipidic Adjuvanting Moieties. Chembiochem : a European Journal of Chemical Biology. PMID 28075053 DOI: 10.1002/cbic.201600639 |
0.461 |
|
| 2016 |
Hussein WM, Liu TY, Maruthayanar P, Mukaida S, Moyle PM, Wells JW, Toth I, Skwarczynski M. Double conjugation strategy to incorporate lipid adjuvants into multiantigenic vaccines. Chemical Science. 7: 2308-2321. PMID 29910921 DOI: 10.1039/c5sc03859f |
0.678 |
|
| 2016 |
Khatun F, Stephenson RJ, Toth I. An Overview of Structural Features of Antibacterial Glycoconjugate Vaccines That Influence Their Immunogenicity. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28097690 DOI: 10.1002/chem.201603599 |
0.472 |
|
| 2016 |
Zaman M, Ozberk V, Langshaw EL, McPhun V, Powell JL, Phillips ZN, Ho MF, Calcutt A, Batzloff MR, Toth I, Hill GR, Pandey M, Good MF. Novel platform technology for modular mucosal vaccine that protects against streptococcus. Scientific Reports. 6: 39274. PMID 27976706 DOI: 10.1038/srep39274 |
0.525 |
|
| 2016 |
Marasini N, Giddam AK, Khalil ZG, Hussein WM, Capon RJ, Batzloff MR, Good MF, Toth I, Skwarczynski M. Double adjuvanting strategy for peptide-based vaccines: trimethyl chitosan nanoparticles for lipopeptide delivery. Nanomedicine (London, England). PMID 27830630 DOI: 10.2217/Nnm-2016-0291 |
0.517 |
|
| 2016 |
Begum AA, Moyle PM, Toth I. Investigation of bombesin peptide as a targeting ligand for the gastrin releasing peptide (GRP) receptor. Bioorganic & Medicinal Chemistry. PMID 27670095 DOI: 10.1016/j.bmc.2016.09.039 |
0.542 |
|
| 2016 |
Marasini N, Khalil ZG, Giddam AK, Ghaffar KA, Hussein WM, Capon RJ, Batzloff MR, Good MF, Skwarczynski M, Toth I. Lipid core peptide/poly(lactic-co-glycolic acid) as a highly potent intranasal vaccine delivery system against Group A streptococcus. International Journal of Pharmaceutics. PMID 27659862 DOI: 10.1016/J.Ijpharm.2016.09.057 |
0.496 |
|
| 2016 |
Chandrudu S, Bartlett S, Khalil ZG, Jia Z, Hussein WM, Capon RJ, Batzloff MR, Good MF, Monteiro MJ, Skwarczynski M, Toth I. Linear and branched polyacrylates as a delivery platform for peptide-based vaccines. Therapeutic Delivery. 7: 601-9. PMID 27582233 DOI: 10.4155/Tde-2016-0037 |
0.547 |
|
| 2016 |
Giddam AK, Reiman JM, Zaman M, Skwarczynski M, Toth I, Good MF. A semi-synthetic whole parasite vaccine designed to protect against blood stage malaria. Acta Biomaterialia. PMID 27544810 DOI: 10.1016/J.Actbio.2016.08.020 |
0.456 |
|
| 2016 |
Hussein WM, Choi P, Zhang C, Su M, Sierecki E, Johnston W, Fagan V, Alexandrov K, Skwarczynski M, Gambin Y, Toth I, Simerska P. Evaluation of lipopeptides as toll-like receptor 2 ligands. Current Drug Delivery. PMID 27494158 DOI: 10.2174/1567201813666160804114107 |
0.433 |
|
| 2016 |
Hussein WM, Liu TY, Jia Z, McMillan NA, Monteiro MJ, Toth I, Skwarczynski M. Multiantigenic peptide-polymer conjugates as therapeutic vaccines against cervical cancer. Bioorganic & Medicinal Chemistry. PMID 27475535 DOI: 10.1016/j.bmc.2016.07.036 |
0.325 |
|
| 2016 |
Eskandari S, Guerin T, Toth I, Stephenson RJ. Recent advances in self-assembled peptides: Implications for targeted drug delivery and vaccine engineering. Advanced Drug Delivery Reviews. PMID 27356149 DOI: 10.1016/j.addr.2016.06.013 |
0.423 |
|
| 2016 |
