Derek Yung-Ho Chiang - Publications

Affiliations: 
2005 University of California, Berkeley, Berkeley, CA, United States 

89 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Kang B, Camps J, Fan B, Jiang H, Ibrahim MM, Hu X, Qin S, Kirchhoff D, Chiang DY, Wang S, Ye Y, Shen Z, Bu Z, Zhang Z, Roider HG. Parallel single-cell and bulk transcriptome analyses reveal key features of the gastric tumor microenvironment. Genome Biology. 23: 265. PMID 36550535 DOI: 10.1186/s13059-022-02828-2  0.583
2021 Georgiev P, Muise ES, Linn DE, Hinton MC, Wang Y, Cai M, Cadzow L, Wilson DC, Sukumar S, Caniga M, Chen L, Xiao H, Yearley JH, Sriram V, Nebozhyn M, ... Chiang DY, et al. Reverse Translating Molecular Determinants of Anti-Programmed Death 1 Immunotherapy Response in Mouse Syngeneic Tumor Models. Molecular Cancer Therapeutics. PMID 34965960 DOI: 10.1158/1535-7163.MCT-21-0561  0.591
2020 Singh L, Muise ES, Bhattacharya A, Grein J, Javaid S, Stivers P, Zhang J, Qu Y, Joyce-Shaikh B, Loboda A, Zhang C, Meehl M, Chiang DY, Ranganath SH, Rosenzweig M, et al. ILT3 (LILRB4) Promotes the Immunosuppressive Function of Tumor-Educated Human Monocytic Myeloid-Derived Suppressor Cells. Molecular Cancer Research : McR. PMID 33372059 DOI: 10.1158/1541-7786.MCR-20-0622  0.583
2019 Boyle TA, Quinn GP, Schabath MB, Muñoz-Antonia T, Saller JJ, Duarte LF, Hair LS, Teer JK, Chiang DY, Leary R, Wong CC, Savchenko A, Singh AP, Charette L, Mendell K, et al. A community-based lung cancer rapid tissue donation protocol provides high-quality drug-resistant specimens for proteogenomic analyses. Cancer Medicine. PMID 31747139 DOI: 10.1002/Cam4.2670  0.617
2018 Yap YS, Singh AP, Lim JHC, Ahn JH, Jung KH, Kim J, Dent RA, Ng RCH, Kim SB, Chiang DY. Elucidating therapeutic molecular targets in premenopausal Asian women with recurrent breast cancers. Npj Breast Cancer. 4: 19. PMID 30062102 DOI: 10.1016/S0959-8049(18)30653-1  0.652
2017 Zhang L, MacIsaac KD, Zhou T, Huang PY, Xin C, Dobson JR, Yu K, Chiang DY, Fan Y, Pelletier MR, Wang Y, Jaeger S, Krishnamurthy Radhakrishna V, JeBailey L, Skewes-Cox P, et al. Genomic Analysis of Nasopharyngeal Carcinoma Reveals TME-based Subtypes. Molecular Cancer Research : McR. PMID 28851814 DOI: 10.1158/1541-7786.Mcr-17-0134  0.681
2017 Chiang DY, Villanueva A. Progress towards molecular patient stratification of hepatocellular carcinoma: lost in translation? Journal of Hepatology. PMID 28837834 DOI: 10.1016/J.Jhep.2017.07.031  0.623
2016 Riester M, Singh AP, Brannon AR, Yu K, Campbell CD, Chiang DY, Morrissey MP. PureCN: copy number calling and SNV classification using targeted short read sequencing. Source Code For Biology and Medicine. 11: 13. PMID 27999612 DOI: 10.1186/S13029-016-0060-Z  0.65
2016 Zhu AX, Chen D, He W, Kanai M, Voi M, Chen LT, Daniele B, Furuse J, Kang YK, Poon RT, Vogel A, Chiang DY. Integrative Biomarker Analyses Indicate Etiological Variations in Hepatocellular Carcinoma. Journal of Hepatology. PMID 27130844 DOI: 10.1016/J.Jhep.2016.04.015  0.623
2016 Veloso A, Cao ZA, Chiang DY, Bitter H, MacIsaac KD. Abstract 854: Mutation load measured using a 315 gene panel predicts genome-wide mutation load Cancer Research. 76: 854-854. DOI: 10.1158/1538-7445.Am2016-854  0.647
