Tanya S. Freedman, PhD - Publications

Affiliations: 
2001-2007 Molecular and Cell Biology University of California, Berkeley, Berkeley, CA, United States 
 2007-2014 Medicine University of California, San Francisco, San Francisco, CA 
 2014- Pharmacology University of Minnesota - Minneapolis 
Website:
http://pharmnas-2165-jh.ahc.umn.edu/~ad%5ctfreedma/

14 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Brian BF, Sauer ML, Greene JT, Senevirathne SE, Lindstedt AJ, Funk OL, Ruis BL, Ramirez LA, Auger JL, Swanson WL, Nunez MG, Moriarity BS, Lowell CA, Binstadt BA, Freedman TS. A dominant function of LynB kinase in preventing autoimmunity. Science Advances. 8: eabj5227. PMID 35452291 DOI: 10.1126/sciadv.abj5227  0.726
2022 Brian BF, Sjaastad FV, Freedman TS. SH3-domain mutations selectively disrupt Csk homodimerization or PTPN22 binding. Scientific Reports. 12: 5875. PMID 35393453 DOI: 10.1038/s41598-022-09589-9  0.746
2021 Greene JT, Brian BF, Senevirathne SE, Freedman TS. Regulation of myeloid-cell activation. Current Opinion in Immunology. 73: 34-42. PMID 34601225 DOI: 10.1016/j.coi.2021.09.004  0.736
2021 Brian Iv BF, Freedman TS. The Src-family kinase Lyn in immunoreceptor signaling. Endocrinology. PMID 34320188 DOI: 10.1210/endocr/bqab152  0.408
2020 Brian BF, Guerrero CR, Freedman TS. Immunopharmacology and Quantitative Analysis of Tyrosine Kinase Signaling. Current Protocols in Immunology. 130: e104. PMID 32931655 DOI: 10.1002/Cpim.104  0.736
2019 Brian BF, Jolicoeur AS, Guerrero CR, Nunez MG, Sychev ZE, Hegre SA, Sætrom P, Habib N, Drake JM, Schwertfeger KL, Freedman TS. Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells. Elife. 8. PMID 31282857 DOI: 10.7554/Elife.46043  0.745
2019 Brian BF, Jolicoeur AS, Guerrero CR, Nunez MG, Sychev ZE, Hegre SA, Sætrom P, Habib N, Drake JM, Schwertfeger KL, Freedman TS. Author response: Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells Elife. DOI: 10.7554/Elife.46043.050  0.417
2015 Freedman TS, Tan YX, Skrzypczynska KM, Manz BN, Sjaastad FV, Goodridge HS, Lowell CA, Weiss A. LynA regulates an inflammation-sensitive signaling checkpoint in macrophages. Elife. 4. PMID 26517880 DOI: 10.7554/Elife.09183  0.611
2015 Freedman TS, Tan YX, Skrzypczynska KM, Manz BN, Sjaastad FV, Goodridge HS, Lowell CA, Weiss A. Author response: LynA regulates an inflammation-sensitive signaling checkpoint in macrophages Elife. DOI: 10.7554/Elife.09183.029  0.495
2014 Tan YX, Manz BN, Freedman TS, Zhang C, Shokat KM, Weiss A. Inhibition of the kinase Csk in thymocytes reveals a requirement for actin remodeling in the initiation of full TCR signaling. Nature Immunology. 15: 186-94. PMID 24317039 DOI: 10.1038/Ni.2772  0.649
2011 Limnander A, Depeille P, Freedman TS, Liou J, Leitges M, Kurosaki T, Roose JP, Weiss A. STIM1, PKC-δ and RasGRP set a threshold for proapoptotic Erk signaling during B cell development. Nature Immunology. 12: 425-33. PMID 21441934 DOI: 10.1038/Ni.2016  0.682
2010 Wang H, Kadlecek TA, Au-Yeung BB, Goodfellow HE, Hsu LY, Freedman TS, Weiss A. ZAP-70: an essential kinase in T-cell signaling. Cold Spring Harbor Perspectives in Biology. 2: a002279. PMID 20452964 DOI: 10.1101/Cshperspect.A002279  0.572
2009 Freedman TS, Sondermann H, Kuchment O, Friedland GD, Kortemme T, Kuriyan J. Differences in flexibility underlie functional differences in the Ras activators son of sevenless and Ras guanine nucleotide releasing factor 1. Structure (London, England : 1993). 17: 41-53. PMID 19141281 DOI: 10.1016/J.Str.2008.11.004  0.636
2006 Freedman TS, Sondermann H, Friedland GD, Kortemme T, Bar-Sagi D, Marqusee S, Kuriyan J. A Ras-induced conformational switch in the Ras activator Son of sevenless. Proceedings of the National Academy of Sciences of the United States of America. 103: 16692-7. PMID 17075039 DOI: 10.1073/Pnas.0608127103  0.733
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