Year |
Citation |
Score |
2023 |
Roche KL, Remiszewski S, Todd MJ, Kulp JL, Tang L, Welsh AV, Barry AP, De C, Reiley WW, Wahl A, Garcia JV, Luftig MA, Shenk T, Tonra JR, Murphy EA, et al. An allosteric inhibitor of sirtuin 2 deacetylase activity exhibits broad-spectrum antiviral activity. The Journal of Clinical Investigation. 133. PMID 37317966 DOI: 10.1172/JCI158978 |
0.317 |
|
2023 |
Goodrum F, Lowen A, Lakdawala S, Alwine J, Casadevall A, Imperiale M, Atwood W, Avgousti D, Baines J, Banfield B, Banks L, Bhaduri-McIntosh S, Bhattacharya D, Blanco-Melo D, Bloom D, ... ... Shenk T, et al. Virology under the Microscope-a Call for Rational Discourse. Msphere. e0003423. PMID 36700653 DOI: 10.1128/msphere.00034-23 |
0.43 |
|
2023 |
Goodrum F, Lowen A, Lakdawala S, Alwine J, Casadevall A, Imperiale M, Atwood W, Avgousti D, Baines J, Banfield B, Banks L, Bhaduri-McIntosh S, Bhattacharya D, Blanco-Melo D, Bloom D, ... ... Shenk T, et al. Virology under the Microscope-a Call for Rational Discourse. Mbio. e0018823. PMID 36700642 DOI: 10.1128/mbio.00188-23 |
0.43 |
|
2023 |
Goodrum F, Lowen A, Lakdawala S, Alwine J, Casadevall A, Imperiale M, Atwood W, Avgousti D, Baines J, Banfield B, Banks L, Bhaduri-McIntosh S, Bhattacharya D, Blanco-Melo D, Bloom D, ... ... Shenk T, et al. Virology under the Microscope-a Call for Rational Discourse. Journal of Virology. e0008923. PMID 36700640 DOI: 10.1128/jvi.00089-23 |
0.43 |
|
2021 |
Naseri-Nosar P, Nogalski MT, Shenk T. The aryl hydrocarbon receptor facilitates the human cytomegalovirus-mediated G1/S block to cell cycle progression. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33723080 DOI: 10.1073/pnas.2026336118 |
0.329 |
|
2019 |
Chen S, Shenk T, Nogalski MT. P2Y2 purinergic receptor modulates virus yield, calcium homeostasis, and cell motility in human cytomegalovirus-infected cells. Proceedings of the National Academy of Sciences of the United States of America. 116: 18971-18982. PMID 31481624 DOI: 10.1073/Pnas.1907562116 |
0.51 |
|
2019 |
Nogalski MT, Solovyov A, Kulkarni AS, Desai N, Oberstein A, Levine AJ, Ting DT, Shenk T, Greenbaum BD. A tumor-specific endogenous repetitive element is induced by herpesviruses. Nature Communications. 10: 90. PMID 30626867 DOI: 10.1038/S41467-018-07944-X |
0.471 |
|
2018 |
Wu K, Oberstein A, Wang W, Shenk T. Role of PDGF receptor-α during human cytomegalovirus entry into fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. PMID 30275317 DOI: 10.1073/Pnas.1806305115 |
0.501 |
|
2017 |
Oberstein A, Shenk T. Cellular responses to human cytomegalovirus infection: Induction of a mesenchymal-to-epithelial transition (MET) phenotype. Proceedings of the National Academy of Sciences of the United States of America. PMID 28874566 DOI: 10.1073/Pnas.1710799114 |
0.429 |
|
2015 |
Ziehr B, Lenarcic E, Vincent HA, Cecil C, Garcia B, Shenk T, Moorman NJ. Human cytomegalovirus TRS1 protein associates with the 7-methylguanosine mRNA cap and facilitates translation. Proteomics. 15: 1983-94. PMID 25894605 DOI: 10.1002/Pmic.201400616 |
0.454 |
|
2015 |
Oberstein A, Perlman DH, Shenk T, Terry LJ. Human cytomegalovirus pUL97 kinase induces global changes in the infected cell phosphoproteome. Proteomics. 15: 2006-22. PMID 25867546 DOI: 10.1002/Pmic.201400607 |
0.423 |
|
2015 |
Purdy JG, Shenk T, Rabinowitz JD. Fatty acid elongase 7 catalyzes lipidome remodeling essential for human cytomegalovirus replication. Cell Reports. 10: 1375-85. PMID 25732827 DOI: 10.1016/J.Celrep.2015.02.003 |
0.426 |
|
2014 |
Shenk T, Alwine JC. Human Cytomegalovirus: Coordinating Cellular Stress, Signaling, and Metabolic Pathways. Annual Review of Virology. 1: 355-74. PMID 26958726 DOI: 10.1146/Annurev-Virology-031413-085425 |
0.454 |
|
2014 |
Koyuncu E, Budayeva HG, Miteva YV, Ricci DP, Silhavy TJ, Shenk T, Cristea IM. Sirtuins are evolutionarily conserved viral restriction factors. Mbio. 5. PMID 25516616 DOI: 10.1128/Mbio.02249-14 |
0.504 |
|
2014 |
Hwang J, Purdy JG, Wu K, Rabinowitz JD, Shenk T. Estrogen-related receptor α is required for efficient human cytomegalovirus replication. Proceedings of the National Academy of Sciences of the United States of America. 111: E5706-15. PMID 25512541 DOI: 10.1073/Pnas.1422361112 |
0.633 |
|
2014 |
Casadevall A, Shenk T. mBio addresses the pause in gain-of-function (GOF) experiments involving pathogens with pandemic potential (PPP). Mbio. 5. PMID 25505126 DOI: 10.1128/Mbio.02434-14 |
0.319 |
|
2014 |
Dermody TS, Casadevall A, Imperiale MJ, Sandri-Goldin RM, Shenk T. The decision to publish an avian H7N1 influenza virus gain-of-function experiment. Mbio. 5: e01985-14. PMID 25316699 DOI: 10.1128/Mbio.01985-14 |
0.349 |
|
2014 |
O'Connor CM, DiMaggio PA, Shenk T, Garcia BA. Quantitative proteomic discovery of dynamic epigenome changes that control human cytomegalovirus (HCMV) infection. Molecular & Cellular Proteomics : McP. 13: 2399-410. PMID 24987098 DOI: 10.1074/Mcp.M114.039792 |
0.415 |
|
2014 |
Dermody TS, Sandri-Goldin RM, Shenk T. Sequence changes associated with respiratory transmission of H7N1 influenza virus in mammals. Journal of Virology. 88: 6533-4. PMID 24696481 DOI: 10.1128/Jvi.00886-14 |
0.33 |
|
2014 |
Sharon-Friling R, Shenk T. Human cytomegalovirus pUL37x1-induced calcium flux activates PKCα, inducing altered cell shape and accumulation of cytoplasmic vesicles. Proceedings of the National Academy of Sciences of the United States of America. 111: E1140-8. PMID 24616524 DOI: 10.1073/Pnas.1402515111 |
0.412 |
|
2013 |
Grady SL, Purdy JG, Rabinowitz JD, Shenk T. Argininosuccinate synthetase 1 depletion produces a metabolic state conducive to herpes simplex virus 1 infection. Proceedings of the National Academy of Sciences of the United States of America. 110: E5006-15. PMID 24297925 DOI: 10.1073/Pnas.1321305110 |
0.801 |
|
2013 |
Koyuncu E, Purdy JG, Rabinowitz JD, Shenk T. Saturated very long chain fatty acids are required for the production of infectious human cytomegalovirus progeny. Plos Pathogens. 9: e1003333. PMID 23696731 DOI: 10.1371/Journal.Ppat.1003333 |
0.331 |
|
2013 |
Dermody TS, Sandri-Goldin RM, Shenk T. A new determinant of H5N1 influenza virus pathogenesis in mammals. Journal of Virology. 87: 4795-6. PMID 23449798 DOI: 10.1128/Jvi.00474-13 |
0.358 |
|
2013 |
Teng MW, Bolovan-Fritts C, Dar RD, Womack A, Simpson ML, Shenk T, Weinberger LS. Erratum: An endogenous accelerator for viral gene expression confers a fitness advantage (Cell (2012) 151 (1569-1580)) Cell. 152. DOI: 10.1016/J.Cell.2013.01.048 |
0.796 |
|
2012 |
Teng MW, Bolovan-Fritts C, Dar RD, Womack A, Simpson ML, Shenk T, Weinberger LS. An endogenous accelerator for viral gene expression confers a fitness advantage. Cell. 151: 1569-80. PMID 23260143 DOI: 10.1016/J.Cell.2012.11.051 |
0.789 |
|
2012 |
Casadevall A, Shenk T. The H5N1 moratorium controversy and debate. Mbio. 3. PMID 23047753 DOI: 10.1128/Mbio.00379-12 |
0.351 |
|
2012 |
O'Connor CM, Shenk T. Human cytomegalovirus pUL78 G protein-coupled receptor homologue is required for timely cell entry in epithelial cells but not fibroblasts. Journal of Virology. 86: 11425-33. PMID 22915800 DOI: 10.1128/Jvi.05900-11 |
0.543 |
