Qiang Zhao - Publications

Affiliations: 
2007-2011 Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, Shanghai Shi, China 

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Chen K, Zhang C, Lin S, Yan X, Cai H, Yi C, Ma L, Chu X, Liu Y, Zhu Y, Han S, Zhao Q, Wu B. Tail engagement of arrestin at the glucagon receptor. Nature. PMID 37558880 DOI: 10.1038/s41586-023-06420-x  0.685
2023 Xu G, Wang C, Yu H, Li Y, Zhao Q, Zhou X, Li C, Liu M. Structural basis for high-affinity recognition of aflatoxin B1 by a DNA aptamer. Nucleic Acids Research. PMID 37351632 DOI: 10.1093/nar/gkad541  0.339
2023 Wang X, Wang M, Xu T, Feng Y, Shao Q, Han S, Chu X, Xu Y, Lin S, Zhao Q, Wu B. Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers. Cell Research. PMID 37286794 DOI: 10.1038/s41422-023-00830-2  0.606
2023 Li B, Han S, Wang M, Yu Y, Ma L, Chu X, Tan Q, Zhao Q, Wu B. Structural insights into signal transduction of the purinergic receptors P2Y1R and P2Y12R. Protein & Cell. 14: 382-386. PMID 37155313 DOI: 10.1093/procel/pwac025  0.589
2022 Zang Y, Su M, Wang Q, Cheng X, Zhang W, Zhao Y, Chen T, Jiang Y, Shen Q, Du J, Tan Q, Wang P, Gao L, Jin Z, Zhang M, ... ... Zhao Q, et al. High-throughput screening of SARS-CoV-2 main and papain-like protease inhibitors. Protein & Cell. 14: 17-27. PMID 36726755 DOI: 10.1093/procel/pwac016  0.378
2022 Zhao W, Zhang W, Wang M, Lu M, Chen S, Tang T, Schnapp G, Wagner H, Brennauer A, Yi C, Chu X, Han S, Wu B, Zhao Q. Ligand recognition and activation of neuromedin U receptor 2. Nature Communications. 13: 7955. PMID 36575163 DOI: 10.1038/s41467-022-34814-4  0.64
2022 Wang L, Qie Y, Yang Y, Zhao Q. Binding and Activation of Estrogen-Related Receptor γ: A Novel Molecular Mechanism for the Estrogenic Disruption Effects of DDT and Its Metabolites. Environmental Science & Technology. PMID 35947429 DOI: 10.1021/acs.est.1c08624  0.405
2022 Lu M, Zhao W, Han S, Lin X, Xu T, Tan Q, Wang M, Yi C, Chu X, Yang W, Zhu Y, Wu B, Zhao Q. Activation of the human chemokine receptor CX3CR1 regulated by cholesterol. Science Advances. 8: eabn8048. PMID 35767622 DOI: 10.1126/sciadv.abn8048  0.663
2022 Zhao W, Han S, Qiu N, Feng W, Lu M, Zhang W, Wang M, Zhou Q, Chen S, Xu W, Du J, Chu X, Yi C, Dai A, Hu L, ... ... Zhao Q, et al. Structural insights into ligand recognition and selectivity of somatostatin receptors. Cell Research. PMID 35739238 DOI: 10.1038/s41422-022-00679-x  0.644
2022 Tang T, Tan Q, Han S, Diemar A, Löbner K, Wang H, Schüß C, Behr V, Mörl K, Wang M, Chu X, Yi C, Keller M, Kofoed J, Reedtz-Runge S, ... ... Zhao Q, et al. Receptor-specific recognition of NPY peptides revealed by structures of NPY receptors. Science Advances. 8: eabm1232. PMID 35507650 DOI: 10.1126/sciadv.abm1232  0.61
2022 Xu G, Zhao J, Yu H, Wang C, Huang Y, Zhao Q, Zhou X, Li C, Liu M. Structural Insights into the Mechanism of High-Affinity Binding of Ochratoxin A by a DNA Aptamer. Journal of the American Chemical Society. PMID 35442665 DOI: 10.1021/jacs.2c00478  0.33
2022 Qu X, Qiu N, Wang M, Zhang B, Du J, Zhong Z, Xu W, Chu X, Ma L, Yi C, Han S, Shui W, Zhao Q, Wu B. Structural basis of tethered agonism of the adhesion GPCRs ADGRD1 and ADGRF1. Nature. PMID 35418679 DOI: 10.1038/s41586-022-04580-w  0.634
