| Year |
Citation |
Score |
| 2024 |
Patel AG, Ashenberg O, Collins NB, Segerstolpe Å, Jiang S, Slyper M, Huang X, Caraccio C, Jin H, Sheppard H, Xu K, Chang TC, Orr BA, Shirinifard A, Chapple RH, et al. A spatial cell atlas of neuroblastoma reveals developmental, epigenetic and spatial axis of tumor heterogeneity. Biorxiv : the Preprint Server For Biology. PMID 38260392 DOI: 10.1101/2024.01.07.574538 |
0.315 |
|
| 2023 |
Okonechnikov K, Joshi P, Sepp M, Leiss K, Sarropoulos I, Murat F, Sill M, Beck P, Chan KC, Korshunov A, Sahm F, Deng MY, Sturm D, DeSisto J, Donson AM, ... ... Orr BA, et al. Mapping pediatric brain tumors to their origins in the developing cerebellum. Neuro-Oncology. PMID 37534924 DOI: 10.1093/neuonc/noad124 |
0.389 |
|
| 2023 |
Madsen PJ, Hollawell ML, Santi M, Surrey LF, Vossough A, Orr BA, Hill-Kayser C, Tucker AM, Storm PB, Foster JB. Diffuse leptomeningeal glioneuronal tumor in a child masquerading as an intramedullary spinal pilocytic astrocytoma. Neuro-Oncology Advances. 5: vdad049. PMID 37197736 DOI: 10.1093/noajnl/vdad049 |
0.304 |
|
| 2022 |
Howden K, McDonald PJ, Kazina C, Ong A, Ho B, Huang A, Orr BA, Vanan MI. Sustained and durable response with Alisertib monotherapy in the treatment of relapsed Atypical Teratoid Rhabdoid Tumor (ATRT). Neuro-Oncology Advances. 4: vdac090. PMID 35967099 DOI: 10.1093/noajnl/vdac090 |
0.324 |
|
| 2022 |
Upadhyaya SA, Campagne O, Billups CA, Orr BA, Onar-Thomas A, Tatevossian RG, Mostafavi R, Myers JR, Vinitsky A, Moreira DC, Lindsay HB, Kilburn L, Baxter P, Smith A, Crawford JR, et al. Phase II study of alisertib as a single agent for treating recurrent or progressive atypical teratoid/rhabdoid tumor. Neuro-Oncology. PMID 35652336 DOI: 10.1093/neuonc/noac151 |
0.347 |
|
| 2022 |
Arunachalam S, Szlachta K, Brady SW, Ma X, Ju B, Shaner B, Mulder HL, Easton J, Raphael BJ, Myers M, Tinkle C, Allen SJ, Orr BA, Wetmore CJ, Baker SJ, et al. Convergent evolution and multi-wave clonal invasion in H3 K27-altered diffuse midline gliomas treated with a PDGFR inhibitor. Acta Neuropathologica Communications. 10: 80. PMID 35642016 DOI: 10.1186/s40478-022-01381-0 |
0.316 |
|
| 2021 |
Newman S, Nakitandwe J, Kesserwan CA, Azzato EM, Wheeler DA, Rusch M, Shurtleff S, Hedges DJ, Hamilton KV, Foy SG, Edmonson MN, Thrasher A, Bahrami A, Orr BA, Klco JM, et al. Genomes for Kids: The scope of pathogenic mutations in pediatric cancer revealed by comprehensive DNA and RNA sequencing. Cancer Discovery. PMID 34301788 DOI: 10.1158/2159-8290.CD-20-1631 |
0.313 |
|
| 2021 |
Doucet-O'Hare TT, DiSanza BL, DeMarino C, Atkinson AL, Rosenblum JS, Henderson LJ, Johnson KR, Kowalak J, Garcia-Montojo M, Allen SJ, Orr BA, Santi M, Wang T, Fathi S, Lee MH, et al. SMARCB1 deletion in atypical teratoid rhabdoid tumors results in human endogenous retrovirus K (HML-2) expression. Scientific Reports. 11: 12893. PMID 34145313 DOI: 10.1038/s41598-021-92223-x |
0.302 |
|
| 2021 |
Schieffer KM, Feldman AZ, Kautto EA, McGrath S, Miller AR, Hernandez-Gonzalez ME, LaHaye S, Miller KE, Koboldt DC, Brennan P, Kelly B, Wetzel A, Agarwal V, Shatara M, Conley S, ... ... Orr BA, et al. Molecular classification of a complex structural rearrangement of the RB1 locus in an infant with sporadic, isolated, intracranial, sellar region retinoblastoma. Acta Neuropathologica Communications. 9: 61. PMID 33827698 DOI: 10.1186/s40478-021-01164-z |
0.301 |
|
| 2020 |
Kutscher LM, Okonechnikov K, Batora NV, Clark J, Silva PBG, Vouri M, van Rijn S, Sieber L, Statz B, Gearhart MD, Shiraishi R, Mack N, Orr BA, Korshunov A, Gudenas BL, et al. Functional loss of a noncanonical BCOR-PRC1.1 complex accelerates SHH-driven medulloblastoma formation. Genes & Development. PMID 32820036 DOI: 10.1101/Gad.337584.120 |
0.467 |
|
| 2020 |
Liu APY, Priesterbach-Ackley LP, Orr BA, Li BK, Gudenas B, Reddingius RE, Suñol M, Lavarino CE, Olaciregui NG, Santa-María López V, Fisher MJ, Hazrati LN, Bouffet E, Huang A, Robinson GW, et al. WNT-activated embryonal tumors of the pineal region: ectopic medulloblastomas or a novel pineoblastoma subgroup? Acta Neuropathologica. PMID 32772175 DOI: 10.1007/S00401-020-02208-9 |
0.437 |
|
| 2020 |
Vaubel R, Zschernack V, Tran QT, Jenkins S, Caron A, Milosevic D, Smadbeck J, Vasmatzis G, Kandels D, Gnekow A, Kramm C, Jenkins R, Kipp BR, Rodriguez FJ, Orr BA, et al. Biology and grading of pleomorphic xanthoastrocytoma-what have we learned about it? Brain Pathology (Zurich, Switzerland). PMID 32619305 DOI: 10.1111/Bpa.12874 |
0.363 |
|
| 2020 |