2015 Gao H, Korn JM, Ferretti S, Monahan JE, Wang Y, Singh M, Zhang C, Schnell C, Yang G, Zhang Y, Balbin OA, Barbe S, Cai H, Casey F, Chatterjee S, Chiang DY, et al. High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response. Nature Medicine. PMID 26479923 DOI: 10.1038/Nm.3954  0.689
2015 Glasscock E, Voigt N, McCauley MD, Sun Q, Li N, Chiang DY, Zhou XB, Molina CE, Thomas D, Schmidt C, Skapura DG, Noebels JL, Dobrev D, Wehrens XH. Expression and function of Kv1.1 potassium channels in human atria from patients with atrial fibrillation. Basic Research in Cardiology. 110: 505. PMID 26162324 DOI: 10.1007/S00395-015-0505-6  0.556
2015 Chiang DY, Kim JJ, Valdes SO, de la Uz C, Fan Y, Orcutt J, Domino M, Smith M, Wehrens XH, Miyake CY. Loss-of-Function SCN5A Mutations Associated with Sinus Node Dysfunction, Atrial Arrhythmias, and Poor Pacemaker Capture. Circulation. Arrhythmia and Electrophysiology. PMID 26111534 DOI: 10.1161/CIRCEP.115.003098  0.557
2015 Bhang HE, Ruddy DA, Krishnamurthy Radhakrishna V, Caushi JX, Zhao R, Hims MM, Singh AP, Kao I, Rakiec D, Shaw P, Balak M, Raza A, Ackley E, Keen N, Schlabach MR, ... Chiang DY, et al. Studying clonal dynamics in response to cancer therapy using high-complexity barcoding. Nature Medicine. 21: 440-8. PMID 25849130 DOI: 10.1038/Nm.3841  0.692
2015 Sendor AB, Hacker KE, Chen S, Corona AL, Sen O, Chiang DY, Snavely A, Rogers AB, Montgomery SA, Rathmell WK, McRee AJ. Von Hippel-Lindau status influences phenotype of liver cancers arising from PTEN loss. Gastrointestinal Cancer : Targets and Therapy. 5: 61-71. PMID 25844041 DOI: 10.2147/GICTT.S72274  0.57
2015 Huang TJ, Chiang DY, Shih C, Lee CC, Mao CW, Wang BC. Promoted decomposition of NOx in automotive diesel-like exhausts by electro-catalytic honeycombs. Environmental Science & Technology. 49: 3711-7. PMID 25719390 DOI: 10.1021/acs.est.5b00226  0.525
2015 Chiang DY, Zhang M, Voigt N, Alsina KM, Jakob H, Martin JF, Dobrev D, Wehrens XH, Li N. Identification of microRNA-mRNA dysregulations in paroxysmal atrial fibrillation. International Journal of Cardiology. 184: 190-7. PMID 25706326 DOI: 10.1016/j.ijcard.2015.01.075  0.55
2015 Chiang DY, Lebesgue N, Beavers DL, Alsina KM, Damen JM, Voigt N, Dobrev D, Wehrens XH, Scholten A. Alterations in the interactome of serine/threonine protein phosphatase type-1 in atrial fibrillation patients. Journal of the American College of Cardiology. 65: 163-73. PMID 25593058 DOI: 10.1016/j.jacc.2014.10.042  0.553
2015 Yang X, Wang T, Lin X, Yue X, Wang Q, Wang G, Fu Q, Ai X, Chiang DY, Miyake CY, Wehrens XH, Chang J. Genetic deletion of Rnd3/RhoE results in mouse heart calcium leakage through upregulation of protein kinase A signaling. Circulation Research. 116: e1-e10. PMID 25348166 DOI: 10.1161/CIRCRESAHA.116.304940  0.562
2015 Chiang DY, Huang A. Co-expression networks identify distinct immune infiltrates in hepatocellular carcinoma Journal For Immunotherapy of Cancer. 3. DOI: 10.1186/2051-1426-3-S2-P213  0.629
2015 Balbin A, Singh A, Korn J, Gao H, Stuart D, Green J, Crenshaw A, Mahan S, Houde N, Raza A, Leary R, Chiang D, Morrissey M, Winckler W, William S. Abstract B36: Modeling genetic mechanisms of resistance in melanoma primary tumor xenografts Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Pms14-B36  0.648