|
2012 |
Gudleski-O'Regan N, Greco TM, Cristea IM, Shenk T. Increased expression of LDL receptor-related protein 1 during human cytomegalovirus infection reduces virion cholesterol and infectivity. Cell Host & Microbe. 12: 86-96. PMID 22817990 DOI: 10.1016/J.Chom.2012.05.012 |
0.473 |
|
2012 |
Lee SH, Kalejta RF, Kerry J, Semmes OJ, O'Connor CM, Khan Z, Garcia BA, Shenk T, Murphy E. BclAF1 restriction factor is neutralized by proteasomal degradation and microRNA repression during human cytomegalovirus infection. Proceedings of the National Academy of Sciences of the United States of America. 109: 9575-80. PMID 22645331 DOI: 10.1073/Pnas.1207496109 |
0.542 |
|
2012 |
Grady SL, Hwang J, Vastag L, Rabinowitz JD, Shenk T. Herpes simplex virus 1 infection activates poly(ADP-ribose) polymerase and triggers the degradation of poly(ADP-ribose) glycohydrolase. Journal of Virology. 86: 8259-68. PMID 22623791 DOI: 10.1128/Jvi.00495-12 |
0.821 |
|
2012 |
Casadevall A, Shenk T. Mammalian-transmissible H5N1 virus: containment level and case fatality ratio. Mbio. 3: e00054-12. PMID 22396484 DOI: 10.1128/Mbio.00054-12 |
0.323 |
|
2012 |
Terry LJ, Vastag L, Rabinowitz JD, Shenk T. Human kinome profiling identifies a requirement for AMP-activated protein kinase during human cytomegalovirus infection. Proceedings of the National Academy of Sciences of the United States of America. 109: 3071-6. PMID 22315427 DOI: 10.1073/Pnas.1200494109 |
0.406 |
|
2011 |
Rabinowitz JD, Purdy JG, Vastag L, Shenk T, Koyuncu E. Metabolomics in drug target discovery. Cold Spring Harbor Symposia On Quantitative Biology. 76: 235-46. PMID 22114327 DOI: 10.1101/Sqb.2011.76.010694 |
0.325 |
|
2011 |
Vastag L, Koyuncu E, Grady SL, Shenk TE, Rabinowitz JD. Divergent effects of human cytomegalovirus and herpes simplex virus-1 on cellular metabolism. Plos Pathogens. 7: e1002124. PMID 21779165 DOI: 10.1371/Journal.Ppat.1002124 |
0.779 |
|
2011 |
Liu ST, Sharon-Friling R, Ivanova P, Milne SB, Myers DS, Rabinowitz JD, Brown HA, Shenk T. Synaptic vesicle-like lipidome of human cytomegalovirus virions reveals a role for SNARE machinery in virion egress. Proceedings of the National Academy of Sciences of the United States of America. 108: 12869-74. PMID 21768361 DOI: 10.1073/Pnas.1109796108 |
0.621 |
|
2011 |
O'Connor CM, Shenk T. Human cytomegalovirus pUS27 G protein-coupled receptor homologue is required for efficient spread by the extracellular route but not for direct cell-to-cell spread. Journal of Virology. 85: 3700-7. PMID 21307184 DOI: 10.1128/Jvi.02442-10 |
0.531 |
|
2010 |
Womack A, Shenk T. Human cytomegalovirus tegument protein pUL71 is required for efficient virion egress. Mbio. 1. PMID 21151777 DOI: 10.1128/Mbio.00282-10 |
0.826 |
|
2010 |
Hargett D, Shenk TE. Experimental human cytomegalovirus latency in CD14+ monocytes. Proceedings of the National Academy of Sciences of the United States of America. 107: 20039-44. PMID 21041645 DOI: 10.1073/Pnas.1014509107 |
0.471 |
|
2010 |
Terhune SS, Moorman NJ, Cristea IM, Savaryn JP, Cuevas-Bennett C, Rout MP, Chait BT, Shenk T. Human cytomegalovirus UL29/28 protein interacts with components of the NuRD complex which promote accumulation of immediate-early RNA. Plos Pathogens. 6: e1000965. PMID 20585571 DOI: 10.1371/Journal.Ppat.1000965 |
0.475 |
|
2010 |
Cristea IM, Moorman NJ, Terhune SS, Cuevas CD, O'Keefe ES, Rout MP, Chait BT, Shenk T. Human cytomegalovirus pUL83 stimulates activity of the viral immediate-early promoter through its interaction with the cellular IFI16 protein. Journal of Virology. 84: 7803-14. PMID 20504932 DOI: 10.1128/Jvi.00139-10 |
0.836 |
|
2010 |
Moorman NJ, Shenk T. Rapamycin-resistant mTORC1 kinase activity is required for herpesvirus replication. Journal of Virology. 84: 5260-9. PMID 20181700 DOI: 10.1128/Jvi.02733-09 |
0.416 |
|
2010 |
Aoyagi M, Gaspar M, Shenk TE. Human cytomegalovirus UL69 protein facilitates translation by associating with the mRNA cap-binding complex and excluding 4EBP1. Proceedings of the National Academy of Sciences of the United States of America. 107: 2640-5. PMID 20133758 DOI: 10.1073/Pnas.0914856107 |
0.437 |
|
2010 |
Moorman NJ, Sharon-Friling R, Shenk T, Cristea IM. A targeted spatial-temporal proteomics approach implicates multiple cellular trafficking pathways in human cytomegalovirus virion maturation. Molecular & Cellular Proteomics : McP. 9: 851-60. PMID 20023299 DOI: 10.1074/Mcp.M900485-Mcp200 |
0.476 |
|
2009 |
Mitchell DP, Savaryn JP, Moorman NJ, Shenk T, Terhune SS. Human cytomegalovirus UL28 and UL29 open reading frames encode a spliced mRNA and stimulate accumulation of immediate-early RNAs. Journal of Virology. 83: 10187-97. PMID 19625400 DOI: 10.1128/Jvi.00396-09 |
0.687 |
|
2008 |
Lilja AE, Shenk T. Efficient replication of rhesus cytomegalovirus variants in multiple rhesus and human cell types. Proceedings of the National Academy of Sciences of the United States of America. 105: 19950-5. PMID 19064925 DOI: 10.1073/Pnas.0811063106 |
0.453 |
|
2008 |
Schröer J, Shenk T. Inhibition of cyclooxygenase activity blocks cell-to-cell spread of human cytomegalovirus. Proceedings of the National Academy of Sciences of the United States of America. 105: 19468-73. PMID 19033472 DOI: 10.1073/Pnas.0810740105 |
0.4 |
|
2008 |
Cuevas-Bennett C, Shenk T. Dynamic histone H3 acetylation and methylation at human cytomegalovirus promoters during replication in fibroblasts. Journal of Virology. 82: 9525-36. PMID 18653451 DOI: 10.1128/Jvi.00946-08 |
0.326 |
|
2008 |
Moorman NJ, Cristea IM, Terhune SS, Rout MP, Chait BT, Shenk T. Human cytomegalovirus protein UL38 inhibits host cell stress responses by antagonizing the tuberous sclerosis protein complex. Cell Host & Microbe. 3: 253-62. PMID 18407068 DOI: 10.1016/J.Chom.2008.03.002 |
0.484 |
|
2008 |
Murphy E, VanÃcek J, Robins H, Shenk T, Levine AJ. Suppression of immediate-early viral gene expression by herpesvirus-coded microRNAs: implications for latency. Proceedings of the National Academy of Sciences of the United States of America. 105: 5453-8. PMID 18378902 DOI: 10.1073/Pnas.0711910105 |
0.442 |
|
2008 |
Lilja AE, Chang WL, Barry PA, Becerra SP, Shenk TE. Functional genetic analysis of rhesus cytomegalovirus: Rh01 is an epithelial cell tropism factor. Journal of Virology. 82: 2170-81. PMID 18094178 DOI: 10.1128/Jvi.02316-07 |
0.526 |
|
2007 |
Wang D, Yu QC, Schröer J, Murphy E, Shenk T. Human cytomegalovirus uses two distinct pathways to enter retinal pigmented epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 20037-42. PMID 18077432 DOI: 10.1073/Pnas.0709704104 |
0.495 |
|
2007 |
Goodrum F, Reeves M, Sinclair J, High K, Shenk T. Human cytomegalovirus sequences expressed in latently infected individuals promote a latent infection in vitro. Blood. 110: 937-45. PMID 17440050 DOI: 10.1182/Blood-2007-01-070078 |
0.487 |
|
2007 |
Terhune S, Torigoi E, Moorman N, Silva M, Qian Z, Shenk T, Yu D. Human cytomegalovirus UL38 protein blocks apoptosis. Journal of Virology. 81: 3109-23. PMID 17202209 DOI: 10.1128/Jvi.02124-06 |
0.501 |
|
2007 |
Weinberger LS, Shenk T. An HIV feedback resistor: auto-regulatory circuit deactivator and noise buffer. Plos Biology. 5: e9. PMID 17194214 DOI: 10.1371/Journal.Pbio.0050009 |