Smith KS, Xu K, Mercer KS, Boop F, Klimo P, DeCupyere M, Grenet J, Robinson S, Dunphy P, Baker SJ, Ellison DW, Merchant TE, Upadayaya SA, Gajjar A, Wu G, ... Orr BA, et al. Patient-derived orthotopic xenografts of pediatric brain tumors: a St. Jude resource. Acta Neuropathologica. PMID 32519082 DOI: 10.1007/S00401-020-02171-5 |
0.483 |
|
| 2020 |
Louis DN, Wesseling P, Aldape K, Brat DJ, Capper D, Cree IA, Eberhart C, Figarella-Branger D, Fouladi M, Fuller GN, Giannini C, Haberler C, Hawkins C, Komori T, Kros JM, ... ... Orr BA, et al. cIMPACT-NOW update 6: new entity and diagnostic principle recommendations of the cIMPACT-Utrecht meeting on future CNS tumor classification and grading. Brain Pathology (Zurich, Switzerland). PMID 32307792 DOI: 10.1111/Bpa.12832 |
0.431 |
|
| 2020 |
Mondal G, Lee JC, Ravindranathan A, Villanueva-Meyer JE, Tran QT, Allen SJ, Barreto J, Gupta R, Doo P, Van Ziffle J, Onodera C, Devine P, Grenert JP, Samuel D, Li R, ... ... Orr BA, et al. Pediatric bithalamic gliomas have a distinct epigenetic signature and frequent EGFR exon 20 insertions resulting in potential sensitivity to targeted kinase inhibition. Acta Neuropathologica. PMID 32303840 DOI: 10.1007/S00401-020-02155-5 |
0.36 |
|
| 2020 |
Waszak SM, Robinson GW, Gudenas BL, Smith KS, Forget A, Kojic M, Garcia-Lopez J, Hadley J, Hamilton KV, Indersie E, Buchhalter I, Kerssemakers J, Jäger N, Sharma T, Rausch T, ... ... Orr BA, et al. Germline Elongator mutations in Sonic Hedgehog medulloblastoma. Nature. 580: 396-401. PMID 32296180 DOI: 10.1038/S41586-020-2164-5 |
0.304 |
|
| 2020 |
Orr BA. Pathology, Diagnostics, and Classification of Medulloblastoma. Brain Pathology (Zurich, Switzerland). PMID 32239782 DOI: 10.1111/Bpa.12837 |
0.394 |
|
| 2020 |
Pujadas E, Chen L, Weingart JD, Orr B, Ozer BH, Holdhoff M, Rodriguez FJ. alterations in anaplastic ependymoma progression to ependymosarcoma. Clinical Neuropathology. PMID 32017698 DOI: 10.5414/Np301240 |
0.398 |
|
| 2020 |
Wijaya J, Vo BT, Liu J, Xu B, Wu G, Wang Y, Peng J, Zhang J, Janke LJ, Orr BA, Yu J, Roussel MF, Schuetz JD. An ABC transporter drives medulloblastoma pathogenesis by regulating Sonic Hedgehog signaling. Cancer Research. PMID 31948942 DOI: 10.1158/0008-5472.Can-19-2054 |
0.486 |
|
| 2020 |
Whiteway SL, Betts AM, O'Neil ER, Green AL, Gilani A, Orr BA, Mathis DA. Oncogenic GOPC-ROS1 Fusion Identified in a Congenital Glioblastoma Case. Journal of Pediatric Hematology/Oncology. PMID 31929384 DOI: 10.1097/Mph.0000000000001711 |
0.387 |
|
| 2020 |
Upadhyaya S, Campagne O, Robinson GW, Onar-Thomas A, Orr B, Billups CA, Tatevossian RG, Broniscer A, Kilburn LB, Baxter PA, Smith AA, Crawford J, Partap S, Ellison DW, Stewart CF, et al. Phase II study of alisertib as a single agent in recurrent or progressive atypical teratoid rhabdoid tumors. Journal of Clinical Oncology. 38: 10542-10542. DOI: 10.1200/Jco.2020.38.15_Suppl.10542 |
0.309 |
|
| 2020 |
Dunphy PS, Xu K, Gentry DT, He C, Mercer K, Zhu X, Smith K, Gudenas B, Robinson S, Zhang J, Kasper LH, Kwon C, Hover LD, Larson JD, Twarog N, ... ... Orr BA, et al. Abstract 6144: St. Jude Pediatric Brain Tumor Portal: Cloud-based resource for patient-derived orthotopic xenograft (PDOX) models of pediatric high-grade glioma, ependymoma, and CNS embryonal tumors Tumor Biology. DOI: 10.1158/1538-7445.Am2020-6144 |
0.473 |
|
| 2019 |
Clay MR, Pinto EM, Cline C, Tran QT, Lin T, Dyer MA, Shi L, Wu H, Pounds SB, Zambetti GP, Orr BA, Ribeiro RC. DNA Methylation Profiling Reveals Prognostically Significant Groups in Pediatric Adrenocortical Tumors: A Report From the International Pediatric Adrenocortical Tumor Registry. Jco Precision Oncology. 3. PMID 32923859 DOI: 10.1200/PO.19.00163 |
0.307 |
|
| 2019 |
Bernstock JD, Alva E, Cohen JL, Lobbous M, Chagoya G, Elsayed GA, Orr BA, Rozzelle C, Rocque B, Blount J, Johnston JM, Li R, Fiveash JB, Dhall G, Reddy AT, et al. Treatment of pediatric high-grade central nervous system tumors with high-dose methotrexate in combination with multiagent chemotherapy: A single-institution experience. Pediatric Blood & Cancer. e28119. PMID 31850678 DOI: 10.1002/Pbc.28119 |
0.382 |
|
| 2019 |
Liu APY, Gudenas B, Lin T, Orr BA, Klimo P, Kumar R, Bouffet E, Gururangan S, Crawford JR, Kellie SJ, Chintagumpala M, Fisher MJ, Bowers DC, Hassall T, Indelicato DJ, et al. Risk-adapted therapy and biological heterogeneity in pineoblastoma: integrated clinico-pathological analysis from the prospective, multi-center SJMB03 and SJYC07 trials. Acta Neuropathologica. PMID 31802236 DOI: 10.1007/S00401-019-02106-9 |