2015 Solovieff N, Hims M, Leary R, Chiang D, Germa C, Massacesi C, Hirawat S, Scherer SJ, Morrissey M, Winckler W, Tomaso Ed. Abstract LB-A05: Profiling cell free DNA in breast cancer and non-small cell lung cancer using broad NGS assessment Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-Lb-A05  0.657
2015 Villanueva A, Hoshida Y, Chiang DY, Llovet JM. Hepatocellular carcinoma Molecular Oncology: Causes of Cancer and Targets For Treatment. 569-578. DOI: 10.1017/CBO9781139046947.050  0.576
2014 Chiang DY, Kongchan N, Beavers DL, Alsina KM, Voigt N, Neilson JR, Jakob H, Martin JF, Dobrev D, Wehrens XH, Li N. Loss of microRNA-106b-25 cluster promotes atrial fibrillation by enhancing ryanodine receptor type-2 expression and calcium release. Circulation. Arrhythmia and Electrophysiology. 7: 1214-22. PMID 25389315 DOI: 10.1161/Circep.114.001973  0.553
2014 Beavers DL, Landstrom AP, Chiang DY, Wehrens XH. Emerging roles of junctophilin-2 in the heart and implications for cardiac diseases. Cardiovascular Research. 103: 198-205. PMID 24935431 DOI: 10.1093/cvr/cvu151  0.553
2014 Chiang DY, Li N, Wang Q, Alsina KM, Quick AP, Reynolds JO, Wang G, Skapura D, Voigt N, Dobrev D, Wehrens XH. Impaired local regulation of ryanodine receptor type 2 by protein phosphatase 1 promotes atrial fibrillation. Cardiovascular Research. 103: 178-87. PMID 24812280 DOI: 10.1093/cvr/cvu123  0.559
2014 Jeck WR, Parker J, Carson CC, Shields JM, Sambade MJ, Peters EC, Burd CE, Thomas NE, Chiang DY, Liu W, Eberhard DA, Ollila D, Grilley-Olson J, Moschos S, Neil Hayes D, et al. Targeted next generation sequencing identifies clinically actionable mutations in patients with melanoma. Pigment Cell & Melanoma Research. 27: 653-63. PMID 24628946 DOI: 10.1111/Pcmr.12238  0.665
2014 Grassian AR, Pagliarini R, Chiang DY. Mutations of isocitrate dehydrogenase 1 and 2 in intrahepatic cholangiocarcinoma. Current Opinion in Gastroenterology. 30: 295-302. PMID 24569570 DOI: 10.1097/Mog.0000000000000050  0.633
2014 Li N, Chiang DY, Wang S, Wang Q, Sun L, Voigt N, Respress JL, Ather S, Skapura DG, Jordan VK, Horrigan FT, Schmitz W, Müller FU, Valderrabano M, Nattel S, et al. Ryanodine receptor-mediated calcium leak drives progressive development of an atrial fibrillation substrate in a transgenic mouse model. Circulation. 129: 1276-85. PMID 24398018 DOI: 10.1161/Circulationaha.113.006611  0.556
2014 Voigt N, Heijman J, Wang Q, Chiang DY, Li N, Karck M, Wehrens XH, Nattel S, Dobrev D. Cellular and molecular mechanisms of atrial arrhythmogenesis in patients with paroxysmal atrial fibrillation. Circulation. 129: 145-56. PMID 24249718 DOI: 10.1161/Circulationaha.113.006641  0.536
2014 Shi W, Chin C, Tang T, Hipolito L, Srinivasan P, Chiang D, Peng D, Tomaso ED, Tangri S, Lameh J, Pollner R. Abstract 1892: Development of a clinical targeted next generation sequencing test for challenging formalin-fixed paraffin-embedded (FFPE) cancer samples Cancer Research. 74: 1892-1892. DOI: 10.1158/1538-7445.Am2014-1892  0.649
2013 Chiang DY, Cuthbertson DW, Ruiz FR, Li N, Pereira FA. A coregulatory network of NR2F1 and microRNA-140. Plos One. 8: e83358. PMID 24349493 DOI: 10.1371/journal.pone.0083358  0.539