2022 Zhu Y, Lin X, Zong X, Han S, Wang M, Su Y, Ma L, Chu X, Yi C, Zhao Q, Wu B. Structural basis of FPR2 in recognition of Aβ and neuroprotection by humanin. Nature Communications. 13: 1775. PMID 35365641 DOI: 10.1038/s41467-022-29361-x  0.546
2021 Zhao Q, Yuan JJ, Hu F, Qian C, Tian CF, Wang JT, Gao D, Yi W, Wang HB. Isolation, physicochemical, and structure-function relationship of the hydrophobic variant of Fc-fusion proteins that bind to TNF-α receptor, HS002 and HS002A. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1186: 123026. PMID 34781108 DOI: 10.1016/j.jchromb.2021.123026  0.319
2021 Zhang X, He C, Wang M, Zhou Q, Yang D, Zhu Y, Feng W, Zhang H, Dai A, Chu X, Wang J, Yang Z, Jiang Y, Sensfuss U, Tan Q, ... ... Zhao Q, et al. Structures of the human cholecystokinin receptors bound to agonists and antagonists. Nature Chemical Biology. PMID 34556863 DOI: 10.1038/s41589-021-00866-8  0.682
2021 Liu Q, Yang D, Zhuang Y, Croll TI, Cai X, Dai A, He X, Duan J, Yin W, Ye C, Zhou F, Wu B, Zhao Q, Xu HE, Wang MW, et al. Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor. Nature Chemical Biology. PMID 34556862 DOI: 10.1038/s41589-021-00841-3  0.582
2021 Zhang H, Chen K, Tan Q, Shao Q, Han S, Zhang C, Yi C, Chu X, Zhu Y, Xu Y, Zhao Q, Wu B. Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5. Nature Communications. 12: 4151. PMID 34230484 DOI: 10.1038/s41467-021-24438-5  0.745
2021 Zhang H, Chen K, Tan Q, Shao Q, Han S, Zhang C, Yi C, Chu X, Zhu Y, Xu Y, Zhao Q, Wu B. Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5. Nature Communications. 12: 4151. PMID 34230484 DOI: 10.1038/s41467-021-24438-5  0.745
2021 Lin S, Han S, Cai X, Tan Q, Zhou K, Wang D, Wang X, Du J, Yi C, Chu X, Dai A, Zhou Y, Chen Y, Zhou Y, Liu H, ... ... Zhao Q, et al. Structures of G-bound metabotropic glutamate receptors mGlu2 and mGlu4. Nature. PMID 34135510 DOI: 10.1038/s41586-021-03495-2  0.727
2021 Lin S, Han S, Cai X, Tan Q, Zhou K, Wang D, Wang X, Du J, Yi C, Chu X, Dai A, Zhou Y, Chen Y, Zhou Y, Liu H, ... ... Zhao Q, et al. Structures of G-bound metabotropic glutamate receptors mGlu2 and mGlu4. Nature. PMID 34135510 DOI: 10.1038/s41586-021-03495-2  0.727
2021 Du J, Wang D, Fan H, Xu C, Tai L, Lin S, Han S, Tan Q, Wang X, Xu T, Zhang H, Chu X, Yi C, Liu P, Wang X, ... ... Zhao Q, et al. Structures of human mGlu2 and mGlu7 homo- and heterodimers. Nature. PMID 34135509 DOI: 10.1038/s41586-021-03641-w  0.72
2021 Du J, Wang D, Fan H, Xu C, Tai L, Lin S, Han S, Tan Q, Wang X, Xu T, Zhang H, Chu X, Yi C, Liu P, Wang X, ... ... Zhao Q, et al. Structures of human mGlu2 and mGlu7 homo- and heterodimers. Nature. PMID 34135509 DOI: 10.1038/s41586-021-03641-w  0.72
2021 Tang T, Hartig C, Chen Q, Zhao W, Kaiser A, Zhang X, Zhang H, Qu H, Yi C, Ma L, Han S, Zhao Q, Beck-Sickinger AG, Wu B. Structural basis for ligand recognition of the neuropeptide Y Y receptor. Nature Communications. 12: 737. PMID 33531491 DOI: 10.1038/s41467-021-21030-9  0.679
2020 Ge YJ, Liao QW, Xu YC, Zhao Q, Wu BL, Ye RD. Anti-inflammatory signaling through G protein-coupled receptors. Acta Pharmacologica Sinica. PMID 33060777 DOI: 10.1038/s41401-020-00523-1  0.53
2020 Qiao A, Han S, Li X, Li Z, Zhao P, Dai A, Chang R, Tai L, Tan Q, Chu X, Ma L, Thorsen TS, Reedtz-Runge S, Yang D, Wang MW, ... ... Zhao Q, et al. Structural basis of G and G recognition by the human glucagon receptor. Science (New York, N.Y.). 367: 1346-1352. PMID 32193322 DOI: 10.1126/Science.Aaz5346  0.609