Rivera-Hernandez T, Pandey M, Henningham A, Cole J, Choudhury B, Cork AJ, Gillen CM, Ghaffar KA, West NP, Silvestri G, Good MF, Moyle PM, Toth I, Nizet V, Batzloff MR, et al. Differing Efficacies of Lead Group A Streptococcal Vaccine Candidates and Full-Length M Protein in Cutaneous and Invasive Disease Models. Mbio. 7. PMID 27302756 DOI: 10.1128/Mbio.00618-16 |
0.667 |
|
| 2016 |
Chan A, Hussein WM, Ghaffar KA, Marasini N, Mostafa A, Eskandari S, Batzloff MR, Good MF, Skwarczynski M, Toth I. Structure-activity relationship of lipid core peptide-based Group A Streptococcus vaccine candidates. Bioorganic & Medicinal Chemistry. PMID 27246859 DOI: 10.1016/j.bmc.2016.03.063 |
0.522 |
|
| 2016 |
Marasini N, Giddam AK, Ghaffar KA, Batzloff MR, Good MF, Skwarczynski M, Toth I. Multilayer engineered nanoliposomes as a novel tool for oral delivery of lipopeptide-based vaccines against group A Streptococcus. Nanomedicine (London, England). 11: 1223-36. PMID 27077314 DOI: 10.2217/nnm.16.36 |
0.443 |
|
| 2016 |
Ghaffar KA, Marasini N, Giddam AK, Batzloff M, Good M, Skwarczynski M, Toth I. Liposome-based Intranasal Delivery of Lipopeptide Vaccine Candidates Against Group A Streptococcus. Acta Biomaterialia. PMID 27063491 DOI: 10.1016/j.actbio.2016.04.012 |
0.525 |
|
| 2016 |
Wan Y, Moyle PM, Christie MP, Toth I. Nanosized, peptide-based multicomponent DNA delivery systems: optimization of endosome escape activity. Nanomedicine (London, England). PMID 26979574 DOI: 10.2217/nnm.16.27 |
0.577 |
|
| 2016 |
Sedaghat B, Stephenson RJ, Giddam AK, Eskandari S, Apte SH, Pattinson DJ, Doolan DL, Toth I. Synthesis of Mannosylated Lipopeptides with Receptor Targeting Properties. Bioconjugate Chemistry. 27: 533-48. PMID 26735314 DOI: 10.1021/acs.bioconjchem.5b00547 |
0.453 |
|
| 2016 |
Jaberolansar N, Toth I, Young PR, Skwarczynski M. Recent advances in the development of subunit-based RSV vaccines. Expert Review of Vaccines. 15: 53-68. PMID 26506139 DOI: 10.1586/14760584.2016.1105134 |
0.437 |
|
| 2015 |
Apte SH, Stephenson RJ, Simerska P, Groves PL, Aljohani S, Eskandari S, Toth I, Doolan DL. Systematic evaluation of self-adjuvanting lipopeptide nano-vaccine platforms for the induction of potent CD8(+) T-cell responses. Nanomedicine (London, England). PMID 26653407 DOI: 10.2217/nnm.15.184 |
0.395 |
|
| 2015 |
Moyle PM, Dai W, Liu TY, Hussein WM, Maruthayanar P, Wells JW, McMillan NA, Skwarczynski M, Toth I. Combined synthetic and recombinant techniques for the development of lipoprotein-based, self-adjuvanting vaccines targeting human papillomavirus type-16 associated tumors. Bioorganic & Medicinal Chemistry Letters. 25: 5570-5. PMID 26514746 DOI: 10.1016/j.bmcl.2015.10.049 |
0.556 |
|
| 2015 |
Fuaad AA, Pearson MS, Pickering DA, Becker L, Zhao G, Loukas AC, Skwarczynski M, Toth I. Lipopeptide Nanoparticles: Development of Vaccines against Hookworm Parasite. Chemmedchem. PMID 26269385 DOI: 10.1002/cmdc.201500227 |
0.497 |
|
| 2015 |
Rosli N, Christie MP, Moyle PM, Toth I. Peptide based DNA nanocarriers incorporating a cell-penetrating peptide derived from neurturin protein and poly-L-lysine dendrons. Bioorganic & Medicinal Chemistry. 23: 2470-9. PMID 25882529 DOI: 10.1016/j.bmc.2015.03.058 |
0.571 |
|
| 2015 |