0.357 |
|
| 2019 |
Pfaff E, Aichmüller C, Sill M, Stichel D, Snuderl M, Karajannis MA, Schuhmann MU, Schittenhelm J, Hasselblatt M, Thomas C, Korshunov A, Rhizova M, Wittmann A, Kaufhold A, Iskar M, ... ... Orr BA, et al. Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations. Acta Neuropathologica. PMID 31768671 DOI: 10.1007/S00401-019-02101-0 |
0.465 |
|
| 2019 |
Orr BA, Clay MR, Pinto EM, Kesserwan C. An update on the central nervous system manifestations of Li-Fraumeni syndrome. Acta Neuropathologica. PMID 31468188 DOI: 10.1007/S00401-019-02055-3 |
0.391 |
|
| 2019 |
Wang SZ, Poore B, Alt J, Price A, Allen SJ, Hanaford AR, Kaur H, Orr BA, Slusher BS, Eberhart CG, Raabe EH, Rubens JA. Unbiased metabolic profiling predicts sensitivity of high MYC-expressing atypical teratoid/rhabdoid tumors to glutamine inhibition with 6-diazo-5-oxo-L-norleucine. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31300448 DOI: 10.1158/1078-0432.Ccr-19-0189 |
0.47 |
|
| 2019 |
Lehman NL, Usubalieva A, Lin T, Allen SJ, Tran QT, Mobley BC, McLendon RE, Schniederjan MJ, Georgescu MM, Couce M, Dulai MS, Raisanen JM, Al Abbadi M, Palmer CA, Hattab EM, ... Orr BA, et al. Genomic analysis demonstrates that histologically-defined astroblastomas are molecularly heterogeneous and that tumors with MN1 rearrangement exhibit the most favorable prognosis. Acta Neuropathologica Communications. 7: 42. PMID 30876455 DOI: 10.1186/S40478-019-0689-3 |
0.483 |
|
| 2019 |
El Ahmadieh TY, Plitt A, Kafka B, Aoun SG, Raisanen JM, Orr B, Pan E, Wardak Z, Nedzi LA, Patel TR. H3 K27M Mutations in Thalamic Pilocytic Astrocytomas with Anaplasia. World Neurosurgery. PMID 30639498 DOI: 10.1016/J.Wneu.2018.12.147 |
0.391 |
|
| 2019 |
Clay M, Pinto E, Cline C, Tran Q, Lin T, Wu H, Azzato E, Pappo A, Dyer M, Pounds S, Ellison D, Zambetti G, Orr B, Ribeiro R. OR02-1 DNA Methylation Profiling in Pediatric Adrenocortical Tumors Reveals Distinct Methylation Signatures with Prognostic Significance: A Report from the International Pediatric Adrenocortical Tumor Registry Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Or02-1 |
0.415 |
|
| 2019 |
Wang SZ, Poore B, Alt J, Price A, Allen S, Orr B, Rais R, Slusher B, Eberhart C, Raabe EH, Rubens JH. Abstract 5267: Unbiased metabolic profiling of atypical teratoid/rhabdoid tumors predicts sensitivity to the glutamine metabolic inhibitor 6-diazo-5-oxo-L-norleucine Cancer Research. 79: 5267-5267. DOI: 10.1158/1538-7445.Sabcs18-5267 |
0.402 |
|
| 2019 |
Bihannic L, Hovestadt V, Smith K, Filbin M, Shaw M, Baumgartner A, DeWitt J, Groves A, Mayr L, Weisman H, Richman A, Shore M, Goumnerova L, Rosencrance C, Carter R, ... ... Orr B, et al. PDTM-32. RESOLVING MEDULLOBLASTOMA CELLULAR ARCHITECTURE BY SINGLE-CELL GENOMICS Neuro-Oncology. 21: vi194-vi194. DOI: 10.1093/Neuonc/Noz175.808 |
0.444 |
|
| 2019 |
Kutscher L, Batora N, Okonechnikov K, Clark J, Vouri M, Rijn Sv, Gearhart M, Orr B, Korshunov A, Kool M, Bardwell V, Pfister SM, Northcott PA, Kawauchi D. MEDU-21. LOSS OF THE TRANSCRIPTIONAL CO-REPRESSOR BCOR LEADS TO OVEREXPRESSION OF THE GROWTH FACTOR IGF2 AND SHH MEDULLOBLASTOMA TUMOR FORMATION Neuro-Oncology. 21: ii107-ii108. DOI: 10.1093/Neuonc/Noz036.180 |
0.363 |
|
| 2019 |
Pfaff E, Aichmüller C, Sill M, Stichel D, Snuderl M, Karajannis MA, Schuhmann MU, Schittenhelm J, Hasselblatt M, Thomas C, Korshunov A, Rhizova M, Temming P, Orr BA, Ellison DW, et al. GENE-06. DISTINCT MOLECULAR SUBGROUPS OF TUMORS OF THE PINEAL REGION CORRELATE WITH CLINICAL PARAMETERS AND GENETIC ALTERATIONS Neuro-Oncology. 21: ii81-ii82. DOI: 10.1093/Neuonc/Noz036.077 |
0.384 |
|
| 2019 |
Wang S, Poore B, Alt J, Price A, Allen S, Orr B, Rais R, Slusher B, Eberhart C, Raabe E, Rubens J. ATRT-04. UNBIASED METABOLIC PROFILING OF ATYPICAL TERATOID/RHABDOID TUMORS PREDICTS SENSITIVITY TO GLUTAMINE METABOLIC INHIBITORS Neuro-Oncology. 21: ii63-ii63. DOI: 10.1093/Neuonc/Noz036.003 |
0.34 |
|
| 2018 |
Lin B, Kesserwan C, Quinn EA, Einhaus SL, Wright KD, Azzato EM, Orr BA, Upadhyaya SA. Anaplastic Astrocytoma in a Child With Coffin-Siris Syndrome and a Germline SMARCE1 Mutation: A Case Report. Journal of Pediatric Hematology/Oncology. PMID 30499906 DOI: 10.1097/Mph.0000000000001361 |
0.346 |
|
| 2018 |
Smith SMC, Bianski BM, Orr BA, Harknett G, Onar-Thomas A, Gilbertson RJ, Merchant TE, Roussel MF, Tinkle CL. Preclinical Modeling of Image-Guided Craniospinal Irradiation for Very-High-Risk Medulloblastoma. International Journal of Radiation Oncology, Biology, Physics. PMID 30366006 DOI: 10.1016/J.Ijrobp.2018.10.015 |