2013 Cleary SP, Jeck WR, Zhao X, Chen K, Selitsky SR, Savich GL, Tan TX, Wu MC, Getz G, Lawrence MS, Parker JS, Li J, Powers S, Kim H, Fischer S, ... Chiang DY, et al. Identification of driver genes in hepatocellular carcinoma by exome sequencing. Hepatology (Baltimore, Md.). 58: 1693-702. PMID 23728943 DOI: 10.1002/Hep.26540  0.674
2013 Reynolds JO, Chiang DY, Wang W, Beavers DL, Dixit SS, Skapura DG, Landstrom AP, Song LS, Ackerman MJ, Wehrens XH. Junctophilin-2 is necessary for T-tubule maturation during mouse heart development. Cardiovascular Research. 100: 44-53. PMID 23715556 DOI: 10.1093/cvr/cvt133  0.549
2013 Wehrens XH, Chiang DY, Li N. Chronic exercise: a contributing factor to atrial fibrillation? Journal of the American College of Cardiology. 62: 78-80. PMID 23583764 DOI: 10.1016/j.jacc.2013.02.070  0.529
2013 Dixit SS, Wang T, Manzano EJ, Yoo S, Lee J, Chiang DY, Ryan N, Respress JL, Yechoor VK, Wehrens XH. Effects of CaMKII-mediated phosphorylation of ryanodine receptor type 2 on islet calcium handling, insulin secretion, and glucose tolerance. Plos One. 8: e58655. PMID 23516528 DOI: 10.1371/journal.pone.0058655  0.542
2013 Huang Y, Hu Y, Jones CD, MacLeod JN, Chiang DY, Liu Y, Prins JF, Liu J. A robust method for transcript quantification with RNA-seq data. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 20: 167-87. PMID 23461570 DOI: 10.1089/Cmb.2012.0230  0.639
2013 Mezlini AM, Smith EJ, Fiume M, Buske O, Savich GL, Shah S, Aparicio S, Chiang DY, Goldenberg A, Brudno M. iReckon: simultaneous isoform discovery and abundance estimation from RNA-seq data. Genome Research. 23: 519-29. PMID 23204306 DOI: 10.1101/Gr.142232.112  0.637
2013 Hu Y, Huang Y, Du Y, Orellana CF, Singh D, Johnson AR, Monroy A, Kuan PF, Hammond SM, Makowski L, Randell SH, Chiang DY, Hayes DN, Jones C, Liu Y, et al. DiffSplice: the genome-wide detection of differential splicing events with RNA-seq. Nucleic Acids Research. 41: e39. PMID 23155066 DOI: 10.1093/nar/gks1026  0.652
2013 Wang P, Dong Q, Zhang C, Kuan PF, Liu Y, Jeck WR, Andersen JB, Jiang W, Savich GL, Tan TX, Auman JT, Hoskins JM, Misher AD, Moser CD, Yourstone SM, ... Chiang DY, et al. Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas. Oncogene. 32: 3091-100. PMID 22824796 DOI: 10.1038/Onc.2012.315  0.643
2013 Cleary SP, Jeck WR, Zhao X, Selitsky SR, Savich GL, Tan T, Wu MC, Getz G, Lawrence MS, Parker JS, Li J, Powers S, Kim H, Fischer SE, Guindi M, ... Chiang DY, et al. Abstract 4598: Identification of driver genes in hepatocellular carcinoma by exome sequencing. Cancer Research. 73: 4598-4598. DOI: 10.1158/1538-7445.Am2013-4598  0.678
2012 Kuan PF, Chiang DY. Integrating prior knowledge in multiple testing under dependence with applications to detecting differential DNA methylation. Biometrics. 68: 774-83. PMID 22260651 DOI: 10.1111/J.1541-0420.2011.01730.X  0.605
2012 Wang P, Dong Q, Zhang C, Kuan P, Liu Y, Jeck WR, Andersen JB, Auman JT, Hoskins JM, Kim JW, Cibulskis K, Getz G, Hunt HV, Thorgeirsson SS, Roberts LR, ... Chiang DY, et al. Abstract 1058: Mutations in isocitrate dehydrogenase 1 and 2 are associated with DNA hypermethylation in intrahepatic cholangiocarcinomas Cancer Research. 72: 1058-1058. DOI: 10.1158/1538-7445.Am2012-1058  0.664
2011 Ou SL, Kuo PC, Ma SH, Shen CL, Tsai TL, Chen SC, Chiang DY, Lee CT. Crystallization mechanisms of phase change (GeSbSn)(100-x)Co(x) optical recording films. Journal of Nanoscience and Nanotechnology. 11: 11138-41. PMID 22409072  0.52