Ahmad Fuaad AA, Roubille R, Pearson MS, Pickering DA, Loukas AC, Skwarczynski M, Toth I. The use of a conformational cathepsin D-derived epitope for vaccine development against Schistosoma mansoni. Bioorganic & Medicinal Chemistry. 23: 1307-12. PMID 25684420 DOI: 10.1016/j.bmc.2015.01.033 |
0.523 |
|
| 2015 |
Liu TY, Hussein WM, Giddam AK, Jia Z, Reiman JM, Zaman M, McMillan NA, Good MF, Monteiro MJ, Toth I, Skwarczynski M. Polyacrylate-based delivery system for self-adjuvanting anticancer peptide vaccine. Journal of Medicinal Chemistry. 58: 888-96. PMID 25489968 DOI: 10.1021/Jm501514H |
0.525 |
|
| 2015 |
Eskandari S, Stephenson RJ, Fuaad AA, Apte SH, Doolan DL, Toth I. Synthesis and characterisation of self-assembled and self-adjuvanting asymmetric multi-epitope lipopeptides of ovalbumin. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 1251-61. PMID 25399845 DOI: 10.1002/chem.201404997 |
0.419 |
|
| 2015 |
Liu TY, Giddam AK, Hussein WM, Jia Z, McMillan NA, Monteiro MJ, Toth I, Skwarczynski M. Self-adjuvanting therapeutic peptide-based vaccine induce CD8+ cytotoxic T lymphocyte responses in a murine human papillomavirus tumor model. Current Drug Delivery. 12: 3-8. PMID 25269453 |
0.385 |
|
| 2014 |
Stephenson R, You H, McManus DP, Toth I. Schistosome Vaccine Adjuvants in Preclinical and Clinical Research. Vaccines. 2: 654-85. PMID 26344751 DOI: 10.3390/vaccines2030654 |
0.468 |
|
| 2014 |
Rivera-Hernandez T, Carnathan DG, Moyle PM, Toth I, West NP, Young PR, Silvestri G, Walker MJ. The contribution of non-human primate models to the development of human vaccines. Discovery Medicine. 18: 313-22. PMID 25549702 |
0.583 |
|
| 2014 |
Zaman M, Chandrudu S, Giddam AK, Reiman J, Skwarczynski M, McPhun V, Moyle PM, Batzloff MR, Good MF, Toth I. Group A Streptococcal vaccine candidate: contribution of epitope to size, antigen presenting cell interaction and immunogenicity. Nanomedicine (London, England). 9: 2613-24. PMID 25529566 DOI: 10.2217/Nnm.14.190 |
0.671 |
|
| 2014 |
Azmi F, Ahmad Fuaad AA, Giddam AK, Batzloff MR, Good MF, Skwarczynski M, Toth I. Self-adjuvanting vaccine against group A streptococcus: application of fibrillized peptide and immunostimulatory lipid as adjuvant. Bioorganic & Medicinal Chemistry. 22: 6401-8. PMID 25438764 DOI: 10.1016/j.bmc.2014.09.042 |
0.526 |
|
| 2014 |
Goodwin D, Simerska P, Chang CH, Mansfeld FM, Varamini P, D'Occhio MJ, Toth I. Active immunisation of mice with GnRH lipopeptide vaccine candidates: Importance of T helper or multi-dimer GnRH epitope. Bioorganic & Medicinal Chemistry. 22: 4848-54. PMID 25059504 DOI: 10.1016/j.bmc.2014.06.052 |
0.382 |
|
| 2014 |
Moyle PM, Dai W, Zhang Y, Batzloff MR, Good MF, Toth I. Site-specific incorporation of three toll-like receptor 2 targeting adjuvants into semisynthetic, molecularly defined nanoparticles: application to group a streptococcal vaccines. Bioconjugate Chemistry. 25: 965-78. PMID 24712905 DOI: 10.1021/bc500108b |
0.69 |
|
| 2014 |
Ghaffar KA, Giddam AK, Zaman M, Skwarczynski M, Toth I. Liposomes as nanovaccine delivery systems. Current Topics in Medicinal Chemistry. 14: 1194-208. PMID 24678703 |
0.437 |
|
| 2014 |
Azmi F, Ahmad Fuaad AA, Skwarczynski M, Toth I. Recent progress in adjuvant discovery for peptide-based subunit vaccines. Human Vaccines & Immunotherapeutics. 10: 778-96. PMID 24300669 |
