Jonathan T. Kern, Ph.D.
Affiliations: | University of Texas at Austin, Austin, Texas, U.S.A. |
Area:
Synthetic Medicinal Chemistry, Nucleic Acids Chemistry, Natural Products Chemistry, Computational ChemistryGoogle:
"Jonathan Kern"Parents
Sign in to add mentorSean M. Kerwin | grad student | 2002 | UT Austin | |
(Studies on 3,4,9,10-perylenetetracarboxylic acid diimide based ligands as G -quadruplex DNA interactive agents.) |
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Publications
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Tuesuwan B, Kern JT, Thomas PW, et al. (2008) Simian virus 40 large T-antigen G-quadruplex DNA helicase inhibition by G-quadruplex DNA-interactive agents Biochemistry. 47: 1896-1909 |
Mazzitelli CL, Brodbelt JS, Kern JT, et al. (2006) Evaluation of binding of perylene diimide and benzannulated perylene diimide ligands to DNA by electrospray ionization mass spectrometry. Journal of the American Society For Mass Spectrometry. 17: 593-604 |
Kern JT, Kerwin SM. (2002) The aggregation and G-quadruplex DNA selectivity of charged 3,4,9,10-perylenetetracarboxylic acid diimides Bioorganic and Medicinal Chemistry Letters. 12: 3395-3398 |
Kern JT, Thomas PW, Kerwin SM. (2002) The relationship between ligand aggregation and G-quadruplex DNA selectivity in a series of 3,4,9,10-perylenetetracarboxylic acid diimides Biochemistry. 41: 11379-11389 |
Kerwin SM, Chen G, Kern JT, et al. (2002) Perylene diimide G-quadruplex DNA binding selectivity is mediated by ligand aggregation Bioorganic and Medicinal Chemistry Letters. 12: 447-450 |
Kerwin SM, Sun D, Kern JT, et al. (2001) G-quadruplex DNA binding by a series of carbocyanine dyes Bioorganic and Medicinal Chemistry Letters. 11: 2411-2414 |
Kumar D, Kanz B, Mamiya BM, et al. (2001) Synthesis of a phosphoramidate pro-drug of 6-thio-7-deaza-2′-deoxyguanosine (TDG): A regioselective phosphorylation Tetrahedron Letters. 42: 565-567 |
McPhee MM, Kern JT, Hoster BC, et al. (2000) Propargylic sulfone-armed lariat crown ethers: Alkali metal ion- regulated DNA cleavage agents Bioorganic Chemistry. 28: 98-118 |