0.639 |
|
2006 |
Munger J, Bajad SU, Coller HA, Shenk T, Rabinowitz JD. Dynamics of the cellular metabolome during human cytomegalovirus infection. Plos Pathogens. 2: e132. PMID 17173481 DOI: 10.1371/Journal.Ppat.0020132 |
0.404 |
|
2006 |
Sharon-Friling R, Goodhouse J, Colberg-Poley AM, Shenk T. Human cytomegalovirus pUL37x1 induces the release of endoplasmic reticulum calcium stores. Proceedings of the National Academy of Sciences of the United States of America. 103: 19117-22. PMID 17135350 DOI: 10.1073/Pnas.0609353103 |
0.326 |
|
2006 |
Kulesza CA, Shenk T. Murine cytomegalovirus encodes a stable intron that facilitates persistent replication in the mouse. Proceedings of the National Academy of Sciences of the United States of America. 103: 18302-7. PMID 17105807 DOI: 10.1073/Pnas.0608718103 |
0.48 |
|
2006 |
Feng X, Schröer J, Yu D, Shenk T. Human cytomegalovirus pUS24 is a virion protein that functions very early in the replication cycle. Journal of Virology. 80: 8371-8. PMID 16912288 DOI: 10.1128/Jvi.00399-06 |
0.673 |
|
2006 |
Munger J, Yu D, Shenk T. UL26-deficient human cytomegalovirus produces virions with hypophosphorylated pp28 tegument protein that is unstable within newly infected cells. Journal of Virology. 80: 3541-8. PMID 16537622 DOI: 10.1128/Jvi.80.7.3541-3548.2006 |
0.503 |
|
2006 |
Gaspar M, Shenk T. Human cytomegalovirus inhibits a DNA damage response by mislocalizing checkpoint proteins. Proceedings of the National Academy of Sciences of the United States of America. 103: 2821-6. PMID 16477038 DOI: 10.1073/Pnas.0511148103 |
0.41 |
|
2005 |
Wang D, Shenk T. Human cytomegalovirus virion protein complex required for epithelial and endothelial cell tropism. Proceedings of the National Academy of Sciences of the United States of America. 102: 18153-8. PMID 16319222 DOI: 10.1073/Pnas.0509201102 |
0.32 |
|
2005 |
Wang D, Shenk T. Human cytomegalovirus UL131 open reading frame is required for epithelial cell tropism. Journal of Virology. 79: 10330-8. PMID 16051825 DOI: 10.1128/Jvi.79.16.10330-10338.2005 |
0.464 |
|
2005 |
Silva MC, Schröer J, Shenk T. Human cytomegalovirus cell-to-cell spread in the absence of an essential assembly protein. Proceedings of the National Academy of Sciences of the United States of America. 102: 2081-6. PMID 15684067 DOI: 10.1073/Pnas.0409597102 |
0.521 |
|
2004 |
Nevels M, Paulus C, Shenk T. Human cytomegalovirus immediate-early 1 protein facilitates viral replication by antagonizing histone deacetylation. Proceedings of the National Academy of Sciences of the United States of America. 101: 17234-9. PMID 15572445 DOI: 10.1073/Pnas.0407933101 |
0.48 |
|
2004 |
Kulesza CA, Shenk T. Human cytomegalovirus 5-kilobase immediate-early RNA is a stable intron. Journal of Virology. 78: 13182-9. PMID 15542670 DOI: 10.1128/Jvi.78.23.13182-13189.2004 |
0.418 |
|
2004 |
Wang D, Bresnahan W, Shenk T. Human cytomegalovirus encodes a highly specific RANTES decoy receptor. Proceedings of the National Academy of Sciences of the United States of America. 101: 16642-7. PMID 15536129 DOI: 10.1073/Pnas.0407233101 |
0.462 |
|
2004 |
Varnum SM, Streblow DN, Monroe ME, Smith P, Auberry KJ, Pasa-Tolic L, Wang D, Camp DG, Rodland K, Wiley S, Britt W, Shenk T, Smith RD, Nelson JA. Identification of proteins in human cytomegalovirus (HCMV) particles: the HCMV proteome. Journal of Virology. 78: 10960-6. PMID 15452216 DOI: 10.1128/JVI.78.20.10960-10966.2004 |
0.475 |
|
2004 |
Terhune SS, Schröer J, Shenk T. RNAs are packaged into human cytomegalovirus virions in proportion to their intracellular concentration. Journal of Virology. 78: 10390-8. PMID 15367605 DOI: 10.1128/Jvi.78.19.10390-10398.2004 |
0.466 |
|
2004 |
Adamo JE, Schröer J, Shenk T. Human cytomegalovirus TRS1 protein is required for efficient assembly of DNA-containing capsids. Journal of Virology. 78: 10221-9. PMID 15367587 DOI: 10.1128/Jvi.78.19.10221-10229.2004 |
0.511 |
|
2004 |
Nevels M, Brune W, Shenk T. SUMOylation of the human cytomegalovirus 72-kilodalton IE1 protein facilitates expression of the 86-kilodalton IE2 protein and promotes viral replication. Journal of Virology. 78: 7803-12. PMID 15220454 DOI: 10.1128/Jvi.78.14.7803-7812.2004 |
0.511 |
|
2004 |
Goodrum F, Jordan CT, Terhune SS, High K, Shenk T. Differential outcomes of human cytomegalovirus infection in primitive hematopoietic cell subpopulations. Blood. 104: 687-95. PMID 15090458 DOI: 10.1182/Blood-2003-12-4344 |
0.355 |
|
2004 |
Challacombe JF, Rechtsteiner A, Gottardo R, Rocha LM, Browne EP, Shenk T, Altherr MR, Brettin TS. Evaluation of the host transcriptional response to human cytomegalovirus infection. Physiological Genomics. 18: 51-62. PMID 15069167 DOI: 10.1152/Physiolgenomics.00155.2003 |
0.689 |
|
2004 |
Goodrum FD, Jordan CT, Terhune SS, High KP, Shenk T. Human Cytomegalovirus Infection of Primitive Hematopoietic Progenitor Cells: A Model for Latency. Blood. 104: 1703-1703. DOI: 10.1182/Blood.V104.11.1703.1703 |
0.407 |
|
2003 |
Murphy E, Rigoutsos I, Shibuya T, Shenk TE. Reevaluation of human cytomegalovirus coding potential. Proceedings of the National Academy of Sciences of the United States of America. 100: 13585-90. PMID 14593199 DOI: 10.1073/Pnas.1735466100 |
0.351 |
|
2003 |
Brune W, Nevels M, Shenk T. Murine cytomegalovirus m41 open reading frame encodes a Golgi-localized antiapoptotic protein. Journal of Virology. 77: 11633-43. PMID 14557649 DOI: 10.1128/Jvi.77.21.11633-11643.2003 |
0.419 |
|
2003 |
Yu D, Silva MC, Shenk T. Functional map of human cytomegalovirus AD169 defined by global mutational analysis. Proceedings of the National Academy of Sciences of the United States of America. 100: 12396-401. PMID 14519856 DOI: 10.1073/Pnas.1635160100 |
0.401 |
|
2003 |
Browne EP, Shenk T. Human cytomegalovirus UL83-coded pp65 virion protein inhibits antiviral gene expression in infected cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 11439-44. PMID 12972646 DOI: 10.1073/Pnas.1534570100 |
0.765 |
|
2003 |
Silva MC, Yu QC, Enquist L, Shenk T. Human cytomegalovirus UL99-encoded pp28 is required for the cytoplasmic envelopment of tegument-associated capsids. Journal of Virology. 77: 10594-605. PMID 12970444 DOI: 10.1128/Jvi.77.19.10594-10605.2003 |
0.56 |
|
2003 |
Rigoutsos I, Novotny J, Huynh T, Chin-Bow ST, Parida L, Platt D, Coleman D, Shenk T. In silico pattern-based analysis of the human cytomegalovirus genome. Journal of Virology. 77: 4326-44. PMID 12634390 DOI: 10.1128/Jvi.77.7.4326-4344.2003 |
0.396 |
|
2003 |
Kalejta RF, Shenk T. Proteasome-dependent, ubiquitin-independent degradation of the Rb family of tumor suppressors by the human cytomegalovirus pp71 protein. Proceedings of the National Academy of Sciences of the United States of America. 100: 3263-8. PMID 12626766 DOI: 10.1073/Pnas.0538058100 |
0.345 |
|
2003 |
Kalejta RF, Bechtel JT, Shenk T. Human cytomegalovirus pp71 stimulates cell cycle progression by inducing the proteasome-dependent degradation of the retinoblastoma family of tumor suppressors. Molecular and Cellular Biology. 23: 1885-95. PMID 12612064 DOI: 10.1128/Mcb.23.6.1885-1895.2003 |