2011 Ou SL, Kuo PC, Sheu SC, Shen CL, Tsai TL, Chen SC, Chiang DY. Microstructure and crystallization kinetics analysis of the (In15Sb85)(100-x)Zn(x) phase change recording thin films. Journal of Nanoscience and Nanotechnology. 11: 10922-5. PMID 22409026  0.522
2011 Cho J, Pastorino S, Zeng Q, Xu X, Johnson W, Vandenberg S, Verhaak R, Cherniack AD, Watanabe H, Dutt A, Kwon J, Chao YS, Onofrio RC, Chiang D, Yuza Y, et al. Glioblastoma-derived epidermal growth factor receptor carboxyl-terminal deletion mutants are transforming and are sensitive to EGFR-directed therapies. Cancer Research. 71: 7587-96. PMID 22001862 DOI: 10.1158/0008-5472.Can-11-0821  0.623
2011 Bass AJ, Lawrence MS, Brace LE, Ramos AH, Drier Y, Cibulskis K, Sougnez C, Voet D, Saksena G, Sivachenko A, Jing R, Parkin M, Pugh T, Verhaak RG, Stransky N, ... Chiang DY, et al. Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion. Nature Genetics. 43: 964-8. PMID 21892161 DOI: 10.1038/Ng.936  0.803
2011 Singh D, Orellana CF, Hu Y, Jones CD, Liu Y, Chiang DY, Liu J, Prins JF. FDM: a graph-based statistical method to detect differential transcription using RNA-seq data. Bioinformatics (Oxford, England). 27: 2633-40. PMID 21824971 DOI: 10.1093/Bioinformatics/Btr458  0.647
2011 Dooley AL, Winslow MM, Chiang DY, Banerji S, Stransky N, Dayton TL, Snyder EL, Senna S, Whittaker CA, Bronson RT, Crowley D, Barretina J, Garraway L, Meyerson M, Jacks T. Nuclear factor I/B is an oncogene in small cell lung cancer. Genes & Development. 25: 1470-5. PMID 21764851 DOI: 10.1101/Gad.2046711  0.788
2011 Winslow MM, Dayton TL, Verhaak RG, Kim-Kiselak C, Snyder EL, Feldser DM, Hubbard DD, DuPage MJ, Whittaker CA, Hoersch S, Yoon S, Crowley D, Bronson RT, Chiang DY, Meyerson M, et al. Suppression of lung adenocarcinoma progression by Nkx2-1. Nature. 473: 101-4. PMID 21471965 DOI: 10.1038/Nature09881  0.654
2011 Toffanin S, Hoshida Y, Lachenmayer A, Villanueva A, Cabellos L, Minguez B, Savic R, Ward SC, Thung S, Chiang DY, Alsinet C, Tovar V, Roayaie S, Schwartz M, Bruix J, et al. MicroRNA-based classification of hepatocellular carcinoma and oncogenic role of miR-517a. Gastroenterology. 140: 1618-28.e16. PMID 21324318 DOI: 10.1053/J.Gastro.2011.02.009  0.634
2010 Wang K, Singh D, Zeng Z, Coleman SJ, Huang Y, Savich GL, He X, Mieczkowski P, Grimm SA, Perou CM, MacLeod JN, Chiang DY, Prins JF, Liu J. MapSplice: accurate mapping of RNA-seq reads for splice junction discovery. Nucleic Acids Research. 38: e178. PMID 20802226 DOI: 10.1093/Nar/Gkq622  0.616
2010 Barretina J, Taylor BS, Banerji S, Ramos AH, Lagos-Quintana M, Decarolis PL, Shah K, Socci ND, Weir BA, Ho A, Chiang DY, Reva B, Mermel CH, Getz G, Antipin Y, et al. Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy. Nature Genetics. 42: 715-21. PMID 20601955 DOI: 10.1038/Ng.619  0.795
2010 Hu Y, Wang K, He X, Chiang DY, Prins JF, Liu J. A probabilistic framework for aligning paired-end RNA-seq data. Bioinformatics (Oxford, England). 26: 1950-7. PMID 20576625 DOI: 10.1093/Bioinformatics/Btq336  0.616
2010 Zender L, Villanueva A, Tovar V, Sia D, Chiang DY, Llovet JM. Cancer gene discovery in hepatocellular carcinoma. Journal of Hepatology. 52: 921-9. PMID 20385424 DOI: 10.1016/J.Jhep.2009.12.034  0.676