0.365 |
|
| 2018 |
Kumar R, Liu APY, Orr BA, Northcott PA, Robinson GW. Advances in the classification of pediatric brain tumors through dna methylation profiling: from research tool to frontline diagnostic. Cancer. PMID 30255939 DOI: 10.1002/Cncr.31583 |
0.459 |
|
| 2018 |
Rodriguez FJ, Brosnan-Cashman JA, Allen SJ, Vizcaino MA, Giannini C, Camelo-Piragua S, Webb M, Matsushita M, Wadhwani N, Tabbarah A, Hamideh D, Jiang L, Chen L, Arvanitis LD, Alnajar HH, ... ... Orr B, et al. Alternative lengthening of telomeres, ATRX loss and h3-k27m mutations in histologically defined pilocytic astrocytoma with anaplasia. Brain Pathology (Zurich, Switzerland). PMID 30192422 DOI: 10.1111/Bpa.12646 |
0.351 |
|
| 2018 |
Murdock T, Orr B, Allen S, Ibrahim J, Sharma R, Ronnett BM, Rodriguez FJ. Central Nervous System-type Neuroepithelial Tumors and Tumor-like Proliferations Developing in the Gynecologic Tract and Pelvis: Clinicopathologic Analysis of 23 Cases. The American Journal of Surgical Pathology. PMID 30074494 DOI: 10.1097/Pas.0000000000001131 |
0.501 |
|
| 2018 |
Vo BT, Kwon JA, Li C, Finkelstein D, Xu B, Orr BA, Sherr CJ, Roussel MF. Mouse medulloblastoma driven by CRISPR activation of cellular Myc. Scientific Reports. 8: 8733. PMID 29880921 DOI: 10.1038/S41598-018-24956-1 |
0.37 |
|
| 2018 |
Santiago T, Clay MR, Allen SJ, Orr BA. Recurrent BCOR internal tandem duplication and BCOR or BCL6 expression distinguish primitive myxoid mesenchymal tumor of infancy from congenital infantile fibrosarcoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 31: 374. PMID 29430000 DOI: 10.1038/modpathol.2017.178 |
0.302 |
|
| 2018 |
Pinto EM, Hamideh D, Bahrami A, Orr BA, Lin T, Pounds S, Zambetti GP, Pappo AS, Gajjar A, Agnihotri S, Broniscer A. Malignant rhabdoid tumors originating within and outside the central nervous system are clinically and molecularly heterogeneous. Acta Neuropathologica. PMID 29428974 DOI: 10.1007/S00401-018-1814-2 |
0.484 |
|
| 2018 |
Upadhyaya SA, Robinson GW, Harreld JH, Klimo PD, Hoehn ME, Orr BA, Qaddoumi IA. Marked functional recovery and imaging response of refractory optic pathway glioma to BRAFV600E inhibitor therapy: a report of two cases. Child's Nervous System : Chns : Official Journal of the International Society For Pediatric Neurosurgery. PMID 29392423 DOI: 10.1007/S00381-018-3739-4 |
0.325 |
|
| 2018 |
Wang SZ, Poore B, Alt J, Rais R, Allen S, Orr B, Slusher B, Eberhart C, Raabe E, Rubens J. Abstract 3519: Disrupting glutamine metabolism depletes glutathione and sensitizes atypical teratoid/rhabdoid tumor to carboplatin Cancer Research. 78: 3519-3519. DOI: 10.1158/1538-7445.Am2018-3519 |
0.452 |
|
| 2018 |
Lucas J, Hsu C, Lu Z, Becksfort J, Tinkle C, Broniscer A, Merchant T, Orr B, Baker S, Patay Z, Hwang S. Hgg-35. Combinations Of Quantitative And Qualitative Mri Features Identify Prognostic And Molecular Subgroups Of Supratentorial Pediatric High-Grade Glioma Neuro-Oncology. 20. DOI: 10.1093/Neuonc/Noy059.307 |
0.313 |
|
| 2018 |
Liu A, Orr B, Lin T, Hassall T, Bowers DC, Bouffet E, Gururangan S, Fisher P, Crawford J, Kellie SJ, Chintagumpala M, Fisher M, Bendel A, Ellison D, Robinson G, et al. Embr-14. Reclassification Of Central Nervous System Primitive Neuroectodermal Tumor (Cns-Pnet) Into Entities Reflects Outcome: Results From The Prospective Sjyc07 And Sjmb03 Trials Neuro-Oncology. 20. DOI: 10.1093/Neuonc/Noy059.198 |
0.402 |
|
| 2018 |
Pfaff E, Snuderl M, Karajannis MA, Aichmüller C, Sill M, Orr BA, Ellison DW, Pfister SM, Jones DTW. Embr-05. Tumors Of The Pineal Region Can Be Classified Into Distinct Subgroups Based On Molecular Characteristics Correlating With Clinical Parameters And Genetic Alterations Neuro-Oncology. 20. DOI: 10.1093/Neuonc/Noy059.190 |
0.389 |
|
| 2018 |
Pinto E, Hamideh D, Bahrami A, Orr B, Lin T, Pounds S, Zambetti G, Pappo A, Agnihotri S, Gajjar A, Broniscer A. Atrt-03. Malignant Rhabdoid Tumors Originating Within And Outside The Central Nervous System Are Clinically And Molecularly Heterogeneous Neuro-Oncology. 20. DOI: 10.1093/Neuonc/Noy059.002 |
0.459 |
|
| 2017 |
Lee RP, Foster KA, Lillard JC, Klimo P, Ellison DW, Orr B, Boop FA. Surgical and molecular considerations in the treatment of pediatric thalamopeduncular tumors. Journal of Neurosurgery. Pediatrics. 1-9. PMID 28686121 DOI: 10.3171/2017.4.Peds16668 |
0.425 |
|
| 2017 |