0.513 |
|
| 2014 |
Dougall AM, Skwarczynski M, Khoshnejad M, Chandrudu S, Daly NL, Toth I, Loukas A. Lipid core peptide targeting the cathepsin D hemoglobinase of Schistosoma mansoni as a component of a schistosomiasis vaccine. Human Vaccines & Immunotherapeutics. 10: 399-409. PMID 24231271 DOI: 10.4161/hv.27057 |
0.536 |
|
| 2014 |
Ahmad Fuaad AA, Jia Z, Zaman M, Hartas J, Ziora ZM, Lin IC, Moyle PM, Batzloff MR, Good MF, Monteiro MJ, Skwarczynski M, Toth I. Polymer-peptide hybrids as a highly immunogenic single-dose nanovaccine. Nanomedicine (London, England). 9: 35-43. PMID 23611619 DOI: 10.2217/nnm.13.7 |
0.592 |
|
| 2013 |
Ahmad Fuaad AAH, Azmi F, Skwarczynski M, Toth I. Peptide conjugation via CuAAC 'click' chemistry Molecules. 18: 13148-13174. PMID 24284482 DOI: 10.3390/molecules181113148 |
0.303 |
|
| 2013 |
Zaman M, Toth I. Immunostimulation by synthetic lipopeptide-based vaccine candidates: structure-activity relationships. Frontiers in Immunology. 4: 318. PMID 24130558 DOI: 10.3389/fimmu.2013.00318 |
0.484 |
|
| 2013 |
Liu TY, Hussein WM, Jia Z, Ziora ZM, McMillan NA, Monteiro MJ, Toth I, Skwarczynski M. Self-adjuvanting polymer-peptide conjugates as therapeutic vaccine candidates against cervical cancer. Biomacromolecules. 14: 2798-806. PMID 23837675 DOI: 10.1021/bm400626w |
0.431 |
|
| 2013 |
Zaman M, Good MF, Toth I. Nanovaccines and their mode of action. Methods (San Diego, Calif.). 60: 226-31. PMID 23623821 DOI: 10.1016/j.ymeth.2013.04.014 |
0.432 |
|
| 2013 |
Moyle PM, Hartas J, Henningham A, Batzloff MR, Good MF, Toth I. An efficient, chemically-defined semisynthetic lipid-adjuvanted nanoparticulate vaccine development system. Nanomedicine : Nanotechnology, Biology, and Medicine. 9: 935-44. PMID 23428988 DOI: 10.1016/j.nano.2013.01.009 |
0.643 |
|
| 2013 |
Moyle PM, Toth I. Modern subunit vaccines: development, components, and research opportunities. Chemmedchem. 8: 360-76. PMID 23316023 DOI: 10.1002/cmdc.201200487 |
0.656 |
|
| 2013 |
Giddam AK, Zaman M, Skwarczynski M, Toth I. Liposome-based delivery system for vaccine candidates: constructing an effective formulation. Nanomedicine (London, England). 7: 1877-93. PMID 23249332 DOI: 10.2217/nnm.12.157 |
0.461 |
|
| 2013 |
Skwarczynski M, Kamaruzaman KA, Srinivasan S, Zaman M, Lin IC, Batzloff MR, Good MF, Toth I. M-protein-derived conformational peptide epitope vaccine candidate against Group A Streptococcus. Current Drug Delivery. 10: 39-45. PMID 22998043 DOI: 10.2174/1567201811310010007 |
0.471 |
|
| 2012 |
Zaman M, Chandrudu S, Toth I. Strategies for intranasal delivery of vaccines. Drug Delivery and Translational Research. 3: 100-9. PMID 23316448 DOI: 10.1007/s13346-012-0085-z |
0.467 |
|
| 2012 |
Skwarczynski M, Dougall AM, Khoshnejad M, Chandrudu S, Pearson MS, Loukas A, Toth I. Peptide-based subunit vaccine against hookworm infection. Plos One. 7: e46870. PMID 23056500 DOI: 10.1371/journal.pone.0046870 |
0.445 |
|
| 2012 |
Zaman M, Abdel-Aal AB, Fujita Y, Ziora ZM, Batzloff MR, Good MF, Toth I. Structure-activity relationship for the development of a self-adjuvanting mucosally active lipopeptide vaccine against Streptococcus pyogenes. Journal of Medicinal Chemistry. 55: 8515-23. PMID 22974133 DOI: 10.1021/jm301074n |