2010 Tovar V, Alsinet C, Villanueva A, Hoshida Y, Chiang DY, Solé M, Thung S, Moyano S, Toffanin S, Mínguez B, Cabellos L, Peix J, Schwartz M, Mazzaferro V, Bruix J, et al. IGF activation in a molecular subclass of hepatocellular carcinoma and pre-clinical efficacy of IGF-1R blockage. Journal of Hepatology. 52: 550-9. PMID 20206398 DOI: 10.1016/J.Jhep.2010.01.015  0.631
2010 Beroukhim R, Mermel CH, Porter D, Wei G, Raychaudhuri S, Donovan J, Barretina J, Boehm JS, Dobson J, Urashima M, Mc Henry KT, Pinchback RM, Ligon AH, Cho YJ, Haery L, ... Chiang DY, et al. The landscape of somatic copy-number alteration across human cancers. Nature. 463: 899-905. PMID 20164920 DOI: 10.1038/Nature08822  0.783
2010 Tovar V, Alsinet C, Villanueva A, Hoshida Y, Chiang DY, Solé M, Thung S, Moyano S, Toffanin S, Minguez B, Cabellos L, Peix J, Schwartz M, Mazzaferro V, Bruix J, et al. Abstract LB-233: IGF activation in a molecular subclass of hepatocellular carcinoma and preclinical efficacy of IGF-1R blockage Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-233  0.647
2010 Dooley AL, Winslow MM, Chiang D, Banerji S, Whittaker C, Bronson R, Crowley D, Meyerson M, Jacks T. Abstract LB-146: Identification of copy number alterations in small cell lung cancer Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-146  0.675
2010 Toffanin S, Hoshida Y, Lachenmayer A, Cabellos L, Lu J, Villanueva A, Minguez B, Savic R, Chiang DY, Roayaie S, Bruix J, Schwartz ME, Mazzaferro V, Waxman S, Friedman SL, et al. Abstract 2996: Overexpression of potential oncogenic microRNAs defines a new molecular subclass of hepatocellular carcinoma Cancer Research. 70: 2996-2996. DOI: 10.1158/1538-7445.Am10-2996  0.638
2009 Chiang DY, McCarroll SA. Mapping duplicated sequences. Nature Biotechnology. 27: 1001-2. PMID 19898454 DOI: 10.1038/Nbt1109-1001  0.607
2009 Hoshida Y, Nijman SM, Kobayashi M, Chan JA, Brunet JP, Chiang DY, Villanueva A, Newell P, Ikeda K, Hashimoto M, Watanabe G, Gabriel S, Friedman SL, Kumada H, Llovet JM, et al. Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma. Cancer Research. 69: 7385-92. PMID 19723656 DOI: 10.1158/0008-5472.Can-09-1089  0.66
2009 Newell P, Toffanin S, Villanueva A, Chiang DY, Minguez B, Cabellos L, Savic R, Hoshida Y, Lim KH, Melgar-Lesmes P, Yea S, Peix J, Deniz K, Fiel MI, Thung S, et al. Ras pathway activation in hepatocellular carcinoma and anti-tumoral effect of combined sorafenib and rapamycin in vivo. Journal of Hepatology. 51: 725-33. PMID 19665249 DOI: 10.1016/J.Jhep.2009.03.028  0.626
2009 Sos ML, Michel K, Zander T, Weiss J, Frommolt P, Peifer M, Li D, Ullrich R, Koker M, Fischer F, Shimamura T, Rauh D, Mermel C, Fischer S, Stückrath I, ... Chiang D, et al. Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions. The Journal of Clinical Investigation. 119: 1727-40. PMID 19451690 DOI: 10.1172/Jci37127  0.792
2009 Mínguez B, Tovar V, Chiang D, Villanueva A, Llovet JM. Pathogenesis of hepatocellular carcinoma and molecular therapies. Current Opinion in Gastroenterology. 25: 186-94. PMID 19387255 DOI: 10.1097/Mog.0B013E32832962A1  0.663
