Farokh J. Dotiwala, Ph.D.
Affiliations: | Molecular and Cell Biology | Brandeis University, Waltham, MA, United States |
Area:
DNA repairGoogle:
"Farokh Dotiwala"Parents
Sign in to add mentor| James E. Haber | grad student | 2009 | Brandeis | |
| (Nuclear and cytoplasmic control of the DNA damage checkpoint.) | ||||
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Publications
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| Crespo ÂC, Mulik S, Dotiwala F, et al. (2020) Decidual NK Cells Transfer Granulysin to Selectively Kill Bacteria in Trophoblasts. Cell |
| Junqueira C, Barbosa CRR, Costa PAC, et al. (2018) Cytotoxic CD8 T cells recognize and kill Plasmodium vivax-infected reticulocytes. Nature Medicine |
| Clayton KL, Collins DR, Lengieza J, et al. (2018) Resistance of HIV-infected macrophages to CD8 T lymphocyte-mediated killing drives activation of the immune system. Nature Immunology. 19: 475-486 |
| Dotiwala F, Sen Santara S, Binker-Cosen AA, et al. (2017) Granzyme B Disrupts Central Metabolism and Protein Synthesis in Bacteria to Promote an Immune Cell Death Program. Cell |
| Sula Karreci E, Eskandari SK, Dotiwala F, et al. (2017) Human regulatory T cells undergo self-inflicted damage via granzyme pathways upon activation. Jci Insight. 2 |
| Dotiwala F, Mulik S, Polidoro RB, et al. (2016) Killer lymphocytes use granulysin, perforin and granzymes to kill intracellular parasites. Nature Medicine. 22: 210-6 |
| Walch M, Dotiwala F, Mulik S, et al. (2015) Cytotoxic Cells Kill Intracellular Bacteria through Granulysin-Mediated Delivery of Granzymes. Cell. 161: 1229 |
| Dotiwala F, Fellay I, Filgueira L, et al. (2015) A High Yield and Cost-efficient Expression System of Human Granzymes in Mammalian Cells. Journal of Visualized Experiments : Jove. e52911 |
| Walch M, Dotiwala F, Mulik S, et al. (2014) Cytotoxic cells kill intracellular bacteria through granulysin-mediated delivery of granzymes. Cell. 157: 1309-23 |
| Lee MN, Roy M, Ong SE, et al. (2013) Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach. Nature Immunology. 14: 179-85 |