0.786 |
|
2003 |
Kalejta RF, Shenk T. The human cytomegalovirus UL82 gene product (pp71) accelerates progression through the G1 phase of the cell cycle. Journal of Virology. 77: 3451-9. PMID 12610120 DOI: 10.1128/Jvi.77.6.3451-3459.2003 |
0.387 |
|
2002 |
Goodrum FD, Jordan CT, High K, Shenk T. Human cytomegalovirus gene expression during infection of primary hematopoietic progenitor cells: a model for latency. Proceedings of the National Academy of Sciences of the United States of America. 99: 16255-60. PMID 12456880 DOI: 10.1073/Pnas.252630899 |
0.347 |
|
2002 |
Blankenship CA, Shenk T. Mutant human cytomegalovirus lacking the immediate-early TRS1 coding region exhibits a late defect. Journal of Virology. 76: 12290-9. PMID 12414969 DOI: 10.1128/Jvi.76.23.12290-12299.2002 |
0.82 |
|
2002 |
Shenk T. Might a vanguard of mRNAs prepare cells for the arrival of herpes simplex virus? Proceedings of the National Academy of Sciences of the United States of America. 99: 8465-6. PMID 12084908 DOI: 10.1073/pnas.152301499 |
0.336 |
|
2002 |
Zhu H, Cong JP, Yu D, Bresnahan WA, Shenk TE. Inhibition of cyclooxygenase 2 blocks human cytomegalovirus replication. Proceedings of the National Academy of Sciences of the United States of America. 99: 3932-7. PMID 11867761 DOI: 10.1073/Pnas.052713799 |
0.47 |
|
2002 |
Heider JA, Bresnahan WA, Shenk TE. Construction of a rationally designed human cytomegalovirus variant encoding a temperature-sensitive immediate-early 2 protein. Proceedings of the National Academy of Sciences of the United States of America. 99: 3141-6. PMID 11867756 DOI: 10.1073/Pnas.052710599 |
0.474 |
|
2002 |
Kalejta RF, Shenk T. Manipulation of the cell cycle by human cytomegalovirus. Frontiers in Bioscience : a Journal and Virtual Library. 7: d295-306. PMID 11779699 DOI: 10.2741/Kalejta |
0.422 |
|
2002 |
Bechtel JT, Shenk T. Human cytomegalovirus UL47 tegument protein functions after entry and before immediate-early gene expression. Journal of Virology. 76: 1043-50. PMID 11773380 DOI: 10.1128/Jvi.76.3.1043-1050.2002 |
0.828 |
|
2002 |
Heider JA, Yu Y, Shenk T, Alwine JC. Characterization of a human cytomegalovirus with phosphorylation site mutations in the immediate-early 2 protein. Journal of Virology. 76: 928-32. PMID 11752183 DOI: 10.1128/Jvi.76.2.928-932.2002 |
0.498 |
|
2001 |
Browne EP, Wing B, Coleman D, Shenk T. Altered cellular mRNA levels in human cytomegalovirus-infected fibroblasts: viral block to the accumulation of antiviral mRNAs. Journal of Virology. 75: 12319-30. PMID 11711622 DOI: 10.1128/Jvi.75.24.12319-12330.2001 |
0.724 |
|
2001 |
Novotny J, Rigoutsos I, Coleman D, Shenk T. In silico structural and functional analysis of the human cytomegalovirus (HHV5) genome Journal of Molecular Biology. 310: 1151-1166. PMID 11502002 DOI: 10.1006/Jmbi.2001.4798 |
0.356 |
|
2001 |
Oliveira SA, Shenk TE. Murine cytomegalovirus M78 protein, a G protein-coupled receptor homologue, is a constituent of the virion and facilitates accumulation of immediate-early viral mRNA. Proceedings of the National Academy of Sciences of the United States of America. 98: 3237-42. PMID 11248062 DOI: 10.1073/Pnas.051629898 |
0.445 |
|
2000 |
Bresnahan WA, Shenk TE. UL82 virion protein activates expression of immediate early viral genes in human cytomegalovirus-infected cells. Proceedings of the National Academy of Sciences of the United States of America. 97: 14506-11. PMID 11121054 DOI: 10.1073/Pnas.97.26.14506 |
0.54 |
|
2000 |
Tullis GE, Shenk T. Efficient replication of adeno-associated virus type 2 vectors: A cis-acting element outside of the terminal repeats and a minimal size Journal of Virology. 74: 11511-11521. PMID 11090148 DOI: 10.1128/Jvi.74.24.11511-11521.2000 |
0.435 |
|
2000 |
Bresnahan WA, Hultman GE, Shenk T. Replication of wild-type and mutant human cytomegalovirus in life-extended human diploid fibroblasts Journal of Virology. 74: 10816-10818. PMID 11044129 DOI: 10.1128/Jvi.74.22.10816-10818.2000 |
0.419 |
|
2000 |
Bresnahan WA, Shenk T. A subset of viral transcripts packaged within human cytomegalovirus particles Science. 288: 2373-2376. PMID 10875924 DOI: 10.1126/Science.288.5475.2373 |
0.518 |
|
2000 |
Hayashi ML, Blankenship C, Shenk T. Human cytomegalovirus UL69 protein is required for efficient accumulation of infected cells in the G1 phase of the cell cycle Proceedings of the National Academy of Sciences of the United States of America. 97: 2692-2696. PMID 10706637 DOI: 10.1073/Pnas.050587597 |
0.82 |
|
1999 |
Horikoshi N, Cong J, Kley N, Shenk T. Isolation of differentially expressed cDNAs from p53-dependent apoptotic cells: activation of the human homologue of the Drosophila peroxidasin gene. Biochemical and Biophysical Research Communications. 261: 864-9. PMID 10441517 DOI: 10.1006/Bbrc.1999.1123 |
0.302 |
|
1999 |
Patterson CE, Shenk T. Human cytomegalovirus UL36 protein is dispensable for viral replication in cultured cells Journal of Virology. 73: 7126-7131. PMID 10438798 DOI: 10.1128/Jvi.73.9.7126-7131.1999 |
0.472 |
|
1999 |
Mansuo LU, Shenk T. Human cytomegalovirus UL69 protein induces cells to accumulate in G1 phase of the cell cycle Journal of Virology. 73: 676-683. PMID 9847373 DOI: 10.1128/Jvi.73.1.676-683.1999 |
0.422 |
|
1999 |
Hirsch AJ, Shenk T. Human cytomegalovirus inhibits transcription of the CC chemokine MCP-1 gene Journal of Virology. 73: 404-410. PMID 9847345 DOI: 10.1128/Jvi.73.1.404-410.1999 |
0.472 |
|
1998 |
Higashino F, Pipas JM, Shenk T. Adenovirus E4orf6 oncoprotein modulates the function of the p53-related protein, p73 Proceedings of the National Academy of Sciences of the United States of America. 95: 15683-15687. PMID 9861030 DOI: 10.1073/Pnas.95.26.15683 |
0.33 |
|
1998 |
Zhu H, Cong JP, Mamtora G, Gingeras T, Shenk T. Cellular gene expression altered by human cytomegalovirus: global monitoring with oligonucleotide arrays. Proceedings of the National Academy of Sciences of the United States of America. 95: 14470-5. PMID 9826724 DOI: 10.1073/Pnas.95.24.14470 |
0.384 |
|
1998 |
Gabler S, Schütt H, Groitl P, Wolf H, Shenk T, Dobner T. E1B 55-kilodalton-associated protein: a cellular protein with RNA-binding activity implicated in nucleocytoplasmic transport of adenovirus and cellular mRNAs. Journal of Virology. 72: 7960-71. PMID 9733834 |
0.373 |
|
1998 |
Roth J, Dobbelstein M, Freedman D, Shenk T, Levine A. Nucleo-cytoplasmic shuttling of the HDM2 oncoprotein regulates the levels of P53 protein VIA a pathway USED by the human immunodeficiency virus REV protein Gastroenterology. 114: A669. DOI: 10.1016/S0016-5085(98)82742-X |
0.326 |
|
1997 |
Flint J, Shenk T. Viral transactivating proteins Annual Review of Genetics. 31: 177-212. PMID 9442894 DOI: 10.1146/Annurev.Genet.31.1.177 |
0.462 |
|
1997 |
Kalejta RF, Shenk T, Beavis AJ. Use of a membrane-localized green fluorescent protein allows simultaneous identification of transfected cells and cell cycle analysis by flow cytometry Cytometry. 29: 286-291. PMID 9415410 DOI: 10.1002/(Sici)1097-0320(19971201)29:4<286::Aid-Cyto4>3.0.Co;2-8 |
0.352 |
|
1997 |