0.466 |
|
| 2012 |
Apte SH, Groves PL, Skwarczynski M, Fujita Y, Chang C, Toth I, Doolan DL. Vaccination with lipid core peptides fails to induce epitope-specific T cell responses but confers non-specific protective immunity in a malaria model. Plos One. 7: e40928. PMID 22936972 DOI: 10.1371/journal.pone.0040928 |
0.459 |
|
| 2012 |
Liu TY, Hussein WM, Toth I, Skwarczynski M. Advances in peptide-based human papillomavirus therapeutic vaccines. Current Topics in Medicinal Chemistry. 12: 1581-92. PMID 22827526 |
0.365 |
|
| 2012 |
Abdel-Aal AB, El-Naggar D, Zaman M, Batzloff M, Toth I. Design of fully synthetic, self-adjuvanting vaccine incorporating the tumor-associated carbohydrate Tn antigen and lipoamino acid-based Toll-like receptor 2 ligand. Journal of Medicinal Chemistry. 55: 6968-74. PMID 22800462 DOI: 10.1021/jm300822g |
0.484 |
|
| 2012 |
Zaman M, Abdel-Aal AB, Fujita Y, Phillipps KS, Batzloff MR, Good MF, Toth I. Immunological evaluation of lipopeptide group A streptococcus (GAS) vaccine: structure-activity relationship. Plos One. 7: e30146. PMID 22253911 DOI: 10.1371/journal.pone.0030146 |
0.525 |
|
| 2011 |
Benson H, Toth I. The Eighth Australian Peptide Conference: peptides--tools, targets and therapeutics. Biopolymers. 96: iii. PMID 21714158 DOI: 10.1002/bip.21610 |
0.31 |
|
| 2011 |
Zaman M, Skwarczynski M, Malcolm JM, Urbani CN, Jia Z, Batzloff MR, Good MF, Monteiro MJ, Toth I. Self-adjuvanting polyacrylic nanoparticulate delivery system for group A streptococcus (GAS) vaccine. Nanomedicine : Nanotechnology, Biology, and Medicine. 7: 168-73. PMID 21034860 DOI: 10.1016/j.nano.2010.10.002 |
0.546 |
|
| 2011 |
Simerska P, Moyle PM, Toth I. Modern lipid-, carbohydrate-, and peptide-based delivery systems for peptide, vaccine, and gene products. Medicinal Research Reviews. 31: 520-47. PMID 20027671 DOI: 10.1002/med.20191 |
0.681 |
|
| 2010 |
Abdel-Aal AB, Zaman M, Fujita Y, Batzloff MR, Good MF, Toth I. Design of three-component vaccines against group A streptococcal infections: importance of spatial arrangement of vaccine components. Journal of Medicinal Chemistry. 53: 8041-6. PMID 21028828 DOI: 10.1021/jm1007787 |
0.434 |
|
| 2010 |
Skwarczynski M, Zaman M, Urbani CN, Lin IC, Jia Z, Batzloff MR, Good MF, Monteiro MJ, Toth I. Polyacrylate dendrimer nanoparticles: a self-adjuvanting vaccine delivery system. Angewandte Chemie (International Ed. in English). 49: 5742-5. PMID 20818757 DOI: 10.1002/anie.201002221 |
0.389 |
|
| 2010 |
Zaman M, Simerska P, Toth I. Synthetic polyacrylate polymers as particulate intranasal vaccine delivery systems for the induction of mucosal immune response. Current Drug Delivery. 7: 118-24. PMID 20158484 DOI: 10.2174/156720110791011846 |
0.434 |
|
| 2010 |
Zaman M, Abdel-Aal AM, Phillipps KSM, Fujita Y, Good MF, Toth I. Structure-activity relationship of lipopeptide Group A streptococcus (GAS) vaccine candidates on toll-like receptor 2. Vaccine. 28: 2243-2248. PMID 20045502 DOI: 10.1016/j.vaccine.2009.12.046 |
0.345 |
|
| 2010 |
Zhong W, Skwarczynski M, Toth I. Development of conformational mimetics of conserved Streptococcus pyogenes minimal epitope as vaccine candidates. Current Drug Delivery. 6: 520-7. PMID 19863488 DOI: 10.2174/156720109789941650 |
0.473 |