2020 Chen T, Xiong M, Zong X, Ge Y, Zhang H, Wang M, Won Han G, Yi C, Ma L, Ye RD, Xu Y, Zhao Q, Wu B. Structural basis of ligand binding modes at the human formyl peptide receptor 2. Nature Communications. 11: 1208. PMID 32139677 DOI: 10.1038/S41467-020-15009-1  0.676
2019 Chen S, Lu M, Liu D, Yang L, Yi C, Ma L, Zhang H, Liu Q, Frimurer TM, Wang MW, Schwartz TW, Stevens RC, Wu B, Wüthrich K, Zhao Q. Human substance P receptor binding mode of the antagonist drug aprepitant by NMR and crystallography. Nature Communications. 10: 638. PMID 30733446 DOI: 10.1038/S41467-019-08568-5  0.756
2018 Fan H, Chen S, Yuan X, Han S, Zhang H, Xia W, Xu Y, Zhao Q, Wu B. Structural basis for ligand recognition of the human thromboxane A receptor. Nature Chemical Biology. PMID 30510189 DOI: 10.1038/S41589-018-0170-9  0.713
2018 Baqi Y, Pillaiyar T, Abdelrahman A, Kaufmann O, Alshaibani S, Rafehi M, Ghasimi S, Akkari R, Ritter K, Simon K, Spinrath A, Kostenis E, Zhao Q, Köse M, Namasivayam V, et al. 3-(-2-Carboxyethyl)indole-2-carboxylic Acid Derivatives: Structural Requirements and Properties of Potent Agonists of the Orphan G Protein-Coupled Receptor GPR17. Journal of Medicinal Chemistry. PMID 30048589 DOI: 10.1021/Acs.Jmedchem.7B01768  0.425
2018 Zhu Y, Zhao YL, Li J, Liu H, Zhao Q, Wu BL, Yang ZL. Molecular binding mode of PF-232798, a clinical anti-HIV candidate, at chemokine receptor CCR5. Acta Pharmacologica Sinica. PMID 29941870 DOI: 10.1038/S41401-018-0054-2  0.597
2018 Cao C, Tan Q, Xu C, He L, Yang L, Zhou Y, Zhou Y, Qiao A, Lu M, Yi C, Han GW, Wang X, Li X, Yang H, Rao Z, ... ... Zhao Q, et al. Structural basis for signal recognition and transduction by platelet-activating-factor receptor. Nature Structural & Molecular Biology. PMID 29808000 DOI: 10.1038/S41594-018-0068-Y  0.73
2018 Yang Z, Han S, Keller M, Kaiser A, Bender BJ, Bosse M, Burkert K, Kögler LM, Wifling D, Bernhardt G, Plank N, Littmann T, Schmidt P, Yi C, Li B, ... ... Zhao Q, et al. Structural basis of ligand binding modes at the neuropeptide Y Y receptor. Nature. PMID 29670288 DOI: 10.1038/S41586-018-0046-X  0.759
2018 Zhang H, Qiao A, Yang L, Van Eps N, Frederiksen KS, Yang D, Dai A, Cai X, Zhang H, Yi C, Cao C, He L, Yang H, Lau J, Ernst OP, ... ... Zhao Q, et al. Structure of the glucagon receptor in complex with a glucagon analogue. Nature. 553: 106-110. PMID 29300013 DOI: 10.1038/Nature25153  0.757
2017 de Graaf C, Song G, Cao C, Zhao Q, Wang MW, Wu B, Stevens RC. Extending the Structural View of Class B GPCRs. Trends in Biochemical Sciences. PMID 29132948 DOI: 10.1016/J.Tibs.2017.10.003  0.753
2017 Zhang H, Qiao A, Yang D, Yang L, Dai A, de Graaf C, Reedtz-Runge S, Dharmarajan V, Zhang H, Han GW, Grant TD, Sierra RG, Weierstall U, Nelson G, Liu W, ... ... Zhao Q, et al. Structure of the full-length glucagon class B G-protein-coupled receptor. Nature. PMID 28514451 DOI: 10.1038/Nature22363  0.781
2016 Hua T, Vemuri K, Pu M, Qu L, Han GW, Wu Y, Zhao S, Shui W, Li S, Korde A, Laprairie RB, Stahl EL, Ho JH, Zvonok N, Zhou H, ... ... Zhao Q, et al. Crystal Structure of the Human Cannabinoid Receptor CB1. Cell. 167: 750-762.e14. PMID 27768894 DOI: 10.1016/J.Cell.2016.10.004  0.784
2015 Zhang D, Zhao Q, Wu B. Structural Studies of G Protein-Coupled Receptors. Molecules and Cells. PMID 26467290 DOI: 10.14348/molcells.2015.0263  0.636