Zhu H, Cong JP, Shenk T. Use of differential display analysis to assess the effect of human cytomegalovirus infection on the accumulation of cellular RNAs: Induction of interferon-responsive RNAs Proceedings of the National Academy of Sciences of the United States of America. 94: 13985-13990. PMID 9391139 DOI: 10.1073/Pnas.94.25.13985 |
0.482 |
|
1997 |
Parks CL, Shenk T. Activation of the adenovirus major late promoter by transcription factors MAZ and Sp1 Journal of Virology. 71: 9600-9607. PMID 9371624 DOI: 10.1128/Jvi.71.12.9600-9607.1997 |
0.337 |
|
1997 |
Dobbelstein M, Roth J, Kimberly WT, Levine AJ, Shenk T. Nuclear export of the E1B 55-kDa and E4 34-kDa adenoviral oncoproteins mediated by a rev-like signal sequence. The Embo Journal. 16: 4276-84. PMID 9250671 DOI: 10.1093/Emboj/16.14.4276 |
0.367 |
|
1997 |
Romanowski MJ, Garrido-Guerrero E, Shenk T. pIRS1 and pTRS1 are present in human cytomegalovirus virions Journal of Virology. 71: 5703-5705. PMID 9188653 DOI: 10.1128/Jvi.71.7.5703-5705.1997 |
0.478 |
|
1997 |
Baldick CJ, Marchini A, Patterson CE, Shenk T. Human cytomegalovirus tegument protein pp71 (ppUL82) enhances the infectivity of viral DNA and accelerates the infectious cycle Journal of Virology. 71: 4400-4408. PMID 9151830 DOI: 10.1128/Jvi.71.6.4400-4408.1997 |
0.489 |
|
1997 |
Shen Y, Zhu H, Shenk T. Human cytomegalovirus IE1 and IE2 proteins are mutagenic and mediate 'hit-and-run' oncogenic transformation in cooperation with the adenovirus E1A proteins Proceedings of the National Academy of Sciences of the United States of America. 94: 3341-3345. PMID 9096395 DOI: 10.1073/Pnas.94.7.3341 |
0.454 |
|
1997 |
Romanowski MJ, Shenk T. Characterization of the human cytomegalovirus irs1 and trs1 genes: A second immediate-early transcription unit within irs1 whose product antagonizes transcriptional activation Journal of Virology. 71: 1485-1496. PMID 8995674 DOI: 10.1128/Jvi.71.2.1485-1496.1997 |
0.466 |
|
1996 |
Houbaviy HB, Usheva A, Shenk T, Burley SK. Cocrystal structure of YY1 bound to the adeno-associated virus P5 initiator Proceedings of the National Academy of Sciences of the United States of America. 93: 13577-13582. PMID 8942976 DOI: 10.1073/Pnas.93.24.13577 |
0.378 |
|
1996 |
Usheva A, Shenk T. YY1 transcriptional initiator: Protein interactions and association with a DNA site containing unpaired strands Proceedings of the National Academy of Sciences of the United States of America. 93: 13571-13576. PMID 8942975 DOI: 10.1073/Pnas.93.24.13571 |
0.326 |
|
1996 |
Moore M, Horikoshi N, Shenk T. Oncogenic potential of the adenovirus E4orf6 protein Proceedings of the National Academy of Sciences of the United States of America. 93: 11295-11301. PMID 8876129 DOI: 10.1073/Pnas.93.21.11295 |
0.38 |
|
1996 |
Wang ZY, Qiu QQ, Seufert W, Taguchi T, Testa JR, Whitmore SA, Callen DF, Welsh D, Shenk T, Deuel TF. Molecular cloning of the cDNA and chromosome localization of the gene for human ubiquitin-conjugating enzyme 9. The Journal of Biological Chemistry. 271: 24811-6. PMID 8798754 DOI: 10.1074/Jbc.271.40.24811 |
0.362 |
|
1996 |
Dobbelstein M, Shenk T. Protection against apoptosis by the vaccinia virus SPI-2 (B13R) gene product Journal of Virology. 70: 6479-6485. PMID 8709286 DOI: 10.1128/Jvi.70.9.6479-6485.1996 |
0.429 |
|
1996 |
Goodrum FD, Shenk T, Ornelles DA. Adenovirus early region 4 34-kilodalton protein directs the nuclear localization of the early region 1B 55-kilodalton protein in primate cells Journal of Virology. 70: 6323-6335. PMID 8709260 DOI: 10.1128/Jvi.70.9.6323-6335.1996 |
0.384 |
|
1996 |
Baldick CJ, Shenk T. Proteins associated with purified human cytomegalovirus particles Journal of Virology. 70: 6097-6105. PMID 8709233 |
0.313 |
|
1996 |
Ferrari FK, Samulski T, Shenk T, Samulski RJ. Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors Journal of Virology. 70: 3227-3234. PMID 8627803 DOI: 10.1128/Jvi.70.5.3227-3234.1996 |
0.589 |
|
1996 |
Ferrari FK, Samulski T, Shenk T, Samulski RJ. Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors. Journal of Virology. 70: 3227-3234. DOI: 10.1128/jvi.70.5.3227-3234.1996 |
0.521 |
|
1996 |
Elenbaas B, Dobbelstein M, Roth J, Shenk T, Levine AJ. The MDM2 Oncoprotein Binds Specifically to RNA through its RING Finger Domain Molecular Medicine. 2: 439-451. DOI: 10.1007/Bf03401903 |
0.332 |
|
1995 |
Lewis BA, Tullis G, Seto E, Horikoshi N, Weinmann R, Shenk T. Adenovirus E1A proteins interact with the cellular YY1 transcription factor Journal of Virology. 69: 1628-1636. PMID 7853498 DOI: 10.1128/Jvi.69.3.1628-1636.1995 |
0.363 |
|
1995 |
Horikoshi N, Usheva A, Chen J, Levine AJ, Weinmann R, Shenk T. Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression. Molecular and Cellular Biology. 15: 227-34. PMID 7799929 DOI: 10.1128/Mcb.15.1.227 |
0.31 |
|
1995 |
Dobbelstein M, Shenk T. In vitro selection of RNA ligands for the ribosomal L22 protein associated with Epstein-Barr virus-expressed RNA by using randomized and cDNA-derived RNA libraries Journal of Virology. 69: 8027-8034. PMID 7494316 DOI: 10.1128/Jvi.69.12.8027-8034.1995 |
0.318 |
|
1995 |
Zhu H, Shen Y, Shenk T. Human cytomegalovirus IE1 and IE2 proteins block apoptosis Journal of Virology. 69: 7960-7970. PMID 7494309 |
0.313 |
|
1994 |
Shen Y, Shenk T. Relief of p53-mediated transcriptional repression by the adenovirus E1B 19-kDa protein or the cellular Bcl-2 protein Proceedings of the National Academy of Sciences of the United States of America. 91: 8940-8944. PMID 8090749 DOI: 10.1073/Pnas.91.19.8940 |
0.337 |
|
1993 |
Kleinberger T, Shenk T. Adenovirus E4orf4 protein binds to protein phosphatase 2A, and the complex down regulates E1A-enhanced junB transcription Journal of Virology. 67: 7556-7560. PMID 8230475 DOI: 10.1128/Jvi.67.12.7556-7560.1993 |
0.344 |
|
1992 |
Takagaki Y, MacDonald CC, Shenk T, Manley JL. The human 64-kDa polyadenylylation factor contains a ribonucleoprotein-type RNA binding domain and unusual auxiliary motifs. Proceedings of the National Academy of Sciences of the United States of America. 89: 1403-7. PMID 1741396 DOI: 10.1073/Pnas.89.4.1403 |
0.308 |
|
1992 |
Hasson TB, Ornelles DA, Shenk T. Adenovirus L1 52- and 55-kilodalton proteins are present within assembling virions and colocalize with nuclear structures distinct from replication centers Journal of Virology. 66: 6133-6142. PMID 1527852 DOI: 10.1128/Jvi.66.10.6133-6142.1992 |
0.739 |
|
1992 |
Javier R, Raska K, Shenk T. Requirement for the adenovirus type 9 E4 region in production of mammary tumors Science. 257: 1267-1270. PMID 1519063 DOI: 10.1126/Science.1519063 |
0.307 |
|
1992 |
Toth M, Doerfler W, Shenk T. Adenovirus DNA replication facilitates binding of the MLTF/USF transcription factor to the viral major late promoter within infected cells Nucleic Acids Research. 20: 5143-5148. PMID 1408829 DOI: 10.1093/Nar/20.19.5143 |
0.623 |
|
1992 |
Müller U, Kleinberger T, Shenk T. Adenovirus E4orf4 protein reduces phosphorylation of c-Fos and E1A proteins while simultaneously reducing the level of AP-1 Journal of Virology. 66: 5867-5878. PMID 1326648 DOI: 10.1128/Jvi.66.10.5867-5878.1992 |
0.497 |
|
1991 |