Rubens JA, Wang SZ, Price A, Weingart MF, Allen SJ, Orr BA, Eberhart CG, Raabe EH. The TORC1/2 inhibitor TAK228 sensitizes atypical teratoid rhabdoid tumors to cisplatin-induced cytotoxicity. Neuro-Oncology. PMID 28582547 DOI: 10.1093/Neuonc/Nox067 |
0.45 |
|
| 2017 |
Chiang JCH, Harreld JH, Orr BA, Sharma S, Ismail A, Segura AD, Ellison DW. Low-grade spinal glioneuronal tumors with BRAF gene fusion and 1p deletion but without leptomeningeal dissemination. Acta Neuropathologica. PMID 28547128 DOI: 10.1007/S00401-017-1728-4 |
0.377 |
|
| 2017 |
Vo BT, Li C, Morgan MA, Theurillat I, Finkelstein D, Wright S, Hyle J, Smith SM, Fan Y, Wang YD, Wu G, Orr BA, Northcott PA, Shilatifard A, Sherr CJ, et al. Inactivation of Ezh2 Upregulates Gfi1 and Drives Aggressive Myc-Driven Group 3 Medulloblastoma. Cell Reports. 18: 2907-2917. PMID 28329683 DOI: 10.1016/J.Celrep.2017.02.073 |
0.445 |
|
| 2017 |
Parikh KA, Venable GT, Orr BA, Choudhri AF, Boop FA, Gajjar AJ, Klimo P. Pineoblastoma-The Experience at St. Jude Children's Research Hospital. Neurosurgery. PMID 28327927 DOI: 10.1093/Neuros/Nyx005 |
0.349 |
|
| 2017 |
Santiago T, Clay MR, Allen SJ, Orr BA. Recurrent BCOR internal tandem duplication and BCOR or BCL6 expression distinguish primitive myxoid mesenchymal tumor of infancy from congenital infantile fibrosarcoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 28256570 DOI: 10.1038/Modpathol.2017.12 |
0.502 |
|
| 2017 |
Wang S, Rubens J, Allen S, Orr B, Eberhart C, Raabe E. Abstract 5182: Targeting abnormal metabolism downstream of MYC in atypical teratoid/rhabdoid tumors Cancer Research. 77: 5182-5182. DOI: 10.1158/1538-7445.Am2017-5182 |
0.436 |
|
| 2017 |
Rubens J, Wang S, Price A, Allen S, Orr B, Eberhart C, Raabe E. ATRT-08. TARGETING GLUTAMINE METABOLISM IN MYC DRIVEN ATYPICAL TERATOID RHABDOID TUMORS Neuro-Oncology. 19: iv2-iv3. DOI: 10.1093/Neuonc/Nox083.007 |
0.413 |
|
| 2016 |
Broniscer A, Hwang SN, Chamdine O, Lin T, Pounds S, Onar-Thomas A, Chi L, Shurtleff S, Allen S, Gajjar A, Northcott P, Orr BA. Bithalamic Gliomas May Be Molecularly Distinct From Their Unilateral High-Grade Counterparts. Brain Pathology (Zurich, Switzerland). PMID 28032389 DOI: 10.1111/Bpa.12484 |
0.429 |
|
| 2016 |
Georgescu MM, Mobley BC, Orr BA, Shang P, Lehman NL, Zhu X, O'Neill TJ, Rajaram V, Hatanpaa KJ, Timmons CF, Raisanen JM. NHERF1/EBP50 and NF2 as diagnostic markers for choroid plexus tumors. Acta Neuropathologica Communications. 4: 55. PMID 27229317 DOI: 10.1186/S40478-016-0329-0 |
0.431 |
|
| 2016 |
Binder ZA, Wilson KM, Salmasi V, Orr BA, Eberhart CG, Siu IM, Lim M, Weingart JD, Quinones-Hinojosa A, Bettegowda C, Kassam AB, Olivi A, Brem H, Riggins GJ, Gallia GL. Establishment and Biological Characterization of a Panel of Glioblastoma Multiforme (GBM) and GBM Variant Oncosphere Cell Lines. Plos One. 11: e0150271. PMID 27028405 DOI: 10.1371/Journal.Pone.0150271 |
0.398 |
|
| 2016 |
Sturm D, Orr BA, Toprak UH, Hovestadt V, Jones DT, Capper D, Sill M, Buchhalter I, Northcott PA, Leis I, Ryzhova M, Koelsche C, Pfaff E, Allen SJ, Balasubramanian G, et al. New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs. Cell. 164: 1060-1072. PMID 26919435 DOI: 10.1016/J.Cell.2016.01.015 |
0.497 |
|
| 2016 |
Lin CY, Erkek S, Tong Y, Yin L, Federation AJ, Zapatka M, Haldipur P, Kawauchi D, Risch T, Warnatz HJ, Worst BC, Ju B, Orr BA, Zeid R, Polaski DR, et al. Active medulloblastoma enhancers reveal subgroup-specific cellular origins. Nature. PMID 26814967 DOI: 10.1038/Nature16546 |
0.312 |
|
| 2016 |
Broniscer A, Chamdine O, Hwang S, Lin T, Pounds S, Onar-Thomas A, Shurtleff S, Allen S, Gajjar A, Northcott P, Orr BA. Gliomatosis cerebri in children shares molecular characteristics with other pediatric gliomas. Acta Neuropathologica. PMID 26744350 DOI: 10.1007/S00401-015-1532-Y |
0.409 |
|
| 2016 |
Sturm D, Orr B, Toprak UH, Hovestadt V, Jones DTW, Capper D, Lichter P, Korshunov A, Pfister SM, Ellison DW, Kool M. Abstract 2696: Four new brain tumor entities emerge from molecular classification of CNS-PNETs Cancer Research. 76: 2696-2696. DOI: 10.1158/1538-7445.Am2016-2696 |
0.419 |
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| 2016 |
Rubens J, Price A, Orr B, Eberhart C, Raabe E. Abstract 2102: Targeting mTOR downstream of LIN28 in atypical teratoid rhabdoid tumors promotes apoptosis and suppresses tumorigenicity Cancer Research. 76: 2102-2102. DOI: 10.1158/1538-7445.Am2016-2102 |
0.41 |
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| 2016 |