2015 Paoletta S, Sabbadin D, von Kügelgen I, Hinz S, Katritch V, Hoffmann K, Abdelrahman A, Straßburger J, Baqi Y, Zhao Q, Stevens RC, Moro S, Müller CE, Jacobson KA. Modeling ligand recognition at the P2Y12 receptor in light of X-ray structural information. Journal of Computer-Aided Molecular Design. PMID 26194851 DOI: 10.1007/S10822-015-9858-Z  0.796
2015 Jacobson KA, Paoletta S, Katritch V, Wu B, Gao ZG, Zhao Q, Stevens RC, Kiselev E. Nucleotides Acting at P2Y Receptors: Connecting Structure and Function. Molecular Pharmacology. 88: 220-30. PMID 25837834 DOI: 10.1124/Mol.114.095711  0.802
2015 Zhang D, Gao ZG, Zhang K, Kiselev E, Crane S, Wang J, Paoletta S, Yi C, Ma L, Zhang W, Han GW, Liu H, Cherezov V, Katritch V, Jiang H, ... ... Zhao Q, et al. Two disparate ligand-binding sites in the human P2Y1 receptor. Nature. 520: 317-21. PMID 25822790 DOI: 10.1038/Nature14287  0.801
2014 Kiselev E, Barrett MO, Katritch V, Paoletta S, Weitzer CD, Brown KA, Hammes E, Yin AL, Zhao Q, Stevens RC, Harden TK, Jacobson KA. Exploring a 2-naphthoic acid template for the structure-based design of P2Y14 receptor antagonist molecular probes. Acs Chemical Biology. 9: 2833-42. PMID 25299434 DOI: 10.1021/Cb500614P  0.765
2014 Zhang J, Zhang K, Gao ZG, Paoletta S, Zhang D, Han GW, Li T, Ma L, Zhang W, Müller CE, Yang H, Jiang H, Cherezov V, Katritch V, Jacobson KA, ... ... Zhao Q, et al. Agonist-bound structure of the human P2Y12 receptor. Nature. 509: 119-22. PMID 24784220 DOI: 10.1038/Nature13288  0.813
2014 Zhang K, Zhang J, Gao ZG, Zhang D, Zhu L, Han GW, Moss SM, Paoletta S, Kiselev E, Lu W, Fenalti G, Zhang W, Müller CE, Yang H, Jiang H, ... ... Zhao Q, et al. Structure of the human P2Y12 receptor in complex with an antithrombotic drug. Nature. 509: 115-8. PMID 24670650 DOI: 10.1038/Nature13083  0.816
2013 Tan Q, Zhu Y, Li J, Chen Z, Han GW, Kufareva I, Li T, Ma L, Fenalti G, Li J, Zhang W, Xie X, Yang H, Jiang H, Cherezov V, ... ... Zhao Q, et al. Structure of the CCR5 chemokine receptor-HIV entry inhibitor maraviroc complex. Science (New York, N.Y.). 341: 1387-90. PMID 24030490 DOI: 10.1126/Science.1241475  0.69
2013 Zhu L, Zhao Q, Wu B. Structure-based studies of chemokine receptors. Current Opinion in Structural Biology. 23: 539-46. PMID 23706951 DOI: 10.1016/J.Sbi.2013.05.003  0.714
2012 Zhao Q, Wu BL. Ice breaking in GPCR structural biology Acta Pharmacologica Sinica. 33: 324-334. PMID 22286917 DOI: 10.1038/Aps.2011.187  0.673
2010 Chien EY, Liu W, Zhao Q, Katritch V, Han GW, Hanson MA, Shi L, Newman AH, Javitch JA, Cherezov V, Stevens RC. Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist. Science (New York, N.Y.). 330: 1091-5. PMID 21097933 DOI: 10.1126/Science.1197410  0.774
2007 Wu B, Liu Y, Zhao Q, Liao S, Zhang J, Bartlam M, Chen W, Rao Z. Crystal structure of RS21-C6, involved in nucleoside triphosphate pyrophosphohydrolysis. Journal of Molecular Biology. 367: 1405-12. PMID 17320107 DOI: 10.1016/J.Jmb.2007.01.057  0.466
2007 Zhao Q, Qin L, Jiang F, Wu B, Yue W, Xu F, Rong Z, Yuan H, Xie X, Gao Y, Bai C, Bartlam M, Pei X, Rao Z. Structure of human spindlin1. Tandem tudor-like domains for cell cycle regulation. The Journal of Biological Chemistry. 282: 647-56. PMID 17082182 DOI: 10.1074/jbc.M604029200  0.445
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