Baim SB, Labow MA, Levine AJ, Shenk T. A chimeric mammalian transactivator based on the lac repressor that is regulated by temperature and isopropyl β-D-thiogalactopyranoside Proceedings of the National Academy of Sciences of the United States of America. 88: 5072-5076. PMID 2052587 DOI: 10.1073/pnas.88.12.5072 |
0.309 |
|
1991 |
Engel DA, Muller U, Gedrich RW, Eubanks JS, Shenk T. Induction of c-fos mRNA and AP-1 DNA-binding activity by cAMP in cooperation with either the adenovirus 243- or the adenovirus 289-amino acid E1A protein. Proceedings of the National Academy of Sciences of the United States of America. 88: 3957-61. PMID 1850843 |
0.304 |
|
1991 |
Shenk T, Flint J. Transcriptional and transforming activities of the adenovirus E1A proteins Advances in Cancer Research. 57: 47-85. PMID 1835254 DOI: 10.1016/S0065-230X(08)60995-1 |
0.444 |
|
1991 |
Schaack J, Logan J, Vakalopoulou E, Shenk T. Adenovirus E1A protein activates transcription of the E1A gene subsequent to transcription complex formation Journal of Virology. 65: 1687-1694. PMID 1825853 DOI: 10.1128/Jvi.65.4.1687-1694.1991 |
0.513 |
|
1991 |
Ornelles DA, Shenk T. Localization of the adenovirus early region 1B 55-kilodalton protein during lytic infection: Association with nuclear viral inclusions requires the early region 4 34-kilodalton protein Journal of Virology. 65: 424-439. PMID 1824641 |
0.431 |
|
1991 |
Montalvo EA, Shi Y, Shenk TE, Levine AJ. Negative regulation of the BZLF1 promoter of Epstein-Barr virus. Journal of Virology. 65: 3647-55. PMID 1645787 DOI: 10.1128/Jvi.65.7.3647-3655.1991 |
0.421 |
|
1990 |
Soloway PD, Shenk T. The adenovirus type 5 i-leader open reading frame functions in cis to reduce the half-life of L1 mRNAs. Journal of Virology. 64: 551-8. PMID 2296076 DOI: 10.1128/Jvi.64.2.551-558.1990 |
0.669 |
|
1990 |
Schaack J, Ho WYW, Freimuth P, Shenk T. Adenovirus terminal protein mediates both nuclear matrix association and efficient transcription of adenovirus DNA Genes and Development. 4: 1197-1208. PMID 2210375 DOI: 10.1101/Gad.4.7.1197 |
0.471 |
|
1990 |
Labow MA, Baim SB, Shenk T, Levine AJ. Conversion of the lac repressor into an allosterically regulated transcriptional activator for mammalian cells Molecular and Cellular Biology. 10: 3343-3356. PMID 2162473 DOI: 10.1128/mcb.10.7.3343-3356.1990 |
0.405 |
|
1990 |
Schaak J, Schedl P, Shenk T. Transcription of adenovirus and HeLa cell genes in the presence of drugs that inhibit topoisomerase I and II function. Nucleic Acids Research. 18: 1499-508. PMID 2158079 DOI: 10.1093/Nar/18.6.1499 |
0.376 |
|
1990 |
Chang LS, Shenk T. The adenovirus DNA-binding protein stimulates the rate of transcription directed by adenovirus and adeno-associated virus promoters Journal of Virology. 64: 2103-2109. PMID 2157873 DOI: 10.1128/Jvi.64.5.2103-2109.1990 |
0.456 |
|
1990 |
Schaack J, Schedl P, Shenk T. Topoisomerase I and II cleavage of adenovirus DNA in vivo: both topoisomerase activities appear to be required for adenovirus DNA replication. Journal of Virology. 64: 78-85. PMID 2152835 |
0.302 |
|
1990 |
Marton MJ, Baim SB, Ornelles DA, Shenk T. The adenovirus E4 17-kilodalton protein complexes with the cellular transcription factor E2F, altering its DNA-binding properties and stimulating E1A-independent accumulation of E2 mRNA Journal of Virology. 64: 2345-2359. PMID 2139141 DOI: 10.1128/Jvi.64.5.2345-2359.1990 |
0.374 |
|
1990 |
Takagaki Y, Manley JL, MacDonald CC, Wilusz J, Shenk T. A multisubunit factor, CstF, is required for polyadenylation of mammalian pre-mRNAs. Genes & Development. 4: 2112-20. PMID 1980119 DOI: 10.1101/Gad.4.12A.2112 |
0.316 |
|
1989 |
Schaack J, Shenk T. Adenovirus terminal protein mediates efficient and timely activation of viral transcription Current Topics in Microbiology and Immunology. 144: 185-190. PMID 2791638 DOI: 10.1007/978-3-642-74578-2_23 |
0.375 |
|
1989 |
Hasson TB, Soloway PD, Ornelles DA, Doerfler W, Shenk T. Adenovirus L1 52- and 55-kilodalton proteins are required for assembly of virions Journal of Virology. 63: 3612-3621. PMID 2760976 DOI: 10.1128/Jvi.63.9.3612-3621.1989 |
0.807 |
|
1989 |
Müller U, Roberts MP, Engel DA, Doerfler W, Shenk T. Induction of transcription factor AP-1 by adenovirus E1A protein and cAMP. Genes & Development. 3: 1991-2002. PMID 2559873 DOI: 10.1101/Gad.3.12A.1991 |
0.587 |
|
1989 |
Hardy S, Engel DA, Shenk T. An adenovirus early region 4 gene product is required for induction of the infection-specific form of cellular E2F activity. Genes & Development. 3: 1062-74. PMID 2550320 DOI: 10.1101/Gad.3.7.1062 |
0.427 |
|
1989 |
Samulski RJ, Chang LS, Shenk T. Helper-free stocks of recombinant adeno-associated viruses: Normal integration does not require viral gene expression Journal of Virology. 63: 3822-3828. PMID 2547998 DOI: 10.1128/Jvi.63.9.3822-3828.1989 |
0.612 |
|
1989 |
Chang LS, Shi Y, Shenk T. Adeno-associated virus P5 promoter contains an adenovirus E1A-inducible element and a binding site for the major late transcription factor Journal of Virology. 63: 3479-3488. PMID 2545917 DOI: 10.1128/Jvi.63.8.3479-3488.1989 |
0.341 |
|
1989 |
Wilus J, Pettine SM, Shenk T. Functional analysis of point mutations in the AAUAAA motif of the SV40 late polyadenylation signal Nucleic Acids Research. 17: 3899-3908. PMID 2543957 DOI: 10.1093/Nar/17.10.3899 |
0.307 |
|
1989 |
Flint J, Shenk T. Adenovirus E1A protein paradigm viral transactivator Annual Review of Genetics. 23: 141-161. PMID 2533472 DOI: 10.1146/Annurev.Ge.23.120189.001041 |
0.394 |
|
1989 |
Urbanelli D, Sawada Y, Raskova J, Jones NC, Shenk T, Raska K. C-terminal domain of the adenovirus E1A oncogene product is required for induction of cytotoxic T lymphocytes and tumor-specific transplantation immunity. Virology. 173: 607-14. PMID 2531954 DOI: 10.1016/0042-6822(89)90572-2 |
0.572 |
|
1989 |
Leppard KN, Shenk T. The adenovirus E1B 55 kd protein influences mRNA transport via an intranuclear effect on RNA metabolism Embo Journal. 8: 2329-2336. PMID 2529118 DOI: 10.1002/J.1460-2075.1989.Tb08360.X |
0.46 |
|
1989 |
Samulski RJ, Chang LS, Shenk T. Helper-free stocks of recombinant adeno-associated viruses: normal integration does not require viral gene expression. Journal of Virology. 63: 3822-3828. DOI: 10.1128/jvi.63.9.3822-3828.1989 |
0.544 |
|
1988 |
Moore MA, Shenk T. The adenovirus tripartite leader sequence can alter nuclear and cytoplasmic metabolism of a non-adenovirus mRNA within infected cells Nucleic Acids Research. 16: 2247-2262. PMID 3357776 DOI: 10.1093/Nar/16.5.2247 |
0.442 |
|
1988 |
Sawada Y, Raška K, Shenk T. Adenovirus type 5 and adenovirus type 12 recombinant viruses containing heterologous E1 Genes are viable, transform rat cells, but are not tumorigenic in rats Virology. 166: 281-284. PMID 2970715 DOI: 10.1016/0042-6822(88)90175-4 |
0.332 |
|
1988 |
Engel DA, Hardy S, Shenk T. cAMP acts in synergy with E1A protein to activate transcription of the adenovirus early genes E4 and E1A. Genes & Development. 2: 1517-28. PMID 2850966 |
0.362 |
|
1988 |
Wilusz J, Feig DI, Shenk T. The C proteins of heterogeneous nuclear ribonucleoprotein complexes interact with RNA sequences downstream of polyadenylation cleavage sites Molecular and Cellular Biology. 8: 4477-4483. PMID 2847033 DOI: 10.1128/Mcb.8.10.4477 |
