Year |
Citation |
Score |
2020 |
Shi C, Miller BR, Alexander EM, Gulick AM, Aldrich CC. Design, Synthesis and Biophysical Evaluation of Mechanism-Based Probes for Condensation Domains of Nonribosomal Peptide Synthetases. Acs Chemical Biology. PMID 32568518 DOI: 10.1021/Acschembio.0C00411 |
0.544 |
|
2016 |
Miller BR, Drake EJ, Shi C, Aldrich CC, Gulick AM. Structures of a Nonribosomal Peptide Synthetase Module Bound to MbtH-Like Proteins Support a Highly Dynamic Domain Architecture. The Journal of Biological Chemistry. PMID 27597544 DOI: 10.1074/Jbc.M116.746297 |
0.53 |
|
2016 |
Kuhn ML, Alexander E, Minasov G, Page HJ, Warwrzak Z, Shuvalova L, Flores KJ, Wilson DJ, Shi C, Aldrich CC, Anderson WF. Structure of the Essential Mtb FadD32 Enzyme: A Promising Drug Target for Treating Tuberculosis. Acs Infectious Diseases. 2: 579-591. PMID 27547819 DOI: 10.1021/Acsinfecdis.6B00082 |
0.512 |
|
2016 |
Drake EJ, Miller BR, Shi C, Tarrasch JT, Sundlov JA, Allen CL, Skiniotis G, Aldrich CC, Gulick AM. Structures of two distinct conformations of holo-non-ribosomal peptide synthetases. Nature. 529: 235-8. PMID 26762461 DOI: 10.1038/Nature16163 |
0.529 |
|
2016 |
Anand A, Verma P, Singh A, Shi C, Kaur H, Chawla M, Kumar D, Yang Y, Dash D, Singh A, Ojha A, Aldrich C, Gokhale R. Role of polyketide quinone in the maintenance of mycobacterial bioenergetics in oxygen-deficient niches F1000research. 5. DOI: 10.7490/F1000Research.1112354.1 |
0.443 |
|
2015 |
Srivastava S, Chaudhary S, Thukral L, Shi C, Gupta RD, Gupta R, Priyadarshan K, Vats A, Haque AS, Sankaranarayanan R, Natarajan VT, Sharma R, Aldrich CC, Gokhale RS. Unsaturated Lipid Assimilation by Mycobacteria Requires Auxiliary cis-trans Enoyl CoA Isomerase. Chemistry & Biology. PMID 26628360 DOI: 10.1016/J.Chembiol.2015.10.009 |
0.496 |
|
2015 |
Anand A, Verma P, Singh AK, Kaushik S, Pandey R, Shi C, Kaur H, Chawla M, Elechalawar CK, Kumar D, Yang Y, Bhavesh NS, Banerjee R, Dash D, Singh A, et al. Polyketide Quinones Are Alternate Intermediate Electron Carriers during Mycobacterial Respiration in Oxygen-Deficient Niches. Molecular Cell. PMID 26585386 DOI: 10.1016/J.Molcel.2015.10.016 |
0.486 |
|
2014 |
Schiaffo CE, Shi C, Xiong Z, Olin M, Ohlfest JR, Aldrich CC, Ferguson DM. Structure-activity relationship analysis of imidazoquinolines with Toll-like receptors 7 and 8 selectivity and enhanced cytokine induction. Journal of Medicinal Chemistry. 57: 339-47. PMID 24383475 DOI: 10.1021/Jm4004957 |
0.472 |
|
2013 |
Shi C, Tiwari D, Wilson DJ, Seiler CL, Schnappinger D, Aldrich CC. Bisubstrate Inhibitors of Biotin Protein Ligase in Mycobacterium tuberculosis Resistant to Cyclonucleoside Formation. Acs Medicinal Chemistry Letters. 4. PMID 24363833 DOI: 10.1021/Ml400328A |
0.507 |
|
2013 |
Wilson DJ, Shi C, Teitelbaum AM, Gulick AM, Aldrich CC. Characterization of AusA: a dimodular nonribosomal peptide synthetase responsible for the production of aureusimine pyrazinones. Biochemistry. 52: 926-37. PMID 23302043 DOI: 10.1021/Bi301330Q |
0.545 |
|
2012 |
Shi C, Xiong Z, Chittepu P, Aldrich CC, Ohlfest JR, Ferguson DM. Discovery of Imidazoquinolines with Toll-Like Receptor 7/8 Independent Cytokine Induction. Acs Medicinal Chemistry Letters. 3: 501-504. PMID 22837811 DOI: 10.1021/Ml300079E |
0.48 |
|
2012 |
Shi C, Aldrich CC. Design and synthesis of potential mechanism-based inhibitors of the aminotransferase BioA involved in biotin biosynthesis. The Journal of Organic Chemistry. 77: 6051-8. PMID 22724679 DOI: 10.1021/Jo3008435 |
0.506 |
|
2012 |
Mitchell CA, Shi C, Aldrich CC, Gulick AM. Structure of PA1221, a nonribosomal peptide synthetase containing adenylation and peptidyl carrier protein domains. Biochemistry. 51: 3252-63. PMID 22452656 DOI: 10.1021/Bi300112E |
0.53 |
|
2012 |
Sundlov JA, Shi C, Wilson DJ, Aldrich CC, Gulick AM. Structural and functional investigation of the intermolecular interaction between NRPS adenylation and carrier protein domains. Chemistry & Biology. 19: 188-98. PMID 22365602 DOI: 10.1016/J.Chembiol.2011.11.013 |
0.533 |
|
2011 |
Shi C, Geders TW, Park SW, Wilson DJ, Boshoff HI, Abayomi O, Barry CE, Schnappinger D, Finzel BC, Aldrich CC. Mechanism-based inactivation by aromatization of the transaminase BioA involved in biotin biosynthesis in Mycobaterium tuberculosis. Journal of the American Chemical Society. 133: 18194-201. PMID 21988601 DOI: 10.1021/Ja204036T |
0.515 |
|
2011 |
Wilson DJ, Shi C, Duckworth BP, Muretta JM, Manjunatha U, Sham YY, Thomas DD, Aldrich CC. A continuous fluorescence displacement assay for BioA: an enzyme involved in biotin biosynthesis. Analytical Biochemistry. 416: 27-38. PMID 21621502 DOI: 10.1016/J.Ab.2011.05.003 |
0.494 |
|
2010 |
Shi C, Aldrich CC. Efficient Pd-catalyzed coupling of tautomerizable heterocycles with terminal alkynes via C-OH bond activation using PyBrOP. Organic Letters. 12: 2286-9. PMID 20411949 DOI: 10.1021/Ol100657N |
0.48 |
|
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