Sturm D, Orr B, Toprak U, Hovestadt V, Jones D, Capper D, Rijn Sv, Kawauchi D, Lichter P, Korshunov A, Pfister S, Ellison D, Kool M. PNR-21FOUR NEW BRAIN TUMOR ENTITIES EMERGE FROM MOLECULAR CLASSIFICATION OF CNS PNETs Neuro-Oncology. 18. DOI: 10.1093/Neuonc/Now067.18 |
0.421 |
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| 2016 |
Vanan MI, McDonald P, Kazina C, Liu J, Krawitz S, Bunge M, Ong A, Orr B. At-22Alisertib Monotherapy In The Treatment Of Relapsed Atypical Teratoid Rhabdoid Tumor (Atrt) Neuro-Oncology. 18. DOI: 10.1093/Neuonc/Now065.21 |
0.439 |
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| 2015 |
Klimo P, Nesvick CL, Broniscer A, Orr BA, Choudhri AF. Malignant brainstem tumors in children, excluding diffuse intrinsic pontine gliomas. Journal of Neurosurgery. Pediatrics. 1-9. PMID 26474099 DOI: 10.3171/2015.6.Peds15166 |
0.408 |
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| 2015 |
Ho CY, Mobley BC, Gordish-Dressman H, VandenBussche CJ, Mason GE, Bornhorst M, Esbenshade AJ, Tehrani M, Orr BA, LaFrance DR, Devaney JM, Meltzer BW, Hofherr SE, Burger PC, Packer RJ, et al. A clinicopathologic study of diencephalic pediatric low-grade gliomas with BRAF V600 mutation. Acta Neuropathologica. 130: 575-85. PMID 26264609 DOI: 10.1007/S00401-015-1467-3 |
0.384 |
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| 2015 |
Kahlert UD, Suwala AK, Koch K, Natsumeda M, Orr BA, Hayashi M, Maciaczyk J, Eberhart CG. Pharmacologic Wnt Inhibition Reduces Proliferation, Survival, and Clonogenicity of Glioblastoma Cells. Journal of Neuropathology and Experimental Neurology. 74: 889-900. PMID 26222502 DOI: 10.1097/Nen.0000000000000227 |
0.371 |
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| 2015 |
Robinson GW, Orr BA, Wu G, Gururangan S, Lin T, Qaddoumi I, Packer RJ, Goldman S, Prados MD, Desjardins A, Chintagumpala M, Takebe N, Kaste SC, Rusch M, Allen SJ, et al. Vismodegib Exerts Targeted Efficacy Against Recurrent Sonic Hedgehog-Subgroup Medulloblastoma: Results From Phase II Pediatric Brain Tumor Consortium Studies PBTC-025B and PBTC-032. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 26169613 DOI: 10.1200/Jco.2014.60.1591 |
0.344 |
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| 2015 |
Oh CC, Orr BA, Bernardi B, Garré ML, Rossi A, Figà-Talamanca L, Robinson GW, Patay Z. Atypical teratoid/rhabdoid tumor (ATRT) arising from the 3rd cranial nerve in infants: a clinical-radiological entity? Journal of Neuro-Oncology. PMID 26148473 DOI: 10.1007/S11060-015-1787-0 |
0.375 |
|
| 2015 |
McAbee JH, Modica J, Thompson CJ, Broniscer A, Orr B, Choudhri AF, Boop FA, Klimo P. Cervicomedullary tumors in children. Journal of Neurosurgery. Pediatrics. 1-10. PMID 26114990 DOI: 10.3171/2015.5.Peds14638 |
0.401 |
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| 2015 |
Wetmore C, Boyett J, Li S, Lin T, Bendel A, Gajjar A, Orr BA. Alisertib is active as single agent in recurrent atypical teratoid rhabdoid tumors in 4 children. Neuro-Oncology. 17: 882-8. PMID 25688119 DOI: 10.1093/Neuonc/Nov017 |
0.512 |
|
| 2015 |
Ju B, Chen W, Orr BA, Spitsbergen JM, Jia S, Eden CJ, Henson HE, Taylor MR. Oncogenic KRAS promotes malignant brain tumors in zebrafish. Molecular Cancer. 14: 18. PMID 25644510 DOI: 10.1186/S12943-015-0288-2 |
0.45 |
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| 2015 |
Weingart MF, Roth JJ, Hutt-Cabezas M, Busse TM, Kaur H, Price A, Maynard R, Rubens J, Taylor I, Mao XG, Xu J, Kuwahara Y, Allen SJ, Erdreich-Epstein A, Weissman BE, ... Orr BA, et al. Disrupting LIN28 in atypical teratoid rhabdoid tumors reveals the importance of the mitogen activated protein kinase pathway as a therapeutic target. Oncotarget. 6: 3165-77. PMID 25638158 DOI: 10.18632/Oncotarget.3078 |
0.465 |
|
| 2015 |
Tsui K, Gajjar A, Li C, Srivastava D, Broniscer A, Wetmore C, Kun LE, Merchant TE, Ellison DW, Orr BA, Boop FA, Klimo P, Ross J, Robison LL, Armstrong GT. Subsequent neoplasms in survivors of childhood central nervous system tumors: risk after modern multimodal therapy. Neuro-Oncology. 17: 448-56. PMID 25395462 DOI: 10.1093/Neuonc/Nou279 |
0.344 |
|
| 2015 |
Patay Z, Orr BA, Shulkin BL, Hwang SN, Ying Y, Broniscer A, Boop FA, Ellison DW. Successive distinct high-grade gliomas in L-2-hydroxyglutaric aciduria. Journal of Inherited Metabolic Disease. 38: 273-7. PMID 25338511 DOI: 10.1007/S10545-014-9782-8 |
0.307 |
|
| 2015 |
Orr BA, Eberhart CG. Molecular pathways: not a simple tube--the many functions of blood vessels. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 18-23. PMID 25074609 DOI: 10.1158/1078-0432.Ccr-13-1641 |