0.365 |
|
1988 |
Hardy S, Shenk T. Adenoviral control regions activated by E1A and the cAMP response element bind to the same factor Proceedings of the National Academy of Sciences of the United States of America. 85: 4171-4175. PMID 2837758 DOI: 10.1073/Pnas.85.12.4171 |
0.328 |
|
1988 |
Wilusz J, Shenk T. A 64 kd nuclear protein binds to RNA segments that include the AAUAAA polyadenylation motif Cell. 52: 221-228. PMID 2830023 DOI: 10.1016/0092-8674(88)90510-7 |
0.357 |
|
1988 |
Samulski RJ, Shenk T. Adenovirus E1B 55-M(r) polypeptide facilitates timely cytoplasmic accumulation of adeno-associated virus mRNAs Journal of Virology. 62: 206-210. PMID 2824848 DOI: 10.1128/Jvi.62.1.206-210.1988 |
0.529 |
|
1988 |
Samulski RJ, Shenk T. Adenovirus E1B 55-Mr polypeptide facilitates timely cytoplasmic accumulation of adeno-associated virus mRNAs. Journal of Virology. 62: 206-210. DOI: 10.1128/jvi.62.1.206-210.1988 |
0.524 |
|
1987 |
Hearing P, Samulski RJ, Wishart WL, Shenk T. Identification of a repeated sequence element required for efficient encapsidation of the adenovirus type 5 chromosome Journal of Virology. 61: 2555-2558. PMID 3599182 DOI: 10.1128/Jvi.61.8.2555-2558.1987 |
0.529 |
|
1987 |
Logan J, Falck-Pedersen E, Darnell JE, Shenk T. A poly(A) addition site and a downstream termination region are required for efficient cessation of transcription by RNA polymerase II in the mouse beta maj-globin gene. Proceedings of the National Academy of Sciences of the United States of America. 84: 8306-10. PMID 3479794 DOI: 10.1073/Pnas.84.23.8306 |
0.333 |
|
1987 |
Moore M, Schaack J, Baim SB, Morimoto RI, Shenk T. Induced heat shock mRNAs escape the nucleocytoplasmic transport block in adenovirus-infected HeLa cells. Molecular and Cellular Biology. 7: 4505-12. PMID 3437895 DOI: 10.1128/mcb.7.12.4505-4512.1987 |
0.391 |
|
1987 |
Schneider RJ, Shenk T. Impact of virus infection on host cell protein synthesis Annual Review of Biochemistry. 56: 317-332. PMID 3113326 DOI: 10.1146/Annurev.Bi.56.070187.001533 |
0.469 |
|
1987 |
Samulski RJ, Chang LS, Shenk T. A recombinant plasmid from which an infectious adeno-associated virus genome can be excised in vitro and its use to study viral replication Journal of Virology. 61: 3096-3101. PMID 3041032 |
0.6 |
|
1987 |
Hearing P, Samulski RJ, Wishart WL, Shenk T. Identification of a repeated sequence element required for efficient encapsidation of the adenovirus type 5 chromosome. Journal of Virology. 61: 2555-2558. DOI: 10.1128/jvi.61.8.2555-2558.1987 |
0.412 |
|
1987 |
Samulski RJ, Chang LS, Shenk T. A recombinant plasmid from which an infectious adeno-associated virus genome can be excised in vitro and its use to study viral replication. Journal of Virology. 61: 3096-3101. DOI: 10.1128/jvi.61.10.3096-3101.1987 |
0.556 |
|
1986 |
Kitajewski J, Schneider RJ, Safer B, Shenk T. An adenovirus mutant unable to express VAI RNA displays different growth responses and sensitivity to interferon in various host cell lines Molecular and Cellular Biology. 6: 4493-4498. PMID 3796608 DOI: 10.1128/Mcb.6.12.4493 |
0.431 |
|
1986 |
Kitajewski J, Schneider RJ, Safer B, Munemitsu SM, Samuel CE, Thimmappaya B, Shenk T. Adenovirus VAI RNA antagonizes the antiviral action of interferon by preventing activation of the interferon-induced eIF-2α kinase Cell. 45: 195-200. PMID 3698097 DOI: 10.1016/0092-8674(86)90383-1 |
0.375 |
|
1986 |
Resnick J, Shenk T. Simian virus 40 agnoprotein facilitates normal nuclear location of the major capsid polypeptide and cell-to-cell spread of virus Journal of Virology. 60: 1098-1106. PMID 3023661 DOI: 10.1128/Jvi.60.3.1098-1106.1986 |
0.547 |
|
1986 |
Pilder S, Moore M, Logan J, Shenk T. The adenovirus E1B-55K transforming polypeptide modulates transport or cytoplasmic stabilization of viral and host cell mRNAs Molecular and Cellular Biology. 6: 470-476. PMID 2946932 DOI: 10.1128/Mcb.6.2.470 |
0.472 |
|
1986 |
Logan J, Shenk T. In vivo identification of sequence elements required for normal function of the adenovirus major late transcriptional control region Nucleic Acids Research. 14: 6327-6335. PMID 2944077 DOI: 10.1093/Nar/14.15.6327 |
0.349 |
|
1986 |
Hearing P, Shenk T. The adenovirus type 5 E1A enhancer contains two functionally distinct domains: One is specific for E1A and the other modulates all early units in cis Cell. 45: 229-236. PMID 2938742 DOI: 10.1016/0092-8674(86)90387-9 |
0.367 |
|
1985 |
Halbert DN, Cutt JR, Shenk T. Adenovirus early region 4 encodes functions required for efficient DNA replication, late gene expression, and host cell shutoff Journal of Virology. 56: 250-257. PMID 4032537 |
0.315 |
|
1985 |
Schneider RJ, Safer B, Munemitsu SM, Samuel CE, Shenk T. Adenovirus VAI RNA prevents phosphorylation of the eukaryotic initiation factor 2 alpha subunit subsequent to infection. Proceedings of the National Academy of Sciences of the United States of America. 82: 4321-5. PMID 2989814 DOI: 10.1073/Pnas.82.13.4321 |
0.411 |
|
1985 |
Hutchinson NI, Chang LS, Pater MM, Bouck N, Shenk TE, di Mayorca G. Characterization of a new simian virus 40 mutant, tsA3900, isolated from deletion mutant tsA1499. Journal of Virology. 53: 814-21. PMID 2983092 DOI: 10.1128/Jvi.53.3.814-821.1985 |
0.384 |
|
1985 |
Swimmer C, Shenk T. Selection of sequence elements that substitute for the standard AATAAA motif which signals 3′ processing and polyadenylation of late simian virus 40 mRNAs Nucleic Acids Research. 13: 8053-8063. PMID 2866490 DOI: 10.1093/Nar/13.22.8053 |
0.354 |
|
1985 |
Falck-Pedersen E, Logan J, Shenk T, Darnell JE. Transcription termination within the E1A gene of adenovirus induced by insertion of the mouse beta-major globin terminator element. Cell. 40: 897-905. PMID 2580640 DOI: 10.1016/0092-8674(85)90349-6 |
0.391 |
|
1984 |
Schneider RJ, Weinberger C, Shenk T. Adenovirus VAI RNA facilitates the initiation of translation in virus-infected cells Cell. 37: 291-298. PMID 6722874 DOI: 10.1016/0092-8674(84)90325-8 |
0.35 |
|
1984 |
Sarnow P, Hearing P, Anderson CW, Halbert DN, Shenk T, Levine AJ. Adenovirus early region 1B 58,000-dalton tumor antigen is physically associated with an early region 4 25,000-dalton protein in productively infected cells. Journal of Virology. 49: 692-700. PMID 6699935 DOI: 10.1128/Jvi.49.3.692-700.1984 |
0.37 |
|
1984 |
Pilder S, Logan J, Shenk T. Deletion of the gene encoding the adenovirus 5 early region 1B 21,000-molecular-weight polypeptide leads to degradation of viral and host cell DNA Journal of Virology. 52: 664-671. PMID 6492257 |
0.334 |
|
1984 |
Swimmer C, Shenk T. A viable simian virus 40 variant that carries a newly generated sequence reiteration in place of the normal duplicated enhancer element Proceedings of the National Academy of Sciences of the United States of America. 81: 6652-6656. PMID 6093109 DOI: 10.1073/Pnas.81.21.6652 |
0.478 |
|
1982 |
Colby WW, Shenk T. Fragments of the simian virus 40 transforming gene facilitate transformation of rat embryo cells. Proceedings of the National Academy of Sciences of the United States of America. 79: 5189-93. PMID 6291029 DOI: 10.1073/Pnas.79.17.5189 |
0.374 |
|
1980 |