|
| 2009 |
Simerska P, Moyle PM, Olive C, Toth I. Oral vaccine delivery--new strategies and technologies. Current Drug Delivery. 6: 347-58. PMID 19534712 DOI: 10.2174/156720109789000537 |
0.677 |
|
| 2009 |
Toth I, Moyle PM, Simerska P, Fujita Y, Olive C, Good MF. Vaccine delivery: synthesis and investigation of a highly pure, multi-epitopic lipopeptide vaccine candidate. Advances in Experimental Medicine and Biology. 611: 347-9. PMID 19400221 DOI: 10.1007/978-0-387-73657-0_154 |
0.67 |
|
| 2009 |
Simerska P, McGeary RP, Abdel-Aal AB, Moyle PM, Olive C, Good MF, Toth I. Vaccine delivery utilizing liposaccharides. Advances in Experimental Medicine and Biology. 611: 345-6. PMID 19400220 DOI: 10.1007/978-0-387-73657-0_153 |
0.67 |
|
| 2008 |
Phillipps KS, Wykes MN, Liu XQ, Brown M, Blanchfield J, Toth I. A novel synthetic adjuvant enhances dendritic cell function. Immunology. 128: e582-8. PMID 19740319 DOI: 10.1111/j.1365-2567.2008.03038.x |
0.517 |
|
| 2008 |
Simerska P, Lu H, Toth I. Synthesis of a Streptococcus pyogenes vaccine candidate based on the M protein PL1 epitope. Bioorganic & Medicinal Chemistry Letters. 19: 821-4. PMID 19097790 DOI: 10.1016/j.bmcl.2008.12.013 |
0.494 |
|
| 2008 |
Fujita Y, Moyle PM, Hieu S, Simerska P, Toth I. Investigation toward multi-epitope vaccine candidates using native chemical ligation. Biopolymers. 90: 624-32. PMID 18979543 DOI: 10.1002/bip.21002 |
0.679 |
|
| 2008 |
Fujita Y, Abdel-Aal AB, Wimmer N, Batzloff MR, Good MF, Toth I. Synthesis and immunological evaluation of self-adjuvanting glycolipopeptide vaccine candidates. Bioorganic & Medicinal Chemistry. 16: 8907-13. PMID 18789866 DOI: 10.1016/j.bmc.2008.08.064 |
0.36 |
|
| 2008 |
Simerska P, Abdel-Aal AB, Fujita Y, Batzloff MR, Good MF, Toth I. Synthesis and in vivo studies of carbohydrate-based vaccines against group A streptococcus. Biopolymers. 90: 611-6. PMID 18381625 DOI: 10.1002/bip.20992 |
0.524 |
|
| 2008 |
Moyle PM, Toth I. Self-adjuvanting lipopeptide vaccines. Current Medicinal Chemistry. 15: 506-16. PMID 18289006 DOI: 10.2174/092986708783503249 |
0.705 |
|
| 2008 |
Simerska P, Abdel-Aal AB, Fujita Y, Moyle PM, McGeary RP, Batzloff MR, Olive C, Good MF, Toth I. Development of a liposaccharide-based delivery system and its application to the design of group A streptococcal vaccines. Journal of Medicinal Chemistry. 51: 1447-52. PMID 18278857 DOI: 10.1021/jm701410p |
0.694 |
|
| 2008 |
Abdel-Aal AB, Batzloff MR, Fujita Y, Barozzi N, Faria A, Simerska P, Moyle PM, Good MF, Toth I. Structure-activity relationship of a series of synthetic lipopeptide self-adjuvanting group a streptococcal vaccine candidates. Journal of Medicinal Chemistry. 51: 167-72. PMID 18072728 DOI: 10.1021/jm701091d |
0.637 |
|
| 2007 |
Moyle PM, Olive C, Ho MF, Pandey M, Dyer J, Suhrbier A, Fujita Y, Toth I. Toward the development of prophylactic and therapeutic human papillomavirus type-16 lipopeptide vaccines. Journal of Medicinal Chemistry. 50: 4721-7. PMID 17705361 DOI: 10.1021/jm070287b |
0.636 |
|
| 2007 |
Hayman WA, Toth I, Flinn N, Scanlon MJ, Good MF. Enhancing the immunogenicity and modulating the fine epitope recognition of antisera to A helical group a streptococcal peptide vaccine candidate from the M protein using lipid-core peptide technology Immunology and Cell Biology. 80: 178-187. PMID 11940119 DOI: 10.1046/j.1440-1711.2002.01067.x |