2009 Keng VW, Villanueva A, Chiang DY, Dupuy AJ, Ryan BJ, Matise I, Silverstein KA, Sarver A, Starr TK, Akagi K, Tessarollo L, Collier LS, Powers S, Lowe SW, Jenkins NA, et al. A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma. Nature Biotechnology. 27: 264-74. PMID 19234449 DOI: 10.1038/Nbt.1526  0.68
2009 Yoo BK, Emdad L, Su ZZ, Villanueva A, Chiang DY, Mukhopadhyay ND, Mills AS, Waxman S, Fisher RA, Llovet JM, Fisher PB, Sarkar D. Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression. The Journal of Clinical Investigation. 119: 465-77. PMID 19221438 DOI: 10.1172/Jci36460  0.656
2009 Chiang DY, Getz G, Jaffe DB, O'Kelly MJ, Zhao X, Carter SL, Russ C, Nusbaum C, Meyerson M, Lander ES. High-resolution mapping of copy-number alterations with massively parallel sequencing. Nature Methods. 6: 99-103. PMID 19043412 DOI: 10.1038/Nmeth.1276  0.669
2009 Winslow MM, Dayton TL, Snyder EL, Chiang DY, Kim C, Verhaak R, Crowley D, Bronson RT, Meyerson M, Jacks TE. Abstract B39: Nkx2-1 down-regulation underlies lung adenocarcinoma progression towards malignancy Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-B39  0.602
2009 Villanueva A, Cornella H, Tovar V, Alsinet C, Chiang D, Peix J, Minguez B, Sara T, Savic R, Hoshida Y, Lachenmayer A, Thung S, Roayaie S, Schwartz M, Jordi B, et al. 110 MOLECULAR AND CLINICAL CHARACTERIZATION OF RICTOR (MTORC2) AS A CANDIDATE ONCOGENE IN HEPATOCELLULAR CARCINOMA Journal of Hepatology. 50: S45. DOI: 10.1016/S0168-8278(09)60112-4  0.628
2008 Villanueva A, Chiang DY, Newell P, Peix J, Thung S, Alsinet C, Tovar V, Roayaie S, Minguez B, Sole M, Battiston C, Van Laarhoven S, Fiel MI, Di Feo A, Hoshida Y, et al. Pivotal role of mTOR signaling in hepatocellular carcinoma. Gastroenterology. 135: 1972-83, 1983.e1-11. PMID 18929564 DOI: 10.1053/J.Gastro.2008.08.008  0.631
2008 Hoshida Y, Villanueva A, Kobayashi M, Peix J, Chiang DY, Camargo A, Gupta S, Moore J, Wrobel MJ, Lerner J, Reich M, Chan JA, Glickman JN, Ikeda K, Hashimoto M, et al. Gene expression in fixed tissues and outcome in hepatocellular carcinoma. The New England Journal of Medicine. 359: 1995-2004. PMID 18923165 DOI: 10.1056/Nejmoa0804525  0.636
2008 Chiang DY, Villanueva A, Hoshida Y, Peix J, Newell P, Minguez B, LeBlanc AC, Donovan DJ, Thung SN, Solé M, Tovar V, Alsinet C, Ramos AH, Barretina J, Roayaie S, et al. Focal gains of VEGFA and molecular classification of hepatocellular carcinoma. Cancer Research. 68: 6779-88. PMID 18701503 DOI: 10.1158/0008-5472.Can-08-0742  0.792
2008 Koivunen JP, Mermel C, Zejnullahu K, Murphy C, Lifshits E, Holmes AJ, Choi HG, Kim J, Chiang D, Thomas R, Lee J, Richards WG, Sugarbaker DJ, Ducko C, Lindeman N, et al. EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 4275-83. PMID 18594010 DOI: 10.1158/1078-0432.Ccr-08-0168  0.622
2008 Kulke MH, Freed E, Chiang DY, Philips J, Zahrieh D, Glickman JN, Shivdasani RA. High-resolution analysis of genetic alterations in small bowel carcinoid tumors reveals areas of recurrent amplification and loss. Genes, Chromosomes & Cancer. 47: 591-603. PMID 18383209 DOI: 10.1002/Gcc.20561  0.622
2008 Chiang D, Villanueva A, Hoshida Y, Peix J, Newell P, Minguez B, Thung S, Sole M, Tovar V, Alsinet C, Roayaie S, Schwartz M, Bruix J, Battiston C, Mazzaferro V, et al. 24 A NOVEL MOLECULAR CLASSIFICATION OF HCV-RELATED HEPATOCELLULAR CARCINOMA (HCC) BASED ON INTEGRATIVE GENOMIC ANALYSIS Journal of Hepatology. 48: S12. DOI: 10.1016/S0168-8278(08)60026-4  0.628