Ross SR, Levine AJ, Galos RS, Williams J, Shenk T. Early viral proteins in HeLa cells infected with adenovirus type 5 host range mutants. Virology. 103: 475-92. PMID 7385588 |
0.401 |
|
1980 |
Galos RS, Williams J, Shenk T, Jones N. Physical location of host-range mutations of adenovirus type 5; Deletion and marker-rescue mapping Virology. 104: 510-513. PMID 6994340 DOI: 10.1016/0042-6822(80)90356-6 |
0.482 |
|
1980 |
Shenk T, Jones N, Colby W, Fowlkes D. Functional analysis of adenovirus-5 host-range deletion mutants defective for transformation of rat embryo cells. Cold Spring Harbor Symposia On Quantitative Biology. 44: 367-75. PMID 6933036 DOI: 10.1101/Sqb.1980.044.01.041 |
0.559 |
|
1980 |
Dhruva BR, Shenk T, Subramanian KN. Integration in vivo into simian virus 40 DNA of a sequence that resembles a certain family of genomic interspersed repeated sequences Proceedings of the National Academy of Sciences of the United States of America. 77: 4514-4518. PMID 6254029 DOI: 10.1073/Pnas.77.8.4514 |
0.337 |
|
1979 |
Thimmappaya B, Jones N, Shenk T. A mutation which alters initiation of transcription by RNA polymerase III on the Ad5 chromosome Cell. 18: 947-954. PMID 519773 DOI: 10.1016/0092-8674(79)90207-1 |
0.557 |
|
1979 |
Jones N, Shenk T. Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells Cell. 17: 683-689. PMID 476833 DOI: 10.1016/0092-8674(79)90275-7 |
0.574 |
|
1979 |
Jones N, Shenk T. An adenovirus type 5 early gene function regulates expression of other early viral genes Proceedings of the National Academy of Sciences of the United States of America. 76: 3665-3669. PMID 291030 |
0.636 |
|
1979 |
Thimmappaya B, Shenk T. Nucleotide sequence analysis of viable deletion mutants lacking segments of the Simian virus 40 genome coding for small t antigen Journal of Virology. 30: 668-673. PMID 225535 DOI: 10.1128/Jvi.30.3.668-673.1979 |
0.368 |
|
1978 |
Jones N, Shenk T. Isolation of deletion and substitution mutants of adenovirus type 5 Cell. 13: 181-188. PMID 620421 DOI: 10.1016/0092-8674(78)90148-4 |
0.531 |
|
1978 |
Bouck N, Beales N, Shenk T, Berg P, di Mayorca G. New region of the simian virus 40 genome required for efficient viral transformation. Proceedings of the National Academy of Sciences of the United States of America. 75: 2473-7. PMID 209467 DOI: 10.1073/Pnas.75.5.2473 |
0.582 |
|
1977 |
Schlesinger RW, Stollar V, Guild GM, Igarashi A, Shenk TE, Peleg J. The significance and nature of defective interfering viruses. Bulletin Der Schweizerischen Akademie Der Medizinischen Wissenschaften. 33: 229-42. PMID 912148 |
0.65 |
|
1976 |
Shenk TE, Berg P. Isolation and propagation of a segment of the simian virus 40 genome containing the origin of DNA replication. Proceedings of the National Academy of Sciences of the United States of America. 73: 1513-7. PMID 179089 DOI: 10.1073/Pnas.73.5.1513 |
0.51 |
|
1976 |
Shenk TE, Carbon J, Berg P. Construction and analysis of viable deletion mutants of simian virus 40. Journal of Virology. 18: 664-71. PMID 178902 DOI: 10.1128/Jvi.18.2.664-671.1976 |
0.499 |
|
1975 |
Stollar V, Shenk TE, Koo R, Igarashi A, Schlesinger RW. Observations of Aedes albopictus cell cultures persistently infected with Sindbis virus. Annals of the New York Academy of Sciences. 266: 214-31. PMID 1072595 DOI: 10.1111/J.1749-6632.1975.Tb35103.X |
0.653 |
|
1975 |
Carbon J, Shenk TE, Berg P. Construction in vitro of mutants of simian virus 40: insertion of a poly(dA-dT) segment at the Hemophilus parainfluenza II restriction endonuclease cleavage site. Journal of Molecular Biology. 98: 1-15. PMID 172641 DOI: 10.1016/S0022-2836(75)80097-0 |
0.481 |
|
1975 |
Shenk TE, Rhodes C, Rigby PW, Berg P. Mapping of mutational alterations in DNA with S1 nuclease: the location of deletions, insertions and temperature-sensitive mutations in SV40. Cold Spring Harbor Symposia On Quantitative Biology. 39: 61-7. PMID 169094 DOI: 10.1101/Sqb.1974.039.01.011 |
0.383 |
|
1975 |
Carbon J, Shenk TE, Berg P. Biochemical procedure for production of small deletions in simian virus 40 DNA. Proceedings of the National Academy of Sciences of the United States of America. 72: 1392-6. PMID 165505 DOI: 10.1073/Pnas.72.4.1392 |
0.557 |
|
1975 |
Shenk TE, Rhodes C, Rigby PW, Berg P. Biochemical method for mapping mutational alterations in DNA with S1 nuclease: the location of deletions and temperature-sensitive mutations in simian virus 40. Proceedings of the National Academy of Sciences of the United States of America. 72: 989-93. PMID 165498 DOI: 10.1073/Pnas.72.3.989 |
0.518 |
|
1974 |
Shenk TE, Koshelnyk KA, Stollar V. Temperature-sensitive virus from Aedes albopictus cells chronically infected with Sindbis virus. Journal of Virology. 13: 439-47. PMID 4855741 DOI: 10.1128/Jvi.13.2.439-447.1974 |
0.67 |
|
1973 |
Shenk TE, Stollar V. Defective-interfering particles of Sindbis virus. II. Homologous interference. Virology. 55: 530-4. PMID 4795463 DOI: 10.1016/0042-6822(73)90197-9 |
0.629 |
|
1973 |
Shenk TE, Stollar V. Defective-interfering particles of Sindbis virus. I. Isolation and some chemical and biological properties. Virology. 53: 162-73. PMID 4735935 DOI: 10.1016/0042-6822(73)90475-3 |
0.626 |
|
1973 |
Stollar V, Shenk TE. Homologous viral interference in Aedes albopictus cultures chronically infected with Sindbis virus. Journal of Virology. 11: 592-5. PMID 4735592 DOI: 10.1128/Jvi.11.4.592-595.1973 |
0.697 |
|
1973 |
Huth W, Paul H, Querfurth G, Lesemann DE, Hull R, Plaskitt A, Gilden RV, Frank K, Hanson M, Bladen S, Toni R, Oroszlan S, Gendrault J, Steffan A, Kirn A, ... ... Shenk TE, et al. Subject Index, Vol. 2, 1973-74 Intervirology. 2: 371-375. DOI: 10.1159/000149446 |
0.525 |
|
1973 |
Stollar V, Peleg J, Shenk TE. Temperature sensitivity of a sindbis virus mutant isolated from persistently infected Aedes aegypti cell culture Intervirology. 2: 337-344. DOI: 10.1159/000149441 |
0.693 |
|
1973 |
Huth W, Paul H, Querfurth G, Lesemann DE, Hull R, Plaskitt A, Gilden RV, Frank K, Hanson M, Bladen S, Toni R, Oroszlan S, Gendrault J, Steffan A, Kirn A, ... ... Shenk TE, et al. Contents, Vol. 2, 1973-74 Intervirology. 2. DOI: 10.1159/000149434 |
0.533 |
|
1972 |
Shenk TE, Stollar V. Viral RNA species in BHK-21 cells infected with Sindbis virus serially passaged at high multiplicity of infection. Biochemical and Biophysical Research Communications. 49: 60-7. PMID 4672930 DOI: 10.1016/0006-291X(72)90009-5 |
0.659 |
|
1972 |
Shenk TE, Stollar V. Effect of double-stranded RNAs from Sindbis virus-infected cells on rabbit reticulocyte and chick embryo cell-free protein synthesis. Biochimica Et Biophysica Acta. 287: 501-13. PMID 4641255 DOI: 10.1016/0005-2787(72)90295-X |
0.632 |
|
1972 |
Stollar V, Shenk TE, Stollar BD. Double-stranded RNA in hamster, chick, and mosquito cells infected with Sindbis virus. Virology. 47: 122-32. PMID 4550788 DOI: 10.1016/0042-6822(72)90245-0 |
0.61 |
|
1971 |
Stollar V, Stevens TM, Shenk T. 3. RNA of uninfected and Sindbis virus-infected Aedes albopictus cells Current Topics in Microbiology and Immunology. 55: 164-169. PMID 5142328 DOI: 10.1007/978-3-642-65224-0_28 |
0.698 |
|
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