Lauren E. Brown, Ph.D.
Affiliations: | University of California, Santa Cruz, Santa Cruz, CA, United States |
Area:
Synthetic organic chemistry; heterocyclic chemistry, bio-organic chemistryGoogle:
"Lauren Brown"Parents
Sign in to add mentor| Nicos A. Petasis | research assistant | 2001-2003 | USC | |
| Joseph P. Konopelski | grad student | 2009 | UC Santa Cruz | |
| (Synthetic studies toward welwistatin, psymberin and a protective pharmaceutical.) | ||||
| Scott E. Schaus | post-doc | 2009-2012 | Boston University | |
| John A. Porco | research scientist | 2012-2014 | Boston University | |
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Publications
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| Laflamme B, Blackman C, Loranger M, et al. (2025) A cationic amphiphilic drug synergizes with strobilurin fungicides to control fungal-borne plant diseases. Cell Chemical Biology |
| Goldstein SI, Fan AC, Wang Z, et al. (2025) Discovery of RNA-Protein Molecular Clamps Using Proteome-Wide Stability Assays. Journal of Proteome Research |
| Conley JF, Brown LE, McNeely JH, et al. (2025) Structural Basis for the Improved RNA Clamping of Amidino-Rocaglates to eIF4A1. Acs Omega. 10: 5795-5808 |
| Oo A, Borge A, Lee RCH, et al. (2025) In Vitro Discovery of a Therapeutic Lead for HFMD From a Library Screen of Rocaglates/Aglains. Journal of Medical Virology. 97: e70228 |
| Avancha A, Hoyt H, Bhave K, et al. (2024) Glabridin Hypnosis in Zebrafish Larvae Is Associated With Effects on Multiple Anesthetic Target Receptors. Anesthesia and Analgesia |
| Wang Z, Thakare RP, Chitale S, et al. (2024) Identification of Rocaglate Acyl Sulfamides as Selective Inhibitors of Glioblastoma Stem Cells. Acs Central Science. 10: 1640-1656 |
| Keiser PT, Zhang W, Ricca M, et al. (2024) Amidino-Rocaglates (ADRs), a class of synthetic rocaglates, are potent inhibitors of SARS-CoV-2 replication through inhibition of viral protein synthesis. Antiviral Research. 105976 |
| Thirman HL, Hayes MJ, Brown LE, et al. (2024) Single Cell Profiling Distinguishes Leukemia-Selective Chemotypes. Biorxiv : the Preprint Server For Biology |
| Volegova MP, Brown LE, Banerjee U, et al. (2024) The MYCN 5' UTR as a therapeutic target in neuroblastoma. Cell Reports. 43: 114134 |
| Goldstein SI, Fan AC, Wang Z, et al. (2024) Proteomic Discovery of RNA-Protein Molecular Clamps Using a Thermal Shift Assay with ATP and RNA (TSAR). Biorxiv : the Preprint Server For Biology |