0.433 |
|
| 2006 |
Moyle PM, Olive C, Good MF, Toth I. Method for the synthesis of highly pure vaccines using the lipid core peptide system. Journal of Peptide Science : An Official Publication of the European Peptide Society. 12: 800-7. PMID 17131293 DOI: 10.1002/psc.815 |
0.708 |
|
| 2006 |
Liang MT, Davies NM, Blanchfield JT, Toth I. Particulate systems as adjuvants and carriers for peptide and protein antigens. Current Drug Delivery. 3: 379-88. PMID 17076640 DOI: 10.2174/156720106778559029 |
0.436 |
|
| 2006 |
Moyle PM, Olive C, Ho MF, Good MF, Toth I. Synthesis of a highly pure lipid core peptide based self-adjuvanting triepitopic group A streptococcal vaccine, and subsequent immunological evaluation. Journal of Medicinal Chemistry. 49: 6364-70. PMID 17034142 DOI: 10.1021/jm060475m |
0.714 |
|
| 2006 |
Moyle PM, Olive C, Ho MF, Burgess M, Karpati L, Good MF, Toth I. Method for the synthesis of multi-epitopic Streptococcus pyogenes lipopeptide vaccines using native chemical ligation. The Journal of Organic Chemistry. 71: 6846-50. PMID 16930036 DOI: 10.1021/jo060960p |
0.7 |
|
| 2006 |
Olive C, Sun HK, Ho MF, Dyer J, Horváth A, Toth I, Good MF. Intranasal administration is an effective mucosal vaccine delivery route for self-adjuvanting lipid core peptides targeting the group A streptococcal M protein Journal of Infectious Diseases. 194: 316-324. PMID 16826479 DOI: 10.1086/505580 |
0.535 |
|
| 2006 |
White K, Rades T, Kearns P, Toth I, Hook S. Immunogenicity of liposomes containing lipid core peptides and the adjuvant Quil A. Pharmaceutical Research. 23: 1473-81. PMID 16779706 DOI: 10.1007/s11095-006-0272-z |
0.371 |
|
| 2006 |
Olive C, Ho MF, Dyer J, Lincoln D, Barozzi N, Toth I, Good MF. Immunization with a tetraepitopic lipid core peptide vaccine construct induces broadly protective immune responses against group A streptococcus. The Journal of Infectious Diseases. 193: 1666-76. PMID 16703510 DOI: 10.1086/504266 |
0.449 |
|
| 2004 |
White K, Kearns P, Toth I, Hook S. Increased adjuvant activity of minimal CD8 T cell peptides incorporated into lipid-core-peptides. Immunology and Cell Biology. 82: 517-22. PMID 15479437 DOI: 10.1111/j.0818-9641.2004.01269.x |
0.434 |
|
| 2004 |
Horváth A, Olive C, Karpati L, Sun HK, Good M, Toth I. Toward the development of a synthetic group A streptococcal vaccine of high purity and broad protective coverage Journal of Medicinal Chemistry. 47: 4100-4104. PMID 15267249 DOI: 10.1021/jm040041w |
0.514 |
|
| 2002 |
Olive C, Batzloff MR, Horváth A, Wong A, Clair T, Yarwood P, Toth I, Good MF. A lipid core peptide construct containing a conserved region determinant of the group A streptococcal M protein elicits heterologous opsonic antibodies. Infection and Immunity. 70: 2734-8. PMID 11953422 DOI: 10.1128/IAI.70.5.2734-2738.2002 |
0.409 |
|
| 2002 |
Horvath A, Olive C, Wong A, Clair T, Yarwood P, Good M, Toth I. Lipoamino acid-based adjuvant carrier system: enhanced immunogenicity of group a streptococcal peptide epitopes. Journal of Medicinal Chemistry. 45: 1387-90. PMID 11882009 DOI: 10.1021/jm0110441 |
0.423 |
|
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