2008 Tovar V, Alsinet C, Cabellos L, Sole M, Villanueva A, Chiang D, Moyano S, Schwartz M, Mazzaferro V, Bruix J, Llovet J. 2 DISRUPTION OF IGF SIGNALING IN EARLY HEPATOCELLULAR CARCINOMA AND PRE-CLINICAL EFFICACY OF ANTI-IGF1R BLOCKING THERAPIES Journal of Hepatology. 48: S3. DOI: 10.1016/S0168-8278(08)60004-5  0.612
2007 Shultzaberger RK, Chiang DY, Moses AM, Eisen MB. Determining physical constraints in transcriptional initiation complexes using DNA sequence analysis. Plos One. 2: e1199. PMID 18030333 DOI: 10.1371/Journal.Pone.0001199  0.777
2007 Weir BA, Woo MS, Getz G, Perner S, Ding L, Beroukhim R, Lin WM, Province MA, Kraja A, Johnson LA, Shah K, Sato M, Thomas RK, Barletta JA, Borecki IB, ... Chiang DY, et al. Characterizing the cancer genome in lung adenocarcinoma. Nature. 450: 893-8. PMID 17982442 DOI: 10.1038/Nature06358  0.758
2007 Villanueva A, Newell P, Chiang DY, Friedman SL, Llovet JM. Genomics and signaling pathways in hepatocellular carcinoma. Seminars in Liver Disease. 27: 55-76. PMID 17295177 DOI: 10.1055/S-2006-960171  0.662
2006 Chiang DY, Nix DA, Shultzaberger RK, Gasch AP, Eisen MB. Flexible promoter architecture requirements for coactivator recruitment. Bmc Molecular Biology. 7: 16. PMID 16646957 DOI: 10.1186/1471-2199-7-16  0.782
2004 Moses AM, Chiang DY, Pollard DA, Iyer VN, Eisen MB. MONKEY: identifying conserved transcription-factor binding sites in multiple alignments using a binding site-specific evolutionary model. Genome Biology. 5: R98. PMID 15575972 DOI: 10.1186/Gb-2004-5-12-R98  0.771
2004 Gasch AP, Moses AM, Chiang DY, Fraser HB, Berardini M, Eisen MB. Conservation and evolution of cis-regulatory systems in ascomycete fungi. Plos Biology. 2: e398. PMID 15534694 DOI: 10.1371/Journal.Pbio.0020398  0.784
2004 Moses AM, Chiang DY, Eisen MB. Phylogenetic motif detection by expectation-maximization on evolutionary mixtures. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 324-35. PMID 14992514  0.761
2003 Moses AM, Chiang DY, Kellis M, Lander ES, Eisen MB. Position specific variation in the rate of evolution in transcription factor binding sites. Bmc Evolutionary Biology. 3: 19. PMID 12946282 DOI: 10.1186/1471-2148-3-19  0.77
2003 Chiang DY, Moses AM, Kellis M, Lander ES, Eisen MB. Phylogenetically and spatially conserved word pairs associated with gene-expression changes in yeasts. Genome Biology. 4: R43. PMID 12844359 DOI: 10.1186/Gb-2003-4-7-R43  0.788
2003 Chiang DY, Moses AM, Kamvysselis M, Lander ES, Eisen MB. Phylogenetically and spatially conserved word pairs associated with gene expression changes in yeasts Proceedings of the Annual International Conference On Computational Molecular Biology, Recomb. 84-93.  0.74
2001 Chiang DY, Brown PO, Eisen MB. Visualizing associations between genome sequences and gene expression data using genome-mean expression profiles. Bioinformatics (Oxford, England). 17: S49-55. PMID 11472992 DOI: 10.1093/Bioinformatics/17.Suppl_1.S49  0.77
2000 Abe K, Rossman KL, Liu B, Ritola KD, Chiang D, Campbell SL, Burridge K, Der CJ. Vav2 is an activator of Cdc42, Rac1, and RhoA. The Journal of Biological Chemistry. 275: 10141-9. PMID 10744696 DOI: 10.1074/Jbc.275.14.10141  0.607
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