0.448 |
|
| 2015 |
Kaur H, Hütt-Cabezas M, Taylor I, Asnaghi L, Rodriguez F, Orr BA, Eberhart CG, Raabe EH. Abstract 4222: Targeting HMGA2 suppresses GBM stemness, invasion and tumorigenicity Cancer Research. 75: 4222-4222. DOI: 10.1158/1538-7445.Am2015-4222 |
0.44 |
|
| 2015 |
Rubens J, Weingart M, Price A, Hutt-Cabezas M, Taylor I, Allen S, Orr B, Eberhart C, Raabe E. Abstract 3272: Targeting LIN28 and the RAS/MAP kinase pathway in atypical teratoid rhabdoid tumors Cancer Research. 75: 3272-3272. DOI: 10.1158/1538-7445.Am2015-3272 |
0.417 |
|
| 2015 |
Lin CY, Erkek S, Tong Y, Yang L, Federation AJ, Zapatka M, Haldipur P, Kawauchi D, Risch T, Warnatz H, Worst B, Ju B, Orr BA, Zeid R, Polaski DR, et al. Abstract LB-B23: Medulloblastoma regulatory circuitries reveal subgroup-specific cellular origins Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-Lb-B23 |
0.311 |
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| 2015 |
Sturm D, Orr B, Hovestadt V, Jones DTW, Capper D, Lichter P, Korshunov A, Pfister S, Ellison D, Kool M. Mpth-15Molecular Reclassification Of Cns-Primitive Neuroectodermal Tumors Into Well-Known And Novel Tumor Entities Neuro-Oncology. 17. DOI: 10.1093/Neuonc/Nov222.15 |
0.479 |
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| 2015 |
Friedman G, Nan L, Moore B, Etminan T, Orr B, Chewning J, Crossman D, Gillespie GY. PM-05 * TUMOR LOCATION REMODELS TRANSCRIPTOMIC PROFILES IN A PEDIATRIC MEDULLOBLASTOMA XENOGRAFT Neuro-Oncology. 17: iii32-iii32. DOI: 10.1093/Neuonc/Nov061.127 |
0.475 |
|
| 2014 |
Kahlert UD, Suwala AK, Raabe EH, Siebzehnrubl FA, Suarez MJ, Orr BA, Bar EE, Maciaczyk J, Eberhart CG. ZEB1 Promotes Invasion in Human Fetal Neural Stem Cells and Hypoxic Glioma Neurospheres. Brain Pathology (Zurich, Switzerland). PMID 25521330 DOI: 10.1111/Bpa.12240 |
0.418 |
|
| 2014 |
Robinson GW, Orr BA, Gajjar A. Complete clinical regression of a BRAF V600E-mutant pediatric glioblastoma multiforme after BRAF inhibitor therapy. Bmc Cancer. 14: 258. PMID 24725538 DOI: 10.1186/1471-2407-14-258 |
0.434 |
|
| 2014 |
Ju B, Chen W, Spitsbergen JM, Lu J, Vogel P, Peters JL, Wang YD, Orr BA, Wu J, Henson HE, Jia S, Parupalli C, Taylor MR. Activation of Sonic hedgehog signaling in neural progenitor cells promotes glioma development in the zebrafish optic pathway. Oncogenesis. 3: e96. PMID 24686726 DOI: 10.1038/oncsis.2014.10 |
0.311 |
|
| 2014 |
Rodić N, Sharma R, Sharma R, Zampella J, Dai L, Taylor MS, Hruban RH, Iacobuzio-Donahue CA, Maitra A, Torbenson MS, Goggins M, Shih IeM, Duffield AS, Montgomery EA, Gabrielson E, ... ... Orr BA, et al. Long interspersed element-1 protein expression is a hallmark of many human cancers. The American Journal of Pathology. 184: 1280-6. PMID 24607009 DOI: 10.1016/J.Ajpath.2014.01.007 |
0.333 |
|
| 2014 |
Lim KS, Lim KJ, Price AC, Orr BA, Eberhart CG, Bar EE. Inhibition of monocarboxylate transporter-4 depletes stem-like glioblastoma cells and inhibits HIF transcriptional response in a lactate-independent manner. Oncogene. 33: 4433-41. PMID 24077291 DOI: 10.1038/Onc.2013.390 |
0.402 |
|
| 2014 |
Kaur H, Hütt M, Mao X, Orr BA, Eberhart CG, Raabe EH. Abstract 3031: HMGA2 promotes invasion and stemness in glioblastoma Cancer Research. 74: 3031-3031. DOI: 10.1158/1538-7445.Am2014-3031 |
0.418 |
|
| 2013 |
Odia Y, Orr BA, Bell WR, Eberhart CG, Rodriguez FJ. cMYC expression in infiltrating gliomas: associations with IDH1 mutations, clinicopathologic features and outcome. Journal of Neuro-Oncology. 115: 249-59. PMID 23934175 DOI: 10.1007/S11060-013-1221-4 |
0.383 |
|
| 2013 |
Mao XG, Hütt-Cabezas M, Orr BA, Weingart M, Taylor I, Rajan AK, Odia Y, Kahlert U, Maciaczyk J, Nikkhah G, Eberhart CG, Raabe EH. LIN28A facilitates the transformation of human neural stem cells and promotes glioblastoma tumorigenesis through a pro-invasive genetic program. Oncotarget. 4: 1050-64. PMID 23846349 DOI: 10.18632/Oncotarget.1131 |
0.483 |
|
| 2013 |
Chu Q, Orr BA, Semenkow S, Bar EE, Eberhart CG. Prolonged inhibition of glioblastoma xenograft initiation and clonogenic growth following in vivo Notch blockade. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 3224-33. PMID 23630166 DOI: 10.1158/1078-0432.Ccr-12-2119 |
0.457 |
|
| 2013 |
Nguyen DN, Heaphy CM, de Wilde RF, Orr BA, Odia Y, Eberhart CG, Meeker AK, Rodriguez FJ. Molecular and morphologic correlates of the alternative lengthening of telomeres phenotype in high-grade astrocytomas. Brain Pathology (Zurich, Switzerland). 23: 237-43. PMID 22928601 DOI: 10.1111/J.1750-3639.2012.00630.X |
0.32 |
|
| 2013 |
Larson JD, McEachron TA, Qu C, Zhu X, Diaz AK, Ellison DW, Orr BA, Baker SJ. Abstract A15: Variant histone H3 mutations associate with histone modification, DNA methylation, and gene expression changes in pediatric high-grade gliomas Cancer Research. 73. DOI: 10.1158/1538-7445.Cec13-A15 |
0.308 |
|
| 2013 |
Lim KS, Lim KJ, Orr BA, Price AC, Eberhart CG, Bar EE. Abstract 2930: Silencing MCT4 inhibits GBM growth, HIF response, and CD133-positive fraction in a lactate-independent fashion. Cancer Research. 73: 2930-2930. DOI: 10.1158/1538-7445.Am2013-2930 |
0.388 |
|
| 2012 |
Orr BA, Haffner MC, Nelson WG, Yegnasubramanian S, Eberhart CG. Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma. Plos One. 7: e41036. PMID 22829908 DOI: 10.1371/Journal.Pone.0041036 |
0.444 |
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| 2012 |
Kahlert UD, Maciaczyk D, Doostkam S, Orr BA, Simons B, Bogiel T, Reithmeier T, Prinz M, Schubert J, Niedermann G, Brabletz T, Eberhart CG, Nikkhah G, Maciaczyk J. Activation of canonical WNT/β-catenin signaling enhances in vitro motility of glioblastoma cells by activation of ZEB1 and other activators of epithelial-to-mesenchymal transition. Cancer Letters. 325: 42-53. PMID 22652173 DOI: 10.1016/J.Canlet.2012.05.024 |
0.372 |
|
| 2012 |
Baia GS, Caballero OL, Orr BA, Lal A, Ho JS, Cowdrey C, Tihan T, Mawrin C, Riggins GJ. Yes-associated protein 1 is activated and functions as an oncogene in meningiomas. Molecular Cancer Research : McR. 10: 904-13. PMID 22618028 DOI: 10.1158/1541-7786.Mcr-12-0116 |
0.42 |
|
| 2012 |
Orr BA, Eberhart CG. Nature versus nurture in glioblastoma: microenvironment and genetics can both drive mesenchymal transcriptional signature. The American Journal of Pathology. 180: 1768-71. PMID 22449951 DOI: 10.1016/J.Ajpath.2012.03.001 |
0.466 |
|
| 2012 |
Zuniga MG, Orr BA, Chang SS, Tufano RP. Suboccipital malignant solitary fibrous tumor: report of a case. Ear, Nose, & Throat Journal. 91: E25-7. PMID 22359142 DOI: 10.1177/014556131209100220 |
0.411 |
|
| 2012 |
Rodriguez FJ, Orr BA, Ligon KL, Eberhart CG. Neoplastic cells are a rare component in human glioblastoma microvasculature. Oncotarget. 3: 98-106. PMID 22298889 DOI: 10.18632/Oncotarget.427 |
0.387 |
|
| 2012 |
Siu IM, Salmasi V, Orr BA, Zhao Q, Binder ZA, Tran C, Ishii M, Riggins GJ, Hann CL, Gallia GL. Establishment and characterization of a primary human chordoma xenograft model. Journal of Neurosurgery. 116: 801-9. PMID 22283186 DOI: 10.3171/2011.12.Jns111123 |
0.448 |
|
| 2012 |
Lim KS, Lim KJ, Orr BA, Price AC, Eberhart CG, Bar EE. Abstract 3483: Inhibition of Monocarboxylate Transporter 4 (MCT4) targets stem-like cells in glioblastoma Cancer Research. 72: 3483-3483. DOI: 10.1158/1538-7445.Am2012-3483 |
0.407 |
|
| 2011 |
Mehta VA, Kretzer RM, Orr B, Jallo GI. Primary intramedullary spinal germ cell tumors World Neurosurgery. 76: 478.E1-478.E6. PMID 22152582 DOI: 10.1016/J.Wneu.2011.01.024 |
0.407 |
|
| 2011 |
Orr BA, Bai H, Odia Y, Jain D, Anders RA, Eberhart CG. Yes-associated protein 1 is widely expressed in human brain tumors and promotes glioblastoma growth. Journal of Neuropathology and Experimental Neurology. 70: 568-77. PMID 21666501 DOI: 10.1097/Nen.0B013E31821Ff8D8 |
0.422 |
|
| 2011 |
Li J, Recinos PF, Orr BA, Burger PC, Jallo GI, Recinos VR. Papillary tumor of the pineal region in a 15-month-old boy. Journal of Neurosurgery. Pediatrics. 7: 534-8. PMID 21529195 DOI: 10.3171/2011.2.Peds10434 |
0.478 |
|
| 2006 |
Jiang X, Orr BA, Kranz DM, Shapiro DJ. Estrogen induction of the granzyme B inhibitor, proteinase inhibitor 9, protects cells against apoptosis mediated by cytotoxic T lymphocytes and natural killer cells. Endocrinology. 147: 1419-26. PMID 16306080 DOI: 10.1210/En.2005-0996 |
0.321 |
|
| 2004 |
Roy EJ, Gawlick U, Orr BA, Kranz DM. Folate-mediated targeting of T cells to tumors. Advanced Drug Delivery Reviews. 56: 1219-31. PMID 15094217 DOI: 10.1016/J.Addr.2004.01.006 |
0.735 |
|
| 2003 |
Orr BA, Carr LM, Wittrup KD, Roy EJ, Kranz DM. Rapid method for measuring ScFv thermal stability by yeast surface display. Biotechnology Progress. 19: 631-8. PMID 12675608 DOI: 10.1021/Bp0200797 |
0.533 |
|
| 2000 |
Roy EJ, Gawlick U, Orr BA, Rund LA, Webb AG, Kranz DM. IL-12 treatment of endogenously arising murine brain tumors. Journal of Immunology (Baltimore, Md. : 1950). 165: 7293-9. PMID 11120864 DOI: 10.4049/Jimmunol.165.12.7293 |
0.748 |
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